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1

Oztas, M., M. Bektaş, I. Karacan, et al. "AB1082 FREQUENCY AND SEVERITY OF COVID-19 IN PATIENTS WITH VARIOUS RHEUMATIC DISEASES TREATED REGULARLY WITH COLCHICINE OR HYDROXYCHLOROQUINE." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 1660.2–1661. http://dx.doi.org/10.1136/annrheumdis-2022-eular.83.

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BackgroundSeveral anti-inflammatory drugs which were targeted different mechanisms and investigated for both prevention and treatment for COVID-19.ObjectivesThe current study aimed to investigate whether patients regularly using colchicine or hydroxychloroquine (HCQ) have an advantage of protection from COVID-19 or developing less severe disease.MethodsPatients who were taking colchicine or HCQ regularly for a rheumatic disease including Familial Mediterranean Fever, Behçet’s syndrome, Systemic Lupus Erythematosus, Rheumatoid Arthritis and Sjogren’s syndrome as well as their healthy household
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2

Avesani, Martina, Alvise Guariento, Chiara Anna Schiena, et al. "138 Pulmonary valve preservation and transannular patch techniques in children with repaired tetralogy of Fallot; echocardiographic comparison." European Heart Journal Supplements 22, Supplement_N (2020): N45—N51. http://dx.doi.org/10.1093/eurheartj/suaa196.

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Abstract Aims To investigate pulmonary valve (PV) and right ventricular function by echocardiography in paediatric patients with repaired Tetralogy of Fallot (ToF), comparing PV preservation surgical strategies to standard transannular patch (TAP) repair. Methods and results All patients undergoing transatrial-transpulmonary repair for ToF at our institution between January 2007 and May 2020 were reviewed retrospectively. Patients were divided into 2 groups, according to the different techniques used (PV preservation strategy vs TAP repair). All patients underwent standard echo-Doppler study i
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3

Deodhar, A., D. Van der Heijde, L. S. Gensler, et al. "POS0939 BIMEKIZUMAB IN PATIENTS WITH ACTIVE NON-RADIOGRAPHIC AXIAL SPONDYLOARTHRITIS: 24-WEEK EFFICACY & SAFETY FROM BE MOBILE 1, A PHASE 3, MULTICENTRE, RANDOMISED, PLACEBO‑CONTROLLED STUDY." Annals of the Rheumatic Diseases 81, Suppl 1 (2022): 772–73. http://dx.doi.org/10.1136/annrheumdis-2022-eular.2416.

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BackgroundBimekizumab (BKZ) is a monoclonal IgG1 antibody that selectively inhibits IL-17F in addition to IL-17A. BKZ has shown rapid and sustained efficacy and was well tolerated up to 156 weeks (wks) in a phase 2b study in patients (pts) with active ankylosing spondylitis.1,2ObjectivesTo assess efficacy and safety of BKZ vs placebo (PBO) in pts with active non-radiographic axial spondyloarthritis (nr-axSpA) up to Wk 24 in the ongoing pivotal phase 3 study, BE MOBILE 1.MethodsBE MOBILE 1 (NCT03928704) comprises a 16-wk double-blind, PBO-controlled period and 36-wk maintenance period. Pts were
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Regierer, A., A. Weiß, M. Bohl-Buehler, et al. "OP0225 DEPRESSIVE SYMPTOMS IN PSA: A CROSS-SECTIONAL ANALYSIS FROM THE NATIONAL GERMAN RABBIT-SPA REGISTRY." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 135.2–136. http://dx.doi.org/10.1136/annrheumdis-2021-eular.2130.

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Background:Psoriatic arthritis (PsA) is a chronic inflammatory disease affecting the musculoskeletal system as well as skin and nails. The prevalence of depression in psoriasis and PsA is high and ranges from 7-40% [1]. Persistent depressive mood may influence disease activity outcome in PsA, especially patient-reported outcomes.Objectives:To assess the correlation of depressive symptoms with PsA-specific outcome parameters.Methods:RABBIT-SpA is a prospective longitudinal cohort study including PsA patients enrolled at start of a new conventional treatment or b/tsDMARD treatment. In regularly
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Fahey, Margaret C., Marion E. Hare, Gerald W. Talcott, et al. "Characteristics Associated With Participation in a Behavioral Weight Loss Randomized Control Trial in the U.S. Military." Military Medicine 184, no. 3-4 (2018): e120-e126. http://dx.doi.org/10.1093/milmed/usy199.

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Abstract Introduction Effective recruitment and subsequent enrollment of diverse populations is often a challenge in randomized controlled trials, especially those focused on weight loss. In the civilian literature, individuals identified as racial and ethnic minorities, men, and younger and older adults are poorly represented in weight loss interventions. There are limited weight loss trials within military populations, and to our knowledge, none reported participant characteristics associated with enrollment. There may be unique motives and barriers for active duty personnel for enrollment i
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Fitria Budi Utami. "The Implementation of Eating Healthy Program in Early Childhood." JPUD - Jurnal Pendidikan Usia Dini 14, no. 1 (2020): 125–40. http://dx.doi.org/10.21009/141.09.

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 Eating habits develop during the first years of a child's life, children learn what, when, and how much to eat through direct experience with food and by observing the eating habits of others. The aim of this study is to get a clear picture of the Eating program Healthy, starting from the planning, implementation, supervision, and evaluation as a case study of nutrition education; to get information about the advantages, disadvantages and effects of implementing a healthy eating program for children. This research was conducted through a case study with qualitative data an
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Mohamed, Fawzy, El Naggar Ayman, Kazamel Gada, and Fawzy Mohamed. "Comparative study between thrombolytic therapy and surgery in 30 cases of acute left sided prosthetic valve thrombosis." Biolife 5, no. 3 (2022): 361–69. https://doi.org/10.5281/zenodo.7371013.

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<strong>ABSTRACT</strong> <strong>Introduction:</strong> Prosthetic valve thrombosis is a potentially life-threatening complication associated with high morbidity and mortality. Transthorasic and transoesophageal echocardiography play an important role to the diagnosis and provides incremental information about the optimal treatment strategy. Guidelines differ on whether surgical treatment or fibrinolysis should be the treatment of choice for the management of left-sided prosthetic valve thrombosis. The aim of the study is to compare between thrombolytic therapy and surgery regarding success,
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Warmansyah, Jhoni, Elis Komalasari, Eliza Febriani, Gusmiati, and Amalina. "Factors Affecting Teacher Readiness for Online Learning (TROL) in Early Childhood Education: TISE and TPACK." JPUD - Jurnal Pendidikan Usia Dini 16, no. 1 (2022): 32–51. http://dx.doi.org/10.21009/jpud.161.03.

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This study aims to find empirical information about the effect of Technological Pedagogical Content Knowledge (TPACK), and Technology Integration Self Efficacy (TISE) on Teacher Readiness for Online Learning (TROL). This study uses a quantitative survey method with path analysis techniques. This study measures the readiness of kindergarten teachers in distance learning in Tanah Datar Regency, West Sumatra Province, Indonesia with a sampling technique using simple random sampling involving 105 teachers. Empirical findings reveal that; 1) there is a direct positive effect of Technology Integrati
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Warmansyah, Jhoni, Restu Yuningsih, Evi Selva Nirwana, et al. "The Effect of Mathematics Learning Approaches and Self-Regulation to Recognize the Concept of Early Numbers Ability." JPUD - Jurnal Pendidikan Usia Dini 17, no. 1 (2023): 54–81. http://dx.doi.org/10.21009/jpud.171.05.

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The ability to recognize the concept of early numbers in early childhood is very important to develop so that children are ready to take part in learning mathematics at a higher level. This study aims to determine the effect of mathematics learning approaches and self-regulation to recognize the concept of early numbers ability in kindergarten. The study used an experimental method with a treatment design by level 2x2. The sample used was 32 children. Score data, ability to recognize number concepts, analyzed and interpreted. The results showed that: (1) The Realistic Mathematics Education app
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Guariento, Alvise, Martina Avesani, Chiara A. Schiena, et al. "Abstract 15118: Pulmonary Valve Preservation During Tetralogy of Fallot Repair is Associated With Enhanced Pulmonary Valve and Right Ventricular Function." Circulation 142, Suppl_3 (2020). http://dx.doi.org/10.1161/circ.142.suppl_3.15118.

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Introduction: Many centers have recently adopted pulmonary valve (PV) preservation procedures to prevent the detrimental long-term effects of chronic pulmonary regurgitation after tetralogy of Fallot (ToF) repair. Hypothesis: Here, we investigated PV and right ventricular function after PV preservation surgical strategies compared to standard transannular patch (TAP) repair. Methods: All patients undergoing transatrial-transpulmonary repair for ToF with PV stenosis at our institution between January 2007 and May 2020 were reviewed retrospectively. Patients were divided into 2 main groups, acco
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Coccolini, Federico, Alessio Mazzoni, Camilla Cremonini, et al. "Colorectal neoplastic emergencies in immunocompromised patients: preliminary result from the Web-based International Register of Emergency Surgery and Trauma (WIRES-T trial)." Updates in Surgery, May 9, 2023. http://dx.doi.org/10.1007/s13304-023-01521-8.

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AbstractAssociation of advanced age, neoplastic disease and immunocompromission (IC) may lead to surgical emergencies. Few data exist about this topic. Present study reports the preliminary data from the WIRES-T trial about patients managed for colorectal neoplastic emergencies in immunocompromised patients. The required data were taken from a prospective observational international register. The study was approved by the Ethical Committee with approval n. 17575; ClinicalTrials.gov Identifier: NCT03643718. 839 patients were collected; 753 (80.7%) with mild–moderate IC and 86 (10.3%) with sever
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Matus Gonzalez, Andrea, Nicole Evangelidis, Martin Howell, et al. "Outcomes for clinical trials involving adults with chronic kidney disease: a multinational Delphi survey involving patients, caregivers, and health professionals." Nephrology Dialysis Transplantation, January 17, 2024. http://dx.doi.org/10.1093/ndt/gfae010.

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Abstract Background Many outcomes of high priority to patients and clinicians are infrequently and inconsistently reported across trials in CKD, which generates research waste and limits evidence-informed decision making. We aimed to generate consensus among patients/caregivers and health professionals on critically important outcomes for trials in CKD prior to kidney failure and the need for kidney replacement therapy, and to describe the reasons for their choices. Methods Online two-round international Delphi survey. Adult patients with CKD (all stages and diagnoses), caregivers and health p
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13

Avesani, M., A. Guariento, CA Schiena, et al. "Echocardiographic comparison between pulmonary valve preservation and transannular patch techniques in children with repaired Tetralogy of Fallot." European Heart Journal - Cardiovascular Imaging 22, Supplement_1 (2021). http://dx.doi.org/10.1093/ehjci/jeaa356.415.

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Abstract Funding Acknowledgements Type of funding sources: None. INTRODUCTION Many centers have recently adopted pulmonary valve (PV) preservation procedures to prevent the detrimental long-term effects of chronic pulmonary regurgitation after tetralogy of Fallot (ToF) repair. PURPOSE The aim of our study was to investigate pulmonary valve (PV) and right ventricular function by echocardiography in paediatric patients with repaired Tetralogy of Fallot (ToF), comparing PV preservation surgical strategies to standard transannular patch (TAP) repair. METHODS All patients undergoing transatrial-tra
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14

sprotocols. "A highly-sensitive multisubstrate-compatible chemiluminescent immunoassay for human fetuin A." January 6, 2015. https://doi.org/10.5281/zenodo.13763.

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Authors: Sandeep Kumar Vashist ### Abstract We report a highly-sensitive chemiluminescent immunoassay (CIA) for the detection of human fetuin A (HFA), which is based on the leach-proof covalent crosslinking of anti-HFA capture antibodies on 3-aminopropyltriethoxysilane (APTES)-functionalized 96-well chemiluminescent microtiter plates (CMTP) using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride and N-hydroxysulfosuccinimide. It has more than 3-fold reduced overall assay duration than the commercial enzyme-linked immunosorbent assay (ELISA). Moreover, it has a wide detection range i
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Hong Son, Bui, Vu Van Nga, Le Thi Diem Hong, and Do Thi Quynh. "Potent Natural Inhibitors of Alpha-Glucosidase and the Application of Aspergillus spp. in Diabetes type 2 Drugs: a Review." VNU Journal of Science: Medical and Pharmaceutical Sciences 38, no. 1 (2022). http://dx.doi.org/10.25073/2588-1132/vnumps.4334.

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Diabetes Mellitus has been becoming a disease of the century, and disease incidence is still rising worldwide. It causes many serious complications, especially in the eye, heart, kidneys, brain, and vascular system, such as diabetic nephropathy, diabetic retinopathy, liver fa­ilure, etc. Moreover, the process of controlling this disease is complicated. Meanwhile, the antidiabetic drugs on the market are facing some problems with a wide range of adverse reactions. Therefore, finding new drugs to treat diabetes has always been a topic that many researchers are interested in, especially drugs der
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Minh, Phan Hong, Vu Khanh Linh, Nguyen Thanh Hai, and Bui Thanh Tung. "A Comprehensive Review of Vaccines against Covid-19." VNU Journal of Science: Medical and Pharmaceutical Sciences 37, no. 3 (2021). http://dx.doi.org/10.25073/2588-1132/vnumps.4365.

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The globe is engulfed by one of the most extensive public health crises as COVID-19 has become a leading cause of death worldwide. COVID-19 was first detected in Wuhan, China, in December 2019, causing the severe acute respiratory syndrome. This review discusses issues related to Covid-19 vaccines, such as vaccine development targets, vaccine types, efficacy, limitations and development prospects.&#x0D; Keywords: Covid-19, SARS-CoV-2, vaccine, spike protein.&#x0D; References&#x0D; [1] C. Wang, P. W. Horby, F. G. Hayden, G. F. Gao, A Novel Coronavirus Outbreak of Global Health Concern, The Lanc
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Dolomatov, S.I., та W. Zukow. "Эпигенетика почек = Kidneys epigenetics". 7 липня 2019. https://doi.org/10.5281/zenodo.3270754.

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<strong>Dolomatov S.I., Zukow W. </strong><strong>Эпигенетика почек</strong><strong> = Kidney</strong><strong>s</strong><strong> epigenetics</strong><strong>. </strong><strong>RSW. Radom,</strong><strong> 144 </strong><strong>p. ISBN </strong><strong>9780359774524</strong><strong>.</strong><strong> DOI </strong><strong>http://dx.doi.org/10.5281/zenodo.3270699</strong><strong> PBN Poland </strong><strong>https://pbn.nauka.gov.pl/sedno-webapp/works/917606</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; <strong>Radomska Szkoła Wyższa w Radomiu, Radom, Poland</strong> &nbsp; &nbsp; &nbsp; &nbsp; &nbsp
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Kojo, Kosuke, Tomoko Oguri, Takazo Tanaka, et al. "Seminal plasma metallomics: a new horizon for diagnosing and managing male infertility." Revista Internacional de Andrología 23, Published Ahead of Print (2025). https://doi.org/10.22514/j.androl.2025.013.

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The authors, Kosuke Kojo and Tomoko Oguri, contributed equally. This HTML edition is publicly accessible at the following URL:https://academic298uro.github.io/open-archive/2025/seminal-plasma-metallomics-new-horizon/ Abstract Seminal plasma contains a wide range of biomolecules&mdash;including inorganic elements&mdash;that may significantly influence male reproductive function. Historically, semen analysis has focused on sperm count and motility, while overlooking the diagnostic potential of this acellular fraction. This narrative review synthesizes historical perspectives on seminal plasma me
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Sarkar, Jagannath. "Genomics of Brevibacterium strains reveal adaptations necessary to acclimatize in different marine environments." June 7, 2024. https://doi.org/10.5281/zenodo.13624149.

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<strong>ABSTRACT</strong> Microbes are ubiquitous throughout the seawater and underlying sediment, which covers the vast region of the earth surface. Strains of different genera under the phylum <em>Actinobacteria</em> are ubiquitous all-over different environments of the earth surfaces. A well-studied aerobic genus, <em>Brevibacterium</em>, under the phylum also found to be omnipresent in both marine and terrestrial environments, ranging from coastal to open ocean. Which raise question, whether marine strains are phylogenetically distinct from others or not, and what are the special genomic a
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