Academic literature on the topic '6-dihydro-1'

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Journal articles on the topic "6-dihydro-1"

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Collins, David J., Timothy C. Hughes, and Wynona M. Johnson. "Dihydro-1,2,4-triazin-6(1H)-ones. II Synthesis of Several Methylated 3-Phenyl- 4,5-dihydro-1,2,4-triazin-6(1H)-ones." Australian Journal of Chemistry 52, no. 5 (1999): 379. http://dx.doi.org/10.1071/ch99012.

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Novel syntheses of 4,5-dihydro-1,2,4-triazin-6(1H)-ones were developed by use of imidoyl chlorides. The overall yield of 4,5-dihydro-1,2,4-triazin-6(1H)-ones prepared from amino acid imidates and hydrazines was improved by the development of a much more efficient synthesis of the imidates. The new 1,2-, 1,4- and 5,5-dimethyl dihydro-1,2,4-triazin-6(1H)-ones have been synthesized by cyclocondensation/cycloaddition pathways. Base-catalysed methylation of 3-phenyl-4,5-dihydro-1,2,4-triazin-6(1H)-one (15) gave the 1- methylated derivative (8); under similar conditions 2-methyl-3-phenyl-2,5-dihydro
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Dhaval, Hingrajia, Thanki Pragna, and Modha Jayesh. "Synthesis and Characterization of some Benzylidinehydrazinyl Derivatives of Newer Pyrimidine-5-Carbonitrile Moiety." International Letters of Chemistry, Physics and Astronomy 39 (October 2014): 28–34. http://dx.doi.org/10.18052/www.scipress.com/ilcpa.39.28.

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Condensation of 2-hydrazinyl-1,6-dihydro-1-methyl-6-oxo-4-isobutylpyrimidine-5-carbonitrile (3) with different aromatic aldehyde gave the corresponding 2-(Benzylidinehydrazinyl)-1,6-dihydro-6-oxo-4-isobutylpyrimidine-5-carbonitrile (4). The reaction between 1,6-dihydro-1-methyl-2-(methylthio)-6-oxo-4-isobutylpyrimidine-5-carbonitrile (2) with hydrazine hydrate furnished (3). The condensation of 1,2,3,4-tetrahydro-4-oxo-6-isobutyl-2-thioxopyrimidine-5-carbonitrile (1) with methyl iodide yielded 2. Finally the products were characterized by 1H NMR, Mass and IR Spectra.
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Dhaval, Hingrajia, Thanki Pragna, and Modha Jayesh. "Synthesis and Characterization of some Benzylidinehydrazinyl Derivatives of Newer Pyrimidine-5-Carbonitrile Moiety." International Letters of Chemistry, Physics and Astronomy 39 (October 2, 2014): 28–34. http://dx.doi.org/10.56431/p-sa74y0.

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Condensation of 2-hydrazinyl-1,6-dihydro-1-methyl-6-oxo-4-isobutylpyrimidine-5-carbonitrile (3) with different aromatic aldehyde gave the corresponding 2-(Benzylidinehydrazinyl)-1,6-dihydro-6-oxo-4-isobutylpyrimidine-5-carbonitrile (4). The reaction between 1,6-dihydro-1-methyl-2-(methylthio)-6-oxo-4-isobutylpyrimidine-5-carbonitrile (2) with hydrazine hydrate furnished (3). The condensation of 1,2,3,4-tetrahydro-4-oxo-6-isobutyl-2-thioxopyrimidine-5-carbonitrile (1) with methyl iodide yielded 2. Finally the products were characterized by 1H NMR, Mass and IR Spectra.
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Karaburun, Ahmet Cagri, Nalan Gundogdu-Karaburun, Leyla Yurttas, Ismail Kayagil, and Seref Demirayak. "Synthesis and Anticancer Activity of Some 1H-inden-1-one Substituted (Heteroaryl)Acetamide Derivatives." Letters in Drug Design & Discovery 16, no. 2 (2018): 111–18. http://dx.doi.org/10.2174/1570180815666180606081042.

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Background: The synthesis of 2-[3/4-((6-substituted-1-oxo-2,3-dihydro-1H-inden-2- ylidene)methyl)phenoxy]-N-(heteroaryl)acetamide derivatives and the investigation of their anticancer activity were studied. Methods: 2-(3/4-Hydroxybenzylidene)-6-substituted-2,3-dihydro-1H-inden-1-ones were reacted with suitable 2-chloroacetamides to give 2-[3/4-((6-substituted-1-oxo-2,3-dihydro-1H-inden-2-ylidene) methyl)phenoxy]-N-(heteroaryl)acetamide derivatives. Results: The structure elucidation of the newly synthesised 16 compounds was performed by IR, 1H-NMR, mass spectroscopic data and elemental analyse
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Bremner, JB, та W. Jaturonrusmee. "Manganese(III) Acetate-Induced Formation of a Fused, Chloro-Substituted β-Lactam Derivative From a Chloroacetamide". Australian Journal of Chemistry 43, № 8 (1990): 1461. http://dx.doi.org/10.1071/ch9901461.

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Reaction of 1-chloroacetyl-5-methoxy-2,3-dihydro-1H-dibenzo[de,h]quinoline (1) with manganese(III) acetate in acetic acid at 50° gave the novel fused spiro derivative 11-chloro-4-methoxy-1,2-dihydro-6H-azeto[2,1-f]dibenzo[de,h]quinoline-6,12(11H)-dione (6) in 21% yield, together with 5-methoxy-7H-dibenzo[de,h]quinolin-7-one (3), 5-methoxy-2,3-dihydro-7H-dibenzo[de,h]quinolin-7-one (4), and 1- chloroacetyl-5-methoxy-2,3-dihydro-1H-dibenzo[de,h]-quinolin-7-yl ethanoate (5) in 1, 3 and 44% yields respectively. Compound (5) was shown to be a precursor of (3), (4) and (6).
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Collins, David J., Timothy C. Hughes, and Wynona M. Johnson. "Dihydro-1,2,4-triazin-6(1H)-ones. III. Oxidation Products of 1-Methyl-3-phenyl- 4,5-dihydro-1,2,4-triazin-6(1H)-one." Australian Journal of Chemistry 52, no. 10 (1999): 971. http://dx.doi.org/10.1071/ch99047.

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1-Methyl-3-phenyl-4,5-dihydro-1,2,4-triazin-6(1H)-one (1) undergoes aerial oxidation to give a mixture of 1- methyl-3-phenyl-1,2,4-triazin-6(1H)-one (2) and 1-methyl-3-phenyl-1,4-dihydro-1,2,4-triazine-5,6-dione (3). The dehydro derivative (2) was cleanly prepared by the oxidation of (1) with 2,3-dichloro-5,6-dicyano-1,4- benzoquinone (ddq). The dehydro derivative (2) underwent a surprising rearrangement to the triazole (12) upon oxidation with OxoneR. Several attempts at unambiguous synthesis of the α-dicarbonyl derivative (3) were unsuccessful; it was obtained, together with the 1,4-dimethyl
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Santosh B. Gaikwad, Jagannath S. Godse, Amardeep R. Jadhao, and Kishore Puri. "Determination of Antimicrobial Effects of Dihydropyrano [2, 3-c] Pyrazole Derivatives Catalysed by MnFe₂O₄." International Journal of Scientific Research in Science and Technology 12, no. 4 (2025): 78–84. https://doi.org/10.32628/ijsrst251264.

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A recent study discovered antibacterial and antifungal compounds, highlighting their potential future importance in medicinal chemistry. The some Selected derivatives of dihydropyrano[2, 3-c]pyrazoles motif i.e. 6-amino-1,4-dihydro-3-methyl-4-(4-nitrophenyl)-1-phenylpyrano[2,3-c] pyrazole-5-carbonitrile shows excellent bacterial activity against Klebsiella pneumoniae and 6-amino-1,4-dihydro-4-(2,5-dimethoxyphenyl)-3-methyl -1-phenylpyrano[2,3-c]pyrazole-5-carbonitrile against Salmonella enterica serovar Typhimurium, whereas 6-amino-1,4-dihydro-4-(2-hydroxyphenyl)-3-methyl-1-phenylpyrano[2,3-c]
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Rádl, Stanislav. "Preparation of 1-Hydroxyxanthen-9(9H)-ones and 1-Hydroxyacridin-9(10H)-ones via Corresponding 3,4-Dihydro-1,9(2H)-diones." Collection of Czechoslovak Chemical Communications 60, no. 12 (1995): 2127–36. http://dx.doi.org/10.1135/cccc19952127.

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Target 10-cyclopropyl-7-fluoro-1-hydroxy-6-(4-methyl-1-piperazinyl)acridin-9(10H)-one (IVc) and 7-fluoro-1-hydroxy-6-(4-methyl-1-piperazinyl)-9H-xanthen-9-one (IVd) were obtained from corresponding difluoro derivatives IVa and IVb, respectively. These intermediates were synthesized via respective 3,4-dihydro-1,9(2H)-diones Va and Vb. Acridine derivative (10-cyclopropyl-6,7-difluoro-3,4-dihydro-1H-acridine-1,9(2H,10H)-dione, Va) was synthesized from 1-cyclopropyl-6,7-difluoroisatoic anhydride (XI) and xanthene derivative (6,7-difluoro-3,4-dihydro-1H-xanthen-1,9(2H)-dione, Vb) from cyclohexenone
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Rádl, Stanislav, and Lenka Kovářová. "Some reactions of N-propadienyl-4-quinolones." Collection of Czechoslovak Chemical Communications 56, no. 11 (1991): 2413–19. http://dx.doi.org/10.1135/cccc19912413.

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N-Alkylation of ethyl 6,7,8-trifluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate (Vg) with 3-bromopropyne followed by acidic hydrolysis provided N-propyl derivative Ic which in alkaline media yielded N-propadienyl derivative IId. Propadienyl derivatives IIa and IIb treated with primary or secondary amines provided intermediates IIIa-IIIc which were hydrolyzed to N-acetonyl derivatives IVa and IVb, respectively. N-Benzylation of ethyl 7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylate (Va) followed by hydrolysis yielded 1-benzyl-7-chloro-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic ac
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Małecka, Magdalena, Lilianna Chęcińska, Joachim Kusz, Marta Biernacka, and Bogumiła Kupcewicz. "Interactions in flavanone and chalcone derivatives: Hirshfeld surface analysis, energy frameworks and global reactivity descriptors." Acta Crystallographica Section C Structural Chemistry 76, no. 3 (2020): 212–24. http://dx.doi.org/10.1107/s2053229620001503.

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The present study examines a series of flavanone and chalcone derivatives substituted with electron-withdrawing groups (Cl or Br) and electron-donating groups (OH, CH3 and OCH3), namely, 7-methoxy-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one, C16H14O3, 2-(4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one, C16H14O3, 2-(4-methoxyphenyl)-6-methyl-3,4-dihydro-2H-1-benzopyran-4-one, C17H16O3, 2-(4-chlorophenyl)-3,4-dihydro-2H-1-benzopyran-4-one, C15H11ClO2, 8-bromo-6-methyl-2-phenyl-3,4-dihydro-2H-1-benzopyran-4-one, C16H13BrO2, (2E)-1-(2-hydroxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one, C16H14O3,
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Dissertations / Theses on the topic "6-dihydro-1"

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Stretch, W. "The chemistry of 3-ethoxycarbonyl-5, 6-dihydro-4H-1, 2-oxazines : An approach to the synthesis of betagamma-deydroaminoacids." Thesis, University of Liverpool, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370847.

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Edmont, Blotière Dolores. "Synthèse et réactivité de la 6-fluoro-4-oxo-1, 4-dihydro-2-quinoléinecarboxylate de méthyle : Elaboration de novuelles molécules tricycliques à structure 1,2,4-triazino. Evaluation biologique dans le domaine hypoglycémiant." Orléans, 1999. http://www.theses.fr/1999ORLE2009.

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Le diabete mellitus, maladie metabolique, est un syndrome de plus en plus frequent, qui se rencontre a tous les ages de la vie. Des donnees recentes revelent l'existence d'environ 130 millions de diabetiques dans le monde et leur nombre pourrait bien doubler d'ici 2025. Dans le cadre d'une recherche de nouveaux agents hypoglycemiants permettant de traiter les causes et les consequences du diabete non insulino-dependant, nous avons prepare, a partir d'un synthon de base de 6-fluoro-4-oxo-1,4-dihydro-2-quinoleinecarboxylate de methyle, des composes du type 4-oxo-1,4-dihydroquinoleinique diversem
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Raghupathi, N. "Studies toward the total syntheses of skipped polyol natural products: strictifolione, 6R-6-[(4R,6R)-4,6-dihydroxy-10-phenyldec-1-enyl]-5,6-dihydro-2H-pyran-2-one, marinomycin A, (+)-cryptocarya diacetate." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2008. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/2690.

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Binay, Patrice. "Nouveaux modèles du NADH : réactivité et énantiosélectivité." Rouen, 1986. http://www.theses.fr/1986ROUES001.

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Dans une première partie, synthèse d'alkyl-4 dihydro-1,4 benzyl-1 et -phényl-1p éthyl-1 (diméthyl-4,4 oxazoline-2yl-2)-3 pyridines et étude de leur activité réductrice vis-a-vis de p-nitrobenzaldéhyde et de benzenéglyoxylate de méthyle en présence de mg**(2+) ; dans la seconde partie, étude de modèles plus énantiosélectifs : méthyl-1 dihydro-1,4 n-(hydroxyméthyl-1 propyl) nicotinamide (=méthyl-1 a), o-, m- et p- xylylene-1, 1' bis-a, dihydro-1,4 methyl-1 nicotinate de (dihydro-1,4 methyl-1 nicotinoylamino)-2 butyle et le cyclophane correspondant à ce dernier composé (pont xylylene entre les az
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Pochet, Sylvie. "Synthèse d'oligodésoxynucléotides comportant des sites ambigus ou apuriniques et de sondes ancrées à un support solide." Paris 6, 1986. http://www.theses.fr/1986PA066065.

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Synthèse et étude par spectroscopies RMN, IR et DC d'oligodésoxyribonucléotides contenant un résidu sans base: coexistence des conformations b et z sur un même duplex. Elaboration d'une base universelle dans la série des nucléosides pyrimidiques. Synthèse d'oligodésoxynucléotides ancrés à un support solide; applications.
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VALLEE, PAULE YOLANDE. "Obtention par thermolyse eclair et etude physicochimique de molecules conjuguees reactives d'interet synthetique ou astrophysique." Caen, 1988. http://www.theses.fr/1988CAEN2033.

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Dupas, Georges. "Synthèse et réactivité de modèles du NADH : modèles chiraux, modèles greffés." Rouen, 1987. http://www.theses.fr/1987ROUES007.

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Ferroud, Clotilde. "Étude de la réaction de Diels-Adler intra et intermoléculaire sous haute pression : application à la synthèse stéréosélective d'alcaloïdes de l'indole du groupe des yohimbanes." Paris 6, 1986. http://www.theses.fr/1986PA066023.

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Le schéma de synthèse repose sur une unité bicyclique, précurseur direct des unités (d,e) du squelette pentacyclique. Cet intermédiaire est basé sur une réaction de Diels-Alder sous haute pression, utilisant la cycloaddition de diènes de structure donneur-accepteur 1,4 avec une lactone insaturée comme diénophile. La synthèse du système pentacyclique est exposée à partir de cet intermédiaire clé.
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Lin, Wen-Zhu, and 林文珠. "The synthesis and diels-alder reaction of 1, 4-dihydro-6-p-toluenesulfonylpyrrolo [3,4-d] 2,3-oxathiin-3-oxide." Thesis, 1994. http://ndltd.ncl.edu.tw/handle/66093707443654579592.

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Book chapters on the topic "6-dihydro-1"

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of radical anion obtained by the reduction of bis(1, 2, 6, 7-tetracyano-3, 5-dihydro-3, 5-diiminopyrrolizinido)palladium(II)." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53971-2_831.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-methylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_81.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-acylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_83.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-butylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_84.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-2-phenylethylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_85.

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Pardasani, R. T., and P. Pardasani. "Molar magnetic moment of iron(III) mixed ligand complex with nicotinic acid [1-(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4yl)-methylidine]hydrazide and 1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 2. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62466-1_82.

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Gangjee, A., Y. Zeng, J. J. McGuire, R. L. Kisliuk, and E. Chu. "Synthesis of N-[4-[(2-Amino-6-Methyl-3,4-Dihydro-4-Oxo-7H-Pyrrolo[2,3-d]-Pyrimidin-5-Yl)Methyl]Benzoyl]-L-Glutamic Acid as an Antifolate." In Chemistry and Biology of Pteridines and Folates. Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0945-5_74.

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Keglevich, Gy, and H. Szelke. "2,3-Dihydro-1-phosphole 1-Oxides by Base-Catalyzed Rearrangement of 6-Oxa-3-phosphabicyclo[3.1.0]hexanes." In Ene-X Compounds (X=S, Se, Te, N, P). Georg Thieme Verlag KG, 2007. http://dx.doi.org/10.1055/sos-sd-033-00856.

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Sujana, K., A. V. Surendra, K. V. Kishore, SK Reehana, and C. B. Himakalyani. "Phytochemical Analysis and Characterization of Ethanolic Extract of Pseuderanthemum Malabaricum Whole Plant." In Current Trends in Drug Discovery, Development and Delivery (CTD4-2022). Royal Society of Chemistry, 2023. http://dx.doi.org/10.1039/9781837671090-00735.

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Ancient times onwards mankind is dependent on the plants and other natural resources for the new chemical molecules in search of beneficial phytochemicals for therapy. Present study was intended to find out such phytochemicals in the ethanolic extract of Pseuderanthemum malabaricum which may become useful molecules in pharmacological perspective. Shade dried whole plant of Pseuderanthemum malabaricum was powdered and extracted with ethanol using Soxhlet extractor. Preliminary phytochemical analysis of ethanolic extract showed the presence of steroids, terpenoids, saponins, coumarins, flavonoid
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Taber, Douglass F. "The Li Synthesis of Daphenylline." In Organic Synthesis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780190646165.003.0088.

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The genus Daphniphyllum consists of 25–30 species of evergreen trees and shrubs of south Asia. The leaves and roots are widely used in Chinese herbal medicine. About 250 alkaloids, many with complex polycyclic structures, have been isolated from these species. Of these, daphenylline 3 is unique in incorporating a benzene ring. Ang Li of the Shanghai Institute of Organic Chemistry envisioned (Nature Chem. 2013, 5, 679) a route to 3 based on the diastereoselective intramolecular Michael cyclization of 1 to 2. Following the work of Piers (J. Org. Chem. 1996, 61, 8439), the preparation of 1 began
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Conference papers on the topic "6-dihydro-1"

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Tarkka, Richard M., David J. Brady, and Gary B. Schuster. "Volume holographic storage in spiropyrans." In OSA Annual Meeting. Optica Publishing Group, 1993. http://dx.doi.org/10.1364/oam.1993.thf.5.

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Interconversion between metastable states of photochromic molecules can modulate the absorption and refractive index of doped polymer media. We describe the diffraction efficiency, sensitivity, and response times of holograms written with 633-nm light and erased with incoherent ultra-violet light using the commercially available benzospiropyran 1′,3′-dihydro-1′,3′,3′-trimethyl-6-nitrospiro[2H-1-benzopyran-2,2′-(2H)-indole] in various polymer hosts.
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Amala, S., G. Rajarajan, E. Dhineshkumar, M. Arockia Doss, and M. Seenivasan. "Design synthesis and characterization of 2-(4,5-dihydro-2,4,5-triphenylimidazol-1-Yl)-6-methylpyridine:FT-IR, NMR, and computational investigation." In RECENT TRENDS IN PURE AND APPLIED MATHEMATICS. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5135176.

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El Rayes, S. M. "Convenient synthesis of some methyl-N-[2-(6-oxo-3-p-tolyl-5,6-dihydro-4H-pyridazin-1-yl)-acetamide]alkanoates." In The 12th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2008. http://dx.doi.org/10.3390/ecsoc-12-01204.

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El Rayes, S. "Convenient synthesis of some methyl-N-[2-(6-oxo-3-p-tolyl-5,6-dihydro-4H-pyridazin-1-yl)-acetamide]alkanoates." In The 12th International Electronic Conference on Synthetic Organic Chemistry. MDPI, 2008. http://dx.doi.org/10.3390/ecsoc-12-01228.

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Wang, Suh-Miin, Lee Muei Chng, Montha Meepripruk, and Pek-Lan Toh. "Vibrational frequencies and electronic structures of 2-amino-1, 9-dihydro-9-[(2-hydroxuethoxy) methyl]-6H-purin-6-one using density functional theory method." In INTERNATIONAL SYMPOSIUM ON GREEN AND SUSTAINABLE TECHNOLOGY (ISGST2019). AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5126545.

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Milanović, Žiko, Marko Antonijević, Dušica Simijonović, Jelena Đorović Jovanović, and Marijana Stanojević Pirković. "Investigating the potential inhibitory effect of the megaphone (molecule) on nasopharyngeal cancer growth factor receptors." In 2nd International Conference on Chemo and Bioinformatics. Institute for Information Technologies, University of Kragujevac, 2023. http://dx.doi.org/10.46793/iccbi23.682m.

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Nasopharyngeal cancer (NPC) is a type of cancer that originates in the nasopharynx, which is the upper part of the throat behind the nasal cavity. Like other cancers, the growth and progression of nasopharyngeal cancer are influenced by various proteins involved in cell signaling, growth regulation, and tumor development such as Epidermal Growth Factor Receptor (EGFR), Vascular Endothelial Growth Factor (VEGF), Fibroblast growth factor receptor (FGFR) and Cyclin D1 (CD1). Megaphone ((1′R,5′R,7R,8S)-7-Hydroxy-3,4,5,5′-methoxy-5′,6′-dihydro-2′H-8,1′-neolign-8′-en-2′-one, MG) is the main componen
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Cheung, Yiu-Yin, Jason R. Buck, Michael L. Nickels, Dewei Tang, and H. Charles Manning. "Abstract 110: Preclinical evaluation of 7-chloro-N,N,5-trimethyl-4-oxo-3(6-[18F]fluoropyridin-2-yl)-3,5-dihydro-4H-pyridazino[4,5-b]indole-1-acetamide: A novel pyridazinoindole ligand for PET imaging of TSPO in cancer." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-110.

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