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Journal articles on the topic '646.7 /6'

Author: Grafiati

Published: 27 July 2024

Last updated: 31 July 2025

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1

Bosworth, C. Edmund. "Arab Attacks on Rhodes in the Pre-Ottoman Period." Journal of the Royal Asiatic Society 6, no. 2 (1996): 157–64. http://dx.doi.org/10.1017/s1356186300007161.

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The period of Mu'āwiya b. Sufyān, as governor over Syria and al-Jazīra under the caliph 'Uthmān from at least 25–6/646–7, and then as Umayyad caliph in Damascus 41–60/661–80, was crucial for the first impetus of Arab expansion in the eastern Mediterranean. Egypt had been conquered by 'Amr b. al-'Āṣ during 'Umar's caliphate, and the great port of Alexandria passed definitively into Arab hands by 21/642. Alexandria possessed famed dockyards, and had a Greco-Egyptian population which the Arabs were able to press into service for manning their warships operating out of the Egyptian ports and out o

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Grangeiro, Leilson Costa, Josué Fernandes Pedrosa, Francisco Bezerra Neto, and Maria Z. de Negreiros. "Rendimento de híbridos de melão amarelo em diferentes densidades de plantio." Horticultura Brasileira 17, no. 3 (1999): 200–206. http://dx.doi.org/10.1590/s0102-05361999000300005.

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Este trabalho teve como objetivo avaliar o rendimento de híbridos de melão amarelo em diferentes densidades de plantio. Para tanto, conduziu-se um experimento na Fazenda Santa Júlia Agro Comercial Exportadora de Frutas Tropicais Ltda., no município de Mossoró - RN. O delineamento experimental foi o de blocos casualizados em esquema fatorial 3 x 4, com quatro repetições, sendo o primeiro fator, os híbridos (Gold Mine, AF 646 e XPH 13096) e o segundo as densidades de plantio (10.000, 20.000, 30.000 e 40.000 plantas/ha). As características avaliadas foram, número de frutos por planta e total, pes

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3

Hadiantika, Reza Adinda, Robby Hidajat, and Tutut Pristiati. "Tari Remo Putri pada Ludruk Lerok Anyar Karya Marsam Hidayat." JoLLA: Journal of Language, Literature, and Arts 3, no. 5 (2023): 630–46. http://dx.doi.org/10.17977/um064v3i52023p630-646.

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Penelitian ini mengkaji tentang Tari Remo Putri yang membuka pertunjukan Ludruk Lerok Anyar. Tari Remo Putri karya Marsam ini memiliki karakter dan keunikan melalui gerak tarinya. Akan tetapi, sangat banyak penonton yang tidak mengetahui hal tersebut sehingga tari ini kurang mendapatkan apresiasi dari masyarakat. Tujuan penelitian ini adalah untuk mendeskripsikan struktur koreografi Tari Remo Putri pada Ludruk Lerok Anyar karya Marsam Hidayat. Metode penelitian yang digunakan adalah metode kualitatif dengan teknik pengumpulan data menggunakan teknik observasi, wawan-cara, dan dokumentasi. Data

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Komrokji, Rami S., Amy E. DeZern, Katrina Zell, et al. "Validation of International Working Group (IWG) Response Criteria in Higher-Risk Myelodysplastic Syndromes (MDS): A Report on Behalf of the MDS Clinical Research Consortium (MDS CRC)." Blood 126, no. 23 (2015): 909. http://dx.doi.org/10.1182/blood.v126.23.909.909.

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Introduction The primary goal for treatment of higher-risk MDS patients (pts) is to improve overall survival (OS) and delay acute myeloid leukemia (AML) evolution. The IWG 2006 response criteria are used in clinical trials and in clinical practice for assessing efficacy of MDS therapies. These criteria were originally proposed by an international group of experts based on available data and consensus. In an ad hoc landmark analysis of the AZA-001 study using the 2006 IWG criteria, pts who achieved hematological improvement (HI), complete response (CR), marrow CR (mCR), or partial response (PR)

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KESLER, SHELLI R., RAMONA O. HOPKINS, LINDELL K. WEAVER, DUANE D. BLATTER, HOLLY EDGE-BOOTH, and ERIN D. BIGLER. "Verbal memory deficits associated with fornix atrophy in carbon monoxide poisoning." Journal of the International Neuropsychological Society 7, no. 5 (2001): 640–46. http://dx.doi.org/10.1017/s1355617701005112.

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Magnetic resonance (MR) images and neuropsychological testing data of 69 carbon monoxide (CO) poisoned patients were prospectively obtained within 1 day of CO poisoning, two weeks and six months. CO patients' Day 1 cross-sectional fornix surface area measurements, corrected for head size by using a fornix-to-brain ratio (FBR), were compared to normal age and gender-matched controls. Additionally, a within-subjects analysis was performed comparing the mean areas between CO patients' Day 1, 2 weeks and 6-month FBR. The FBR was correlated with patients' neuropsychological data. There were no sign

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Granerod, J., NS Crowcroft, DW Brown, and T. Solomon. "Testing for urinary infection using urinary reagent test strips in unselected acute medical patients." Clinical Medicine 7, no. 6 (2007): 646–47. http://dx.doi.org/10.7861/clinmedicine.7-6-646.

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YAMASAKI, HIROSHI, HIROSHI KAJIHARA, and SHUNSUKE F. MAWATARI. "First report of kinorhynchs from Hokkaido, Japan, including a new species of Pycnophyes (Pycnophyidae: Homalorhagida)." Zootaxa 3425, no. 1 (2012): 23. http://dx.doi.org/10.11646/zootaxa.3425.1.2.

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We describe and illustrate Pycnophyes oshoroensis sp. nov. from Hokkaido, northern Japan. This species is characterized by (1)a trunk 646–775μm long, and a presence of (2) middorsal elevation on segments 2–9, (3) anterior middorsal projection onsegment 2, (4) even anterior tergal margin of segment 1, (5) reticulate cuticular area on anterior margin of tergal, episternal, andmidsternal plates of segment 1, (6) laterodorsal setae on segments 2–9, (7) paralateral setae on segments 1, 2, 4, 6, 7, 8 and 10,(8) ventrolateral setae on segments 1, 5 and 10, (9) ventromedial setae on segments 3–9, and

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8

Dunbar-Hall, P. "Veronica Crowe, (Ed.), Traditional Music of Japan, No 6 of Australia's Multicultural Music. Accompanying cassette. 1992; 88 pp., ISBN 0 646 07874 7." International Journal of Music Education 20, no. 1 (1992): 83–84. http://dx.doi.org/10.1177/025576149202000121.

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9

Suprapti. "PEMBERIAN BISKUIT DARI BAHAN TEPUNG TEMPE UNTUK MENURUNKAN ANGKA KEJADIAN DIARE PADA BALITA." Journal of Scientech Research and Development 1, no. 1 (2019): 044–51. http://dx.doi.org/10.56670/jsrd.v1i1.6.

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Diare masih menjadi salah satu masalah kesehatan masyarakat yang utama di negara berkembang seperti di Indonesia. Pada 2013, di Indonesia terjadi wabah yang tersebar di 6 provinsi, 8 kabupaten dengan total 646 orang dengan 7 kematian (Case Fatality Rate/CFR = 1,08%). Berdasarkan Dinas Kesehatan Kabupaten Gresik kejadian diare pada semua umur di Kecamatan Gresik cukup tinggi berada diperingkat kedua dari 17 Kecamatan yaitu mempunyai jumlah kejadian sebanyak 5956 kasus. Penelitian ini bertujuan untuk mengetahui efektifitas pemberian biskuit dari tepung tempe pada balita yang menderita diare. Met

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Agarwal, Neeraj, Sumanta K. Pal, Richard C. Lauer, et al. "Results of a phase II study to evaluate the safety and efficacy of RX-0201 in combination with everolimus in subjects with metastatic renal cell carcinoma (mRCC)." Journal of Clinical Oncology 37, no. 7_suppl (2019): 646. http://dx.doi.org/10.1200/jco.2019.37.7_suppl.646.

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646 Background: RX-0201 is a novel 20-mer oligonucleotide that binds to mRNA coding for AKT-1, preventing AKT-1 expression and limiting the amount of downstream p-AKT. In vitro RX-0201, in combination with everolimus, additively inhibited Caki-1 cell growth. RX-0201, in combination with everolimus, to treat mRCC was evaluated in a Phase 1b/2 clinical study. Methods: This Phase 1b/2 study (2‐stage design, NCT02089334 ) evaluated the efficacy and safety of RX‐0201 in combination with everolimus in eligible subjects with mRCC. Eligible subjects must have had confirmed histologic or cytologic evid

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Yip, Shea Ping. "Single-tube multiplex PCR-SSCP analysis distinguishes 7 common ABO alleles and readily identifies new alleles." Blood 95, no. 4 (2000): 1487–92. http://dx.doi.org/10.1182/blood.v95.4.1487.004k53_1487_1492.

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The ABO blood group is clinically the most important blood group system. Elucidation of the molecular basis of the ABO polymorphism allows genotype determination without family studies. Described here is a new method based on the simultaneous amplification by polymerase chain reaction (PCR) of 3 fragments from exon 6, and 5′ and 3′ ends of exon 7 of the ABO gene, followed by single-strand conformation polymorphism (SSCP) analysis. This multiplex PCR-SSCP protocol allows the well-established base changes at 9 nucleotide positions 261, 297, 467, 526, 646, 657, 681, 1059, and 1096 to be assayed s

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Newbold, C. J., N. McKain, and R. J. Wallace. "Combined effects ofAspergillus oryzaefermentation extract and monensin on fermentation in the rumen simulation technique (Rusitec)." Journal of Agricultural Science 121, no. 2 (1993): 241–46. http://dx.doi.org/10.1017/s002185960007711x.

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SUMMARYMonensin, an ionophore, andAspergillus oryzaefermentation extract (AO), a fungal feed additive, are growth promoters which modify rumen fermentation. The effects of combining these additives were determined in the rumen simulation technique (Rusitec). Sixteen vessels received 20 g/day of a diet of hay, barley, molasses, fishmeal and a mineral/vitamin mixture (500, 299·5, 100, 91 and 9·5 g/kg DM respectively). AO, monensin (M) and AO + monensin (AO/M) were each added to four vessels at 500, 10 and (500 + 10) mg/day respectively. Both M and AO/M increased propionate (14·5 and 138v.91 mmol

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Thakker, Parth, Connor Drake, Jiping Zeng, Timothy A. Masterson, and Clint Cary. "Circulating tumor DNA as a prognostic biomarker to predict retroperitoneal histology in patients undergoing retroperitoneal lymph node dissection." Journal of Clinical Oncology 43, no. 5_suppl (2025): 646. https://doi.org/10.1200/jco.2025.43.5_suppl.646.

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646 Background: Serum tumor markers (STM) are used in the management of patients with testicular cancer. However, a proportion have normal STM even with cancer present. Circulating tumor DNA (ctDNA) has shown promise in for detection of persistent disease. We sought to determine the utility of ctDNA for predicting retroperitoneal histology by comparing patients’ retroperitoneal lymph node dissection (RPLND) histology with their pre-operative ctDNA status. Methods: Patients undergoing primary (P-RPLND) or post-chemotherapy (PC-RPLND) from March 2023 to January 2024 had prospectively collected p

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Morelli, Maria Pia, Changqing Xie, Gagan Brar, et al. "A phase I/II study of pexa-vec oncolytic virus in combination with immune checkpoint inhibition in refractory colorectal cancer: Safety report." Journal of Clinical Oncology 37, no. 4_suppl (2019): 646. http://dx.doi.org/10.1200/jco.2019.37.4_suppl.646.

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646 Background: The efficacy of immune checkpoint inhibitor has been limited to small portion of colorectal cancer (CRC) patients whose tumors with mismatch repair (MMR) gene abnormalities. There is an urgent need for patients with MMR proficient (pMMR) tumors. Oncolytic immunotherapy represents a novel therapeutic platform for the treatment of cancer with unique activity compared to conventional chemotherapy. The trial is to evaluate if the combination of Pexa-Vec oncolytic virus (PV) with immune checkpoint inhibition enhance antitumor immunity. Methods: Patients with microsatellite-stable an

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Ducas, Robin Alexandra, David A. Javier, Rohan D’Souza, Candice K. Silversides, and Wendy Tsang. "Pregnancy outcomes in women with significant valve disease: a systematic review and meta-analysis." Heart 106, no. 7 (2020): 512–19. http://dx.doi.org/10.1136/heartjnl-2019-315859.

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ObjectiveTo perform a systematic review and meta-analysis of maternal/fetal outcomes in pregnant women with moderate/severe native valvular heart disease (VHD) from medium/higher Human Development Index (HDI) countries.MethodsOvidSP platform databases were searched (1985-January 2019) to identify studies reporting pregnancy outcomes in women with moderate/severe VHD. The primary maternal outcome was maternal mortality. The primary fetal/neonatal outcome was stillbirth and neonatal death. Pooled incidences and 95% confidence intervals (CI) of maternal/fetal outcomes could only be calculated fro

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Editorial2, Departamento. "Correction to the article “Profiles on Adolescent Internet Addiction: A Taxonomy with Latent Profiling Analysis”, Published on Acta Med Port 2022 Sep;35(9):644-651." Acta Médica Portuguesa 35, no. 9 (2022): 703. http://dx.doi.org/10.20344/amp.18862.

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On page 646, Section ‘RESULTS’,On paragraph ‘Model estimation and selection’,Line 3, where it reads (in red):Firstly, we examined fit statistics (Table 5), namely the Akaike Information criterion (AIC) (...)It should read (in blue):Firstly, we examined fit statistics (Table 3), namely the Akaike Information criterion (AIC) (...)Line 9, where it reads (in red):(...) (LRT = 57.33, p < 0.0001, see Table 5) (...)It should read (in blue):(...) (LRT = 57.33, p < 0.0001, see Table 3) (...)On paragraph ‘Classification accuracy of the model’,Line 1, where it reads (in red):The probabilities of co

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Predieri, S., D. T. Krizek, R. M. Mirecki, H. A. Norman, and R. H. Zimmerman. "646 (PS 4) PHOTOSYNTHETIC PHOTON FLUX AND UV-B EFFECTS ON ETHYLENE EVOLUTION, PROLIFERATION, AND LIPID CONTENT OF `DOYENNE D'HIVER' PEAR IN VITRO." HortScience 28, no. 5 (1993): 543g—544. http://dx.doi.org/10.21273/hortsci.28.5.543g.

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In vitro-grown shoots of `Doyenne d'Hiver' pear (Pyrus communis L.) were maintained for 7 days on 16-h photoperiods at photosynthetic photon fluxes (PPF) of 90, 180 or 270 μmol·m-2·s-1 and irradiated 6 h per day midway through the photoperiod at 0.2 (-UV-B) or 12.0 (+UV-B) kJ·m-2·d-1 of biologically effective ultraviolet-B (UV-BBE) radiation. Increased ethylene production from UV-BBE-treated shoots as compared to the control was recorded after 24 h in cultures grown under 90 and 180 μmol·m-2·s-1 and after 72 h in shoots grown under 270 μmol·m-2·s-1; PPF level had little effect on amount of eth

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Ma, Barbara, Abhinav Jaiswal, K. Sanjana Devi, et al. "646 Evaluating a preclinical model of contact hypersensitivity for skin immune checkpoint toxicity." Journal for ImmunoTherapy of Cancer 8, Suppl 3 (2020): A683. http://dx.doi.org/10.1136/jitc-2020-sitc2020.0646.

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BackgroundImmune checkpoint inhibitors (ICIs) are limited by the high incidence of immune-related adverse events (irAEs) occurring in up to 40% of solid tumor patients on anti-PD-1 monotherapy 1 2 and 72% in anti-CTLA-4/anti-PD-1 combination.3 4 These toxicities can cause treatment cessation, hospitalization and even death.5–7 IrAEs are variable in severity, timing, onset, and remain poorly understood. Amongst the different toxicities, skin irAEs are most frequent, occur the earliest, and are correlated with a positive prognosis.4 8 However, there is a lack of preclinical models to study check

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Singh, V., J. Krishnamurthy, O. Frankfurt, et al. "The Effect of Increasing CD34+ Cell Doses on Time to Engraftment after Autotransplantation for Hematologic Malignancies." Blood 112, no. 11 (2008): 1115. http://dx.doi.org/10.1182/blood.v112.11.1115.1115.

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Abstract It is thought that 2 x 106/kg is the minimum CD34+ cell dose needed for autotransplantation, while the ideal dose is generally accepted to be 5 x 106/kg. Whether infusing cell doses higher than 5 x 106/kg offers additional benefit is unknown. The relationship between time to standard engraftment endpoints (0.5 x 109/L Neutrophils – ANC 0.5, 1 x 109/L neutrophils – ANC 1.0, 20 x 109/L platelets – PLT 20, and 50 x 109/L platelets – PLT 50) and the CD34+ cell doses infused was explored in 754 autografts performed for malignant diseases in adult patients: 32 leukemia, 195 lymphoma, 514 my

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Bhagavathula, Akshaya Srikanth, Kota Vidyasagar, and Wubshet Tesfaye. "Efficacy and Safety of Tirzepatide in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Randomized Phase II/III Trials." Pharmaceuticals 14, no. 10 (2021): 991. http://dx.doi.org/10.3390/ph14100991.

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Tirzepatide is a novel once-a-week dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist, currently under trial to assess glycemic efficacy and safety in people with type 2 diabetes. A systematic review and meta-analysis were conducted to investigate the efficacy of tirzepatide on glycated hemoglobin (HbA1c, %), fasting serum glucose (mg/dL), and body weight (kg) in patients with uncontrolled type 2 diabetes (HbA1c > 7.0%). Mean changes for efficacy and proportions (safety) with corresponding 95% confidence intervals (CIs) were used to provide pooled

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Silveira, Elineide B., Sami J. Michereff, and Rosa L. R. Mariano. "Severidade da mancha-aquosa em meloeiro sob diferentes condições de molhamento foliar e concentração de inóculo de Acidovorax avenae subsp. citrulli." Fitopatologia Brasileira 28, no. 2 (2003): 171–75. http://dx.doi.org/10.1590/s0100-41582003000200009.

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Avaliou-se a severidade da mancha-aquosa em meloeiro (Cucumis melo) em diferentes intervalos de molhamento foliar (0, 6, 12, 24 e 48 h) e do início do período de molhamento foliar (0, 6, 12, 24 e 48 h após inoculação), e diferentes concentrações de inóculo de Acidovorax avenae subsp. citrulli (3,4 x 10¹ a 3,4 x 10(7) UFC.ml-1). Foram utilizados três isolados do patógeno e os híbridos de meloeiro tipo Amarelo, AF-646 e AF-682. As folhas das plantas com 20 dias foram pulverizadas com a suspensão bacteriana e mantidas em casa de vegetação, sendo determinados período de incubação, taxa de progress

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Hashmi, Ahmar H., Nicola Solomon, Sue J. Lee, et al. "Nutrition in transition: historical cohort analysis summarising trends in under- and over-nutrition among pregnant women in a marginalised population along the Thailand–Myanmar border from 1986 to 2016." British Journal of Nutrition 121, no. 12 (2019): 1413–23. http://dx.doi.org/10.1017/s0007114519000758.

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AbstractThe objective of the present study is to summarise trends in under- and over-nutrition in pregnant women on the Thailand–Myanmar border. Refugees contributed data from 1986 to 2016 and migrants from 1999 to 2016 for weight at first antenatal consultation. BMI and gestational weight gain (GWG) data were available during 2004–2016 when height was routinely measured. Risk factors for low and high BMI were analysed for <18·5 kg/m2 or ≥23 kg/m2, respectively. A total of 48 062 pregnancies over 30 years were available for weight analysis and 14 646 pregnancies over 13 years (2004–2016) ha

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Shiozawa, Aki, Shelagh M. Szabo, Anna Bolzani, Antoinette Cheung, and Hyon K. Choi. "Serum Uric Acid and the Risk of Incident and Recurrent Gout: A Systematic Review." Journal of Rheumatology 44, no. 3 (2017): 388–96. http://dx.doi.org/10.3899/jrheum.160452.

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Objective.Lowering serum uric acid (SUA) levels can essentially cure gout; however, this is not widely practiced. To summarize epidemiologic evidence related to this causal link, we conducted a systematic review of the published literature reporting the association between SUA level and incident and recurrent gout (i.e., gout flares).Methods.We systematically searched Medline, EMBASE, and the Cochrane Database of Systematic Reviews using separate search strategies for incident gout and recurrent gout. We screened 646 abstracts to identify 8 eligible articles reporting gout incidence and 913 ab

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Xu, Wei, Yu-Lin Chen, Ying Zhao, Li-Jie Wang, Jiu-Jun Li, and Chun-Feng Liu. "A Clinical Study of Toxication Caused by Carbamazepine Abuse in Adolescents." BioMed Research International 2018 (2018): 1–6. http://dx.doi.org/10.1155/2018/3201203.

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Carbamazepine is known to produce the side effect of euphoria. As such, it lends itself to being a drug of abuse, particularly in the adolescent population. This retrospective study evaluated carbamazepine abuse, treatment course, and associated morbidity in Chinese adolescents. The median dose of carbamazepine resulting in overdose was 2,000 mg (800–5,000). Patients were largely from urban-rural fringe areas (76.47%, 52.94%) with school performance within the last 1/3 range and (52.94%) unsupervised by parents. 35.29% experienced an obvious sense of euphoria. All patients had nervous system s

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Goseberg, Nils, Jacob Stolle, and Ioan Nistor. "MULTIPLE IMPACTS OF DEBRIS ON A VERTICAL OBSTACLE." Coastal Engineering Proceedings, no. 36 (December 30, 2018): 22. http://dx.doi.org/10.9753/icce.v36.structures.22.

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Past tsunami events have caused extreme damage in coastal regions. Examples are the Indian Ocean Tsunami in 2004 and the Tohuku Tsunami in 2011. These extreme natural disasters brought into light the devastating nature which tsunami-induced inundation might inflict when propagating on-land. As a result of eye-witness reports and extensive media coverage, a wealth of evidence showing multi-phase fluid motion entraining a solid phase consisting of entrained debris, ranging from sediment grains to large vessels became available. In this context, debris impacts have been linked to major infrastruc

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Pettersson, E., P. Lichtenstein, H. Larsson, et al. "Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls." Psychological Medicine 49, no. 07 (2018): 1166–73. http://dx.doi.org/10.1017/s0033291718002039.

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AbstractBackgroundMost studies underline the contribution of heritable factors for psychiatric disorders. However, heritability estimates depend on the population under study, diagnostic instruments, and study designs that each has its inherent assumptions, strengths, and biases. We aim to test the homogeneity in heritability estimates between two powerful, and state of the art study designs for eight psychiatric disorders.MethodsWe assessed heritability based on data of Swedish siblings (N = 4 408 646 full and maternal half-siblings), and based on summary data of eight samples with measured g

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Nistor, Ioan, Nils Goseberg, Jacob Stolle, Tomoya Shibayama, and Takahito Mikami. "COASTAL FLOODING-INDUCED DEBRIS MOTION." Coastal Engineering Proceedings, no. 36 (December 30, 2018): 41. http://dx.doi.org/10.9753/icce.v36.currents.41.

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Extreme coastal events such as the 2004 Indian Ocean Tsunami, the 2011 Tohoku Tsunami as well as the 2005 Katrina and 2012 Sandy hurricanes demonstrated that, hydrodynamic loading aside, debris loading represents a major factor in the extreme loading conditions experienced by inland infrastructure. While extreme hydrodynamic loading due to coastal flooding events has been the object of intense research over the past decade, few studies dealing with debris impact due to coastal flooding have been conducted. Post-tsunami forensic engineering field investigations conducted by the authors (Nistor

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BEGGS, EDWIN, JOSÉ FÉLIX COSTA, DIOGO POÇAS, and JOHN V. TUCKER. "Computations with oracles that measure vanishing quantities." Mathematical Structures in Computer Science 27, no. 8 (2016): 1315–63. http://dx.doi.org/10.1017/s0960129516000219.

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We consider computation with real numbers that arise through a process of physical measurement. We have developed a theory in which physical experiments that measure quantities can be used as oracles to algorithms and we have begun to classify the computational power of various forms of experiment using non-uniform complexity classes. Earlier, in Beggs et al. (2014 Reviews of Symbolic Logic7(4) 618–646), we observed that measurement can be viewed as a process of comparing a rational number z – a test quantity – with a real number y – an unknown quantity; each oracle call performs such a compar

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Avelino-Silva, Thiago J., Sei J. Lee, Kenneth E. Covinsky, et al. "External Validation of the Walter Index for Posthospitalization Mortality Prediction in Older Adults." JAMA Network Open 8, no. 1 (2025): e2455475. https://doi.org/10.1001/jamanetworkopen.2024.55475.

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ImportanceThe Walter Index is a widely used prognostic tool for assessing 12-month mortality risk among hospitalized older adults. Developed in the US in 2001, its accuracy in contemporary non-US contexts is unclear.ObjectiveTo evaluate the external validity of the Walter Index in predicting posthospitalization mortality risk in Brazilian older adult inpatients.Design, Setting, and ParticipantsThis prognostic study used data from a cohort of adults aged 70 years or older admitted to the geriatric unit of a university hospital in Brazil from January 1, 2009, to February 28, 2020. Participants u

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Gal, Grégoire Le, Michael Kovacs, Marc Carrier, et al. "Risk of recurrent venous thromboembolism after a first oestrogen-associated episode." Thrombosis and Haemostasis 104, no. 09 (2010): 498–503. http://dx.doi.org/10.1160/th09-10-0685.

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SummaryThe use of exogenous oestrogen in women with otherwise unprovoked venous thromboembolism (VTE) could be considered sufficient explanation to classify VTE as provoked if the risk of recurrent VTE after 3–6 months of anticoagulant treatment is similar to the risk of recurrent VTE observed after a surgery or prolonged immobilisation. Our objective was to assess the risk of recurrent VTE in women after a first unprovoked episode on oestrogen. The REVERSE study is a cohort study of patients with a first unprovoked VTE treated with anticoagulant treatment for 5–7 months. The risk of recurrent

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López-Rivero, José L., Eduardo Agüera, José G. Monterde, Joaquín Vivo, and María V. Rodríguez-Barbudo. "Skeletal muscle fiber size in untrained and endurance-trained horses." American Journal of Veterinary Research 53, no. 5 (1992): 847–50. http://dx.doi.org/10.2460/ajvr.1992.53.05.847.

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Summary The mean area and minimal diameter of 3 histochemically determined myofiber types (1, 2A, and 2B; myosin ATPase in acid buffer) were calculated in middle gluteal muscle biopsy specimens from 62 stallions, 47 Andalusians and 15 Arabians, ranging in age from 6 to 12 years. Fourteen Andalusians and 7 Arabians were untrained, and the remainder were actively endurance-trained. The 6-month training schedules involved walking, slow trotting, and cantering. Fourteen Andalusians were moder-ately endurance-trained, whereas the other 19 Andalusians and 8 Arabians were strongly endurance-trained.

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Ziade, N., S. Al Emadi, M. Abu Jbara, et al. "AB0104 CONCORDANCE BETWEEN THE PHYSICIAN’S AND THE PATIENT’S ASSESSMENT OF DISEASE ACTIVITY IN RHEUMATOID ARTHRITIS: RESULTS OF THE AUTODAS-MEAC STUDY AT ONE YEAR." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1080. http://dx.doi.org/10.1136/annrheumdis-2021-eular.646.

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Background:Involving the patients with rheumatoid arthritis (RA) in the assessment of their disease may increase their adherence to treatment, improve the disease outcomes and facilitate the application of telehealth. We previously reported an excellent concordance between the Disease Activity Score (DAS-28) performed by physicians and patients at the baseline visit of this prospective study (1).Objectives:To evaluate the persistence of the concordance between the physician’ and the patient’s assessment of disease activity in RA using DAS-28 after one year.Methods:At the baseline visit, patien

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Liubchenko, A. I. "Phenological evaluation of the established somaclonal line of camelina sativa resistant to salt and osmotic stress." Collected Works of Uman National University of Horticulture 1, no. 97 (2020): 52–61. http://dx.doi.org/10.31395/2415-8240-2020-97-1-52-61.

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The biological features of сamelina sativa make it possible to grow it in different soil and climatic conditions with high economic efficiency, to obtain environmentally friendly products and make full use of the natural potential of the region. Camelina oil is used for the production of varnishes, paints, soaps, plastics, biodiesel. It is also used for dietary and medical nutrition. The introduction of high-yielding adaptive varieties is the main condition for increasing the production of camelina sativa. Biotechnological methods are used to increase the efficiency of the selection process. P

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Swanson, L., J. Arnedt, K. DuBuc, T. de Sibour, and H. Burgess. "0039 The Clinical Utility of Dim Light Melatonin Onset in Treatment of Delayed Sleep-Wake Phase Disorder: Preliminary Findings." Sleep 43, Supplement_1 (2020): A16. http://dx.doi.org/10.1093/sleep/zsaa056.038.

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Abstract Introduction Delayed sleep-wake phase disorder (DSWPD) is common, debilitating, and challenging to treat. In an ongoing randomized trial, we are comparing exogenous melatonin treatment outcomes in DSWPD participants for whom dim light melatonin onset (DLMO) is measured objectively vs. estimated. Methods Thus far, 13 participants (27±6 years old, 67% female) have completed a randomized, controlled, double-blind 4-week trial of 0.5 mg of exogenous melatonin timed to either 3 h before measured DLMO (M-DLMO, n = 6) or 3 h before DLMO estimated at 2 h before average sleep onset time based

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Leehey, David J., Kimberly Carlson, Domenic J. Reda, et al. "Pentoxifylline in diabetic kidney disease (VA PTXRx): protocol for a pragmatic randomised controlled trial." BMJ Open 11, no. 8 (2021): e053019. http://dx.doi.org/10.1136/bmjopen-2021-053019.

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IntroductionDiabetic kidney disease (DKD) is the most frequent cause of end-stage renal disease (ESRD) in the USA and worldwide. Recent experimental and clinical data suggest that the non-specific phosphodiesterase inhibitor pentoxifylline (PTX) may decrease progression of chronic kidney disease. However, a large-scale randomised clinical trial is needed to determine whether PTX can reduce ESRD and death in DKD.Methods and analysisVeterans Affairs (VA) PTXRx is a pragmatic, randomised, placebo-controlled multicentre VA Cooperative Study to test the hypothesis that PTX, when added to usual care

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Verma, Reena, and Vatsala Maheshwari. "A Study to Record & Assess the Incidence of Adverse Drug Reactions in Pediatric Patients on Antiepileptic Drugs Reporting in a Tertiary Health Care Center of Central India." International Journal of Pharmaceutical and Clinical Research 14, no. 10 (2022): 492–98. https://doi.org/10.5281/zenodo.13293134.

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<strong>Objective:</strong> To record & assess the incidence of Adverse drug reactions(ADRs) in pediatric patients on antiepileptic drugs(AEDs) reporting in a tertiary health care center of central India. <strong>Method: </strong>A prospective observational study was undertaken for a period of 6 months between February 2019 to August 2019 to analyze adverse drug reactions due to antiepileptic drugs in pediatric department of a tertiary care hospital. Pediatric patients upto18years old were enrolled.  Other parameters like most common class of drug causing ADR, common ty

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Webber, Colleen, David Robert Siemens, Michael Brundage, and Patti A. Groome. "Quality of care indicators and their related outcomes: A population-based study in prostate cancer patients treated with radical prostatectomy." Canadian Urological Association Journal 8, no. 7-8 (2014): 572. http://dx.doi.org/10.5489/cuaj.1649.

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Introduction: We evaluated the validity of 8 quality of care indicators for prostate cancer patients treated curatively with radical prostatectomy (RP) by examining their association with indicator relevant outcomes.Methods: We conducted a population-based retrospective cohort study of 646 prostate cancer patients diagnosed between 1990 and 1998 who received RP within 6 months of diagnosis. Data were collected from treating charts and linked to registry and administrative data. Quality indicators included: hospital volume, pre-treatment risk assessment, consultation with a radiation oncologist

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Coakley, Mariah, Kenneth E. Peck, Tex S. Taylor, Nora S. Matthews, and Katrina L. Mealey. "Pharmacokinetics of flunixin meglumine in donkeys, mules, and horses." American Journal of Veterinary Research 60, no. 11 (1999): 1441–44. http://dx.doi.org/10.2460/ajvr.1999.60.11.1441.

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Abstract Objective To compare serum disposition of flunixin meglumine after IV administration of a bolus to horses, donkeys, and mules. Animals 3 clinically normal horses, 5 clinically normal donkeys, and 5 clinically normal mules. Procedure Blood samples were collected at time zero (before) and 5, 10, 15, 30, and 45 minutes, and at 1, 1.25, 1.5, 1.75, 2, 2.5, 2.75, 3, 3.5, 4, 4.5, 5, 5.5, 6, and 8 hours after IV administration of a bolus of flunixin meglumine (1.1 mg/kg of body weight). Serum was analyzed in duplicate by the use of high-performance liquid chromatography for determination of f

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Chen, Katherine L., Lauren E. Wisk, Teryl K. Nuckols, et al. "Association of Cost-Driven Residential Moves With Health-Related Outcomes Among California Renters." JAMA Network Open 6, no. 3 (2023): e232990. http://dx.doi.org/10.1001/jamanetworkopen.2023.2990.

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ImportanceUnaffordable housing is associated with adverse health-related outcomes, but little is known about the associations between moving due to unaffordable housing and health-related outcomes.ObjectiveTo characterize the association of recent cost-driven residential moves with health-related outcomes.Design, Setting, and ParticipantsThis cross-sectional study involved a weighted multivariable regression analysis of California Health Interview Survey data from January 1, 2011, to December 31, 2017. A population-based sample of 52 646 adult renters and other nonhomeowners in California were

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Sariçam, Tuğba, and İrfan Albayrak B. "Investigation of blood cells of Miniopterus schreibersii (Mammalia: Chiroptera) in Turkey." Turkish Journal of Zoology 43, no. 6 (2019): 636–40. https://doi.org/10.3906/zoo-1902-7.

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Sariçam, Tuğba, B, İrfan Albayrak (2019): Investigation of blood cells of Miniopterus schreibersii (Mammalia: Chiroptera) in Turkey. Turkish Journal of Zoology 43 (6): 636-640, DOI: 10.3906/zoo-1902-7, URL: http://dx.doi.org/10.3906/zoo-1902-7

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Toptygina, A. P., M. A. Smerdova, M. A. Naumova, N. P. Vladimirova, and T. A. Mamaeva. "INFLUENCE OF POPULATION IMMUNITY PECULIARITIES ON THE STRUCTURE OF MEASLES AND RUBELLA PREVALENCE." Russian Journal of Infection and Immunity 8, no. 3 (2018): 341–48. http://dx.doi.org/10.15789/2220-7619-2018-3-341-348.

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According to the lasting serological investigations of patients with rubella and measles, a major factor that determines the resistance to the infections is specific antibodies, that are still circulating in blood of recovered persons during their life. Since vaccinated people are also included in this concept, serological monitoring of people different ages who get vaccinated against rubella and measles is conducted in Russia. However the discrepancy between specific immunity intensity and the measles incidence was showed last years. Using “Vector Best” kits, the study of the anti-measles and

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Bynum, W. F. "SirGordon Wolstenholme (editor), Lives of the Fellows of the Royal College of Physicians (Munk's Roll), Oxford and Washington DC, IRL Press; vol. 6: 1966-75, 1982, 8vo, pp. xi, 505, illus., £25.00; vol. 7: 1976-83, 1984, 8vo, pp. xi, 646, illus., £35.00." Medical History 29, no. 1 (1985): 100–101. http://dx.doi.org/10.1017/s0025727300043805.

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Pooler, Charlotte, Joy Mekechuk, Domhnall O Dochartaigh, Christa Desrochers, and Jude Spiers. "Palliative home care patients’ emergency department visits near end of life: decision making and outcomes." Canadian Journal of Emergency Nursing 43, no. 2 (2020): 16. http://dx.doi.org/10.29173/cjen57.

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Introduction & Aims  Some palliative patients have one or multiple ED visits near their end of life. People who stay home are more likely to die at home or in hospice compared to those admitted to acute care. This study was to describe decisions and outcomes of palliative home care patients who go to Emergency (ED) within the last 6 weeks of life in one metropolitan zone of Alberta Health Services. Description  In the 2017-2018 fiscal year, there were 1874 palliative home care patients in the Edmonton Zone, of whom 646 (34.4 %) patients went to ED in the last 6 weeks of l

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Mallardo, Domenico, Anita Minopoli, Maria Ingenito, et al. "Prognostic implications of glycemia in non-diabetic patients with metastatic melanoma undergoing immunotherapy." Journal of Clinical Oncology 43, no. 16_suppl (2025): 9530. https://doi.org/10.1200/jco.2025.43.16_suppl.9530.

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9530 Background: Immune checkpoint inhibitors (ICIs) have revolutionized the cancer therapeutic landscape, significantly improving the survival of patients (pts) with advanced malignancies. Previous studies have shown that diabetic pts have a higher risk of cancer-related mortality compared to those without diabetes. This retrospective study aimed to investigate the prognostic impact of glycemia on ICI treatment outcomes in non-diabetic metastatic melanoma pts. Methods: Glycemic levels were assessed at three distinct time points within a two-week period prior to the initiation of ICI therapy i

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Jain, Tripti, Harkarandeep Singh, and Peter A. Kouides. "Comparing Anticoagulation Strategies in Left Ventricular Assist Devices - Direct Oral Anticoagulants, No Anticoagulation, and Warfarin: A Case Series and Systematic Review of Literature." Blood 144, Supplement 1 (2024): 5575. https://doi.org/10.1182/blood-2024-210696.

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Introduction Left ventricular assist devices (LVADs) are being used increasingly for medical therapy-resistant heart failure, reducing mortality but associated with bleeding complications due to anticoagulation (AC) use. Vitamin K Antagonists (VKAs) are the standard of care in patients with LVADs, while the safety and efficacy of direct oral anticoagulants (DOACs) remains uncertain. We report our experience of using DOACs or discontinuing AC in patients with LVADs, followed by a systematic review of the literature. Methods We conducted a retrospective, single-center review, identifying patient

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Huynh, Julie, Kate A. Hodgson, Suzanne Boyce, Laila F. Ibrahim, and Penelope A. Bryant. "Impact of expanding a paediatric OPAT programme with an antimicrobial stewardship intervention." Archives of Disease in Childhood 105, no. 12 (2020): 1220–28. http://dx.doi.org/10.1136/archdischild-2019-318091.

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BackgroundAs treatment out of hospital with outpatient parenteral antimicrobial therapy (OPAT) increases, so too does the risk for patients of being less visible, with potential for suboptimal care.ObjectivesWe aimed to compare pre-expansion and post-expansion (1) successful completion, complications and (2) the impact of an OPAT-specific antimicrobial stewardship (AMS) intervention to mitigate inappropriate antibiotic prescribing.DesignA prospective longitudinal study during two consecutive 12-month periods: period A (1 August 2012 to 31 July 2013) and period B (1 August 2013 to 31 July 2014)

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Perez-Rodriguez, *M Mercedes, Kendall Moore, Rebecca Jessel, et al. "PLACENTAL GENE EXPRESSION ASSOCIATED WITH SARS-COV-2 INFECTION AND POSTPARTUM DEPRESSION." International Journal of Neuropsychopharmacology 28, Supplement_1 (2025): i188—i189. https://doi.org/10.1093/ijnp/pyae059.326.

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Abstract Background Recent meta-analyses showed that around 30% of women suffered postpartum depression during the COVID-19 pandemic, a two-fold increase compared to before the pandemic (1,2,3). The immune system plays a key role in responding to infections, and is a potential mechanism in the development of psychiatric disorders. The placenta is a driver of immune changes during pregnancy, modulating the maternal immune response to perinatal infections (4). Aims & Objectives To investigate: 1) whether SARS-CoV2 infection during pregnancy is associated with expression of immune and inflamm

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Nair, Bijay, Elias J. Anaissie, Sarah Waheed, et al. "Autotransplants for Multiple Myeloma (MM) – An Update of the Arkansas Experience Since 1989 In Almost 4000 Patients with Special Emphasis on Third and Further Transplants." Blood 116, no. 21 (2010): 1352. http://dx.doi.org/10.1182/blood.v116.21.1352.1352.

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Abstract Abstract 1352 Background: The Arkansas program has emphasized high hematopoietic progenitor cell (HPC) yields since its inception in 1989, in order to enable further high-dose therapy for relapse, rescue patients from hematopoietic compromise due to extensive cumulative genotoxic or novel agent dosing, and provide a fall-back option in the case MDS develops. Here we are examining the overall outcome data among 3888 patients undergoing HPC-supported therapy since 1989. Patients and Methods: Patients were grouped according to whether they received front-line Total Therapy (TT) protocols

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Singh, Prabhsimranjot, Makardhwaj S. Shrivastava, Daniel Benasher, Audrik Perez, and Philip Rubin. "Curious Case of Profound Thrombocytopenia in a Pregnant Woman." Blood 128, no. 22 (2016): 4944. http://dx.doi.org/10.1182/blood.v128.22.4944.4944.

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Abstract Introduction: Pseudo-thrombocytopenia (PTCP) is a benign artifact which generates anxiety in the patients and physicians resulting in unnecessary investigations. We report a case with profound artefactual thrombocytopenia. Case: A 31-years-old female in 38th week of gestation was referred to hematology clinic for evaluation of a platelet count of 48x109/L. A month ago platelet count was 102x109/L. She denied any symptoms. Examination was normal with no ecchymosis or petechiae. Laboratory work showed a white cell count of 11.2x109/L, hemoglobin 10.3g/L, platelet count 8x109/L and no he

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Shoji, Y., E. Tanaka, S. Yamamoto, H. Maeda, and H. Higashi. "Mechanisms Underlying the Enhancement of Excitatory Synaptic Transmission in Basolateral Amygdala Neurons of the Kindling Rat." Journal of Neurophysiology 80, no. 2 (1998): 638–46. http://dx.doi.org/10.1152/jn.1998.80.2.638.

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Shoji, Y., E. Tanaka, S. Yamamoto, H. Maeda, and H. Higashi. Mechanisms underlying the enhancement of excitatory synaptic transmission in basolateral amygdala neurons of the kindling rat. J. Neurophysiol. 80: 638–646, 1998. To elucidate the mechanism underlying epileptiform discharges in kindled rats, synaptic responses in kindled basolateral amygdala neurons in vitro were compared with those from control rats by using intracellular and whole cell patch-clamp recordings. In kindled neurons, electrical stimulation of the stria terminalis induced epileptiform discharges. The resting potential, a

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