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1

Isaev, S., T. Rajabov, G. Goziev, and A. Khojasov. "Effect of fertilizer application on the ‘Bukhara-102’ variety of cotton yield in salt-affected cotton fields of Uzbekistan." E3S Web of Conferences 258 (2021): 03015. http://dx.doi.org/10.1051/e3sconf/202125803015.

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In this article, stratified feeding of Bukhara-102 variety of medium-fiber cotton with mineral fertilizers were carried out in the conditions of irrigated and fertile soils of Kashkadarya province. Simultaneously, compared to the studied fertilizer application options, there was a decrease in soil volume by 0.01–0.02 g/cm3, an increase in soil porosity by 0.4–1.2%, and an increase in soil water permeability to 5.8–24.6 m3/ha. Moreover, an additional yield of 1.3–2.6 quintals of cotton, the quality indicators of fiber length that increased by 0.1–0.2%, fiber yield to 0.2–0.5%, the weight of 1,
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2

Hussain, Ali. "Assessment of the water of the general estuary project for irrigation purposes through the study of the physical and chemical properties of the water and river deposits in the city of Nasiriyah and their comparison with the global determinants." Wasit Journal for Pure sciences 4, no. 1 (2025): 309–19. https://doi.org/10.31185/wjps.618.

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The study involved collecting samples from five stations located on the main river mouth to study their physical and chemical characteristics in order to assess their suitability for irrigation compared to international irrigation standards. Temperature, pH, electrical conductivity, total dissolved solids, and concentrations of calcium, magnesium, bicarbonates, chloride, nitrates, sulfates, phosphates, sodium, potassium, and lithium were measured. The results were as follows: temperature ranged from 32-33°C, pH ranged from 7.4-8.3, electrical conductivity ranged from 2620-2930µS/cm, total diss
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3

V.M, Vishwanath, and Ravishankar R.B. "A Clinical Comparative Study between Epidurally Administered Ropivacaine 0.2 % and Ropivacaine 0.2 % with Clonidine for Post-Operative Analgesia in Lower Limb and Abdominal Surgeries." Journal of Evidence Based Medicine and Healthcare 7, no. 50 (2020): 3010–15. http://dx.doi.org/10.18410/jebmh/2020/615.

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BACKGROUND There are many modalities to give postoperative analgesia. Out of them epidural analgesia offers good reliable pain relief. Addition of alpha agonist enhances the onset of analgesia and duration of analgesia is prolonged. This study was done to compare the analgesic efficacy, and the hemodynamic parameters of ropivacaine compared with ropivacaine in combination with clonidine for post-operative epidural analgesia. METHODS 30 patients of age 18 - 70 years with ASA grade of I & II, undergoing elective lower limb and abdominal surgeries were randomly taken into each of the 2 groups
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4

Ruder, Samuel Francis, Michael Philip Sun, Charlene Thomas, et al. "Comparison of adverse event rate of prostate-specific membrane antigen (PSMA)-targeted radionuclide therapy (TRT) with antibody or small molecule ligand targeting vector." Journal of Clinical Oncology 42, no. 4_suppl (2024): 161. http://dx.doi.org/10.1200/jco.2024.42.4_suppl.161.

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161 Background: PSMA-targeted radionuclide therapy (PSMA-TRT) has been established with use of either monoclonal antibodies (mAb) or small molecule ligands (SML) as the targeting vectors for delivery of 177Lu to PSMA-expressing prostate cancer. mAb and SML differ in their molecular weight, pharmacokinetics, and biodistribution which is predicted to result in different adverse effect profiles. Methods: In this study with written informed consent, we compare the adverse effects from individual patients receiving PSMA-TRT for mCRPC using mAb (J591) vs SML (PSMA-617 or PSMA I&T) for delivering
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5

Syraeva, G. I., A. S. Kolbin, S. A. Mishinova, and A. A. Kalyapin. "Quantitative and qualitative evaluation of the use of nonsteroidal anti-inflammatory drugs in the Russian Federation over 10 years." Kachestvennaya Klinicheskaya Praktika = Good Clinical Practice, no. 3 (November 14, 2022): 19–30. http://dx.doi.org/10.37489/2588-0519-2022-3-19-30.

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Relevance. Studies devoted to the assessment of consumption, as well as to the issues of pharmacosafety of nonsteroidal anti-inflammatory drugs, are limited at the national level in the Russian Federation. The study of these issues will determine the general trends of consumption and prescription of this group of drugs.Aim. To assess the consumption pattern of NSAIDs in the Russian Federation in the period from 2010 to 2020.Methods. Information was searched using data from the state register of drugs (GRLS) as well as national database downloads (automated information system of Roszdravnadzor;
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6

Sonbol, Mohamad Bassam, Raed Benkhadra, Zhen Wang, et al. "A systematic review and network meta-analysis of regorafenib and TAS-102 in refractory metastatic colorectal cancer." Journal of Clinical Oncology 37, no. 4_suppl (2019): 619. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.619.

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619 Background: Regorafenib (at a starting dose of 160 mg/day, rego 160), regorafenib (with a weekly dose escalation, rego 80+) and TAS-102, are suggested treatment options for refractory metastatic colorectal cancer (mCRC). We aimed to evaluate the comparative effectiveness evidence supporting these 3 strategies. Methods: We searched PubMed, Embase, and Cochrane CENTRAL, for randomized controlled trials evaluating TAS 102 or regorafenib in refractory mCRC patients who progressed on/intolerant of previous oxaliplatin, irinotecan, and fluoropyrimidine. Outcomes of interest included OS and PFS.
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7

Leznoff, Clifford C., Dmitri S. Terekhov, Colin R. McArthur, Steven Vigh, and Jing Li. "Multisubstituted phthalonitriles, naphthalenedicarbonitriles, and phenanthrenetetracarbonitriles as precursors for phthalocyanine syntheses." Canadian Journal of Chemistry 73, no. 3 (1995): 435–43. http://dx.doi.org/10.1139/v95-057.

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Electrophilic aromatic nitration under mild conditions of 4-hydroxyphthalonitrile gave 4-hydroxy-3-nitrophthalonitrile and 4-hydroxy-5-nitrophthalonitrile, while bromination yielded 3-bromo-4-hydroxyphthalonitrile, 4-bromo-5-hydroxyphthalonitrile, and 3,5-dibromo-4-hydroxyphthalonitrile. Iodination gave 4-hydroxy-5-iodophthalonitrile and 4-hydroxy-3,5-diidophthalonitrile. Coupling of 4-iodophthalonitrile, 3-iodophthalonitrile, and 5-iodo-2,3-dicyanonaphthalene with trans-1,2-bis(tri-n-butylstannyl)ethene gave trans-1,2-bis(3,4-dicyanophenyl)ethene, trans-1,2-bis(2,3-dicyanophenyl)ethene, and t
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8

Enginoev, Soslan T., Dmitriy A. Kondratiev, Gasan M. Magomedov, et al. "Effect of preoperative atrial fibrillation on long-term results after Off Pump Coronary Artery Bypass." Perm Medical Journal 38, no. 6 (2021): 5–15. http://dx.doi.org/10.17816/pmj3865-15.

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Objective. To study the effect of preoperative atrial fibrillation (AF) on the risk of stroke and long-term mortality after Off Pump Coronary Artery Bypass (OPCAB).
 Materials and methods. A retrospective analysis of the results of OPCAB in 212 patients with coronary artery disease (CAD), who were operated on from May 2009 to November 2013, was carried out. After propensity score matching, patients were divided into 2 groups: Group I 82 patients with sinus rhythm (SR) before surgery, Group II (control) 102 patients with AF before surgery. The average age of the included patients was 61 6.
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9

Gebrael, Georges, Yeonjung Jo, Chadi Hage Chehade, et al. "Treatment (Rx) patterns and attrition rates in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)." Journal of Clinical Oncology 43, no. 5_suppl (2025): 75. https://doi.org/10.1200/jco.2025.43.5_suppl.75.

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75 Background: The Rx landscape of pts with mCRPC has recently evolved with the approval of lutetium-177-PSMA-617 (Lu-177) and poly(ADP) ribose polymerase inhibitors (PARPi) either as single agents or as combinations with an androgen receptor pathway inhibitor (ARPI) [PMID: 37442702]. However, real-world data on the uptake of these agents are lacking. Herein, we sought to assess the Rx patterns and attrition rates of pts with mCRPC in the era of newly approved therapies. Methods: The de-identified nationwide Flatiron Health Electronic-Health Record (EHR)-derived database was used to extract pt
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10

Pauleit, D., H. Palmedo, H. Bender, et al. "Therapy of hepatocellular carcinoma with 131I-lipiodol: patient dosimetry." Nuklearmedizin 46, no. 05 (2007): 192–97. http://dx.doi.org/10.1160/nukmed-0086.

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SummaryAim: Dosimetry in 131I-lipiodol therapy for hepatocellular carcinoma (HCC) in the hitherto largest existing patient cohort. Patients, methods: 38 courses of intra-arterial 131I-lipiodol therapy with a total activity up to 6.7 GBq were performed in 18 patients with HCC. Liver and tumour volume were measured by computed tomography (CT) and 131I activity by scintigraphy on day 3, 6, 14, 28 and 42 after injection. Lipiodol deposition in tumour nodules as shown by CT rendered definite attachment to scintigraphic data possible. The radiation dose in tumour nodules, liver and lungs was calcula
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11

Torres Valdiviezo, Lucero Itzel, Karla Lucero Rodríguez Flores, Vanessa Rosas Rosas Camargo, et al. "Clinical characteristics, treatment, and oncological outcomes in patients with ampullary cancer at a reference center in Mexico." Journal of Clinical Oncology 40, no. 4_suppl (2022): 617. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.617.

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617 Background: Ampullary cancer (AC) represents 0.2% of gastrointestinal cancers. Given the rarity of the disease, information regarding treatment strategies and outcomes derives from studies that include the different types of periampullary cancers, which constitute a heterogeneous group. Our aim was to describe the clinical characteristics, treatment modalities and outcomes in patients (pts) with true AC treated at our institution. Methods: A retrospective review of medical records of all consecutive pts with histological diagnosis of AC evaluated at our institution from Jan 2009-Dec 2019.
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12

Vakulchyk, V. G., and A. V. Khudovtsova. "CLINICAL SIGNIFICANCE OF POLYMORPHONUCLEAR NEUTROPHILS IN THE STRATIFICATION OF CHILDREN WITH ACUTE ABDOMINAL PAIN." Journal of the Grodno State Medical University 20, no. 6 (2022): 607–12. http://dx.doi.org/10.25298/2221-8785-2022-20-6-607-612.

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Background. Acute abdominal pain in children is defined as acute pain of non-traumatic genesis lasting up to 5-7 days, and presents a serious diagnostic and tactical problem. Many aspects of diagnosis and treatment remain controversial. Aim. To determine the clinical significance of polymorphonuclear neutrophil count in the stratification of children with acute abdominal pain. Material and Methods. A prospective randomized blind clinical trial was performed. The results of examination and treatment of 633 children admitted to Grodno Regional Children's Clinical Hospital with acute abdominal pa
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13

Santos Filho, Serafim Barbosa, and Sandhi Maria Barreto. "Atividade ocupacional e prevalência de dor osteomuscular em cirurgiões-dentistas de Belo Horizonte, Minas Gerais, Brasil: contribuição ao debate sobre os distúrbios osteomusculares relacionados ao trabalho." Cadernos de Saúde Pública 17, no. 1 (2001): 181–93. http://dx.doi.org/10.1590/s0102-311x2001000100019.

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Estudo de prevalência de dor osteomuscular e fatores associados ao sintoma em cirurgiões-dentistas (n = 358), utilizando-se de questionário auto-aplicável, com dados sócio-demográficos, ocupacionais, psicossociais, hábitos de vida, localização e características de dor. 92% dos dentistas selecionados participaram do estudo. A prevalência de dor no segmento superior foi de 58%: 22% de dor no braço, 21% na coluna, 20% no pescoço e 17% no ombro; 26% relataram dor diária e 40% dor moderada/forte. Na análise multivariada (regressão logística múltipla), os fatores associados à dor foram: Pescoço: ans
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14

Leckett, Blaine, and Ralph J. Germinario. "Inability of insulin and insulinlike growth factor-1 to stimulate sugar or amino acid transport and thymidine incorporation in cultured myeloma cells." Biochemistry and Cell Biology 69, no. 12 (1991): 859–63. http://dx.doi.org/10.1139/o91-127.

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NS-1 mouse plasmacytoma cells were examined for their insulin and insulinlike growth factor-1 (IGF-1) binding characteristics and ability to produce peptide-dependent cellular effects. At concentrations of labelled insulin (i.e., 1.7 × 10−10 M) or IGF-1 (i.e., 1.5 × 10−10 M), NS-1 cells specifically bind 0.2 ± 0.06 fmol insulin per 106 cells (n = 7), where little, if any, IGF-1 specific binding was observed (0.02 ± 0.01 fmol/106 cells) (n = 3). Additionally, the data indicate that the total number of insulin binding sites per cell was 3200 ± 390 (n = 3). Insulin was employed at various concent
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15

Ali, Maisa, Faraj Alhowady, Waqar Munir, et al. "800. Drug-Resistant TB: An Experience From Qatar." Open Forum Infectious Diseases 5, suppl_1 (2018): S287. http://dx.doi.org/10.1093/ofid/ofy210.807.

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Abstract Background Drug-resistant tuberculosis (DR-TB) is an important issue for public health. This study was conducted to evaluate the characteristics, treatment outcome, and risk factors associated with 223 DR-TB cases in the State of Qatar. Methods A descriptive records-based retrospective study was conducted on patients registered at Communicable Disease Centre (CDC), Qatar to all consecutive microbiologically confirmed tuberculosis cases for the period January 2010–March 2015. Demographic and clinical data extracted included: patient’s age, sex, and country of origin; disease site (pulm
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16

Fettke, Heidi, Louise Kostos, James Buteau, et al. "Abstract 5614: Genomic aberrations in circulating tumor DNA (ctDNA) and clinical outcomes from [177Lu]Lu-PSMA-617 in metastatic castration-resistant prostate cancer (mCRPC)." Cancer Research 83, no. 7_Supplement (2023): 5614. http://dx.doi.org/10.1158/1538-7445.am2023-5614.

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Abstract [177Lu]Lu-PSMA-617 (LuPSMA) radionuclide therapy improves overall survival in mCRPC, and was recently approved by the FDA. Nevertheless, owing to the heterogeneous nature of mCRPC, responses to LuPSMA therapy can be variable, and resistance is inevitable. As a result, biomarkers linked to clinical outcome with LuPSMA are urgently required. Using plasma ctDNA, we present the first comprehensive genomic analysis of a prospective cohort of mCRPC patients treated with LuPSMA. Targeted sequencing of 78 genes was performed on baseline plasma and matched buffy coat samples from patients who
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17

Andriani, Alessandro, Roberto Latagliata, Michele Cedrone, et al. "Are ET and PV Patients Two Similar Populations As Concern Thrombotic Risk Factors?" Blood 126, no. 23 (2015): 2811. http://dx.doi.org/10.1182/blood.v126.23.2811.2811.

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Abstract Thrombotic events are major complications in patients (pts) affected by Essential Thrombocytemia (ET) and Polycytemia Vera (PV). To compare thrombotic risk in these 2 groups, we evaluated retrospectively our database of 1249 ET and 623 PV pts diagnosed and followed in 11 hematological centers in the Latium region between 1/1980 and 12/2010: the diagnosis was done according to PVSG, WHO 2001 and 2008criteria based on the time of first observation. Baseline features of ET pts: 797F/452M,median age 62.9 yrs (range 19-96),median WBC count 8.8 x 109/L (range 1.2-57.7), median PLT count 812
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18

Chu, Chang An, Pietro Galassetti, Kayano Igawa, et al. "Interaction of free fatty acids and epinephrine in regulating hepatic glucose production in conscious dogs." American Journal of Physiology-Endocrinology and Metabolism 284, no. 2 (2003): E291—E301. http://dx.doi.org/10.1152/ajpendo.00565.2001.

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To determine the effects of an increase in lipolysis on the glycogenolytic effect of epinephrine (EPI), the catecholamine was infused portally into 18-h-fasted conscious dogs maintained on a pancreatic clamp in the presence [portal (Po)-EPI+FFA, n = 6] and absence (Po-EPI+SAL, n = 6) of peripheral Intralipid infusion. Control groups with high glucose (70% increase) and free fatty acid (FFA; 200% increase; HG+FFA, n = 6) and high glucose alone (HG+SAL, n = 6) were also included. Hepatic sinusoidal EPI levels were elevated (Δ568 ± 77 and Δ527 ± 37 pg/ml, respectively) in Po-EPI+SAL and EPI+FFA b
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19

Sood, Ashwani, Swayamjeet Satapathy, Chandan Krushna Das, Piyush Aggarwal, and B. R. Mittal. "177 Lu-PSMA-617 consolidation therapy post docetaxel in patients with de-novo high-volume metastatic hormone-sensitive prostate cancer: A randomized, phase 2 trial." Journal of Clinical Oncology 43, no. 16_suppl (2025): 5095. https://doi.org/10.1200/jco.2025.43.16_suppl.5095.

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5095 Background: De-novo high-volume metastatic hormone-sensitive prostate cancer (mHSPC) presents a therapeutic challenge with a dismal five-year survival rate. Till recently, androgen deprivation therapy (ADT) with docetaxel had been the standard-of-care for such patients. Nevertheless, a substantial proportion of patients continue to harbour residual disease after completion of docetaxel. 177 Lu-PSMA-617 has shown positive survival outcomes in the metastatic castrate-resistant setting. Here, we intended to evaluate the role of upfront 177 Lu-PSMA-617 as consolidation therapy for residual di
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20

Chiu, Jen-Hwey, Chien-Hue Ju, Li-Hwa Wu, et al. "Cordyceps sinensisIncreases the Expression of Major Histocompatibility Complex Class II Antigens on Human Hepatoma Cell Line HA22T/VGH Cells." American Journal of Chinese Medicine 26, no. 02 (1998): 159–70. http://dx.doi.org/10.1142/s0192415x9800021x.

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Previous studies suggest that down-regulation of the major histocompatibility complex (MHC) antigens on the cell surface of certain tumors results in an escape of immune surveillance. Cordyceps sinensis is well known for its modulatory effect on host immune system. To investigate the modulatory effect of Cordyceps sinensis on MHC class II antigen expression on hepatoma cells, immunostaining with monoclonal antibody (MAb) L243, against the HLA DR region of MHC class II antigens on human hepatoma cell line HA22T/VGH was analyzed by using flow cytofluorimetry. The degree of fluorescence intensity
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21

Anuforo, Henry Uzoma, Toochukwu Ekwutosi Ogbulie, Angela Chika Udebuani, and Ethelbert Uchechukwu Ezeji. "Synthesis of Zinc Oxide Nanoparticles using Extract of Cynodon dactylon and Assessment of their Biological Activity against Staphylococcus aureus and Escherichia coli." UMYU Journal of Microbiology Research (UJMR) 8, no. 2 (2023): 74–85. http://dx.doi.org/10.47430/ujmr.2382.009.

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Nanotechnology is a groundbreaking technology that that has been widely applied in creating materials which are useful in various fields. It's important to maintain eco-friendly approaches for synthesis of nanoparticles by diversifying the substrate sources. In this study, the researchers used aqueous extract of Cynodon dactylon to synthesize zinc oxide nanoparticles (ZnONPs). Quantitative phytochemical analysis of the extract showed high concentrations of alkaloids, flavonoids, carbohydrates, proteins, amino acids, and phenolic compounds. In contrast, moderate concentrations of tannins, oils,
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22

Rai, Bharat, Ajaya K. Khadka, and Gyan M. Adhikari. "Factors Affecting Purchasing Behavior in Buying of Passenger Cars." Molung Educational Frontier 14 (July 22, 2024): 46–72. http://dx.doi.org/10.3126/mef.v14i01.67893.

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This study is about the consumer behavior in buying of passenger cars in Nepal. It aimed to identify the factors affecting the consumer behavior in car purchase. It used primary data, which came from a structured questionnaire on the six-point Likert scale that was sent to Nepalese car owners. Kathmandu was chosen as the sample site for our convenience to reach. Primary data was collected through the structured questionnaire. 411 car users were the sample size. SPSS software was used to prepare and look at the data. Through the path analysis, the effect of attributes, price, appearance, self-c
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23

Altaher, Al-Hussein, Maha Hamoudi, Ghassan Abdul-Majeed, and Faleh Almahdawi. "Enhancing Oil Production Rate by Well Type Conversion in an Iraqi Field." Iraqi Geological Journal 57, no. 2A (2024): 249–66. http://dx.doi.org/10.46717/igj.57.2a.18ms-2024-7-28.

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Horizontal wells have been drilled worldwide for the past decades, mainly to increase well’s deliverability. Many vertical wells have been converted to horizontal wells. Only some of them were successful in increasing the oil production rate as expected. In this study, a vertical well (V1) in Kirkuk field was studied and converted to a designed horizontal well (H1) to increase the productivity. PROSPER software was used to model both wells. H1 was designed with well horizontal lengths of 152, 305, 457, and 610 m, and permeability ratios of 0.1, 0.2, 0.4, 0.7 and 1.0. A developed correlation fo
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24

Renuka, Jain, Chitale Gauri, Rathore Kiran, and C. Jain Salish. "Diterpenoid quinones and other constituents from the roots of Clerodendron tomentosum R. Br." Journal of Indian Chemical Society Vol. 87, May 2010 (2010): 633–34. https://doi.org/10.5281/zenodo.5788437.

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Department of Chemistry, Department of Botany, University of Rajasthan, Jaipur-302 055, Rajasthan, India <em>E-mail :</em> profrjain@reditimail.com <em>Manuscript received 3 April 2009, revised 26 October 2009, accepted 9 November 2009</em> Chemical investigation of combined pet. ether and benzene fractions from the etbanolic extract of <em>Clerodendron tomentosum</em> R. Br. afforded three diterpenoid quinones, viz. 12-acetylroyleanone, royleanone and 6,7-dehydroroyleanone along with <em>n</em>-hexacosane, elcosanoic acid, (24S)-ethylcholesta-5,22.25-triene-3&beta;-ol, &alpha;-amyrln and olea
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25

Mantha, Simon, Debra Goldman, Sean M. Devlin, et al. "Determinants of Fatal Bleeding during Induction Therapy for Acute Promyelocytic Leukemia in the ATRA Era." Blood 124, no. 21 (2014): 948. http://dx.doi.org/10.1182/blood.v124.21.948.948.

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Abstract Background Acute promyelocytic leukemia (APL) is commonly complicated by complex coagulopathy. The early use of all-trans retinoic acid (ATRA) appears to have reduced induction mortality; however, with modern regimens the risk of early hemorrhagic death remains at about 5-10% in clinical trials and up to 30% in population-based studies. Previously identified as markers of bleeding risk in this setting are: white blood cell count (WBC), peripheral blood blast count, platelet count, fibrinogen, prothrombin time (PT), activated partial thromboplastin time (aPTT) and creatinine. Nonethele
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26

Giordano, M., P. Castellino, E. L. McConnell, and R. A. DeFronzo. "Effect of amino acid infusion on renal hemodynamics in humans: a dose-response study." American Journal of Physiology-Renal Physiology 267, no. 5 (1994): F703—F708. http://dx.doi.org/10.1152/ajprenal.1994.267.5.f703.

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We evaluated the dose-response relationship between the plasma amino acid (AA) concentration and renal hemodynamics in eight normal subjects. After an overnight fast, a balanced 10% AA solution was infused for 180 min at five separate infusion rates: 0.5 (group I), 1.0 (group II), 2.0 (group III), 4.0 (group IV), and 6.0 (group V) ml.kg-1.min-1 on separate days. Basal plasma AA concentration was 1.87 +/- 0.1 mmol/l and increased to 2.26 +/- 0.1 (group I), 2.66 +/- 0.2 (group II), 3.79 +/- 0.5 (group III), 5.81 +/- 0.4 (group IV), and 7.41 +/- 0.4 mmol/l (group V). Basal glomerular filtration r
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27

Zhang, Zengfeng, Zeqiang Zhan, and Chunlei Shi. "International Spread of Tet(X4)-Producing Escherichia coli Isolates." Foods 11, no. 14 (2022): 2010. http://dx.doi.org/10.3390/foods11142010.

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Tigecycline resistance in bacteria has become a significant threat to food safety and public health, where the development of which is attributed to plasmid-mediated tet(X4) genes. In this study, the genomes of 613 tet(X4)-producing Escherichia coli (E. coli) isolates, available from public databases, are evaluated to determine their international prevalence and molecular characterization. These E. coli isolates have been disseminated in 12 countries across Asia and Europe. It was found that pigs and their products (n = 162) were the most common vehicle, followed by humans (n = 122), chickens
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Zhu, Longkun, Vince Castranova, and Pingnian He. "fMLP-stimulated neutrophils increase endothelial [Ca2+]i and microvessel permeability in the absence of adhesion: role of reactive oxygen species." American Journal of Physiology-Heart and Circulatory Physiology 288, no. 3 (2005): H1331—H1338. http://dx.doi.org/10.1152/ajpheart.00802.2004.

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Our previous study demonstrated that firm attachment of leukocytes to microvessel walls does not necessarily increase microvessel permeability ( Am J Physiol Heart Circ Physiol 283: H2420–H2430, 2002). To further understand the mechanisms of the permeability increase associated with leukocyte accumulation during acute inflammation, we investigated the direct relation of reactive oxygen species (ROS) release during neutrophil respiratory burst to changes in microvessel permeability and endothelial intracellular Ca2+ concentration ([Ca2+]i) in intact microvessels. ROS release from activated neut
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29

Benaglia, P., C. H. Ishwara-Chandra, H. Intema, M. E. Colazo, and M. Gaikwad. "Cygnus survey with the Giant Metrewave Radio Telescope at 325 and 610 MHz: the catalog." Astronomy & Astrophysics 642 (October 2020): A136. http://dx.doi.org/10.1051/0004-6361/202037916.

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Context. Observations at the radio continuum band below the gigahertz band are key when the nature and properties of nonthermal sources are investigated because their radio radiation is strongest at these frequencies. The low radio frequency range is therefore the best to spot possible counterparts to very high-energy (VHE) sources: relativistic particles of the same population are likely to be involved in radio and high-energy radiation processes. Some of these counterparts to VHE sources can be stellar sources. Aims. The Cygnus region in the northern sky is one of the richest in this type of
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30

Josef Villafuerte, Conrad, Fred Gentili, David Shultz, et al. "RADT-19. EFFECTS OF RADIATION DOSE-RATE AND TUMOR CHARACTERISTICS ON LOCAL CONTROL AND TOXICITY AFTER RADIOSURGERY FOR ACOUSTIC NEUROMAS." Neuro-Oncology 22, Supplement_2 (2020): ii185. http://dx.doi.org/10.1093/neuonc/noaa215.772.

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Abstract INTRODUCTION The effect of stereotactic radiosurgery (SRS) dose-rate on tumor control for acoustic neuroma (AN, or vestibular schwannoma) is unclear. METHODS This was a retrospective study of all patients treated for AN with frame-based cobalt-60 SRS at the Toronto Western Hospital between 2005-2019. Dose rates on the day of SRS were calculated from the calibration dose-rate while accounting for the cobalt-60 half-life of 5.2713 years. Local failure was defined as continued tumor growth &amp;gt;36 months post-SRS, tumor resection for LF, or use of any repeat SRS for LF. Cumulative inc
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Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics
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Bouzabata, Amel, Faffani Boussaha, Joseph Casanova, and Félix Tomi. "Composition and Chemical Variability of Leaf Oil of Myrtus Communis from North-Eastern Algeria." Natural Product Communications 5, no. 10 (2010): 1934578X1000501. http://dx.doi.org/10.1177/1934578x1000501029.

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The chemical composition of 27 oil samples of Myrtus communis isolated from leaves collected in three locations in north–eastern Algeria was investigated by GC(RI) and 13C NMR spectroscopy. Yields ranged between 0.2-1.2% (w/w). The chemical composition of the oils was largely dominated by monoterpene hydrocarbons, with α-pinene (40.5-64.0%), 1,8-cineole (10.9-29.1%) and limonene (6.7-8.2%) being the major compounds. In all the samples, 3,3,5,5,8,8-hexamethyl-7-oxabicyclo[4.3.0]non-1(6)-ene-2,4-dione was identified (0.8-1.5%). The composition is similar to that reported for myrtle oils from Cor
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Benavides-Villanueva, F., C. Corrales-Selaya, I. Ferraz-Amaro, et al. "POS0623 SUBCLINICAL ATHEROSCLEROSIS IS NOT RELATED WITH ACID URIC IN RHEUMATOID ARTHRITIS. STUDY OF 1005 PATIENTS OF A SINGLE UNIVERSITY HOSPITAL." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 579.2–580. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4005.

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BackgroundRheumatoid Arthritis (RA) and Gout are associated with an increase of cardiovascular (CV) disease (1,2). Carotid plaques and increased carotid intima-media thickness (cIMT) are surrogate markers of CV mortality (3). The association of serum uric acid (SUA) levels as an independent factor of subclinical Atherosclerosis and mortality in RA remains not fully clarified (4,5).ObjectivesIn a wide cohort of patients with RA our aims were to assess the relationship of SUA with a) CV risk factors and b) presence of atherosclerosis.MethodsCross-sectional study including 1005 patients with RA f
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Mehta, P., T. Skaria, M. Pai, et al. "AB1460 CHARACTERISTICS AND EARLY OUTCOMES OF PALINDROMIC RHEUMATISM: AN INCEPTION COHORT FROM INDIA." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1958.1–1958. http://dx.doi.org/10.1136/annrheumdis-2023-eular.3719.

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BackgroundThe exact pathogenesis and risk factors of Palindromic Rheumatism (PR) remain uncertain, however, a subgroup of patients with PR share a close relationship with rheumatoid arthritis (RA) in terms of etiopathogenesis, clinical features, serology, and outcomes.ObjectivesWe aim to describe the characteristics of patients in an inception cohort of PR along with determinants of progression to RA.MethodsPatients with symptoms suggestive of PR were screened by a rheumatologist and after relevant exclusions, were classified into PR and included in an inception cohort at the Centre for Arthri
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Lv, Jun-lan, Rui-sheng Li, Shi-ying Jin та ін. "Changes of pharmacokinetics of 6,7-dimethoxycoumarin in a rat model of alpha-naphthylisothiocyanate-induced experimental hepatic injury after Yinchenhao Decoction (茵陈蒿汤) treatment". Chinese Journal of Integrative Medicine 18, № 11 (2012): 831–36. http://dx.doi.org/10.1007/s11655-012-1272-8.

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L. G., Hassan, Kabiru J. Umar, and Yuguda H. "Nutrition Evaluation of Faidherbia albida Seeds and Pulp as Source of Feeds for Livestock." African Journal of Food, Agriculture, Nutrition and Development 7, no. 16 (2007): 01–11. http://dx.doi.org/10.18697/ajfand.16.1835.

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The present study was conducted to find out the nutritional values of Faidherbia albida (Acacia albida) seeds and pulp to be used as components in livestock feeds. The samples were randomly collected from various trees during the period of January to February. The samples were separated, milled and analysed for proximate components and mineral elements using standard methods of the AOAC. Proximate analysis results showed that the concentrations of tested parameters in the seed and the pulp respectively on % dry matter were: dry matter (90.0 + 0.4; 93.3 + 0.2), ash (3.3 + 0.1; 6.7 + 0.1), crude
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Ivanchenko, A. V., V. A. Basharin, I. S. Drachev, A. B. Seleznev, and A. Yu Bushmanov. "To the Question About Pharmacological Protection During Irradiation In Non-infecting Doses: Maybe, Necessary? Communication 2. Review of Pathogenetic Aspects and Methods for Assessing the Efficiency of Anti-Radiation Agents in Experiment." MEDICAL RADIOLOGY AND RADIATION SAFETY 67, no. 4 (2022): 101–12. http://dx.doi.org/10.33266/1024-6177-2022-67-4-101-112.

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Purpose: Review and systematization of modern ideas about the mechanisms of the development of the effects of ionizing radiation in medium doses on a living organism in order to assess the need and possibility of using pharmaceutical agents suitable for modification purposes, about research methods in experiment; stimulation of discussion on the issue under consideration. Results: the current understanding of the genesis of radiation effects from irradiation at medium doses in the range of 0.2-1 Gy as a subject of modification with antiradiation agents is considered. Conclusions: The systemati
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Krishna, Varna, Vijay K. Shankar, Lakshmidevamma Madarakallu Muniyappa, and Mahagundappa M. Benal. "Prediction of Temperature During Machinability of Al2O3 Reinforced Al7075." Revue des composites et des matériaux avancés 30, no. 5-6 (2020): 241–46. http://dx.doi.org/10.18280/rcma.305-607.

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Metal matrix composite Al2O3 particle reinforced Al have become useful engineering materials due to their properties such as low cost, wear-resistant, heat-resistant and low weight. The present study focused on prediction of temperature produced during machining of Al2O3 reinforced with Al7075. In this investigation the percentage of Al2O3 (mesh size of 100-300)was varied 1%, 3%, 5%, 7% and 9% to the base material of Al7075. The temperature was measured using thermal gun at machining tip of the tool at which maximum temperature were measured by varying operational parameters such as depth of c
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Sluiter, Justin B., Helena Chum, Absai C. Gomes, et al. "Evaluation of Brazilian Sugarcane Bagasse Characterization: An Interlaboratory Comparison Study." Journal of AOAC INTERNATIONAL 99, no. 3 (2016): 579–85. http://dx.doi.org/10.5740/jaoacint.15-0063.

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Abstract This paper describes a study of the variability of measured composition for a single bulk sugarcane bagasse conducted across eight laboratories using similar analytical methods, with the purpose of determining the expected variation for compositional analysis performed by different laboratories. The results show good agreement of measured composition within a single laboratory, but greater variability when results are compared among laboratories. These interlaboratory variabilities do not seem to be associated with a specific method or technique or any single piece of instrumentation.
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Basijokas, Robertas, Kamilė Kaškelevičiūtė, and Donatas Austys. "Į ALKOHOLINIUS PANAŠIŲ GĖRIMŲ IR RŪKYMO VAIZDAVIMO PAPLITIMAS SOCIALINIUOSE TINKLUOSE: POPULIARIAUSIŲ LIETUVOS NUOMONĖS FORMUOTOJŲ ĮRAŠŲ „INSTAGRAM“ SOCIALINIAME TINKLE ANALIZĖ." Health Sciences 35, no. 3 (2025): 40–46. https://doi.org/10.35988/sm-hs.2025.099.

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Prie gyvensenos įpročių formavimo gali prisidėti pla­čiai naudojamų socialinių tinklų nuomonės formuotojai. Savo skelbiamu turiniu jie gali daryti tiek teigiamą, tiek neigiamą poveikį sekėjų gyvensenai. Atsižvelgiant į tai, kad Lietuvoje tokių tyrimų trūksta, šio tyrimo tikslas yra įvertinti alkoholinių gėrimų ir rūkymo rizikos veiksnių paplitimą populiariausių Lietuvos nuomonės formuotojų socialiniame tinkle „Instagram“ paskelbtuose įrašuose. Tyrimo medžiaga ir metodai. Šio tyrimo metu buvo ana­lizuojami visi (2 265) socialiniame tinkle „Instagram“ viešai prieinami populiariausių Lietuvos nuo
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Bai, Xue, Alexander Noor Shoushtari, Allison Betof Warner, et al. "Discrepancies in response and immune-related adverse events (irAE) of anti-PD-1 monotherapy between races and primary sites in patients (pts) with advanced nonacral cutaneous melanoma (NACM)." Journal of Clinical Oncology 39, no. 15_suppl (2021): 9530. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.9530.

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9530 Background: Ultraviolet (UV)-induced high tumor mutation burden (TMB) of NACM is associated with response to anti-PD-1 monotherapy (aPD-1). Anatomic location of the primary lesion (reflecting UV exposure) and race (reflecting eumelanin level) may serve as surrogates for TMB and be associated with varying response and irAE patterns. Methods: Pts with advanced NACM receiving aPD-1 between 2009-2019 were retrospectively analyzed from 5 institutions in the US, Australia and China. Best response, survival (PFS and OS), and organ/system-specific irAEs were compared by race (Caucasian [C] vs non
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Driscoll, Sarah, Gideon Meyerowitz-Katz, Golo Ahlenstiel, Tahlia Reynolds, Kate Reid, and Ramy H. Bishay. "Efficacy of Telephone Health Coaching Integration with Standard Multidisciplinary Care for Adults with Obesity Attending a Weight Management Service: A Pilot Study." Nutrients 13, no. 11 (2021): 4078. http://dx.doi.org/10.3390/nu13114078.

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Australia has one of the highest prevalences of obesity in the developed world with recognised gaps in patient access to obesity services. This non-randomised before and after study investigated the health benefits and patient acceptability of integrating the Get Healthy Service, a state-funded telephone-delivered coaching service in Australia, as an adjunct to multidisciplinary care for adults attending a public obesity service. Forty-one participants received multidisciplinary care alone while 39 participants were subsequently allocated to receive adjunctive treatment with the Get Healthy Se
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Barros, Roberto Augusto, Maria Jose Monteverde, Jean-Marc Dumonceau, et al. "Cold snare polypectomy without submucosal injection: safety and efficacy in 615 large serrated lesions." Endoscopy International Open 09, no. 09 (2021): E1421—E1426. http://dx.doi.org/10.1055/a-1517-4054.

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Abstract Background and study aim Cold resection is becoming the standard of care for the resection of nonpedunculated colon lesions up to 10 mm in diameter. Sessile serrated adenomas/polyps (SSA/Ps), including those ≥ 10 mm, present various characteristics that make them ideal candidates for cold snare polypectomy (CSP). Patients and methods A prospectively maintained database was searched retrospectively for consecutive patients with lesions ≥ 10 mm resected between March 2013 and March 2018. During that period, all SSA/P-appearing lesions were resected using CSP without submucosal injection
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Cabrera-Villalba, S., G. Avila, A. Amarilla, et al. "AB1364 VACCINATION AGAINST COVID-19 IN PARAGUAYAN PATIENTS WITH RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1912.1–1912. http://dx.doi.org/10.1136/annrheumdis-2023-eular.6094.

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BackgroundIn February 2021, the first doses of COVID-19 vaccines were received in Paraguay, and rheumatic patients were the preferred population to get these vaccines. Up to December 2022 the vaccination coverage in Paraguay was 59.4%, with at least one vaccine dose. 52.4% accessed the primary scheme (two doses), while 28.6% had at least one booster dose. Only 7.1% completed the COVID-19 immunization scheme.ObjectivesTo describe vaccination against COVID-19 in Paraguayan patients with Rheumatoid Arthritis (RA).MethodsDescriptive, cross sectional, observational study, in a Paraguayan cohort of
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Hao, Weihao, Jiahua Xu, Feiyu Zhao, Dong-Wook Sohn, and Xuepeng Shi. "Integration of Photovoltaic Shading Device and Vertical Farming on School Buildings to Improving Indoor Daylight, Thermal Comfort and Energy Performance in Three Different Cities in China." Buildings 14, no. 11 (2024): 3502. http://dx.doi.org/10.3390/buildings14113502.

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This study explores the integration of photovoltaic (PV) shading devices and vertical farming (VF) in school buildings to optimize indoor daylight, thermal comfort, and energy performance across three different climate regions in China: Beijing, Shanghai, and Shenzhen. With rapid urbanization and increasing energy consumption in educational buildings, this research investigates the impact of innovative facade design on both energy efficiency and occupant comfort. Through parametric simulations and multi-objective optimization, various PV and VF facade prototypes were evaluated to determine the
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Maděra, Petr, Radomír Řepka, Jan Šebesta, Tomáš Koutecký, and Martin Klimánek. "Vascular plant biodiversity of floodplain forest geobiocoenosis in Lower Morava river Basin (forest district Tvrdonice), Czech Republic." Journal of Landscape Ecology 6, no. 2 (2013): 34–64. http://dx.doi.org/10.2478/v10285-012-0067-3.

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ABSTRACT This paper presents an evaluation of full-area floristic mapping of floodplain forest in Tvrdonice forest district (Židlochovice Forest Enterprise) based on a single forest stand inventory. The study area encompasses 2,200 ha of forests, where 769 segments were inventoried, and 46,886 single records about presence of vascular plant species were catalogued. We found 612 species (incl. subspecies and hybrids), out of which 514 were herbs, 98 were woody plants, 113 were endangered species and 170 were adventive species. The average area of a segment is 2.86 ha. The mean number of species
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Stackhouse, S., E. Grafstein, and G. Innes. "LO82: Does triage assignment correlate with outcome for ed patients presenting with chest pain?" CJEM 21, S1 (2019): S37. http://dx.doi.org/10.1017/cem.2019.124.

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Introduction: CTAS triage acuity and CEDIS complaint categories are used to prioritize patients for rapid treatment and ED resource allocation. Our objective was to evaluate CTAS and CEDIS validity for risk stratification of ED patients with chest pain using data from two Canadian cities. Methods: This administrative database study included patients seen over a five-year period with a triage complaint of chest pain. Our composite primary outcome included 7-day mortality, cardiac arrest, acute coronary syndrome (ACS) diagnosis (STEMI, NSTEMI, unstable angina{UA}), admission to a critical care u
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Bialik, E. I., M. A. Makarov, V. A. Nesterenko, et al. "Evaluation of the efficacy of high molecular weight hyaluronic acid with chondroitin sulfate in post-traumatic knee osteoarthritis." Modern Rheumatology Journal 18, no. 4 (2024): 59–65. http://dx.doi.org/10.14412/1996-7012-2024-4-59-65.

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Objective: to evaluate the efficacy of a single or double administration of a preparation of high molecular weight hyaluronic acid (HLA) with chondroitin sulfate (CS) in post-traumatic knee osteoarthritis (OA). Material and methods. The study included 91 patients with stage III post-traumatic knee OA. All patients received intra-articular (i/a) injection of high molecular weight HLA with CS; 36 patients received the drug once (group 1) and 55 twice (group 2) with an average interval of 7±2 days. Before the start of treatment and 2 weeks, 1, 3, 6 and 12 months after i/a injection of HLA, pain i
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Ichinose, Masashi, and Takeshi Nishiyasu. "Muscle metaboreflex modulates the arterial baroreflex dynamic effects on peripheral vascular conductance in humans." American Journal of Physiology-Heart and Circulatory Physiology 288, no. 4 (2005): H1532—H1538. http://dx.doi.org/10.1152/ajpheart.00673.2004.

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We aimed to investigate the interaction between the arterial baroreflex and muscle metaboreflex [as reflected by alterations in the dynamic responses shown by leg blood flow (LBF: by the ultrasound Doppler method), leg vascular conductance (LVC), mean arterial blood pressure (MAP), and heart rate (HR)] in humans. In 12 healthy subjects (10 men and 2 women), who performed sustained 1-min handgrip exercise at 50% maximal voluntary contraction followed immediately by an imposed postexercise muscle ischemia (PEMI), 5-s periods of neck pressure (NP; 50 mmHg) or neck suction (NS; −60 mmHg) were used
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Arif, A. A., K. Donaldson, H. Qian, E. Lam, and N. C. Shahidi. "A123 MINIMALLY INVASIVE ENDOSCOPIC RESECTION TECHNIQUE PERFORMANCE FOR PERI-APPENDICEAL COLORECTAL NEOPLASIA: A SYSTEMATIC REVIEW AND META-ANALYSIS." Journal of the Canadian Association of Gastroenterology 5, Supplement_1 (2022): 144–45. http://dx.doi.org/10.1093/jcag/gwab049.122.

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Abstract Background Minimally invasive endoscopic resection techniques, including endoscopic mucosal resection (EMR), endoscopic submucosal dissection (ESD) and endoscopic full-thickness resection (EFTR) have revolutionized the management of peri-appendiceal colorectal neoplasia. However, questions remain about their comparative performance. Aims We sought to evaluate the performance of EMR, ESD and EFTR for peri-appendiceal colorectal neoplasia. Methods Two authors independently searched MEDLINE, EMBASE and Cochrane Libraries (Jan 2000 – Aug 2021) for citations evaluating the performance of e
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