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1
Novianti, Teni. "KANDUNGAN BETAKAROTEN DARI MIKROALGA Chlorella vulgaris YANG DIKULTUR DENGAN PERLAKUAN SUMBER CAHAYA DAN KEPADATAN AWAL INOKULUM (KAI) YANG BERBEDA." Mangifera Edu 4, no. 1 (2019): 46–61. http://dx.doi.org/10.31943/mangiferaedu.v4i1.37.
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Chlorella vulgaris termasuk salah satu jenis mikroalga hijau bersel tunggal (unicellular) yang diameter selnya berkisar antara 2-8 mikron. Pigmen pada Chlorella vulgaris selain berfungsi sebagai aktivitas antioksidan tetapi juga memiliki efek perlindungan terhadap degenerasi retina dan memperkuat sistem kekebalan tubuh. Penelitian ini bertujuan untuk mengetahui kandungan Betakaroten pada Mikroalga Chlorella vulgaris yang dikultur dengan perlakuan sumber cahaya dan kepadatan awal inokulum yang berbeda. Metode penelitian yang digunakan adalah metode eksperimental, sedangkan rancangan penelitian yang digunakan adalah Rancangan Acak Lengkap Faktorial terdiri atas 6 perlakuan dan 3 kali ulangan. Perlakuannya adalah sumber cahaya neon (32 watt) yang ditambahkan dengan LED Merah, LED Hijau dan LED Biru masing-masing 16 watt dengan KAI C.vulgaris yang dikultivasi yaitu 10x104 sel/ml dan 100x104 sel/ml. Hasil penelitian menunjukkan Kandungan Pigmen β-karoten tertinggi yaitu 721,572 mg/l pada LED biru dengan Kepadatan Awal Inokulum (KAI) 100x104 sel/ml.
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Hapsari, Indri, S. Yudha Patria, and IL Gamayanti. "Hubungan Hipertirotropinemia Terhadap Tingkat dan Aspek Kecerdasan Anak TK di Desa Seloharjo Kecamatan Pundong, Bantul, Yogyakarta." Sari Pediatri 15, no. 6 (2016): 420. http://dx.doi.org/10.14238/sp15.6.2014.420-6.
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Latar belakang. Hipertirotropinemia (peningkatan TSH) menunjukkan adanya insufisiensi saturasi reseptor T3 di otak dan potensial berisiko defisiensi dalam perkembangan kecerdasan. Semakin muda anak mengalami defisiensi hormon tiroid maka semakin berat terhadap gangguan kecerdasan. Hormon tiroid dirangsang sekresinya oleh TSH (Thyroid stimulating hormone). Hipertirotropinemia digunakan sebagai penapis pertama dalam deteksi gangguan tiroid.Tujuan. Mengetahui adanya hubungan hipertirotropinemia dengan tingkat dan aspek kecerdasan anak taman kanak-kanak (TK) di Desa Seloharjo, Kecamatan Pundong, Bantul, Yogyakarta.Metode. Rancangan penelitian potong lintang dengan jumlah subjek 51 anak dari dua TK di Desa Seloharjo selama bulan Desember 2010. Desa Seloharjo dipilih karena termasuk daerah endemik GAKI, sumber data lengkap, dan bisa dijangkau. Penilaian dilakukan terhadap kadar tetes darah TSH (dengan ELISA) dan tingkat kecerdasan serta aspek (dengan Stanford-Binet). Analisis dengan uji kai-kuadrat dan uji regresi logistik.Hasil. Terdapat 39,2% responden termasuk hipertirotropinemia dengan rerata TSH 5,59 μUI/mL. Intelligency Quotient poin di bawah rata-rata 25,5% dengan rerata 96,8 poin. Anak hipertirotropinemia dengan IQ di bawah rata-rata 6 orang (30%) dengan rerata TSH 7,63 μUI/ml (kenaikan 1,38 kali) dan rerata IQ 81 poin. Tidak didapatkan hubungan bermakna antara kadar TSH dengan tingkat kecerdasan (p=0,553, RP=1,469, 95%IK 0,4-5,254) dan enam aspek kecerdasan (p>0,05). Hasil uji regresi logistik menunjukkan variabel lain tidak memengaruhi tingkat kecerdasan, sedangkan untuk aspek penalaran aritmatika terbukti dipengaruhi oleh adanya anggota keluarga yang gondok (p=0,045, RP 8,448, IK95% 1,050-67,977).Kesimpulan. Hipertirotropinemia tidak terbukti memengaruhi tingkat dan aspek kecerdasan anak TK.
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Ardika, Kadek, Muhdiat Muhdiat, and I. Nyoman Restiada. "PENGGUNAAN JENIS PAKAN BERBEDA PADA KULTUR ROTIFER (Brachionus rotundiformis)." Buletin Teknik Litkayasa Akuakultur 11, no. 1 (2016): 57. http://dx.doi.org/10.15578/blta.11.1.2013.57-60.
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Keberhasilan kultur rotifer akan sangat tergantung dari jenis dan mutu pakan yang diberikan. Beberapa jenis fitoplankton yang dapat digunakan sebagai pakan rotifer adalah Nannochloropsis oculata dan Tetraselmis sp. Kegiatan ini bertujuan untuk mengetahui pengaruh penggunaan jenis pakan berbeda terhadap pertumbuhan populasi rotifer, yaitu jenis fitoplankton Nannochloropsis oculata dan Tetraselmis tetrahele, dengan dosis pemberian pakan sebagai berikut: Nannochloropsis oculata 250.000 sel/ind./hari, sedangkan Tetraselmis tetrahele 25.000 sel/ind./hari diberikan dua kal i sehari , kepadatan awal rotifer sebanyak 20 ind./mL, wadah kultur menggunakan bak fiber glas volume 30 liter sebanyak 6 buah dengan menerapkan tiga ulangan pada masing-masing perlakuan. Hasil pengamatan pertumbuhan rotifer selama 4 hari, menunjukkan bahwa kepadatan populasi rotifer tertinggi diperoleh pada pemberian jenis pakan Tetraselmis tetrahele dengan kepadatan 436 ind./mL, sedangkan pada pemberian jenis pakan Nannochloropsis oculata hanya 168 ind./mL.
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Mattson, C., K. Wikström, C. Sterky, and G. Pohl. "Synergism between Tissue-Type Plasminogen Activator and a Genetically Engineered Variant Lacking the Finger Domain, the Growth Factor Domain and the First Kringle Domain." Thrombosis and Haemostasis 65, no. 03 (1991): 286–90. http://dx.doi.org/10.1055/s-0038-1648136.
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SummaryA modified variant of human tissue-type plasminogen activator (t-PA) lacking the finger domain (F), the growth factor domain (G) and the first kringle domain (K1), has an extended plasma half-life in vivo, compared to that of t-PA. When the variant (denoted K2P) was tested in vitro for its ability to lyse human plasma clots we found that the activity was characterized by a time lag phase and a sigmoidal dose-response curve. However, an attenuation of the lag phase in vitro was observed both when K2P was mixed with t-PA in a w/w ratio of 4 : 1 and when K2P was allowed to lyse a clot that had been pre-exposed to t-PA i.e. submitted to a limited plasmic digestion. Dosis that in vitro caused 50% lysis within 6 h were calculated from individual dose-response curves and were for K2P, t-PA and K2P/t-PA (4 : 1 w/w) 540 ng/ml, 360 ng/ml and 310 ng/ml, respectively. These results indicated a synergistic effect between K2P and t-PA. However, the data from individual dose-response curves showed that the effect of the K2P/t-PA mixture never was better than that of t-PA alone, and the synergistic effect in vitro is therefore considered to be of limited use. The thrombolytic activity in vivo was evaluated in a rabbit jugular vein thrombus model. Despite the lag phase observed in vitro, K2P was approximately 3 times as effective as t-PA in vivo (bolus injection). The thrombolytic effect of K2P was further potentiated when it was administred together with a small amount of t-PA (4 : 1 w/w). This potentiation in vivo was, in contrast to the effect in vitro, a useful synergistic effect as the dose-response curve for the K2P/t-PA mixture was steeper than that of t-PA and K2P alone. Doses that caused 50% lysis within 3 h were for t-PA, K2P and K2P/t-PA 1.28 mg/kg, 0.56 mg/kg and 0.35 mg/kg, respectively.
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Novianti, Teni, Muhammad Zainuri, and Ita Widowati. "Aktivitas Antioksidan dan Identifikasi Golongan Senyawa Aktif Ekstrak Kasar Mikroalga Chlorella Vulgaris Yang Dikultivasi Berdasarkan Sumber Cahaya Yang Berbeda." Barakuda 45: Jurnal Ilmu Perikanan dan Kelautan 1, no. 2 (2019): 72–87. http://dx.doi.org/10.47685/barakuda45.v1i2.44.
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Chlorella vulgaris termasuk salah satu jenis fitoplankton dalam kelas Chlorophyceae (alga hijau) yang dapat dimanfaatkan sebagai suplemen maupun sumber obat alami yang berpotensi sebagai antioksidan. Untuk memaksimalkan pertumbuhan dan senyawa bioaktif C.vulgaris yang dapat menghasilkan biomassa dan metabolit sekunder yang memiliki aktivitas antioksidan membutuhkan sumber cahaya buatan terbaik. Tujuan dari penelitian ini adalah untuk mengetahui aktivitas antioksidan dan golongan senyawa aktif ekstrak kasar mikroalga C.vulgaris yang dikultivasi pada sumber cahaya yang berbeda. Metode penelitian yang digunakan adalah metode eksperimental, sedangkan rancangan penelitian yang digunakan adalah Rancangan Acak Lengkap Faktorial terdiri atas 6 perlakuan dan 3 kali ulangan. Perlakuannya adalah sumber cahaya neon (32 watt) yang ditambahkan dengan LED Merah, LED Hijau dan LED Biru masing-masing 16 watt dengan KAI C.vulgaris yang dikultivasi yaitu 10x104 sel/ml dan 100x104 sel/ml. Hasil penelitian menunjukan penggunaan sumber cahaya neon yang ditambahkan LED berwarna merah, hijau dan biru dengan kepadatan awal inokulum 100x104 sel/ml memperoleh hasil pertumbuhan C.vulgaris tertinggi pada sumber cahaya LED merah sebesar 2057,7x104sel/ml. Sedangkan sumber cahaya neon yang ditambahkan LED biru menghasilkan aktivitas antioksidan terbaik dengan nilai IC50 38,900 (antioksidan sangat kuat) dan memiliki komponen bioaktif alkaloid, steroid, saponin, flavonoid dan kuinon.
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Sage, Eva Katharina, Marco M. E. Vogel, Sabrina Dewes, et al. "Stereotactic Body Radiotherapy (SBRT) für die Behandlung von Knochenmetastasen beim oligometastasierten Prostatakarzinom." TumorDiagnostik & Therapie 41, no. 06 (2020): 393–98. http://dx.doi.org/10.1055/a-1202-9478.
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Zusammenfassung Hintergrund Die lokale Strahlentherapie von Metastasen bei Prostatakarzinompatienten in der oligometastasierten Situation hat in den letzten Jahren an Bedeutung gewonnen. Um die Wirkung auf das Outcome weiter zu evaluieren, haben wir oligometastasierte Prostatakarzinompatienten, die eine stereotaktische Strahlentherapie (SBRT) von Knochenmetastasen erhielten, untersucht. Patienten und Methodik Es wurden 24 Patienten mit insgesamt 30 Knochenmetastasen eingeschlossen und das Ansprechen auf die SBRT (biochemisch und bildgebend) sowie das progressionsfreie Überleben und das Zeitintervall bis zum Beginn einer antihormonellen Therapie (aHT) untersucht. Ergebnisse Das mittlere Follow-up-Intervall nach Abschluss der SBRT lag bei 32,7 Monaten (1,4–84 Monate). Die SBRT wurde ohne das Auftreten von Akut- oder Spät-Nebenwirkungen sehr gut vertragen. Bei 16 Patienten kam es zu einem Abfall des PSA-Wertes von im Mittel 4,58 ng/ml (0,05–50,25 ng/ml) vor der SBRT auf 1,19 ng/ml (0,01–8,85 ng/ml) nach Abschluss der SBRT. Das mittlere biochemische progressionsfreie Überleben dieser Patienten betrug 17,6 Monate (0,7–85,0 Monate). 6 Patienten erhielten bereits vor der SBRT oder parallel dazu eine aHT. Bei 10 Patienten wurde die aHT nach einem mittleren Intervall von 20,6 Monaten (1,8–85,0 Monate) nach Abschluss der SBRT initiiert, während weitere 6 Patienten keine aHT während des gesamten Beobachtungszeitraums erhielten. Bei 18 der 30 Metastasen konnte im Bereich der SBRT im PSMA-PET eine Abnahme der PSMA-Expression im Sinne eines partiellen funktionellen Ansprechens beobachtet werden, während bei 5 Patienten nach SBRT eine gleichbleibende PSMA-Überexpression bestand und bei 7 Patienten keine PSMA-Bildgebung vorlag. Bei 17 Patienten kam es im Mittel nach 16,2 Monaten (1,6–40,6 Monate) bildgebend zum Progress der Fernmetastasierung, während 3 Patienten ein Lokalrezidiv in der Prostataloge zeigten. Zusammenfassung Die SBRT von Knochenmetastasen bei oligometastasierten Prostatakarzinompatienten stellt eine effektive und gut verträgliche Therapie dar, durch die eine hohe lokale Kontrolle im Bereich der Metastasen sowie eine Verzögerung des Beginns oder der Eskalation einer Systemtherapie erzielt werden kann. Jedoch zeigt die hohe Rate an Progression der Fernmetastasierung die Wichtigkeit der richtigen Patientenselektion auf und ggf. die Notwendigkeit der Kombination mit einer aHT.
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Sage, Eva Katharina, Marco M. E. Vogel, Sabrina Dewes, et al. "Stereotactic Body Radiotherapy (SBRT) für die Behandlung von Knochenmetastasen beim oligometastasierten Prostatakarzinom." Aktuelle Urologie 51, no. 03 (2020): 265–70. http://dx.doi.org/10.1055/a-1140-5646.
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Zusammenfassung Hintergrund Die lokale Strahlentherapie von Metastasen bei Prostatakarzinompatienten in der oligometastasierten Situation hat in den letzten Jahren an Bedeutung gewonnen. Um die Wirkung auf das Outcome weiter zu evaluieren haben wir oligometastasierte Prostatakarzinompatienten, die eine stereotaktische Strahlentherapie (SBRT) von Knochenmetastasen erhielten, untersucht. Patienten und Methodik Es wurden 24 Patienten mit insgesamt 30 Knochenmetastasen eingeschlossen und das Ansprechen auf die SBRT (biochemisch und bildgebend) sowie das progressionsfreie Überleben und das Zeitintervall bis zum Beginn einer antihormonellen Therapie (aHT) untersucht. Ergebnisse Das mittlere Follow-Up-Intervall nach Abschluss der SBRT lag bei 32,7 Monaten (1,4 – 84 Monate). Die SBRT wurde ohne das Auftreten von Akut- oder Spät-Nebenwirkungen sehr gut vertragen. Bei 16 Patienten kam es zu einem Abfall des PSA-Wertes von im Mittel 4,58 ng/ml (0,05 – 50,25 ng/ml) vor der SBRT auf 1,19 ng/ml (0,01 – 8,85 ng/ml) nach Abschluss der SBRT. Das mittlere biochemische progressionsfreie Überleben dieser Patienten betrug 17,6 Monate (0,7 – 85,0 Monate). 6 Patienten erhielten bereits vor der SBRT oder parallel dazu eine aHT. Bei 10 Patienten wurde die aHT nach einem mittleren Intervall von 20,6 Monaten (1,8 – 85,0 Monate) nach Abschluss der SBRT initiiert, während weitere 6 Patienten keine aHT während des gesamten Beobachtungszeitraumes erhielten. Bei 18 der 30 Metastasen konnte im Bereich der SBRT im PSMA-PET eine Abnahme der PSMA-Expression im Sinne eines partiellen funktionellen Ansprechens beobachtet werden, während bei 5 Patienten nach SBRT eine gleichbleibende PSMA-Überexpression bestand und bei 7 Patienten keine PSMA-Bildgebung vorlag. Bei 17 Patienten kam es im Mittel nach 16,2 Monaten (1,6 – 40,6 Monate) bildgebend zum Progress der Fernmetastasierung, während 3 Patienten ein Lokalrezidiv in der Prostataloge zeigten. Zusammenfassung Die SBRT von Knochenmetastasen bei oligometastasierten Prostatakarzinompatienten stellt eine effektive und gut verträgliche Therapie dar, durch die eine hohe lokale Kontrolle im Bereich der Metastasen sowie eine zeitliche Verzögerung des Beginns oder der Eskalation einer Systemtherapie erzielt werden kann. Jedoch zeigt die hohe Rate an Progression der Fernmetastasierung die Wichtigkeit der richtigen Patientenselektion auf und ggf. die Notwendigkeit der Kombination mit einer aHT.
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Ramadhani, Rachmat, Dwi Sandri, and Jaka Darma Jaya. "OPTIMASI PRODUKSI BIOBRIKET DARI KULIT BUAH KARET." Jurnal Teknologi Agro-Industri 2, no. 2 (2016): 19. http://dx.doi.org/10.34128/jtai.v2i2.15.
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Biobriket merupakan energi alternatif pengganti bahan bakar yang dihasilkan dari bahan-bahan organik atau biomasa yang kurang termanfaatkan. Beberapa jenis limbah biomasa memiliki potensi yang cukup besar seperti limbah kayu, sekam padi, jerami, ampas tebu, cangkang sawit. Penelitian ini bertujuan untuk mengoptimasi produksi biobriket dari kulit buah karet dengan parameter pengujian meliputi analisis kadar air, nilai kalor, lama bakar dan laju bakar. Pembuatan biobriket ini berbahan baku dari kulit buah karet yang dimulai dari proses pengarangan kemudian digiling dan dicampur dengan perekat dan cetak lalu dijemur. Adapun perekat yang digunakan adalah tepung tapioka dengan konsentrasi perekat 3%, 4%, 5%, dan 6% pada pembuatan biobriket dan air yang digunakan sebanyak 250 ml dan 375 ml terhadap masing-masing konsentrasi. Hasil penelitian menunjukan bahwa briket dengan perlakuan menggunakan perekat 4% yang dilarutkan dengan 250 ml air mendekati SNI briket arang. Hasil tersebut menunjukan kadar air 6,12%, nilai kalor 6351,58 kal/gr, lama bakar 43 menit dan laju bakarnya 0,28 gr/menit. Melihat dari hasil penelitian ini bahwa kulit buah karet dapat dijadikan salah satu bahan baku alternatif dalam pembuatan biobriket.
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Haas, Elisabeth Maria, Elias Volkmer, and Riccardo E. Giunta. "Pilotstudie über die Wirkung und den Nutzen von autologen Fettgewebstransplantaten bei Rhizarthrose verglichen mit einer Kortisoninjektion – 3 Monatsergebnisse." Handchirurgie · Mikrochirurgie · Plastische Chirurgie 49, no. 05 (2017): 288–96. http://dx.doi.org/10.1055/s-0043-120114.
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ZusammenfassungZusammenfassung Hintergrund/Ziel Erste Ergebnisse deuten darauf hin, dass eine intraartikuläre autologe Fetttransplantation bei Rhizarthrose nützlich sein kann. Diese prospektive, nicht randomisierte Pilotstudie untersucht diese neue Methode hinsichtlich ihres klinischen Ergebnisses im Vergleich mit einer intraartikulären Kortikosteroidinjektion. Patienten und Methoden 17 Frauen und 7 Männer mit einem Durchschnittsalter von 63,3 (47–75) Jahren mit symptomatischer Rhizarthrose wurden in die Studie eingeschlossen. Bei 12 Patienten erfolgte nach transumbillikaler Fettabsaugung von 10 ml Bauchfett unter radiologischer Kontrolle die Injektion von 1–1,5 ml Fettgewebe in das Daumensattelgelenk. Zuvor wurde das Fett unter Verwendung von zwei Luer-Lock-Spritzen homogenisiert, jedoch nicht zentrifugiert. Postoperativ erfolgte eine Ruhigstellung mittels Handgelenksschiene unter Einschluss des Daumens für 1 Woche. Die Patienten der Kortison-Kontrollgruppe erhielten unter sterilen Bedingungen eine intraartikuläre Injektion von 10 mg (1 ml) Triamcinolon®. Es erfolgte keine Ruhigstellung. Präoperativ und 2, 6 und 12 Wochen postoperativ wurden der QuickDASH und der Michigan-Hand-Questionnaire (MHQ) erhoben, die Schmerzen anhand der visuellen Analogskala (VAS) bestimmt und Grob- sowie Griffkraft gemessen. Ergebnisse Sowohl in der Kortison- als auch in der Eigenfett-Gruppe zeigte sich nach zwei Wochen ein signifikanter Rückgang des Belastungsschmerzes. Beide Maßnahmen hatten keinen signifikanten Einfluss auf die Kraft. Die Auswertungen der Lebensqualität mittels QuickDASH und MHQ nach Kortisonbehandlung zeigte zunächst eine Verbesserung der Lebensqualität, welche allerdings nach der 6. Woche unter das Vorniveau abfiel. Nach Eigenfetttransplantation kam es zu einer kontinuierlichen Zunahme der Lebensqualität. Schlussfolgerung Im Gegensatz zur Therapie mit Kortisoninjektion konnte im 3-Monats-Nachuntersuchungszeitraum eine anhaltende Schmerzreduktion in der Fettinjektionsgruppe erzielt werden, wohingegen eine Kortisoninjektion nur zu einer kurzfristigen, im Mittel etwa 6 Wochen anhaltenden Reduktion des Schmerzes führte. Eine längerfristige Nachuntersuchung muss nun zeigen, wie nachhaltig der Effekt der autologen Fetttransplantation bei Rhizarthrose ist.
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Almanfaluthy, Mohammad Rizal, Moch Bintoro, and Prasodjo Soedomo. "Pengaruh Konsentrasi dan Interval Waktu Pemberian Larutan Nutrisi Bahan Organik (BP-1) Terhadap Pertumbuhan dan Hasil Bibit Bawang Merah (Allium ascalonicum L.)." Agriprima, Journal of Applied Agricultural Sciences 3, no. 2 (2019): 51–60. http://dx.doi.org/10.25047/agriprima.v3i2.194.
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Penelitian pengaruh konsentrasi dan interval waktu pemberian larutan nutrisi bahan organik Biopras (Bp-1) terhadap pertumbuhan dan hasil bibit bawang merah (Allium ascalonicum L.) bertujuan mengetahui pengaruh konsentrasi larutan Bp-1 yang terbaik pada pertumbuhan dan hasil bibit bawang merah (Allium ascalonicum L.). Penelitian produksi bibit bawang merah di laksanakan pada tanggal 11 September 2018 di Dusun Dongkol, Desa Sukasari Kaler, Kec. Argapura, Kab. Majalengka, Jawa Barat. Penelitian ini menggunakan Rancangan Acak Petak Terbagi (Splitplot) secara faktorial. Petak utama interval waktu penyemprotan meliputi I1= interval waktu penyemprotan Bp-1 3 hari sekali, I2= interval waktu penyemprotan Bp-1 6 hari sekali, I3= interval waktu penyemprotan Bp-1 9 hari sekali. Anak petak konsentrasi Bp-1 meliputi B0 = Tanpa Di semprot larutan Bp-1, B1 = Di semprot larutan Bp-1 konsentrasi 1 ml per liter air, B2 = Di semprot larutan Bp-1 konsentrasi 2 ml per liter air, B3 = Di semprot larutan Bp-1 konsentrasi 3 ml per liter air, B4 = Di semprot larutan Bp-1 konsentrasi 4 ml per liter air. Data pengamatan pada setiap parameter dianalisis menggunakan analisis rumus F (ANOVA) diikuti dengan uji lanjut BNT dan DMRT taraf 5%. Hasil penelitian menunjukkan bahwa perlakuan interval waktu penyemprotan 3 hari sekali (I1) berpengaruh nyata pada parameter jumlah umbi per rumpun (11,51), berat basah umbi per rumpun (128,20 g), dan berat kering umbi per rumpun (80,68 g). Sedangkan konsentrasi larutan Bp-1 3 ml per liter air (B3) berpengaruh nyata pada parameter tinggi tanaman umur 14 hari (16,88 cm) dan 28 hari setelah tanam (28,17 cm), jumlah daun umur 14 hari (9,78) dan 28 hari setelah tanam (28,37), tinggi batang semu umur 42 hari setelah tanam (6,77 cm), jumlah umbi per rumpun (11,19) dan berat basah umbi per rumpun (130, 46 g).
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Bernhardt, A. W., K. Failing, G. Schuler, and B. Hoffmann. "Profile von Estron, Estronsulfat und Progesteron während der Trächtigkeit beim Esel (Equus asinus)." Tierärztliche Praxis Ausgabe G: Großtiere / Nutztiere 42, no. 01 (2014): 32–39. http://dx.doi.org/10.1055/s-0038-1623202.
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Zusammenfassung Ziel: Erhalt weiterführender Daten zur endokrinen Kontrolle der Gravidität beim Esel und von Referenzwerten zur hormonellen Graviditätsdiagnostik. Material und Methodik: In monatlichen Abständen gewonnene Blutproben stammten von 23 Eselstuten mit normal verlaufenden Einlingsgraviditäten. Weiterhin wurden Proben von sechs Stuten mit klinischen Auffälligkeiten gewonnen. Die Bestimmung von Progesteron (P4), Gesamt-Estron (GE), freiem und konjugiertem Estron (E und ES) erfolgte mittels radioimmunologischer Verfahren. Ergebnisse: Die Trächtigkeitsdauer betrug im Mittel 372 ± 16 Tage; sie war bei Groß- und Normaleseln mit 375,9 ± 5,7 bzw. 385,8 ± 20,7 Tagen länger als bei Minieseln (357,4 ± 5,7 Tage, p < 0,05) und wies eine negative Korrelation (p = 0,043) zum Alter der Stute auf. Die P4-Werte schwankten in der 2.–5. Trächtigkeitswoche (TW) zwischen ca. 12 und 35 ng/ml, wonach sich bei acht Stuten die Anbildung der Copora lutea auxiliaria (CLA) durch einen steilen Anstieg der P4-Konzentration auf ca. 40–110 ng/ml in der 12.–17. TW zeigte. Der nachfolgende Abfall führte zu Werten zwischen 5 und 16 ng/ml bis zur ca. 46. Woche. Bei den meisten Stuten kam es zu einem geringen Anstieg zur Geburt. Die GE-Konzentrationen lagen bis zur 6. TW bei < 1 ng/ml, stiegen danach auf ca. 600–2700 ng/ml in der Mitte der Gravidität und fielen auf ca. 1–20 ng/ml in den letzten beiden TW ab. Der Verlauf von E und ES war mit p < 0,0001 korreliert, die E-Konzentration war bis zu 1000-mal niedriger als die von ES. Aus den Hormonverläufen er gaben sich keine eindeutigen Hinweise auf die beobachteten klinischen Auffälligkeiten. Schlussfolgerung: Der Verlauf der P4-Konzentration entspricht weitgehend der Situation beim Pferd. Bei den Östrogenen fehlt der beim Pferd charakteristische Anstieg von ES in Verbindung mit der Anbildung der CLA, ansonsten ergibt sich eine weitgehende Übereinstimmung. Rassespezifische Unterschiede zeigten sich nur bezüglich der Trächtigkeitsdauer. Klinische Relevanz: Die hormonelle Graviditätsdiagnostik beim Esel konnte auf eine solide Basis gestellt werden. Eine GE Konzentration > 5 ng/ml lässt mit hoher Wahrscheinlichkeit auf eine vorliegende Gravidität schließen. Ein hormonelles Graviditätsmonitoring als präventive Maßnahme ist derzeit noch nicht möglich.
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Vongsak, Boonyadist, Sunan Jaisamut, Kanokporn Gonsap, and Porntip Parmontree. "Optimization of Maclura cochinchinensis Extract as a Cosmeceutical Component for Antioxidant and Anti-Tyrosinase Activities." Key Engineering Materials 859 (August 2020): 188–93. http://dx.doi.org/10.4028/www.scientific.net/kem.859.188.
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Maclura cochinchinensis Corner or Kae Lae in Thai belongs to the Moraceae family. The plant is found in Southeast Asian countries and used in traditional medicine as a tonic agent to treat chronic fever and skin infections. Previous studies have demonstrated that plants in Moraceae family, such as Morus alba and Artocarpus lakoocha are rich source of antioxidant and anti-tyrosinase agents. Thus, the current study aimed at comparing different solvent extracts (50% ethanol, 80% ethanol, methanol by ultrasound and water decoction) of M. cochinchinensis heartwood for their antioxidant and anti-tyrosinase activities. Total phenolic content, 2, 2-diphenyl-1-picrylhydrazyl (DPPH), 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activity, ferric reducing antioxidant power (FRAP) and anti-lipid peroxidation assays were performed to compare the antioxidant activity, whereas, Dopachrome method was performed for anti-tyrosinase activity. The results demonstrated that 80% ethanol and methanol extracts had better antioxidant activities based on EC50 value of DPPH (9.96±0.21 and 9.50±0.46 μg/mL, respectively), ABTS (6.54±0.13 and 6.58±0.69 μg/mL, respectively), anti-lipid peroxidation (228.31±2.03 and 231.43±1.41 μg/mL, respectively), and anti-tyrosinase (7.60±0.29 and 7.91±0.41 μg/mL, respectively) assays. Further, 80% ethanol extract was selected to evaluate the bioactive compound using bioactivity-guided isolation. Oxyresveratrol identified as bioactive compound, exhibited higher activities than the positive controls (quercetin and kojic acid). In conclusion, 80% ethanolic M. cochinchinensis heartwood extract obtained using the ultrasound technique exhibited strong antioxidant and anti-tyrosinase effects and can be used as a potential active ingredient for cosmeceutical products. Oxyresveratrol could be used as bioactive marker for quality control of the extract and products.
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Ovčarenko, Sergej, Viktorija Danilova, and Violeta Kalnicka. "Changes in the level of interleukin-4 and interleukin-6 in response to angioprotective therapy in children with severe birth asphyxia." Medicinski casopis 54, no. 1 (2020): 18–22. http://dx.doi.org/10.5937/mckg54-25065.
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Objective. The development of clinical and laboratory criteria for diagnosis of systemic inflammatory response significantly expanded the use of this concept in clinical practice. The correlation between the levels of antiinflammatory and pro-inflammatory cytokines is an important aspect in regulation of systemic inflammatory response. Treatment of systemic inflammatory response includes three main links: effect on the levels of endotoxin, cytokines and the state of endothelium. Currently there is no unified approach to the solution of this problem, which determines the relevance of the topic. The aim of the research was to study the efficacy of the deproteinized hemodialysate from the newborn calf blood in systemic inflammatory response in newborns with severe asphyxia at birth. Methods. The study involved examination of 16 newborns with severe asphyxia at birth, who received a drug as part of standard therapy from the first day of the disease at a dose of 0.5 ml/kg. The study implied a follow-up assessment of interleukin-4 and interleukin-6 levels. Sign test and Wilcoxon test were used for paired samples; Kolmogorov-Smirnov and Mann-Whitney tests were used for non-paired samples. To investigate the influence of the independent variable on the dependent variable we used Kruskal-Wallis and median tests as nonparametric analogs of the variance analysis. Results. Deproteinized hemodialysate derived from the newborn calf blood is a vasoprotector and is a combination of a number of physiologically active ingredients. They stimulate oxygen utilization by tissues in hypoxic conditions, enhancing glucose transport through biological membranes, intensifying intracellular adenosine triphosphate synthesis, and increasing the proportion of aerobic glycolysis. Conclusion. Administration of deproteinized hemodialysate from the newborn calf blood in the treatment of systemic inflammatory response in newborns with severe asphyxia at birth exerts influence on biochemical pattern of systemic inflammatory response by reducing inflammation and reducing synthesis of cytokines.
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Elser, H., S. Haufe, R. Ziegler, P. Georgi, and J. Pfeilschifter. "Einfluß prätherapeutischer Variablen auf die Wirkung einer standardisierten 131J-Therapie mit 150 Gray beim Morbus Basedow." Nuklearmedizin 36, no. 03 (1997): 81–86. http://dx.doi.org/10.1055/s-0038-1629865.
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Zusammenfassung Ziel: Bei 61 Patienten mit einem Morbus Basedow haben wir den Einfluß prätherapeutischer Variablen auf die Funktion und das Volumen der Schilddrüse ein Jahr nach einer 131J-Therapie mit 150 Gray untersucht. Methoden: FT3, FT4, und TSH wurden vor Therapie und eineinhalb, 3, 6 und 12 Monate nach Therapie gemessen. Das Schilddrüsenvolumen wurde vor Therapie und ein Jahr nach Therapie sonographisch und szin-tigraphisch bestimmt. Ergebnisse: Ein Jahr nach Therapie waren 30% der Patienten latent oder manifest hyperthyreot, 24% euthyreot, und 46% latent oder manifest hypothyreot. Lebensalter und Ausgangsvolumen der Schilddrüse waren die Hauptprädiktoren der posttherapeutischen Schilddrüsenfunktion. Der Anteil an persistierenden Hyperthyreosen war bei älteren Patienten mit einem Schilddrüsenvolumen größer 50 ml mit über 70% besonders hoch. Bei fast allen Patienten kam es zu einer deutlichen Verkleinerung der Schilddrüse. Ausgangsvolumen und Lebensalter waren auch hier die Hauptprädiktoren der posttherapeutischen Schilddrüsengröße. Bei allen Patienten jünger als 50 Jahre kam es sogar unabhängig von der Ausgangsgröße zu einer Normalisierung des Schilddrüsenvolumens. Schlußfolgerung: Eine Radiojodtherapie mit 150 Gray führt bei den meisten Patienten mit einem Morbus Basedow zu einer deutlichen Verkleinerung der Schilddrüse. Alter und initiales Volumen haben einen wesentlichen Einfluß auf die Funktion und Größe der Schilddrüse nach Therapie und sollten bei der Dosisfestlegung berücksichtigt werden.
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Kang, Hyun Hee, Aung Htay Naing, and Chang Kil Kim. "Protoplast Isolation and Shoot Regeneration from Protoplast-Derived Callus of Petunia hybrida Cv. Mirage Rose." Biology 9, no. 8 (2020): 228. http://dx.doi.org/10.3390/biology9080228.
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Despite the increasing use of protoplasts in plant biotechnology research, shoot regeneration from protoplasts remains challenging. In this study, we investigated the factors involved in protoplast isolation, callus induction, and shoot regeneration in Petunia hybrida cv. Mirage Rose. The following conditions were found to be most optimal for protoplast yield and viability: 0.6 M mannitol, 2.0% cellulase, and 6 h digestion time. A plating density of 10 × 104 protoplasts/mL under osmoticum condition (0.58 M mannitol) showed high microcolony viability in liquid culture. The Kao and Michayluk medium was found to be appropriate for callus proliferation from microcalli under a 16-h light photoperiod. Calli cultured in Murashige and Skoog medium containing 1.0 mg/L 6-benzylaminopurine and 0.2 mg/L 3-indole butyric acid showed the highest shoot regeneration frequency and number of shoots obtained per explant. Random amplification of polymorphic DNA analysis showed that the protoplast-derived shoots exhibited the same banding patterns as those of donor plants. Collectively, these findings can contribute to solving problems encountered in protoplast isolation and shoot regeneration in other petunia cultivars and related species. As the protocol developed by us is highly reproducible, it can be applied in biotechnology research on P. hybrida cv. Mirage Rose.
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Rau, Franco. "Erster Entwurf und experimentelle Praxis." MedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung, Lernsituationen m. Metaphern & W (July 4, 2020): 304–470. http://dx.doi.org/10.21240/mpaed/diss.fr/2020.07.04.x.
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Der vierte Teil der Arbeit präsentiert den Entwurf von Lernsituationen zur integrativen Medienbildung im Rahmen von Seminaren der erziehungswissenschaftlichen Studienanteile (Kap. 6) sowie die systematische Dokumentation der Praxiserprobung und deren wissenschaftliche Analyse (Kap. 7). Zu Beginn wird das Ziel verfolgt, die im Rahmen des Entwicklungsprojektes getroffenen didaktischen Entscheidungen nachvollziehbar darzustellen und zu begründen. Auf Basis der vorausgegangenen Kapitel werden die getroffenen Gestaltungs- und Entwicklungsentscheidungen auf den hochschuldidaktischen Handlungsebenen der «(Lehr)Veranstaltungen» sowie der «(Lern)Situationen» (Wildt 2002) formuliert. In Anlehnung an Tulodziecki et al. (2014) umfasst der Entwurf die Aspekte: Zielvorstellungen (Kap. 6.2), Annahmen zu den Voraussetzungen der Lernenden (Kap. 6.3), Annahmen zu potenziell relevanten Lern- und Lehrhandlungen (Kap. 6.4, Kap. 6.5) sowie einen Entwurf von konzeptbezogenen Seminaren (Kap. 6.6). Mit der Dokumentation der Praxiserprobung wird ein systematischer Einblick in die Realisierung des Entwurfs aus der Perspektive des Lehrenden gegeben (Kap. 7.2). Zur wissenschaftlichen Untersuchung bzw. empirischen Analyse erfolgt aufbauend auf den Ausführungen zum forschungsmethodischen Design (Kap. 3) zunächst eine Konkretisierung der spezifischen Erhebungssituationen sowie der vorgenommenen Anpassungen der Auswertungsmethoden (Kap. 7.3). Die Ergebnisse der durchgeführten Erhebungen und Analysen werden vorgestellt (Kap. 7.4) und bilden die Grundlage für die im nächsten Kapitel folgende Diskussion und Weiterentwicklung des Konzeptes (Kap. 8).
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Tzortzaki, Eleni G., Dayna Glass, Min Yang, et al. "Gender- and Age-dependent Changes in Kidney Androgen Protein mRNA Expression in a Knockout Mouse Model for Nephrolithiasis." Journal of Histochemistry & Cytochemistry 50, no. 12 (2002): 1663–69. http://dx.doi.org/10.1177/002215540205001211.
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Kidney androgen-regulated protein (Kap) is the most abundant protein in the mouse kidney, but its function is unknown. We previously observed a significant decrease in Kap mRNA expression in whole kidney tissue from male mice with adenine phosphoribosyltransferase (APRT) deficiency and 2,8-dihydroxyadenine (DHA) nephrolithiasis. The disease phenotype is more severe in male mice and is age-dependent. To identify the cellular basis for differential Kap expression, we used in situ hybridization (ISH) and reverse transcription-polymerase chain reaction ISH (RT-PCR ISH) to identify the cell types expressing this mRNA in paraffin-embedded kidney sections. In 1-month-old wild-type male mice, Kap was detected primarily in S3 proximal tubule segments, but expression was very low in female mice. In 1-month-old APRT-deficient male mice, Kap expression was decreased significantly and was undetectable in female mice. Kap mRNA was not detected in 3- or 6-month-old mice using our standard ISH protocol, but we observed intense cytoplasmic staining in S3 proximal tubules in wild-type male mice of these age groups using an improved RT-PCR ISH procedure. Our studies demonstrate age-, gender-, and APRT genotype-dependent changes in Kap mRNA expression in mouse kidney. Kap expression is under multihormonal control, and hormonal changes in DHA-induced nephrolithiasis may account for the decreased Kap expression in APRT-deficient mice.
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Wardini, Benari Saras, and Lenny Christina Nawangsari. "The Influence of Employer Branding and Organizational Culture on Employee Engagement with Motivation as Mediators on the Millennials Generation at KAP TSFBR." European Journal of Business and Management Research 6, no. 4 (2021): 388–93. http://dx.doi.org/10.24018/ejbmr.2021.6.4.1007.
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This study aims to analyze the effect of Employer Branding and Organizational Culture on Employee Engagement with Motivation as a Mediator for the millennials generation working at KAP TSFBR. Respondents in this study are 138 employees who were born between 1980 – 1995. This research used Descriptive Statistics with Structural Equation Modeling (SEM) analysis methods with variance-based multivariate statistical techniques using PLS.
 The results of the study conclude that: 1) Employer branding has a positive and significant effect on employee engagement of millennials generation working at KAP TSFBR, 2) Employer branding has a positive and significant impact on the motivation of millennials working at KAP TSFBR, 3) Organizational culture has a positive and significant impact on employees' engagement of millennials working at KAP TSFBR, 4) Organizational culture has a positive and significant effect on the motivation of millennials working at KAP TSFBR, 5) Motivation has a positive and significant effect on millennials working at KAP TSFBR, 6 ) Employer branding has a positive and significant effect on employee engagement through motivation as a mediator for millennials working at TSFBR KAP, and 7) Organizational culture has a positive and significant effect on employee engagement through motivation as a mediator for millennials working at KAP TSFBR.
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Agustina, Rina, Fadila Wirawan, Arini A. Sadariskar, et al. "Associations of Knowledge, Attitude, and Practices toward Anemia with Anemia Prevalence and Height-for-Age Z-Score among Indonesian Adolescent Girls." Food and Nutrition Bulletin 42, no. 1_suppl (2021): S92—S108. http://dx.doi.org/10.1177/03795721211011136.
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Background: Crucial gaps persist in knowledge, attitude, and practice (KAP) of adolescent girls that affect anemia and linear growth failure. Objective: To understand the role of KAP as a risk factor of anemia and linear growth problem in adolescent girls. Methods: We conducted a cross-sectional survey of 335 adolescent girls selected by clustered random sampling. The KAP questionnaire had 18 variables consisting of 9 knowledge, 3 attitude, and 6 practice components. Twelve variables addressed nutrition, dietary diversity, and health environments related to both anemia and stunting. The questionnaire was adapted from the 2014 Food and Agriculture Organization nutrition-related KAP guidelines for anemia. Dietary practice was evaluated from 2-day 24-hour recalls and a semi-quantitative food-frequency questionnaire. Associations between KAP and anemia, and height-for-age z-score (HAZ), were analyzed using multivariate logistic and linear regression models, respectively. Results: The mean hemoglobin (Hb) level was 119.7 g/L, with 44% of the adolescent girls being anemic (Hb < 120 g/L) and mean height was 151.0 cm with 25% being stunted (HAZ < −2 standard deviation [SD]). The median KAP score was 7 and ranged from 3 to 10. Low to moderate KAP scores were not significantly associated with being anemic (adjusted odds ratio [AOR] = 1.26; P = .43), however 1-point KAP score increment was associated with an increase of HAZ by 0.037 SD ( P = .012). Conclusions: The KAP related to diet and healthy environments was not associated with anemia prevalence, but was positively associated with increased HAZ among adolescent girls. Strategy to reduce anemia risk in this population should combine KAP improvement with other known effective nutrition interventions.
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Hutapea, Hotma. "Gambaran Kasus Mutasi Terkait Resistensi Antiretroviral pada orang dengan HIV-AIDS (ODHA) di Tiga Kabupaten/Kota di Provinsi Papua." Buletin Penelitian Kesehatan 46, no. 3 (2018): 199–206. http://dx.doi.org/10.22435/bpk.v46i3.902.
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Antiretroviral (ARV) therapy has been found effective to decrease HIV-1 infected cases, however increase the resistances due to nucleotide mutation. The mutation causes virus to be resistant to ARV, making the therapy is no longer effective. The ARV therapy District Nabire, Jayapura, and Jayawijaya was Reverse Transcriptase Inhibitor (RTI). The goal of this study was to obtain the data of mutation associated to viral resistance to ARV RTI and protease inhibitor group. Plasma samples were obtained from 252 subjects purposively in HIV/AIDS population from corresponding Care, Support, and Therapy clinic. The genotyping, measurement of CD4 and viral load were performed to all samples. DNA analysis was performed by genotyping method. Among 252 samples, 89 samples (35.32%) had CD4 count <350 sel/ul. Twenty three samples (8.73%) had viral load >10.000 copies/mL. There were 15 (5,95%) samples were identified as mutant related to RTI resistance, and none for protease. The most frequent mutation motive was M184V/I, 12 samples (80,00%). This data provided important information about the continuous need of ARV therapy monitoring to suppress transmission drug resistance. 
 
 Abstrak 
 Penemuan antiretroviral (ARV) secara signifikan telah menjadi bagian penting dalam penanggulangan HIV/AIDS. Terapi ARV dilakukan untuk menurunkan kasus HIV-1, namun dapat menyebabkan resistensi virus terhadap ARV tersebut. Data prevalensi HIV-1 resisten ARV pada Orang Dengan HIV/AIDS (ODHA) di Papua, khususnya Kabupaten Nabire, Kab./Kota Jayapura, dan Kab. Jayawijaya belum tersedia. Tujuan penelitian ini adalah untuk mendapatkan data prevalensi mutasi terkait resistensi virus terhadap ARV golongan penghambat rtase dan protease. Sebanyak 84 responden yang sudah diterapi minimal 6 bulan diambil secara purposive dari setiap lokasi penelitian. Genotyping, pemeriksaan nilai CD4 dan viral load dilakukan terhadap semua sampel. Analisis DNA dilakukan dengan metode genotyping. Dari 252 sampel, sebanyak 89 responden (35,32%) memiliki nilai CD4 <350 sel/ul darah. Sebanyak 23 responden (8,73%) memiliki nilai viral load >10.000 salinan/mL. Sebanyak 15 sampel (5,95%) teridentifikasi mengalami mutasi pada DNA target ARV golongan penghambat rtase, dan tidak ditemukan mutasi terkait resistensi pada gen protease. Motif mutasi yang paling banyak adalah M184V/I, yaitu sebanyak 12 sampel (80,00%). Penelitian ini mengindikasikan bahwa pemantauan terapi ARV secara berkesinambungan tetap diperlukan untuk menekan penulan HIV resisten ARV.
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SETYO-BUDI, UNTUNG, SUDJINDRO SUDJINDRO, and R. D. PURWATI. "VARIASI KETAHANAN GENOTIPE KENAF (Hibiscus cannabinus L.) TERHADAP NEMATODA PURU AKAR (Meloidogyne incognita)." Jurnal Penelitian Tanaman Industri 15, no. 2 (2020): 60. http://dx.doi.org/10.21082/jlittri.v15n2.2009.60-65.
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<p>ABSTRAK</p><p>Nematoda puru akar (Meloidogyne sp.) merupakan penyakit yangtergolong penting dan banyak menyerang pertanaman kenaf di lahanpengembangan maupun pembenihan, sehingga banyak menimbulkankerugian bagi petani karena terjadi penurunan produktivitasnya. Tanamankenaf (H. cannabinus) umumnya tidak tahan nematoda, namun kerabatdekat kenaf dari jenis liar seperti H. radiatus (radiatus) diketahuimengandung gen ketahanan terhadap nematoda. Persilangan inter spesifikantara kenaf dan radiatus yang beda spesies, diharapkan akan dapatmentransfer gen ketahanan dari radiatus ke kenaf, sehingga diperolehvarietas unggul kenaf yang tahan nematoda. Tujuan penelitian ini adalahuntuk mengetahui variabilitas genetik sifat ketahanan tanaman kenafterhadap serangan M. incognita pada F1 dibandingkan dengan keduatetuanya. Kegiatan persilangan interspesifik antara kenaf (H. cannabinus)dan radiatus (H. radiatus) dilakukan di KP. Karangploso Malang padaTahun 2002, sedangkan uji ketahanan nematoda puru akar (M. incognita)terhadap keturunan dan kedua tetuanya dilaksanakan di Desa Kendalrejo,Kabupaten Blitar pada bulan Februari s/d Agustus 2003. Pengujianketahanan di lapang dilakukan menggunakan metode baris tanpa ulanganpada jarak tanam 20 x 20 cm, dengan perlakuan terdiri dari lima set hasilpersilangan dan kedua tetuanya yakni 20 populasi F1, 20 populasi P1 dan20 populasi P2, dengan masing-masing populasi 20 tanaman. Hasil ujitanah di laboratorium menunjukkan bahwa rata-rata kandungan larva M.incognita (sebagai populasi awal) adalah sebesar 96 ekor/100 ml tanahdan dikategorikan sangat tinggi. Sedangkan hasil identifikasi sidik pantat(berdasarkan perenial patternnya) terhadap larva betina dewasa diketahuibahwa jenis nematoda di lokasi penelitian adalah dari spesies Meloidogyneincognita. Pengamatan dan perhitungan larva M. incognita dilakukan diLaboratarium Hama dan Penyakit Balittas, Malang. Pengamatan dilakukanterhadap jumlah puru akar per tanaman, kerusakan akar tanaman, danpopulasi larva M. incognita dalam tanah sebagai faktor R (R = reproduksilarva). Untuk menggolong-golongkan tingkat ketahanan terhadap M.incognita digunakan metode Zeck melalui indeks kerusakan akar. Darihasil penelitian menunjukkan bahwa, semua keturunan F1 dari 5persilangan interspesifik antara KR 6 x Kal II, KR 11 x Kal II, KR 12 xKal II, Hc G-1 x Kal II, dan Hc G-51 x Kal II tidak ada yang tahanterhadap serangan M. incognita. Nilai ketahanan genotipe F1 terletak diantara tetua jantan (Kal II/ radiatus) yang tahan dan tetua betina (kenaf)yang sangat rentan.</p><p>Kata kunci : Hibiscus cannabinus L., interspesifik, variabilitas genetik,ketahanan, Meloidogyne incognita</p><p>ABSTRACT</p><p>Resistance variability of kenaf (Hibiscus cannabinus L.)genotypes to root-knot nematode (Meloidogyne incognitaL.)Root Knot Nematode (Meloidogyne incognita) is an importantdisease on kenaf plantation in the development area and its nursery. Thiscondition generates reduce of productivity and loss of farmers’ income.Kenaf plants are generally not resistant to nematode infestation, so theyneed resistant gene from other species (H. radiatus) to be transfered to H.cannabinus by interspecific hybridization. The objective of this researchwas to obtain genetic variability of kenaf resistance to Meloidogyneincognita attact. Interspecific hybridization between H. cannabinus and H.radiatus was conducted at KP Karangploso, Malang in 2002. Meanwhile,evaluation of F1 lines and their parents to M. incognita resistance wasconducted at Kendalrejo, Blitar on February to August 2003. In this area,the type of soil is medium fertile-light-sandy soil containing high densitiesof root-knot nematode larvae. Five sets of F1 resulted from hybridizationbetween H. canabinus and H. radiatus and their parents were planted in arow method without replication. Subsequently, these seeds were used asthe materials in this study. The observation and evaluation of these larvaewas performed at the Phytopathology Laboratory of the IndonesianTobacco and Fiber Crops Research Institute, Malang. The preliminaryresult showed that the average of the initial population was 96 larvae per100 ml of soil, which is categorized as a very high larvae content.Furthermore, the identification to the adult female larvae (perennial patternmethod) showed that the root-knot nematode found in the location ischaracterized as M. incognita. Parameters observed were total number ofgall per plant, degree of root damage, and populations of M. incognitalarvae in the soil as a R-factor (R = larvae reproduction). The degree ofresistance to M. incognita are analyzed according to Zeck method usingroot damage index. Results of this research are : all F1 from fiveinterspesific hybridization between KR 6 x Kal II, KR 11 x Kal II, KR 12x Kal II, Hc G-1 x Kal II, and Hc G-51 x Kal II are still more sucseptiblecompared to their male parent (Kal II) which is resistant to root-knotnematode.</p><p>Key words : Hibiscus cannabinus L., interspecific, genetic variability,resistance, Meloidogyne incognita</p>
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Maurer, Elisabeth, Sabine Wächter, Max Albers, Katharina Holzer, and Detlef Bartsch. "Die transaxilläre roboterassistierte Thyreoidektomie – Ergebnisse und Akzeptanz einer neuen Operationsmethode." Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie 143, no. 04 (2018): 353–60. http://dx.doi.org/10.1055/a-0647-7168.
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Zusammenfassung Hintergrund In der Schilddrüsenchirurgie sind in den letzten Jahren vermehrt alternative Zugänge evaluiert und teilweise etabliert worden, um dem vermeintlich zunehmenden kosmetischen Anspruch der Patienten mit Vermeidung einer sichtbaren Narbe am Hals zu entsprechen. Wir berichten hier über unsere Erfahrungen mit der transaxillären roboterassistierten Thyreoidektomie (TRAT). Methoden Im Rahmen einer prospektiven Beobachtungsstudie wurde die TRAT zunächst Patienten mit Indikation zur einseitigen Schilddrüsenoperation bei benigner Struma mit einem Lappenvolumen bis 40 ml nach ausführlicher Aufklärung angeboten. Die Akzeptanz der Methode und deren operativer Ergebnisse, insbesondere die Operationszeit, sowie intra- und postoperative Komplikationen wurden ausgewertet. Zudem wurde die Zufriedenheit der Patienten mit dem kosmetischen Ergebnis 8 – 12 Wochen nach der Operation erfragt. Ergebnisse Von Januar 2013 bis Januar 2018 wurde 151 Patienten eine TRAT angeboten, wovon sich 65 (43,0%) für diese Operationsmethode entschieden. Bei diesen 65 Patienten erfolgten 51 Hemithyreoidektomien, 6 Isthmusresektionen und 8 Dunhill-Operationen. Die durchschnittliche Operationszeit betrug 121,5 Minuten (Spannweite 83 – 221) für die Isthmusresektionen, 165,0 Minuten (Spannweite 100 – 300) für die Hemithyreoidektomien und 259 Minuten (Spannweite 197 – 320) für die Dunhill-Operationen. Die Rate an Recurrensparesen betrug 8,2% (6 von 73 „nerves at risk“), wovon diese bei 2 Patienten (2,7%) nach 6 Monaten persistierten. Ein postoperativer Hypoparathyreoidismus oder Nachblutungen kamen nicht vor, ebenso keine Tracheal-, Ösophagus- oder Gefäßverletzungen. Bei 9 Patienten (13,8%) kam es zu passageren Hautparästhesien über dem Zugangsweg, 2 der ersten 5 (3,1%) Patienten erlitten passagere Armplexusparesen. 93% der Patienten bewerteten das kosmetische Ergebnis als „gut“ oder „sehr gut“, die Weiterempfehlungsrate lag ebenfalls bei 93%. Schlussfolgerung Die TRAT ist vor allem bei einseitigen Befunden sicher und in akzeptabler Zeit durchführbar. Die TRAT kommt in Deutschland aufgrund der geringen Akzeptanz durch die Patienten, der hohen Kosten der Methodik ohne Refinanzierung und die Limitationen bei großer Struma nur für ein sehr selektioniertes Patientengut infrage.
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Irawati, Irawati, Erita Hayati, and Ashabul Anhar. "Pengaruh Pemberian Mikoriza dan Konsentrasi Pupuk Organik Cair Limbah Kulit Pisang terhadap Pertumbuhan Bibit Kopi Arabika (Coffea arabica L.) Varietas Ateng Keumala." Jurnal Ilmiah Mahasiswa Pertanian 4, no. 2 (2020): 21–30. http://dx.doi.org/10.17969/jimfp.v4i2.11015.
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Abstrak. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian mikoriza dan konsentrasi pupuk organik cair dari limbah kulit pisang terhadap pertumbuhan bibit kopi arabika varietas Ateng Keumala. Penelitian ini dilaksanakan di lahan perkebunan kopi milik petani di kampung Beranun Kecamatan Bandar Kabupaten Bener Meriah dari bulan Juni sampai September 2018. Penelitian ini menggunakan Rancangan Acak Kelompok (RAK) pola faktorial 2 x 4 dengan 3 ulangan, sehingga terdapat 24 satuan percobaan dan uji F yang signifikan dilanjutkan dengan uji beda nyata jujur taraf 5% . Faktor pertama adalah pemberian mikoriza dengan 2 taraf yaitu kontrol (M0) dan 10 g/tanaman (M1). Faktor kedua adalah konsentrasi pupuk organik cair limbah kulit pisang dengan 4 taraf yaitu kontrol, 2%, 4% dan 6% ml/L. Parameter yang diamati adalah tinggi tanaman, jumlah daun, diameter pangkal batang, panjang akar, berat berangkasan basah, dan berat berangkasan kering. Hasil penelitian menunjukan bahwa, pemberian mikoriza tidak berpengaruh nyata terhadap semua parameter yang diamati. Konsentrasi pupuk organik cair berpengaruh nyata terhadap parameter tinggi tanaman umur 60 HSPT, namun tidak berpengaruh nyata terhadap parameter tinggi tanaman, jumlah daun, diameter pangkal batang, panjang akar, berat berangkasan basah, dan berat berangkasan kering. Perlakuan terbaik di jumpai pada konsentrasi pupuk organik cair limbah kulit pisang 4% ml/L. Terdapat interaksi yang nyata pada jumlah daun umur 30 HSPT.The Influence Of Mycorrhiza and Concentration Liquid Organic fertilizer BananaSkin Waste On Growth Coffea Breed Arabika (Coffea arabica L.) VARIETAS ATENG KEUMALA arabica L.) Variety Of Ateng KeumalaAbstract. PenelitianResearch ini this bertujuan u ntuk aims for mengetahui knowing pengaruh influence pemberian gift mikoriza mycorrhiza dan and konsentrasi concentration pupuk fertilizer organik organic cair liquid dari from limbah waste kulit skin pisang banana terhadap to pertumbuhan growth bibit kopi arabika arabica coffee seeds varietas varieties Ateng Ateng Keumala . Keumala. Penelitian Research ini this dil aksana kan on account, right di in lahan land perkebunan kopi milik coffee plantation owned petani the farmer di in kampung village Beranun Brave Kecamatan Bandar Kabupaten District of Bandar District Bener Right Meriah dari bulan Festive of the month Juni June sampai September 2018. until September 2018. Penelitian ini menggunakan Rancangan This research uses Design Acak Random Kelompok (RAK) pola Group (RAK) pattern faktorial 2 x 4 dengan 3 ulangan , sehingga terdapat 24 satuan percobaan dan dilanjutkan dengan uji beda nyata jujur taraf 5 % pada uji F yang signifikan. factorial 2 x 4 with 3 replications, so that there are 24 experimental units and continued with an honest real difference test of 5 % level in a significant F test. F aktor Factor pertama a dalah first is it pemberian gift mikoriza mycorrhiza dengan 2 taraf with 2 levels yaitu that is kontrol (M 0 ) dan 10 g/ tanaman (M 1 ) . control (M0) and 10 g /plant (M1). Faktor kedua adalah konsentrasi The second factor is concentration pupuk fertilizer organi k cair organic liquid limbah waste kulit skin pisang banana dengan 4 taraf with 4 levels yaitu kontrol , 20% namely control, 2%, 40%, dan 60% ml/l., 4% and 6% ml/L. P arameter yang diamati adalah tinggi Parameter observed is high tanaman , jumlah plant height, amount daun , diameter pangkal batang , leaf, stem diameter, root lengthakar , berat, berangkasan basah , danwet weightberangkasan, and dryberat weight berangkasan. Hasil Results penelitian research menunjukan showing bahwa , pemberian mikoriza tidak berpengaruh nyata terhadap semua parameter yang diamati. that , the administration of mycorrhizae did not significantly affect all observed parameters. Konsentrasi pupuk organik cair berpengaruh nyata terhadap parameter tinggi tanaman umur 60 HSPT, namun tidak berpengaruh nyata terhadap parameter tinggi tanaman, jumlah daun, diameter pangkal batang, panjang akar, berat berangkasan basah, dan berat berangkasan kering. The concentration of liquid organic fertilizer had a significant effect on the parameters of plant age 60 diafter day transflanting, but did not significantly affect the parameters of plant height, number of leaves, stem base diameter, root length, wet weight, and dry weight. Perlakuan terbaik di jumpai pada konsentrasi pupuk organik cair limbah kulit pisang 40 % ml/l ( P 2 ) . The best treatment was found at a concentration of 4% ml / L of banana peel liquid organic fertilizer . There were significant interactions on the number of leaves aged 30 diafter day transflanting.
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Mahmud, G., K. Igbal, Y. Hasebe, and T. Nakasa. "Knowledge and practice (KAP) about maternal health and nutrition." International Journal of Gynecology & Obstetrics 70 (2000): C63. http://dx.doi.org/10.1016/s0020-7292(00)80505-6.
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Andrassi-Darida, Monika, Christine Mais, Knut Stieger, and Birgit Lorenz. "Fluoreszenzangiografieassistiertes Management von Rezidiven bei aggressiver posteriorer Frühgeborenenretinopathie (APROP) nach intravitrealer Monotherapie mit 0,312 mg Bevacizumab." Klinische Monatsblätter für Augenheilkunde 237, no. 12 (2019): 1468–76. http://dx.doi.org/10.1055/a-1012-1999.
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Zusammenfassung Hintergrund Bei aggressiver posteriorer Frühgeborenenretinopathie (APROP) können Rezidive nach intravitrealer Injektion von Bevacizumab (IVB) trotz erfolgreicher Aktivitätskontrolle des Akutstadiums auftreten und erfordern daher langfristige Kontrolluntersuchungen bei Extremfrühgeborenen. Als Rezidiv wird das Wiederauftreten von Pluszeichen und Leckage (mit oder ohne Proliferation) posterior, an und anterior der Vaskularisationsgrenze definiert. Methoden RetCam-Weitwinkelfotografien und Fluoreszenzangiografien erfolgten bei Therapiebeginn mit IVB (Bevacizumab 0,312 mg in 0,025 ml pro Auge), vor jeder weiteren Therapie (IVB, Laser- oder Kryokoagulation, Pars-plana-Vitrektomie) sowie am Therapieende. Es wurde das Bildmaterial von 18 Augen/9 Extremfrühgeborenen mit APROP die zwischen 08/2008 und 12/2017 behandelt wurden (GA 21 – 27 Wochen, GG 430 – 890 g) ausgewertet. Ergebnisse Mit einer einmaligen Injektion konnte nur bei 4 Augen/2 Kindern (22%) ein langfristiger Therapieerfolg erreicht werden. In 2 Augen/2 Kindern (11%) wurde bei nicht ausreichendem Therapieeffekt eine 2. und 3. Injektion innerhalb von 2 Wochen durchgeführt. Bis zu 3 Injektionen zusammen mit einer Laserkoagulation waren in 12 Augen/6 Kindern (67%) erforderlich, um eine vollständige Rückbildung der ROP-Aktivität zu erreichen. In 6 Augen/3 Kindern (33%) konnte erst mit der Laserkoagulation eine Rückbildung der Leckage an der ursprünglichen Vaskularisationsgrenze erreicht werden. In einem einzigen Auge kam es trotz allem zu einer Netzhautverziehung mit konsekutiver frustraner Netzhautchirurgie. Vor IVB war die Leckage in ⅔ auf Proliferationen zurückzuführen (12 Augen/6 Kinder). Bei Rezidiven nach IVB zeigte sich eine Verschiebung des Leckageortes nach posterior (14 Augen/4 Kinder), während nach Laserkoagulation Leckagen durch Proliferationen auch anterior der Vaskularisationsgrenze beobachtet wurden (5 Augen/3 Kinder). Eine Therapieindikation bei fehlenden Pluszeichen und nicht erkennbaren Proliferationen in der Weitwinkelfotografie ergab sich bei 14 Augen/4 Kindern aufgrund von angiografischen Aktivitätszeichen. Schlussfolgerungen Die intravitreale Injektion von 0,312 mg Bevacizumab zeigte sich als effektive Behandlungsmethode des APROP-Akutstadiums. Der langfristige Therapieerfolg erforderte die konsequente Erfassung und Behandlung von APROP-Rezidiven. Besonders hilfreich war dabei die Fluoreszenzangiografie in der Diagnostik von nicht erkennbaren Rezidiven in der Weitwinkelfotografie.
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Zhao, Guohua, Laszlo T. Vaszar, Daoming Qiu, Lingfang Shi, and Peter N. Kao. "Anti-inflammatory effects of triptolide in human bronchial epithelial cells." American Journal of Physiology-Lung Cellular and Molecular Physiology 279, no. 5 (2000): L958—L966. http://dx.doi.org/10.1152/ajplung.2000.279.5.l958.
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Triptolide (PG490, 97% pure) is a diterpenoid triepoxide with potent anti-inflammatory and immunosuppressive effects in transformed human bronchial epithelial cells and T cells (Qiu D, Zhao G, Aoki Y, Shi L, Uyei A, Nazarian S, Ng JC-H, and Kao PN. J Biol Chem 274: 13443–13450, 1999). Triptolide, with an IC50of ∼20–50 ng/ml, inhibits normal and transformed human bronchial epithelial cell expression of interleukin (IL)-6 and IL-8 stimulated by phorbol 12-myristate 13-acetate (PMA), tumor necrosis factor-α, or IL-1β. Nuclear runoff and luciferase reporter gene assays demonstrate that triptolide inhibits IL-8 transcription. Triptolide also inhibits the transcriptional activation, but not the DNA binding, of nuclear factor-κB. A cDNA array and clustering algorithm analysis reveals that triptolide inhibits expression of the PMA-induced genes tumor necrosis factor-α, IL-8, macrophage inflammatory protein-2α, intercellular adhesion molecule-1, integrin β6, vascular endothelial growth factor, granulocyte-macrophage colony-stimulating factor, GATA-3, fra-1, and NF45. Triptolide also inhibits constitutively expressed cell cycle regulators and survival genes cyclins D1, B1, and A1, cdc-25, bcl-x, and c-jun. Thus anti-inflammatory, antiproliferative, and proapoptotic properties of triptolide are associated with inhibition of nuclear factor-κB signaling and inhibition of genes known to regulate cell cycle progression and survival.
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SASTROSUPADI, ADJI, BUDI SANTOSO, and DJUMALI. "PENGARUH ZAT PENGATUR TUMBUH DAN PUPUK PELENGKAP CAIR TERHADAP PERTUMBUHAN DAN PRODUKSI RAMI DI WONOSOBO." Jurnal Penelitian Tanaman Industri 9, no. 1 (2020): 4. http://dx.doi.org/10.21082/jlittri.v9n1.2003.4-10.
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<p>Tanaman rami (Boehmeria nivea) dipanen setiap dua bulan, sehingga hara yang tcrangkut melalui panen cukup besar. Untuk itu dilakukan percobaan pembeian zat pengatur tumbuh (ZPT) dan pupuk pelengkap cair (PPC) yang dimulai pada bulan April 2001. Ixikasi percobaan di Desa Sedayu, Sapuran, Kab. Wonosobo pada jenis tanah latosol coklat dan tipe iklim Bl Tujuan penelitian untuk mengctahui/mempelajai pengaruh /.PT dan PPC serta kombinasinya dalam memacu pertumbuhan vegetatif klon Pujon 10 dan Jawa Timur. Perlakuan disusun secara faktorial dalam rancangan petak terbagi dengan tiga ulangan Perlakuan petak utama terdiri atas macam klon rami. yaitu Pujon 10 dan Jawa Timur, sedangkan anak petak berupa pembeian ZPT, PPC. dan ZPT ' PPC tcrdii atas scmbilan macam yang meliputi : (1) 60 N + 20 P,Oj * 60 KjO ' 10 ton pupuk kandang sapi, (2) 60 N • 20 P20, • 60 KjO - 10 ton pupuk kandang sapi • ZPT 1 (kons 1 ml/1), (3) 60 N • 20 PjO, + 60 K20 &gt; 10 ton pupuk kandang sapi • ZPT 2 (0 5 ml/I); (4) 60 N * 20 P20, ♦ 60 KjO ♦ 10 ton pupuk kandang sapi * PPC 1 (3 g/l); (5) 60 N • 20 P20, - 60 K20 t 10 ton pupuk kandang sapi • PPC 2 (0.65 gl); (6) 60 N &lt; 20 P205 + 60 K20 + 10 ton pupuk kandang sapi ♦ ZPT 1 + PPC I, (7) 60 N + 20 P2Os + 60 K20 r 10 ton pupuk kandang sapi t ZPT1 + PPC 2, (8) 60 N - 20 P2O5 * 60 KjO 1 10 ion pupuk kandang sapi + ZPT 2 + PPC 1 dan, (9) 60 N + 20 P2Oj + 60 K20 t 10 ton pupuk kandang sapi + ZPT 2 l- PPC 2. Ukuran petak 3 6 m x 6 m, jarak tanam 60 cm x 40 cm. Hap lubang ditanam satu stck rhi/.om panjang 8 cm Hasil percobaan menunjukkan bahwa pembeian ZPT 1 * PPC 2 dan ZPT 2 * PPC 2 dengan pemupukan NPK melalui lanah dapat meningkatkan pertumbuhan vegetatif dan hasil serat dibanding dengan pemupukan melalui tanah saja. Peningkatan hasil serat panen II • III masing-masing mencapai 58% (dari 565 2 kg/ha tanpa ZPT - PPC menjadi 895.0 kg/ha) dan 61% (dai 565.2 kg/ha tanpa ZPT + PPC menjadi 908.5 kg/ha). Potensi hasil klon Pujon 10 lebih besar dibandingkan dengan klon Jawa Timur.</p><p>Kata kunci : Boehmeria nivea, ZPT, PPC, pupuk kandang</p><p> </p><p><strong>ABSTRACT </strong></p><p><strong>Effect of growth regulators and liquid fertilizers on the growth and yield of ramie in Wonosobo</strong></p><p>Crop removal of ramie plant it very high because it is harvested every 60 days A ield experiment was carried out at Sedayu, Sapuran, Wonosobo since April 2001. Ihe type of soil and climate was brown latosol and Bl respectively. The objective of the expeiment was to study effect of plant regulators, liquid fertilizers (PPC), and its combinations on accelarating vegetative growth on two clones of ramie. The experiment was arranged in split plot design with three replicatins The main plots were two clones of ramie (Pujon 10 and Jawa Timur) and the sub plots were nine treatments consist of plant regulators, liquid fertilizer, and its combination were tried as sub treatment (I) 60 N &gt; 20 P2Oj » 60 K20 + 10 tons manure of cow waste; (2) 60 N * 20 P2Os * 60 K20 I 10 tons manure of cow + ZPT I (kons I ml/1); (3) 60 N « 20 P2Os • 60 KjO * 10 tons manure of cow + ZPT 2 (0.5 ml/1); (4) 60 N + 20 P2Os * 60 KjO I 10 ions manure of cow + PPC 1 (3 g/l); (5) 60 N + 20 P20, + 60 K20 + 10 ions manure of cow &lt; PPC 2 (0 65 g/l); (6) 60 N &gt; 20 P2Oj I 60 K20 * 10 tons manure of cow • ZPT 1 1 PPC I. (7) 60 N * 20 PjO, ♦ 60 KjO + 10 Ions manure of cow ♦ ZPT I * PPC 2, (8) 60 N ♦ 20 P20, ► 60 K20 + 10 tons manure of cow ♦ ZPT 2 • PPC I, and, (9) 60 N ♦ 20 P2Os i 60 K20 ♦ 10 tons manure of cow ♦ ZPT 2 + PPC 2. The plot size was 3.6 m x 6 m, wih 60 cm x 40 cm of plant spacing, and one rhizome of 8 cm length per hole. Results showed that aplication of ZPT I ♦ PPC 2 and ZPT 2 t PPC 2 with NPK fertilizers increase vegetatif growth and yield of iber. The total harvest II t III increased by 58% and 61% respectively. Potential yield of Pujon 10 was higher than Jawa Timur.</p><p>Key words : Boehmeria nivea, growth regulators, liquid fertilizer, cow manure</p>
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Douglas, Pauline, Lauren Ball, Lynn McGuffin, et al. "Hydration: Knowledge, Attitudes, and Practices of UK Dietitians." Journal of Biomedical Education 2015 (August 6, 2015): 1–6. http://dx.doi.org/10.1155/2015/172020.
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Aim. The aim of this study was to investigate dietitians’ knowledge, attitudes, and practices (KAP) regarding hydration and patient care. Methods. A cross-sectional online survey was administered to UK dietitians via the British Dietetic Association monthly newsletter and included 18 items on hydration knowledge (n=8), attitudes (n=4), and practices (n=6). KAP scores were calculated by adding the total number of correct knowledge responses and by ranking attitude and practice responses on a Likert scale. Results. 97 dietitians completed the online survey and displayed varying levels of KAP regarding hydration and patient care. The mean unweighted scores were knowledge 5.0 (±1.3) out of 8; attitude 13.9 (±1.3) out of 16; practice 14.9 (±2.6) out of 24. Dietitians appeared to be guided by clinical reasoning and priorities for nutrition care. Conclusions. There may be scope to further assess and potentially enhance the KAP of dietitians regarding hydration and patient care. Innovative approaches to hydration promotion are warranted and may include focusing on dietitians’ personal hydration status, increasing communication with other healthcare professionals, and partnering with patients to take a proactive role in hydration monitoring.
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Suryani, Irma, Asep Efendi, and Fitriana Fitriana. "Pengaruh Pengalaman, Independensi, Gender Auditor Terhadap Kualitas Audit." Syntax Idea 3, no. 2 (2021): 307. http://dx.doi.org/10.36418/syntax-idea.v3i2.1041.
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Penelitian ini dilakukan karena banyaknya kasus kegagalan audit yang mghasilka kualitas audit yag buruk, diduga pengalaman,independesi, gender auditor brpgaruh terhadap kualitas audit didukung dengan adanya inkonsistensi hasil penelitian terdahulu. Populasi pada penelitian adalah auditor tetap yang bekerja diKAP Jakarta Pusat yang terdaftar di direktorat IAPI 2019. Jumlah populasi penelitian adalah 265 auditor.Penentuan ukuran sampel menggunakan rumus Slovin. Teknik pengambilan sampel yang digunakan yaitu probability sampling denan jumlah sampel dalam penelitian ini adalah 72 auditor tetap. Metode penelitian yang digunakan adalah metode deskriptif dan verifikatif. Metode analisis data menggunakan analisis regresi linier berganda dengan menggunakan SPSS 20. Hasil penelitian membuktikan bahwa: (1) pengalaman auditor di KAP Jakarta Pusat termasuk kategori tinggi (2) independensi auditor di KAP Jakarta Pusat termasuk kategori sangat tinggi (3) gender auditor di KAP Jakarta Pusat di dominasi oleh laki-laki, hasil penelitian menunjukan auditor wanita lebih baik dalam mengaudit.(4) kualitas auditor di KAP Jakarta Pusat termasuk kategori tinggi,(5)pengalaman auditor berpengaruh negatif dan tidak signifikan terhadap kualitas audit secara parsial,(6) Independensi berpengaruh positif dan signifikan terhadap kualitas audit secara parsial,(7) gender berpengaruh negatif dan signifikan terhadap kualitas audit secara parsial, (8)pengalaman, independensi, gender auditor berpengaruh terhadap kualitas audit secara simultan.
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Karuniawati, Hidayah, Mohamed Azmi Ahmad Hassali, Sri Suryawati, Wan Ismahanisa Ismail, Taufik Taufik, and Md Sanower Hossain. "Assessment of Knowledge, Attitude, and Practice of Antibiotic Use among the Population of Boyolali, Indonesia: A Cross-Sectional Study." International Journal of Environmental Research and Public Health 18, no. 16 (2021): 8258. http://dx.doi.org/10.3390/ijerph18168258.
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Misuse and overuse of antibiotics are potential causes of the increasing prevalence of antibiotic resistance (ABR). Having information about the knowledge, attitude, and practices concerning antibiotics use by the public might help control ABR growth. Therefore, this cross-sectional study aimed to investigate the levels and associated factors of knowledge, attitude, and practice (KAP) of antibiotics use among the public. A questionnaire was designed and validated, which consisted of a total of 51 questions with four sections: demographics (6), knowledge (20), attitude (12), and practice (13) to measure KAP. Univariate analysis (using Mann–Whitney U and Kruskal–Wallis analysis) was applied to assess the differences in the mean scores of KAP. Linear regression analysis was performed to identify factors associated with KAP. Finally, using Spearman analysis we have examined the correlation between responses to the KAP. The sample size of this study was 575, with a 99.96% response rate. Regarding knowledge, 73.12% of respondents stated that antibiotics could be used to treat viral infections, and 63.35% of respondents answered that antibiotics could reduce fever. Concerning attitude, 50% of respondents had considered stopping taking antibiotics as soon as symptoms had disappeared. In analyzing practice, we found 40% of respondents obtained antibiotics from a pharmacy without a prescription from a physician, a nurse, or a midwife. Statistical analysis revealed that KAP about antibiotic use was significantly associated with gender, area of residence, level of education, and monthly income (p < 0.05). Our findings concluded that men, respondents with low income, those with low-level education, and those living in rural areas are more prone to excessive use of antibiotics without knowing the adverse effects of improper use and how it can contribute to high ABR. So it is urgently necessary to strengthen policies on antibiotics use, including drug provision, distribution, and sales. In addition, people with low KAP should be a priority consideration in education outreach initiatives.
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Anyanwu, Madubuike Umunna, Chiamaka Felicitas Okpalanwa, and Raymond Nduka Ugwuanyi. "Occurrence and Antibiogram of Extended-Spectrum Cephalosporin- and Cephamycin-Resistant Escherichia coli in Asymptomatic University Students." International Journal of Enteric Pathogens 7, no. 2 (2019): 31–36. http://dx.doi.org/10.15171/ijep.2019.09.
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Background: Apparently healthy individuals could serve as reservoirs and disseminators of extendedspectrum cephalosporin (ESC)- and cephamycin (cefoxitin, FOX)-resistant, and extended-spectrum β-lactamase-producing (ESBL-P) Escherichia coli which jeopardizes antibacterial therapy thereby posing a threat to the health of infected individuals/carriers. Objectives: This study aimed to screen healthy asymptomatic students in the University of Nigeria, Nsukka (UNN) as potential reservoirs of ESC- and FOX-resistant and ESBL-P E. coli and to determine the antibacterial resistance profile. Materials and Methods: Anal swabs were collected from 190 randomly selected healthy asymptomatic students of both genders in UNN between March and July 2018. ESC-resistant E. coli was isolated using MacConkey agar with 2 µg/mL ceftazidime. ESBL production was assessed by combination disc method while cephamycin resistance was determined using cefoxitin disc screening. Phenotypic resistance of the isolates was determined using disc diffusion method. Results: Out of 190 samples, 20 (10.2%) demonstrated growth. Of these, 6 (30%) were FOX resistant (putative AmpC-producers) but none produced ESBL. The resistance of the isolates was 100% to ampicillin (AMP), 95% to ceftazidime (CAZ), tetracycline (TET) and sulfamethoxazole-trimethoprim (SXT), 30% to FOX and chloramphenicol (CHL), 85% to ciprofloxacin (CIP), enrofloxacin (ENR) and streptomycin (STR), and 65% to kanamycin (KAN). All the isolates were susceptible to meropenem (MEM). Among the 20 isolates, 1 (5%) was resistant to 2 classes of antibacterial agents while 19 (95%), including all the FOX-resistant strains, were resistant to ≥ 3 classes of antibacterial agents. The isolates exhibited 11 multiple antibacterial resistance patterns with AMP, CAZ, FOX, TET, CIP, ENR, STR, KAN, SXT being predominant. Conclusion: Healthy asymptomatic students in UNN are potential reservoirs and disseminators of ESC- and cephamycin (FOX)-resistant E. coli.
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Sari, Caecilia Mesian Anggit, and Rustiana Rustiana. "Pemetaan Penerapan Standar Audit Berbasis ISA Pada Kantor Akuntan Publik (KAP) di Daerah Istimewa Yogyakarta." MODUS 28, no. 1 (2016): 23. http://dx.doi.org/10.24002/modus.v28i1.663.
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Abstrak Tujuan dari penelitian ini adalah untuk memetakan penerapan standar auditing berdasarkan International Standards on Auditing (ISA) di Kantor Akuntan Publik (KAP) di Yogyakarta. Penelitian ini merupakan penelitian kualitatif yang menggunakan wawancara mendalam dan kuesioner terbuka untuk mengumpulkan data dari KAP. Sampel penelitian adalah 6 dari 12 KAP di Yogyakarta. Analisis data menggunakan analisis deskriptif dan wawancara intensif dengan para pengambil keputusan dari KAP (manajer atau partner). Hasil penelitian menunjukkan bahwa 50% dari KAP di Yogyakarta berada pada tahap mengetahui (level 1), 17% pada tahap aplikasi (level 3), dan 33% pada tahap pendidikan (level 4). Implikasi dari penelitian ini adalah bahwa KAP di tingkat 1 harus berkontribusi secara aktif untuk mencari informasi tentang audit dari badan usaha kecil berdasarkan ISA yang telah diterbitkan oleh Ikatan Akuntan Indonesia. Pertanyaan dan Jawaban (TJ) buku pegangan berisi prinsip-prinsip audit yang berbasis ISA untuk badan usaha kecil dan menengah. Buku panduan ini dimaksudkan untuk membantu auditor dalam menerapkan standar audit yang relevan secara efektif dan efisien. Kata kunci: International Standards on Auditing (ISA), Kantor Akuntan Publik, Auditor Abstract The aim of this study is to map the application of the auditing standards based on the International Standards on Auditing (ISA) at public accounting firms in Yogyakarta. This study is a qualitative research that uses in-depth interviews and open-questionnaires to collect data from public accounting firms. The research sample consists of 6 of 12 public accounting firms. Data were analyzed by using descriptive analysis and intensive interviews with the decision makers of public accounting firms (managers or partners). The results show that 50% of public accounting firms in Yogyakarta are at the stage of knowing (level 1), 17% at the application stage (level 3), and 33% at the stage of education (level 4). The implication of this study is that the public accounting firms at level 1 should contribute actively to seek information about the audit of small business entities based on ISA which has been issued by the Indonesian Institute of Accountants. The Questions and Answers (TJ) handbook contains the ISA-based audit principles for small and medium business entities. This handbook is intended to assist the auditor in applying relevant audit standards effectively and efficiently. Keywords: International Standard on Auditing (ISA), Public Accounting Firm, Auditor
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SKINNER, GUY E., TRAVIS R. MORRISSEY, EDUARDO PATAZCA, et al. "Effect of High Pressures in Combination with Temperature on the Inactivation of Spores of Nonproteolytic Clostridium botulinum Types B and F." Journal of Food Protection 81, no. 2 (2018): 261–71. http://dx.doi.org/10.4315/0362-028x.jfp-17-175.
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ABSTRACT The impact of high pressure processing on the inactivation of spores of nonproteolytic Clostridium botulinum is important in extended shelf life chilled low-acid foods. The three most resistant C. botulinum strains (Ham-B, Kap 9-B, and 610-F) were selected for comparison of their thermal and pressure-assisted thermal resistance after screening 17 nonproteolytic C. botulinum strains (8 type B, 7 type E, and 2 type F). Spores of strains Ham-B, Kap 9-B, and 610-F were prepared using a biphasic media method, diluted in N-(2-acetamido)-2-aminoethanesulfonic acid (ACES) buffer (0.05 M, pH 7.00) to 105 to 106 CFU/mL, placed into a modified sterile transfer pipette, heat sealed, and subjected to a combination of high pressures (600 to 750 MPa) and high temperatures (80 to 91°C) using laboratory and pilot-scale pressure test systems. Diluted spores from the same crops were placed in nuclear magnetic resonance tubes, which were heat sealed, and subjected to 80 to 91°C in a Fluke 7321 high precision bath with Duratheram S oil as the heat transfer fluid. After incubation for 3 months, survivors in both studies were determined by the five-tube most-probable-number method using Trypticase–peptone–glucose–yeast extract broth. The highest (&gt;5.0) log reductions in spore counts for Ham-B, Kap 9-B, and 610-F occurred at the highest temperature and pressure combination tested (91°C and 750 MPa). Thermal D-values of Ham-B, Kap 9-B, and 610-F decreased as the process temperature increased from 80 to 87°C, decreasing to &lt;1.0 min at 87°C for these strains. Pressure-assisted thermal D-values of Ham-B, Kap 9-B, and 610-F decreased as the process temperature increased from 80 to 91°C with any pressure combination and decreased to &lt;1.0 min as the pressure increased from 600 to 750 MPa at 91°C. Based on the pressure-assisted thermal D-values, pressure exerted a more protective effect on spores of Ham-B, Kap 9-B, and 610-F when processed at 83 to 91°C combined with pressures of 600 to 700 MPa when compared with thermal treatment only. No protective effect was observed when the spores of Ham-B, Kap9-B, and 610-F were treated at lower temperatures (80 to 83°C) in combination with 750 MPa. However, at higher temperatures (87 to 91°C) in combination with 750 MPa, a protective effect was seen for Ham-B, Kap9-B, and 610-F spores based on the calculated pressure-assisted thermal D-values.
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Story, Sherry V., Claudia Shah, Francis E. Jenney, and Michael W. W. Adams. "Characterization of a Novel Zinc-Containing, Lysine-Specific Aminopeptidase from the Hyperthermophilic Archaeon Pyrococcus furiosus." Journal of Bacteriology 187, no. 6 (2005): 2077–83. http://dx.doi.org/10.1128/jb.187.6.2077-2083.2005.
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ABSTRACT Cell extracts of the proteolytic, hyperthermophilic archaeon Pyrococcus furiosus contain high specific activity (11 U/mg) of lysine aminopeptidase (KAP), as measured by the hydrolysis of l-lysyl-p-nitroanilide (Lys-pNA). The enzyme was purified by multistep chromatography. KAP is a homotetramer (38.2 kDa per subunit) and, as purified, contains 2.0 ± 0.48 zinc atoms per subunit. Surprisingly, its activity was stimulated fourfold by the addition of Co2+ ions (0.2 mM). Optimal KAP activity with Lys-pNA as the substrate occurred at pH 8.0 and a temperature of 100°C. The enzyme had a narrow substrate specificity with di-, tri-, and tetrapeptides, and it hydrolyzed only basic N-terminal residues at high rates. Mass spectroscopy analysis of the purified enzyme was used to identify, in the P. furiosus genome database, a gene (PF1861) that encodes a product corresponding to 346 amino acids. The recombinant protein containing a polyhistidine tag at the N terminus was produced in Escherichia coli and purified using affinity chromatography. Its properties, including molecular mass, metal ion dependence, and pH and temperature optima for catalysis, were indistinguishable from those of the native form, although the thermostability of the recombinant form was dramatically lower than that of the native enzyme (half-life of approximately 6 h at 100°C). Based on its amino acid sequence, KAP is part of the M18 family of peptidases and represents the first prokaryotic member of this family. KAP is also the first lysine-specific aminopeptidase to be purified from an archaeon.
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Rastogi, Aayushi, Sabin Syed, Tarika Sharma, et al. "Enhancing the health coverage in India by empowering the corona warriors through educational intervention." International Journal Of Community Medicine And Public Health 8, no. 7 (2021): 3305. http://dx.doi.org/10.18203/2394-6040.ijcmph20212325.
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Background: The aim of the study was to assess the effect of the training program on knowledge, attitude and practice (KAP) related to prevention and management of COVID-19.Methods: A pre-post study was conducted among healthcare workers (HCWs) attending ten-days online training program from 29 April to 30 November, 2020. A 37-item questionnaire assessing knowledge (26-items), attitude (6-items) and practice (5-itmes) was administered to the participants before and after the training program. Total score of knowledge, attitude and practice (KAP) was 27, 12 and 20 respectively. Paired t test was used to assess the effect of training on KAP. Association of pre-training KAP with demographic variables was performed using SPSSv-22.Results: A total of 1428 HCWs were trained across 25 states through nine trainings; however, the data was analysed for only 1167 HCWs (response rate: 82%). Mean age of participants was 30.96±6.62 years and 77.29% were females. Mean KAP scores in pre-training were found to be 17.46±3.24 out of 27, 9.94±1.56 out of 12 and 19.01±1.76 out of 20 respectively which significantly increased to 21.28±3.65, 10.35±1.48 and 19.37±1.49 after attending training program. Pre-knowledge score was found to be associated with age, years of experience, geographical location, type of facility, presence of COVID-19 related facilities in the place of working.Conclusions: Comprehensively designed training program enhanced the knowledge about prevention and management of COVID-19 in HCWs and also motivated them to maintain an optimistic attitude and good practices while managing the patients.
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George, Ajin K., Jewel V.g, Meenu Manohar, Sarath P. Kumar, and Muneerudeen J. "IMPACT OF PATIENT COUNSELLING ON KNOWLEDGE, ATTITUDE, PRACTICES OF PATIENTS WITH TYPE 2 DM AT A TERTIARY CARE TEACHING HOSPITAL." Asian Journal of Pharmaceutical and Clinical Research 10, no. 5 (2017): 293. http://dx.doi.org/10.22159/ajpcr.2017.v10i5.17637.
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ABSTRACTObjectivesTo evaluate the impact of counselling in terms of KAP outcomes.MethodologyA randomized prospective controlled study was conducted for a period of 6 months in the General Medicine OPD of SSIMS & RC. Patients enrolled were randomized into test and control groups. Suitably designed and validated KAP Questionnaire was applied at baseline and final follow up for both groups. Results At the end of the study, knowledge and attitude levels were markedly improved in test group patients. The FBS of the patients in the test group were found to be significant (p<0.00) when compared from baseline to second assessement whereas in control group no significant changes were observed (*p> 0.05).ConclusionThe study concluded that the improved knowledge and attitude clearly indicates the benefits of pharmacist provided counselling, although they did not translate into improved practice outcomes. The study observed that, hospital pharmacists can play a key role in management of DM and patient care.KEYWORDS: KAP, Patient counselling, Type 2 DM.
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Fodor, László. "főszerkesztő előszava." Pro Futuro 10, no. 1 (2020): 7–8. http://dx.doi.org/10.26521/profuturo/2020/1/8566.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Mulu, Wondemagegn, Chalachew Genet Akal, Kidist Ababu, et al. "Seroconfirmed Typhoid Fever and Knowledge, Attitude, and Practices among Febrile Patients Attending at Injibara General Hospital, Northwest Ethiopia." BioMed Research International 2021 (April 13, 2021): 1–8. http://dx.doi.org/10.1155/2021/8887266.
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Introduction. Typhoid fever (TF) is a febrile global health problem caused by Salmonella enterica serovar Typhi (S. Typhi) with relatively high prevalence in low- and middle-income countries including Ethiopia. Identifying local prevalence and gaps in knowledge, attitude, and practice (KAP) towards TF is recommended by the World Health Organization to implement preventive measures. Therefore, this study determined the prevalence of S. Typhi and KAP of febrile patients towards TF in Injibara General Hospital, Northwest Ethiopia. Methods. Hospital-based cross-sectional study was conducted from January to March 2020. A total of 237 patients were included conveniently. Data on KAP and demographic variables were collected using a structured questionnaire by face-to-face interview. After the interview, 5 ml venous blood was collected and processed using the Widal test following the manufacturer’s instruction. Mean scores and percentages were used to determine the level of KAP. Multivariable analysis was done to correlate KAPs with TF. P value < 0.05 was considered statistically significant. Results. The overall prevalence of S. Typhi was 25.7%. The highest seroprevalence was observed among the age group of 30-34 years (33.3%) and patients with no education. The majority of participants know the major ways of TF transmission (59.1-90.7%) and prevention (81.4%) methods. However, the misconception on the route of TF transmission was observed in 13.5-36.7% of participants. About 65.4% and 67.5% of study participants were considered knowledgeable and had good preventive practice towards TF, respectively. Being a student ( AOR = 0.227 , CI = 0.053 − 0.965 ) and considering mosquito bite as transmission routes ( AOR = 2.618 , CI = 1.097 − 6.248 ) were significantly associated with TF. Conclusion. High S. Typhi prevalence was observed in the study area. Moreover, the misconception on the transmission of typhoid fever and educational level was a risk factor for TF. Thus, health facilities should incorporate topics on typhoid fever as part of their health education system within health facilities and in the community.
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Sam, Gloria K., Jobin Thomas, Riya Alexander, and Sheen Ann Varughese. "ASSESSMENT & EVALUATION ON THE KNOWLEDGE, ATTITUDE & PRACTICE TOWARDS MEDICATION THERAPY MANAGEMENT AMONG COMMUNITY OF DAVANGERE CITY." Asian Journal of Pharmaceutical and Clinical Research 10, no. 4 (2017): 380. http://dx.doi.org/10.22159/ajpcr.2017.v10i4.16889.
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Objectives: The prime objective of this study is to assess knowledge, attitude, and practice (KAP) toward medications in a community of Davangere city.Methods: This community-based study was conducted for 6 months using medication therapy management aspects. Ethical clearance was obtainedfrom the Institutional Ethical Committee. Patients above 18 years of age who were willing to participate were included in the study. The data werecollected using specific data collection forms, and KAP toward medications of each patient was assessed using KAP questionnaire. Medicationadherence was analyzed using Morisky Medication Adherence Scale 4. Patient counseling about disease, medication, and lifestyle modification wasgiven, and the orally taking household drugs were segregated according to class and specific clinical uses.Results: Out of 129 patients, 58.1% were male. Out of 19 diseases encountered during the study, diabetes mellitus (32.56%) and hypertension(25.58%) were most prevalent. Majority of patients (63.57%) were prescribed with cardiovascular agents. Paracetamol was found as a commonhousehold drug. Sixty-nine percent of patients were procuring medication directly from the pharmacy and the remaining 31% were procuring theirmedication after consulting the physician. Mean scores of KAP in basal and endpoint assessment were compared using Student’s t-test. p value wasfound to be <0.000.Conclusion: The study tried to entitle the name of pharmacist as a patient educator who gives proper guidance to the patient and family membersabout the disease, domestic drug management, lifestyle modification, etc. The result of efficient patient counseling will be reflected on the properadherence of patient toward the medication and improved quality of life.Keywords: Knowledge, attitude and practice (KAP), Medication therapy management (MTM), Morisky medication adherence Scale – 4 (MMAS-4),patient education.
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Skrk, Damijan, Katja Petek, Dean Pekarovic, and Nejc Mekis. "Typical air kerma area product values for trauma orthopaedic surgical procedures." Radiology and Oncology 55, no. 2 (2021): 240–46. http://dx.doi.org/10.2478/raon-2020-0066.
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Abstract Background The aim of study was to establish the typical radiation quantity values for the most common trauma orthopaedic surgical procedures and to compare them with reference values of equivalent procedures performed in other institutions. In addition, we assess the impact of image intensifier and flat panel detector technology used for fluoroscopically guidance on patient exposure. Materials and methods Five most frequently performed fluoroscopically guided trauma orthopaedic procedures in University Medical Centre Ljubljana were analysed. Data on 199 cases over a 6 months period from December 2016 to June 2017 were gathered retrospectively. Study covered 40 dynamic hip screw fixations (DHS), 23 proximal femoral nail insertions (PFN), 20 proximal humeral nail insertions (PHN), 77 partial hip endoprosthesis implantations (PEP) and 39 percutaneous posterior spine fixations (PPS). The median and average along with the first and third quartile values of air kerma area product (KAP) for each procedure type were calculated as well as median and average value of fluoroscopy screening time. Results Typical KAP value for dynamic hip screw fixation was set at 0.52 Gycm2; for proximal femoral nail insertion at 0.53 Gycm2 and for proximal humeral nail insertion at 0.26 Gycm2. For implantation of partial endoprosthesis typical KAP value utilizing flat panel technology was set at 0.08 Gycm2 and at 0.21 Gycm2 when the image intensifier technology was used. Typical KAP value for percutaneous posterior spine fixation was set at 1.26 Gycm2, using flat panel technology and at 3.98 Gycm2 using image intensifier technology. Conclusions Established typical KAP levels of surgical orthopaedic procedures in traumatology will serve as a valuable tool for further radiation exposure optimization.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 9, no. 1 (2019): 7–8. http://dx.doi.org/10.26521/profuturo/2019/1/5450.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 2, no. 2 (2012): 6–7. http://dx.doi.org/10.26521/profuturo/2012/2/5548.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 3, no. 1 (2013): 7–9. http://dx.doi.org/10.26521/profuturo/2013/1/5515.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 3, no. 2 (2013): 7–8. http://dx.doi.org/10.26521/profuturo/2013/2/5502.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 4, no. 1 (2014): 7–8. http://dx.doi.org/10.26521/profuturo/2014/1/5490.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 4, no. 2 (2014): 7–9. http://dx.doi.org/10.26521/profuturo/2014/2/5468.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 5, no. 1 (2015): 7–8. http://dx.doi.org/10.26521/profuturo/2015/1/5397.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 5, no. 2 (2015): 7–8. http://dx.doi.org/10.26521/profuturo/2015/2/5354.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 6, no. 1 (2016): 7–8. http://dx.doi.org/10.26521/profuturo/2016/1/4890.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.
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Fodor, László. "A főszerkesztő előszava." Pro Futuro 6, no. 2 (2016): 7–9. http://dx.doi.org/10.26521/profuturo/2016/2/5127.
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A főszerkesztő előszavában ismerteti az adott lapszám tartalmát, a cikkekről szóló 5-6 soros leírások (annotációk) formájában. A folyóiratot érintő, legújabb változások mellett itt kap helyet a hátsó borítón szereplő, latin mondás magyarázata.