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1

Tkachenko, Viktoriia. "Analysis of the State of Primary Medical Care in the Kyiv Region for 2022: the Impact of War and Occupation." Family medicine. European practices, no. 4 (December 29, 2023): 21–26. http://dx.doi.org/10.30841/2786-720x.4.2023.297021.

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The full-scale invasion of the russian federation into Ukraine led to the fact that, from the first days a significant number of territorial communities of the Kyiv region were in zones of active war activity and were temporarily occupied and suffered direct losses from ongoing hostilities. The objective: to study the state of primary medical care (PMC) in the Kyiv region in 2022. Materials and methods. Statistical reports of PMC institutions of the Kyiv region and reports of the National Health Service of Ukraine were analyzed. Statistical analysis was carried out using Excel 2007, SPSS, Stat
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Lasytsia, T. S., G. Z. Moroz, and I. M. Hidzynska. "MEDICAL AND SOCIOLOGICAL RATIONALE FOR OPTIMIZATION OF CONTINUING PROFESSIONAL DEVELOPMENT OF MEDICAL DOCTORS IN THE FIELD OF TREATMENT OF PATIENTS WITH CORONARY HEART DISEASE AND COMORBIDITIES." Клінічна та профілактична медицина 1, no. 1 (2020): 10–17. http://dx.doi.org/10.31612/2616-4868.1(11).2020.01.

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State Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative Department, Kyiv, Ukraine
 Purpose: to evaluate the awareness about the coronary heart disease (CHD), associated with comorbidities, amongst the internists of the State Institution of Science «Research and Practical Center of Preventive and Clinical Medicine» State Administrative Department (SIS «RPC PCM» SAD), with the consequent working out of the study module «Comorbidities in patients with CHD: up-to-date treatment requirements».
 Material and methods. This integr
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3

Hovalyg, N. M., O. V. Remneva, and O. V. Kolyado. "Epidemiology of premature birth and details of medical evacuation in the Tyva Republic and Altai Territory." Siberian Medical Review, no. 1 (2021): 68–72. http://dx.doi.org/10.20333/2500136-2021-1-68-72.

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The aim of the research is to assess the epidemiology of premature birth and measures for organizing medical evacuation of patients from agricultural regions in vast territory of the Tyva Republic and Altay Territory for the period 2015-2019. Material and methods. Th e statistical reports data on the work of obstetric service in the Tyva Republic and Altay Territory for the period 2015-2019 are analyzed. Th e frequency, structure, dynamics of premature birth, features of organizing medical evacuation have been studied. Th e analysis of the information received was carried out using absolute, r
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Tkachenko, Viktoriia. "Analysis of the State of Primary Medical Care in the Kyiv Region for 2022: the Impact of War and Occupation." Family Medicine. European Practices, no. 4 (December 29, 2023): 21–26. https://doi.org/10.30841/2786-720X.4.2023.297021.

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The full-scale invasion of the russian federation into Ukraine led to the fact that, from the first days a significant number of territorial communities of the Kyiv region were in zones of active war activity and were temporarily occupied and suffered direct losses from ongoing hostilities. <strong>The objective:</strong>&nbsp;to study the state of primary medical care (PMC) in the Kyiv region in 2022. <strong>Materials and methods.</strong>&nbsp;Statistical reports of PMC institutions of the Kyiv region and reports of the National Health Service of Ukraine were analyzed. Statistical analysis
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El_Mashade, Mohamed Bakry, Yahia Zakria Abd Elgawad, and Tarek Mahmoud Nasr. "Fuzzy Logic Controller of New Strategy of Biomedical Measurements." International Journal of Online and Biomedical Engineering (iJOE) 16, no. 10 (2020): 133. http://dx.doi.org/10.3991/ijoe.v16i10.13899.

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&lt;p class="Abstract"&gt;Monitoring patient’s condition represents one of the crucial tasks in any biomedical center to ensure the stability of the patient state. Healthcare sector quality demands are exponentially rising. These demands are concerned with designing expert systems for medical diagnosis. Also, the use of fuzzy sets theory in the medical field is to solve some medical problems. &lt;/p&gt;&lt;p class="Abstract"&gt;This paper proposes a simple strategy of bio measurements and its behavior through fuzzy logic model. The proposed design is constructed using three different types of
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Khan, Maria, Brekhna Jamil, Fatima Muhammad, Nazish Bilal, and Bilqis Hassan. "CLINICAL TEACHERS AS ROLE MODELS: PERCEPTION OF UNDERGRADUATE MEDICAL STUDENTS IN MEDICAL COLLEGES OF PAKISTAN USING ROLE MODEL APPERCEPTION TOOL." Journal of Medical Sciences 31, no. 01 (2023): 10–16. http://dx.doi.org/10.52764/jms.23.31.1.2.

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Objective: This study aimed to determine medical students’ perceptions of their clinical teachers as role models during the clinical years of a medical program. Materials and Methods: In this cross-sectional study, a pre-validated questionnaire, Role Modeling Apperception Tool was used and completed by Final year medical students selected from affiliated medical institutions of Khyber Medical University, Peshawar i.e. four graduating cohorts, comprising about 600 students. Participants were selected following universal sampling and data was analyzed for descriptive and inferential statistics.
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Van Tap, Nguyen, Ho Tat Bang, Duong Thi Huong, Pham Cong Chi, and Le Thi Ngoc Anh. "Malnutrition in hospitalized cancer patients: A single-center, cross-sectional study in Southern Vietnam." SAGE Open Medicine 11 (January 2023): 205031212311714. http://dx.doi.org/10.1177/20503121231171491.

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Objectives: Malnutrition in cancer patients reduces response to chemotherapy, increases the hospitalization costs, hospital infections, and deaths. The aim of this study was to determine the prevalence, level of malnutrition, and its related factors in cancer patients at a local hospital in Southern Vietnam. Methods: A descriptive cross-sectional study was performed on all 118 cancer patients who were undergoing inpatient treatment at Long An General Hospital, Vietnam from May to September 2020. Data were collected from patients by face-to-face interviewing using a subjective global assessment
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8

Roy, Asim, Anne Marie Morse, Jordan Dubow, David Seiden, and Richard Bogan. "491 Efficacy of FT218, a Once-Nightly Sodium Oxybate Formulation, by Narcolepsy Subtype: A Post Hoc Analysis From the REST-ON Study." Sleep 44, Supplement_2 (2021): A194. http://dx.doi.org/10.1093/sleep/zsab072.490.

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Abstract Introduction FT218 is an investigational, once-nightly, controlled-release formulation of sodium oxybate for the treatment of narcolepsy. The purpose of this post hoc analysis of the REST-ON study was to evaluate the effect of FT218 on measures of excessive daytime sleepiness (EDS) in patients with narcolepsy subtypes 1 (NT1) and 2 (NT2). Methods This was a randomized, double-blind, placebo-controlled, multicenter study in patients with narcolepsy ≥16 years old. Patients were stratified by narcolepsy subtypes and randomized 1:1 to receive FT218 or matching placebo: 4.5 g/night for 1 w
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9

Kostiuchenko-Faifor, O. S., I. V. Gunas, N. V. Belik, О. М. Shapoval, and S. P. Veretelnyk. "Cephalometric characteristics of the upper respiratory tract in Ukrainian young men and young women with an orthognathic bite without and with the type of face taken into account." Reports of Morphology 28, no. 3 (2022): 56–61. http://dx.doi.org/10.31393/morphology-journal-2022-28(3)-09.

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The upper respiratory tract is a component of the respiratory system, which ensures the performance of several key human functions at once. The variability of cephalometric indicators of this structure of the human body, depending on the peculiarities of body structure, nationality, sex, and other factors, is one of the current topics of discussion among modern scientists. The purpose of the study is to establish the peculiarities of the cephalometric characteristics of the upper respiratory tract in young people without pathology of the upper respiratory tract with an orthognathic bite withou
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Guo, Lining, Michael V. Milburn, John A. Ryals, et al. "Plasma metabolomic profiles enhance precision medicine for volunteers of normal health." Proceedings of the National Academy of Sciences 112, no. 35 (2015): E4901—E4910. http://dx.doi.org/10.1073/pnas.1508425112.

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Precision medicine, taking account of human individuality in genes, environment, and lifestyle for early disease diagnosis and individualized therapy, has shown great promise to transform medical care. Nontargeted metabolomics, with the ability to detect broad classes of biochemicals, can provide a comprehensive functional phenotype integrating clinical phenotypes with genetic and nongenetic factors. To test the application of metabolomics in individual diagnosis, we conducted a metabolomics analysis on plasma samples collected from 80 volunteers of normal health with complete medical records
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11

Mikulić, Vinka, Ivanka Mikulić, Helena Radić Mišković, et al. "Urine neutrophil gelatinase-associated lipocalin concentration in healthy newborns during the first three postnatal days." Biochemia medica 30, no. 3 (2020): 466–70. http://dx.doi.org/10.11613/bm.2020.030706.

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Introduction: Urine neutrophil gelatinase-associated lipocalin (uNGAL) is a biochemical marker significant for early prediction of acute kidney injury in adults. However, it has not been examined sufficiently among the infant population, particularly newborns in terms of reference values. The aim of our study was to determine the concentration of uNGAL in healthy term newborns and to determine if there was a difference in uNGAL concentration according to gender, postnatal age and birth weight. Materials and methods: Our study involved 81 healthy term newborns birth (≥ 37 weeks, Apgar score ≥ 8
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12

Shirokorad, V. I., D. G. Lupashko, and L. V. Doronin. "The place of multiple primary cancers in urologic oncology." Cancer Urology 19, no. 2 (2023): 127–32. http://dx.doi.org/10.17650/1726-9776-2023-19-2-127-132.

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Background. In Russia, statistical record of multiple primary cancers has been implemented only recently, and there are few scientific publications. Multiple primary malignant neoplasms of the urologic locations are described even less in literature. The problem of multiple tumors becomes more pressing with each passing year.Aim. To perform retrospective study of statistical data on urologic multiple primary cancer from one department.Materials and methods. An analysis of retrospective data from medical histories of patients who received treatment between 1997 and 2020 in urologic oncology dep
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Raimundo, Karina, Joshua J. Solomon, Amy L. Olson, et al. "Rheumatoid Arthritis–Interstitial Lung Disease in the United States: Prevalence, Incidence, and Healthcare Costs and Mortality." Journal of Rheumatology 46, no. 4 (2018): 360–69. http://dx.doi.org/10.3899/jrheum.171315.

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Objective.Interstitial lung disease (ILD) is commonly associated with rheumatoid arthritis (RA) and can have significant morbidity and mortality. The objective of this study was to calculate the prevalence, incidence, healthcare costs, and mortality of RA-related ILD (RA-ILD) in the United States.Methods.This retrospective cohort analysis used the Truven Health MarketScan Commercial and Medicare Supplemental health insurance databases from 2003 to 2014 and the Social Security Administration death database. Patients with RA-ILD were selected based on diagnoses on medical claims. Outcomes were 1
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14

Napolitano, Mariasanta, Luca Valore, Giorgia Saccullo, et al. "Management of Venous Thromboembolism (VTE) in Patients with Acute Leukemia: Results from a Multicenter Study." Blood 124, no. 21 (2014): 3688. http://dx.doi.org/10.1182/blood.v124.21.3688.3688.

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Abstract Background In the last decades, evaluation of thrombotic complications secondary to acute leukemia (AL) has been poorly investigated. Only scant data are available on management and prevention of thrombosis in this setting. We performed a multicenter retrospective study with the aim to evaluate the management of venous thromboembolism (VTE) in patients with AL and to report the most commonly adopted regimens of treatment. Materials and methods Available clinical records of out and in-patients diagnosed with AL from January 2008 to June 2013 in 7 Reference Regional Hospitals were analy
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15

Sachdev, Vandana, Yuan Gu, James Nichols, et al. "A Machine Learning Algorithm to Improve Risk Assessment for Patients with Sickle Cell Disease." Blood 134, Supplement_1 (2019): 893. http://dx.doi.org/10.1182/blood-2019-125846.

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Sickle cell disease (SCD) is a clinical syndrome that encompasses several different genotypes, the 3 most common being homozygosity for the bS allele (HbSS), compound heterozygosity of HbS and HbC (HbSC), and compound heterozygosity of HbS and HbSb thalassemia (HbSb+ or HbSb0 thalassemia). Generally, patients with HbSS and HbSb0 thalassemia genotypes have the most severe clinical manifestations, while patients with HbSC and HbSβ+-thalassemia are thought to be less severe. Within each of these genotypic groups, however, there are also substantial phenotypic differences. This heterogeneity makes
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16

Patel, Khushi S., Cynthia F. Corbett, Elizabeth M. Combs, et al. "Perceptions of COVID-19 and the Use of Health Information Technology Among People Who Are Uninsured: Multimethod Survey Study." JMIR Formative Research 7 (July 28, 2023): e45349. http://dx.doi.org/10.2196/45349.

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Background As of May 2023, the novel SARS-CoV-2 has claimed nearly 7 million lives globally and &gt;1.1 million lives in the United States. Low-income populations are often disproportionately affected by risk factors such as lifestyle, employment, and limited health literacy. These populations may lack the knowledge of appropriate infection precautions or have reduced access to care during illness, particularly in countries without universal health care. Objective We aimed to explore the perceptions and experiences of COVID-19, including symptoms and risk factors among uninsured individuals se
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Johnson, Lawrence R., Gerald C. Miller, and Spencer R. Stout. "Serum Free Light Chains Identify Patients With Monoclonal Gammopathy At Increased Risk Of Developing Renal Disease." Blood 122, no. 21 (2013): 1876. http://dx.doi.org/10.1182/blood.v122.21.1876.1876.

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Abstract Background Monoclonal gammopathy (MG) is frequently associated with kidney disease (monoclonal gammopathy of renal significance; MGRS). International guidelines recommend the use of the serum free light chain (FLC) assay when screening for monoclonal gammopathies; an abnormal FLC ratio and an elevation of at least one FLC isotype indicates an Ig LC clone. However it is not known if, in patients with normal kidney function, the presence of a FLC clone predisposes to the future development of kidney disease. Patients and Methods A 22485 patient database with multiple laboratory tests an
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Newlin Lew, Kelley, Yolanda McLean, Sylvia Byers, Helen Taylor, and Karina Cayasso. "Type 2 diabetes prevention and self-management among Nicaraguan ethnic minorities: findings from phase 3 of a community-based participatory research study." International Journal of Human Rights in Healthcare 10, no. 1 (2017): 28–42. http://dx.doi.org/10.1108/ijhrh-06-2016-0007.

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Purpose The purpose of this paper is to explore physical environmental, medical environmental, and individual factors in a sample of ethnic minority adults with or at-risk for type 2 diabetes (T2D) on the Atlantic Coast of Nicaragua. Design/methodology/approach The study used a cross-sectional descriptive design guided by a community-based participatory research framework. Three coastal communities in the South Atlantic Autonomous Region (RAAS) of Nicaragua were sampled. Inclusion criteria were: lay adult with or at-risk for T2D, ⩾21 years of age, self-identification as Creole or Miskito, and
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19

Nieto, R., R. Quintana, E. Zavala, et al. "AB0618 DELAY TO DIAGNOSIS OF SYSTEMIC LUPUS ERYTHEMATOSUS AND ITS IMPACT ON CUMULATIVE DAMAGE AND MORTALITY: DATA FROM A MULTIETHNIC LATIN AMERICAN COHORT." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1510–11. http://dx.doi.org/10.1136/annrheumdis-2023-eular.4395.

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BackgroundSystemic lupus erythematosus (SLE) SLE often mimics the symptoms of other diseases, and the interval between symptom onset and diagnosis remains long in these patients.ObjectivesTo examine the variables associated with a delay to diagnosis and their impact in damage accrual and mortality in patients with SLE.MethodsGLADEL a multi-ethnic, multi-national Latin-American SLE inception cohort was studied. Patients were recruited based on the physicians’ diagnosis but 97% fulfilled the ACR criteria. Delay to diagnosis was defined as ≥6 months from the first ACR criterion to SLE diagnosis.
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Kostiuchenko-Faifor, O. S., I. V. Gunas, I. M. Kyrychenko, V. V. Vakhovskyi, and S. M. Kosianenko. "Teleroentgenometric parameters of the soft palate in young men and young women with an orthognathic bite without and taking into account the type of face." Reports of Morphology 28, no. 4 (2022): 41–47. http://dx.doi.org/10.31393/morphology-journal-2022-28(4)-06.

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The study of the features of the upper respiratory tract and the relationship of their parameters with other anatomical formations and structures of the human body is one of the promising areas of modern science. Since numerous anatomical components are involved in the functioning of the respiratory tract, their detailed study should be carried out separately. One of these components that is of direct interest to science and practice is the soft palate. The purpose of the study is to establish the peculiarities of the teleroentgenometric parameters of the soft palate in Ukrainian young men and
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Simonoska, Rusana. "Gingival cancer: 11 year follow-up at Karolinska University Hospital (2000-2010)." Journal of Clinical Oncology 30, no. 15_suppl (2012): 5536. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.5536.

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5536 Background: In Sweden, approximately 500-600 cases of oral cancer are diagnosed every year. These include cancer of the gingiva, retromolar trigonum, bucca, hard palate, tongue and floor of the mouth. Each year, around 15 cases of gingival cancer (GC) are diagnosed in the Stockholm region. The goal of this study was to study the onset of symptoms, treatment, prognosis, and sequelae of GC in order to optimize the treatment. Methods: The study consists of a retrospective review of medical records of all diagnosed cases of GC in Stockholm region between 2000-2010, identified through the ENT-
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Mugarab-Samedi, Nargiz, Veronica Mugarab-Samedi, Kayla Parker, and Luis Murguia Favela. "12 Cost-Benefit Analysis of Newborn Screening for Severe Combined Immune Deficiency: literature review and results transferability." Paediatrics & Child Health 25, Supplement_2 (2020): e4-e5. http://dx.doi.org/10.1093/pch/pxaa068.011.

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Abstract Background The purpose of screening for Severe Combined Immune Deficiency (SCID) is to enable timely diagnosis and treatment for this condition. Untreated SCID is uniformly fatal by 2 years of age. Hematopoietic stem cell transplantation is an effective treatment for SCID, and the success rate depends on the age at which it is performed. Earlier treatment improves survival, long term quality of life and decreases costs of treating patients, specifically by shortening hospitalization days. Screening, however, carries short-term implementation costs, that could potentially be a barrier
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23

Melikyan, Anait L., Alla M. Kovrigina, Manana A. Sokolova, et al. "The Role Of Splenectomy In The Treatment Of Myelofibrosis." Blood 122, no. 21 (2013): 4083. http://dx.doi.org/10.1182/blood.v122.21.4083.4083.

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Abstract Background Splenectomy (SE) at the Myelofibrosis (MF) is one of the difficult operations on the techniques and perioperative complications. There are a lot of complications such as inflammatory and adhesive processes, a massive bleeding associated with disorders of hemostasis in thrombocytopenia or thrombocytosis, enlargement of varicose veins, concomitant pathology. A SE doesn’t cure myelofibrosis but may be performed in some cases. Success is unpredictable, and the operative mortality of SE is on the order of 10%. Objectives Evaluate the clinical and hematologic SE efficiency in pat
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KHOMENKO, Olena, and Iryna KOFAN. "Tolerance to ridiculous impacts in school children with a great range of psychological well-being." Journal of Education, Health and Sport 48, no. 1 (2023): 147–57. https://doi.org/10.12775/JEHS.2023.48.01.010.

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<strong>KHOMENKO, Olena and KOFAN, Iryna. Tolerance to ridiculous impacts in school children with a great range of psychological well-being.&nbsp;Journal of Education, Health and Sport. 2023;48(1):147-157. eISSN 2391-8306.&nbsp;</strong><strong>https://dx.doi.org/10.12775/JEHS.2023.48.01.010</strong><strong>https://apcz.umk.pl/JEHS/article/view/47036</strong><strong>https://zenodo.org/records/10223830</strong><strong>&nbsp;</strong><strong>&nbsp;</strong><strong>&nbsp;</strong><strong>The journal has had 40 points in Ministry of Education and Science of Poland parametric evaluation. Annex to t
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Herishanu, Yair, Neta Goldschmidt, Osnat Bairey, et al. "Efficacy and Safety of Frontline Therapy with "FCR" Regimen for Chronic Lymphocytic Leukemia Outside Clinical Trials: Israeli CLL Study Group Experience." Blood 124, no. 21 (2014): 5659. http://dx.doi.org/10.1182/blood.v124.21.5659.5659.

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Abstract The combination of fludarabine, cyclophosphamide and rituximab (FCR) is still currently regarded as the standard regimen for treatment of physically fit patients with chronic lymphocytic leukemia (CLL). This therapy can be associated with significant toxicity, and patient adherence to the protocol may often be difficult outside of clinical trials. This retrospective study aimed to evaluate the efficacy and safety of FCR therapy in the “real life” setting, with particular focus on the influence of dose reduction on treatment outcome. A total of 132 CLL patients (≤70 years of age) treat
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Cozzi, G., M. Lorenzin, M. S. Chimenti, et al. "POS0297 EFFECTIVENESS AND SAFETY OF SECUKINUMAB IN AXIAL SPONDYLOARTHRITIS: A 24-MONTH PROSPECTIVE, MULTICENTER REAL-LIFE STUDY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 395. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4111.

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BackgroundAxial Spondyloarthritis (axSpA) can be distinguished in radiographic axSpA (r-axSpA) and non-radiographic (nr-axSpA). Secukinumab (SEC) is a novel treatment for axSpA, but data from real-life are still missing.ObjectivesTo evaluate, in a multicentric-Italian-cohort of axSpA patients on SEC followed for 24-months: a)the long-term effectiveness and safety of SEC; b)the drug-retention-rate and low-disease-activity (LDA) measured as BASDAI&lt;4/ASDAS&lt;2.1 and very-low-disease-activity (VLDA) measured as BASDAI&lt;2/ASDAS&lt;1.3; c)any differences in outcomes according to: line of biolo
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Yang, Keri, Sizhu Liu, Debra Irwin, et al. "Productivity Loss and Indirect Costs Among Non-Hodgkin Lymphoma Patients and Their Caregivers." Blood 138, Supplement 1 (2021): 4009. http://dx.doi.org/10.1182/blood-2021-148443.

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Abstract Introduction: The impact of cancer care and management beyond treatment is significantly high for cancer patients. Due to the complexities of cancer treatment, patients are heavily reliant upon ancillary support often rendered by friends and family. One significant yet unquantifiable impact of cancer on society is productivity loss of both patients and their caregivers. Non-Hodgkin lymphoma is considered largely incurable with a protracted clinical course punctuated with multiple remission and relapses, warranting repeated treatment and intensive clinical testing, which necessitates s
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Yoshikawa, T., T. Furukawa, T. Hashimoto, M. Morimoto, N. Azuma, and K. Matsui. "AB0401 THE BASELINE SERUM SOLUBLE TNF RECEPTOR LEVELS ARE ASSOCIATED WITH THE RESPONSE OF RHEUMATOID ARTHRITIS PATIENTS TO JAKinibs." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1329.2–1330. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2046.

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BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disease that primarily affects the multiple joints.The elucidation of the pathogenesis of RA has progressed dramatically in recent decades, and among the many cytokines involved in the pathogenesis of RA, interleukin (IL)-6 and TNF-α are known to be the major pro-inflammatory cytokines that are abundant in the bloodstream and synovial tissue. JAK inhibitors (JAKinibs) such as tofacitinib and baricitinib are used in the treatment of RA by inhibiting JAK, which in turn inhibits the signaling of various cytokines including IL-6. However,
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Ishola, Titilope, and Charles T. Quinn. "Transcranial Doppler Peak Systolic Velocities Overestimate The Risk Of Stroke In Sickle Cell Anemia." Blood 122, no. 21 (2013): 2240. http://dx.doi.org/10.1182/blood.v122.21.2240.2240.

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Abstract Background Children with sickle cell anemia (SCA) have a high risk of stroke that can be estimated by transcranial Doppler ultrasonography (TCD). The gold standard TCD measurement to determine the risk of primary stroke is the time-averaged mean of the maximum velocity (TAMMV) in specific intracranial arteries. Peak systolic velocity (PSV), a different TCD measurement, has been proposed as an alternative method for risk stratification, especially for imaging TCD (TCDi) techniques (Jones et al. 2005). Although PSV has been little studied for this purpose, some centers use PSV in additi
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Khomenko, Olena, Oleh Nekhanevych, Sofiia Simonova, Yevgeniia Kovalenko, Valentin Kosse, and Elvira Topka. "Stress resistance and adaptive capacities of cardiovascular system of graduating teenagers with different level of studying load." Journal of Education, Health and Sport 11, no. 8 (2021): 171–81. https://doi.org/10.12775/JEHS.2021.11.08.017.

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<strong>Khomenko Olena, Nekhanevych Oleh, Simonova Sofiia, Kovalenko Yevgeniia, Kosse Valentin, Topka Elvira. Stress resistance and adaptive capacities of cardiovascular system of graduating teenagers with different level of studying load.</strong> <strong>Jou</strong><strong>rnal of Education, Health and Sport. 2021;11(8):171-181. eISSN 2391-8306. DOI http://dx.doi.org/10.12775/JEHS.2021.11.08.017</strong> <strong>https://apcz.umk.pl/czasopisma/index.php/JEHS/article/view/JEHS.2021.11.08.017</strong> <strong>https://zenodo.org/record/5208226</strong> &nbsp; &nbsp; &nbsp; &nbsp; <strong>The jo
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Shimada, Yuka, Daisuke Miura, Ami Inokuchi, et al. "Prognostic Value of t(11;14)(q13;32) in Newly Diagnosed Myeloma Patients in Novel Agent Era; Matched-Pair Analysis." Blood 144, Supplement 1 (2024): 1931. https://doi.org/10.1182/blood-2024-194325.

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Introduction. Multiple myeloma (MM) with t(11;14)(q13;32) is one of the unique subtypes of MM, which is characterized by the consequent upregulation of cyclin D1, lymphoplasmacytic morphology, elevated levels of the antiapoptotic protein BCL-2, and low CD38 expression. In addition, venetoclax has been shown to be effective in MM with t(11;14). In the current era of novel agent, t(11;14) is considered as a standard risk while its prognostic impact is incompletely understood. To clarify the characteristics and the progression of MM with t(11;14), we analyzed our cohort of MM patients over the la
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Manal, Hassan Abd El Aziz, Mohamed Hassan Salama Nagla, Mohamed Magdy Badr El Dine Fatma, Eid Ibrahim Mohamed, and Abd El Aziz Mohamed Abd El Aziz Saffa. "Assessing the role of human ear in sex identification among adult Egyptians: Anthropometric and Radiologic study." Biolife 5, no. 4 (2022): 444–55. https://doi.org/10.5281/zenodo.7379643.

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<strong>ABSTRACT</strong> <strong>Introduction:</strong> Human ear has gained popularity in the field of identification and despite its medico-legal role; it is still underestimated as a probable tool for sex determination. Few, if any, studies have been conducted on Egyptian population to assess its role in identification. <strong>Aim of the work:</strong> To assess sex from the human ear (auricle and semicircular canals), to derive special equations for sex assignment in Egyptians. <strong>Subjects and Methods:</strong> The study sample composed of 260 adult Egyptians divided into two groups
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Fatiah, Mona S. "DETERMINAN AKSES MEMPEROLEH KONDOM PADA KALANGAN LELAKI SEKS LELAKI DI INDONESIA." JURNAL KESEHATAN REPRODUKSI 14, no. 1 (2023): 1–9. http://dx.doi.org/10.58185/jkr.v14i1.54.

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DETERMINAN AKSES MEMPEROLEH KONDOM PADA KALANGAN LELAKI SEKS LELAKI DI INDONESIA DETERMINANTS OF CONDOM ACCESS AMONG MEN HAVE SEX WITH MEN (MSM) IN INDONESIA Mona S Fatiah 1 1Kesehatan Reproduksi, Ilmu Kesehatan Masyarakat, FKM, Universitas Cenderawasih. Jl. Raya Abepura- Sentani, Kota Jayapura, Papua *E-mail: mona.s.fatiah@gmail.com Naskah masuk: dd mm 20xx Review: dd mm 20xx Disetujui terbit: dd mm 20xx Abstract Background: condoms is a form of intervention in preventing HIV transmission in key population groups, especially LSL considering that LSL is thehighest group living with HIV in Indo
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Ami, R. Lokhandwala, and R. Bora Madhumati. "CHANGES ACQUIRED IN PEROXIDASE –A KEY MARKER IN PLANT DEFENSE; UPON ROOT TO ROOT TRANSFER OF GLOMUS GEOSPORUM TO LYCOPERSICON ESCULENTUM MILL." Biolife 2, no. 4 (2022): 1050–59. https://doi.org/10.5281/zenodo.7233142.

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<strong>ABSTRACT</strong> Plant defense responses are strongly stimulated by AM fungi in host plants by control over defense gene expression during establishment of a successful functional symbiosis. Peroxidase requiring compounds are laid down on cell wall as barrier against microbial incursion thus can be used as an indicator in plant defense responses. In the present study, activity and expression of peroxidase was monitored in <em>Glomus geosporum</em> (transferred from roots of <em>Cyperus rotundus</em>) colonized and uncolonized two-weeks-old <em>Lycopersicon esculentum</em> Mill seedlin
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Афолабі Олусегун Еммануель. "A Developmental Perspective to Attention-Deficit Hyperactivity Disorder (ADHD) in Children." East European Journal of Psycholinguistics 3, no. 1 (2016): 8–22. http://dx.doi.org/10.29038/eejpl.2016.3.1.olu.

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The debate about diagnoses and treatment of attention deficit hyperactive disorder (ADHD) in children continue to range on between the developmental and biological perspectives. While there is increasing evidence that support the biological susceptibility of the disorder, a number of researches also emphasized the significant effect of environment on the syndrome. This study used developmental perspectives to evaluate and bring together various bio-psychosocial factors that impact on children diagnosed with ADHD. The study explored and integrated the existing and advancing study on ADHD to a m
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A.V., Redyukov, and Denisova N.A. "RESULTS OF THE SELF-ASSESSMENT OF THE ACTIVITIES OF THE MAIN FREELANCE SPECIALISTS OF THE REGIONAL MINISTRY OF HEALTH." "Medical & pharmaceutical journal "Pulse", March 8, 2025, 72–77. https://doi.org/10.26787/nydha-2686-6838-2025-27-3-72-77.

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The regulatory document “On the main freelance specialists of the Ministry of Health of the Russian Federation” approves 22 functions, 95.5% of which are related to the organization of medical care to the population. The current nomenclature of chief freelance specialists of the Ministry of Health of the Russian Federation includes 96 specialists in the medical profile or nosology. Materials and methods. The study was conducted in a medical organization where the bulk of the regional chief freelance specialists are concentrated. The sample size was 50 people. The survey was carried out in two
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Wójcik, Grzegorz, Izabela Kaczmarek, Krzysztof Zdziarski, and Konrad Jakubowski. "The specificity of work at the Emergency Medical Services and the psychological support of medical rescuers." Pomeranian Journal of Life Sciences 65, no. 3 (2019). http://dx.doi.org/10.21164/pomjlifesci.600.

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Introduction: Professional work is an extremely important aspect of the life of an adult. Probably we all want to be satisfied with this, and not just financially. It can be a source of positive experiences, but also a huge negative burden. It often generates and provides us with many adverse reactions, strains or stresses. The aim of the study was to determine the current status of psychological support to Medical Rescue Teams, and the opinions of medical rescuers on the need for psychological help in their work.Materials and methods: A questionnaire was addressed to medical rescuers across t
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Lucitt, Margaret B., Tom S. Price, Angel Pizarro, et al. "Abstract 613: A Mass Spectrometric Analysis Of Embryonic Zebrafish Proteins." Circulation 116, suppl_16 (2007). http://dx.doi.org/10.1161/circ.116.suppl_16.ii_111-d.

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Zebrafish is an attractive vertebrate model organism for studies into the molecular mechanisms of cardiovascular development, pathology and pharmacology. Studies into the genetics of protein expression are largely constrained by the availability of specific antibodies. Mass spectrometry based proteomics methods have the potential to overcome these hurdles. This requires firstly an accurate characterization of proteins accessible to targeted quantitative analysis. We applied mass spectrometric proteomic methodology and statistical analysis to create profiles of proteins expressed during zebrafi
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Singh, Balbir, Jatinder Singh, Jaskaran Singh, et al. "Morbidity and Mortality Profile among Low Birth Weight Neonates- A Cross-sectional Study from Jalandhar, India." INDIAN JOURNAL OF NEONATAL MEDICINE AND RESEARCH, 2021. http://dx.doi.org/10.7860/ijnmr/2021/50301.2314.

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Introduction: World Health Organisation (WHO) has defined Low Birth Weight (LBW) as weight at birth of fewer than 2,500 grams in the first hour of delivery. This practical cut-off for international comparison is based on epidemiological observations that infants weighing less than 2,500 gm are approximately 20 times more likely to die than babies with a normal birth weight. LBW is closely associated with neonatal and infant mortality and morbidity and stifled growth and cognitive development of children. Aim: To know the aetiological profile and outcome of admitted Low birth weight babies in N
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Han, Ahram, Ae Jeong Jo, Hyunwook Kwon, et al. "Optimum tacrolimus trough levels for enhanced graft survival and safety in kidney transplantation: a retrospective multicenter real-world evidence study." International Journal of Surgery, June 17, 2024. http://dx.doi.org/10.1097/js9.0000000000001800.

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Background: The current study aimed to determine the optimal tacrolimus trough levels for balancing graft survival and patient safety following kidney transplantation. Materials and Methods: We conducted a retrospective cohort study involving 11,868 kidney transplant recipients from five medical centers. The association between tacrolimus exposures (periodic mean trough level, coefficient of variability, time in therapeutic range) and composite allograft outcome (de novo donor specific antibody, biopsy-proven rejection, kidney dysfunction, and graft failure), as well as safety outcomes (severe
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Hynes, Jessica, Jane M. Manfredi, and Sarah A. Shull. "Cranial cruciate ligament disease is perceived to be prevalent and is misunderstood in field trial sport." Journal of the American Veterinary Medical Association, July 14, 2023, 1–6. http://dx.doi.org/10.2460/javma.23.01.0004.

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Abstract OBJECTIVE Cranial cruciate ligament disease (CCLD) is the most prevalent orthopedic problem in canines, affecting 3% to 5% of dogs, causing stifle instability, mobility dysfunction, and pain. The objective of this study was to evaluate the American Kennel Club field trial community’s knowledge of CCLD and estimate its perceived prevalence within this population. SAMPLE 401 field trial participants responded, with 701 field trial canines reported. METHODS A survey instrument was emailed to a population of Retriever field trial participants to collect information on perceptions and expe
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Covington, Elizabeth W., and Addison M. Watkins. "Agreement Between Two-Concentration and One-Concentration Area Under the Curve (AUC) Estimates When Using Bayesian Modeling to Dose Vancomycin in Patients With Obesity." Annals of Pharmacotherapy, August 5, 2023. http://dx.doi.org/10.1177/10600280231190910.

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Background: Vancomycin Bayesian modeling provides 24-hour area under the curve (AUC24) estimations. However, the agreement between two-concentration and one-concentration Bayesian estimates in patients with obesity is unknown. Objective: The purpose of this study was to determine the agreement between two-concentration and one-concentration Bayesian AUC24 estimates in patients with obesity receiving vancomycin. Methods: This retrospective within-subjects cohort study included patients with obesity and two vancomycin concentrations. The first concentration was hidden from dosing software to rec
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Nino de Rivera, Stephanie, Shalom Omollo, Annie Myers, Yihong Zhao, and Ruth M. Masterson Creber. "Abstract 15671: Research Participants Are Hesitant About the NIH’s New Data Sharing Policy and Its Implications for Cardiac Research." Circulation 148, Suppl_1 (2023). http://dx.doi.org/10.1161/circ.148.suppl_1.15671.

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Objective: To evaluate participant preferences for the NIH’s Data Sharing (DMS) Policy and its implications for cardiac research. Introduction: The recent NIH DMS Policy went into effect in January 2023, yet it is unclear how the intended expansion to study data by the public will impact participant willingness to participate in research. Minoritized communities are already underrepresented in research and this could create distrust and increase hesitancy to participate in research. Giving participants options about future use of data, how it is stored and shared all requires further research.
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Amarasekara, Jagath, Lahiru Kodituwakku, Anoja Dheerasinghe, et al. "Timeliness of Treatment Seeking and Public Health Response for Suspected Dengue Cases in Sentinel Sites of Western Province, Sri Lanka." International Journal of Health Systems Resilience, May 23, 2025. https://doi.org/10.51595/injhsr22/020.

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Dengue remains a significant public health challenge in Sri Lanka, with over 50,000 cases reported annually. This study was conducted in the Western Province to evaluate the treatment-seeking behaviour of suspected dengue patients and the timeliness, coverage, and public health response to their notifications. A cross-sectional descriptive study was conducted using a checklist and an interviewer-administered questionnaire through telephone interviews. All eligible patients recorded in the NaDSys web-based system for one month from 15th February were the sampling frame. A total of 361 patients
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van den Bergh, Shea L., Lakeshia T. Logan, Jonathan R. Powell, et al. "Paramedic educational programs maintain entry level competency throughout the COVID‐19 pandemic." Journal of the American College of Emergency Physicians Open 5, no. 5 (2024). http://dx.doi.org/10.1002/emp2.13316.

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AbstractObjectiveThe COVID‐19 pandemic required unprecedented changes to emergency medical services (EMS) educational frameworks in the United States. It is unclear if pandemic‐related changes impacted paramedic educational outcomes. We aimed to evaluate curricular and performance changes resulting from the initial COVID‐19 pandemic on paramedic educational programs.MethodsWe performed a retrospective cross‐sectional evaluation of paramedic educational programs in 2019 and 2020 using the Committee on Accreditation of Educational Programs for the Emergency Medical Services Professions annual re
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Alikova, Z. R., A. A. Tsalikova, T. T. Alikova, and M. V. Tsalikova. "The main directions of improving diabetological care in a polyclinic (based on the results of a sociological study)." Manager Zdravookhranenia, December 2, 2024, 110–16. https://doi.org/10.21045/1811-0185-2024-11-110-116.

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A sociological assessment of satisfaction with outpatient care for patients with diabetes mellitus in the Republic of North Ossetia-Alania was carried out. The results of the study make it possible to identify the main problems faced by patients at the primary health care level and identify possible ways to level them. The purpose of the study: to assess the satisfaction of patients with diabetes mellitus with the quality of medical care provided in outpatient settings. Materials and methods. The questionnaires of 450 patients with diabetes mellitus, urban (66%) and rural (34%) residents were
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Sunarno, Sunarno, Nelly Puspandari, Dwi Febriyana, et al. "Application of Polymerase Chain Reaction in Diphtheria Laboratory Examination: A Field Need." Jundishapur Journal of Microbiology 14, no. 7 (2021). http://dx.doi.org/10.5812/jjm.117884.

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Background: Indonesia is one of the five countries with the highest number of diphtheria cases worldwide. Diphtheria is caused by the toxigenic strains Corynebacterium diphtheriae, C. ulcerans, and C. pseudotuberculosis. The diphtheria-causing bacteria can be identified using conventional and molecular methods, including polymerase chain reaction (PCR) assay. We used the PCR assay as additional testing, because in island countries like Indonesia, specimen transport is a serious challenge to maintaining bacterial survival. Objectives: This study aimed to evaluate the PCR assay as additional tes
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Olusesan, Oyerinde Oyewole, Olaoye Titilayo Abike, Olaposi Basiru Abiola, Oyerinde Oluwayemisi Irene, George Glory Chinyere, and Adeoye Ayodele. "Effect of Socio-demographic Factors and Physical Exercise Training on Cardiovascular Health: Case Study of Fresh Students of Babcock University Ilishan-Remo, Ogun State, Nigeria." Open Sports Sciences Journal 15, no. 1 (2022). http://dx.doi.org/10.2174/1875399x-v15-e2209060.

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Introduction: Sedentary behavior and lack of physical exercise are one of the strongest risk factors for many chronic diseases and conditions, including cardiovascular disease, hypertension, diabetes, obesity, osteoporosis, colon cancer, and depression. Hence, the aim of this study was to assess the combined and relative effect of socio-demographic characteristics and physical exercise (PE) training on the cardiovascular health of freshmen of Babcock University, Ilishan-Remo, Ogun State, Nigeria. Methods: The study was a quasi-experimental study that employed both qualitative and quantitative
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Aladin, Amer I., David Whellan, Robert Mentz, et al. "Abstract P160: Relationship of Physical Function and Quality of Life in Elderly Patients With Acute Decompensated Heart Failure: The Rehabilitation Therapy in Older Acute Heart Failure Patients (The REHAB-HF Trial)." Circulation 137, suppl_1 (2018). http://dx.doi.org/10.1161/circ.137.suppl_1.p160.

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Introduction: Older patients with acute decompensated heart failure (ADHF) have impaired physical function (PF) and reduced quality of life (QOL). However, the relationship between impairments in PF and QOL are unknown but relevant to clinical practice and design of targeted intervention trials in this high-risk population. Methods: We assessed 202 consecutive patients hospitalized with ADHF in the multicenter Rehabilitation Therapy in Older Acute HF Patients (REHAB-HF) Trial. Standard measures of PF included the Short Physical Performance Battery (SPPB), a validated PF outcome measure in frai
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Dr. Edoardo, Pozzi, Fallara Dr. Giuseppe, Belladelli Dr. Federico, et al. "(127) CLINICAL CHARACTERISTICS AT PRESENTATION OF PEYRONIE’S DISEASE PATIENTS HAVE CHANGED OVER THE LAST 20 YEARS." Journal of Sexual Medicine 20, Supplement_4 (2023). http://dx.doi.org/10.1093/jsxmed/qdad062.018.

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Abstract Objectives To detail and explore the changes of clinical and sociodemographic characteristics of a cohort of PD patients over a 17-yr period at a single referral centre. Methods Data from 616 consecutive patients complaining of PD as their primary complaint between 2005 and 2022 were analysed. Health significant comorbidities were scored with the CCI. All patients completed the IIEF at baseline. Descriptive statistics was used to detail the entire cohort characteristics. Linear regression models were applied to explore the changes in patterns of sociodemographic and clinical character
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