Academic literature on the topic '6220f'

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Journal articles on the topic "6220f"

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Hobday, Timothy J., Rui Qin, Diane Lauren Reidy, et al. "Multicenter phase II trial of temsirolimus (TEM) and bevacizumab (BEV) in pancreatic neuroendocrine tumor (PNET)." Journal of Clinical Oncology 30, no. 4_suppl (2012): 260. http://dx.doi.org/10.1200/jco.2012.30.4_suppl.260.

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260 Background: Recent placebo-controlled phase III trials of the mTOR inhibitor everolimus and the VEGF/ PDGF receptor inhibitor sunitinib in PNET noted improved progression-free survival (PFS). However, objective response rates (RR) with these agents are <10%. Preclinical studies suggest enhanced anti-tumor effects with combined mTOR and VEGF targeted therapy. Methods: We conducted a phase II trial of the mTOR inhibitor TEM (25 mg IV q week) and the VEGF-A monoclonal antibody BEV (10 mg/kg IV q 2 weeks) in patients (pts) with well or moderately differentiated PNET and progressive disease
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Cohen, Deirdre Jill, Paul J. Christos, Joseph A. Sparano, et al. "A randomized phase II study of vismodegib (V), a hedgehog (HH) pathway inhibitor, combined with FOLFOX in patients (pts) with advanced gastric and gastroesophageal junction (GEJ) carcinoma: A New York Cancer Consortium led study." Journal of Clinical Oncology 31, no. 4_suppl (2013): 67. http://dx.doi.org/10.1200/jco.2013.31.4_suppl.67.

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67 Background: The HH pathway is overexpressed in gastroesophageal (GE) tumors. Pre-clinically, HH inhibitors have demonstrated a reduction in GE tumor growth, cell motility and invasiveness. V, an oral small-molecule antagonist of the Hh pathway, has previously been safely combined with FOLFOX chemotherapy. Methods: Pts with untreated, metastatic or locally advanced gastric or GEJ adenocarcinoma were randomized 1:1, stratified by institution and disease status (with or w/o distant mets) to FOLFOX (ox 85 mg/m2, LV 200 mg/m2, 5-FU bolus 400 mg/m2, 5-FU infusion 2400 mg/ m2 over 48 hrs) q14d plu
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Cohen, Deirdre Jill, Paul J. Christos, Hedy Lee Kindler, et al. "Vismodegib (V), a hedgehog (HH) pathway inhibitor, combined with FOLFOX for first-line therapy of patients (pts) with advanced gastric and gastroesophageal junction (GEJ) carcinoma: A New York Cancer Consortium led phase II randomized study." Journal of Clinical Oncology 31, no. 15_suppl (2013): 4011. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.4011.

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4011 Background: The HH pathway is overexpressed in gastroesophageal (GE) tumors. Pre-clinically, HH inhibitors have demonstrated a reduction in GE tumor growth, cell motility and invasiveness. V, an oral small-molecule antagonist of the Hh pathway, has previously been safely combined with FOLFOX chemotherapy. Methods: Pts with untreated metastatic or locally advanced gastric or GEJ adenocarcinoma were randomized 1:1, stratified by institution and disease status (with or w/o distant mets) to FOLFOX (ox 85 mg/m2, LV 200 mg/m2, 5-FU bolus 400 mg/m2, 5-FU infusion 2400 mg/ m2 over 48 hrs) q14d pl
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Morgan, Robert, Amit M. Oza, Rui Qin, et al. "A multicenter phase II study of bevacizumab (B) and temsirolimus (T) in women with recurrent epithelial ovarian cancer (OC): A study of the Mayo, Chicago, California, New York, Southeast, and Princess Margaret Phase II Consortia." Journal of Clinical Oncology 31, no. 15_suppl (2013): 5517. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.5517.

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5517 Background: Anti-angiogenic therapy is active in OC; the combination of VEGF and mTOR inhibitors is hypothesized to further improve activity. This report is the OC cohort of a multi-histology phase II study assessing the activity and toxicity of B/T. Methods: Patients (Pts) with recurrent epithelial OC who had received ≤ 2 chemotherapy regimens and no prior treatment with a VEGF or mTOR inhibitor were eligible. A two-stage design was used with second stage accrual if >6 pts had objective responses (OR) or >10 pts of the first 25 remained progression-free (PF) at six months (mo). Pre
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Ramalingam, S. S., M. Maitland, P. Frankel, et al. "Randomized, double-blind, placebo-controlled phase II study of carboplatin and paclitaxel with or without vorinostat, a histone deacetylase inhibitor (HDAC), for first-line therapy of advanced non-small cell lung cancer (NCI 7863)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 8004. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.8004.

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8004 Background: Vorinostat, a HDAC inhibitor, enhances paclitaxel and platinum-mediated anti-cancer activity in preclinical studies by enhanced tubulin acetylation and DNA fragmentation respectively. Promising activity with carboplatin (C), paclitaxel (P), and vorinostat in patients with advanced NSCLC in the phase I study (Ramalingam et al, Clin Cancer Res, 2007) prompted this placebo-controlled, randomized phase II study. Methods: Pts. with stage IIIB (wet) or IV NSCLC, performance status (PS) 0/1, no prior therapy and adequate bone marrow, renal and hepatic function were randomized (2:1) f
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Nedashkovskaya, Olga I., Seung Bum Kim, Dong Sung Shin, Irina A. Beleneva, and Valery V. Mikhailov. "Fulvivirga kasyanovii gen. nov., sp. nov., a novel member of the phylum Bacteroidetes isolated from seawater in a mussel farm." International Journal of Systematic and Evolutionary Microbiology 57, no. 5 (2007): 1046–49. http://dx.doi.org/10.1099/ijs.0.64641-0.

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A novel, strictly aerobic, heterotrophic, gliding, Gram-negative, oxidase-, catalase-, β-galactosidase- and alkaline phosphatase-positive marine bacterium, designated strain KMM 6220T, was isolated from seawater and studied by using a polyphasic taxonomic approach. The DNA G+C content of strain KMM 6220T was 59.9 mol%. The predominant fatty acids were iso-C15 : 1, iso-C15 : 0, iso-C15 : 0 3-OH, iso-C17 : 0 3-OH and C16 : 1 ω7/iso-C15 : 0 2-OH. Phylogenetic analysis based on 16S rRNA gene sequencing revealed that strain KMM 6220T formed a cluster with the misclassified strains [Flexibacter] agg
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PODHORN??, J., and KR??IAKM. "FANANSERIN (RR 62203), A POSSIBLE NOVEL ATYPICAL ANTIPSYCHOTIC?" Behavioural Pharmacology 7, Supplement 1 (1996): 89. http://dx.doi.org/10.1097/00008877-199605001-00202.

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Doble, A., O. Ferris, E. Heuillet, J. Ménager, and J. C. Blanchard. "3H-RP 62203: IN VITRO 5-HT2 BINDING STUDIES." Clinical Neuropharmacology 15 (1992): 581B. http://dx.doi.org/10.1097/00002826-199202001-01132.

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Malgouris, Christiane, Fabienne Flamand, and Adam Doble. "Autoradiographic studies of RP 62203, a potent 5-HT2 receptor antagonist. Pharmacological characterization of [3H]RP 62203 binding in the rat brain." European Journal of Pharmacology 233, no. 1 (1993): 37–45. http://dx.doi.org/10.1016/0014-2999(93)90346-j.

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Pinheiro, Gilson de Assis, Sérgio Henrique de Souza Alves, Pedro Paulo Murce, and Antonio Pedro de Mello Cruz. "Envolvimento dos receptores 5-HT2 da amígdala nos níveis de ansiedade induzidos pela exposição de ratos ao labirinto em cruz elevado." Psicologia: Teoria e Pesquisa 18, no. 3 (2002): 329–35. http://dx.doi.org/10.1590/s0102-37722002000300013.

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O efeito de microinjeções intra-amigdalóides do antagonista 5-HT2A/2C de receptores serotoninérgicos RP 62203 (1,0; 2,5; 5,0 mg) foi investigado em medidas tradicionais e etológicas (esquadrinhar, espreitar e explorações da extremidade) de ansiedade de ratos no labirinto em cruz elevado. A dose de 5,0 mg aumentou as porcentagens de entrada e de tempo nos braços abertos, sem alterar no número de entradas nos braços fechados. As categorias esquadrinhar, espreitar e explorações da extremidade também foram alteradas pela droga. As doses de 2,5 e 5,0 mg aumentaram o tempo gasto em esquadrinhar e di
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Dissertations / Theses on the topic "6220f"

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Pickard, Stephen. "The purpose of stating the faith : an historical and systematic inquiry into the tradition of fundamental articles with special reference to Anglicanism." Thesis, Durham University, 1990. http://etheses.dur.ac.uk/6220/.

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Stating the faith in the form of fundamental articles has, historically, provided an important strategy by which the identity and continuity of the Church has been expressed. The issue underlying this ecclesiological context of fundamental articles concerns the truth of the one-in-Christ bond in Christianity. However discussion of fundamental articles of the faith has, from the Post-Reformation period, tended to occur as somewhat disconnected from wider concerns to do with the belief, discipleship and mission of the Church. One result is that important issues and motives implicit in the attemp
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Lawrence, Peter James. "Mesh generation by domain bisection." Thesis, University of Greenwich, 1994. http://gala.gre.ac.uk/6220/.

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The research reported in this dissertation was undertaken to investigate efficient computational methods of automatically generating three dimensional unstructured tetrahedral meshes. The work on two dimensional triangular unstructured grid generation by Lewis and Robinson [LeR76] is first examined, in which a recursive bisection technique of computational order nlog(n) was implemented. This technique is then extended to incorporate new methods of geometry input and the automatic handling of multiconnected regions. The method of two dimensional recursive mesh bisection is then further modified
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Pesare, Daniele. "Musitique: Informatica ed evoluzione del linguaggio musicale." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amslaurea.unibo.it/6220/.

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Andreani, Lucia <1978&gt. "Development of an X-ray spectrometric system and feasibility tests of Silicon Drift Detector for medical and space applications." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2014. http://amsdottorato.unibo.it/6220/.

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The thesis work concerns X-ray spectrometry for both medical and space applications and is divided into two sections. The first section addresses an X-ray spectrometric system designed to study radiological beams and is devoted to the optimization of diagnostic procedures in medicine. A parametric semi-empirical model capable of efficiently reconstructing diagnostic X-ray spectra in 'middle power' computers was developed and tested. In addition, different silicon diode detectors were tested as real-time detectors in order to provide a real-time evaluation of the spectrum during diagnostic p
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Dang, Mau-Chien. "Comportement rhéologique, percolation et endommagement de matériaux à joints de grains visqueux, solides ou liquides." Grenoble INPG, 1994. http://www.theses.fr/1994INPG0083.

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Nous avons entrepris une etude systematique sur le comportement rheologique, la percolation et l'endommagement de materiaux contenant la phase intergranulaire eutectique. Cette etude a ete realisee a des temperatures englobant la temperature de fusion de la phase eutectique en vue d'obtenir deux types de joints: solide ou liquide. Tout au long de cette etude, nous nous sommes attaches a comparer le comportement du materiau a joints solides visqueux a celui du materiau a joints liquides. Un modele morphologique des grains avec des poches liquides a ete propose, ce qui permet de determiner la fr
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Hebe, Gasenakeletso Ennie. "Investigating Grade 3 learners’ changing mathematical proficiency in a maths club programme focused on number sense progression." Thesis, Rhodes University, 2018. http://hdl.handle.net/10962/62200.

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Recent international reports, for example TIMSS (2011 & 2015), point to serious challenges in South African learner performance in Mathematics and Science. Of greatest concern is that research findings (e.g. Graven, Venkat, Westaway and Tshesane 2013) suggest that many South African learners show signs of mathematical knowledge gaps in the lower grades. Hence, there is a need to address challenges of this nature very early in Foundation Phase. This study was undertaken with a view to contribute towards addressing mathematical challenges encountered by learners in Foundation Phase This empirica
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Novais, Ana Catarina Malheiro. "A prática na área da ginecologia e obstetrícia numa região da Amazónia Legal." Master's thesis, Instituto de Ciências Biomédicas Abel Salazar, 2010. http://hdl.handle.net/10216/62200.

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Souza, Sara Kanter Pinto de. ""A função social da propriedade industrial e o direito à proteção da saúde"." Master's thesis, Faculdade de Medicina da Universidade do Porto, 2011. http://hdl.handle.net/10216/62205.

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Pereira, Cátia Marisa Loureiro. "A simulação como metodologia de aquisição de competências na formação médica pré-graduada." Master's thesis, Instituto de Ciências Biomédicas Abel Salazar, 2010. http://hdl.handle.net/10216/62207.

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Bertão, Manuela Vidigal. "Estudo de prevalência do fenómeno de Raynaud na região do Grande Porto." Master's thesis, Instituto de Ciências Biomédicas Abel Salazar, 2010. http://hdl.handle.net/10216/62201.

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Books on the topic "6220f"

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Anuta, Michael J. Rotary clubs, Wisconsin and Michigan District 6220. M.J. Anuta, 1993.

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Kapferer, Wolfgang. The Mystery of Dark Matter. Springer Berlin Heidelberg, 2021. http://dx.doi.org/10.1007/978-3-662-62202-5.

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Arredondo, Patricia, Marie L. Miville, Christina M. Capodilupo, and Tatiana Vera. Women and the Challenge of STEM Professions. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-62201-5.

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Li, Wuyungerile, and Dalai Tang, eds. Mobile Wireless Middleware, Operating Systems and Applications. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-62205-3.

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Martin, Roy P., A. Michele Lease, and Helena R. Slobodskaya. Temperament and Children. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-62208-4.

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Cohen, Maurie J., ed. Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6.

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Lutz, James M. Import Propensities of Industrialized Countries. Palgrave Macmillan US, 2000. http://dx.doi.org/10.1007/978-1-349-62207-8.

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Karbo, Tony, and Kudrat Virk, eds. The Palgrave Handbook of Peacebuilding in Africa. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-62202-6.

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Rivera-Monroy, Victor H., Shing Yip Lee, Erik Kristensen, and Robert R. Twilley, eds. Mangrove Ecosystems: A Global Biogeographic Perspective. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62206-4.

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Lorick-Wilmot, Yndia S. Stories of Identity among Black, Middle Class, Second Generation Caribbeans. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-62208-8.

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Book chapters on the topic "6220f"

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Cohen, Maurie J. "Environmental Sociology, Social Theory, and Risk: an Introductory Discussion." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_1.

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Eder, Klaus. "Taming Risks through Dialogues: the Rationality and Functionality of Discursive Institutions in Risk Society." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_10.

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Lowenthal, David. "A Historical Perspective on Risk." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_11.

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Renn, Ortwin, Carlo C. Jaeger, Eugene A. Rosa, and Thomas Webler. "The Rational Actor Paradigm in Risk Theories: Analysis and Critique." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_2.

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Purcell, Kristen, Lee Clarke, and Linda Renzulli. "Menus of Choice: the Social Embeddedness of Decisions." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_3.

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Hogenboom, Joris, Arthur P. J. Mol, and Gert Spaargaren. "Dealing with Environmental Risks in Reflexive Modernity." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_4.

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Freudenburg, William R. "The ‘Risk Society’ Reconsidered: Recreancy, the Division of Labor, and Risks to the Social Fabric." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_5.

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Edelstein, Michael R. "‘Outsiders Just Don’t Understand’: Personalization of Risk and the Boundary Between Modernity and Postmodernity." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_6.

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Picou, J. Steven, and Duane A. Gill. "The Exxon Valdez Disaster as Localized Environmental Catastrophe: Dissimilarities to Risk Society Theory." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_7.

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Couch, Stephen R., Steve Kroll-Smith, and Jeffrey D. Kindler. "Discovering and Inventing Hazardous Environments: Sociological Knowledge and Publics at Risk." In Risk in the Modern Age. Palgrave Macmillan UK, 2000. http://dx.doi.org/10.1007/978-1-349-62201-6_8.

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Conference papers on the topic "6220f"

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Allal, Djamel. "EMPIR European project for validation of vector array SAR measurement systems." In 19th International Congress of Metrology (CIM2019), edited by Sandrine Gazal. EDP Sciences, 2019. http://dx.doi.org/10.1051/metrology/201902003.

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In the context of the new international standard IEC 62209-3 developed within IEC Technical Committee TC 106, EURAMET is running European research project Vector SAR with the aim to provide the validation methods, software tools and datasets required for traceable calibration and uncertainty analysis of vector probe array systems that automatically determine the 3D electromagnetic field and Specific Absorption Rate (SAR) mapping using amplitude and phase information through a 3D reconstruction algorithm.
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"Concrete Pumping: A New World Record." In SP-173: Fifth CANMET/ACI International Conference on Superplasticizers and Other Chemical Admixtures in Concrete. American Concrete Institute, 1997. http://dx.doi.org/10.14359/6220.

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Yamaguchi, Hitomi, Takeo Shinmura, and Megumi Sekine. "Factors Affecting the Finishing Characteristics of an Internal Magnetic Abrasive Finishing Process for High Purity Fittings." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-62202.

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In the case of internal finishing of the bent section of a complex shaped tube, such as found in high purity fittings, by a magnetic abrasive finishing process, the magnetic field at the finishing area and, therefore, the finishing force are hardly uniform over the entire finishing area due to the geometry. This affects the abrasive behavior against the inner surface of the bent section, changing the finishing characteristics of SUS304 stainless steel fittings. In practice, non-uniformities in the surface finish remain at the bent section between the inside, outside, and lateral regions. This
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Yu, Hui, Biao Li, Yi Zhao, and Xin Zhang. "Fabrication of Three-Dimensional SU-8 Microstructures for MEMS Applications." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-62203.

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In this paper, a novel method to realize three-dimensional microstructures is presented. The presented technology is based on a direct write technique using a scanning laser system to pattern thick-film SU-8. This technique combines the best features of photolithography techniques in multi-layer processing with the versatility of existing 3D prototyping technologies. It enables laser pulsing spot-by-spot for both in-plane and in-depth processing. The results presented here represent the first step towards the realization of categories of MEMS devices with mechanical, optical, and/or biological
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Lee, Y. C. E., E. H. K. Fung, J. Q. Zou, and H. W. J. Lee. "A Computational Optimal Control Approach to the Design of a Flexible Rotating Beam With Active Constrained Layer Damping." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-62205.

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In this paper, a computational approach is adopted to solve the optimal control and optimal parameter selection problems of a rotating flexible beam fully covered with active constrained layer damping (ACLD) treatment. The beam rotates in a vertical plane under the gravitational effect with variable angular velocity and carries an end mass. Tangent coordinate system and the moving coordinate system are used in the system modeling. Due to the highly nonlinear and coupled characteristics of the system, a relative description method is used to represent the motion of the beam and the motion equat
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Siliety, Mahmood, Eduardo Divo, and Alain J. Kassab. "Singular Superposition/BEM Inverse Technique for Reconstruction of Multi-Dimensional Heat Flux Distributions With Application to Film-Cooling Slots." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-62208.

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A hybrid singularity superposition/boundary element-based inverse problem method for the reconstruction of multi-dimensional heat flux distributions is developed. Cauchy conditions are imposed at exposed surfaces that are readily reached for measurements while convective boundary conditions are unknown at surfaces that are not amenable to measurements such as the edges of cooling slots. The purpose of the inverse analysis is to determine the heat flux distribution along cooling slot surfaces. This is accomplished in an iterative process by distributing a set of singularities at the vicinity of
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Yap, Y. F., J. C. Chai, K. C. Toh, T. N. Wong, and Y. C. Lam. "Numerical Modeling of Unidirectional Stratified Flow Between Parallel Plates." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-62209.

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Unidirectional stratified flow of two fluids between two parallel plates is modeled using the Level-Set method. A localized mass correction term is used to ensure mass conservation at every axial cross section. The mass correction term is based on the mass flowrates. Results for various combinations of density, viscosity and mass flowrate ratios are presented. Available fully-developed exact solutions for unidirectional stratified flow are used to validate the numerical simulations. The evolutions of the interface in the developing region are also captured and compared well with “exact” soluti
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Wang, Yang, Yulian Kin, Krasimir Zahariev, and Brian Smith. "Analysis and Optimization of Rotor Housing Assembly." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-62200.

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The paper presents analysis and optimization of the sonic drill head rotor housing assembly. The project was initiated by Layne Christensen DTC and performed at Purdue University Calumet in cooperation with the company engineers. Full finite element (FE) models of the rotor housing assembly were developed. Real world working conditions were applied onto the FE models in Ansys Workbench. With different Material setups, multiple trials were simulated so that the performances of material changes can be observed. Results of the total deformations were collected and analyzed both graphically and nu
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Selling, Joshua B. B., James E. Holliday, and Thomas M. Damiani. "Explicit Finite Element Fatigue Crack Growth Analysis of An Instrumentation Ring Under Thermal Transient Loading." In ASME 2021 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/pvp2021-62207.

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Abstract ASME PVP conference papers from 2007 and 2008 (References [1] and [2]) discuss fatigue analyses related to 304 stainless steel instrumentation spacer rings (rings) that had cracked while installed in a thermal fatigue test loop. The rings contain circular radial penetrations extending through the ring that allow access for instrumentation probes to monitor the fluid temperature and pressure. Routine inspection of the test loop revealed actively growing cracks in each port that appeared to start near the inner diameter (ID) of the ring. In this work, three-dimensional finite element an
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Banyay, Gregory A., Matthew J. Palamara, and Stephen D. Smith. "Coupling of Neutron Noise and Dynamic Finite Element Analyses to Perform Remote Condition Monitoring for Reactor Vessel Internals." In ASME 2021 Pressure Vessels & Piping Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/pvp2021-62201.

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Abstract During a Spring 2019 refueling outage, Plant A, a pressurized water reactor (PWR), experienced difficulty removing the reactor vessel upper internals because of degraded thermal shield (TS) support block bolts (TSSBBs), TS flexures, and baffle-former bolts (BFBs). None of the degradation was expected based on prior industry operating experience. Dynamic finite element analyses (FEA) and neutron noise monitoring were performed to diagnose the degraded condition. The FEA simulated the indications from the 2019 outage to assess the effect that degradation would have on the dynamic respon
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