Relevant bibliographies by topics / 624.151 32

Journal articles
Book chapters
Conference papers
Reports

Academic literature on the topic '624.151 32'

Author: Grafiati

Published: 4 June 2021

Last updated: 8 June 2024

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic '624.151 32.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "624.151 32"

Kusumaningtyas, Rozhalia Uji, and Sri Suparti. "Stress and Anxiety Level of Nursing Students in Facing Practical Exam During Pandemic 19." Proceedings Series on Health & Medical Sciences 3 (December 28, 2022): 98–103. http://dx.doi.org/10.30595/pshms.v3i.627.

Full text

Abstract:

Background: Persons enrolled in nursing school are prepared to advance into nursing in the future. Before engaging in nursing clinical practice in hospitals, nursing students are required to be able to advance their competence in the lab. Students studying nursing experience stress and anxiety due to the switch from online to offline lab learning. Objective: To determine and identify nursing students’ stress and anxiety levels in facing practical exams. Method: This study is cross-sectional quantitative descriptive research. A total of 190 nursing students from the second semester at Universitas Muhammadiyah Purwokerto participated in the study as the sample on April 20, 2022. The DASS-21 questionnaire for sub-stress and anxiety was modified for the research instrument. A univariate data analysis with frequency distribution was used as the data analysis. Results: The findings revealed that 115 (60.5%) nursing students reported normal stress, 32 (16.8%) mild stress, 23 (12.1%) moderate stress, 18 (9.5%) severe stress, and 2 (1.1%) very heavy stress. There were 32 (16.8%) students who moderate anxiety, 26 (13.7%) severe anxiety, and 28 (14.7%) very severe anxiety. Conclusion: Most nursing students preparing for practical exams experienced normal stress and moderate anxiety levels.

APA, Harvard, Vancouver, ISO, and other styles

Raičević, Jelena G., Ivan N. Pavlović, and Tamara A. Galonja-Coghill. "Canine intestinal parasites as a potential source of soil contamination in the public areas of Kruševac, Serbia." Journal of Infection in Developing Countries 15, no. 01 (January 31, 2021): 147–54. http://dx.doi.org/10.3855/jidc.12694.

Full text

Abstract:

Introduction: Environmental contamination by infected canine faeces presents an indirect source of contamination in people. In this research the presence of parasitic elements in canine faeces found in the public areas of Kruševac was examined. Methodology: During May and October 2018, 282 samples were collected from different public areas (ten kindergartens, six public squares and four parks). The examination of faeces was performed by means of direct smear and flotation. For statistical testing of the difference between the frequencies of attributes χ2 test was applied. Results: Out of 282 samples, 221 (78.4%) were positive, of which 17/20 (85.0%) from kindergartens, 125/160 (78.1%) from parks and 79/102 (77.5%) from public squares. The presence of Ancylostomatidae spp. was discovered in 113 (40.1%) samples, Toxocara canis in 82 (29.1%), Dipylidium caninum in 76 (27.0%), Giardia intestinalis in 45 (16.0%), Taenia spp. in 44 (15.6%), Amoeba spp. in 32 (11.3%), Trichuris vulpis in 19 (6.7%), Toxascaris leonina in 18 (6.4%), Strongyloides stercoralis in 17 (6.0%), Isospora spp. in 7 (2.5%) and Cryptosporidium spp. in 3 (1.1%). In May there were 115/141 (81.6%) positive samples, whereas in October there were 106/141 (72.5%) positive ones. No positive sample with three or four parasites was found in October. Conclusions: This study shows that canine faeces from public areas in Kruševac can be the cause of a significant environmental contamination by eggs of canine intestinal parasites as well as of human infections.

APA, Harvard, Vancouver, ISO, and other styles

Voitl, Peter, Rosmarie Meyer, Astrid Woditschka, Christian Sebelefsky, Andreas Böck, and Verena Schneeberger. "Occurrence of patients compared in a pediatric practice and pediatric hospital outpatient clinic." Journal of Child Health Care 23, no. 4 (May 26, 2019): 512–21. http://dx.doi.org/10.1177/1367493519853431.

Full text

Abstract:

The frequency of consultations and the waiting times in pediatric hospital outpatient clinics are steadily increasing. The aim of this study was to compare the occurrence of patients in a large pediatric group practice and a hospital-based general pediatric outpatient clinic. Primary parameters were the most common reasons for consultation, the waiting times and the reasons for selecting a certain institution. Most frequent diagnoses in the pediatric practice were upper respiratory tract infections (22.7% ( n = 141/621)), otitis media (5.2% ( n = 32/621)), and viral pharyngitis (3.9% ( n = 24/621)). Most common reasons for consultation in the hospital outpatient clinic were upper respiratory tract infections (18.4% ( n = 121/658)) and bacterial pharyngitis (17.9% ( n = 118/658)). In the pediatric practice, bacterial pharyngitis was only diagnosed in 3.1% ( n = 19/621) of the cases. Only slight differences exist between the two institutions regarding the observed entities, which mainly comprise mild to moderate acute illnesses. It can be concluded from this that the majority of patients might as well be treated in the nonhospital setting. Facilitating the communication and coordination between practices and hospitals might allow a better utilization of capacities. Thereby, waiting times, unnecessary reexaminations, and costs in the health-care system could be reduced.

APA, Harvard, Vancouver, ISO, and other styles

Yee, A., L. Siriwardhana, G. Nixon, L. Walter, F. Wong, and R. Horne. "P141 Periodic breathing in preterm infants before and after hospital discharge." SLEEP Advances 3, Supplement_1 (October 1, 2022): A75. http://dx.doi.org/10.1093/sleepadvances/zpac029.209.

Full text

Abstract:

Abstract Introduction Preterm infants have immature respiratory control that can manifest as periodic breathing (PB). We aimed to investigate the relationship between time spent in PB before and after hospital discharge. Methods Preterm infants born between 28-32 weeks gestational age were studied during daytime sleep in the supine position for 2-4 hours at 32-36 weeks post menstrual age (PMA) (N=40), 36-40 weeks PMA (N=27), 3 months (N=20) and 6 months (N=26) corrected age (CA). The amount of PB was determined as percentage of total sleep time (TST) spent in PB (%TSTPB). Infants were grouped into below and above the median (8.5%TSTPB) at 32-36 weeks and compared to 36-40 weeks, 3 and 6 months with Mann-Whitney U tests. Results %TSTPB was not different between 32-36 weeks PMA (median 8.5%; IQR 1.5, 15.0) and at 36-40 weeks PMA (6.6% (0.9, 15.1), and then decreased at 3 (0.4%; 0.0, 2.0) and 6 months CA (0%; 0.0, 1.1). Infants who were above the median %TSTPB at 32-36 weeks PMA spent more time in PB at 36-40 weeks PMA [18.05% (7.7, 23.9) vs 2.1% (0.6, 6.4)] and 6 months CA [0.9% (0.0, 3.3) vs 0.0% (0.0, 0.0)]. Conclusions Percentage sleep time spent in PB did not decrease as preterm infants approached term CA, when they were ready to be discharged home. Preterm infants who had higher amounts of PB at 32-36 weeks PMA continued to have higher amounts of PB at term CA and their PB persisted up to 6 months CA.

APA, Harvard, Vancouver, ISO, and other styles

ΚΑΡΔΑΡΑΣ, Γεώργιος. "Βιβλιοκρισία: Neglected Barbarians, επιμ. εκδ. F. CURTA [Studies in the Early Middle Ages 32], Brepols Publishers n.v., Turnhout 2010. 629 σ., 24 έγχρωμες εικόνες, ISBN: 978-2-503-53125-0." BYZANTINA SYMMEIKTA 22 (April 26, 2013): 443. http://dx.doi.org/10.12681/byzsym.1114.

Full text

Abstract:

Βιβλιοκρισία: Neglected Barbarians, επιμ. εκδ. F. Curta [Studies in the Early Middle Ages 32], Brepols Publishers n.v., Turnhout 2010. 629 σ., 24 έγχρωμε&sigmaf; εικόνε&sigmaf;, ISBN: 978-2-503-53125-0Negle

APA, Harvard, Vancouver, ISO, and other styles

Di Gioia, Giuseppe, Lorenzo Buzzelli, Viviana Maestrini, Antonio Nenna, Sara Monosilio, Maria Rosaria Squeo, Erika Lemme, and Antonio Pelliccia. "Lipid Profile in Olympic Athletes: Proposal for a “Lipid Athlete Score” as a Clinical Tool to Identify High-Risk Athletes." Journal of Clinical Medicine 12, no. 23 (November 30, 2023): 7449. http://dx.doi.org/10.3390/jcm12237449.

Full text

Abstract:

Dyslipidemia is a major risk factor for atherosclerosis. Identification of dyslipidemia in athletes has raised interest in establishing preventive strategies and reducing cardiovascular (CV) events. Nowadays, targets or “scores” for athletes are undefined. The aim of our study was to create a “Lipid Athlete Score” based on lipid parameters and derive score indexes to identify high-risk athletes. We retrospectively enrolled 957 Olympic athletes practicing different sporting disciplines (power, skills, endurance, and mixed), analyzing their CV profiles and anthropometrics; 55.4% were male, the mean age was 27.1 ± 5 years, and the mean body mass index (BMI) was 23.1 ± 3.2 kg/m2. Three hundred and forty-three athletes (35.8%) were dyslipidemic (LDL ≥ 115 mg/dL or LDL/HDL ≥ 1.90). Multivariate analysis revealed the following: male p = 0.001, OR 1.88 [0.41–2.51], familiarity for dyslipidemia p = 0.001, OR 2.82 [1.72–4.59], BMI ≥ 30 kg/m2 p = 0.001, OR 2.53 [1.46–4.38], and fat mass p = 0.001, OR 2.29 [1.38–3.80] were significant. Endurance athletes presented the lowest CV risk. We proposed a lipid athlete score including major (LDL ≥ 115 mg/dL and LDL/HDL ≥ 1.90) and minor criteria (male, BMI > 30 kg/m2 or fat mass >22% for males and 32% for females, familiarity for dyslipidemia, and conventional CV risk factors). Twelve athletes (1.2%) were at high risk, 150 athletes (15.7%) at medium risk, 171 athletes (17.9%) at low risk, and 624 (65.2%) were at no risk. Dyslipidemia is very common in elite athletes. We have defined a specific lipid athlete score based on lipid parameters and derived score indexes for the stratification of risk. In accordance with this tool, a substantial proportion of athletes (16.9%) were at medium-to-high risk and need early preventive strategies to improve their lipid profiles and reduce the future development of atherosclerotic CV diseases.

APA, Harvard, Vancouver, ISO, and other styles

Dametto, Leonardo Luiz, Ezequiel Davi dos Santos, Luciana R. Santos, and Elci L. Dickel. "Bovine tuberculosis: diagnosis in dairy cattle through the association of analyzes." Pesquisa Veterinária Brasileira 40, no. 1 (January 2020): 12–16. http://dx.doi.org/10.1590/1678-5150-pvb-6294.

Full text

Abstract:

ABSTRACT: Tuberculosis is a chronic anthropozoonosis of worldwide occurrence, caused by the bacterium Mycobacterium tuberculosis and its variants. In Brazil, the National Program for the Control and Eradication of Brucellosis and Tuberculosis in cattle, is responsible for diagnosing and the correctly allocate positive animals, but there is still a lack of definitive diagnosis of the disease. This study described the use of five diagnostic tools that can be used, preferably together, for the confirmation of suspected cases. These tools included the clinical examination comparative cervical tuberculin test, macroscopic findings during the slaughtering and histopathology of the damaged tissues followed by histochemistry. We evaluated a total of 211 dairy cattle, where 15.1% (32/211) had classic clinical signs of bovine tuberculosis, 74 (35%) showed reactivity in the comparative cervical tuberculin test. Of the total number of animals, 141 (66.8%) were referred for sanitary slaughter due to legal and control issues in the outbreaks of the disease. In the follow-up of slaughtering and inspection of viscera and carcasses, 74 (52.5%) had macroscopic lesions compatible with bovine tuberculosis, while 67 (47.5%) showed no visible changes. During the inspection, fragments of lymph nodes and liver and lung parenchyma were collected from five cattle with macroscopic lesions and five with no lesions. The histopathological analysis showed numerous areas of caseous necrosis with or without central calcification and granulomatous inflammatory infiltrate. In the special staining of Ziehl-Neelsen, numerous acid-fast bacilli were evidenced in all cases.

APA, Harvard, Vancouver, ISO, and other styles

Schultz, N. A., J. Werner, H. Willenbrock, A. Roslind, T. Horn, M. Wøjdemann, and J. S. Johansen. "MicroRNA expression profiles associated with pancreatic cancer." Journal of Clinical Oncology 29, no. 4_suppl (February 1, 2011): 153. http://dx.doi.org/10.1200/jco.2011.29.4_suppl.153.

Full text

Abstract:

153 Background: The aim was: 1) to define the global microRNA (miRNA) expression pattern in pancreatic cancer (PC) and compare it with normal pancreas (NP) and chronic pancreatitis (CP); 2) to validate reported diagnostic miR profiles in PC; 3) to discover new diagnostic miRs in pancreas samples without micro-dissection of cancer cells. Methods: MiR expression patterns in FFPE tissue blocks from patients operated for pancreatic ductal adenocarcinoma (PDAC, n=170) and ampullary adenocarcinomas (A-AC, n=107) were determined using TaqMan Human miR microarrray (Applied Biosystem; 754 miRs were determined) and compared to profiles of CP (n=23) and NP (n=28). Raw Ct-values were normalized using quantile-normalisation. Results: 83miRs were differentially expressed in PDAC and NP (42 higher expression; 41 reduced expression in PDAC). 32 miRs were differentially expressed in PDAC and CP. The most differentially expressed miRs were miR-614, miR-492, miR-622, miR-135b* and miR-196. The miR signatures of PDAC and A-AC were highly correlated (0.99; only 5 miRs were significantly differentially expressed). An earlier reported diagnostic miR profile for PDAC was validated (mirR196b - miR217), and 3 other significant profiles were identified (Table). A more complex Lasso classifier using 19 miRs could separate PDAC from NP and CP (accuracy = 98%). Conclusions: We identified systematic differences in patterns of miR expressions between tumor tissue including both cancer cells and surrounding desmoplasia obtained from patients with PDAC and A-AC compared to tissue from patients with CP and NP. We validated the diagnostic miR expression profile (miR-196b, miR-217) described by Szafranska et al. (Clin Chem 2008;54:1716-24). Furthermore, we identified 5 miRs which were better to discriminate PDAC and A-AC from CP and NP. Prospective studies are needed to evaluate if this panel of miRs is useful for early diagnosis of patients with PDAC. [Table: see text] No significant financial relationships to disclose.

APA, Harvard, Vancouver, ISO, and other styles

Matveev, V. B., M. I. Volkova, N. L. Vashakmadze, and I. S. Stilidi. "Technique and short-term outcomes of surgical treatment in patients with renal cell carcinoma and tumor venous thrombosis: experience of the Urology Clinic, N.N. Blokhin National Medical Research Center of Oncology." Cancer Urology 17, no. 2 (July 25, 2021): 17–32. http://dx.doi.org/10.17650/1726-9776-2021-17-2-17-32.

Full text

Abstract:

Objective: to describe the technique of nephrectomy and thrombectomy used in patients with renal cell carcinoma (RCC) and tumor venous thrombosis of various levels, and to identify risk factors of in-hospital death among operated patients.Materials and methods. This study included 768 patients with RCC and tumor venous thrombosis who have undergone surgical treatment. Median age was 58 years (range: 16-82 years); the male to female ratio was 2.3:1. The symptoms of venous tumor thrombosis were identified in 199 patients (25.9 %). In the majority of patients (n = 509; 66.3 %), the tumor thrombus originated from the right renal vein. The cranial border of the tumor thrombus was located in the perirenal inferior vena cava (IVC) in 219 patients (28.5 %), subhepatic IVC in 201 patients (26.2 %), intrahepatic IVC in 171 patients (22.3 %), and above the diaphragm in 177 patients (23.0 %). We used an individual approach to choose an optimal method of vascular control and to identify indications for circulatory support. Two-thirds of patients (n = 512; 66.7 %) underwent temporary block of the second renal vein; 268 patients (34.9 %) - temporary block of the hepatoduodenal ligament and right heart; 11 patients (3.2 %) were operated on with cardiopulmonary bypass.Results. The median surgery time was 190 ± 63.6 min; median blood loss was 3,000 ± 71.6 mL (≥50 % of circulating blood in 35.1 % of patients). Intraoperative complications were registered in 23 patients (3.0 %); eight patients (1.0 %) died during surgery with 4 of them died due to pulmonary embolism (0.5 %), 3 died due to hemorrhagic shock (0.4 %), and 1 died due to myocardial infarction (0.1 %). One hundred and ninety individuals (25.0 %) developed postoperative complications with Clavien-Dindo grade III-V complications observed in 115 cases (15.1 %). Forty-one patients (5.3 %) died in the early postoperative period. The causes of death included multiple organ dysfunction (n = 21; 2.8 %), pulmonary embolism (n = 7; 0.9 %), sepsis (n = 6; 0.8 %), stroke (n = 4; 0.5 %), myocardial infarction (n = 2; 0.2 %), and RCC progression (n = 1; 0.1 %). We have identified several independent risk factors for in-hospital mortality, including ascites (hazard ratio (HR) 8.3; 95 % confidence interval (CI) 3.2-21.4; p < 0.0001), preoperative pulmonary embolism (HR 3.5; 95 % CI 1.3-9.4; p = 0.013), supradiaphragmatic thrombi (HR 1.5; 95 % CI 1.1-2.0; p = 0.003). The in-hospital mortality rate was 3.5 % (20/575) among patients with no risk factors, 9.8 % (16/163) among those with 1 risk factor, 40.0 % (10/25) among those with 2 risk factors, and 60.0 % (3/5) among those with 3 risk factors (area under the curve (AUC) 0.705; p <0.0001 for all).Conclusion. The incidence of severe complications and postoperative mortality rate in RCC patients with tumor venous thrombosis who have undergone nephrectomy and thrombectomy were 15.1 and 6.4 %, respectively. Risk factors for perioperative mortality included ascites, preoperative pulmonary embolism, and supradiaphragmatic thrombosis.

APA, Harvard, Vancouver, ISO, and other styles

Fruth, Briant, Tom R. Fitch, Robert P. Shannon, Ryan Uitti, Elise Carey, Cory Ingram, Angelina D. Tan, et al. "A dynamic managed care platform for palliative care." Journal of Clinical Oncology 35, no. 31_suppl (November 1, 2017): 32. http://dx.doi.org/10.1200/jco.2017.35.31_suppl.32.

Full text

Abstract:

32 Background: The link between patient concerns and clinical systems delivery is often suboptimal. We developed a case management system for palliative care which transforms the patient’s greatest concerns into actionable clinical pathways. Methods: The system collects patients’ single greatest and second greatest concern plus Quality of Life (QOL) data (pain, fatigue and overall QOL single-items scored 0-10 with 10 representing worst pain/fatigue, or best QOL) and produces a report to guide the physician and patient. The system presents ten “buttons” in a xylophone-like grid: Personal Relationships, Monitoring Health, Emotional Health, Money, Health Behaviors, Medication Troubles, Care Access, Work Worries, Physical Health and Care Planning. We performed a quality improvement study at Mayo Clinic sites. Results: 409 patients participated in at least one survey from 11/04/2015 to 9/22/2016 (620 total surveys). The most common Main Concern was Physical Health 265/620 (43%) followed by Monitoring Health (17%), Medication (8%), and Emotional Health, Money, and Health Behaviors (7% each), Personal Relationships (6%). Future Care Planning, Work, and Care Access/Coordination were rarely chosen ( < 5%). The most common Second greatest concern was Health Behaviors 73/409 (18%) followed by Physical Health (17%). 93/122 (67%) patients changed their greatest concern from baseline to subsequent visits. The mean QOL, fatigue and pain at baseline were 4.8, 6.0 and 4.8 respectively, indicating substantial clinically significant deficits. Post baseline mean scores improved by a maximum of 0.8, 1.1, and 0.9 points respectively, representing clinically meaningful effects. On average it took 8 minutes for patients to use the system. Conclusions: The system was quick and easy to utilize. The personal impact concerns (physical/emotional health, medications) were most often cited as the greatest concern, while care issues were de-emphasized by patients. Patients and physicians praised the system for making visits more efficient and raising issues that otherwise might not have been addressed. This system has the potential to improve patient well-being and clinical outcomes, as well as to reduce burden on clinicians and optimize case management activities.

APA, Harvard, Vancouver, ISO, and other styles

More sources

Book chapters on the topic "624.151 32"

Guerrieri, Emilio, Mohammad Hayat, Hassan Ghahari, Vladimir A. Trjapitzin, Gennaro Viggiani, and Gary A. P. Gibson. "Family Encyrtidae Walker, 1837." In Chalcidoidea of Iran (Insecta: Hymenoptera), 93–152. Wallingford: CABI, 2021. http://dx.doi.org/10.1079/9781789248463.0005.

Full text

Abstract:

Abstract Species from the family Encyrtidae are all endoparasitoids and some are polyembryonic. Many species have been used successfully in various biological control programmes in different regions of the world. This chapter provides a checklist for the family Encyrtidae. It provides information on species diversity, host records, distribution records by province in Iran, as well as world distribution. Comparison of the encyrtid fauna of Iran with adjacent countries indicates that the faunas of Russia (492 species) and Turkmenistan (246 species) are more diverse than Iran (236 species), followed by Armenia (174 species), Turkey (165 species), Azerbaijan (159 species), Kazakhstan (148 species), Pakistan (62 species), Saudi Arabia (47 species), Afghanistan (32 species), Iraq (seven species), United Arab Emirates (three species), Oman (two species), Kuwait (one species) and Bahrain and Qatar (no species). Among the adjacent countries, Russia shares 129 known species with Iran, followed by Azerbaijan (105 species), Turkey (98 species), Armenia (91 species), Turkmenistan (67 species), Kazakhstan (64 species), Pakistan (27 species), Afghanistan (17 species), Saudi Arabia (16 species), Iraq (five species), United Arab Emirates (three species) and Oman (two species).

APA, Harvard, Vancouver, ISO, and other styles

Full text

Abstract:

APA, Harvard, Vancouver, ISO, and other styles

de Terwangne, Cécile. "Article 5 Principles relating to processing of personal data." In The EU General Data Protection Regulation (GDPR). Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198826491.003.0034.

Full text

Abstract:

Article 6(1) (Lawfulness of processing) (see too recitals 40–49); Article 6(4) (Exceptions to the requirement of compatible purposes for further processing and criteria to ascertain whether a purpose of further processing is compatible with the purpose for which the personal data are initially collected) (see too recital 50); Article 12 (Transparent information) (see too recitals 58–59); Articles 13–15 (Information and access to personal data) (see also recitals 60–64); Article 24 (Responsibility of the controller) (see too recitals 74–78) ; Article 32 (Security of processing) (see too recital 83); Article 89(1) (Safeguards and derogations relating to processing for archiving purposes in the public interest, scientific or historical research purposes or statistical purposes) (see too recitals 158–163).

APA, Harvard, Vancouver, ISO, and other styles

"Paddlefish Management, Propagation, and Conservation in the 21st Century." In Paddlefish Management, Propagation, and Conservation in the 21st Century, edited by JEFFREY W. QUINN, WILLIAM R. POSEY, FRANK J. LEONE, and ROBERT L. LIMBIRD. American Fisheries Society, 2009. http://dx.doi.org/10.47886/9781934874127.ch16.

Full text

Abstract:

Abstract.— Four special commercial fishing seasons (5–10 d) with mandatory check stations were used to closely monitor the harvest and exploitation of paddlefish Polyodon spathula in Ozark Lake and Pool 13 of the Arkansas River, Arkansas. The mean number of fishers (± SD) participating was 36 ± 25, and participation of statewide licensed fishers was high at 64% ± 18%. Average harvest (± SD) among seasons was 1,538 ± 652 fish and 866 ± 319 gravid females. The mean harvest rate (±SD) was 12 ± 6 fish/fisher-day effort. Exploitation estimates ranged between 19% and 40% during the 5-d seasons. Catch declined as the season progressed at Pool 13 and with a time lag at Ozark Lake. The short-term special seasons comprised 11–22% of the Arkansas statewide roe harvest for 2003, 2004, and 2006. The 5-d special season comprised 63% of the roe and 32% of the gravid females harvested for the 150-d Ozark Lake 2006–2007 season. A total of 27 citations were written for illegal activities, and bycatch mortality was a serious management concern at the 2006 Pool 13 season. Check stations provided a valuable management tool for accurately determining harvest and exploitation, and the brief special seasons allowed for controlled, monitored, and limited harvest. Illegal activities and large increases in the number of fishers entering the fishery were major threats to management for a sustainable roe fishery.

APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "624.151 32"

Трошина, Е. А., Н. М. Платонова, М. П. Исаева, and Н. П. Маколина. "РАСПРОСТРАНЕННОСТЬ АУТОИММУННЫХ ЗАБОЛЕВАНИЙ ЩИТОВИДНОЙ ЖЕЛЕЗЫ В УСЛОВИЯХ ЛЕГКОГО ЙОДНОГО ДЕФИЦИТА." In X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-201.

Full text

Abstract:

Самыми частыми причинами развития патологии ЩЖ являются нарушение аутоиммунитета и недостаточная йодная обеспеченность. Однако, взаимовлияние аутоиммунного и йододефицитного факторов на ткань ЩЖ остается предметом дискуссий и требует проведения исследований, направленных на оценку распространенности и патогенетических механизмов развития аутоиммунной патологий ЩЖ в условиях йодного дефицита для уточнения основ коморбидности. ЦЕЛЬ: оценка распространенности аутоиммунного тиреоидита в регионах йодного дефицита легкой степени тяжести. Материалы и методы: исследование проводилось в 3 районах Тульской области (n=286) и 4 регионах Чеченской Республики (n=318). Объем исследования – 604 участника старше 18 лет. Обследование включало: сбор анамнеза и анкетирование; физикальный осмотр врача-эндокринолога; УЗ-исследование ЩЖ (УЗИ ЩЖ); определение в сыворотки крови уровней тиреотропного гормона (ТТГ), свободных фракций тироксина (св.Т4) и трийодтиронина (св.Т3), антител к тиреопероксидазе (АТ-ТПО); Обследование выполнено в рамках работ по гранту РНФ № 22-15-00135 «Научное обоснование, разработка и внедрение новых технологий диагностики коморбидных йододефицитных и аутоиммунных заболеваний щитовидной железы, в том числе с использованием возможностей искусственного интеллекта». РЕЗУЛЬТАТЫ: по результатам обследования 604 человек распространенность структурных изменений ЩЖ по данным УЗИ ЩЖ составила 79,9% (n=254) в Чеченской Республике и 52,8% (n=151) в Тульской области. Из них УЗ-признаки АИТ выявлены у 25,2% (n=64) и 39% (n=59) соответственно. Гипотиреоз в исходе АИТ составил 13% (n=33) в структуре общей патологии ЩЖ Чеченской Республики и 13,2 % (n=20) в Тульской области. Распространенность повышенного титра АТ к ТПО в сыворотке крови при наличии нормальной функции ЩЖ составила 16,67% (n=53) в Чеченской Республике и 15,7% (n=45) в Тульской области. Сочетание аутоиммунной и узловой патологии ЩЖ встречается в 12,6% (n=32) случаев общей распространенности структурной патологии ЩЖ Чеченской Республики и 11,3% (n=17) случаев - в Тульской области. ВЫВОДЫ: по данным проведенного обследования в регионах с подтвержденным йододефицитом легкой степени тяжести основная часть структурных изменений ЩЖ приходится на диффузные и узловые зобные формы. Распространенность аутоиммунных изменений ЩЖ и носительства АТ-ТПО при сохранной её функции составляет 13-39%. Необходимо проведение дальнейших исследований, направленных на мониторинг распространенности и структуры тиреоидной патологии с выделением доли коморбидной патологии ЩЖ, в условиях модификации йодной обеспеченности населения региона с целью изучения аспектов взаимовлияния факторов развития заболеваний ЩЖ.

APA, Harvard, Vancouver, ISO, and other styles

Hosseini, Hamid, Dong Kim, Serge Toxopeus, Matteo Diez, and Frederick Stern. "CFD and Potential Flow Simulations of Fully Appended Free Running 5415M in Irregular Waves Hamid." In SNAME 5th World Maritime Technology Conference. SNAME, 2015. http://dx.doi.org/10.5957/wmtc-2015-152.

Full text

Abstract:

The capabilities of CFD and PF methods are assessed for course keeping of 5415M advancing at a Froude number of 0.248 in irregular waves with JONSWAP spectrum for various wave headings. CFD simulations are conducted with N=32 wave components for the wave headings of 0, 45, 90, 105, 180 deg. An additional beam wave simulation is also conducted using N=1000 components. PF simulations are conducted using N=400 wave components for three wave headings (0, 45 and 90 deg). A PF beam wave simulation is also performed using a similar but different rudder controller. The results are validated against experimental data for the validation variables, i.e. 6DOF motions and wave elevation. The validation study focuses on the statistics of the time series (addressed as primary variables), as well as height and mean-crossing period (addressed as secondary variables). RAOs of motions are also investigated. Subseries and time series theories for primary variables and bootstrap method for secondary variables are applied in order to estimate uncertainties and evaluate validation. The rudder controller study showed the predictions do not depend strongly on the controller setting as all variables excluding the yaw motion vary by less than 4%. For wave elevations, the average CFD and PF uncertainties over all headings were close to EFD and errors were comparable. More wave components could reduce the CFD wave uncertainties for the beam wave case. For motions/velocities in beam waves, uncertainties for CFD with N=1000 and PF were also close to EFD. CFD and PF average error values for the primary variables were 26%D and 57%D, respectively. The errors were large for the secondary variables. The effect of number of wave components on the errors of motion/velocity was 13%D on average. The errors of the primary variables varied by <6.4%D. The largest effect of number of wave components on the primary variable errors was for the roll and yaw motion (~11%D) whereas the largest effect on the secondary variable errors was for the surge velocity. Considering all wave headings, average uncertainty values for both CFD and PF over all the variables were close to EFD such that average validation uncertainty is about 39%D. The overall average error values were similar for CFD and PF, at about 64%D. The trends versus wave headings for statistical results of the primary and secondary variables and RAOs were often well predicted by both CFD and PF. RAOs were similar with the ones from regular waves, available only at a single frequency for head and beam cases. Roll RAOs showed resonance in near beam wave conditions resulting in large roll motions, particularly for the case with passive fins at 105 deg wave heading.

APA, Harvard, Vancouver, ISO, and other styles

"PV-063 - MOTIVO DE INGRESO EN PACIENTES DE PERFIL DUAL QUE INGRESAN EN LA UNIDAD DE AGUDOS DEL HOSPITAL DE MATARÓ DURANTE 3 MESES." In 24 CONGRESO DE LA SOCIEDAD ESPAÑOLA DE PATOLOGÍA DUAL. SEPD, 2022. http://dx.doi.org/10.17579/abstractbooksepd2022.pv063.

Full text

Abstract:

Objetivos Describir diagnósticos de pacientes de perfil-Dual que ingresan en la Unidad de agudos de psiquiatría del H. de Mataró de octubre a diciembre 2021. Material y métodos Todos los pacientes que ingresaron y tenían características duales incluidos en una base de datos que permite analizar los motivos principales de ingreso y diagnósticos. Resultados y conclusiones Del total de 195 ingresos en UHA un 27.1% (n=52) eran de perfil dual, el 61.5% de los pacientes hombres (n=32) y con una media de edad de 50.5 años. El 98% (n=51) fueron ingresos urgentes. Motivos de ingreso: Episodio psicótico 36.5% (n=19) y Episodio maniforme-con sintomatología-psicótica 19.2% (n=10). Ideación autolítica 15.4% (n=8) e Intento autolítico 5.7% (n=3). Episodio depresivo-adaptativo 7.6% (n=4) y desintoxicación urgente 5.7% (n=3). Ingresos previos 59.6% (n=31), con una media de 2.5 ingresos por paciente; el 23% (n=12) ingreso previo de adicciones, media de 0.71 por paciente. Durante 6 meses previos, no realizaban adecuadamente el seguimiento 67% (n=35) ni el tratamiento 62% (n=32). Ingreso involuntario 60% (n=31), estancia media de 15.1 días, y precisan contención mecánica 37% (n=16). Alta médica 93% (n=40) y voluntaria 5% (n=2). Diagnósticos al alta: T. psicótico-inducido 20.9% (n=9), T. bipolar 18.6% (n=8), T. personalidad 18.6% (n=8); Esquizofrenia 14% (n=6), T. esquizoafectivo 14%, T. psicótico NE 7% (n=3), Distímia 2.3% (n=1), T. adaptativo 2.3%, Deterioro cognitivo 2.3%. Comorbilidad con Trastorno de la personalidad el 74.4% (n=32), T. límite 23.2% (n=10), histrioniforme 18.6% (n=8) y antisocial en 16.3% (n=7). Conclusiones Importante peso de T. psicóticos y afectivos e ideaciones-intentos autolíticos. Mayor gravedad (ingresos involuntarios, contención mecánica), y largo recorrido en la red de salud mental con menor recorrido en la de adicciones.

APA, Harvard, Vancouver, ISO, and other styles

Fontes, Juliana de Alencar, Gabriel Praxedes Freire, Gabriel Nascimento, and Pedro Antônio Pereira de Jesus. "Relationship between sodium disturbances on admission, stroke severity (NIHSS) and functional outcome (mRs)." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.648.

Full text

Abstract:

Background: Hyponatremia is the most common electrolyte disturbance in hospitalized patients and is associated with several unfavorable outcomes, as it promotes cerebral edema and consequent intracranial hypertension. As isn’t clear if there is a causal relationship or if it is only a marker of severity, we described and analyzed the association between sodium disorders, especially hyponatremia, with the severity level of the stroke and the functional condition of discharge of these patients. Methods: We did a cross-sectional study with patients admitted to a stroke unit of a reference hospital in Salvador-Ba between 11/2017 and 03/2020 included in the DISPASS cohort. We classify hyponatremia as serum sodium 145mEq / L. To analyze the association between the variables, Fisher’s exact test was performed. Results: We analyzed 399 patients whose mean age was 62. The mean sodium on admission was 138.2 mEq / L, with 56 patients (14%) with hyponatremia and 11 (3%) with hypernatremia. Among those who had sodium disorders at admission (67), 32 had moderate NIHSS, 24 severe / very severe NIHSS and 11 had mild NIHSS. X² = 2.48, p = 0.443. In addition, of these 67 patients, 13 were discharged and still needed help in daily activities and to walk (mRs 4), 15 were discharged restricted to bed (mRs 5) and 6 died during hospitalization (mRs 6). Therefore, of the 17% who had sodium disorder at admission, more than half had a poor functional outcome. Among those who had hyponatremia (56), 35.7% (20) had severe / very severe stroke, 46.4% (26) had a moderate degree, while only 10 had a mild degree. X² = 1.91, p = 0.53. Conclusions: Although the Fisher Test did not show a significant association (p> 0.05), the frequencies of patients with sodium disorders at admission and classified as having high stroke severity were presented with relevant values, so it is important to carry out further studies to investigate the relationship of these variables.

APA, Harvard, Vancouver, ISO, and other styles

Петров, А. В., and А. Н. Гаврилова. "ГЛИКИРОВАННЫЙ ГЕМОГЛОБИН И САМОКОНТРОЛЬ ГЛИКЕМИИ У ПАЦИЕНТОВ С САХАРНЫМ ДИАБЕТОМ 2 ТИПА – УЧАСТНИКОВ ШКОЛ ДИАБЕТА." In X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-105.

Full text

Abstract:

ЦЕЛЬ: изучить параметры компенсации углеводного обмена и связанные с ними факторы у пациентов, проходивших обучение в школах диабета и иных образовательных мероприятиях РООИ «Нижегородская диабетическая лига». МАТЕРИАЛЫ И МЕТОДЫ: проведено анкетирование и оценка гликированного гемоглобина (НвА1с) у 121 пациента с сахарным диабетом 2 типа, обучавшихся в школе диабета или участвовавших в одноднев- ных образовательных мероприятиях РООИ «Нижегородская диабетическая лига». Оценивался анамнез сахарного диабета и его терапии, самоконтроль. Данные приведены в формате M±SD, уровень статисти- ческой значимости принят как р<0.05 РЕЗУЛЬТАТЫ: из 121 обследованного пациента 89% составили женщины, средний возраст 65±11,5 лет; средняя длительность диабета 9±7,0 лет. 68% пациентов получали терапию метформином; 24% - препара- тами сульфонилмочевины; 10% - глиптинами; 7,4% (9 чел.) – глифлозинами; 22% - препаратами инсулина. Тест на гликированный гемоглобин был выполнен у 84 пациентов (69% обследованных), средний уро- вень составил 7,6±1,94%. Доля пациентов с НвА1с >8% была равна 32%, эти пациенты не имели достовер- ных отличий по возрасту (68±10,6 пр.63±13,5 лет, р=0,09) и, закономерно, отличались большей длительно- стью диабета (12±6,7 пр. 7±6,6 лет, р=0,002). Из 11 мужчин НвА1с более 8% отмечался у 9 (82%), тогда как среди женщин такое повышение было зарегистрировано в меньшинстве случаев (26%, р=0,0003). Среди пациентов с уровнем НвА1с более 8% 30% получали инсулинотерапию, тогда как в группе с меньшими значениями инсулинотерапия проводилась достоверно реже (7%, р=0,006). По результатам опросника регулярный самоконтроль не менее 1 дня в неделю проводили 70% паци- ентов, среди них 63% измеряли уровень гликемии как натощак, так и в течение дня. 57 пациентов (69%), проводивших регулярный самоконтроль, сообщили при анкетировании данные о средних показателях гликемии. В наибольшей степени с уровнем НвА1с коррелировал средний показатель гликемии при са- моконтроле в течение дня (R=0.75 p<0.0001), для средней гликемии натощак коэффициент корреляции был меньше (R=0.57 p<0.0001). Доля пациентов, проводивших регулярный самоконтроль, не отличалась существенно между группами, разделенными по уровню НвА1с 8%. При этом у пациентов с высокими уровнями НвА1с при самоконтроле регистрировались высокие значения гликемии – натощак 9,1±2,6 пр. 6,4±1,1 ммоль/л, р<0,0001; в течение дня 12,5±2,4 пр. 8,6±1,1 ммоль/л, р<0,0001. ВЫВОДЫ: среди людей с диабетом 2 типа, принимавших участие в образовательных мероприятиях региональной общественной организации пациентов с сахарным диабетом, плохой гликемический кон- троль отмечался не менее чем в 1/3 случаев. Мужчины с сахарным диабетом в большей степени страдают от низкого уровня знаний и мотивации в отношении сохранения здоровья, при этом имея низкий уровень участия в обучении. Активное привлечение мужчин с сахарным диабетом 2го типа может являться одним из приоритетов в организации обучения. Значительная доля пациентов не осуществляет регулярного самоконтроля гликемии, однако даже при его проведении сохраняется риск плохого управления гликемией, связанный, по-видимому, с инерцией в интенсификации сахароснижающей терапии и игнорированием высоких показателей гликемии по дан- ным самоконтроля.

APA, Harvard, Vancouver, ISO, and other styles

Семикова, Г. В., С. В. Дора, and З. В. Швец. "ДИНАМИКА ПОКАЗАТЕЛЕЙ ИНСУЛИНОРЕЗИСТЕНТНОСТИ И РЕПРОДУКТИВНЫХ НАРУШЕНИЙ У ПАЦИЕНТОК С ОЖИРЕНИЕМ ПОСЛЕ ВЫПОЛНЕНИЯ РУКАВНОЙ ГАСТРОПЛАСТИКИ." In X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-158.

Full text

Abstract:

ЦЕЛЬ: оценить влияние рукавной гастропластики на менструальный цикл и уровень половых гормонов у пациенток репродуктивного возраста с ожирением МАТЕРИАЛЫ И МЕТОДЫ: проведено наблюдательное проспективное исследование 32 пациенток с индексом массы тела (ИМТ) ≥ 35 кг/м2 в возрасте от 19 до 38 лет с различными нарушениями менстру- ального цикла (НМЦ). Пациенткам выполняли рукавную гастропластику (РГ) по стандартной методике. Исходно и через 1 год после операции оценивали ИМТ, на 3-5 день менструального цикла при его наличии определяли уровень гонадотропных гормонов: фолликулостимулирующего (ФСГ) и лютеинизирующего (ЛГ), уровень общего эстрадиола, свободного тестостерона и пролактина, а также антимюллерова гормона (АМГ) как маркера овариального резерва. Уровень прогестерона определяли на 21-23 день менструаль- ного цикла (при его наличии). Индекс инсулинорезистентности НОМА-IR рассчитывали по стандартной формуле, за инсулинорезистентность принимали значение более 2,7. РЕЗУЛЬТАТЫ: медиана возраста пациенток составила 29 (22 – 35) лет, ИМТ исходно - 38,8 кг/м2 (36,2 – 40,2). Структура МНЦ была представлена следующим образом: олигоменорея выявлялась у 28,1% па- циенток (n = 9), аномальные маточные кровотечения у 53,1% пациенток, (n = 17), аменорея на протяжении как минимум 6 месяцев до оперативного вмешательства – у 18,8% пациенток (n = 6). Исходно НОМА-IR был равен 5,4 (3,2 – 8,1), что свидетельствует об инсулинорезистентности; только у одной пациентки HOMA-IR был менее 2,7. Исходно уровень ФСГ составил 4,6 мМЕ/мл (3,0 – 6,4), ЛГ – 11,2 мМЕ/мл (8,4 – 15,2). Уровень эстрадиола общего составил 362 пг/мл (318 – 414), свободного тестостерона – 5,7 пг/мл (4,2 – 6,8). Уровень пролактина был равен 448 мМЕ/л (316 – 522). Уровень прогестерона составил 12,3 нмоль/л (7,3 – 18,8). Уровень АМГ составил 2,9 нг/мл (1,9 - 3,5). Значимых различий в уровне описанных гормонов у пациенток с различными НМЦ выявлено не было, также не выявлялось корреляции с возрастом и ИМТ. Через 1 год после РГ у всех пациенток ИМТ снизился до 27,3 кг/м2 (24,6 – 29,1), р < 0,001. НОМА-IR был ниже исходных значений: 2,8 (1,6 – 3,6). У 22 женщин произошла нормализация менструального цикла; через 1 год после операции у 4 женщин сохранялись аномальные маточные кровотечения, у 3 – олигомено- рея, у 3 – аменорея. Описанные пациентки были старше, однако различия в возрасте не были статистически значимы. Уровень ФСГ через 1 год после РГ повысился и составил 11,6 мМЕ/мл (8,2 – 15,6), р = 0,042; уровень ЛГ снизился по сравнению с исходными значениями до 6,4 мМЕ/мл (3,2 – 9,1), р = 0,048. Уровень общего эстрадиола снизился до 320 пг/мл (265 – 373), однако различия статистически не значимы. Свободный тестостерон был ниже исходных значений – 3,2 пг/мл (2,5 – 4,8), р = 0,034. Уровень пролактина значимых изменений не претерпел. Уровень АМГ через 1 год после операции возрос до 3,5 нг/мл (2,9 – 4,5), р = 0,042; уровень прогестерона – до 26,3 нмоль/л (15 – 42), р = 0,024. ВЫВОДЫ: выполнение РГ у пациенток с ожирением приводит к снижению инсулинорезистентности, нормализации менструальной функции у большинства пациенток, что сопровождается повышением уровня АМГ, изменением соотношения гонадотропных гормонов и уменьшением уровня свободного тестостерона, а также повышением уровня прогестерона.

APA, Harvard, Vancouver, ISO, and other styles

Gao, M., and Y. Cao. "Heat Spreaders for High-Power Electronics Employing Boiling Mechanisms in a Narrow Space." In ASME 1998 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1998. http://dx.doi.org/10.1115/imece1998-0879.

Full text

Abstract:

Abstract To achieve a high heat-flux level and reduce manufacturing costs associated with conventional heat pipes, the concept of network heat spreaders employing boiling heat-transfer mechanism in a narrow space has been proposed and several flat-plate wickless heat spreaders have been designed and fabricated. The heat spreaders have been tested under different working conditions and orientations relative to the gravity with very good results. The previously tested network heat spreaders, however, were based on plates with a relatively large size for general heat spreading purposes. In the present study, network heat spreaders with overall dimensions of 78 × 62 × 3.2 mm are designed and fabricated. The spreaders with this size are intended for use as heat sinks of high-power electronic components. External cooling fins are attached to enhance air-cooling heat transfer rate. The network heat spreaders are tested under various working conditions with water as the working fluid. The maximum heat input rate achieved is about 150 W with a corresponding heat flux of 60 W/cm2. Compared to the performance of a solid copper plate having the same overall size as the spreader, the maximum temperature difference over the surface is reduced from about 32 °C to 3.3 °C. The heat transfer performance of the spreader is also largely dependent on the filling ratio of the working fluid and the boiling heat transfer in the narrow space. For these reasons, boiling heat transfer mechanisms in a narrow space are analyzed, and a spreader design that would improve the performance in a horizontal position is described.

APA, Harvard, Vancouver, ISO, and other styles

Крюкова, И. В., Е. Ю. Полякова, and А. В. Ильина. "ЭПИДЕМИОЛОГИЯ ПЕРВИЧНОГО ГИПЕРПАРАТИРЕОЗА В МОСКОВСКОЙ ОБЛАСТИ: РЕЗУЛЬТАТЫ ВЕДЕНИЯ РЕГИСТРА БОЛЬНЫХ НА КОНЕЦ 2022 ГОДА." In X (XXIX) НАЦИОНАЛЬНЫЙ КОНГРЕСС ЭНДОКРИНОЛОГОВ с международным участием «Персонализированная медицина и практическое здравоохранение». ФГБУ «НМИЦ эндокринологии» Минздрава России, 2023. http://dx.doi.org/10.14341/cong23-26.05.23-26.

Full text

Abstract:

ЦЕЛЬ: оценить результаты ведения регистра первичного гиперпаратиреоза (ПГПТ) в Московской об- ласти (МО) на конец 2022 года в рамках всероссийской онлайн-версии базы данных больных с ПГПТ. МАТЕРИАЛЫ И МЕТОДЫ: проведен анализ регистра ПГПТ, работа с которым в МО начата с момента его разработки в конце 2016 года. Критерием включения в регистр являются больные с лабораторно подтвержденным ПГПТ: при уровне ПТГ превышающем верхнюю границу референсных лабораторных значений и повышенном или верхненормальном уровне кальция сыворотки крови, выявленном дважды. Критерии исключения: больные с вторичным и третичным гиперпаратиреозом, наследственной гипокаль- циурической гиперкальциемией и гиперкальциемией, не связанной с повышением ПТГ. Данные регистра в МО оценивались на конец декабря 2022 года. РЕЗУЛЬТАТЫ: всего в регистр МО на момент исследования были внесены данные 1112 больных ПГПТ: 1046 женщин и 66 мужчин. Средний возраст пациентов составил 67,08±10,9 лет (мужчин – 65,5±14,5 лет, женщин – 67,02±10,8 лет), средний возраст на момент дебюта заболевания – 62,04±10,8 лет (у мужчин – 59,9±15,2 лет, у женщин – 62,1±10,5 лет). Первые симптомы заболевания у больных выявлялись в среднем в возрасте 59,2±11,5 лет (в 52,5±12,3 лет у мужчин и в 58,8±11,2 лет у женщин). По данным регистра ПГПТ в МО в 2015 году было выявлено 60 новых случаев заболевания. С 2016 года отмечался значительный рост выявляемости ПГПТ – 133 больных, в 2017 году – 147 больных, в 2018 году – 141 больной, в 2019 году – 190 больных, в 2020 году – 131 больной, в 2021 – 108 больных, в 2022 году – 47 больных. В активной фазе заболевания на момент оценки находились 622 (55,88%) больных (41 (3,7%) мужчина и 581 (52,2%) женщина), ремиссия подтверждена у 456 (40,97%) пациентов (23 (2,1%) мужчин и 433 (38,9%) женщин) и рецидив заболевания отмечался у 34 (3,05%) человек (2 (0,2%) мужчин и 32 (2,9%) женщин). По результатам морфологического исследования атипическая аденома была диагностирована у 27 (5,5%) человек (3 (0,6%) мужчин и 24 (4,9%) женщин, карцинома – у 12 (2,4%) человек (1 (0,2%) мужчины и 11 (2,2%) женщин). Частота характерных клинических проявлений ПГПТ у больных составила: патология ЖКТ у 68,6% боль- ных (763/1112), патология почек – у 61,2% (681/1112), остеопороз – у 54% (600/1112), низкотравматические переломы – у 26% (289/1112). Также у больных ПГПТ часто встречались заболевания сердечно-сосудистой системы – 65,1% (724/1112) и артериальная гипертензия – 61,3% (682/1112). Средние значения основных лабораторных параметров в зависимости от фазы заболевания: у боль- ных в активной фазе ПТГ – 134±1102,2 пг/мл, общий кальций – 2,74±0,2 ммоль/л, в ремиссии: ПТГ – 46±21,7 пг/мл, общий кальций крови – 2,34±0,17ммоль/л. ВЫВОДЫ: ведение регистра больных ПГПТ позволяет оценить динамику выявляемости заболевания, лабораторные показатели, в том числе в зависимости от фазы заболевания, частоту осложнений, случаи рецидива. По данным регистра в МО последние годы отмечаются стабильно высокие показатели выявля- емости ПГПТ, значительный процент костных и висцеральных осложнений. При это, вероятно, дальнейшая активная работа по выявлению больных с ПГПТ в МО будет способствовать увеличению доли пациентов с бессимптомными формами заболевания. 23

APA, Harvard, Vancouver, ISO, and other styles

Zaitoun, Alain, Arnaud Templier, Jerome Bouillot, Nazanin Salehi, Budi Rivai Wijaya, Agung Arief Wijaya, Arief Witjaksono, and Wery Kurniadi. "Successful Polymer Treatment of Offshore Oil Well Suffering from Sand Production Problems." In International Petroleum Technology Conference. IPTC, 2021. http://dx.doi.org/10.2523/iptc-21171-ms.

Full text

Abstract:

Abstract Many fields in South East Asia are suffering from sand production problems due to sensitive sandstone formation. Sand production increases with time and increasing water production. The production of sand induces loss of production, due to sand accumulation in the wellbore, and heavy operational costs such as frequent sand cleaning jobs, pump replacements, replacement of surface and downhole equipment, etc. An original sand control technology consisting of polymers injection and already deployed in gas wells, has been successfully tested in an offshore oil well. The technology utilizes polymers having a natural tendency to coat the surface of the pores by a thin gel-like film of around 1 µm. Contrary to the use of resins which aim at creating a solid around the wellbore, the polymer system maintains the center of the pores fully open for fluid flow, thus preserving oil or gas permeability while often reducing water permeability (a property known as RPM for Relative Permeability Modification). The advantage of such system is that the product can be injected in the bullhead mode and often, a reduction of water production is observed along the drop in sand production. In gas wells, the treatment lasts around 4 years and can be renewed periodically. A lab work was undertaken to screen out a polymer product well suited to actual reservoir conditions. We conducted bulk tests to evaluate product interaction on reservoir sand samples, and corefloods to evaluate in-situ performances. Treatment volume and concentration were determined after lab test. One of "Oil Well" candidate is located in Arjuna Field, offshore Indonesia. Downhole conditions are: Temperature = 178°F, salinity = 18000 ppmTDS, permeability = 140-300mD, two perforated intervals with total thickness of 67ft (ft-MD) with 38 ft Average Netpay Thickness, production rate = 800 bfpd. The well is under gas lift and needed to be cleaned out every 3 months because of sand accumulation. Polymer treatment was performed in two stages (bottom, then upper interval). A total volume of 150 m3 of polymer solution was pumped. Immediately after treatment, sand cut dropped from 1% to almost 0%. This enabled increasing the drawdown from 32/64’’ choke to 40/64’’, keeping the production sand free and sustained with time. This field test confirms the feasibility of the original sand control polymer technology both in gas wells and in oil wells, which opens high possibilities in the future.

APA, Harvard, Vancouver, ISO, and other styles

Najim ABDULLAH, Rawaa, Mustafa jawad KADHAM, and Saif Ali Mohammed HUSSEIN. "PREVALENCE OF SYPHILIS AMONG BLOOD VOLUNTEERS IN BAGHDAD PROVINCE / IRAQ." In VI.International Scientific Congress of Pure,Applied and Technological Sciences. Rimar Academy, 2022. http://dx.doi.org/10.47832/minarcongress6-14.

Full text

Abstract:

The bacterium Treponema pallidum subspecies pallidum causes syphilis, a sexually and blood-transmitted illness (STD). The signs and symptoms of syphilis vary according on the stage of the illness (primary, secondary, latent, and tertiary). The goal of this study is to use serological and immunological testing to evaluate the prevalence of syphilis among blood donors in Baghdad province. The current study was done on a total of 28287 blood donors at the main blood bank in Baghdad who were tested between April 2020 and March 2021. They ranged in age from 20 to 75 years and were screened throughout the study period between April 2020 and March 2021. Serum, plasma and whole blood samples were collected, tested for IgG,IgA and IgM by ELISA. The results of the epidemiological study revealed that 200 instances of syphilis were found among 28287 blood samples donated by volunteers, with no signs of the disease. There were 189 men (94.5%) and 11 women (5.5%), resulting in a male to female ratio of 17:1. According to the findings of the current study, the incidence of syphilis among blood donors in both sexes varied in proportion to the donors' socio-demographic parameters, with a higher frequency in men. the study shows the following percentages: Unemployed / jobless 139 (69. 5 percent), governments 35 (17.5%), merchants 12 (6%), farmers 11 (5.5%), and students 3 (1.5%). The majority were 85 (42.5 percent), with primary study accounting for 75 (37.5%), secondary study 31 (15.5%), tertiary 6 (3%), and university graduates 3 (1.5%). The findings indicated that married people had 154 (77%) more infections than unmarried people 46 (23%). The individuals' ABO profiles were 92 (46%) O, 64 (32%) A, 33 (16.5%) B, and 11 (5.5%) AB. Syphilis serology had been performed and showed positive treponemal IgG, IgA & IgM by ELISA, The showed that results all 200 samples of donor's blood were positive for TPHA test.

APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "624.151 32"

Díaz, Jorge Luis, Ángela Patricia Alarcón, Victor Zein Rizo, Alejandra Velásquez, Diana Marcela Walteros, Helena Patricia Salas, and Franklyn Edwin Prieto. Investigación de brote de COVID-19 en repatriados desde Estados Unidos a Cundinamarca, Colombia, abril 2020. Instituto Nacional de Salud, July 2021. http://dx.doi.org/10.33610/01229907.2021v3n3a4.

Full text

Abstract:

Introducción: con base en el aumento y circulación sostenida en países como Francia, España, Canadá, Estados Unidos de América, Brasil e Italia el gobierno de Colombia en articulación con otros estados decidió realizar vuelos humanitarios desde y hacia países con transmisión activa bajo procedimientos de control de riesgos y bioseguridad. El objetivo de este estudio fue describir un brote de COVID-19 en un grupo de connacionales repatriados desde Estados Unidos a Colombia quienes permanecieron en aislamiento preventivo en un municipio de Cundinamarca, en abril de 2020. Materiales y métodos: estudio descriptivo de un brote por COVID-19, enmarcado en la metodología propuesta por los CDC, a través de un análisis de frecuencias, donde se evaluaron 64 connacionales, contactos estrechos, reportes de muestras y las zonas de aislamiento. Resultados: se confirmaron 24 casos positivos para SARS-CoV-2, 23 en connacionales y un caso en el personal de logística. Se encontraron 111 contactos estrechos, con una tasa de ataque del 21,62 %. La edad promedio de las personas encargadas de logística fue de 32 años, con una DE 10,9 (mínima de 19 y máxima de 64 años) de los cuales el 70,2 % (33) eran hombres y el 29,78 % (14) sin antecedentes médicos de importancia. Conclusiones: la trasmisión del evento se relacionó con el no cumplimiento del distanciamiento social, uso adecuado de elementos de bioseguridad y uso de zonas comunes de forma permanente.

APA, Harvard, Vancouver, ISO, and other styles

Huijser, Marcel, and S. C. Getty. Modified jump-outs for white-tailed deer and mule deer. Nevada Department of Transportation, September 2022. http://dx.doi.org/10.15788/ndot2018.2022.

Full text

Abstract:

The height of the jump-outs should be low enough for the target species to readily jump down to the safe side, or the habitat side, of the fence. At the same time, the jump-outs should be high enough to discourage animals that are on the habitat side of the fence from jumping up into the fenced road corridor. Previous research along US Hwy 93 North in Montana showed that only about 32% of the mule deer and about 7% of the white-tailed deer that appeared on top of the jump-outs, jumped down to safety. For this project, 10 of the jump-outs along US Hwy 93 North were lowered in height and provided with a bar on top. The height of the bars (made from rebar) and their setback from the vertical face of the jump-outs was adjustable and the researchers applied 4 different treatments: 2 different heights (18 and 15 inches) and 3 different setbacks (4, 12, and 15 inches). The overall effectiveness of the lowered jump-outs in allowing white-tailed deer to jump down, regardless of the height and setback of the bar, was only just above 5% (no improvement). For mule deer the effectiveness of the lowered jump-outs in allowing them to jump down, regardless of the height and setback of the bar, was about 64% (this was double the effectiveness of non-modified jump-outs).

APA, Harvard, Vancouver, ISO, and other styles

Rodriguez, Dirk, and Cameron Williams. Channel Islands Nation Park: Terrestrial vegetation monitoring annual report - 2016. National Park Service, August 2022. http://dx.doi.org/10.36967/2293561.

Full text

Abstract:

This report presents the data collected in 2016 as part of the long-term terrestrial vegetation monitoring program at Channel Islands National Park. The purposes of the monitoring program are to document the long-term trends in the major vegetation communities within the park. The data collected are from 30 m point-line intercept transects. In the past, each transect was sampled annually. However, beginning in 2012 the program began adding randomly located transects to improve the representativeness of the sampling, and transitioned to a rotating panel design. Now only a core subset of the transects are read annually. Non-core transects are assigned to one of four panels, and those transects are read only once every four years. A summary analysis of the 2016 data shows that: 165 transects were read. The 165 transects were distributed across all five islands: Santa Rosa Island (n = 87), Santa Cruz Island (n = 33), Santa Barbara Island (n = 18), Anacapa Island (n = 9) and San Miguel Island (n = 11). Relative native plant cover averaged 63% across all islands and sampled communities while absolute native plant cover averaged 32%. Among plant communities, relative percent native cover ranged from a low of 1% in seablite scrub to a high of 98% in oak woodland. In general, the number of vegetation data points recorded per transect positively correlates with average rainfall, which is reflected in the number of “hits” or transect points intersecting vegetation. When precipitation declined there is a corresponding drop in the number of hits. In 2016, however this was not the case. Even though rainfall increased as compared to the previous 4 years (18.99 inches in 2016 vs an average of 6.32 for the previous 4 years), the average number of hits was only 64. To put this into perspective, the highest average number of hits was 240 in 1993, an El Niño year of high precipitation. The number of vegetation communities sampled varied by island with the larger islands having more communities. In 2016, there were 15 communities sampled on Santa Rosa Island, 12 communities on Santa Cruz Island, 7 communities on San Miguel Island, 7 communities on Santa Barbara Island, and 7 communities on Anacapa Island. Twenty-six vegetation types were sampled in 2016. Of these, 13 occurred on more than one island. The most commonly shared community was Valley/Foothill grassland which was found in one form or another on all five islands within the park. The next most commonly shared communities were coastal sage scrub and coastal scrub, which were found on four islands. Coastal bluff scrub and coreopsis scrub were monitored on three islands. Four communities—ironwood, mixed woodland, oak woodland, riparian, and seacliff scrub—were monitored on two islands, and 12 communities—Torrey pine woodland, shrub savannah, seablite scrub, Santa Cruz Island pine, perennial iceplant, lupine scrub, fennel, coastal strand, coastal marsh, cactus scrub, boxthorn scrub, barren, and Baccharis scrub—were each monitored on one island.

APA, Harvard, Vancouver, ISO, and other styles

Chou, Roger, Jesse Wagner, Azrah Y. Ahmed, Benjamin J. Morasco, Devan Kansagara, Shelley Selph, Rebecca Holmes, and Rongwei Fu. Living Systematic Review on Cannabis and Other Plant-Based Treatments for iii Chronic Pain: 2022 Update. Agency for Healthcare Research and Quality (AHRQ), September 2022. http://dx.doi.org/10.23970/ahrqepccer250update2022.

Full text

Abstract:

Objectives. To update the evidence on benefits and harms of cannabinoids and similar plant-based compounds to treat chronic pain using a living systematic review approach. Data sources. Ovid® MEDLINE®, PsycINFO®, Embase®, the Cochrane Library, and SCOPUS® databases; reference lists of included studies; and submissions received after Federal Register request were searched to April 4, 2022. Review methods. Using dual review, we screened search results for randomized controlled trials (RCTs) and observational studies of patients with chronic pain evaluating cannabis, kratom, and similar compounds with any comparison group and at least 1 month of treatment or followup. Dual review was used to abstract study data, assess study-level risk of bias, and rate the strength of evidence (SOE). Prioritized outcomes included pain, overall function, and adverse events. We grouped studies that assessed tetrahydrocannabinol (THC) and/or cannabidiol (CBD) based on their THC to CBD ratio and categorized them as comparable THC to CBD ratio, high-THC to CBD ratio, and low-THC to CBD ratio. We also grouped studies by whether the product was a whole-plant product (cannabis), cannabinoids extracted or purified from a whole plant, or a synthetic product. We conducted meta-analyses using the profile likelihood random effects model and assessed between-study heterogeneity using Cochran’s Q statistic chi square test and the I2 statistic. Magnitude of benefit was categorized as no effect or small, moderate, and large effects. Results. From 3,283 abstracts, 21 RCTs (N=1,905) and 8 observational studies (N=13,769) assessing different cannabinoids were included; none evaluated kratom. Studies were primarily short term, and 59 percent enrolled patients with neuropathic pain. Comparators were primarily placebo or usual care. The SOE was low unless otherwise noted. Compared with placebo, comparable THC to CBD ratio oral spray was associated with a small benefit in change in pain severity (7 RCTs, N=632, 0 to10 scale, mean difference [MD] −0.54, 95% confidence interval [CI] −0.95 to −0.19, I2=39%; SOE: moderate) and overall function (6 RCTs, N=616, 0 to 10 scale, MD −0.42, 95% CI −0.73 to −0.16, I2=32%). There was no effect on study withdrawals due to adverse events. There was a large increased risk of dizziness and sedation, and a moderate increased risk of nausea (dizziness: 6 RCTs, N=866, 31.0% vs. 8.0%, relative risk [RR] 3.57, 95% CI 2.42 to 5.60, I2=0%; sedation: 6 RCTs, N=866, 8.0% vs. 1.2%, RR 5.04, 95% CI 2.10 to 11.89, I2=0%; and nausea: 6 RCTs, N=866, 13% vs. 7.5%, RR 1.79, 95% CI 1.19 to 2.77, I2=0%). Synthetic products with high-THC to CBD ratios were associated with a moderate improvement in pain severity, a moderate increase in sedation, and a large increase in nausea (pain: 6 RCTs, N=390, 0 to 10 scale, MD −1.15, 95% CI −1.99 to −0.54, I2=48%; sedation: 3 RCTs, N=335, 19% vs. 10%, RR 1.73, 95% CI 1.03 to 4.63, I2=28%; nausea: 2 RCTs, N=302, 12.3% vs. 6.1%, RR 2.19, 95% CI 0.77 to 5.39; I²=0%). We also found moderate SOE for a large increased risk of dizziness (2 RCTs, 32% vs. 11%, RR 2.74, 95% CI 1.47 to 6.86, I2=40%). Extracted whole-plant products with high-THC to CBD ratios (oral) were associated with a large increased risk of study withdrawal due to adverse events (1 RCT, 13.9% vs. 5.7%, RR 3.12, 95% CI 1.54 to 6.33) and dizziness (1 RCT, 62.2% vs. 7.5%, RR 8.34, 95% CI 4.53 to 15.34); outcomes assessing benefit were not reported or insufficient. We observed a moderate improvement in pain severity when combining all studies of high-THC to CBD ratio (8 RCTs, N=684, MD −1.25, 95% CI −2.09 to −0.71, I2=58%; SOE: moderate). Evidence (including observational studies) on whole-plant cannabis, topical or oral CBD, low-THC to CBD, other cannabinoids, comparisons with active products or between cannabis-related products, and impact on use of opioids was insufficient to draw conclusions. Other important harms (psychosis, cannabis use disorder, and cognitive effects) were not reported. Conclusions. Low to moderate strength evidence suggests small to moderate improvements in pain (mostly neuropathic), and moderate to large increases in common adverse events (dizziness, sedation, nausea) with high- and comparable THC to CBD ratio extracted cannabinoids and synthetic products during short-term treatment (1 to 6 months); high-THC to CBD ratio products were also associated with increased risk of withdrawal due to adverse events. Evidence for whole-plant cannabis and other comparisons, outcomes, and plant-based compounds was unavailable or insufficient to draw conclusions. Small sample sizes, lack of evidence for moderate and long-term use and other key outcomes, such as other adverse events and impact on use of opioids during treatment, indicate that more research is needed.

APA, Harvard, Vancouver, ISO, and other styles

Chou, Roger, Azrah Y. Ahmed, Christina Bougatsos, Benjamin J. Morasco, Rebecca Holmes, Terran Gilbreath, and Rongwei Fu. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain: 2022 Update—Surveillance Report 2. Agency for Healthcare Research and Quality (AHRQ), January 2023. http://dx.doi.org/10.23970/ahrqepccer250.2022updatesr2.

Full text

Abstract:

Objectives. To update the evidence on benefits and harms of cannabinoids and similar plant-based compounds to treat chronic pain using a living systematic review approach. Data sources. Ovid® MEDLINE®, PsycINFO®, Embase®, the Cochrane Library, and SCOPUS® databases; reference lists of included studies; and submissions received after Federal Register request were searched to October 24, 2022. Review methods. Using dual review, we screened search results for randomized controlled trials (RCTs) and observational studies of patients with chronic pain evaluating cannabis, kratom, and similar compounds with any comparison group and at least 1 month of treatment or followup. Dual review was used to abstract study data, assess study-level risk of bias, and rate the strength of evidence (SOE). Prioritized outcomes included pain, overall function, and adverse events. We grouped studies that assessed tetrahydrocannabinol (THC) and/or cannabidiol (CBD) based on their THC to CBD ratio and categorized them as comparable THC to CBD ratio, high-THC to CBD ratio, and low-THC to CBD ratio. We also grouped studies by whether the product was a whole-plant product (cannabis), cannabinoids extracted or purified from a whole plant, or a synthetic product. We conducted meta-analyses using the profile likelihood random effects model and assessed between-study heterogeneity using Cochran’s Q statistic chi square test and the I2 statistic. Magnitude of benefit was categorized as no effect or small, moderate, and large effects. Results. From a total of 3,568 abstracts, 21 RCTs (N=1,905) and 9 observational studies (N=15,079) assessing different cannabinoids were included; none evaluated kratom. Studies were primarily short term, and 60 percent enrolled patients with neuropathic pain. Comparators were primarily placebo or usual care. The SOE was low unless otherwise noted. Compared with placebo, comparable THC to CBD ratio oral spray was associated with a small benefit in pain severity (7 RCTs, N=632, 0 to 10 scale, mean difference [MD] −0.54, 95% confidence interval [CI] −0.95 to −0.19, I2=39%; SOE: moderate) and overall function (6 RCTs, N=616, 0 to 10 scale, MD −0.42, 95% CI −0.73 to −0.16, I2=32%). There was no effect on study withdrawals due to adverse events. There was a large increased risk of dizziness and sedation, and a moderate increased risk of nausea (dizziness: 6 RCTs, N=866, 31.0% vs. 8.0%, relative risk [RR] 3.57, 95% CI 2.42 to 5.60, I2=0%; sedation: 6 RCTs, N=866, 8.0% vs. 1.2%, RR 5.04, 95% CI 2.10 to 11.89, I2=0%; and nausea: 6 RCTs, N=866, 13% vs. 7.5%, RR 1.79, 95% CI 1.19 to 2.77, I2=0%). Synthetic products with high-THC to CBD ratios were associated with a moderate improvement in pain severity, a moderate increase in sedation, and a large increase in nausea (pain: 6 RCTs, N=390, 0 to 10 scale, MD −1.15, 95% CI −1.99 to −0.54, I2=48%; sedation: 3 RCTs, N=335, 19% vs. 10%, RR 1.73, 95% CI 1.03 to 4.63, I2=28%; nausea: 2 RCTs, N=302, 12.3% vs. 6.1%, RR 2.19, 95% CI 0.77 to 5.39; I²=0%). We also found moderate SOE for a large increased risk of dizziness (2 RCTs, 32% vs. 11%, RR 2.74, 95% CI 1.47 to 6.86, I2=40%). Extracted whole-plant products with high-THC to CBD ratios (oral) were associated with a large increased risk of study withdrawal due to adverse events (1 RCT, 13.9% vs. 5.7%, RR 3.12, 95% CI 1.54 to 6.33) and dizziness (1 RCT, 62.2% vs. 7.5%, RR 8.34, 95% CI 4.53 to 15.34); outcomes assessing benefit were not reported or insufficient. We observed a moderate improvement in pain severity when combining all studies of high-THC to CBD ratio (8 RCTs, N=684, MD −1.25, 95% CI −2.09 to −0.71, I2=58%; SOE: moderate). Evidence (including observational studies) on whole-plant cannabis, topical or oral CBD, low-THC to CBD, other cannabinoids, comparisons with active products or between cannabis-related products, and impact on use of opioids was insufficient to draw conclusions. Other important harms (psychosis, cannabis use disorder, and cognitive effects) were not reported. Conclusions. Low to moderate strength evidence suggests small to moderate improvements in pain (mostly neuropathic), and moderate to large increases in common adverse events (dizziness, sedation, nausea) with high and comparable THC to CBD ratio extracted cannabinoids and synthetic products during short-term treatment (1 to 6 months); high-THC to CBD ratio products were also associated with increased risk of withdrawal due to adverse events. Evidence for whole-plant cannabis and other comparisons, outcomes, and plant-based compounds was unavailable or insufficient to draw conclusions. Small sample sizes, lack of evidence for moderate and long-term use and other key outcomes, such as other adverse events and impact on use of opioids during treatment, indicate that more research is needed.

APA, Harvard, Vancouver, ISO, and other styles

McDonagh, Marian S., Jesse Wagner, Azrah Y. Ahmed, Rongwei Fu, Benjamin Morasco, Devan Kansagara, and Roger Chou. Living Systematic Review on Cannabis and Other Plant-Based Treatments for Chronic Pain. Agency for Healthcare Research and Quality (AHRQ), October 2021. http://dx.doi.org/10.23970/ahrqepccer250.

Full text

Abstract:

Objectives. To evaluate the evidence on benefits and harms of cannabinoids and similar plant-based compounds to treat chronic pain. Data sources. Ovid® MEDLINE®, PsycINFO®, Embase®, the Cochrane Library, and SCOPUS® databases, reference lists of included studies, submissions received after Federal Register request were searched to July 2021. Review methods. Using dual review, we screened search results for randomized controlled trials (RCTs) and observational studies of patients with chronic pain evaluating cannabis, kratom, and similar compounds with any comparison group and at least 1 month of treatment or followup. Dual review was used to abstract study data, assess study-level risk of bias, and rate the strength of evidence. Prioritized outcomes included pain, overall function, and adverse events. We grouped studies that assessed tetrahydrocannabinol (THC) and/or cannabidiol (CBD) based on their THC to CBD ratio and categorized them as high-THC to CBD ratio, comparable THC to CBD ratio, and low-THC to CBD ratio. We also grouped studies by whether the product was a whole-plant product (cannabis), cannabinoids extracted or purified from a whole plant, or synthetic. We conducted meta-analyses using the profile likelihood random effects model and assessed between-study heterogeneity using Cochran’s Q statistic chi square and the I2 test for inconsistency. Magnitude of benefit was categorized into no effect or small, moderate, and large effects. Results. From 2,850 abstracts, 20 RCTs (N=1,776) and 7 observational studies (N=13,095) assessing different cannabinoids were included; none of kratom. Studies were primarily short term, and 75 percent enrolled patients with a variety of neuropathic pain. Comparators were primarily placebo or usual care. The strength of evidence (SOE) was low, unless otherwise noted. Compared with placebo, comparable THC to CBD ratio oral spray was associated with a small benefit in change in pain severity (7 RCTs, N=632, 0 to10 scale, mean difference [MD] −0.54, 95% confidence interval [CI] −0.95 to −0.19, I2=28%; SOE: moderate) and overall function (6 RCTs, N=616, 0 to 10 scale, MD −0.42, 95% CI −0.73 to −0.16, I2=24%). There was no effect on study withdrawals due to adverse events. There was a large increased risk of dizziness and sedation and a moderate increased risk of nausea (dizziness: 6 RCTs, N=866, 30% vs. 8%, relative risk [RR] 3.57, 95% CI 2.42 to 5.60, I2=0%; sedation: 6 RCTs, N=866, 22% vs. 16%, RR 5.04, 95% CI 2.10 to 11.89, I2=0%; and nausea: 6 RCTs, N=866, 13% vs. 7.5%, RR 1.79, 95% CI 1.20 to 2.78, I2=0%). Synthetic products with high-THC to CBD ratios were associated with a moderate improvement in pain severity, a moderate increase in sedation, and a large increase in nausea (pain: 6 RCTs, N=390 to 10 scale, MD −1.15, 95% CI −1.99 to −0.54, I2=39%; sedation: 3 RCTs, N=335, 19% vs. 10%, RR 1.73, 95% CI 1.03 to 4.63, I2=0%; nausea: 2 RCTs, N=302, 12% vs. 6%, RR 2.19, 95% CI 0.77 to 5.39; I²=0%). We found moderate SOE for a large increased risk of dizziness (2 RCTs, 32% vs. 11%, RR 2.74, 95% CI 1.47 to 6.86, I2=0%). Extracted whole-plant products with high-THC to CBD ratios (oral) were associated with a large increased risk of study withdrawal due to adverse events (1 RCT, 13.9% vs. 5.7%, RR 3.12, 95% CI 1.54 to 6.33) and dizziness (1 RCT, 62.2% vs. 7.5%, RR 8.34, 95% CI 4.53 to 15.34). We observed a moderate improvement in pain severity when combining all studies of high-THC to CBD ratio (8 RCTs, N=684, MD −1.25, 95% CI −2.09 to −0.71, I2=50%; SOE: moderate). Evidence on whole-plant cannabis, topical CBD, low-THC to CBD, other cannabinoids, comparisons with active products, and impact on use of opioids was insufficient to draw conclusions. Other important harms (psychosis, cannabis use disorder, and cognitive effects) were not reported. Conclusions. Low to moderate strength evidence suggests small to moderate improvements in pain (mostly neuropathic), and moderate to large increases in common adverse events (dizziness, sedation, nausea) and study withdrawal due to adverse events with high- and comparable THC to CBD ratio extracted cannabinoids and synthetic products in short-term treatment (1 to 6 months). Evidence for whole-plant cannabis, and other comparisons, outcomes, and PBCs were unavailable or insufficient to draw conclusions. Small sample sizes, lack of evidence for moderate and long-term use and other key outcomes, such as other adverse events and impact on use of opioids during treatment, indicate that more research is needed.

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!

Contents

Academic literature on the topic '624.151 32'

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Journal articles on the topic "624.151 32"

Book chapters on the topic "624.151 32"

Conference papers on the topic "624.151 32"

Reports on the topic "624.151 32"