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1

Capboscq, Alberto Carlos, and Guillermo Andrés Juárez. "Recensiones: Julian of Toledo. Prognosticum futuri saeculi - Foreknowledge of the World to come ; Domingo M. Basso, O.P., Moral Fundamental." Studium. Filosofía y Teología 14, no. 27 (2011): 193–204. https://doi.org/10.53439/stdfyt27.14.2011.193-204.

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Julian of Toledo. Prognosticum futuri saeculi - Foreknowledge of the World to come, translated, edited, and introduced by Tommaso Stancati O.P., Foreword by His Eminence Cardinal Antonio Cañizares Llovera Archbishop of Toledo, Primate of Spain (Ancient Christian Writers 63), New York/Manwah, NJ, The Newmann Press, 2010; 15 + 608 pp. (Alberto Carlos Capboscq) Domingo M. Basso, O.P., Moral Fundamental. Buenos Aires, EDUCA, 2011, 514 pp., ISBN: 978-987-620-187-2. (Guillermo Andrés Juárez)
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2

Dumond, Mark, David Dumond, Cheryl Cook, Brett Duffner, and Julie Laribee. "A Clinical Evaluation of the Correlation and Reprodicibility Of Three Automated Devices For Measurement of Activated Clotting Times." Journal of ExtraCorporeal Technology 22 (1990): 27–29. http://dx.doi.org/10.1051/ject/199022s027.

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The Activated Clotting Time (ACT) assumes an important role in documentation of adequacy of perfusion. Therefore, it is important to document the correlation and reproducibility of automated systems currently available to measure the ACT value. During surgical procedures of 37 patients requiring cardiopulmonary bypass a blood sample was drawn in a single syringe and ACT values obtained using four Hemotec ACTs (T-ACT), four Hemochron ACTs (M-ACT), and two Sonoclot ACTs (S-ACT). Sample points with the mean of two of the three sets of ACTs exceeding 650 were excluded and the values were divided i
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Barr, Emma, Judith Neubauer, and Celine Gelinas. "516 LinkedIn Marketing Strategies to Drive NJ ACTS Regulatory Core Engagement." Journal of Clinical and Translational Science 6, s1 (2022): 106. http://dx.doi.org/10.1017/cts.2022.310.

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OBJECTIVES/GOALS: Our purpose is to promote traffic toward the NJ ACTS Regulatory Cores recently launched website and increase investigator engagement through marketing strategies on LinkedIn. Landscaping to characterize the profiles of researchers on LinkedIn was also completed to estimate the feasibility of engaging with a target population on LinkedIn. METHODS/STUDY POPULATION: Insight gathering was performed to analyze what percentage of researchers possessed a LinkedIn profile and actively used their accounts. A sample population consisting of 284 NJ ACTS members were analyzed to summariz
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Ibragimov, A., and M. Seyidli. "Content of Copper and Molybdenum in Forage Plants of Winter Pastures of the Nakhchevan Autonomous Republic." Bulletin of Science and Practice 10, no. 12 (2024): 385–88. https://doi.org/10.33619/2414-2948/109/48.

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The amount of copper and molybdenum was determined in samples of grass collected from the winter pastures of Bashbashi and Negram. As a result, the norm of copper content (5.3-11.8 mg per 1 kg of air-dried grass) and molybdenum (3.8±0.8-7.8±0.8 mg) was determined. Of the food plants, wormwood contains the most molybdenum, and copper-accumulating plants include wormwood and legumes. Forage plants of the Bashbashinsky and Negramsky winter pastures accumulate sufficient amounts of copper. Its content varies in the grasses of winter pastures of Bashbashinsky from 6.0 mg to 8.3 mg, on average 6.7-7
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5

Sljivo, Armin, Lejla Brigic, Arian Abdulkhaliq, et al. "Echocardiographic Findings of Covid-19 Patients in Canton Sarajevo During the Third Wave of the Covid-19 Pandemic." Materia Socio Medica 35, no. 4 (2023): 290. http://dx.doi.org/10.5455/msm.2023.35.290-294.

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Background: Increasing evidence indicates that COVID-19 may result in cardiac issues in certain individuals, such as myocarditis, arrhythmias, and heart failure. Ongoing research on echocardiographic manifestations is still limited.Objective: To investigate the incidence and patterns of left and right ventricular dysfunction in COVID-19 patients. Methods: This study retrospectively observed COVID-19 patients admitted to the Clinical Center of University of Sarajevo during the third wave, with a particular focus on cardiac evaluations.Results. Our patients, predominantely male 155 (72.4%), with
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Carretero, M. V., and F. de A. F. de Mello. "Produção de latex por clones de seringueira (Hevea spp) no planalto e litoral do Estado de São Paulo." Anais da Escola Superior de Agricultura Luiz de Queiroz 45 (1988): 151–66. http://dx.doi.org/10.1590/s0071-12761988000100011.

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A partir dos dados de produção em volume de látex, extraído de clones de seringueira (Hevea spp.), durante 17 anos no Centro Experimental Theodureto de Camargo (Campinas, região de planalto) e 16 anos na Estação Experimental Vale do Ribeira (Pariquera-Açú, região litorânea), ambos pertencentes ao Instituto Agro_ nômico do Estado de São Paulo, Campinas, foi estudado o comportamento da produção de cada clone. Pelo teste de Tukey foi possível determinar, considerando-se as duas regiões, os melhores clones quanto ao potencial produtivo dado pelas médias de produção. Entre os melhores encontram-se:
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7

Poole, S. G., M. J. Dooley, and D. Rischin. "Calculating carboplatin doses using the 4-variable modification of diet in renal disease (4-v MDRD) estimate of glomerular filtration rate (GFR) in the Calvert formula." Journal of Clinical Oncology 25, no. 18_suppl (2007): 2521. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.2521.

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2521 Background: The dose of carboplatin is usually calculated using the Calvert formula, with various bedside estimates utilized rather than directly measured GFR. The 4-v MDRD equation (Levey AS, et al. Ann Intern Med 2006; 145: 247–254) is now advocated as the routine method of estimating renal function from serum creatinine in all patients. Adoption in clinical practice is occurring despite lack of validation in oncology patients. The aim of this study was to compare carboplatin doses derived from the Calvert formula using measured GFR and the estimates of the 4-v MDRD equation and other e
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8

Coleman, Niamh, and Vivek Subbiah. "Picking needles in a haystack: Exploring rare variants of a pan-cancer target in the RET landscape from 229,453 adult cancer patients." Journal of Clinical Oncology 43, no. 16_suppl (2025): 3150. https://doi.org/10.1200/jco.2025.43.16_suppl.3150.

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3150 Background: Advances in precision oncology have led to the approval of tumor-agnostic therapies, and RET, due to its role as a driver of oncogenesis across multiple tumor types, is increasingly recognized as a pan-cancer target. RET alterations, including mutations and fusions, are relatively rare events, however, potent and selective RET inhibitors such as selpercatinib and pralsetinib have demonstrated remarkable efficacy and changed clinical practice in RET-driven NSCLC, thyroid cancer and other cancers. Here, we present a comprehensive analysis of RET alterations in pan-cancer adult m
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9

Afroz, M., MR Amin, MRU Miah, and MM Hossain. "Incidence of major insect pests on sweet gourd germplasm." Bangladesh Journal of Agricultural Research 44, no. 4 (2020): 621–30. http://dx.doi.org/10.3329/bjar.v44i4.45697.

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Abundance of the major insect pests viz., red pumpkin beetle, epilachna beetle and fruit fly on twelve sweet gourd germplasms namely BD 264, BD 265, BD 266, BD 268, BD 269, BD 274, BD 275, BD 277, BARI Mistikumra 1, BARI Mistikumra 2, Gazipur Local Line and China line was studied in the experimental field of the Department of Entomology, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur, Bangladesh during July 2018 to June 2019. The mean number of red pumpkin was the highest (2.3 adults/ 3 leaves) during 4th week of December and the lowest (0.7 adults/ 3 leaves) during 4th wee
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10

Oleg Kshivets. "Non-small cell lung cancer: 10-year survival after surgery." World Journal of Advanced Research and Reviews 12, no. 2 (2021): 246–60. http://dx.doi.org/10.30574/wjarr.2021.12.2.0586.

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Objective: 10-Year survival (10YS) after radical surgery for non-small cell lung cancer (LC) pa­tients (LCP) (T1-4N0-2M0) was analyzed. Methods: We analyzed data of 768 consecutive LCP (age=57.6±8.3 years; tumor size=4.1±2.4 cm) radically operated (R0) and monitored in 1985-2021 (m=660, f=108; upper lobectomies=277, lower lobectomies=177, middle lobectomies=18, bilobectomies=42, pneumonectomies=254, mediastinal lymph node dissection=768; combined procedures with resection of trachea, carina, atrium, aorta, VCS, vena azygos, pericardium, liver, diaphragm, ribs, esophagus=193; only surgery-S=618
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11

Oleg, Kshivets. "Non-small cell lung cancer: 10-year survival after surgery." World Journal of Advanced Research and Reviews 12, no. 2 (2021): 246–60. https://doi.org/10.5281/zenodo.5716671.

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<strong>Objective:</strong>&nbsp;10-Year survival (10YS) after radical surgery for non-small cell lung cancer (LC) pa&shy;tients (LCP) (T1-4N0-2M0) was analyzed. <strong>Methods:&nbsp;</strong>We analyzed data of 768 consecutive LCP (age=57.6&plusmn;8.3 years; tumor size=4.1&plusmn;2.4 cm) radically operated (R0) and monitored in 1985-2021 (m=660, f=108; upper lobectomies=277, lower lobectomies=177, middle lobectomies=18, bilobectomies=42, pneumonectomies=254, mediastinal lymph node dissection=768; combined procedures with resection of trachea, carina, atrium, aorta, VCS, vena azygos, pericard
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12

B. K. Yadav, Indra Mani, and J. S. Panwar. "Relationship Between Disc Geometry and Draft Requirement." Journal of Agricultural Engineering (India) 43, no. 1 (2006): 49–52. http://dx.doi.org/10.52151/jae2006431.1158.

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A disc is considered as part of shell of a hallow sphere and used as soil working tool with tillage implement. Detailed information about the effect of disc geometry specially disc diameter with varying concavity is not available. A single disc tool carrier was designed to mount and test the performance of disc of different diameter and concavity. A total of nine discs in the diameter range of 510-610 mm and concavity within 51-95 mm were tested under field conditions for their draft requirement and work performance. The results showed that draft increased consistently with increase in diamete
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13

Rodrigues, Alisson Mendes, Fabiana Pereira da Costa, Suellen Lisboa Dias Beltrão, Jucielle Veras Fernandes, Romualdo Rodrigues Menezes, and Gelmires de Araújo Neves. "Development of Eco-Friendly Mortars Produced with Kaolin Processing Waste: Durability Behavior Viewpoint." Sustainability 13, no. 20 (2021): 11395. http://dx.doi.org/10.3390/su132011395.

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This study presents the development of new eco-friendly mortar compositions containing kaolin residues (KR) and assesses their durability behavior. Firstly, the natural and calcinated kaolin residues (600 °C, 650 °C, 700 °C, 750 °C, and 800 °C) were characterized by X-ray diffraction (XRD), differential thermal analysis (DTA), granulometric analysis, and surface area. The kaolin residue calcinated at 800 °C was chosen to be added to new compositions of mortar because it presented the best pozzolanic performance. The aging tests accomplished in internal (Ei) and external (Ee) environments were
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14

Tepper, Stewart J., Hans-Christoph Diener, Messoud Ashina, et al. "Erenumab in chronic migraine with medication overuse." Neurology 92, no. 20 (2019): e2309-e2320. http://dx.doi.org/10.1212/wnl.0000000000007497.

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ObjectiveTo determine the effect of erenumab, a human anti-calcitonin gene-related peptide receptor monoclonal antibody, in patients with chronic migraine and medication overuse.MethodsIn this double-blind, placebo-controlled study, 667 adults with chronic migraine were randomized (3:2:2) to placebo or erenumab (70 or 140 mg), stratified by region and medication overuse status. Data from patients with baseline medication overuse at baseline were used to assess changes in monthly migraine days, acute migraine-specific medication treatment days, and proportion of patients achieving ≥50% reductio
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15

O., Babaiah, Satyanarayana K., Raveendra Reddy P., Krishna Reddy V., and Sreenivasulu Reddy T. "Direct and derivative spectrophotometric method for the determination of nickel(II) with 2,4-dihydroxy benzaldehyde isonicotinoyl hydrazone." Journal of Indian Chemical Society Vol. 83, Mar 2006 (2006): 259–62. https://doi.org/10.5281/zenodo.5835448.

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Department of Chemistry, Sri Krishnadevaraya University, Anantapur-515 003, Andhra Pradesh, India <em>Manuscript received 1 April 2004, revised 27 October 2005, accepted 28 November 2005</em> A simple and sensitive spectrophotometric method has been developed for the determination of nickel(ll) in aqueous medium.The metal ion forms an yellow coloured soluble complex with 2,4-dihydroxy benzaldehyde isonicotinoyl hydrazone (2,4-DHBINH) at pH 6.0 with &lambda;<sub>max</sub> at 400 nm. Beer&#39;s law is obeyed in the range of 0.059-1.17 &mu;g ml-1 of Ni<sup>II.</sup>&nbsp;The molar absorptivity an
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16

Wimalasingham, Akhila Ganeshi, Alfonso Gomez De Liano Lista, Roderick de Bruijn, et al. "Meta-analysis of upfront VEGF targeted therapy prior to nephrectomy in metastatic clear cell renal cancer." Journal of Clinical Oncology 35, no. 6_suppl (2017): 514. http://dx.doi.org/10.1200/jco.2017.35.6_suppl.514.

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514 Background: The safety and efficacy of upfront VEGF targeted, before nephrectomy in metastatic clear cell renal cancer (mCCRC) has not been robustly evaluated. Methods: In this study we performed a meta-analysis of 3 studies (NCT) with an almost identical design and included a single institution experience (which adopted this approach as a standard). Patients with newly diagnosed mCCRC had 12-18 weeks of sunitinib or pazopanib therapy prior to planned cytoreductive nephrectomy (CN). Results: 224 patients were included in this analysis (54% had sunitinib and 46% pazopanib). Overall, 73% had
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17

O., Babaiah, Raveendra Reddy P., Krishna Reddy V., and Sreenivasulu Reddy T. "First order derivative spectrophotometry for simultaneous determination of MoVI and TiIV using 2,4-dihydroxy benzaldehyde isonicotinoyl hydrazone (DHBINH)." Journal of India Chemical Society Vol 81, Aug 2004 (2004): 670–73. https://doi.org/10.5281/zenodo.5830092.

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Department of Chemistry, Sri Krishnadevaraya University, Anantapur-515 003, India <em>Manuscript received 25 March 2003. revised 6 February 2004. accepted 18 March 2004</em> A first order derivative spectrophotometric method is employed for the determination of molybdenum(VI) and simultaneous determination of molybdenum(VI) and titanium(IV). Molybdenum(VI) gives a golden yellow colour with 2,4-dihydroxy benzaldehyde isonicotinoyl hydrazone (DHBINH)&#39; in the pH range 1-3. The first derivative spectrum shows maximum amplitude at 490 nm. Beer&#39;s law is obeyed the range 0.19 to 6.0 &micro;g-
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18

Kamdin, Farzan, Kruti Khemani, and Annamma Varghese. "COVID-19 lockdown impact on physical activity and anxiety levels among physiotherapy practitioners, teaching faculty and students in Mumbai: a cross-sectional web-based e-survey study." International Journal Of Community Medicine And Public Health 8, no. 5 (2021): 2406. http://dx.doi.org/10.18203/2394-6040.ijcmph20211765.

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Background: Coronavirus (COVID-19) has spread rapidly throughout the world leading to an emergency global pandemic. Among the varied affected sections of the population and healthcare, physiotherapy is no exception. To what extent, both the physical activity and anxiety levels have been affected amongst the physiotherapy practitioners, teaching faculty and students is not completely known. Hence, this study was undertaken.Methods: Among a potential 400 participants, 357 responded (response rate=89.25%). Cross-sectional web based open e-survey was sent using google forms via emails and social m
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Matsuyama, Hideyasu, Nobuaki Matsubara, Tomoyuki Taguchi, Takeshi Seto, and Kazuhiro Suzuki. "Post marketing surveillance study of cabazitaxel (CBZ) in Japanese patients with castration resistant prostate cancer (CRPC) in real world settings." Journal of Clinical Oncology 36, no. 6_suppl (2018): 290. http://dx.doi.org/10.1200/jco.2018.36.6_suppl.290.

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290 Background: The study evaluated safety and efficacy of CBZ in Japanese patients (pts) with CRPC in real world settings. Methods: This prospective, observational study targeted all CRPC pts receiving CBZ in daily practice between September 2014 and June 2015. Observation period was 1 year after first dose of CBZ given. Adverse drug reactions (ADRs) were evaluated for safety by CTCAE 4.0. Overall survival (OS), time to treatment failure (TTF) and prostate specific antigen (PSA) response rate (≥30% PSA decrease) were the efficacy endpoints. Two groups, those given 25mg/m2 of CBZ as initial do
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Bauman, Glenn, Mohammed Rashid, Deanna L. Langer, et al. "A prospective provincial registry of PSMA PET CT for recurrent prostate cancer (PREP): Results for 4135 men." Journal of Clinical Oncology 43, no. 5_suppl (2025): 35. https://doi.org/10.1200/jco.2025.43.5_suppl.35.

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35 Background: PREP was initiated in Ontario to provide access and characterize performance of PSMA PET CT among men with recurrent prostate cancer after primary definitive treatment (RP or RT). Methods: Between 03/18 and 09/22, 4135 men were accrued. Men were enrolled and imaged with 18F-DCFPyL at 1 of 6 participating sites within 1 of 6 clinical cohorts. Standardized reports delineated sites of recurrence and post PET management changes. Linkage to provincial databases allowed estimation of overall survival and utilization of salvage radiotherapy after PET. Results: Median follow-up was 1.8
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Han, Molong, Ashok Meghwal, Soon Hock Ng, et al. "Microparticles of High Entropy Alloys Made by Laser-Induced Forward Transfer." Materials 15, no. 22 (2022): 8063. http://dx.doi.org/10.3390/ma15228063.

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The controlled deposition of CoCrFeNiMo0.2 high-entropy alloy (HEA) microparticles was achieved by using laser-induced forward transfer (LIFT). Ultra-short laser pulses of 230 fs of 515 nm wavelength were tightly focused into ∼2.4 μm focal spots on the ∼50-nm thick plasma-sputtered films of CoCrFeNiMo0.2. The morphology of HEA microparticles can be controlled at different fluences. The HEA films were transferred onto glass substrates by magnetron sputtering in a vacuum (10−8 atm) from the thermal spray-coated substrates. The absorption coefficient of CoCrFeNiMo0.2α≈6×105 cm−1 was determined at
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22

Salah alhalbusi, Ghazwan, and A’amal A. H. Al-Saidi. "Enhancing the Ability of The Square Footing to Resist Positive and Negative Eccentric Inclined Loading Using an Inclined Skirt." E3S Web of Conferences 427 (2023): 01020. http://dx.doi.org/10.1051/e3sconf/202342701020.

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Laboratory model tests were performed to investigate the behavior of shallow and inclined skirted foundations placed on sandy soil with R.D%=30 and the extent of the impact of the positive and negative eccentric-inclined loading effect on them. To achieve the experimental tests, it was used a box of (600×600) mm cross-sectional and 600mm in height and a square footing of (50*50) mm and 10 mm in thickness attached to the skirt with Ds=0.5B and various an angle of (10°, 20°, 30°). The results showed that using skirts leads to a significant improvement in load-carrying capacity and decreased sett
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23

K., Hussain Reddy, B. L. Prasad N., S. Reddy T., and Syaji Rao M. "First and second derivative spectrophotometric determination of copper(II) using 2-acetylthiophene-4-phenyl-3-thiosemicarbazone." Journal of Indian Chemical Society Vol. 83, Oct 2006 (2006): 980–83. https://doi.org/10.5281/zenodo.5830840.

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Department of Chemistry, Sri Krishnadevaraya University, Anantapur-515 003, Andhra Pradesh, India Oil Technological Research Institute, INTU, Anamapur-515 001, Andhra Pradesh, India Department of Chemistry, OU PG Center, Mirzapur-502 249 (Medak Dt.), Andhra Pradesh, India <em>Manuscript received 29 November 2005, revised 3 July 2006, accepted&nbsp;6 July 2006</em> The reagent, 2-acetylthlopheoe-4-phenyl-3-thloselllicarbazone (ATPT) has been used for the spectrophotometric determination of copper(ll) in aqueous medium.The reagent gins instense colour reaction with copper(II) in sodium acetate-a
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24

Watanabe, Yasumasa, Alec Houpt, and Sergey Leonov. "Plasma-Assisted Control of Supersonic Flow over a Compression Ramp." Aerospace 6, no. 3 (2019): 35. http://dx.doi.org/10.3390/aerospace6030035.

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This study considers the effect of an electric discharge on the flow structure near a 19.4° compression ramp in Mach-2 supersonic flow. The experiments were conducted in the supersonic wind tunnel SBR-50 at the University of Notre Dame. The stagnation temperature and pressure were varied in a range of 294–600 K and 1–3 bar, respectively, to attain various Reynolds numbers ranging from 5.3 × 105 to 3.4 × 106 based on the distance between the exit of the Mach-2 nozzle and the leading edge of the ramp. Surface pressure measurements, schlieren visualization, discharge voltage and current measureme
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Wibisono Nugraha, Eka Devinta Novi Diana, Frieda, Alfina Rahma, and Prasetyadi Mawardi. "Secondary Syphilis in the Second Trimester Pregnancy : Case Report." Indian Journal of Forensic Medicine & Toxicology 16, no. 1 (2021): 1263–70. http://dx.doi.org/10.37506/ijfmt.v16i1.17670.

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Background: Syphilis is a sexually transmitted disease caused by Treponema pallidum, which is transmitted through sexual contact, blood transfusion and transplacental from an infected mother to the fetus. Syphilis in pregnancy can cause complications including abortion, low birth weight, premature birth, neonatal death or congenital syphilis infection.Case: A 39-year-old woman, 16 weeks pregnant, presented with a complaint of a small lump on the genitals accompanied by red patches on the palms of the hands and feet. Serological tests showed a reactive VDRL of 1:512 and a reactive TPHA of 1:640
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He, S. Y., Y. Q. Yu, G. C. Zhang, and Q. R. Yang. "Effects of Vacuum Pre-Cooling on Quality of Mushroom after Cooling and Storage." Advanced Materials Research 699 (May 2013): 189–93. http://dx.doi.org/10.4028/www.scientific.net/amr.699.189.

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Experiments were conducted to determine if vacuum cooling has an effect on the physical and chemical quality characteristics of mushroom after cooling and storage. Pressure, temperature and mass variations of mushroom were obtained during vacuum cooling. The pressure was decreased from 10000 Pa to 600 Pa within 4 min and then maintained it until the end of vacuum cooling process. Accordingly the temperature of mushroom dropped from initial 25.1 °C to 2.4 °C within 25 min, and the mass loss was 5.3%. Subsequently, vacuum cooled mushroom were stored at 1±0.5°C. and 85-95% of relative humidity fo
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27

Goodman, Rachel S., J. Randall Patrinely, Cosby A. Stone, et al. "Accuracy and Reliability of Chatbot Responses to Physician Questions." JAMA Network Open 6, no. 10 (2023): e2336483. http://dx.doi.org/10.1001/jamanetworkopen.2023.36483.

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ImportanceNatural language processing tools, such as ChatGPT (generative pretrained transformer, hereafter referred to as chatbot), have the potential to radically enhance the accessibility of medical information for health professionals and patients. Assessing the safety and efficacy of these tools in answering physician-generated questions is critical to determining their suitability in clinical settings, facilitating complex decision-making, and optimizing health care efficiency.ObjectiveTo assess the accuracy and comprehensiveness of chatbot-generated responses to physician-developed medic
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28

Sukauichai, Sitthi, Kulthida Maneenil, Archara Supavavej, et al. "EGFR Mutation-positive Lung Cancer in Real-world Treatment Outcomes: A Multicenter Study from Thailand." Asian Pacific Journal of Cancer Care 7, no. 4 (2022): 643–50. http://dx.doi.org/10.31557/apjcc.2022.7.4.643-650.

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Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKI) have been the standard of care as first-line (1L) therapy for patients with advanced EGFR mutated lung cancer since 2009. In Thailand, however, it was not fully introduced to all health care funds until 2020. The purpose of this study was to determine the overall survival (OS) and treatment pattern in the period before EGFR-TKI became universally available to all patients.&#x0D; Methods: This was a retrospective study conducted at 10 medical centers in Thailand. Patients harboring the common mutation (exon 19 de
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29

Nicolaeva, B. K., and A. P. Borisov. "Development of a Software and Hardware Complex for Investigation of the Velocity Vector Field in a Cyclone Separator." Bulletin of Kalashnikov ISTU 21, no. 2 (2018): 204. http://dx.doi.org/10.22213/2413-1172-2018-2-204-210.

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Рассмотрен актуальный вопрос автоматизации и исследования векторного поля скоростей в циклоне-сепараторе с винтовой вставкой. В отличие от циклонов, используемых сейчас на зерноперерабатывающих предприятиях, имеющих эффективность 80 %, циклон-сепаратор с винтовой вставкой позволяет увеличить эффективность очистки до 99,5-99,9 %, что позволяет более эффективно использовать его во взрывоопасном мукомольном производстве. Для выявления эффективных режимов работы и параметров циклона-сепаратора было проведено моделирование векторного поля скоростей в SolidWorks, исследованы тангенциальная, осевая и
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30

Trifilio, S., M. K. Khalid, G. Pennick, et al. "Voriconazole Therapeutic Drug Monitoring: Relationship between Drug Levels and Liver Function Tests." Blood 108, no. 11 (2006): 2950. http://dx.doi.org/10.1182/blood.v108.11.2950.2950.

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Abstract Voriconazole is increasingly being used after HSCT. The hepatic cytochrome P450 isoenzyme 2C19 plays a significant role in voriconazole metabolism. As CYP2C19 exhibits significant genetic polymorphism, some patients metabolize voriconazole poorly resulting in increased plasma drug levels. However, the clinical significance of this is unknown. There is some evidence that toxicity rates are higher in patients with higher voriconazole levels (Boyd et al. Clin Infect Dis2004;39:1241–1244). In a preliminary study of 41 voriconazole levels in 25 patients, we had found that voriconazole leve
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31

Truett, A. P., R. Snyderman, and J. J. Murray. "Stimulation of phosphorylcholine turnover and diacylglycerol production in human polymorphonuclear leukocytes. Novel assay for phosphorylcholine." Biochemical Journal 260, no. 3 (1989): 909–13. http://dx.doi.org/10.1042/bj2600909.

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Receptor-bypassing stimulants of human polymorphonuclear leukocytes (PMNLs), such as ionomycin or phorbol 12-myristate 13-acetate (PMA), generate an increase in diacylglycerol (DAG) which is independent of a phospholipase C specific for phosphatidylinositol 4,5,-bisphosphate (PIP2). Activation of a phospholipase C specific for phosphatidylcholine (PC) has been implicated as a source of DAG in other cells by measuring the release of radiolabelled phosphorylcholine. However, since PMNLs could not be labelled sufficiently with [3H]choline, we developed an h.p.l.c. assay to quantify mass levels of
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32

Hu, Xichun, Jian Zhang, Rujiao Liu, et al. "Phase I study of A166 in patients with HER2-expressing locally advanced or metastatic solid tumors." Journal of Clinical Oncology 39, no. 15_suppl (2021): 1024. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.1024.

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1024 Background: A166 is an antibody-drug conjugate composed of a novel cytotoxic drug (Duo-5, anti-microtubule agent) site-specifically conjugated to an anti-HER2 antibody (transtuzumab) via a stable protease-cleavable valine citrulline linker. In a phase I trial in US patients (pts) with relapsed or refractory advanced solid tumor, A166 had an acceptable toxicity profile and best objective response rate (ORR) of 36% at efficacious dose levels (Yongheng Liu et al. ASCO 2020). Here we report a phase I study of A166 in Chinese pts with locally advanced or metastatic solid tumors (CTR20181301).
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33

Jeong, Ka Yeon, Claudio Pasian, and David Tay. "(125) Response of Six Begonia Species to Different Substrate pH." HortScience 40, no. 4 (2005): 1085C—1085. http://dx.doi.org/10.21273/hortsci.40.4.1085c.

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Substrate pH of soilless media directly affects nutrient availability. Limited information about the effect of substrate pH on growth of begonia species (not cultivated hybrids) was found in the literature. The objective of this study was to evaluate the effect of substrate pH on the growth and quality of six begonia species grown from June to Aug. 2004. The targeted pH ranges (&lt;4.5, 4.5∼5.0, 5.0∼5.5, 5.5∼6.0, 6.0∼6.5, 6.5∼7.0, and over 7.0) of the peat-based substrates were obtained by adding seven different amounts of dolomitic hydrated lime: 0, 1.0, 1.3, 1.6, 2.0, 2.4, and 2.6 kg·m3. Beg
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34

Walsh, Kimberly D., Nader Soltani, David C. Hooker, Robert E. Nurse, and Peter H. Sikkema. "Biologically effective rate of sulfentrazone applied pre-emergence in soybean." Canadian Journal of Plant Science 95, no. 2 (2015): 339–44. http://dx.doi.org/10.4141/cjps-2014-264.

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Walsh, K. D., Soltani, N., Hooker, D. C., Nurse, R. E. and Sikkema, P. H. 2015. Biologically effective rate of sulfentrazone applied pre-emergence in soybean. Can. J. Plant Sci. 95: 339–344. Sulfentrazone is a protoporphyrinogen (PPO)-inhibiting herbicide under evaluation for use in soybean in Ontario, Canada. The primary objective of this study was to determine the dose of sulfentrazone applied pre-emergence (PRE) needed to provide 50 and 90% control of redroot pigweed, common ragweed, common lambsquarters and green foxtail. Seven field trials were conducted over a 3-yr period (2007, 2008 and
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35

Wise, R., T. Gee, G. Marshall, and J. M. Andrews. "Single-Dose Pharmacokinetics and Penetration of BMS 284756 into an Inflammatory Exudate." Antimicrobial Agents and Chemotherapy 46, no. 1 (2002): 242–44. http://dx.doi.org/10.1128/aac.46.1.242-244.2002.

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ABSTRACT The pharmacokinetics of a single dose of BMS 284756 were determined following oral administration of a 600-mg dose to eight healthy male volunteers. Concentrations of the drug were measured in plasma and a cantharidine-induced inflammatory exudate by a microbiological assay. The mean peak concentration in plasma of 10.4 μg/ml (standard deviation [SD], 1.3 μg/ml) was attained at a mean time of 1.2 h (SD, 0.5 h) after the dose. The penetration into the inflammatory exudate was 82% (SD, 15.7%). A mean peak concentration of 7.2 μg/ml (SD, 2.4 μg/ml) was attained in the inflammatory exudat
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36

Akman, A., O. Oram, and P. Aydin. "Optic Disc Measurements with the 78 Diopter Lens, Zeiss 4-Mirror Contact Lens and Computerized Image Analysing System." European Journal of Ophthalmology 8, no. 1 (1998): 22–27. http://dx.doi.org/10.1177/112067219800800106.

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We evaluated the 78 diopter (D) lens and Zeiss 4-mirror lens for the measurement of vertical and horizontal optic disc diameters during slit-lamp biomicroscopy and compared the results with the measurements made with the computerized image analysing system (IMAGEnet 640, Topcon, Japan) in 30 eyes of 30 patients. The 78D lens and Zeiss 4-mirror lens measurements both correlated well with the computerized image analysis measurements (r=0.881 for vertical and r=0.895 for horizontal disc diameter measurements with the 78D lens and r=0.883 for vertical and r=0.891 for horizontal disc diameter measu
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37

Balla, József, György Balla, Viktoria Jeney, György Kakuk, Harry S. Jacob, and Gregory M. Vercellotti. "Ferriporphyrins and endothelium: a 2-edged sword—promotion of oxidation and induction of cytoprotectants." Blood 95, no. 11 (2000): 3442–50. http://dx.doi.org/10.1182/blood.v95.11.3442.011k51_3442_3450.

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Heme arginate infusions blunt the symptoms of patients with acute intermittent porphyria without evidence of the vascular or thrombotic side effects reported for hematin. To provide a rationale for heme arginate's safety, the present study examined the effects of various ferriporphyrins to sensitize human endothelial cells to free radical injury and to induce heme oxygenase and ferritin expression. Heme arginate, unlike hematin, did not amplify oxidant-induced cytotoxicity mediated by hydrogen peroxide (5.3 ± 2.4 versus 62.3 ± 5.3% 51Cr release,P &lt; .0001) or by activated neutrophils (14.4 ±
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38

Vyayzenen, G., R. Dautov, A. Vyayzenen, D. Bolshakov, and N. Prodanov. "Vitamin nutrition of calves." Kormlenie sel'skohozjajstvennyh zhivotnyh i kormoproizvodstvo (Feeding of agricultural animals and feed production), no. 3 (March 1, 2020): 25–36. http://dx.doi.org/10.33920/sel-05-2003-03.

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Experimental studies have shown an increase in productivity, metabolic processes, the effectiveness of the use of nutrients and biologically active substances and the metabolic energy of diets, the health of heifers aged 1–6 months under the conditions of industrial technology of their rearing. Increasing the productivity of heifers is closely related to improving the nutrition system during all periods of rearing with the use of the vitamin complex Vitaminol in diets depending on their age and body weight. The highest effectiveness of rearing young animals has been established when using Vita
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39

Gihring, Katharina Elisabeth, Isaac Tebogo Rampedi, Phillippa Notten, and Phyllis Rumbidzai Kwenda. "Perceptions and acceptability of single-use plastic and alternative food takeaway containers at the University of Johannesburg in South Africa." Journal of Solid Waste Technology and Management 51, no. 2 (2025): 230–40. https://doi.org/10.5276/jswtm/iswmaw/512/2025.230.

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Food outlets at the University of Johannesburg (UJ) mainly use expanded polystyrene (EPS) packaging for takeaway food. This study investigated the awareness levels of consumers (UJ staff and students) about the environmental impact of single-use food packaging mismanagement. It also studied their perceptions and acceptability of alternative food packaging. For data collection, an online questionnaire was sent out via uLink (a student and staff messaging portal at UJ) from the 9th of October 2021 to the 23rd of February 2022. Microsoft Excel and IBM SPSS v 28.0.0 were then used to perform descr
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40

Todd-Brown, K. E. O., J. T. Randerson, W. M. Post, et al. "Causes of variation in soil carbon predictions from CMIP5 Earth system models and comparison with observations." Biogeosciences Discussions 9, no. 10 (2012): 14437–73. http://dx.doi.org/10.5194/bgd-9-14437-2012.

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Abstract. Stocks of soil organic carbon represent a large component of the carbon cycle that may participate in climate change feedbacks, particularly on decadal and century scales. For Earth system models (ESMs), the ability to accurately represent the global distribution of existing soil carbon stocks is a prerequisite for predicting future carbon-climate feedbacks. We compared soil carbon predictions from 16 ESMs to empirical data from the Harmonized World Soil Database (HWSD) and Northern Circumpolar Soil Carbon Database (NCSCD). Model estimates of global soil carbon stocks ranged from 510
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41

Giai, Valentina, Stefania Tamiazzo, Sabrina Leoncino, et al. "Graft Purity and Composition Significantly Impact the Engraftment of Autologous Stem Cell Transplants." Blood 128, no. 22 (2016): 5733. http://dx.doi.org/10.1182/blood.v128.22.5733.5733.

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Abstract Background: Autologous stem cell transplantation (ASCT) has been widely used in the treatment of hematological malignancies over the last two decades. Despite its broad use, some characteristics that might influence engraftment have not been exhaustively investigated, particularly graft purity with respect to contamination by platelets (PLTS) and White Blood Cells (WBC). Here we report collection characteristics and engraftment kinetics of a single Center consecutive series of 510ASCTs. Methods: We retrospectively collected clinical records of patients who underwentleucapheresis proce
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42

Tsao, Bang Hung, Jacob Lawson, James D. Scofield, Clinton Laing, and Jeffery Brown. "3D Thermal Stress Model for SiC Power Modules." Materials Science Forum 600-603 (September 2008): 1227–30. http://dx.doi.org/10.4028/www.scientific.net/msf.600-603.1227.

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Three dimensional models of both single-chip and multiple-chip power sub-modules were generated using ANSYS in order to simulate the effects of various substrate materials, heat fluxes, heat transfer coefficients, and device placement configurations on temperature and thermal stress contours. Alumina, aluminum-nitride, and CVD diamond were compared as substrates. Heat fluxes of 100 to 500 watts/cm2 resulted in SiC device junction temperatures in the range of 350 to 650 K. The predicted maximum operating temperature for a chip, to which 300 watts/cm2 of heat flux was applied, would be 239°C (51
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43

Weltman, Arthur, Cathy J. Pritzlaff, Laurie Wideman, et al. "Exercise-dependent growth hormone release is linked to markers of heightened central adrenergic outflow." Journal of Applied Physiology 89, no. 2 (2000): 629–35. http://dx.doi.org/10.1152/jappl.2000.89.2.629.

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To test the hypothesis that heightened sympathetic outflow precedes and predicts the magnitude of the growth hormone (GH) response to acute exercise (Ex), we studied 10 men [age 26.1 ± 1.7 (SE) yr] six times in randomly assigned order (control and 5 Ex intensities). During exercise, subjects exercised for 30 min (0900–0930) on each occasion at a single intensity: 25 and 75% of the difference between lactate threshold (LT) and rest (0.25LT, 0.75LT), at LT, and at 25 and 75% of the difference between LT and peak (1.25LT, 1.75LT). Mean values for peak plasma epinephrine (Epi), plasma norepinephri
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44

Balla, József, György Balla, Viktoria Jeney, György Kakuk, Harry S. Jacob, and Gregory M. Vercellotti. "Ferriporphyrins and endothelium: a 2-edged sword—promotion of oxidation and induction of cytoprotectants." Blood 95, no. 11 (2000): 3442–50. http://dx.doi.org/10.1182/blood.v95.11.3442.

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Abstract Heme arginate infusions blunt the symptoms of patients with acute intermittent porphyria without evidence of the vascular or thrombotic side effects reported for hematin. To provide a rationale for heme arginate's safety, the present study examined the effects of various ferriporphyrins to sensitize human endothelial cells to free radical injury and to induce heme oxygenase and ferritin expression. Heme arginate, unlike hematin, did not amplify oxidant-induced cytotoxicity mediated by hydrogen peroxide (5.3 ± 2.4 versus 62.3 ± 5.3% 51Cr release,P &amp;lt; .0001) or by activated neutro
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45

Puxeddu, Mariano. "Interaction of B-rich supercritical magmatic fluids with granite: first report of dumortierite in a geothermal field, Larderello, Italy." South Florida Journal of Development 3, no. 3 (2022): 3162–69. http://dx.doi.org/10.46932/sfjdv3n3-009.

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In a peraluminous two-mica monzogranite cored at 4.5 km depth in well Radicondoli 29, dumortierite occurs together with andalusite, Li-rich tourmaline, fluorite and fluorapatite. The average composition is SiO2: 30.9, Al2O3: 58.6, FeO: 0.44, MgO: 0.47, CaO: 0.02, F: 0.15. Dumortierite crystallized from supercritical magmatic fluids at T =520-620°C, P = 100 ± 30 MPa. Synthetic fluid inclusions yielded T = 510 ± 10 MPa, P = 42 ± 3 MPa at 2.9 km depth in well Venelle 2. Al data suggest present day T = 450-550°C, P = 40-80 MPa. The supercritical magmatic fluids were hypersaline brines with ~ 30 wt
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46

Puxeddu, Mariano. "Interaction of B-rich supercritical magmatic fluids with granite: first report of dumortierite in Larderello, Italy." E3S Web of Conferences 98 (2019): 01042. http://dx.doi.org/10.1051/e3sconf/20199801042.

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In a peraluminous two-mica monzogranite cored at 4.5 km depth in well Radicondoli 29, dumortierite occurs together with andalusite, Li-rich tourmaline, fluorite and fluorapatite. The average composition is SiO2: 30.9, Al2O3: 58.6, FeO: 0.44, MgO: 0.47, CaO: 0.02, F: 0.15. Dumortierite crystallized from supercritical magmatic fluids at T =520-620°C, P = 100 ± 30 MPa. Synthetic fluid inclusions yielded T = 510 ± 10°C, P = 42 ±3 MPa at 2.9 km depth in well Venelle 2. All data suggest present-day T = 450-550°C, P = 40-80 MPa. The supercritical magmatic fluids were hypersaline brines with ~ 30 wt %
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47

Sartori Dameto, Larissa, Francisco Carlos Krzyzanowski, Marco Eustáquio de Sá, Adonis Moreira, and Larissa Alexandra Cardoso Moraes. "DESEMPENHO FISIOLÓGICO DE SEMENTES DE CULTIVARES SOJA CONVENCIONAL EM FUNÇÃO DO TAMANHO E TEOR DE UMIDADE NA GERMINAÇÃO." BRAZILIAN JOURNAL OF AGRICULTURE - Revista de Agricultura 98, no. 2 (2023): 119–31. http://dx.doi.org/10.37856/bja.v98i2.4330.

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Quality test protocols for soybean seeds recommend a period of soaking and preconditioning without detailing the size of the seeds to be evaluated, as seeds of different sizes reach different degrees of humidity in each period owing to differences in their initial moisture level and size. Determining the degree of seed moisture during the preconditioning period is important when conducting accelerated aging, tetrazolium, and primary root protrusion tests. The objective of this study was to evaluate the physiological performance of two conventional soybean cultivars (BRS 284 and BRS 511) with t
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48

Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics
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49

Young, Richard A., Sarah Holder, Neelima Kale, Sandra K. Burge, and Kaparaboyna A. Kumar. "Coding Family Medicine Residency Clinic Visits, 99213 or 99214? A Residency Research Network of Texas Study." Family Medicine 51, no. 6 (2019): 477–83. http://dx.doi.org/10.22454/fammed.2019.862757.

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Background and Objectives: The purpose of this study was to characterize Current Procedural Terminology (CPT) coding patterns for professional services in family physician (FP) residency clinics. Methods: Trained assistants directly observed during every other FP-patient encounter in 10 clinics affiliated with eight residencies of the Residency Research Network of Texas. Three investigators later independently coded each visit for the highest code level reasonably allowed. The primary outcome was the number of clinic visits that were actually coded as a CPT 99203/213 that could have been coded
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50

Rome, Sophie, Virginie Lecomte, Emmanuelle Meugnier, et al. "Microarray analyses of SREBP-1a and SREBP-1c target genes identify new regulatory pathways in muscle." Physiological Genomics 34, no. 3 (2008): 327–37. http://dx.doi.org/10.1152/physiolgenomics.90211.2008.

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In this study we have identified the target genes of sterol regulatory element binding protein (SREBP)-1a and SREBP-1c in primary cultures of human skeletal muscle cells, using adenoviral vectors expressing the mature nuclear form of human SREBP-1a or SREBP-1c combined with oligonucleotide microarrays. Overexpression of SREBP-1a led to significant changes in the expression of 1,315 genes (655 upregulated and 660 downregulated), whereas overexpression of SREBP-1c modified the mRNA level of 514 genes (310 upregulated and 204 downregulated). Gene ontology analysis indicated that in human muscle c
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