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Journal articles on the topic '656.7.072 (045)'

Author: Grafiati

Published: 30 May 2022

Last updated: 31 July 2025

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1

Gallyamov, Eldar M., Vladimir V. Titkov, Vladimir N. Lebedev, Sergey Y. Stefanovich, Bogdan I. Lazoryak, and Dina V. Deyneko. "Mn2+ Luminescence in Ca9Zn1–xMnxNa(PO4)7 Solid Solution, 0 ≤ x ≤ 1." Materials 16, no. 12 (2023): 4392. http://dx.doi.org/10.3390/ma16124392.

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The solid solution Ca9Zn1–xMnxNa(PO4)7 (0 ≤ x ≤ 1.0) was obtained by solid-phase reactions under the control of a reducing atmosphere. It was demonstrated that Mn2+-doped phosphors can be obtained using activated carbon in a closed chamber, which is a simple and robust method. The crystal structure of Ca9Zn1–xMnxNa(PO4)7 corresponds to the non-centrosymmetric β-Ca3(PO4)2 type (space group R3c), as confirmed by powder X-ray diffraction (PXRD) and optical second-harmonic generation methods. The luminescence spectra in visible area consist of a broad red emission peak centered at 650 nm under 406

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Self, Wesley H., Matthew S. Shotwell, Kevin W. Gibbs, et al. "Renin-Angiotensin System Modulation With Synthetic Angiotensin (1-7) and Angiotensin II Type 1 Receptor–Biased Ligand in Adults With COVID-19." JAMA 329, no. 14 (2023): 1170. http://dx.doi.org/10.1001/jama.2023.3546.

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ImportancePreclinical models suggest dysregulation of the renin-angiotensin system (RAS) caused by SARS-CoV-2 infection may increase the relative activity of angiotensin II compared with angiotensin (1-7) and may be an important contributor to COVID-19 pathophysiology.ObjectiveTo evaluate the efficacy and safety of RAS modulation using 2 investigational RAS agents, TXA-127 (synthetic angiotensin [1-7]) and TRV-027 (an angiotensin II type 1 receptor–biased ligand), that are hypothesized to potentiate the action of angiotensin (1-7) and mitigate the action of the angiotensin II.Design, Setting,

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Lye, Ching T., Swarup Mukherjee, and Stephen F. Burns. "Combining Plant Sterols With Walking Lowers Postprandial Triacylglycerol More Than Walking Only in Chinese Men With Elevated Body Mass Index." International Journal of Sport Nutrition and Exercise Metabolism 29, no. 6 (2019): 576–82. http://dx.doi.org/10.1123/ijsnem.2018-0398.

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This study examined if plant sterols and walking reduce postprandial triacylglycerol (TAG) concentrations in Chinese men with elevated body mass index (≥ 23.5 kg/m2). Fifteen Chinese men (mean [SD]: age = 25 [3] years and body mass index = 26.2 [1.5] kg/m2] completed four 10-day trials in random order with a 7- to 10-day washout between trials: (a) daily consumption of a control margarine while sedentary (C-S), (b) daily consumption of margarine containing 2 g/day of plant sterols while sedentary (PS-S), (c) daily consumption of a control margarine with 30-min daily walking (C-W), and (d) dail

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Mathew, Gina, Nicole Nahmod, Lindsay Master, David Reichenberger, Asher Rosinger, and Anne-Marie Chang. "0198 Effects of a 1-hour nightly weeklong sleep extension pilot study in undergraduates on health." SLEEP 46, Supplement_1 (2023): A88. http://dx.doi.org/10.1093/sleep/zsad077.0198.

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Abstract Introduction Sleep restriction impairs health, but less is known about the potential health benefits of extending sleep in undergraduate students with habitual short sleep. This study examined the effects of a 1-week, 1-hour per night sleep extension on cardiometabolic health, hydration status, sedentary behavior, and physical activity in undergraduate students. Methods Twelve healthy undergraduate students (83% female; mean±SD age 20.2±1.5; range 18-23 years) obtaining fewer than 7 hours of average nightly sleep completed a two-week study. The first week consisted of sleeping typical

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Nguyen Ngoc, Chinh, and Sho Shirakashi. "The first record of \(\textit{Kudoa yasunagai}\) (Hsieh & Chen, 1984) (Myxosporea: Multivalvulida) parasitizing the brain of barhead spinefoot \(\textit{Siganus virgatus}\) (Valenciennes) from Vietnam." Academia Journal of Biology 46, no. 1 (2024): 87–97. http://dx.doi.org/10.15625/2615-9023/19453.

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A brain-infecting myxozoan, Kudoa yasunagai (Hsieh & Chen, 1984), was identified using both morphological and molecular methods in a marine fish from Van Phong Bay, Khanh Hoa province, Vietnam. Cysts containing spores were observed in the brain of one out of 10 Siganus virgatus (Valenciennes) individuals (10%). The myxospores were radially symmetrical, containing a majority of 7 equal shell valves and polar capsules. The spores measured 6.6 ± 0.1 (6.4‒6.7) µm in length, 7.6 ± 0.5 (7.0‒8.4) µm in width, and 7.0 ± 0.4 (6.5‒7.7) µm in thickness. Polar capsules measured 2.8 ± 0.2 (2.6‒3.0) µm

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Potham Naidu, Rohan. "New constraints on reionization from a redshift-independent efficiency model." Proceedings of the International Astronomical Union 15, S352 (2019): 70. http://dx.doi.org/10.1017/s174392132000112x.

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AbstractWe present an empirical model built on a high-resolution N-body dark matter simulation. We assume a redshift-independent star-formation efficiency for each halo to convert the accretion rate into a star-formation rate. Our model is calibrated using the z = 4 UV luminosity function (UVLF) and successfully predicts the observed UVLF at z = 5 – 10. We present predictions at z = 5 – 10 for UV luminosity and stellar mass functions, JWST number counts, the stellar-to-halo mass relation and star-formation histories. We combine this model with bleeding-edge reionization constraints (from z &gt

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Nordine, Michael, Marius Pille, Jan Kraemer, et al. "Intraoperative Beat-to-Beat Pulse Transit Time (PTT) Monitoring via Non-Invasive Piezoelectric/Piezocapacitive Peripheral Sensors Can Predict Changes in Invasively Acquired Blood Pressure in High-Risk Surgical Patients." Sensors 23, no. 6 (2023): 3304. http://dx.doi.org/10.3390/s23063304.

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Background: Non-invasive tracking of beat-to-beat pulse transit time (PTT) via piezoelectric/piezocapacitive sensors (PES/PCS) may expand perioperative hemodynamic monitoring. This study evaluated the ability for PTT via PES/PCS to correlate with systolic, diastolic, and mean invasive blood pressure (SBPIBP, DBPIBP, and MAPIBP, respectively) and to detect SBPIBP fluctuations. Methods: PES/PCS and IBP measurements were performed in 20 patients undergoing abdominal, urological, and cardiac surgery. A Pearson’s correlation analysis (r) between 1/PTT and IBP was performed. The predictive ability o

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Issa, Ghayas C., Hagop M. Kantarjian, C. Cameron Yin, et al. "Prognostic Implications of Pre-Treatment Hypodiploidy and Complex Cytogenetics in Adult Patients with Acute Lymphocytic Leukemia (ALL) Treated with Hyper-CVAD." Blood 126, no. 23 (2015): 4874. http://dx.doi.org/10.1182/blood.v126.23.4874.4874.

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Abstract Background Pretreatment cytogenetic analysis is frequently used to predict response and outcome in hematologic malignancies. Hypodiploidy is associated with a poor prognosis in childhood ALL. Similarly, complex cytogenetics is a known adverse prognostic factor in myeloid malignancies. The impact of hypodiploidy and complex cytogenetics has not been extensively assessed in adult patients with ALL. To address this issue, we have conducted a retrospective analysis of all adult patients with ALL treated with frontline Hyper-CVAD based regimens at our institution. Methods We reviewed 332 a

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Hartati, Juli, Sitti Ahmiatri Saptari, and Arif Tjahjono. "Analysis Crystal Structure of La0.7Ba(1-xSrx)0.3MnO3 by Sol-Gel Method." Al-Fiziya: Journal of Materials Science, Geophysics, Instrumentation and Theoretical Physics 3, no. 1 (2020): 35–41. http://dx.doi.org/10.15408/fiziya.v3i1.15029.

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Abstrak.Penelitian tentang struktur kristal bahan La0.7(Ba1-xSrx)MnO3 menggunakan metode sol-gel telah berhasil dilakukan. Bahan-bahan dasar yang digunakan dicampur di atas hot plate diaduk sambil ditetesi ammonia solution sehingga mencapai pH 7, selanjutnya didiamkan sampai diperoleh bentuk gel. Gel dikeringkan pada suhu 120°C, selanjutnya dilakukan pra-kalsinasi dengan suhu 650°C selama 6 jam, dilanjutkan dengan kalsinasi pada suhu 1000°C selama 12 jam, dan kemudian disinter pada temperatur 1200°C selama 12 jam. Hasil refinement data XRD memberikan informasi bahwa struktur kristal La0.7(Ba1-

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A, Garagozzo, Hunter S, and Smith D. "A-042 Incongruence Between Self- and Parent- Report Measures of Executive Function on the Behavior Rating Inventory of Executive Function (BRIEF) in Adolescents with Attention Deficit Hyperactivity Disorder." Archives of Clinical Neuropsychology 35, no. 6 (2020): 832. http://dx.doi.org/10.1093/arclin/acaa068.042.

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Abstract Objective Research has demonstrated that adolescents with ADHD show executive dysfunction, although they do not always endorse such difficulties. We investigated inter-rater agreement between parent- and self-reported executive function (EF) in adolescents with ADHD, using the BRIEF. We also sought to investigate the relationship between scores on parent and self-report EF measures with performance on objective EF measures. Method Utilizing a clinical database, we identified 75 participants (13-17 years; Mage = 14.9; 60% male; 27% African American, 63% White, 3% Hispanic, 7% Other) wi

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Losnegard, Thomas, and Jostein Hallén. "Physiological Differences Between Sprint- and Distance-Specialized Cross-Country Skiers." International Journal of Sports Physiology and Performance 9, no. 1 (2014): 25–31. http://dx.doi.org/10.1123/ijspp.2013-0066.

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Purpose:Sprint- (≤1.8 km) and distance-skiing (≥15 km) performance rely heavily on aerobic capacity. However, in sprint skiing, due to the ~20% higher speed, anaerobic capacity contributes significantly. This study aimed to identify the possible anthropometric and physiological differences between elite male sprint and distance skiers.Methods:Six sprint and 7 distance international-level cross-country skiers completed testing using the V2 skating technique on a roller-ski treadmill. Measurements included submaximal O2 cost (5°, 3 m/s) and a 1000-m time trial (6°, >3.25 m/s) to assess VO2pea

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Pekov, Igor V., Natalia V. Zubkova, Vasiliy O. Yapaskurt, et al. "Kainotropite, Cu4Fe3+O2(V2O7)(VO4), a new mineral with a complex vanadate anion from fumarolic exhalations of the Tolbachik volcano, Kamchatka, Russia." Canadian Mineralogist 58, no. 2 (2020): 155–65. http://dx.doi.org/10.3749/canmin.1900073.

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ABSTRACT The new mineral kainotropite Cu4Fe3+O2(V2O7)(VO4) was found in sublimates of fumaroles related to the Tolbachik volcano, Kamchatka, Russia. The holotype specimen originates from the Yadovitaya fumarole at the Second scoria cone of the Northern Breakthrough of the Great Tolbachik Fissure Eruption; associated minerals are hematite, langbeinite, calciolangbeinite, tenorite, piypite, lyonsite, rutile, pseudobrookite, sanidine, and lammerite. In paleo-fumarolic deposits of Mountain 1004 kainotropite is associated with diopside and hematite. It forms prismatic crystals up to 0.2 × 0.2 × 0.5

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Sánchez Romo, S. M., D. E. Flores Alvarado, J. C. López Zamarrón, M. A. Villarreal-Alarcón, I. D. J. Hernandez-Galarza, and D. Á. Galarza-Delgado. "SAT0599 FEET DERMATOLOGICAL CONDITIONS AND DEFORMITIES IN RHEUMATOID ARTHRITIS." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1258.2–1258. http://dx.doi.org/10.1136/annrheumdis-2020-eular.5132.

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Background:It has been extensively studied the repercussions of rheumatoid arthritis (RA) in hands and in their function. However, the evidence regarding the effect on feet and dermatological problems is scarce1.Objectives:Describe risk factors associated with foot deformities (FD) in patients with RA.Methods:This was a descriptive and observational cross-sectional study. Patients were consecutively recruited. Demographic-clinical data was registered and through physical examination the presence of FD, dermatological problems and pain location were assessed. The Foot Function Index (FFI) surve

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Ebarb, Sara, Richard Faris, Junmei Zhao, Sabrina Williams, and Kathryn Price. "153 Impacts of two energy sources (modified soy oil and medium chain triglycerides) on growth performance and health of nursery pigs." Journal of Animal Science 97, Supplement_2 (2019): 89. http://dx.doi.org/10.1093/jas/skz122.161.

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Abstract This study evaluated the effects of a modified soy oil (MSO) in diets with or without medium chain triglycerides from palm kernel oil (MCT). The study utilized 1,840 pigs (~19 d of age; 5.4 ± 0.2 kg), 10 pens/treatment, and ~22 pigs/pen. Two barns were blocked separately by pen location and randomly allocated to treatments. Treatments were arranged as a 2 × 4 factorial utilizing diets containing one of four levels of MSO (0, 0.15, 0.25, or 0.40%) and two levels of MCT [without vs with (0.50% d 0 to 7; 0.25% d 7 to 41)]. Pen weights were obtained on d 0, 7, 23, and 41 post-weaning, mor

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Sierra-Díaz, Diana Carolina, Adrien Morel, Dora Janeth Fonseca, et al. "Abstract P3-07-05: Genetic profile of germline mutations in unselected women with breast cancer in a Colombian population." Cancer Research 82, no. 4_Supplement (2022): P3–07–05—P3–07–05. http://dx.doi.org/10.1158/1538-7445.sabcs21-p3-07-05.

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Abstract Introduction In Colombia Breast cancer (BC), is the most frequent and has the highest mortality rate among all types of cancer. There are few studies of the genomic profile in unselected affected population by BC in Colombia. Some of these studies have only tested the presence of variants reported as founders named “Colombian Profile”.We conducted a large-scale genomic analysis using Whole Exome Sequencing (WES) to evaluate germline mutations in unselected BC patients. Methods This trial included 299 unselected BC female patients aged over 18 years old, without personal and family his

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McDonald, Colin P., Victor Chang, Michael McDonald, Nicole Ramo, Michael J. Bey, and Stephen Bartol. "Three-dimensional motion analysis of the cervical spine for comparison of anterior cervical decompression and fusion versus artificial disc replacement in 17 patients." Journal of Neurosurgery: Spine 20, no. 3 (2014): 245–55. http://dx.doi.org/10.3171/2013.11.spine13392.

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Object Cervical arthroplasty with an artificial disc (AD) has emerged as an alternative to anterior cervical discectomy and fusion (ACDF) for the management of cervical spondylosis. This study aims to provide 3D motion analysis data comparing patients after ACDF and AD replacement. Methods Ten patients who underwent C5–6 ACDF and 7 who underwent C5–6 AD replacement were enrolled. Using biplanar fluoroscopy and a model-based track technique (accurate up to 0.6 mm and 0.6°), motion analysis of axial rotation and flexion-extension of the neck was performed. Three nonoperative segments (C3–4, C4–5

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Ratnawulan, R., Suchi R. Putri, Dian Septiana, Sisi Gusti Putri, and A. Fauzi. "The Effect of Acid, Salt and Base Immersion on Hydrophobic Properties of SiMn/PS Nanocomposite." Journal of Physics: Conference Series 2309, no. 1 (2022): 012024. http://dx.doi.org/10.1088/1742-6596/2309/1/012024.

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Abstract The manufacture of hydrophobic coatings that have self-cleaning properties has become a research trend now, but when applied, the coating is still easily damaged due to contact with other objects and is not durable due to corrosion. This problem will certainly hinder the application of hydrophobic surfaces in industry. For this reason, the researchers mixed substrates that had anti-corrosion properties such as silica and hard and strong properties such as manganese to be able to solve the previous problem, and the method used is spin coating. The precursors were made by adding 0.5 gra

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Woods, L. L., B. E. Smith, and D. R. De Young. "Control of renal hemodynamics after protein feeding: role of calcium channels." American Journal of Physiology-Renal Physiology 263, no. 6 (1992): F1044—F1050. http://dx.doi.org/10.1152/ajprenal.1992.263.6.f1044.

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This study was designed to test the hypothesis that the changes in renal hemodynamics that occur after a high-protein meal involve voltage-dependent calcium channels. In chronically instrumented female dogs, a 10-g/kg meal of raw beef caused plasma alpha-amino nitrogen levels to increase from 3.9 +/- 0.2 to 6.7 +/- 0.5 mg/dl after 90 min, and glomerular filtration rate (GFR) rose from 59 +/- 6 to 85 +/- 7 ml/min, effective renal plasma flow (ERPF) rose from 130 +/- 22 to 213 +/- 36 ml/min, and sodium excretion rose from 21 +/- 4 to 84 +/- 20 mu eq/min. On another day the dogs were pretreated w

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Porter, J., C. Borgna-Pignatti, M. Baccarani, et al. "Iron Chelation Efficiency of Deferasirox (Exjade®, ICL670) in Patients with Transfusional Hemosiderosis." Blood 106, no. 11 (2005): 2690. http://dx.doi.org/10.1182/blood.v106.11.2690.2690.

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Abstract Iron excretion can be calculated according to Angelucci et al (NEJM 2000). As applied to the novel oral iron chelator deferasirox (DSX), chelation efficiency can then be determined as the % iron excretion vs theoretical iron binding capacity of chelator dose: % efficiency = [iron excretion (mg/kg/day)/chelator dose (mg/kg/day)] x [374/56] x 2 x 100 (374 and 56 represent the molecular weights of DSX and iron; factor 2 accounts for the tridentate ligand). In a total of 325 patients with β-thalassemia (n=285) or rare anemias, such as MDS (n=13), DBA (n=14) or other anemias (n=13), includ

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Naik, Mude Bhaskar, Vinayak S. Sirsat, Shailendra Chauhan, and Deepak M. Kokane. "A Comparison of Analgesic Effect of Different Doses of Intrathecal Nalbuphine Hydrocloride with Bupivacaine and Bupivacaine alone for Lower Abdominal and Orthopedic Surgeries." Indian Journal of Anesthesia and Analgesia 9, no. 1 (2022): 15–19. http://dx.doi.org/10.21088/ijaa.2349.8471.9122.2.

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Objective: To compare the analgesic effect of different doses of nalbuphine when added to bupivacaine in spinal anaesthesia. To compare the onset of sensory blockade (time taken form 3, 5 min and then every 5 min until the end of the procedure. Methods: 100 ASA grade 1 and 2 patients grouped into group A, group B, group C and group D randomly. Age group of 18-60 years. Patient undergoing elective lower abdominal and orthopedic surgery received with Group A : included 25patients with 0.5% hyperbaric bupivacaine 3 cc (15mg) + N.S. 0.2 ml. Group B: included 25 patients with 0.5% hyperbaric bupiva

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Liliia, Vyshnevska, Strilets Oksana, and Vladyslav Postoy. "Studies on the design of a composition of gel for the treatment of inflammatory diseases of the joints." ScienceRise: Pharmaceutical Science, no. 6(16) (December 28, 2018): 4–8. https://doi.org/10.15587/2519-4852.2018.151447.

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<strong>The aim: </strong>the aim of our work was to experimentally substantiate the effectiveness of antimicrobial preservatives in the design of the composition of the combined gel for the treatment of acute and chronic inflammation of the joints. <strong>Methods:</strong> biological pharmacopoeial method of research was used (research of the effectiveness of antimicrobial preservatives). <strong>Results.</strong> All drugs must meet the requirements of regulatory documents on indicators "Microbiological purity." To ensure the microbiological stability of the prepara

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Amare, Gashaw, Beyene Dobo, and Ermias Haile. "The Effect of Wet Coffee Processing Plant Effluent on Physicochemical and Bacteriological Quality of Receiving Rivers Used by Local Community: Case of Aroresa District, Sidama, Ethiopia." Environmental Health Insights 17 (January 2023): 117863022311651. http://dx.doi.org/10.1177/11786302231165186.

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Freshwater bodies such as lakes, rivers, and their biodiversity are being threatened with water pollution from industrial effluents and household sewages. The main objective of this study is to assess the effects of wet coffee processing plants effluent on the physicochemical and bacteriological properties of receiving rivers. Four rivers and 4 sampling points of the selected rivers were included in the study. Focus group discussion and interview were employed to gather primary data. The result showed that parameters of water quality for downstream of the rivers were significant, particularly

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Parker, Pablo M., Ryotaro Nakamura, Vinod Pullarket, et al. "Analysis of Predictive Power of Prednisone Dose at 3 Months of Treatment on CGVHD Prognosis." Blood 110, no. 11 (2007): 1975. http://dx.doi.org/10.1182/blood.v110.11.1975.1975.

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Abstract Current CGVHD prognostic and staging systems are still undergoing development and have identified plt count; CGVHD types progressive(P), quiescent(Q), de novo(DN); KPS, and GI involvement as significant risk factors affecting outcome. A simple reproducible staging system such as used for AGVHD to apply in clinical trials is still lacking. We evaluated whether the PSE dose required to control CGVHD at 3 months from diagnosis would have a prognostic effect on survival and in and of itself serve as a criteria for secondary intervention or investigational therapy. We hypothesized that by

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Grey, Ian E., Rupert Hochleitner, Christian Rewitzer, et al. "The walentaite group and the description of a new member, alcantarillaite, from the Alcantarilla mine, Belalcázar, Córdoba, Andalusia, Spain." Mineralogical Magazine 84, no. 3 (2020): 412–19. http://dx.doi.org/10.1180/mgm.2020.18.

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AbstractThe general structural formula for the walentaite group is [((A1yA1’1–y), A2)(H2O)n][Bx(As2)2–x(As3)M1(M2)2(TO4)2(O,OH)7], based on heteropolyhedral layers of configuration [M1(M2)2(TO4)2(O,OH)6], with surface-coordinated species at the B, As2 and As3 sites, and with interlayer hydrated cation groups centred at the A sites. The group is divided into walentaite and halilsarpite subgroups based on T = P5+ and As5+, respectively. Alcantarillaite, (IMA2019-072), [Fe3+0.5□0.5(H2O)4][CaAs3+2(Fe3+2.5W6+0.5)(AsO4)2O7], is a new member of the walentaite group from the Alcantarilla wolframite mi

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Tang, Lianyao, and Peiming Peng. "Research on Surface Roughness and Surface Topography of TC4 Titanium Alloy Processed by High-Speed Turning." Journal of Physics: Conference Series 2941, no. 1 (2025): 012012. https://doi.org/10.1088/1742-6596/2941/1/012012.

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Abstract Titanium alloy is a typical difficult to process material, in order to further improve the processing quality. In this study, the single factor experiment method was used to perform high-speed turning experiments on TC4 titanium alloy with TiAlSiN carbide coated blade. The experimental results show that the cutting speed (Vc), feed per tooth (fz), and cutting depth (ap) have certain effects on the surface roughness of TC4 titanium alloy. When the feed per tooth increases from 0.04 mm/r to 0.2 mm/r, the surface roughness value (Ra) increases by 7 times. In the cutting speed range of 40

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Saxena, A., S. Parikh, S. Hua, R. Leff, E. Park, and N. Henig. "POS1128 ZETOMIPZOMIB (KZR-616) TREATMENT RESULTS IN CLINICALLY MEANINGFUL RENAL RESPONSES IN PATIENTS WITH LUPUS NEPHRITIS." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 891–92. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2317.

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BackgroundZetomipzomib, a first-in-class selective inhibitor of the immunoproteasome blocks multiple pathways involved in inflammatory cytokine production and immune effector cell activity – including macrophages, B cells and T cells leading to broad immunomodulation across both the innate and adaptive immune systems[1-3]. The MISSION Phase 1b/2, open-label study (NCT03393013; KZR-616-002) evaluated safety, tolerability, and exploratory efficacy of zetomipzomib in patients with systemic lupus erythematosus (SLE) +/- lupus nephritis (LN). In the Phase 1b portion, zetomipzomib was well-tolerated

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Cortes, Jorge, Fabian Lang, Delphine Rea, et al. "Asciminib (ASC) in Combination with Imatinib (IMA), Nilotinib (NIL), or Dasatinib (DAS) May be a Potential Treatment (Tx) Option in Patients (Pts) with Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase or Accelerated Phase (Ph+ CML-CP/AP): Final Results from the Asciminib Phase 1 Study." Blood 142, Supplement 1 (2023): 868. http://dx.doi.org/10.1182/blood-2023-189270.

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CONCLUSIONS ATP-competitive tyrosine kinase inhibitors (TKIs) have extended the life expectancy of pts with CML. However, Tx resistance remains an issue with ATP-competitive TKIs. ASC is the only approved BCR::ABL1 inhibitor that Specifically Targets the ABL Myristoyl Pocket (STAMP), differing from ATP-competitive TKIs, which bind the ATP-binding site. Preclinical studies of ASC combined with ATP-competitive TKIs showed suppression of BCR::ABL1 mutants, suggesting the potential for enhanced BCR::ABL1 inhibition via combination therapy. In a phase 1 study (NCT02081378), ASC monotherapy showed d

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Lyman, Gary H., Marek S. Poniewierski, Adane Fekadu Wogu, et al. "Association of survival with chemotherapy intensity, myelosuppression, and supportive care in patients with advanced solid tumors." Journal of Clinical Oncology 31, no. 15_suppl (2013): 6534. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.6534.

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6534 Background: The value of chemotherapy and supportive care for advanced cancer has been questioned. Two systematic reviews were conducted to study the impact of chemotherapy-induced myelosuppression and supportive care on subsequent survival. Methods: Phase 1 identified trials evaluating the relationship of chemotherapy associated with myelosuppression and subsequent survival in patients with cancer. Phase 2 evaluated randomized controlled trials (RCTs) chemotherapy with or without G-CSF support for advanced cancer. Outcomes included hazard ratios (HR), relative risk (RR) and absolute risk

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Siopis, George, George Moschonis, Kyriakos Reppas, et al. "The Emerging Prevalence of Obesity within Families in Europe and its Associations with Family Socio-Demographic Characteristics and Lifestyle Factors; A Cross-Sectional Analysis of Baseline Data from the Feel4Diabetes Study." Nutrients 15, no. 5 (2023): 1283. http://dx.doi.org/10.3390/nu15051283.

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The Feel4Diabetes study is a type 2 diabetes prevention program that recruited 12,193 children [age: 8.20 (±1.01) years] and their parents from six European countries. The current work used pre-intervention data collected from 9576 children–parents pairs, to develop a novel family obesity variable and to examine its associations with family sociodemographic and lifestyle characteristics. Family obesity, defined as the presence of obesity in at least two family members, had a prevalence of 6.6%. Countries under austerity measures (Greece and Spain) displayed higher prevalence (7.6%), compared t

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Kalmeijer, Mathijs D., Ella van Nieuwland-Bollen, Diane Bogaers-Hofman, Gerard A. J. de Baere, and Jan A. J. W. Kluytmans. "Nasal Carriage of Staphylococcus aureus: Is a Major Risk Factor for Surgical-Site Infections in Orthopedic Surgery." Infection Control & Hospital Epidemiology 21, no. 5 (2000): 319–23. http://dx.doi.org/10.1086/501763.

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AbstractObjective:To determine the relative importance of different risk factors for the development of surgical-site infections (SSIs) in orthopedic surgery with prosthetic implants.Design:In a cohort of 272 patients, the following possible risk factors were studied: age, gender, method of hair removal, duration of operation, surgeon, underlying illness, and nasal carriage of Staphylococcus aureus. Infections were recorded following the Centers for Disease Control criteria. The relation between risk factors and SSI was tested in univariate and multiple logistic regression analysis.Setting:Com

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Kepert, Cameron J., Lu Wei-Min, Peter C. Junk, Brian W. Skelton, and Allan H. White. "Structural Systematics of Rare Earth Complexes. XI (‘Maximally’) Hydrated Rare Earth(III) Trifluoro- and Trichloro-acetates." Australian Journal of Chemistry 52, no. 6 (1999): 459. http://dx.doi.org/10.1071/ch98042.

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Room-temperature single-crystal X-ray structure determinations carried out on ‘maximally’ hydrated rare earth(III) trifluoroacetates, Ln(tfa)3.x H2O, crystallized at room temperature, show the Ln = La, Ce adducts to be isomorphous and monoclinic, P 21/c, a ≈ 11·9, b ≈ 12·8, c ≈ 9·8 8 Å, β ≈ 103·7°, Z = 4; they are trihydrates. The Ln = Pr, Lu (and, implicitly, intermediate Ln) adducts are also monoclinic, P 21/c, Z = 4, and trihydrates, but of a different polymorph, with a ≈ 9·2, b 18·8, c ≈ 9·8 Å, β ≈ 114°. For the four determinations, conventional R values on |F| were 0·038, 0·032, 0·036, an

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Xu, Xiangyi, Marcos E. Duarte, and Sung Woo Kim. "PSXVI-7 Supplemental effects of Lactobacillus extract postbiotics in prevention of post-weaning diarrhea caused by enterotoxigenic F18+ Escherichia coli in nursery pigs." Journal of Animal Science 99, Supplement_3 (2021): 416. http://dx.doi.org/10.1093/jas/skab235.749.

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Abstract This study determined the supplemental effects of Lactobacillus extract (LBE) postbiotics on intestinal health and prevention of postweaning diarrhea caused by F18+ Escherichia coli (ETEC) in nursery pigs. Sixty-four weaned pigs (6.6 ± 0.7 kg BW) were allotted in a RCBD to 4 dietary treatments (NC: no-challenge; PC: challenge/no-treat; BMD: challenge/bacitracin; LBE: challenge/LBE 0.2%) and fed diets for 28 d. At d 7, challenged groups were orally inoculated with ETEC (2.4 x 1010 CFU) and NC group received sterile solution. Growth performance was analyzed weekly and pigs were euthaniz

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Talib, R. A., N. M. Rashid, R. A. Rahman, N. Mohamad, R. Sukor, and M. Mohamad Mazlan. "Coomans plot classification of lard in the ink blends and ink extracts from printed packaging films using lard Fourier transform infrared spectral profile and multivariate analysis." Food Research 8, no. 4 (2024): 108–16. http://dx.doi.org/10.26656/fr.2017.8(4).002.

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Lard in blends of commercial gravure ink (ranging from 0.5 to 20%) and ink extracts from eleven commercially printed packaging films for foodstuffs was characterized using Fourier transform infrared (FTIR) spectroscopy. The FTIR spectral bands at 4000 ‒ 650 cm-1 associated with the lard fingerprint were acquired and used to classify the lard and its blends using partial least squares (PLS) regression and discriminant analysis (DA). Commercial gravure inks (also used for preparing calibration curve samples), blends of lard ranging from 0.5 to 20% in gravure inks, and commercially printed food p

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Katsube, Yasuhiro, Hisashi Yokoshiki, Lam Nguyen, Masao Yamamoto, and Nicholas Sperelakis. "L-type Ca2+ currents in ventricular myocytes from neonatal and adult rats." Canadian Journal of Physiology and Pharmacology 76, no. 9 (1998): 873–81. http://dx.doi.org/10.1139/y98-076.

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Postnatal changes in the slow Ca2+ current (ICa(L)) were investigated in freshly isolated ventricular myocytes from neonatal (1-7 days old) and adult (2-4 months old) rats, using whole-cell voltage clamp and single-channel recordings. The membrane capacitance (mean ± SEM) averaged 23.2 ± 0.5 pF in neonates (n = 163) and 140 ± 4.1 pF in adults (n = 143). ICa(L) was measured as the peak inward current at a test potential of +10 mV (or +20 mV) by applying a 300-ms pulse from a holding potential of -40 mV; 1.8 mM Ca2+ was used as charge carrier. The basal ICa(L) density was 6.7 ± 0.2 pA/pF in neon

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Bowmaker, Graham A., Peter C. Junk, Aaron M. Lee, Brian W. Skelton, and Allan H. White. "Synthetic, Structural and Vibrational Spectroscopic Studies in Bismuth(III) Halide/N,N′-Aromatic Bidentate Base Systems. I Large-Cation (2,2′-Bipyridinium and 1,10-Phenan- throlinium) Salts of Polyhalobismuthate(III) Ions." Australian Journal of Chemistry 51, no. 4 (1998): 293. http://dx.doi.org/10.1071/c97036.

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Syntheses and room-temperature single-crystal X-ray studies are recorded for a variety of salts of cations derived from protonated 2,2′-bipyridine and 1,10-phenanthroline (bpyH+ and phenH+) with polyhalobismuthate(III) anions. ‘[(phenH)(phenH2)(H2O)2] [BiCl6]’ is triclinic, P-1, a 9·791(1), b 9·338(3), c 8·311(3) Å, α 73·46(3), β 69·71(2), γ 86·36(2)°, Z = 1; conventional R on |F| was 0·027 for No 4852 independent ‘observed’ (I > 3σ(I)) reflections. [BiCl6]3- is closely octahedral, accompanied by an interesting protonation/hydrogen-bonding array among the other moieties. The latter comment

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Shabek, Fathya, Božidar Obradović, Igor Čeliković, et al. "The Radon Exhalation Rate and Dose Assessment of Granite Used as a Building Material in Serbia." Atmosphere 15, no. 12 (2024): 1495. https://doi.org/10.3390/atmos15121495.

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The application of energy-saving policies in buildings could lead to a decrease in the air exchange rate in dwellings, which could consequently lead to an increase in indoor radon concentration and, therefore, to an increase in resident exposure to ionizing radiation. The aim of the research presented in this paper is to investigate radiological exposure to residents due to the usage of different granites commonly used in Serbia as a building material. From the total of 10 analysed granite samples, a wide range of radon and thoron exhalation rates were found: from <161 μBq m−2 s−1 to 5220 ±

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Djekic-Ivankovic, Marija, Hope Weiler, Glenville Jones, et al. "Vitamin D status in mothers with pre-eclampsia and their infants: a case–control study from Serbia, a country without a vitamin D fortification policy." Public Health Nutrition 20, no. 10 (2016): 1825–35. http://dx.doi.org/10.1017/s1368980016000409.

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AbstractObjectiveThe objective of the present study was to determine if vitamin D intake and status are associated with pre-eclampsia in a country without a vitamin D fortification policy.DesignA case–control study of pregnancies with (case) and without (control) pre-eclampsia was conducted from January to April when UVB is minimal. Maternal and cord blood obtained at delivery were measured for plasma 25-hydroxycholecalciferol (25-OH-D3), 3-epimer of 25-OH-D3(3-epi-25-OH-D3) and 24,25-dihydroxycholecalciferol (24,25-(OH)2D3) by LC–MS/MS and maternal 1,25-dihydroxyvitamin D (1,25-(OH)2D). Diffe

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Cheng, Hui-Fang, Sue-Wan Wang, Ming-Zhi Zhang, James A. McKanna, Richard Breyer, and Raymond C. Harris. "Prostaglandins that increase renin production in response to ACE inhibition are not derived from cyclooxygenase-1." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 283, no. 3 (2002): R638—R646. http://dx.doi.org/10.1152/ajpregu.00150.2002.

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It is well known that nonselective, nonsteroidal anti-inflammatory drugs inhibit renal renin production. Our previous studies indicated that angiotensin-converting enzyme inhibitor (ACEI)-mediated renin increases were absent in rats treated with a cyclooxygenase (COX)-2-selective inhibitor and in COX-2 −/− mice. The current study examined further whether COX-1 is also involved in mediating ACEI-induced renin production. Because renin increases are mediated by cAMP, we also examined whether increased renin is mediated by the prostaglandin E2 receptor EP2 subtype, which is coupled to Gs and incr

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Glukhov, V. P., A. V. Ilyash, V. V. Mitusov, et al. "Relapses of urethral strictures associated with a pelvic ring fracture and osteosynthesis: the features of treatment and prevention." Vestnik Urologii 9, no. 2 (2021): 25–33. http://dx.doi.org/10.21886/2308-6424-2021-9-2-25-33.

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Introduction. Pelvic ring fracture with complex bone fragments displacement is associated with the urethral distraction injury in about 10% of cases. Emergency care for these patients includes the provision of trauma management and urinary diversion followed by delayed urethroplasty.Purpose of the study. To determine the effect of extramedullary osteosynthesis in a pelvic ring fracture on the outcome of treatment in patients with post-traumatic urethral strictures.Materials and methods. The study included 17 patients with post-traumatic urethral strictures associated with pelvic ring fractures

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Liu, Xiang, Siyue Yang, Xingping Zheng, Feilong Dai, Qingrong Yao, and Jiang Wang. "Phase Formation and Magnetic Properties of (Y1−xSmx)Co5 Melt-Spun Ribbons." Metals 14, no. 5 (2024): 562. http://dx.doi.org/10.3390/met14050562.

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Using X-ray diffraction (XRD) and a vibrating sample magnetometer (VSM), the effects of Sm substitution, wheel speed, and annealing temperature on the phase formation and magnetic properties of (Y1−xSmx)Co5 (x = 0.2, 0.3, 0.4, 0.5) melt-spun ribbons were investigated. The results indicate the following: (1) With the increase in Sm substitution, it was found that (Y1−xSmx)Co5 ribbons are entirely composed of the (Y-Sm)Co5 phase with a CaCu5-type structure. Additionally, the coercivity gradually increases, while the remanence and saturation magnetization gradually decrease. (2) As the wheel spee

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Khan, Rizwan Taj, Komal Mumtaz, Basharat Mehmood, et al. "EFFECT OF DIFFERENT HORMONAL CONCENTRATIONS ONIN-VITRO REGENERAT-ION OF RICE (Oryza sativaL.)." Pakistan Journal of Biotechnology 19, no. 02 (2022): 97–102. http://dx.doi.org/10.34016/pjbt.2022.19.2.97.

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The present study was aimed to evaluate the effect of different hormonal concentrations on the in vitro growth and multiplication of rice seeds. The experiment was performed in the tissue culture laboratory, department of biotechnology, UAJ&K Muzaffarabad, Azad Kashmir. Seeds were collected from the local market. Seeds were surface sterilized with different concentrations of Chlorox i. e. (30, 50 and 50 %) and germination percentage was calculated. The maximum (70 %) germination was recorded for seeds treated with 50% chlorox. Whereas minimum germination (37.5%) was recorded for seeds trea

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Rabenstein, L., T. Krumpen, S. Hendricks, C. Koeberle, C. Haas, and J. A. Hoelemann. "A combined approach of remote sensing and airborne electromagnetics to determine the volume of polynya sea ice in the Laptev Sea." Cryosphere Discussions 7, no. 1 (2013): 441–73. http://dx.doi.org/10.5194/tcd-7-441-2013.

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Abstract. A combined interpretation of synthetic aperture radar (SAR) satellite images and helicopter electromagnetic (HEM) sea-ice thickness data has provided an estimate of sea-ice volume formed in Laptev Sea polynyas during the winter of 2007/08. The evolution of the surveyed sea-ice areas, which were formed between late December 2007 and middle April 2008, was tracked using a series of SAR images with a sampling interval of 2–3 days. Approximately 160 km of HEM data recorded in April 2008 provided sea-ice thicknesses along profiles that transected sea-ice varying in age from 1–116 days. Fo

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Rabenstein, L., T. Krumpen, S. Hendricks, C. Koeberle, C. Haas, and J. A. Hoelemann. "A combined approach of remote sensing and airborne electromagnetics to determine the volume of polynya sea ice in the Laptev Sea." Cryosphere 7, no. 3 (2013): 947–59. http://dx.doi.org/10.5194/tc-7-947-2013.

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Abstract. A combined interpretation of synthetic aperture radar (SAR) satellite images and helicopter electromagnetic (HEM) sea-ice thickness data has provided an estimate of sea-ice volume formed in Laptev Sea polynyas during the winter of 2007/08. The evolution of the surveyed sea-ice areas, which were formed between late December 2007 and middle April 2008, was tracked using a series of SAR images with a sampling interval of 2–3 days. Approximately 160 km of HEM data recorded in April 2008 provided sea-ice thicknesses along profiles that transected sea ice varying in age from 1 to 116 days.

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Lang, Brittany, Zachary Yukio Kerr, Samuel R. Walton, et al. "2 The Longitudinal Relationship Between Concussion History, Years of Football Participation, and Alcohol Use Among Former National Football League (NFL) Players: an NFL-LONG Study." Journal of the International Neuropsychological Society 29, s1 (2023): 114–15. http://dx.doi.org/10.1017/s1355617723002060.

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Objective:It has been posited that alcohol use may confound the association between greater concussion history and poorer neurobehavioral functioning. However, while greater alcohol use is positively correlated with neurobehavioral difficulties, the association between alcohol use and concussion history is not well understood. Therefore, this study investigated the cross-sectional and longitudinal associations between cumulative concussion history, years of contact sport participation, and health-related/psychological factors with alcohol use in former professional football players across mult

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Rivera Teran, V., D. Alpizar-Rodriguez, S. Sicsik, et al. "FRI0546 GENDER DIFFERENCES OF RHEUMATIC DISEASES IN MEXICAN POPULATION: DATA FROM THE MEXICAN BIOLOGICS REGISTRY." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 874–75. http://dx.doi.org/10.1136/annrheumdis-2020-eular.6091.

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Background:Most autoimmune diseases are more prevalent in women. Symptom severity, disease progression, response to therapy and overall survival differ between males and females with rheumatic diseases.Objectives:To identify the characteristics of autoimmune diseases presentation and treatment between male and female population using information from the Mexican Adverse Events Registry (BIOBADAMEX).Methods:BIOBADAMEX is a Mexican ongoing cohort that collects the information of patients using biologic and biosimilar drugs since 2016. For this study we included all patients enrolled in the regis

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Steen, R. W. J. "The effect of supplementing silage-based diets with soya bean and fish meals for finishing beef cattle." Animal Science 46, no. 1 (1988): 43–51. http://dx.doi.org/10.1017/s0003356100003093.

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ABSTRACTTwo experiments have been carried out to examine the effects on the intake and performance of finishing beef cattle of supplementing grass silages (perennial ryegrass) of medium and high digestibility (MD and HD respectively) with either extracted soya-bean meal or fish meal. In each experiment, the two silages were supplemented with (1) barley (107 g crude protein (CP) per kg dry matter (DM)), (2) a mixture of barley and soya-bean meal (187 g CP per kg DM) and (3) a mixture of barley and fish meal (182 g CP per kg DM) in a 2 × 3 factorial design. The MD silages were supplemented with

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Lempesi, Evangelia, Marina Karamolegkou, Nikolaos Pandis, and Maria Mavragani. "Maxillary canine impaction in orthodontic patients with and without agenesis: A cross-sectional radiographic study." Angle Orthodontist 84, no. 1 (2013): 11–17. http://dx.doi.org/10.2319/022413-155.1.

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ABSTRACT Objective: To assess potential associations between maxillary canine impaction (MCI) and agenesis status as well as between MCI and gender. Materials and Methods: The records of 182 orthodontic patients with agenesis (excluding the third molars) and 630 orthodontic patients without agenesis were examined. Diagnosis of MCI was based on pretreatment panoramic radiographs. Maxillary canines that had not erupted as a result of physical barrier or deflection in the eruption path at the dental age of at least 12 years were considered impacted. Logistic regression analysis was used to test f

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Alina, Ștefănescu, Florea I. Cristian, Boancă A. Crina, Rădulescu Andrei, and Vițălaru B. Alexandru. "Acute kidney injury in a dog diagnosed with leishmaniasis: case report." Scientific Papers Journal VETERINARY SERIES 66, no. 4 (2023): 20–25. http://dx.doi.org/10.61900/spjvs.2023.04.04.

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A 3 years old, 40.8 kg, intact male American Bully, diagnosed with acute kidney injury in a private clinic in Serbia was referred for hemodialysis therapy. The dog was presented with the following symptoms: lethargy, appetite loss, vomiting, diarrhea, weight loss, dehydration (8 10%, Considerable loss of skin turgor), rectal temperature of 38.8oC and dry mucous membranes. Arterial blood pressure was elevated 218-220 mmHg systolic, using Doppler method. The biochemistry revealed elevated ALT 191 (RR: 10-118 U/L), AMY 1390 (RR: 200-1200 U/L), BUN 94 (RR: 7 25 mg/dL), CREA 3.6 (RR: 0.4-1.2 mg/dL)

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Cooper, Odelia, and Sungjin Kim. "ODP643 Metabolic Effects of Growth Hormone Replacement in Craniopharyngioma and Pituitary Adenoma Patients: Analysis of the Hypopituitary Control and Complications Study (HypoCCS) Database." Journal of the Endocrine Society 6, Supplement_1 (2022): A521. http://dx.doi.org/10.1210/jendso/bvac150.1085.

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Abstract Introduction Craniopharyngioma (CP) is a rare, parasellar tumor associated with metabolic dysfunction and panhypopituitarism. We investigated the impact of growth hormone (GH) replacement on metabolic complications in patients with adult-onset CP or pituitary adenoma (PA) using data collected between 1996 and 2012 in HypoCCS, an open-label, global prospective surveillance study of GH replacement in GH deficiency. Methods GH-treated (≥6 months) vs untreated groups in CP and PA patients were compared using ANOVA or Wilcoxon rank-sum test for continuous variables and chi-square test or F

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Zhang, Yanan, Francesco Avallone, and Simon Watson. "An aeroacoustics-based approach for wind turbine blade damage detection." Journal of Physics: Conference Series 2265, no. 2 (2022): 022088. http://dx.doi.org/10.1088/1742-6596/2265/2/022088.

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Abstract In this work, aimed at the development of an aeroacoustics-based wind turbine blade damage detection approach, the noise scattered from two airfoils with damage at the trailing edge or at the leading edge is investigated. Four trailing edge cracks (with width of 0.2, 0.5, 1.0 and 2.0 mm) and four leading edge erosion configurations (consisting of gouges and delamination) are investigated for a NACA 0018 and a DU96 W180 airfoil. Experiments are carried out under clean and turbulent inflow conditions. Acoustic measurements are performed in an anechoic wind tunnel with a microphone array

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