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Journal articles on the topic '59.9 (043.2)'

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Published: 30 May 2022

Last updated: 31 July 2025

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1

Edwards, S. A., A. W. Armsby, and H. H. Spechter. "Effects of floor area allowance on performance of growing pigs kept on fully slatted floors." Animal Production 46, no. 3 (1988): 453–59. http://dx.doi.org/10.1017/s0003356100019061.

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ABSTRACTThe experiment compared four different space allowances for growing pigs housed on fully slatted floors. Space allowance (A m2) was defined in relation to live weight (M kg) of the pigs according to the equation A = kM0·67, using values for the constant (it) of 0·024, 0·027, 0·030 and 0·034. Six replicate pens of 12 pigs were housed on each treatment in a controlled environment building. Food was given ad libitum and from 34 kg until slaughter at 85 kg pigs were individually weighed each week and the pen size was adjusted according to the appropriate equation. Increasing space allowanc

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Syndikus, Isabel, Joachim Kwok-Chiu Chan, Thelma Rowntree, Laura Howard, and John Staffurth. "Hypofractionated dose painting IMRT using 20 fractions for intermediate to high-risk localized prostate cancer: Two-year outcome data (BIOPROP20, NCT02125175)." Journal of Clinical Oncology 37, no. 7_suppl (2019): 59. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.59.

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59 Background: Prostate dose painting (boosting intra-prostatic tumour volumes) may improve biochemical relapse-free survival similar to whole organ dose-escalation without the associated increased toxicity. We present a pre-defined secondary endpoint of 2 year outcome for patients at one of two UK centres in a phase II trial (BIOPROP20) on dose-painting radiotherapy for intermediate to high risk patients treated with 60Gy/20# and concurrent 68Gy boost. Methods: Pinnacle software was used for VMAT planning and boost volumes were outlined by18F choline PET/CT and mpMRI. Patients with positive l

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Sandjaja, Idrus Jus’at, Abas B. Jahari, et al. "Vitamin A-fortified cooking oil reduces vitamin A deficiency in infants, young children and women: results from a programme evaluation in Indonesia." Public Health Nutrition 18, no. 14 (2015): 2511–22. http://dx.doi.org/10.1017/s136898001400322x.

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AbstractObjectiveTo assess oil consumption, vitamin A intake and retinol status before and a year after the fortification of unbranded palm oil with retinyl palmitate.DesignPre–post evaluation between two surveys.SettingTwenty-four villages in West Java.SubjectsPoor households were randomly sampled. Serum retinol (adjusted for subclinical infection) was analysed in cross-sectional samples of lactating mothers (baselinen324/endlinen349), their infants aged 6–11 months (n318/n335) and children aged 12–59 months (n469/477), and cohorts of children aged 5–9 years (n186) and women aged 15–29 years

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Perzborn, Elisabeth, and Brigitte Arndt. "Antithrombotic Effects of Concomitant Administration of BAY 59–7939 with Enoxaparin or Heparin - Interaction Study." Blood 104, no. 11 (2004): 1863. http://dx.doi.org/10.1182/blood.v104.11.1863.1863.

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Abstract BAY 59–7939 is an oral, direct Factor Xa (FXa) inhibitor in development for the prevention and treatment of thromboembolic diseases. Current therapies include unfractionated heparin and low molecular weight heparins. Bridging therapy may be necessary when a patient receiving oral anticoagulation requires parenteral anticoagulants, or vice versa. The potential interaction, and feasibility of bridging therapy, using BAY 59–7939 and enoxaparin or heparin was investigated in a rat arteriovenous (AV)-shunt model. An AV shunt connected the right common carotid artery and the left jugular ve

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Petrylak, Daniel, Jitendra G. Gandhi, William R. Clark, et al. "A phase I/II study of safety and efficacy of orteronel (TAK-700), an oral, investigational, nonsteroidal 17,20-lyase inhibitor, with docetaxel and prednisone (DP) in metastatic castration-resistant prostate cancer (mCRPC): Updated phase II results." Journal of Clinical Oncology 31, no. 6_suppl (2013): 59. http://dx.doi.org/10.1200/jco.2013.31.6_suppl.59.

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59 Background: Orteronel is an investigational non-steroidal, selective inhibitor of 17,20-lyase, a key enzyme in the production of steroidal hormones. DP is currently an approved therapy in mCRPC; this phase 1/2 study examined orteronel + DP in men with mCRPC. Methods: Castrate men (testosterone [T] <50 ng/dL) with mCRPC, no prior chemotherapy and no ketoconazole/abiraterone received orteronel (400 mg BID) + D (75 mg/m2 q3w) + P (5 mg BID). The primary phase 2 objectives were tolerability, PK, serum PSA declines, and best PSA response. Secondary objectives included time to progression of P

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Marques, M. L., N. Pereira Da Silva, D. Van der Heijde, et al. "POS0974 LOW DOSE COMPUTED TOMOGRAPHY HOUNSFIELD UNITS: A RELIABLE METHODOLOGY FOR ASSESSING CHANGES IN VERTEBRAL BONE DENSITY IN RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 794.2–795. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2276.

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BackgroundAssessing local vertebral bone loss in radiographic axial spondyloarthritis (r-axSpA) poses challenges, namely because Dual-energy X-ray absorptiometry (DXA) only allows assessment of lumbar vertebrae. The measurement of Computed Tomography (CT) vertebral Hounsfield Units (HU) has been shown to correlate with vertebral bone density as measured by DXA in trauma patients. We have recently reported the excellent reliability of low dose CT (ldCT) HU measurements from C3 to L5 in patients with r-axSpA1; however, HU change scores have never been studied.ObjectivesTo describe ldCT HU change

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Harrison, S., U. Nandasoma, P. Sambi, et al. "POS0022 NAFLD IN PSORIATIC DISEASE: IDENTIFYING PATIENTS AT HIGH RISK OF SERIOUS LIVER DISEASE." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 217.1–217. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2510.

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BackgroundPatients with psoriatic disease(PsD) [psoriasis(PsO) and psoriatic arthritis(PsA)] are at greater risk of non-alcoholic fatty liver disease(NAFLD) and NAFLD-associated fibrosis/cirrhosis compared with the general population and other inflammatory arthritis(1) independent of disease-modifying medications [biological(b)DMARDs or methotrexate(MTX)][2]. Conversely, using these medications in patients with significant NAFLD might accelerate progression to fibrosis/cirrhosis[1]. The Leeds Teaching Hospitals NHS Trust(LTHT) NAFLD screening pathway is not validated in PsD and may underestima

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Arablinskiy, A. V., and V. B. Rumer. "Urgent surgery – the role of computed tomography." Medical Visualization 22, no. 6 (2019): 59–68. http://dx.doi.org/10.24835/1607-0763-2018-6-59-68.

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Introduction.Acute abdomen is a complex condition that demands urgent diagnostics and treatment.The proposeof the study based on data we got in the Radiology Department of S.P. Botkin Municipal Clinical Hospital is to evaluate the role of computed tomography in acute abdomen diagnostics.Materials and methods. 637 acute abdomen patient`s data were retrospectively analyzed, provided in the term from January 2017 to January 2018. The average age was 53 years old, from 18 to 98 y.o. Male to female ratio was 1:1,51, male – 383, female – 254. Inclusion criteria was acute abdomen clinical presentatio

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Yoh, Kyung Ah, Ho Sup Lee, Lee Chun Park, Eun Mi Lee, Dae Jin Park, and Yang Soo Kim. "Prognostic Significance of Elevated Serum Ferritin Before Chemotherapy in Patients with Non-Hodgkin's Lymphoma." Blood 120, no. 21 (2012): 5099. http://dx.doi.org/10.1182/blood.v120.21.5099.5099.

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Abstract Abstract 5099 Background: Elevated ferritin level before stem cell transplantation was documented an adverse prognostic factor for patients undergoing hematopoietic stem cell transplantation for hematologic malignancies. Until now, there have been reported few studies which suggested high serum ferritin level were associated with worse outcomes for lymphoma. The purpose of this study was to find the significance of high levels of serum ferritin for predicting survival outcome in patients with non-Hodgkin's lymphoma (NHL). Methods: A total of 267 patients who newly diagnosed and receiv

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Bowmaker, Graham A., Effendy, Robert D. Hart, John D. Kildea, and Allan H. White. "Lewis-Base Adducts of Group 11 Metal(I) Compounds. LXXIII Synthesis, Spectroscopy and Structural Systematics of New 1 : 1 'Cubane' Tetramers of Copper(I) and Silver(I) Halides with Triphenylarsine." Australian Journal of Chemistry 50, no. 6 (1997): 653. http://dx.doi.org/10.1071/c96039.

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Syntheses and room-temperature single-crystal X-ray structural characterization of a number of 1 : 1 ‘cube tetramer’ adducts of copper(I) and silver(I) halides, MX, with triphenylarsine, AsPh3, are recorded, being [XM(AsPh3)]4. The CuBr adduct, obtained unsolvated from toluene, orthorhombic Pbcn, a 17·844(5), b 20·778(8), c 18·430(4) Å, Z = 4 tetramers, conventional R on |F| 0·058 for No 1309 independent ‘observed’ reflctions (I > 3σ(I)), is isomorphous with previously recorded [ClAg(PPh3)]4, the tetramer having crystallographically imposed 2 symmetry. The CuI adduct, previously recorded as

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Djaja, Sebastian, Ahmad Tobroni, Dadik Agus Soenjoto, and Bambang Suprapto. "041. A Case of Cholangiocarcinoma in A Young Adolescent." JBN (Jurnal Bedah Nasional) 8, no. 2 (2024): 41. http://dx.doi.org/10.24843/jbn.2024.v08.is02.p041.

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Background: Cholangiocarcinoma usually occurs in 50-70 years age group. Recent study showed an increased incidence in younger age group. We describe a case of Cholangiocarcinoma in an adolescent girl in order to understand its natural history. Case: A 16 year old girl presented with 2 months history of jaundice, itchyness, right upper quadrant abdominal pain, pale stool and dark urine. Initial investigation showed : Total Bilirubin 8.87, (Direct 3.53, Indirect 12.40), SGOT 75, SGPT 56, ALP 240, GGT 59, Hepatitis B and C negative, AFP 1.96, CA19-9 3.1, and CEA 5.1. Imaging showed dilated hepati

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Murphy, Mary M., Leila M. Barraj, Lindsey D. Toth, Laura S. Harkness, and Douglas R. Bolster. "Daily intake of dairy products in Brazil and contributions to nutrient intakes: a cross-sectional study." Public Health Nutrition 19, no. 3 (2015): 393–400. http://dx.doi.org/10.1017/s1368980015001780.

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AbstractObjectiveDairy products are sources of protein and micronutrients important in a healthy diet. The purpose of the present analysis was to estimate consumption of dairy products by Brazilians and identify contributions of dairy products to nutrient intakes.DesignDairy consumption data were obtained from 24 h dietary records. Dairy products were defined as milk (including flavoured), cheese and yoghurt. Estimates of dairy product intakes were generated for all individuals, individuals in urban and rural households and for age groups 10–18 years, 19–59 years and ≥60 years. Contributions t

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Frykberg, Robert G., Joel Bowen, Jared Hall, Arthur Tallis, Edward Tierney, and Denise Freeman. "Prevalence of Equinus in Diabetic versus Nondiabetic Patients." Journal of the American Podiatric Medical Association 102, no. 2 (2012): 84–88. http://dx.doi.org/10.7547/1020084.

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Background: There are no conclusive data to support the contention that diabetic patients have an increased frequency of ankle equinus compared with their nondiabetic counterparts. Additionally, a presumed contributing cause of foot ulceration is ankle joint equinus. Therefore, we sought to determine whether persons with diabetes have a higher prevalence of ankle joint equinus than do nondiabetic persons. Methods: A prospective pilot survey of 102 outpatients (43 diabetic and 59 nondiabetic) was conducted. Demographic and historical data were obtained. Each patient underwent a standard lower-e

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Cazes, Cécile, Kevin Phelan, Victoire Hubert, et al. "Optimising Malnutrition Treatment in Children 6–59 Months-OptiMA-DRC: Primary Outcome of a Randomised Control Trial in Democratic Republic of Congo." Current Developments in Nutrition 5, Supplement_2 (2021): 111. http://dx.doi.org/10.1093/cdn/nzab035_019.

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Abstract Objectives The main objective was to compare the OptiMA strategy- ie.supplementing with ready-to-use therapeutic food at a gradually reduced doses- with the current national standard protocol. Methods This non-inferiority, individually randomised controlled clinical trial was conducted in the Democratic Republic of Congo. Children 6–59 months with MUAC &lt; 125 mm or weight-for-height Zscore&lt; −3 or oedema and without medical complication were randomized to either OptiMA or standard arm and followed for 6 months. The main outcome was a binary composite indicator at 6-months

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Adinolfi, A., S. Sirotti, G. Sakellariou, et al. "POS1141 ASSESSING RELEVANT JOINTS FOR MONITORING CPPD DISEASE: A SYSTEMATIC LITERATURE REVIEW OF IMAGING TECHNIQUES BY THE OMERACT ULTRASOUND – CPPD SUBGROUP." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 850.1–850. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3153.

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Background:Imaging has been extensively used for the Calcium Pyrophosphate Deposition Disease (CPPD) diagnosis but the prevalence of joint calcifications at imaging in CPPD patients has not been thoroughly assessed.Objectives:This systematic literature review (SLR) is aimed to estimate the prevalence of calcium crystal deposition in peripheral joints by imaging in suspected or definite CPPD patients to establish relevant joints for CPPD monitoringMethods:After defining PICOs, Pubmed and Embase were searched from inception to October 2020 for identifying studies that evaluated the use of Conven

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Morales, Serafin, Isabel Blancas, Maria Luisa Gonzalvez, et al. "Efficacy and safety of weekly oral vinorelbine (NVBO) as single agent in first- or second-line metastatic breast cancer (MBC)." Journal of Clinical Oncology 30, no. 15_suppl (2012): e11545-e11545. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e11545.

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e11545 Background: NVBO has shown high activity and good safety profile when given as single agent chemotherapy (CT) for MBC. Oral CT formulations allow maintenance of quality of live and minimal interference with a normal lifestyle. Methods: Main inclusion criteria for this retrospective study were: Histologically or citologically confirmed MBC, no more than 1 prior CT line for MBC; prior (neo)adjuvant CT, hormonetherapy or radiotherapy allowed; adequate bone marrow, kidney and liver function. The study protocol was approved by an ethics committee. Data was collected from patients (p) treated

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L. Murray, Gary, and Joseph Colombo. "Ranolazine Improves Autonomic Balance in Heart Failure when added to Guideline-Driven Therapy." Clinical Cardiology and Cardiovascular Interventions 3, no. 2 (2020): 01–11. http://dx.doi.org/10.31579/2641-0419/045.

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Background: The effect of ranolazine (RAN) on cardiac autonomic balance in congestive heart failure (CHF) was studied. Methods: Fifty-four CHF patients were randomized to (1) open-label RAN (RANCHF) added to usual therapy vs. (2) usual therapy (NORANCHF). Parasympathetic and sympathetic (P&S) measurements were taken at baseline and at 12 months. Results: A total of 16/27 (59%) patients in both groups had initially abnormal P&S measures, including high sympathovagal balance (SB), cardiovascular autonomic neuropathy (CAN) or both. High SB normalized in 10/12 (83%) RANCHF patients vs. 2/1

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Delgado-Guay, Marvin Omar, Alejandra Palma, Eva Rossina Duarte, et al. "Spirituality, religiosity, spiritual pain, and quality of life among caregivers of Latin American patients with advanced cancer: A multicenter study." Journal of Clinical Oncology 34, no. 26_suppl (2016): 245. http://dx.doi.org/10.1200/jco.2016.34.26_suppl.245.

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245 Background: Caregivers of cancer patients often face physical, and psychosocial hardship. The association between spirituality (S), religiosity (R), spiritual pain (SP), coping, and quality of life (QOL) have not been well characterized. The main purpose of this multicenter study was to determine these associations among LACs. Methods: We interviewed 319 LACs at palliative care clinics in Chile, Guatemala, and the US. LACs completed FICA (S/R assessment), ESAS–FS, PSWQ (worry), B-COPE/B-R-COPE (coping), and FACIT-Sp (spiritual well-being). Results: Median age 47 y, IQR=36, 59; 231 (73%) fe

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Oneda, Bruna, Claudia L. M. Forjaz, Fernanda R. Bernardo, et al. "Low-dose estrogen therapy does not change postexercise hypotension, sympathetic nerve activity reduction, and vasodilation in healthy postmenopausal women." American Journal of Physiology-Heart and Circulatory Physiology 295, no. 4 (2008): H1802—H1808. http://dx.doi.org/10.1152/ajpheart.01222.2007.

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The aim of this study was to determine whether estrogen therapy enhances postexercise muscle sympathetic nerve activity (MSNA) decrease and vasodilation, resulting in a greater postexercise hypotension. Eighteen postmenopausal women received oral estrogen therapy (ET; n = 9, 1 mg/day) or placebo ( n = 9) for 6 mo. They then participated in one 45-min exercise session (cycle ergometer at 50% of oxygen uptake peak) and one 45-min control session (seated rest) in random order. Blood pressure (BP, oscillometry), heart rate (HR), MSNA (microneurography), forearm blood flow (FBF, plethysmography), a

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Rumsey, Michael S., Mark D. Welch, John Spratt, and Annette K. Kleppe. "Grguricite, CaCr2(CO3)2(OH)4.4H2O, a new alumohydrocalcite analogue." Mineralogical Magazine 84, no. 5 (2020): 778–84. http://dx.doi.org/10.1180/mgm.2020.66.

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AbstractThe occurrence and characterisation of a new member of the dundasite group are reported. Grguricite, ideally CaCr2(CO3)2(OH)4⋅4H2O, is the Cr analogue of alumohydrocalcite, CaAl2(CO3)2(OH)4⋅4H2O and occurs as lilac crusts of very fine-grained crystalline aggregates in the Pb–Ba–V mineralisation found at the Adeghoual Mine, Mibladen, Morocco (32°46′0″N, 4°37′59″W). The identification was based upon a close match with the powder X-ray diffraction data for alumohydrocalcite, the confirmation of anion components identified by Raman spectroscopy and the cation composition determined by elec

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May, Michael S., Liam James Stanton, Jacob K. Jamison, et al. "Recurrence patterns and surveillance strategies in long-term survivors of resected pancreatic cancer." Journal of Clinical Oncology 42, no. 16_suppl (2024): e16361-e16361. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e16361.

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e16361 Background: Pancreatic ductal adenocarcinoma (PDA) is the third leading cause of cancer-related mortality in the United States. After resection, the 2-year disease-free survival is < 50%. Surveillance guidelines after resection vary significantly between expert groups. The level of evidence is particularly weak for patients who are alive and disease-free after 2 years. Our objective was to report rates and predictors of recurrence in this population. Methods: We reviewed all patients who underwent resection of stage I-III PDA at Columbia University Irving Medical Center from 2011-202

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Moulton, C. D., L. Murray, K. Winkley, S. A. Amiel, K. Ismail, and A. Patel. "Depression and change in occupational functioning in type 2 diabetes." Occupational Medicine 69, no. 5 (2019): 322–28. http://dx.doi.org/10.1093/occmed/kqz072.

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AbstractBackgroundThe effect of depression on both employment and productivity in type 2 diabetes (T2D) is poorly understood.AimsWe tested whether depressive symptoms at diagnosis of T2D are associated with change in employment status and productivity over 2-year follow-up.MethodsIn a prospective analysis of working-age (18–63 years) people with newly diagnosed T2D recruited from primary care, we tested the association between depressive symptoms at diagnosis of T2D (baseline) and employment rates over 2 years. Using the Patient Health Questionnaire-9, depressive symptoms were measured categor

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Usenko, O. Yu, O. A. Lavryk, A. Yu Zgonnyk, M. V. Manoylo та A. S. Lavryk. "Модифіковане біліопанкреатичне шунтування в лікуванні метаболічного синдрому та цукрового діабету 2-го типу у пацієнтів з морбідним ожирінням". Klinicheskaia khirurgiia 85, № 10 (2018): 5–9. http://dx.doi.org/10.26779/2522-1396.2018.10.05.

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Мета. Вивчення впливу операції біліопанкреатичного шунтування (БПШ) на перебіг метаболічного синдрому (МС) у хворих з морбідним ожирінням (МО). Матеріали і методи. Проаналізовано результати хірургічного лікування 76 хворих з МО, яким виконали операцію БПШ в Інституті. Вік хворих коливався від 23 до 65 років, середній індекс маси тіла (ІМТ) становив 57 (44 - 87) кг/м2. Артеріальну гіпертензію мали 49 (64%), дисліпідемію - 53 (70%), сонне апное - 13 (17%), астму - 14 (18%), цукровий діабет (ЦД) 2-го типу - 30 (39%) пацієнтів. Середній строк спостереження становив 36 міс. Визначали антропом

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Chen, Hua-Jun, Sheng Wang, Rong Su, et al. "BC3195, a novel ADC targeting CDH3: Preliminary results of a first-in-human phase I study in patients with advanced solid malignancies." Journal of Clinical Oncology 42, no. 16_suppl (2024): e15008-e15008. http://dx.doi.org/10.1200/jco.2024.42.16_suppl.e15008.

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e15008 Background: Cadherin-3 (CDH3), a calcium-dependent cell-cell adhesion glycoprotein, is overexpressed on lung, breast, ovarian, colorectal, pancreatic, head and neck and other malignancies, but with negligible expression on nonmalignant tissues, and associated with cancer aggressiveness, invasiveness, and poor prognosis. BC3195 is known as the only antibody drug conjugate (ADC) in clinical stage, targeting CDH3 with payload of monomethyl auristatin E (MMAE). Methods: A phase I, open-label, first in human study to evaluate the safety, tolerability, PK, and preliminary antitumor activity o

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Kaim, Arielle, Gal Zeevy, and Mor Saban. "COVID-19 Risk Compensation? Examining Vaccination Uptake among Recovered and Classification of Breakthrough Cases." Healthcare 11, no. 1 (2022): 58. http://dx.doi.org/10.3390/healthcare11010058.

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The study has two primary aims: the first is to examine the uptake of COVID-19 vaccination patterns among those previously infected, and the second is an evaluation of the period elapsed between the patient’s latest dose of the vaccine and the infection itself by demographic group. A retrospective study was conducted from 1 March 2020, to 31 May 2022, in Israel. The study found that among Israelis, vaccination uptake following infection is relatively low. When examining gender, one sees that the immunization rate among recovering females is higher than among men. Similarly, differences in upta

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Canadas, E. R., B. J. Duran, G. Machado, et al. "109 Pre-synchronization and reutilization of progesterone devices during a 6-day CO-Synch protocol for fixed-time artificial insemination in beef heifers." Reproduction, Fertility and Development 33, no. 2 (2021): 161. http://dx.doi.org/10.1071/rdv33n2ab109.

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Ovulatory response to the initial gonadotrophin-releasing hormone (GnRH) of the CO-Synch protocol is affected by circulating progesterone (P4) and follicle size. In addition, heifers that ovulate to the initial GnRH treatment have greater fertility after AI. Thus, this study determined the effect of (1) presynchronization (Presynch) before a 6-day CO-Synch protocol and (2) circulating [RCE1] (P4) on ovulatory response, oestrus expression, and pregnancies per AI (P/AI) in beef heifers. Yearling beef heifers (n=233) at three locations were randomly assigned in a 2×2 factorial design to the follo

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Canadas, E. R., B. J. Duran, G. Machado, et al. "109 Pre-synchronization and reutilization of progesterone devices during a 6-day CO-Synch protocol for fixed-time artificial insemination in beef heifers." Reproduction, Fertility and Development 33, no. 2 (2021): 161. http://dx.doi.org/10.1071/rdv33n2ab109.

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Ovulatory response to the initial gonadotrophin-releasing hormone (GnRH) of the CO-Synch protocol is affected by circulating progesterone (P4) and follicle size. In addition, heifers that ovulate to the initial GnRH treatment have greater fertility after AI. Thus, this study determined the effect of (1) presynchronization (Presynch) before a 6-day CO-Synch protocol and (2) circulating [RCE1] (P4) on ovulatory response, oestrus expression, and pregnancies per AI (P/AI) in beef heifers. Yearling beef heifers (n=233) at three locations were randomly assigned in a 2×2 factorial design to the follo

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Salykova, Valentina, and Lada Shtil'. "VARIETY STUDY OF SELECTED FORMS OF GOLDEN CURRANT (RIBES AUREUM PURSH.) BRED BY LRIHS IN CONDITIONS OF ALTAI OB REGION." Bulletin of KSAU, no. 9 (January 30, 2025): 53–59. https://doi.org/10.36718/1819-4036-2023-9-53-59.

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The purpose of the study is to conduct a comprehensive economic and biological assessment of selected forms of golden currant in the area of variety study for 2020–2022. Tasks: to study the phenological features of selected forms; to evaluate the yield and weight of berries; to take into account the components of productivity. The objects of study are 10 selected forms of locally selected golden currant (parental forms Levushka, Sibirskoe solnyshko, Otrada, 3593-98-12). The control variety is Levushka. Year of planting is 2018, autumn, scheme – 4 × 1 m. Productivity (by eye) was estimated in 3

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Malhi, Pritpal S., Gregg P. Adams, Reuben J. Mapletoft, and Jaswant Singh. "Oocyte developmental competence in a bovine model of reproductive aging." Reproduction 134, no. 2 (2007): 233–39. http://dx.doi.org/10.1530/rep-07-0021.

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The study was designed to test the hypothesis that aging in cattle is associated with reduced developmental competence of oocytes. The hypothesis was tested by comparing embryo production and pregnancy rates between 13- to 16-year-old cows (n = 6 in Year 1 and n = 9 in Year 2) and their 3- to 6-year-old young daughters (n = 8 in Year 1 and n = 9 in Year 2) after superovulation and transfer of embryos into an unrelated group of young recipients. Embryos were transferred into 2- to 5-year-old recipient cows (n = 99) as singletons (n = 45) or in pairs (n = 54 pairs). Embryo survival in recipients

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Oka, Hisao, Yuko Ito, Tomomi Goto, et al. "Survey of Residual Tetracycline Antibiotics and Sulfa Drugs in Kidneys of Diseased Animals in the Aichi Prefecture, Japan (1995–1999)." Journal of AOAC INTERNATIONAL 86, no. 3 (2003): 494–500. http://dx.doi.org/10.1093/jaoac/86.3.494.

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Abstract Animal kidneys were collected in order to survey the incidence of tetracycline (TC) antibiotics and sulfa (SA) drug residues in slaughtered animals that did not pass inspection for human consumption by the Japanese Food Sanitation Law and the Meat Inspection Law at the slaughterhouses in Aichi Prefecture, Japan, from April 1995 to March 2000. The kidneys were analyzed by AOAC Official Method 995.09 for TCs and our previously reported liquid chromatographic method for SAs. Among 292 animals (94 cattle and 198 pigs), 106 (36.6%) and 41 (14.0%) contained TCs and SAs, respectively, includ

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Matsuyama, Tomomi, Masanori Matsumoto, Ayami Isonishi, Shigeko Inokuma, and Yoshihiro Fujimura. "Analysis of ADAMTS13 and Its IgG-Autoantibodies in 170 Patients with Connective Tissue Disease-Associated Thrombotic Microangiopathy Indicates More Than 2 Types on Its Pathogenesis." Blood 110, no. 11 (2007): 1322. http://dx.doi.org/10.1182/blood.v110.11.1322.1322.

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Abstract Connective tissue disease (CTD) is sometimes complicated with thrombotic microangiopathy (TMA). Despite of the reports on several sporadic cases with acquired deficiency of ADAMTS13 activity (ADAMTS13:AC), it has been said that a majority of the patients with CTD-TMA have almost normal or slightly reduced levels of ADAMTS13:AC in their plasmas. But this has not been evaluated in a large population of such patients. As a nationwide referral center of TMA during the past 10 years, we were able to identify 783 patients with TMAs across Japan. Among these patients, 188 were categorized in

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Ludwig, Lynda M., Dorothee Weihrauch, Judy R. Kersten, Paul S. Pagel, and David C. Warltier. "Protein Kinase C Translocation and Src Protein Tyrosine Kinase Activation Mediate Isoflurane-induced Preconditioning In Vivo." Anesthesiology 100, no. 3 (2004): 532–39. http://dx.doi.org/10.1097/00000542-200403000-00011.

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Background The authors tested the hypotheses that protein kinase C (PKC)-specific isoform translocation and Src protein tyrosine kinase (PTK) activation play important roles in isoflurane-induced preconditioning in vivo. Methods Rats (n = 125) instrumented for measurement of hemodynamics underwent 30 min of coronary artery occlusion followed by 2 h of reperfusion and received 0.9% saline (control); PKC inhibitors chelerythrine (5 mg/kg), rottlerin (0.3 mg/kg), or PKC-epsilonV1-2 peptide (1 mg/kg); PTK inhibitors lavendustin A (1 mg/kg) or 4-amino-5-(4-methylphenyl)-7-(t-butyl)pyrazolo[3,4-d]py

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Chiguano-Tapia, Bryan, Elena Diaz, M. Angeles de la Rubia, and Angel F. Mohedano. "Co-Hydrothermal Carbonization of Swine Manure and Soybean Hulls: Synergistic Effects on the Potential Use of Hydrochar as a Biofuel and Soil Improver." Sustainability 17, no. 11 (2025): 5022. https://doi.org/10.3390/su17115022.

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The management through co-hydrothermal carbonization (co-HTC) of swine manure (SM) and soybean hulls (SH), a by-product of animal feeding, is established as a strategy for their material and/or energy recovery. The effect of hydrothermal carbonization (HTC) temperature (210–240 °C) and mass ratio (1:0, 1:1, 1:3, 0:1) on hydrochar characteristics revealed that an improved hydrochar (C (51–59%), HHV (21–24 MJ/kg), N (~2%), S (~0.3%), and ash (<9%)) is produced with respect to hydrochar obtained from individually treated wastes. Regarding biofuel characteristics, hydrochar obtained from the SM

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Nikiforova, E. M., N. V. Malyuzhinskaya, M. A. Chueva, V. V. Alferova, and E. N. Solov’ev. "Endoscopic and morphological features of chronic subatrophic gastroduodenitis in children." Kazan medical journal 96, no. 1 (2015): 42–45. http://dx.doi.org/10.17750/kmj2015-042.

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Aim. To identify the pecularities of clinical, functional features and morphological characteristics in children with subatrophic gastroduodenitis after eradication treatment.Methods. Gastrointestinal tract condition was examined in 26 children with subatrophic gastroduodenitis. Esophagogastroduodenoscopy with morphological analysis of biopsy specimens, esophageal pH test and urea breath test were performed.Results. 16 (60.7%) children reported low-grade pain, severe pain occurred in 3 (11.5%) patients, no abdominal pain was reported in 7 (27.6%) patients. A biopsy specimen was gained in 22 pa

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Claviez, Alexander, Hartmut Kabisch, Meinolf Suttorp, et al. "The Impact of Disease Status at Transplant and Time to First Relapse on Outcome in Children and Adolescents with Hodgkin’s Lymphoma Undergoing Autologous Stem Cell Transplantation." Blood 104, no. 11 (2004): 1878. http://dx.doi.org/10.1182/blood.v104.11.1878.1878.

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Abstract The prognosis of Hodgkin’s lymphoma (HL) in pediatric patients (pts) with current combined chemoradiotherapy regimens in general is excellent. Even those pts suffering from recurrent disease have a realistic chance for cure with salvage therapy regimens. 74 patients (<18 years at diagnosis; 69% male; 76% nodular sclerosis) mainly treated according to pediatric DAL or GPOH protocols received an autologous stem cell transplantation (ASCT) for recurrent or refractory disease between 1987 and 2003. 28 pts had progressive disease (PD, <3 months following the end of therapy), 34 had a

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Canadas, E. R., B. Duran, G. Machado, et al. "115 Presynchronization and reutilization of progesterone devices during a 6-day CO-Synch protocol for fixed-time artificial insemination in beef heifers." Reproduction, Fertility and Development 33, no. 2 (2021): 165. http://dx.doi.org/10.1071/rdv33n2ab115.

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Ovulatory response to the initial gonadotrophin-releasing hormone (GnRH) of the CO-Synch protocol is affected by circulating progesterone (P4) and follicle size. In addition, heifers that ovulate to initial GnRH treatment have greater fertility after AI. Thus, the aim of this study was to assess the effect of (1) presynchronization (Presynch) before a 6-day CO-Synch protocol and (2) P4 device reuse (new vs. second use) on ovulatory response, oestrous expression, and pregnancy per AI (P/AI) in beef heifers. Yearling beef heifers (n=233) were randomly assigned in a 2×2 factorial design to the fo

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Canadas, E. R., B. Duran, G. Machado, et al. "115 Presynchronization and reutilization of progesterone devices during a 6-day CO-Synch protocol for fixed-time artificial insemination in beef heifers." Reproduction, Fertility and Development 33, no. 2 (2021): 165. http://dx.doi.org/10.1071/rdv33n2ab115.

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Ovulatory response to the initial gonadotrophin-releasing hormone (GnRH) of the CO-Synch protocol is affected by circulating progesterone (P4) and follicle size. In addition, heifers that ovulate to initial GnRH treatment have greater fertility after AI. Thus, the aim of this study was to assess the effect of (1) presynchronization (Presynch) before a 6-day CO-Synch protocol and (2) P4 device reuse (new vs. second use) on ovulatory response, oestrous expression, and pregnancy per AI (P/AI) in beef heifers. Yearling beef heifers (n=233) were randomly assigned in a 2×2 factorial design to the fo

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Scenna, F. N., J. L. Edwards, and F. N. Schrick. "139PROSTAGLANDIN F2± COMPROMISES DEVELOPMENT OF PRE-IMPLANTATION BOVINE EMBRYOS DURING COMPACTION." Reproduction, Fertility and Development 16, no. 2 (2004): 191. http://dx.doi.org/10.1071/rdv16n1ab139.

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Several studies have implicated prostaglandin F2α (PGF) as a major embryotoxic factor during early embryonic development in cattle. Elevated uterine concentrations of PGF were negatively associated with embryo development, quality and pregnancy rates (Schrick FN et al. 1993 Biol. Reprod. 49, 617–621; Hockett ME et al. 1998 J. Anim. Sci. 76 (Suppl 1), 241 abst; Seals RC et al. 1998 Prostaglandins 56, 377–389). Moreover, addition of PGF to culture medium decreased hatching rates of compacted morulae (Scenna FN et al. 2002 Theriogenology 53, 512 abst) and decreased development of pre-compacted (1

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ادوارد جورج, ادوارد جورج. "تأثير المكملات الغذائية العشبية (® (MFAعلى التغذية، وترابط العليقة والوقاية من عدوى القناة الهضمية خلال فترة النمو في الاستزراع شبه المكثف لروبيان المحيط الهادئ أبيض الساق ليتوبينيس فانامي Litopenaeus vannamei (العائلة: Penaeidae)". journal of king abdulaziz university marine science 28, № 1 (2018): 27–41. http://dx.doi.org/10.4197/mar.28-1.3.

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تمت دراسة تأثير المكملات الغذائية العشبية شبه اللزجة (نكهات غذائية متعددة)، التي أُعدت بالطبخ من خليط من النباتات (نبات الخولجان Alpinia glanga، نبات Trikatu ، ونبات الاملج الشائع Emblica officinalis، ونبات الشمرة الشائعة Foeniculum vulgare، ونبات باكوبا منيرة Bacopa monnieri، ونبات العبعب المنوم Withania somnifera) على التغذية، وملزمة العلف، والنمو، والعوامل المتغيرة للدم، والوقاية من الأمراض لروبيان المحيط الهادئ ذي الساق البيضاء نوع Litopenaeus vannamei. تم إجراء الفحوصات الفيزيائية للروبيان في منصة الفحص لمراقبة الحالة الصحية، وكفاءة تلقيم الأعلاف، ووقت التجفيف، وخصائص الأعلاف. كما تم تسجي

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Steen, R. W. J. "The effect of supplementing silage-based diets with soya bean and fish meals for finishing beef cattle." Animal Science 46, no. 1 (1988): 43–51. http://dx.doi.org/10.1017/s0003356100003093.

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ABSTRACTTwo experiments have been carried out to examine the effects on the intake and performance of finishing beef cattle of supplementing grass silages (perennial ryegrass) of medium and high digestibility (MD and HD respectively) with either extracted soya-bean meal or fish meal. In each experiment, the two silages were supplemented with (1) barley (107 g crude protein (CP) per kg dry matter (DM)), (2) a mixture of barley and soya-bean meal (187 g CP per kg DM) and (3) a mixture of barley and fish meal (182 g CP per kg DM) in a 2 × 3 factorial design. The MD silages were supplemented with

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Tsuji, H., R. Nakashima, T. Sasai, et al. "POS0142 THE ASSOCIATION OF AUTOANTIBODIES WITH CLINICAL MANIFESTATIONS AND LONG-TERM REMISSIONS IN COMPARISON WITH JUVENILE- AND ADULT-ONSET IDIOPATHIC INFLAMMATORY MYOPATHIES." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 291–92. http://dx.doi.org/10.1136/annrheumdis-2023-eular.323.

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BackgroundThe associations of myositis-specific autoantibodies (MSAs) and myositis-associated autoantibodies (MAAs) with clinical features and remission in idiopathic inflammatory myopathy (IIM) are different between those of juvenile-onset (JIIM) and adult-onset.ObjectivesSince the associations in JIIM had not been fully elucidated, we analyzed them comparing that in adults using clinical information and autoantibodies.MethodsA total of 320 cases of IIMs (juvenile-onset, 2004-2021, n=34; adult-onset, 2018-2021, n=286) with a history of attendance at our hospital were retrospectively analyzed

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Lorentino, Francesca, Myriam Labopin, Fabio Ciceri, et al. "Haploidentical T-Repleted Stem Cell Transplantation (SCT) Has Comparable Survival to 10/10 and 9/10 Unrelated SCT in Poor-Cytogenetics Risk Acute Myeloid Leukemia in First Complete Remission: A Study on Behalf of the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT)." Blood 130, Suppl_1 (2017): 852. http://dx.doi.org/10.1182/blood.v130.suppl_1.852.852.

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Abstract Background: Allogeneic stem cell transplantation (SCT) is the most powerful therapy to prevent relapse in poor-cytogenetics risk acute myeloid leukemia (poorAML) patients (pts) in first complete remission (CR1). For pts who lack a matched related donor (MRD), SCT from an unrelated (UD) or alternative donor is indicated. Pts with poorAML and thus at high risk of relapse can theoretically benefit the most from SCT from haploidentical donors (HaploSCT), which is an attractive option as the time required to find a well-matched UD could be inacceptable. Several recent reports show comparab

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Chen, John J., Eoin P. Flanagan, M. Tariq Bhatti, et al. "Steroid-sparing maintenance immunotherapy for MOG-IgG associated disorder." Neurology 95, no. 2 (2020): e111-e120. http://dx.doi.org/10.1212/wnl.0000000000009758.

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ObjectiveMyelin oligodendrocyte glycoprotein–immunoglobulin G (MOG-IgG) associated disorder (MOGAD) often manifests with recurrent CNS demyelinating attacks. The optimal treatment for reducing relapses is unknown. To help determine the efficacy of long-term immunotherapy in preventing relapse in patients with MOGAD, we conducted a multicenter retrospective study to determine the rate of relapses on various treatments.MethodsWe determined the frequency of relapses in patients receiving various forms of long-term immunotherapy for MOGAD. Inclusion criteria were history of ≥1 CNS demyelinating at

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Jackson, Edwin K., Dongmei Cheng, Zaichuan Mi, Jonathan D. Verrier, Keri Janesko-Feldman, and Patrick M. Kochanek. "Role of A1 receptors in renal sympathetic neurotransmission in the mouse kidney." American Journal of Physiology-Renal Physiology 303, no. 7 (2012): F1000—F1005. http://dx.doi.org/10.1152/ajprenal.00363.2012.

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A1 receptors may participate in renal sympathetic neurotransmission by enhancing the postjunctional effects of norepinephrine. The purpose of this study was to test this concept using A1 receptor knockout (A1AR−/−) mice. In isolated kidneys from nontransgenic mice perfused with Tyrode's solution at a constant rate, renal sympathetic nerve stimulation (RSNS) increased ( P < 0.0001) renal venous perfusate levels of inosine (adenosine metabolite) from 23.9 ± 3.7 to 32.7 ± 5.1, 68.2 ± 12.4, and 94.0 ± 14.3 ng/ml at 3, 5, and 7 Hz, respectively ( n = 28), suggesting frequency-dependent productio

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Zagorodnikova, Ksenia A. "The impact of oxidative stress on the neurotoxic effect of acetaminophen." Butlerov Communications 59, no. 9 (2019): 106–9. http://dx.doi.org/10.37952/roi-jbc-01/19-59-9-106.

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Paracetamol (acetaminophen, APAP) is a commonly-used antipyretic and analgesic. However, there have been reports indicating possible link between its use in pregnancy and impaired neuropsychic development in children. A number of prospective studies of the possible negative effect of acetaminophen on the development of a child after his mother took this drug during pregnancy, as well as the results of studies on glioma cells and neurons in murine cortex, may indicate presence of the neurotoxic effect of acetaminophen. It is currently unclear if paracetamol itself being pharmacologically active

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Ning, Y. M., P. Arlen, J. Gulley, et al. "A phase II trial of thalidomide, bevacizumab, and docetaxel in patients (pts) with metastatic androgen-independent prostate cancer (AIPC)." Journal of Clinical Oncology 25, no. 18_suppl (2007): 5114. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.5114.

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5114 Background: Angiogenesis plays a vital role in the progression of prostate cancer. Antiangiogenic agents thalidomide (T) and bevacizumab (Bv) may enhance docetaxel (Doc) activity in metastatic AIPC. However, T and Bv have different antiangiogenic mechanisms. Since tumor angiogenesis is a complex interplay of multiple angiogenic factors, we reasoned that combination of mechanistically different antiangiogenic agents T and Bv with Doc might be associated with an adequately high and durable PSA response to merit further study. Methods: Pts are required to have progressive metastatic AIPC and

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Li, Ka Hou Christien, Rachel Wing Chuen Lai, Yimei Du, et al. "Effects of exercise on heart rate variability by time-domain, frequency-domain and non-linear analyses in equine athletes." F1000Research 8 (February 4, 2019): 147. http://dx.doi.org/10.12688/f1000research.17997.1.

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Background: Heart rate variability (HRV) is an intrinsic property that reflects autonomic balance and has been shown to be predictive of all-cause and cardiovascular mortality. It can be altered by physiological states such as exercise or pathological conditions. However, there are only a handful of studies on HRV in horses. The aim of this study is to compare HRV parameters before and during exercise in horses. Methods: Time-domain, frequency-domain and non-linear analyses were applied to quantify time series data on RR intervals before and during exercise in horses (n=7). Results: Exercise i

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Hafez, Abdulwahab M. "First Evaluation of Field Evolved Resistance to Commonly Used Insecticides in House Fly Populations from Saudi Arabian Dairy Farms." Insects 12, no. 12 (2021): 1120. http://dx.doi.org/10.3390/insects12121120.

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The house fly, Musca domestica L. (Diptera: Muscidae), is one of the major vectors of several pathogens that affect humans and animals. We evaluated the toxicity of eight insecticides commonly used for house fly control using five field populations collected from dairies in Riyadh, Saudi Arabia. Among the five tested pyrethroids, non to moderate resistance was found in adults of both sexes compared to a susceptible strain. Resistance ratios ranged from 0.5- to 7-fold for alpha-cypermethrin, 2- to 21-fold for deltamethrin, 4- to 19-fold for bifenthrin, 1- to 9-fold for cyfluthrin, and 1- to 8-f

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Schwarze, Jens Jürgen, Sophie Schumann, Silvio Brandt, Olaf Dirsch, and Bernhard Rosengarten. "Thrombus age does not differentiate between cardiogenic and atherosclerotic strokes." BMJ Neurology Open 6, no. 2 (2024): e000724. http://dx.doi.org/10.1136/bmjno-2024-000724.

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ObjectiveInterventional stroke therapy made thrombi available for histological analysis. Unfortunately, simple composition aspects such as erythrocyte versus fibrin/platelet rich did not allow a feasible allocation to thrombi’s cardiac or carotid origin. Since the mentioned criteria represent characteristics of thrombus age, we used established histological criteria for determining thrombus age in patients who had an atherosclerotic (TOAST (Trial of Org 10172 in Acute stroke Treatment) 1) stroke versus patients who had a cardioembolic (TOAST 2) stroke.MethodsWe assessed prospectively data from

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Craike, Melinda J., Kylie Mosely, Jessica L. Browne, Frans Pouwer, and Jane Speight. "Associations Between Physical Activity and Depressive Symptoms by Weight Status Among Adults With Type 2 Diabetes: Results From Diabetes MILES–Australia." Journal of Physical Activity and Health 14, no. 3 (2017): 195–202. http://dx.doi.org/10.1123/jpah.2016-0196.

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Background:To examine associations between physical activity (PA) and depressive symptoms among adults with type 2 diabetes mellitus (Type 2 DM), and whether associations varied according to weight status.Methods:Diabetes MILES–Australia is a national survey of adults with diabetes, focused on behavioral and psychosocial issues. Data from 705 respondents with Type 2 DM were analyzed, including: demographic and clinical characteristics, PA (IPAQ-SF), depressive symptoms (PHQ-9), and BMI (self-reported height and weight). Data analysis was performed using ANCOVA.Results:Respondents were aged 59

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