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Journal articles on the topic '612.1121 20'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 January 2023

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1

Uccelli, Raffaella, Alberto Calugi, Donato Forte, et al. "Flow Cytometrically Determined DNA Content of Breast Carcinoma and Benign Lesions: Correlations with Histopathological Parameters." Tumori Journal 72, no. 2 (1986): 171–77. http://dx.doi.org/10.1177/030089168607200209.

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The relative DNA content of cellular samples from 54 patients affected by breast carcinomas and 20 affected by benign breast lesions (including 11 fibroadenomas) was measured by flow cytometry. All normal tissue samples and 17/20 (85%) specimens from benign lesions exhibited a cytometrically diploid DNA distribution, 3/20 (15%) benign lesions an abnormal DNA content, and 35/54 (65%) carcinomas at least one aneuploid cell subpopulation. Furthermore, 9/54 (17%) tumors were characterized by the presence of more than one aneuploid cell subpopulation. The results also indicate that flow cytometry c

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López Salguero, S., M. Andres, P. Vela-Casasempere, et al. "THU0354 CHARACTERIZATION OF ANTI-MYOSITIS ANTIBODY RELATED MYOPATHIES. DESCRIPTIVE STUDY IN A MULTICENTRIC COHORT." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 408.2–408. http://dx.doi.org/10.1136/annrheumdis-2020-eular.6125.

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Background:Idiopathic inflammatory myopathies (IIM) are a group of rare diseases consisting on immune-mediated muscle damage. About 40 to 60% show specific-myositis antibodies; aditionally, 20-40% can show myositis-related (non-specific) antibodies. The profile of antibodies can help to divide patients into subgroups with more homogeneous clinical characteristics and prognosis.Objectives:This study characterizes patients with IIM with specific or related anti-myositis antibodies, in five hospitals in the Alicante health area.Methods:This is an observational study, carried out in five hospitals

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Pegu, Bhabani, and Bhanu Pratap Singh Gaur. "Elderly primigravida and a comparative analysis of their pregnancy outcome with younger primigravida." International Journal of Research in Medical Sciences 6, no. 11 (2018): 3478. http://dx.doi.org/10.18203/2320-6012.ijrms20184402.

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Background: Though pregnancy and child birth is a normal physiological process but a woman with advanced age is a risk factor for adverse pregnancy outcome. This study was conducted to find out the proportion of elderly primigravida and to compare their pregnancy outcome with that in younger primigravida of aged 20-25yrs.Methods: A retrospective study was carried out over a period of two years in a tertiary care hospital of Meghalaya. Secondary data on obstetrics outcome of 54 elderly primigravida aged ≥35 years (study group) was compared to 120 younger primigravida (control group) of aged 20-

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Fernandez-Rodriguez, Beatriz, Ana Roche Gomez, Blanca Sofia Jimenez Moreno, et al. "Smoking influence on early and late fetal growth." Journal of Perinatal Medicine 50, no. 2 (2021): 200–206. http://dx.doi.org/10.1515/jpm-2021-0226.

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Abstract Objectives Smoking during pregnancy is a leading and modifiable risk factor for fetal growth restriction (FGR) and low birthweight (<10th centile). We studied the effects of smoking in the development of early and late FGR or low birthweight, as well as in uteroplacental and fetoplacental hemodynamics of growth-restricted fetuses. Methods Retrospective cohort study of 5,537 consecutive singleton pregnancies delivered at ≤34 + 0 (“early delivery” group, n=95) and >34 + 0 (“late delivery” group, n=5,442) weeks of gestation. Each group was divided into smokers and non-smokers. Pren

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CABEDO, L., L. PICART i BARROT, and A. TEIXIDÓ i CANELLES. "Prevalence of Listeria monocytogenes and Salmonella in Ready-to-Eat Food in Catalonia, Spain." Journal of Food Protection 71, no. 4 (2008): 855–59. http://dx.doi.org/10.4315/0362-028x-71.4.855.

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Listeria monocytogenes and Salmonella are pathogenic bacteria that can contaminate food products during or after processing. Ready-to-eat (RTE) food does not undergo any treatment to ensure its safety before consumption, and therefore risk of foodborne disease must be considered if these pathogens are present in the food. To evaluate the prevalence of these pathogens in RTE food, 140 RTE fish product samples, 501 RTE meat product samples, 462 RTE dairy samples, and 123 RTE dishes and desserts, providing a total of 1,226 samples, were collected from retail stores and food industry and analyzed

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Arslan, Fatih, Emre Aydemir, Yavuz Selim Kaya, Hasan Arslan, and Abdullah Durmaz. "Anxiety and Depression in Patients with Sudden One-sided Hearing Loss." Ear, Nose & Throat Journal 97, no. 10-11 (2018): E7—E9. http://dx.doi.org/10.1177/0145561318097010-1101.

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Sudden sensorineural hearing loss is a hearing loss of >30 dB in at least three consecutive frequencies that occurs in 3 days. The aim of this study was to investigate anxiety and depression caused by sudden, idiopathic, one-sided hearing loss. The levels of anxiety and depression in patients with this type of hearing loss were determined using the Beck Anxiety Scale (BAS) and the Beck Depression Inventory (BDI) at the time of the patient's first visit. In total, 56 patients (32 men and 24 women) with a mean age of 32.8 ± 9.9 years (range: 20 to 58 years) were selected as the patient group

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Najmah, Indah Purnama Sari, Tri Novia Kumalasari, and Sharyn Graham Davies. "FACTORS INFLUENCING HIV KNOWLEDGE AMONG WOMEN OF CHILDBEARING AGE IN SOUTH SUMATRA, INDONESIA." Malaysian Journal of Public Health Medicine 20, no. 1 (2020): 150–59. http://dx.doi.org/10.37268/mjphm/vol.20/no.1/art.552.

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This study aims to provide detailed information on the role of the following social determinants (i.e. education, occupation, place of residence, marital and economic status) in the acquisition of HIV knowledge among women of childbearing age (15-49 years old). The study uses secondary data from the 2012 Indonesian Demographic and Health Survey (IDHS). The IDHS used a quantitative analytical approach with a cross-sectional study design and multi-stage stratified sampling. The sample included 1,335 women aged 15 to 49 years old living in South Sumatra Province, Indonesia. Descriptive analysis,

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Kulkarni, Smita S., Jayshree B. Bhakre, and Ajit S. Damle. "In vitro susceptibility testing of four antifungal drugs against fungal isolates in onychomycosis." International Journal of Research in Medical Sciences 6, no. 8 (2018): 2774. http://dx.doi.org/10.18203/2320-6012.ijrms20183268.

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Background: Onychomycosis is chronic fungal infection of fingernails and toenails. Variety of fungi cause onychomycosis. Due to importance of high prevalence rate of onychomycosis this study was conducted.Methods: In this study 100 patients suspected of onychomycosis were examined. Diagnosis of onychomycosis was based on the patient’s history, physical examination, microscopy and culture of nail specimens.Results: Direct microscopy of the nail clippings in 20% KOH solution was positive in 61% and culture was positive in 54% cases. The common etiological agent was dermatophytes (79.6% cases) fo

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Liotta, Mark, Peter Cangialosi, Jeanne Ho, Diana Finkel, Shobha Swaminathan, and Steven Keller. "615. Overlooking those at Intermediate Risk? ASCVD Prevention Measures among People Living with HIV at an Urban Academic Medical Center." Open Forum Infectious Diseases 7, Supplement_1 (2020): S367—S368. http://dx.doi.org/10.1093/ofid/ofaa439.809.

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Abstract Background The American College of Cardiology (ACC) recognizes HIV as a risk factor for atherosclerotic cardiovascular disease (ASCVD). However, 2019 guidelines do not address people living with HIV (PLWH), aside from stating that their Risk Estimator Plus tool, which is used to calculate a 10-year risk for ASCVD and advise management, likely underestimates CVD risk in PLWH. This quality assessment project examines rates of ACC guideline adherence for ASCVD prevention for PLWH who have calculated risk scores in the low (&lt; 7.5%), intermediate (&gt; 7.5% & &lt; 20%),

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Sezgin, Gulbuz, Guler Ozturk, Rana Turkal, and Burcu Caykara. "Vitamin D levels of outpatients admitted to a university hospital in the marmara region of Turkey over 3 years." Journal of Medical Biochemistry 38, no. 2 (2019): 181–87. http://dx.doi.org/10.2478/jomb-2018-0027.

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SummaryBackgroundVitamin D regulates calcium and phosphorus metabolism, and it is essential for bone formation. Several factors can affect vitamin D levels in plasma. In present study we compare vitamin D levels of outpatients, who admit to Maltepe University Hospital between 2011 and 2013 and had vitamin D measurements regarding gender, age, and season.MethodsHospital records were evaluated to identify the outpatients with vitamin D levels and their gender, age, and vitamin D levels and the seasons of measurements were recorded.ResultsData of 4860 subjects (74% female) were analyzed and 69.2%

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Cruciani, Décio E., Ronalton E. Machado, and Paulo C. Sentelhas. "Modelos da distribuição temporal de chuvas intensas em Piracicaba, SP." Revista Brasileira de Engenharia Agrícola e Ambiental 6, no. 1 (2002): 76–82. http://dx.doi.org/10.1590/s1415-43662002000100014.

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O estudo da variação temporal de chuvas intensas é de grande importância na hidrologia, para a análise e previsão de eventos extremos, necessárias em projetos de controle de engenharia. Com esse objetivo, foram analisados dados de pluviogramas da cidade de Piracicaba, SP, do período de 1966 a 2000, para se determinar a distribuição temporal de chuvas intensas de 60 e de 120 min de duração. As chuvas de 60 min foram subdivididas em três intervalos iguais e sucessivos de 20 min cada um, enquanto as chuvas de 120 min foram subdivididas em quatro intervalos iguais e sucessivos de 30 min cada um. O

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Jumbo, Caroline H., Rafat B. Muhammad, Nathaniel D. Adewole, Dennis A. Isah, Richard A. Offiong, and Habiba I. Abdullahi. "Uptake of long-acting reversible contraceptives in north central Nigeria: a five-year review." International Journal of Research in Medical Sciences 9, no. 5 (2021): 1335. http://dx.doi.org/10.18203/2320-6012.ijrms20211866.

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Background: Long-acting reversible contraceptives (LARC) are methods used in the prevention of pregnancy that are long lasting. They are effective and efficacious methods of contraception and return to fertility after removal is prompt. Objectives was to determine the uptake of long-acting reversible contraception and assess the characteristics of acceptors of these methods in the area.Methods: This was a retrospective study of clients’ who visited the family planning unit of the University of Abuja teaching hospital over a 5-year period, from 01 January 2015 to 31 December 2019. Information o

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Ayogu, Malachy Emeka, Kate Ifeoma Omonua, Kate Ifeoma Omonua, Miriam Chinelo Ayogu, and Miriam Chinelo Ayogu. "Eclampsia at the university of Abuja teaching hospital: a ten-year review." International Journal of Research in Medical Sciences 7, no. 10 (2019): 3767. http://dx.doi.org/10.18203/2320-6012.ijrms20194307.

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Background: Worldwide, eclampsia remains one of the major causes of maternal and perinatal morbidity and mortality. Pre-eclampsia/eclampsia is a multisystem disease and despite extensive research, no definitive etiology has been identified. This disease therefore continues to pose a challenge in obstetric practice, especially in developing countries like ours. We therefore set out to determine the prevalence, associated factors, and outcome of eclampsia at the University of Abuja Teaching Hospital, Abuja, Nigeria.Methods: A descriptive retrospective review of cases of eclampsia managed at the

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Nyambura Njuguna, Adele, John Maina Kagira, Simon Muturi Karanja, Maina Ngotho, Lucy Mutharia, and Naomi Wangari Maina. "Prevalence ofToxoplasma gondiiand Other Gastrointestinal Parasites in Domestic Cats from Households in Thika Region, Kenya." BioMed Research International 2017 (2017): 1–6. http://dx.doi.org/10.1155/2017/7615810.

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Gastrointestinal (GIT) parasites of domestic cats (Felis catus) not only cause morbidity but are also potential zoonotic agents. The current study aimed at establishing the prevalence of GIT parasites in cats kept by households in Thika region, Kenya. Fecal samples were collected randomly from 103 cats and analyzed for presence of parasites using standard parasitological methods. In descending order, the prevalence of the detected protozoa parasites wasIsosporaspp. 43.7% (95% CI: 40.4–47%),Cryptosporidiumspp. 40.8% (95% CI: 37.5–44.1%),Toxoplasma gondii7.8% (95% CI: 4.5–11.1%), andEntamoebaspp

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Ye, Sheng-Lin, Chuang Wang, Lu-Lu Wang, Tian-Ze Xu, Xiao-Qiang Li, and Tao Tang. "Oral Anticoagulant and Antiplatelet Therapy for Cervical Artery Dissection: A Meta-Analysis of Clinical Trials." Clinical and Applied Thrombosis/Hemostasis 27 (January 2021): 107602962110517. http://dx.doi.org/10.1177/10760296211051708.

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Carotid and vertebral artery dissections are estimated to account for ∼20% of strokes in patients under 45-years-old. This meta-analysis compared the efficacy and safety of treatment with anticoagulants versus antiplatelet agents to determine the optimal therapy. We searched 4 electronic databases for clinical trials published from January 1, 1980 to August 25, 2021 that included patients who received anticoagulant or antiplatelet therapy for carotid and/or vertebral artery dissections. The curative effect was judged by recanalization evaluated by imaging. The primary outcomes were all cause d

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Joueidi, Yolaine, Ludivine Dion, Sofiane Bendifallah, et al. "Management and Survival of Elderly and Very Elderly Patients with Ovarian Cancer: An Age-Stratified Study of 1123 Women from the FRANCOGYN Group." Journal of Clinical Medicine 9, no. 5 (2020): 1451. http://dx.doi.org/10.3390/jcm9051451.

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Elderly women with ovarian cancer are often undertreated due to a perception of frailty. We aimed to evaluate the management of young, elderly and very elderly patients and its impact on survival in a retrospective multicenter study of women with ovarian cancer between 2007 to 2015. We included 979 women: 615 women (62.8%) <65 years, 225 (22.6%) 65–74 years, and 139 (14.2%) ≥75 years. Women in the 65–74 years age group were more likely to have serous ovarian cancer (p = 0.048). Patients >65 years had more >IIa FIGO stage: 76% for <65 years, 84% for 65–74 years and 80% for ≥75 years

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John, Stanley, Colin John, Kamales Saha, Bashi Velayudhan Velaikodeth, and Edwin Ravikumar. "A Quarter Century Experience with Mitral Valve Replacement." Asian Cardiovascular and Thoracic Annals 4, no. 4 (1996): 201–5. http://dx.doi.org/10.1177/021849239600400403.

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Between January 1967 and August 1994 Starr-Edwards (Baxter Healthcare Corporation, Santa Ana, CA, USA) ball valve prostheses (model 6120) were implanted in 1129 patients whose ages ranged from 9 to 65 years (mean 29.5 ± 11.08 years). One hundred and ninety-three patients had a concomitant tricuspid valve repair and 36 underwent closure of an atrial septal defect. A closed mitral valvotomy had been carried out previously in 15%. The hospital (30-day) mortality rate was 10.9% (123/1129), which declined to 6.9% (32/461) in the last decade. The patients were administered warfarin to counter thromb

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Zhuikova, L. D., E. L. Choynzonov, O. A. Ananina, A. S. Zhuikova, and T. V. Polychuk. "ASSESSMENT OF SOCIAL AND ECONOMIC DAMAGE ASSOCIATED WITH MORTALITY FROM RESPIRATORY CANCER IN THE TOMSK REGION (2005–2016)." Siberian journal of oncology 20, no. 4 (2021): 21–29. http://dx.doi.org/10.21294/1814-4861-2021-20-4-21-29.

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Introduction. A significant component in the system analysis of anti-cancer activities is the assessment of the impact of mortality on life expectancy, which indicates the social and economic situation in the region.Material and methods. The economic damage caused by laryngeal and lung cancer mortality in the Tomsk region for the period 2005–2016 was analyzed using the database of the regional cancer registry and local agency of federal state statistics service of the tomsk region.Results. The loss of the male working population ranged from 106.0 (2012–2013) to 161.5 (2008–2009) person/years o

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Allen, RN, EB Dettmann, GG Johns, and DW Turner. "Estimation of leaf emergence rates of bananas." Australian Journal of Agricultural Research 39, no. 1 (1988): 53. http://dx.doi.org/10.1071/ar9880053.

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Leaf emergence rates (LER, leaves/day) of 17 AAA genome banana cultivars (Musa sp., subgroups Gros Michel, Cavendish, Red/Green-red) were estimated using a model based on mean monthly air temperature (13.3-27.9�C), daylength (10.2-13.8 h day), age of planting (48-1361 days), plant density (1111-2222 mats/ha) and cultivar stature (0.88-4.15 m). The LER model involved the five factors in a multiplicative form and was developed initially for one set of 612 observations on all 17 cultivars at Alstonville, N.S.W. but at one density only. The model indicated that LER increased with increasing temper

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Shardell, Michelle, Anne R. Cappola, Jack M. Guralnik, et al. "Sex-specific 25-hydroxyvitamin D threshold concentrations for functional outcomes in older adults: PRoject on Optimal VItamin D in Older adults (PROVIDO)." American Journal of Clinical Nutrition 114, no. 1 (2021): 16–28. http://dx.doi.org/10.1093/ajcn/nqab025.

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ABSTRACT Background Threshold serum 25-hydroxyvitamin D [25(OH)D] concentrations for extraskeletal outcomes are uncertain and could differ from recommendations (20–30 ng/mL) for skeletal health. Objectives We aimed to identify and validate sex-specific threshold 25(OH)D concentrations for older adults’ physical function. Methods Using 5 large prospective, population-based studies—Age, Gene/Environment Susceptibility-Reykjavik (n = 4858, Iceland); Health, Aging, and Body Composition (n = 2494, United States); Invecchiare in Chianti (n = 873, Italy); Osteoporotic Fractures in Men (n = 2301, Unit

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Philip, Philip Agop, Marc E. Buyse, Angela Tatiana Alistar, et al. "Avenger 500, a phase III open-label randomized trial of the combination of CPI-613 with modified FOLFIRINOX (mFFX) versus FOLFIRINOX (FFX) in patients with metastatic adenocarcinoma of the pancreas." Journal of Clinical Oncology 37, no. 4_suppl (2019): TPS479. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.tps479.

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TPS479 Background: Metastatic pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers. Current treatments using FOLFIRINOX and gemcitabine plus nab-paclitaxel, provide median survivals of 11.1 and 8.5 months, respectively. PDAC cells have altered metabolism. CPI-613 is a novel TCA cycle inhibitor that targets cancer cells. In a phase I study mFFX plus CPI-613 resulted in a 61% objective response rate with 3 of 18 patients achieving a complete response. Methods: Avenger 500 (NCT03504423) is an open-label randomized trial of CPI-613 plus mFFX versus FFX in untreated patients with

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Haefliger, Ivan O., Yasmina D. Haefliger, and Ana Rosa Pimentel de Figueiredo. "A PubMed Citations Search Study on the Prevalence of Epiphora in the General Adult Population." Klinische Monatsblätter für Augenheilkunde 237, no. 04 (2020): 527–30. http://dx.doi.org/10.1055/a-1112-7335.

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Abstract Purpose To assess the prevalence of epiphora in the general adult population based on PubMed search citations. Methods 1) Electronic PubMed MEDLINE database search (September 13, 2019) with the terms (Medical Subject Headings or MeSH) “prevalence” and “epiphora”, 2) “epiphora” and “dry eye”, and 3) “prevalence”, “epiphora”, and “dry eye”. Review of all citations from these searches containing the term “epiphora” either in their abstract or title. Results 1) PubMed search retrieved 2 617 137 citations for “prevalence”, 26 135 for “epiphora”, and 2554 for “prevalence” AND “epiphora”. Wi

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Sunakawa, Yu, Wataru Ichikawa, Akihito Tsuji, et al. "Prognostic impact of primary tumor location on survival time in patients (pts) with metastatic colorectal cancer (mCRC) treated with cetuximab plus oxaliplatin-based chemotherapy: A subgroup analysis of the JACCRO CC-05/06." Journal of Clinical Oncology 34, no. 4_suppl (2016): 613. http://dx.doi.org/10.1200/jco.2016.34.4_suppl.613.

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613 Background: Sub-analyses of US and European randomized trials have demonstrated that primary tumor location is a critical prognostic factor in mCRC treated with 1st-line chemotherapy; moreover, left-sided tumor location may be a predictor of cetuximab efficacy in KRAS exon 2 wild-type tumors (Loupakis F, et al. J Natl Cancer Inst 2015; von Einem JC, et al. J Cancer Res Clin Oncol 2014). We therefore investigated the prognostic impact of primary tumor location on outcomes of Japanese pts enrolled in JACCRO CC-05 or CC-06 trial, which evaluated efficacy of cetuximab in combination with FOLFO

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Yamaguchi, Tatsuro, Akihito Tsuji, Yu Sunakawa, et al. "A phase II study of cetuximab (cet) and mFOLFOX6 in metastatic colorectal cancer (mCRC) (JACCRO CC-05)." Journal of Clinical Oncology 32, no. 3_suppl (2014): 611. http://dx.doi.org/10.1200/jco.2014.32.3_suppl.611.

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611 Background: FOLFOX4 combined with cet for mCRC patients (pts) with KRAS wild tumor demonstrated the prolonged progression-free survival (PFS) with higher response rate (RR) in the OPUS study. To evaluate the clinical efficacy and safety of the cet plus mFOLFOX6, we conducted a multi-center phase II study of Japanese pts. Methods: In this trial, pts with KRAS wild type tumor and receiving no prior chemotherapy for mCRC were treated with cet (initial dose 400, and 250 mg/m2 weekly) followed by mFOLFOX6 (oxaliplatin 85mg/m2, l-leucovorin 200 mg/m2, fluorouracil, as 400mg/m2 intravenous bolus

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Tomlins, Jo, Nick Telford, Mike Dennis, et al. "Population Based Study of Cytogenetic Abnormalities in Addition to Philadelphia (Ph) Chromosome in Patients with Chronic Myeloid Leukaemia (CML) and Impact on Survival." Blood 124, no. 21 (2014): 4567. http://dx.doi.org/10.1182/blood.v124.21.4567.4567.

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Abstract Ph chromosome is the hallmark of CML. However there are few reports of additional chromosomal abnormalities at the time of diagnosis and the impact this has on overall survival (OS). [NT1] The Cytogenetic laboratory at this hospital provides a regional service as a single facility. The data from this laboratory was combined with survival information to evaluate the impact of additional chromosomal changes on outcomes in patients with CML. Methods: This is a retrospective population based study, it was not possible to obtain consent from individual patients and details about haematolog

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Palmieri, Carolina, Mona Simões, Jean Silva, Anelise Santos, Mariana Silva, and Bruna Ferreira. "Prevalence of Hypertrophic Cardiomyopathy in Fetuses of Mothers with Gestational Diabetes before Initiating Treatment." Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics 39, no. 01 (2017): 09–13. http://dx.doi.org/10.1055/s-0037-1598602.

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Objective To evaluate the prevalence of hypertrophic cardiomyopathy (HCM) in fetuses of pregnant women with gestational diabetes mellitus (GDM) in the beginning of the treatment. Methods A cross-sectional study was performed between July 1, 2013, and December 20, 2013, in a public maternity clinic in southern Brazil. The subjects were 63 fetuses of mothers with gestational diabetes, with a single pregnancy and no other associated pathologies. We diagnosed HCM through a fetal echocardiography before treatment and evaluated the maternal and fetal characteristics. Results The average age of the p

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Rudolph, Karen, Michael G. Bruce, Dana Bruden, et al. "Epidemiology of Invasive Group A Streptococcal Disease in Alaska, 2001 to 2013." Journal of Clinical Microbiology 54, no. 1 (2015): 134–41. http://dx.doi.org/10.1128/jcm.02122-15.

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The Arctic Investigations Program (AIP) began surveillance for invasive group A streptococcal (GAS) infections in Alaska in 2000 as part of the invasive bacterial diseases population-based laboratory surveillance program. Between 2001 and 2013, there were 516 cases of GAS infection reported, for an overall annual incidence of 5.8 cases per 100,000 persons with 56 deaths (case fatality rate, 10.7%). Of the 516 confirmed cases of invasive GAS infection, 422 (82%) had isolates available for laboratory analysis. All isolates were susceptible to penicillin, cefotaxime, and levofloxacin. Resistance

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Mishra, Trinath, and Rainer Pöttgen. "Intermetallic REPtZn Compounds with TiNiSi-type Structure." Zeitschrift für Naturforschung B 66, no. 7 (2011): 671–76. http://dx.doi.org/10.1515/znb-2011-0703.

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The equiatomic rare earth compounds REPtZn (RE = Y, Pr, Nd, Gd-Tm) were synthesized from the elements in sealed tantalum tubes by high-frequency melting at 1500 K followed by annealing at 1120 K and quenching. The samples were characterized by powder X-ray diffraction. The structures of four crystals were refined from single-crystal diffractometer data: TiNiSi type, Pnma, a = 707.1(1), b = 430.0(1), c = 812.4(1) pm, wR2 = 0.066, 602 F2, 21 variables for PrPt1.056Zn0.944; a = 695.2(1), b = 419.9(1), c = 804.8(1) pm, wR2 = 0.041, 522 F2, 21 variables for GdPt0.941Zn1.059; a = 688.2(1), b = 408.1

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García, O., S. Camarero, J. F. Colom, et al. "Optimization of a Laccase-Mediator Stage for TCF Bleaching of Flax Pulp." Holzforschung 57, no. 5 (2003): 513–19. http://dx.doi.org/10.1515/hf.2003.076.

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SummaryFlax pulp obtained by anthraquinone-soda pulping, resulting in a kappa number of 11.1, a viscosity of 950 ml/g and 36.7% ISO brightness, was bleached in a totally chlorine-free sequence using the enzyme laccase from the fungusPycnoporus cinnabarinusand 1-hydroxybenzotriazole (HBT) as redox mediator (stage L), followed by a hydrogen peroxide stage (P). The laccase treatment was optimized using a three-variable sequential statistical plan over the following ranges: 1–20 U/g o.d.p. (oven-dried pulp) laccase dose, 0.5–7.5% o.d.p. HBT dose and 1–24 h reaction time. The influence of these var

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Beals, J. M., та F. J. Castellino. "The interaction of bovine factor IX, its activation intermediate, factor IX α, and its activation products, factor IXaα and factor IXaβ, with acidic phospholipid vesicles of various compositions". Biochemical Journal 236, № 3 (1986): 861–69. http://dx.doi.org/10.1042/bj2360861.

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The interactions of bovine factor IX, its activation intermediate, Factor IX alpha, and its activation products, Factor IXa alpha and Factor IXa beta, with phospholipid vesicles, of mean radius of approx. 30 nm, containing various amounts of phosphatidylserine (PS) and phosphatidylcholine (PC), have been examined. For Factor IX, Factor IX alpha, Factor IXa alpha and Factor IXa beta, the dissociation constants, at saturating levels of Ca2+, are independent of the PS concentration in the vesicle after levels of 20-30% (w/w) have been reached, and attain minimum values of approx. 1.7, 1.7, 0.7 an

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Hassan, Raffit, Anish Thomas, John J. Nemunaitis, et al. "Avelumab in patients with previously treated mesothelioma: Updated phase 1b results from the JAVELIN Solid Tumor trial." Journal of Clinical Oncology 36, no. 5_suppl (2018): 166. http://dx.doi.org/10.1200/jco.2018.36.5_suppl.166.

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166 Background: Avelumab, a human anti-PD-L1 IgG1 monoclonal antibody, is approved for treatment of metastatic Merkel cell carcinoma (US and EU) and advanced urothelial carcinoma progressed on platinum therapy (US). Here, we report updated phase 1b data for avelumab in patients (pts) with previously treated mesothelioma. Methods: Pts with unresectable pleural or peritoneal mesothelioma whose disease had progressed after platinum and pemetrexed therapy received avelumab 10 mg/kg IV Q2W until progression, unacceptable toxicity, or withdrawal. Tumors were assessed every 6 wks (RECIST 1.1). Endpoi

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Sadjadi, SeyedAbdolreza, Quentin Andrew Parker, Chih-Hao Hsia, and Yong Zhang. "A Theoretical Study of Infrared Spectra of Highly Positively Charged C₆₀ Fullerenes and Their Relevance to Observed UIE Features." Astrophysical Journal 934, no. 1 (2022): 75. http://dx.doi.org/10.3847/1538-4357/ac75d5.

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Abstract By applying first principles quantum chemical calculations, we present a complete catalog of the theoretically expected mid-infrared signatures of cationic forms of fullerene with the general formula of C 60 q + (q = 1–26). The structural stability and bonding of these exotic species have been reported by us elsewhere. It is found that not only can some of these cations contribute significantly to the flux of the 17.4 and 18.9 μm bands of fullerene that are observed in some planetary nebulae but they also show strong bands that match the position of key astronomical unidentified infra

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Lin, Z. Q., W. H. Hendershot, P. H. Schuepp, G. G. Kennedy, and P. Dutilleul. "Total elements in forest soils affected by acid deposition in southern Quebec." Canadian Journal of Soil Science 76, no. 2 (1996): 165–71. http://dx.doi.org/10.4141/cjss96-023.

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Major and trace elements (Al, As, Ba, Ca, Cd Co, Cr Cs, Cu Eu Fe, Hf, K, La, Lu, Mg, Mn, Na, Ni, Pb, Rb, Sb, Sc, Si, Sm, Sr, Ta, Tb, Th, Ti, U, V, Yb and Zn) in forest soils from three acid-deposition-affected locations in southern Quebec were investigated. Total element concentrations in the surface layer (0–20 cm) of the Podzolic soils were mostly well within the range of element concentrations in Podzols reported worldwide but showed higher mean values for most elements. The mean concentrations of elements (except Zn, at 124 μg g−1) were also generally comparable to the respective elemental

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Conteduca, Vincenza, Clara Oromendia, Panagiotis J. Vlachostergios, et al. "Clinical and molecular analysis of patients treated with prostate-specific membrane antigen (PSMA)-targeted radionuclide therapy." Journal of Clinical Oncology 37, no. 7_suppl (2019): 272. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.272.

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272 Background: PSMA targeted therapy has recently emerged as a promising approach for patients with advanced prostate cancer. However, there is still a need for reliable biomarkers that provide information about clinically meaningful outcomes and treatment responses. Methods: Baseline, treatment and outcomes data along with tumor whole-exome sequencing (WES) data were retrospectively evaluated in anti-PSMA-treated patients (pts). Statistical comparisons utilized Cox regression analysis and Kaplan-Meier method for association with overall/progression-free/survival (OS/PFS) and PSA response. Re

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Sampath, Perumal, and Tae-Jin Yang. "Comparative analysis of Cassandra TRIMs in three Brassicaceae genomes." Plant Genetic Resources 12, S1 (2014): S146—S150. http://dx.doi.org/10.1017/s1479262114000446.

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Terminal-repeat retrotransposon in miniature (TRIM) elements are a miniature form of retrotransposons and play an important role in genome organization. The Cassandra TRIM family has been identified in over 50 plant species, including both monocots and dicots. Cassandra elements carry an independently transcribed 5S RNA sequence in their terminal repeat regions, which is unique compared with other TRIM families. Although the existence of Cassandra elements has been documented in many plants, much work remains to characterize Cassandra family members and elucidate their distribution. In this st

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JPT staff, _. "E&P Notes (November 2021)." Journal of Petroleum Technology 73, no. 11 (2021): 14–16. http://dx.doi.org/10.2118/1121-0014-jpt.

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TotalEnergies Drills Dry Hole Offshore Suriname TotalEnergies has plugged and abandoned its Keskesi South-1 on Block 58 offshore Suriname after encountering noncommercial quantities of hydrocarbons. Keskesi South-1 was drilled about 6.2 km from the discovery well Keskesi East-1. “The first appraisal well at Keskesi was a substantial stepout designed to assess the southern extent of the feature,” said Tracey K. Henderson, senior vice president, exploration at APA, a partner in the block. “This location had the potential to confirm a very large resource in place if connected to the reservoir san

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Hoppe, Matthias Wilhelm, Christian Baumgart, Mirko Slomka, Ted Polglaze, and Jürgen Freiwald. "Variability of Metabolic Power Data in Elite Soccer Players During Pre-Season Matches." Journal of Human Kinetics 58, no. 1 (2017): 233–45. http://dx.doi.org/10.1515/hukin-2017-0083.

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Abstract This study aimed to determine the within-subject variability of GPS-derived metabolic power data in elite soccer players across several pre-season matches and compare the variability of high metabolic power, velocity, acceleration and deceleration running. Additionally, differences in metabolic power data among playing positions and relationships with various physical abilities were also investigated. Metabolic power data from 12 outfield starting players competing in the German Bundesliga were collected during five pre-season matches using GPS-technology (10 Hz). The players were als

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Jennings, Denise, Stuart Cormack, Aaron J. Coutts, Luke J. Boyd, and Robert J. Aughey. "Variability of GPS Units for Measuring Distance in Team Sport Movements." International Journal of Sports Physiology and Performance 5, no. 4 (2010): 565–69. http://dx.doi.org/10.1123/ijspp.5.4.565.

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Purpose:To examine the difference in distance measured by two global positioning system (GPS) units of the same model worn by the same player while performing movements common to team sports.Methods:Twenty elite Australian football players completed two trials of the straight line movement (10, 20, 40 m) at four speeds (walk, jog, stride, sprint), two trials of the changes of direction (COD) courses of two different frequencies (gradual and tight), and five trials of a team sport running simulation circuit. To assess inter-unit variability for total and high intensity running (HIR) distance me

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Tenerowicz-Zaba, M., M. Kupkova, M. Kabatova, E. Dudrova, M. Dzupon, and M. Sulowski. "Density, Microstructure, Strength and Fractography of Spark Plasma and Conventionally Sintered Mn Steels." Powder Metallurgy Progress 17, no. 2 (2017): 93–103. http://dx.doi.org/10.1515/pmp-2017-0010.

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Abstract The aim of the study was to investigate Spark Plasma Sintering (SPS) of 1-3%Mn steels and compare the resultant microstructures, strengths and failure mechanisms with those of conventionally sintered materials. SPS was performed in a vacuum of 5 Pa at 1000°C for 15min under a uniaxial pressure of 20 MPa. The heating rate of 100°C/min was applied. For conventional processing, mixtures of powders were prepared in a Turbula mixer for 30 minutes. Samples were single pressed at 660 MPa, according to PN-EN ISO 2740 standard. Sintering of compacts was carried out in a laboratory tube furnace

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Nardi, Valentina, Federico Franchi, Megha Prasad, et al. "Uric Acid Expression in Carotid Atherosclerotic Plaque and Serum Uric Acid Are Associated With Cerebrovascular Events." Hypertension 79, no. 8 (2022): 1814–23. http://dx.doi.org/10.1161/hypertensionaha.122.19247.

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Background: Uric acid (UA) concentration within carotid plaque and its association with cerebrovascular events have not been detected or quantified. Systemically, serum UA is a marker of inflammation and risk factor for atherosclerosis. However, its association with carotid plaque instability and stroke pathogenesis remains unclear. In patients undergoing carotid endarterectomy, we aimed to determine whether UA is present differentially in symptomatic versus asymptomatic carotid plaques and whether serum UA is associated with cerebrovascular symptoms (stroke, transient ischemic attack, or amau

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Xu, Fei, Monique Gelderman-Fuhrmann, John Farrell, and Jaroslav Vostal. "Temperature Cycling Improves In Vivo recovery of Cold Stored Human Platelets." Blood 118, no. 21 (2011): 720. http://dx.doi.org/10.1182/blood.v118.21.720.720.

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Abstract Abstract 720 Platelets are currently limited to 5 days of storage at room temperature to prevent growth of bacteria to high levels. Cold storage of platelets could reduce bacterial proliferation but platelets stored in cold for over 48 hours are cleared rapidly from circulation through the hepatocyte Ashwell-Morell (AM) receptor thus limiting the applicability of cold temperatures to platelet storage. We used a temperature cycling method to store human platelets in the cold without decreasing their in vivo recovery in an immunodeficient (SCID) animal model of transfusion. Temperature

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Podzolkov, V. I., A. E. Bragina, and N. A. Druzhinina. "Relation of smoking and endothelial dysfunction markers in systemic hypertension." Cardiovascular Therapy and Prevention 17, no. 5 (2018): 11–16. http://dx.doi.org/10.15829/1728-8800-2018-5-11-16.

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Aim. Assessment of the markers levels of endothelial dysfunction (ED): stable metabolites of nitric oxide (NOx), endothelin-1 (E1), homocysteine (HC), von Willebrand factor (vWF) and tissue plasminogen activator (tPA) in blood plasma of smoker and nonsmoker patients with arterial hypertension (AH) of low and moderate risk, not taking antihypertension therapy regularly.Material and methods. Totally, 124 AH patients included, 45 males and 79 females, mean age 51,4±6,5 y.o., mean AH duration 7,9±7,3 y. Controls included 35 healthy volunteers (20 males, 15 females). Concentration of NOx in plasma

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Tušek, Ivan, Irina Pohodenko-Chudakova, Nikolaevna Tserakhava, et al. "Application of bio-resorbable membranes in preventing complications of lower jaw surgery." Balkan Journal of Dental Medicine 26, no. 1 (2022): 1–6. http://dx.doi.org/10.5937/bjdm2201001t.

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Background/Aim: Prevention of inflammation and alveolar bone atrophy is very important in oral surgery. The aim of this study was to compare the use of two osteoplastic bio-resorbable membranes in order to prevent inflammatory complications and atrophy of the alveolar part of the mandible after surgical interventions. Material and Methods: We examined 86 patients 45-70 years old who were classified into four groups. In group 1, there were 21 patients who had a "bio-resorbable membrane type 1 implanted. The group 2 consisted of 23 persons treated with bio-resorbable membrane type 2. Only the oc

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Tušek, Ivan, Irina Pohodenko-Chudakova, Nikolaevna Tserakhava, et al. "Application of bio-resorbable membranes in preventing complications of lower jaw surgery." Balkan Journal of Dental Medicine 26, no. 1 (2022): 1–6. http://dx.doi.org/10.2478/bjdm-2021-0031.

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Background/Aim: Prevention of inflammation and alveolar bone atrophy is very important in oral surgery. The aim of this study was to compare the use of two osteoplastic bio-resorbable membranes in order to prevent inflammatory complications and atrophy of the alveolar part of the mandible after surgical interventions. Material and Methods: We examined 86 patients 45-70 years old who were classified into four groups. In group 1, there were 21 patients who had a "bio-resorbable membrane type 1 implanted. The group 2 consisted of 23 persons treated with bio-resorbable membrane type 2. Only the oc

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Strasburger, Christian J., Anders Mattsson, Patrick Wilton, Ferah Aydin, Judith Hey-Hadavi, and Beverly M. K. Biller. "Increasing frequency of combination medical therapy in the treatment of acromegaly with the GH receptor antagonist pegvisomant." European Journal of Endocrinology 178, no. 4 (2018): 321–29. http://dx.doi.org/10.1530/eje-17-0996.

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Pegvisomant monotherapy is effective and safe in treatment of acromegaly. However, some clinicians combine pegvisomant with somatostatin analogues (SSA) or dopamine agonist (DA). In this analysis of ACROSTUDY, a long-term non-interventional study, the use of combination regimens was evaluated. Based on their baseline treatment, 2043 patients were retrospectively categorized as: long-acting SSA combined with pegvisomant, ‘Combo SSA’ 768 patients (38%); DA combined with pegvisomant, ‘Combo DA’ 123 (6%); pegvisomant monotherapy, ‘Peg mono’ 1128 (55%). Treatment patterns changed over the 10-year p

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Loginova, E. Yu, T. V. Korotaeva, E. E. Gubar, and S. I. Glukhova. "Prognostic factors associated with achieving minimal disease activity in early psoriatic arthritis patients treated according to “treat-to-target” st rategy within 12 months." Rheumatology Science and Practice 60, no. 6 (2022): 618–23. http://dx.doi.org/10.47360/1995-4484-2022-618-623.

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Background. The goal of “treat-to-target” strategy (T2T) in psoriatic arthritis (PsA) is attaining remission or minimal disease activity (MDA). The benefits of T2T are shown recently in the study TICOPA and REMARCA. But prognostic factors for achievement MDA in PsA patients (pts) at the early-stage hasn’t been studied yet.Objective – to determine the prognostic factors associated with achievement of minimal disease activity within 12 months (mo) of treatment according to T2T strategy in early psoriatic arthritis patients.Methods. 77 pts (M/F=36/41) with early PsA fulfilling the CASPAR criteria

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Ganju, Aruna, Uma V. Mahajan, Hanna Kemeny, H. Gregory Frankel, and Deborah L. Benzil. "Slow progress in the visibility of women in neurosurgery in the United States: opportunity for improvement." Neurosurgical Focus 50, no. 3 (2021): E10. http://dx.doi.org/10.3171/2020.12.focus20919.

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OBJECTIVEThe goal of this study was to analyze the visibility of women within organized neurosurgery, including leadership positions, lectureships, and honored guest/award recipients at neurosurgical conferences.METHODSA cross-sectional study was used to analyze the gender demographics within the five major national neurosurgical societies (Congress of Neurological Surgeons [CNS], American Association of Neurological Surgeons [AANS], Society of Neurological Surgeons [SNS], American Board of Neurological Surgery [ABNS], and Council of State Neurosurgical Societies [CSNS]) from 2000 to 2020. Dat

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Hussain, Syed A., Pablo Maroto, Miguel Ángel Climent, et al. "Targeting IGF-1/2 with xentuzumab (Xe) plus enzalutamide (En) in metastatic castration-resistant prostate cancer (mCRPC) after progression on docetaxel chemotherapy (DCt) and abiraterone (Abi): Randomized phase II trial results." Journal of Clinical Oncology 37, no. 15_suppl (2019): 5030. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.5030.

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5030 Background: Insulin-like growth factor receptor-1 (IGF-1R) signaling activates the PI3K/AKT pathway and may lead to androgen receptor (AR) transactivation and progression to endocrine treatment resistance. Xe, an IGF-ligand-neutralizing antibody, binds to IGF-1 and IGF-2 and inhibits IGF-1R signaling. This multi-center randomized phase II trial (NCT02204072) evaluated anti-tumor activity of Xe plus En in mCRPC. Methods: Men with histologically/cytologically confirmed mCRPC and progression after DCt+Abi were randomized to receive Xe 1000mg IV QW + En 160mg/day oral, or En alone (28-day cyc

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Samusenko, S. O., and I. V. Filatova. "MORBIDITY IN UKRAINIAN CHILDREN WITH DISEASES OF UPPER AIRWAYS, EAR AND PAPILLARY PROCESS: MODERN ASPECTS." International Medical Journal, no. 3 (September 16, 2020): 60–66. http://dx.doi.org/10.37436/2308-5274-2020-3-12.

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To determine the main trends in an incidence of childhood diseases of the upper airways, ear and papillary process, the data of the official state statistical information of the Ministry of Health of Ukraine were studied. The dynamics of prevalence and morbidity of children with these diseases in 2009−2017 were analyzed. An increase in the prevalence and incidence of respiratory diseases among the citizens and residents of rural areas by 26.8 % and 30.3 %, respectively, and a decrease in the above indices in urban children by 4.1 % and 3 % respectively were recorded. The incidence and prevalen

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Mal’tseva, A. N. "Effect of the COVID-19 infection on the menstrual function in women of reproductive age." Russian Journal of Woman and Child Health 5, no. 2 (2022): 112–17. http://dx.doi.org/10.32364/2618-8430-2022-5-2-112-117.

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Aim: to assess the effect of the COVID-19 infection on the menstrual function in women of reproductive age. Patients and Methods: the study group included 20 women who experienced COVID-19 and presented with menstrual disorders after infection. The study group was divided into two subgroups, i.e., women with mild (n=10) or severe (n=10) COVID-19 infection (subgroups 1 and 2, respectively). The control group included ten women without a history of COVID-19 infection and menstrual disorders. Hormone levels and hemostasis were evaluated, Doppler ultrasound (US) of basal and spiral arteries and ov

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