Log in

Relevant bibliographies by topics / 6-diphenylpyrimidine

Contents

Journal articles

Academic literature on the topic '6-diphenylpyrimidine'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic '6-diphenylpyrimidine.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "6-diphenylpyrimidine"

1

MAKULA, Dr AJITHA, and SANA TABASSUM. "SYNTHESIS OF NOVEL 4,6-DIPHENYLPYRIMIDINE SUBSTITUTED BENZAMIDE DERIVATIVES ITS CHARACTERIZATION AND EVALUATION FOR ANTI-OXIDANT AND ANTI-MICROBIAL ACTIVITIES." Journal of Advanced Scientific Research 14, no. 04 (2023): 13–25. http://dx.doi.org/10.55218/jasr.202314404.

Full text

Abstract:

The research work involves the estimation and evaluation of pharmacological activity of designed 4, 6-diphenylpyrimidine substituted benzamide derivatives that act as HDAC inhibitors. The Histone deacetylases inhibitors are a new class of cytostatic agents that exhibits promising results cancer treatment. The four HDAC inhibitors approved by FDA for cancer chemotherapy is SAHA (Vorinostat), Belinostat (PXD-101), Panobinostat (LBH-589), and Romidepsin (FK-228). The six novel 4, 6-diphenylpyrimidine substituted benzamide derivatives were synthesized, characterized and evaluated for anti-microbia

APA, Harvard, Vancouver, ISO, and other styles

2

Dr., M. Ajitha Raj* N. Sandhya Rani2. "In-Silico studies of Novel 4, 6-diphenylpyrimidine substituted Benzamide derivatives on HDAC enzymes." Journal of Pharma Research 11, no. 03 (2022): 15–25. https://doi.org/10.5281/zenodo.6844684.

Full text

Abstract:

<strong><em>ABSTRACT</em></strong> <strong>The present study attempts to investigate the 4,6-diphenylpyrimidine substituted benzamide derivatives that act as HDAC inhibitors. Histone deacetylases (HDACs) have been widely recognized as promising targets for cancer treatment. It has been three decades ago, that the first potent Zn2+ dependent histone deacetylase inhibitor was recognized. Meanwhile, to date, SAHA (Vorinostat), Belinostat (PXD-101), Panobinostat (LBH-589), and Romidepsin (FK-228) four HDAC inhibitors have been approved by FDA for cancer chemotherapy, while more than 10 HDAC inhibi

APA, Harvard, Vancouver, ISO, and other styles

3

Bumber, A. A., O. D. Lalakulich, N. V. Shibaeva, M. E. Kletskii, and A. I. Pyshchev. "Electrochemical interconversion of 1-(p-tolyl)-6-methyl-2,4-diphenylpyrimidinium perchlorate and 1-(p-tolyl)-6-methylene-2,4-diphenylpyrimidine." Chemistry of Heterocyclic Compounds 35, no. 1 (1999): 68–71. http://dx.doi.org/10.1007/bf02251664.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Korona-Głowniak, Izabela, Wojciech Nitek, Waldemar Tejchman, and Ewa Żesławska. "Influence of chlorine and methyl substituents and their position on the antimicrobial activities and crystal structures of 4-methyl-1,6-diphenylpyrimidine-2(1H)-selenone derivatives." Acta Crystallographica Section C Structural Chemistry 77, no. 10 (2021): 649–58. http://dx.doi.org/10.1107/s205322962100975x.

Full text

Abstract:

Derivatives of 4-methyl-1,6-diphenylpyrimidine-2(1H)-selenone show very strong antimicrobial activity. In order to extend the current knowledge about the features responsible for the biological activity, crystal structure analyses are presented for 4-methyl-1-(2-methylphenyl)-6-phenylpyrimidine-2(1H)-selenone (1), 4-methyl-1-(3-methylphenyl)-6-phenylpyrimidine-2(1H)-selenone (2), 4-methyl-1-(4-methylphenyl)-6-phenylpyrimidine-2(1H)-selenone (3) (all C18H16N2Se) and 1-(4-chlorophenyl)-4-methyl-6-phenylpyrimidine-2(1H)-selenone (4) (C17H13ClN2Se). Furthermore, the antibacterial and antifungal ac

APA, Harvard, Vancouver, ISO, and other styles

5

Bumber, A. A., O. D. Lalakulich, N. V. Shibaeva, M. E. Kletskii, and A. I. Pyshchev. "ChemInform Abstract: Electrochemical Interconversion of 1-(p-Tolyl)-6-methyl-2,4-diphenylpyrimidinium Perchlorate and 1-(p-Tolyl)-6-methylene-2,4-diphenylpyrimidine." ChemInform 31, no. 1 (2010): no. http://dx.doi.org/10.1002/chin.200001180.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Kuvaeva, E. V., Yu M. Ladutko, D. A. Kolesnik, P. O. Levshukova, and E. V. Fedorova. "Synthesis and determination of the activity of a new derivative of hydroxyoxopyrimidine, a potential object for the manufacture of anti-inflammatory gel." JOURNAL of SIBERIAN MEDICAL SCIENCES 6, no. 1 (2022): 46–55. http://dx.doi.org/10.31549/2542-1174-2022-6-1-46-55.

Full text

Abstract:

Introduction. Compounds with a hydroxypyrimidine fragment in their structure exhibit pronounced and diverse biological activity. The low solubility of many hydroxypyrimidine derivatives in water is a significant drawback in the development of new medicines. From 5-butyl-6-hydroxy-2,3-diphenylpyrimidin-4(3H)-one, its water-soluble form being a sodium salt was obtained. This compound, as it was revealed during the computer screening of its possible biological acti¬vity in silico, can potentially be used as a pharmaceutical substance for the production (manufacture) of drugs. Since the line of hy

APA, Harvard, Vancouver, ISO, and other styles

7

Anantoju, Kishore Kumar, Laxminarayana Eppakayala, and Thirumala Chary Maringanti. "Eco-friendly Synthesis of 3-(Aryl)-2,6-diphenylpyrimidin-4(3H)-ones, Ethyl-1-(aryl)-1,6-dihydro-2-(aryl)-6-oxopyrimidine-4-carboxylates and 6-(4-Arylphenyl)-2-isopropylpyrimidin-4(3H)-one." Asian Journal of Chemistry 31, no. 4 (2019): 845–50. http://dx.doi.org/10.14233/ajchem.2019.21784.

Full text

Abstract:

In present communication, we report the synthesis of pyrimidin-4(3H)-one derivatives by microwave irradiation in good yields and less reaction time. All titled compounds were characterized by IR, NMR and Mass spectral analyses.

APA, Harvard, Vancouver, ISO, and other styles

8

Ravikumar, Yuvaraj, Pimpisid Koonyosying, Sirichai Srichairatanakool, Lakshmi Naryanan Ponpandian, Jayanthi Kumaravelu та Somdet Srichairatanakool. "In Silico Molecular Docking and Dynamics Simulation Analysis of Potential Histone Lysine Methyl Transferase Inhibitors for Managing β-Thalassemia". Molecules 28, № 21 (2023): 7266. http://dx.doi.org/10.3390/molecules28217266.

Full text

Abstract:

A decreased hemoglobin synthesis is contemplated as a pathological indication of β-thalassemia. Recent studies show that EPZ035544 from Epizyme could induce fetal hemoglobin (HbF) levels due to its proven capability to inhibit euchromatin histone lysine methyl transferase (EHMT2). Therefore, the development of EHMT2 inhibitors is considered promising in managing β-thalassemia. Our strategy to find novel compounds that are EHMT2 inhibitors relies on the virtual screening of ligands that have a structural similarity to N2-[4-methoxy-3-(2,3,4,7-tetrahydro-1H-azepin-5-yl) phenyl]-N4,6-dimethyl-pyr

APA, Harvard, Vancouver, ISO, and other styles

9

Żesławska, Ewa, Izabela Korona-Głowniak, Wojciech Nitek, and Waldemar Tejchman. "Effect of the position of a methoxy substituent on the antimicrobial activity and crystal structures of 4-methyl-1,6-diphenylpyrimidine-2(1H)-selenone derivatives." Acta Crystallographica Section C Structural Chemistry 76, no. 4 (2020): 359–66. http://dx.doi.org/10.1107/s2053229620004040.

Full text

Abstract:

Derivatives of pyrimidine-2(1H)-selenone are a group of compounds with very strong antimicrobial activity. In order to study the effect of the position of the methoxy substituent on biological activity, molecular geometry and intermolecular interactions in the crystal, three derivatives were prepared and evaluated with respect to their antimicrobial activities, and their crystal structures were determined by X-ray diffraction. The investigated compounds, namely, 1-(X-methoxyphenyl)-4-methyl-6-phenylpyrimidine-2(1H)-selenones (X = 2, 3 and 4 for 1, 2 and 3, respectively), C18H16N2OSe, showed ve

APA, Harvard, Vancouver, ISO, and other styles

10

Kumar, Naveen, Vijay Kumar, Vinay Kumar, Kailash, and Vinod Kumar. "Design, Synthesis and Evaluation of substituted Chromones as Acetylcholinesterase Inhibitors for the Treatment of Alzheimer’s Disease." Alzheimer's & Dementia 19, S21 (2023). http://dx.doi.org/10.1002/alz.076869.

Full text

Abstract:

AbstractBackgroundAcetylcholinesterase (AChE) is one of the frontline targets involved in the progression of Alzheimer’s disease. AChE inhibitors are prescribed as the few drug therapies that have been proven clinically useful in the treatment of Alzheimer’s disease[1, 2]. AChE is involved in the termination of impulse transmission by rapid hydrolysis of the neurotransmitter acetylcholine in numerous cholinergic pathways[3]. The enzyme inactivation induced by various inhibitors, leads to acetylcholine accumulation, hyperstimulation of nicotine and muscarinic receptor and disrupted neurotransmi

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!