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1

Eberman, Lindsey E., Elizabeth R. Neil, Sara L. Nottingham, Tricia M. Kasamatsu, and Cailee E. Welch Bacon. "Athletic Trainers' Practice Patterns Regarding Medical Documentation." Journal of Athletic Training 54, no. 7 (2019): 822–30. http://dx.doi.org/10.4085/1062-6050-230-18.

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Context Medical documentation is a required component of patient care in all health care professions. Objective To evaluate athletic trainers' perceived behaviors toward, barriers to, and confidence in their medical documentation. Design Cross-sectional study. Setting Web-based survey. Patients or Other Participants We purchased a list of randomly selected e-mails from the National Athletic Trainers' Association. Of the 9578 participants, 1150 accessed our questionnaire (12.0% access rate), 1053 completed at least 1 portion, and 904 completed the questionnaire in its entirety (85.8% completion
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Sun, Xiao Ting, Qi Zhou, Fei Du, Ming Feng Wu, Shen Fei Tang, and Yan Long Bi. "A Novel Effective Y-Shaped Silicon Stent for Treating Canalicular Laceration." Advanced Materials Research 652-654 (January 2013): 449–53. http://dx.doi.org/10.4028/www.scientific.net/amr.652-654.449.

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Purpose: To introduce the novel effective Y-shaped silicon stent for treating canalicular laceration. Methods: Fifty-four canalicular laceration cases (54 eyes) underwent the lacrimal surgery using the novel Y-shaped silicon stents were collected, and the stents were removed 3 months after surgery. All cases were followed up for 12 months. The operability of stenting and removing the stent were assessed. The data we collected during each follow-up are: stent position and integrity, aesthetic results, the discomfort, the symptom of epiphora, the patency of lacrimal passage, complications, and p
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Schmitz, Randy J., Sandra J. Shultz, and Anh-Dung Nguyen. "Dynamic Valgus Alignment and Functional Strength in Males and Females During Maturation." Journal of Athletic Training 44, no. 1 (2009): 26–32. http://dx.doi.org/10.4085/1062-6050-44.1.26.

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Abstract Context: Sex differences in dynamic measures have been established in physically mature populations. Gaining information on maturation's effect on dynamic performance measures implicated in injury risk may enable us to better design injury prevention programs. Objective: To examine sex differences in dynamic valgus alignment and triple-hop distance measures across maturational stages in males and females. A secondary purpose was to determine if a field test of strength and power predicts dynamic valgus alignment. Design: Cross-sectional study. Setting: Laboratory. Patients or Other Pa
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Rodrigues, André Luiz de Souza, Carla de Castro Sant’Anna, Diego Di Felipe Ávila Alcantara, Amanda Cohen-Paes, Margareth Maria Braun Guimarães Imbiriba, and Rommel Mario Rodriguez Burbano. "Evaluation of Circulating MicroRNAs in Schizophrenia: From Epigenomic Dysregulation to Potential Biomarkers." Psychiatry International 5, no. 4 (2024): 1026–35. https://doi.org/10.3390/psychiatryint5040070.

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To evaluate the expression profile of circulating miRNAs in patients with schizophrenia (hsa-miR-34a, miR-449a, miR-564, miR-432, miR-548d, miR-572, and miR-652) in relation to individual negative controls for the disease. This was an analytical, case-controlled, cross-sectional study, using samples previously collected from patients diagnosed with schizophrenia (N = 650) and a control group (N = 924). Samples were analyzed after RNA extraction and quantification. After making a general comparison between the case and control groups, regardless of gender and other variables, all seven miRNAs s
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Limerova, Valentina Aleksandrovna. "RIVER IN THE WORKS BY M. F. ISTOMIN: ON THE PROBLEM OF MODELING THE IMAGE OF THE NORTH IN THE WORKS OF KOMI WRITERS OF THE XIX CENTURY." Yearbook of Finno-Ugric Studies 15, no. 4 (2021): 654–62. http://dx.doi.org/10.35634/2224-9443-2021-15-4-654-662.

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The works of Mikhail Fedorovich Istomin (1821-1862) are part of the unexplored and, until recently, not included in the history of Komi literature material - essays created by Komi writers of the XIX century in Russian language. Meanwhile, the work of M. Istomin is very representative both in terms of the formation of General regional characteristic of all the literature of the North, and the ways of familiarizing Komi intelligentsia to literary work. The analysis of works of M. Istomin made in this work, allows to judge about actual for the writer-“foreigner” of the XIX century connection to
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Coleman, Niamh, and Vivek Subbiah. "Picking needles in a haystack: Exploring rare variants of a pan-cancer target in the RET landscape from 229,453 adult cancer patients." Journal of Clinical Oncology 43, no. 16_suppl (2025): 3150. https://doi.org/10.1200/jco.2025.43.16_suppl.3150.

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3150 Background: Advances in precision oncology have led to the approval of tumor-agnostic therapies, and RET, due to its role as a driver of oncogenesis across multiple tumor types, is increasingly recognized as a pan-cancer target. RET alterations, including mutations and fusions, are relatively rare events, however, potent and selective RET inhibitors such as selpercatinib and pralsetinib have demonstrated remarkable efficacy and changed clinical practice in RET-driven NSCLC, thyroid cancer and other cancers. Here, we present a comprehensive analysis of RET alterations in pan-cancer adult m
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de Bruijne, J., J. Bergmann, C. Weegink, et al. "941 JTK-652 IS A NOVEL HCV ENTRY INHIBITOR: RESULTS OF A PHASE 1 STUDY EVALUATING SAFETY, TOLERABILITY AND ANTIVIRAL ACTIVITY IN CHRONIC HEPATITIS C PATIENTS." Journal of Hepatology 50 (April 2009): S342. http://dx.doi.org/10.1016/s0168-8278(09)60943-0.

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Panina, Tatiana Igorevna. "BELIEFS AND PROHIBITIONS RELATED TO SLEEPING AND DREAMS IN THE UDMURT TRADITIONAL CULTURE." Yearbook of Finno-Ugric Studies 14, no. 4 (2020): 642–50. http://dx.doi.org/10.35634/2224-9443-2020-14-4-642-650.

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The article analyzes Udmurt traditional beliefs and rules that regulate human behavior before going to bed, during a sleep and after waking up. The regulations are shaped by the perception of a sleep as the liminal state and as a surprising combination of space and time in which boundaries between this world and the other world are blurred. Compliance with the regulations is supposed to guarantee safety: it can protect the sleeper from the lurking danger during and after a sleep, or in case if the dream foreshadows the upcoming negative changes in life. The main apotropaic measures used before
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Lin, Z. Q., W. H. Hendershot, P. H. Schuepp, G. G. Kennedy, and P. Dutilleul. "Total elements in forest soils affected by acid deposition in southern Quebec." Canadian Journal of Soil Science 76, no. 2 (1996): 165–71. http://dx.doi.org/10.4141/cjss96-023.

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Major and trace elements (Al, As, Ba, Ca, Cd Co, Cr Cs, Cu Eu Fe, Hf, K, La, Lu, Mg, Mn, Na, Ni, Pb, Rb, Sb, Sc, Si, Sm, Sr, Ta, Tb, Th, Ti, U, V, Yb and Zn) in forest soils from three acid-deposition-affected locations in southern Quebec were investigated. Total element concentrations in the surface layer (0–20 cm) of the Podzolic soils were mostly well within the range of element concentrations in Podzols reported worldwide but showed higher mean values for most elements. The mean concentrations of elements (except Zn, at 124 μg g−1) were also generally comparable to the respective elemental
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Masraf, Hannah, Temesgen Azemeraw, Meseret Molla, et al. "Excess mortality among people with podoconiosis: secondary analysis of two Ethiopian cohorts." Transactions of The Royal Society of Tropical Medicine and Hygiene 114, no. 12 (2020): 1035–37. http://dx.doi.org/10.1093/trstmh/traa150.

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Abstract Background While morbidity attributable to podoconiosis is relatively well studied, its pattern of mortality has not been established. Methods We compared the age-standardised mortality ratios (SMRs) of two datasets from northern Ethiopia: podoconiosis patients enrolled in a 1-y trial and a Health and Demographic Surveillance System cohort. Results The annual crude mortality rate per 1000 population for podoconiosis patients was 28.7 (95% confidence interval [CI] 17.3 to 44.8; n=663) while that of the general population was 2.8 (95% CI 2.3 to 3.4; n=44 095). The overall SMR for the st
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Prosekov, Alexander, Olga Altshuler, and Marina Kurbanova. "Quality and Safety of Game Meat from the Biocenosis of the Beloosipovo Mercury Deposit." Food Processing: Techniques and Technology 51, no. 4 (2022): 654–63. http://dx.doi.org/10.21603/2074-9414-2021-4-654-663.

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Introduction. Mercury contamination is one of the most common environmental problems. The research objective was to study the qualitative composition and physicochemical properties of raw game meat obtained from the area near the Beloosipovo mercury deposit in order to define any possible contamination w ith xenobiotics.
 Study objects and methods. The research featured rib eye muscle tissue and soft flesh of elks shot on the hunting farms of the Kemerovo Region aka Kuzbass.
 Results and discussion. A complex set of experiments revealed the chemical composition of elk muscle tissue a
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Prosekov, Alexander, Olga Altshuler, and Marina Kurbanova. "Quality and Safety of Game Meat from the Biocenosis of the Beloosipovo Mercury Deposit." Food Processing: Techniques and Technology 51, no. 4 (2022): 654–63. http://dx.doi.org/10.21603/2074-9414-2021-4-654-663.

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Introduction. Mercury contamination is one of the most common environmental problems. The research objective was to study the qualitative composition and physicochemical properties of raw game meat obtained from the area near the Beloosipovo mercury deposit in order to define any possible contamination w ith xenobiotics.
 Study objects and methods. The research featured rib eye muscle tissue and soft flesh of elks shot on the hunting farms of the Kemerovo Region aka Kuzbass.
 Results and discussion. A complex set of experiments revealed the chemical composition of elk muscle tissue a
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Sadikov, A. T. "Study of productivity and yield indicators of cotton varieties and lines when grown in the conditions of Central Tajikistan." Agrarian science 1, no. 1 (2025): 100–105. https://doi.org/10.32634/0869-8155-2025-390-01-100-105.

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The article presents long-term data on the study of the productivity of cotton varieties and lines in the conditions of Central Tajikistan. In all samples, the number of boxes ranged from 12.6 to 20.4 pcs/plant. This indicator varies along the lines in the range of 9.4–21.8 pcs/plant, which is significantly higher than the standard variety Ziroatkor 64 (9.4 pcs/plant) — up to 12.4 pcs/plant. With a maximum value (17.0–20.4 pcs/plant) of this feature, the varieties Farovon 20, Dusti IZ, Yage 110 and Dangara 30 distinguished themselves with a deviation from the standard by 7.6–11.0 pcs /plant. T
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Kutluk, M. Tezer, and Akif Yeşilipek. "Pediatric Cancer Registry in Turkey 2009-2018 (TPOG & TPHD)." Journal of Clinical Oncology 37, no. 15_suppl (2019): e21510-e21510. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e21510.

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e21510 Background: In Children and adolescents aged 0-14, each year more than 200.000 new cancer cases are expected at global level. For the planning and implementation of an effective pediatric cancer control program, pediatric cancer registries are essential. The long term survival rates have been improved to 85% in high income countries, however it is still less than this in LMICs. This work presents the most updated results of the pediatric cancer registry in Turkey. Methods: Turkish Pediatric Oncology Group and Turkish Pediatric Hematology Association has established the Pediatric Cancer
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Iaria, Roberta, Paolo Vescovi, Pierpaolo De Francesco, and Ilaria Giovannacci. "Laser Photobiomodulation: What Are the Ideal Parameters for Each Type of Laser Used in Dental Practice to Promote Fibroblast Proliferation and Differentiation? A Systematic Review." Life 15, no. 6 (2025): 853. https://doi.org/10.3390/life15060853.

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Laser photobiomodulation (LPMB) is a non-invasive therapy that relies on the use of low-power lasers. The literature supports the positive effect of LPBM on tissue regeneration, since it reduces the timing of the inflammatory phase, promoting the proliferative phase of the process. From a purely clinical point of view, the breadth of lasers currently available for dental use makes it difficult to identify unambiguous parameters that can guarantee the best regenerative effect. Therefore, the aim of the present systematic review is to identify the best irradiation parameters for each type of den
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Gorinova, Natalia Vasilievna. "KOMI FEMALE DRAMA: SOME ASPECTS OF STUDYING THE QUESTION." Yearbook of Finno-Ugric Studies 13, no. 4 (2019): 643–52. http://dx.doi.org/10.35634/2224-9443-2019-13-4-643-652.

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The beginning of the 21st century opened a new page in the development of Komi literature connected with the activity of female authors earlier unprecedented on a dramatic field. In the 2000s Nina Kuratova, Elena Kozlova and Nina Obrezkova addressed dramaturgic genres. By this time they had already been popular writers. Having addressed a dramaturgic genre, new to itself, each writer introduced organic features in a palette of dramaturgic poetics, enriching and updating national culture. We devoted this work to research the specifics of Komi female dramatic art. Gender approach and method of t
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Vorontsov, Vladimir Stepanovich, Alexander Valentinovich Martynenko, Olga Viktorovna Orlova, and Yuri Petrovich Shabaev. "PROBLEMS OF PUBLIC PERCEPTION OF MIGRATION BY THE POPULATION OF THE FINNO-UGRIC REPUBLICS OF RUSSIA (BASED ON MATERIALS FROM MARI EL, MORDOVIA, KOMI, UDMURTIA)." Yearbook of Finno-Ugric Studies 13, no. 4 (2019): 653–63. http://dx.doi.org/10.35634/2224-9443-2019-13-4-653-663.

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The article is an analysis of the results of sociological surveys conducted by its authors in Mari El, Mordovia, Komi, Udmurtia in the fall of 2018.The study was conducted according to the methodology of the Ethnological Monitoring and Early Warning Conflict Network of the Institute of Ethnology and Anthropology of the Russian Academy of Sciences and was aimed at identifying and assessing conflict and integration, the potential of the local population in the field of migration relations. On the whole, these polls revealed a rather high degree of tolerance of the residents of these republics to
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Morozova, Irina Vasilyevna. "FINNISH AMERICAN IDENTITY AND STRATEGIES FOR ITS DETERMINATION IN FINNISH AMERICAN CONTEMPORARY LITERATURE." Yearbook of Finno-Ugric Studies 15, no. 4 (2021): 642–53. http://dx.doi.org/10.35634/2224-9443-2021-15-4-642-653.

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The article focuses on one of the pressing problems of modern humanitarian knowledge - the problem of self-identification of hybrid cultures, in particular, the culture of the Finnish Americans. The ethnic diversity of the United States leads to a constant intersection of various cultures, giving rise to the uniqueness of contemporary American literary life. National, cultural, personal identity associated with the revision of the traditions that were assimilated in their diaspora acts as the main problem of multiculturalism - the ideology of plurality and diversity. Self-identification strate
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Menétrey, P., R. Walther, T. Zimmermann, K. J. Willam, and P. E. Regan. "Simulation of Punching Failure in Reinforced-Concrete Structures." Journal of Structural Engineering 123, no. 5 (1997): 652–59. http://dx.doi.org/10.1061/(asce)0733-9445(1997)123:5(652).

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Ray, Sujit K., and Murty K. S. Madugula. "Discussion of “Transmission Towers: Design of Cold‐Formed Angles” by Edwin H. Gaylord and Gene M. Wilhoite (August, 1985, Vol. 111, No. 8)." Journal of Structural Engineering 113, no. 3 (1987): 652–53. http://dx.doi.org/10.1061/(asce)0733-9445(1987)113:3(652).

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Melnikova, Olga Mikhailovna. "UDMURT CORRESPONDENTS OF ARCHAEOLOGIST O.N. BADER." Yearbook of Finno-Ugric Studies 16, no. 4 (2022): 656–66. http://dx.doi.org/10.35634/2224-9443-2022-16-4-656-666.

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The article is devoted to a little-studied period in the history of archaeological research on the territory of Udmurtia in the post-war years, as reflected in letters addressed to the famous archaeologist Otto Nikolayevich Bader. O. N. Bader worked at the Perm (Molotov) University from the second half of the 1940s until 1954, he formed a scientific archaeological school. Together with his students, he engaged in the archaeological study of the vast Ural-Volga region, including the territory of Udmurtia. O. N. Bader maintained contacts with many scientific, educational and museum organizations
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Chen, Yung-Chun, Zhe-Rong Zheng, Chen-Yu Wang, and Wen-Cheng Chao. "Impact of Early Fluid Balance on 1-Year Mortality in Critically Ill Patients With Cancer: A Retrospective Study in Central Taiwan." Cancer Control 27, no. 3 (2020): 107327482092073. http://dx.doi.org/10.1177/1073274820920733.

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A positive fluid balance has been found to be deleterious in critically ill patients; however, the impact of early fluid balance, particularly on long-term outcomes, in critically ill patients with cancer remains unclear. We performed this retrospective study at a tertiary-care referral hospital with 1500 beds and 6 intensive care units (ICUs) in central Taiwan, and 942 patients with cancer admitted to ICUs during 2013 to 2016 were enrolled. The primary outcome was 1-year mortality. Cancer-related data were obtained from the cancer registry, and data during ICU admissions were retrieved from t
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Leardi, Riccardo. "Design-Expert 6.0, available from Stat-Ease, Inc., 2021 E. Hennepin Avenue, Ste 480, Minneapolis, MN 55413-2726, USA (E-mail: info@statease.com, Telephone: +1-612-378-9449, Fax: +1-612-378-2152), Price: $995 for a single-user licence. For further information of current prices:." Journal of Chemometrics 17, no. 10 (2003): 569–70. http://dx.doi.org/10.1002/cem.820.

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Janne, P. A., L. Paz-Ares Rodriguez, M. Gottfried, et al. "Randomized phase II trial of cisplatin/gemcitabine with or without LY293111, a multiple eicosonaid pathway modulator, in patients with chemotherapy naïve advanced non-small cell lung carcinoma." Journal of Clinical Oncology 24, no. 18_suppl (2006): 7024. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.7024.

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7024 Background: The eicosanoid pathway is altered in NSCLC. Pharmacological activators of peroxisome proliferator-activated receptor-gamma (PPARγ) have been shown to inhibit lung tumors in vitro. LY293111 inhibits the eicosanoid pathway, is a PPARγ agonist and modulates adipophilin and adiponectin expression levels in vitro. LY293111 is well tolerated and can be administered with cisplatin/gemcitabine. A randomized phase II study in NSCLC was undertaken. Methods: Pts with stage IIIB/IV NSCLC were randomized to two doses of LY293111 (200 mg BID (Arm A) or 600 mg BID (Arm B) or placebo (Arm C)
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Farhad-Mollashahi, Leila, Zohreh Dalirsani, Marieh Honarmand, Saeedeh Salimi, and Soudeh Shahabi Nezhad. "Salivary Atopy Biomarkers in Patients with Geographic Tongue." European Journal of General Dentistry 10, no. 03 (2021): 135–38. http://dx.doi.org/10.1055/s-0041-1736375.

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Abstract Objectives Geographic tongue is the mucositis of the dorsal surface of the tongue with no definite etiology, although it may be associated with atopic conditions. In this study, the salivary immunoglobulin E (IgE) and eosinophilic cationic protein (ECP) levels were assessed in patients with geographic tongue to examine the relationship between this condition and allergy-related biomarkers. Materials and Methods In this case-control study, unstimulated saliva was collected from 45 geographic tongue patients and 45 controls, and the salivary IgE and ECP levels were assessed. The data we
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Vene, Nina, Barbara Salobir, Miran Šebeštjen, Mišo Šabovic, Irena Keber, and Borut Jug. "Prognostic impact of haemostatic derangements in chronic heart failure." Thrombosis and Haemostasis 102, no. 08 (2009): 314–20. http://dx.doi.org/10.1160/th08-11-0721.

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SummaryHeart failure is characterised by activation of haemostasis. We sought to explore the prognostic impact of deranged haemostasis in chronic heart failure. In stable, optimally managed outpatients with chronic heart failure, baseline levels of prothrombin fragment F1+2, D-dimer, and tPA and PAI-1 antigens were determined. Clinical follow-up was obtained and the rate of events (heart failure related deaths or hospitalisations) was recorded. We included 195 patients [32.3% female, NYHA class II (66.2%) or III (33.8%), mean age 71 years]. During a median follow up of 693 (interquartile range
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Yang, Fengyuan, Chenxi Yang, Chao Jin, et al. "Pore Structure, Hardened Performance and Sandwich Wallboard Application of Construction and Demolition Waste Residue Soil Recycled Foamed Concrete." Sustainability 16, no. 6 (2024): 2308. http://dx.doi.org/10.3390/su16062308.

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Construction and demolition waste residue soil (CDWRS) recycled foamed concretes were prepared by introducing the original CDWRS into modified binders. Pore structure, hardened performance, and sandwich wallboard application were also investigated. The results indicated that 51 kg/m3 of water glass and 7.5 kg/m3 of gypsum could significantly increase the strength and generate a slight influence on the thermal insulation performance of CDWRS recycled foamed concrete. The largest enhancing rate of 28-day compressive strength at a density of 600 kg/m3 could reach 205.5%. Foamed concrete with 1126
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Escher, Felicitas, Mario Kasner, Uwe Kühl, et al. "New Echocardiographic Findings Correlate with Intramyocardial Inflammation in Endomyocardial Biopsies of Patients with Acute Myocarditis and Inflammatory Cardiomyopathy." Mediators of Inflammation 2013 (2013): 1–9. http://dx.doi.org/10.1155/2013/875420.

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Background. The diagnosis of acute myocarditis (AMC) and inflammatory cardiomyopathy (DCMi) can be difficult. Speckle tracking echocardiography with accurate assessments of regional contractility could have an outstanding importance for the diagnosis.Methods and Results.N=25patients with clinically diagnosed AMC who underwent endomyocardial biopsies (EMBs) were studied prospectively. Speckle tracking imaging was examined at the beginning and during a mean follow-up period of 6.2 months. In the acute phase patients had markedly decreased left ventricular (LV) systolic function (mean LV ejection
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Faigenbaum, Avery D., Jie Kang, Michael DiFiore, et al. "A Comparison of Warm-Up Effects on Maximal Aerobic Exercise Performance in Children." International Journal of Environmental Research and Public Health 19, no. 21 (2022): 14122. http://dx.doi.org/10.3390/ijerph192114122.

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The aim of this study was to compare the warm-up effects of treadmill walking (TW) with a dynamic (DY) bodyweight warm-up on maximal aerobic exercise performance in children. Sixteen children (10.9 ± 1.5 vrs) were tested for peak oxygen uptake (VO2 peak) on 2 nonconsecutive days following different 6 min warm-up protocols. TW consisted of walking on a motor-driven treadmill at 2.2 mph and 0% grade whereas the DY warm-up consisted of 9 body weight movements including dynamic stretches, lunges, and jumps. Maximal heart rate was significantly higher following DY than TW (193.9 ± 6.2 vs. 191.6 ± 6
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Mysula, Yu I. "СТРУКТУРА КОПІНГ-ПОВЕДІНКИ У ХВОРИХ ІЗ ПЕРВИННИМ ЕПІЗОДОМ БІПОЛЯРНОГО АФЕКТИВНОГО РОЗЛАДУ". Здобутки клінічної і експериментальної медицини, № 1 (5 травня 2020): 136–42. http://dx.doi.org/10.11603/1811-2471.2020.v.i1.10725.

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Проблема біполярного афективного розладу (БАР) є однією з найактуальніших у сучасній психіатрії.
 Мета – дослідити особливості копінг-поведінки хворих із первинним епізодом біполярного афективного розладу з урахуванням гендерного фактора і клінічного варіанту дебюту БАР.
 Матеріал і методи. Проаналізовано особливості копінг-поведінки у 153 хворих із первинним епізодом БАР з використанням опитувальника «Способи долаючої поведінки» S. Folkman і R. Lazarus в адаптації Т. Л. Крюкової.
 Результати. Встановлено, що при депресивному варіанті первинного епізоду переважають стратегії вте
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Batiha, Gaber El-Saber, Amany Magdy Beshbishy, Azirwan Guswanto, et al. "Phytochemical Characterization and Chemotherapeutic Potential of Cinnamomum verum Extracts on the Multiplication of Protozoan Parasites In Vitro and In Vivo." Molecules 25, no. 4 (2020): 996. http://dx.doi.org/10.3390/molecules25040996.

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Cinnamomum verum is a commonly used herbal plant that has several documented properties against various diseases. The existing study evaluated the inhibitory effect of acetonic extract of C. verum (AECV) and ethyl acetate extract of C. verum (EAECV) against piroplasm parasites in vitro and in vivo. The drug-exposure viability assay was tested on Madin-Darby bovine kidney (MDBK), mouse embryonic fibroblast (NIH/3T3) and human foreskin fibroblast (HFF) cells. Qualitative phytochemical estimation revealed that AECV and EAECV containing multiple bioactive constituents namely alkaloids, tannins, sa
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Piya, Milan K., Ritesh Chimoriya, William Yu, et al. "Improvement in Eating Disorder Risk and Psychological Health in People with Class 3 Obesity: Effects of a Multidisciplinary Weight Management Program." Nutrients 13, no. 5 (2021): 1425. http://dx.doi.org/10.3390/nu13051425.

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This study aimed to evaluate the risk of eating disorders, psychological distress, and health-related quality of life (HRQoL) in people with class 3 obesity (body mass index (BMI) ≥ 40 kg/m2), and the effect of multidisciplinary weight management over 12 months. This retrospective cohort study included all adults with class 3 obesity who enrolled in a weight management program from March 2018 to December 2019. Questionnaires included the Eating Disorder Examination Questionnaire Short (EDE-QS), Kessler Psychological Distress Scale (K10), and 36-Item Short Form Survey (SF-36) for HRQoL. Physica
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Aydin, Esat, Handan Alay, Sinan Yilmaz, Fatma Can, and Safa Guney. "Borderline, Narcissistic, Obsessive-Compulsive and Schizoid Personality Disorder Beliefs and Their Effects on Anxiety and Depression Levels in Inpatients with Covid-19." Psychiatry and Behavioral Sciences 12, no. 3 (2022): 134. http://dx.doi.org/10.5455/pbs.20211223064116.

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Aim/Background: Mental-health problems among coronavirus disease 2019 (COVID-19) inpatients is an underinvestigated issue. The study reported herein was conducted to assess obsessive-compulsive, borderline, schizoid and narcissistic personality disorder beliefs and the influence of these dysfunctional beliefs on the anxiety and depression levels of COVID-19 inpatients. Methods: A total of 75 COVID-19 inpatients were recruited for the study. Their anxiety and depression levels were evaluated using Hospital Anxiety and Depression Scale, and the aforementioned personality disorder beliefs were ev
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Nagra, D., K. Bechman, M. Russell, et al. "AB0442 RETROSPECTIVE ANALYSIS ON JAK INHIBITORS AT SINGLE CENTRE IN THE UK." Annals of the Rheumatic Diseases 82, Suppl 1 (2023): 1409.2–1410. http://dx.doi.org/10.1136/annrheumdis-2023-eular.2535.

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BackgroundThere are limited real world data on the use of JAK inhibitors (JAKi). In 2022, the EMA suggested that JAKi should only be used if alternative therapies are not available in patients over 65 years, smokers or in those with cardiovascular or cancer risk factors.ObjectivesWe conducted a retrospective study to describe the demographics, duration of therapy and adverse events profile of patients prescribed JAKi.MethodsBaseline data including age, gender, smoking status, ethnicity, co-morbidities, cardiovascular risk factors, rheumatic diagnosis, concomitant csDMARD use and prior biologic
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35

Foucher, Yohann, Marie-Cécile Fournier, Christophe Legendre, et al. "Comparison of machine perfusion versus cold storage in kidney transplant recipients from expanded criteria donors: a cohort-based study." Nephrology Dialysis Transplantation 35, no. 6 (2019): 1051–59. http://dx.doi.org/10.1093/ndt/gfz175.

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Abstract Background Most studies comparing the efficacy of hypothermic machine perfusion (HMP) versus static cold storage (SCS) are based on short-term outcomes. We aimed to better evaluate the mid-term impact of HMP in patients receiving expanded criteria donor (ECD) kidneys. Methods The analyses were based on the French Données Informatisées et VAlidées en Transplantation (DIVAT) observational cohort. Patients aged ≥45 years transplanted for the first or second times from an ECD donor since 2010 were studied. Our study reported the graft and/or patient survivals and the incidence of acute re
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Lukyanov, M. M., S. Yu Martsevich, A. A. Pulin, et al. "Dynamics of age characteristics and prevalence of concomitant cardiovascular and non-sardiovascular diseases in patients hospitalized with COVID-19 during epidemic wave: data from TARGET-VIP registry." Cardiovascular Therapy and Prevention 20, no. 8 (2022): 3106. http://dx.doi.org/10.15829/1728-8800-2021-3106.

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Aim. According to hospital-based registry, to evaluate the age characteristics and prevalence of concomitant cardiovascular and non-сardiovascular diseases in patients hospitalized with COVID-19 during epidemic wave.Material and methods. The TARGET-VIP register included 1130 patients aged 57,5+12,8 years (men, 51,2%) hospitalized at the Pirogov National Medical and Surgical Center from April 6, 2020 to June 22, 2020 with COVID-19. Cardiovascular diseases (CVDs) were diagnosed in 51,6% of patients, non-сardiovascular chronic diseases — in 48,6%, while CVDs and/or non-сardiovascular chronic dise
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Teh, Swee H., Robert Li, Teresa Lin, et al. "Update analysis: Clinical outcomes following regionalization of gastric cancer care in a U.S. integrated health care system." Journal of Clinical Oncology 40, no. 4_suppl (2022): 265. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.265.

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265 Background: The role of laparoscopic gastrectomy and D2 lymphadenectomy is not yet fully defined in patients treated with modern perioperative chemotherapy. In 2016, Kaiser Permanente Northern California regionalized gastric cancer care, introducing a regional comprehensive multidisciplinary care team, standardizing staging and chemotherapy, and implementing laparoscopic gastrectomy and D2 lymphadenectomy for eligible patients with curative-intent surgery. We previously reported a retrospective cohort study comparing treatments and outcomes before and after regionalization, including 2-yea
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Heiser, Clemens, J. Ulrich Sommer, Benedikt Hofauer, et al. "Bilateral vs Unilateral Hypoglossal Nerve Stimulation in Patients With Obstructive Sleep Apnea." OTO Open 6, no. 3 (2022): 2473974X2211097. http://dx.doi.org/10.1177/2473974x221109794.

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Objective Unilateral hypoglossal nerve stimulation (uniHNS) is an effective treatment for obstructive sleep apnea. Bilateral hypoglossal nerve stimulation (biHNS) is a novel therapeutic option and a different approach to hypoglossal nerve stimulation. The aim of this study was to analyze the clinical outcome of the first 10 biHNS cases vs the first 10 uniHNS cases ever implanted. Study Design Prospective data analysis. Setting International multicenter comparative clinical trial. Methods The first 10 patients in 2020 who received a biHNS device (Genio System; Nyxoah) and the first 10 patients
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Gómez, E., S. Carrocera, S. Uzbekova, et al. "Protein in culture and endogenous lipid interact with embryonic stages in vitro to alter calf birthweight after embryo vitrification and warming." Reproduction, Fertility and Development 29, no. 10 (2017): 1932. http://dx.doi.org/10.1071/rd16213.

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Short-term protein removal in vitro improves long-term blastocyst competence to survive vitrification. We investigated the mechanisms and effects underlying protein removal. Day-6 morulae and early blastocysts were cultured individually with and without protein for 24 h. Development and lipid content were analysed in expanded blastocysts derived from morulae (M-XB) and from early blastocysts (EB-XB). Expression of genes involved in lipid metabolism, stress responses and apoptosis was analysed in fresh and vitrified–warmed M-XB produced with and without protein. Pregnancy rates, birth rates and
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Mazerkina, N. A., S. K. Gorelyshev, O. G. Zheludkova, S. S. Ozerov, G. L. Kobiakov, and B. V. Kholodov. "Results of growth hormone substitution therapy in children with brain tumours." Problems of Endocrinology 59, no. 2 (2013): 19–25. http://dx.doi.org/10.14341/probl201359219-25.

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Aim of the study. To estimate the effectiveness and safety of substitution therapy with growth hormone (GH) in children with various brain tumours. Materials and methods. The study involved 68 patients admitted to N.N. Burdenko Institute of Neurosurgery between 2001 and 2011 including 35 ones with craniopharyngioma, 18 with medulloblastoma, and 15 with germ cell tumours (GCT) in the chiasmosellar region. All patients suffered growth hormone insufficiency and received GH replacement therapy. Their antropometric characteristics (height and growth rate) and IGF-1 levels were measured before, 6 an
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Li, Cheng-Zhi, Yu-Juan Lin, and Xiao-Zhang Yu. "Transcriptome Analysis of Cyanide-Treated Rice Seedlings: Insights into Gene Functional Classifications." Life 12, no. 11 (2022): 1701. http://dx.doi.org/10.3390/life12111701.

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Cyanide (CN−) pollution in agricultural systems can affect crop production. However, no data are available to describe the full picture of the responsive metabolic mechanisms of genes with known functions related to exogenous KCN exposure. In this study, we examined the transcriptome in rice seedlings exposed to potassium cyanide (KCN) using an Agilent 4×44K rice microarray to clarify the relationship between the differentially expressed genes (DEGs) and their function classifications. The number of DEGs (up-regulated genes/down-regulated genes) was 322/626 and 640/948 in the shoots and roots
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Clarke, A. M., S. Lukacova, R. H. Dahlrot, et al. "P11.32.A GLIOBLASTOMA NOMOGRAM: PREDICTING THE LOCATION OF FIRST PROGRESSION AFTER LONG-COURSE CHEMORADIOTHERAPY BASED ON A NATIONAL COHORT." Neuro-Oncology 25, Supplement_2 (2023): ii80. http://dx.doi.org/10.1093/neuonc/noad137.266.

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Abstract BACKGROUND Glioblastoma (GBM) is known for its high local failure rate, as well as its migration, leading to these possible locations of disease progression: 1. Local-only; lesion of progression is connected to the initial tumour location 2. Non-local; lesion of progression is not connected to the initial tumour location 3. Combined; both local-only and non-local progression lesions are present An upfront prediction of progression location could potentially be used to select patients for differential treatment strategies. The aim of this retrospective national study was therefore to p
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Ferrara, Cinzia, Gabriella Sglavo, Ilaria Morra, Gabriele Saccone, Costantino Di Carlo, and Giuseppe Bifulco. "Impact of COVID-19 on termination of pregnancy." Perinatal Journal 30, no. 1 (2022): 61–65. http://dx.doi.org/10.2399/prn.22.0301013.

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Objective: To evaluate the impact of COVID-19 pandemic on termination of pregnancy. Methods: This was a retrospective study aimed to assess the impact of COVID-19 pandemic on termination of pregnancy in a single center in Italy. Consecutive data on pregnant women who requested induced termination of pregnancy (I-TOP) from February 2018 to December 2021 were included in a dedicated database. The data were divided into two groups according to the COVID-19 outbreak. Women who requested I-TOP from February 2018 to January 2020 were included into the group ‘before COVID-19 pandemic’. Women who requ
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Balman, Şölen, Eric M. Schlegel, and Patrick Godon. "Characterizing the Advective Hot Flows of Nova-like Cataclysmic Variables in the X-Rays: The Case of BZ Cam and V592 Cas." Astrophysical Journal 932, no. 1 (2022): 33. http://dx.doi.org/10.3847/1538-4357/ac6616.

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Abstract We present a joint spectral analysis of ROSAT PSPC, Swift X-ray Telescope, and Nuclear Spectroscopic Telescope Array Focal Plane Module A/B (FPMA/B) data of the nova-like (NL) cataclysmic variables (CVs) BZ Cam and V592 Cas in the 0.1–78.0 keV band. Plasma models of collisional equilibrium fail to model the 6.0–7.0 iron line complex and continuum with χ ν 2 larger than 2.0. Our results show nonequilibrium ionization (NEI) conditions in the X-ray plasma with temperatures of 8.2–9.4 keV and 10.0–12.9 keV for BZ Cam and V592 Cas, respectively. The centroids of He-like and H-like iron ion
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Zhang, Shuheng, Hanguo Zeng, Wei Ji, et al. "Non-Destructive Testing of Alfalfa Seed Vigor Based on Multispectral Imaging Technology." Sensors 22, no. 7 (2022): 2760. http://dx.doi.org/10.3390/s22072760.

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Seed vigor is an important index to evaluate seed quality in plant species. How to evaluate seed vigor quickly and accurately has always been a serious problem in the seed research field. As a new physical testing method, multispectral technology has many advantages such as high sensitivity and accuracy, nondestructive and rapid application having advantageous prospects in seed quality evaluation. In this study, the morphological and spectral information of 19 wavelengths (365, 405, 430, 450, 470, 490, 515, 540, 570, 590, 630, 645, 660, 690, 780, 850, 880, 940, 970 nm) of alfalfa seeds with di
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Jones, Gareth T., Linda E. Dean, Ejaz Pathan, Rosemary J. Hollick, and Gary J. Macfarlane. "Real-world evidence of TNF inhibition in axial spondyloarthritis: can we generalise the results from clinical trials?" Annals of the Rheumatic Diseases 79, no. 7 (2020): 914–19. http://dx.doi.org/10.1136/annrheumdis-2019-216841.

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Management guidelines assume that results from clinical trials can be generalised, although seldom is data available to test this assumption. We aimed to determine the proportion of patients commencing tumour necrosis factor inhibition (TNFi) who would have been eligible for relevant clinical trials, and whether treatment response differs between these groups and the trials themselves. The British Society for Rheumatology Biologics Register for Ankylosing Spondylitis (BSRBR-AS) recruited a real-world cohort of TNFi-naïve spondyloarthritis patients with data collection from clinical records and
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Friedland, H. David, Tanya O'Neal, Donald Biek, et al. "CANVAS 1 and 2: Analysis of Clinical Response at Day 3 in Two Phase 3 Trials of Ceftaroline Fosamil versus Vancomycin plus Aztreonam in Treatment of Acute Bacterial Skin and Skin Structure Infections." Antimicrobial Agents and Chemotherapy 56, no. 5 (2012): 2231–36. http://dx.doi.org/10.1128/aac.05738-11.

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ABSTRACTScientific and regulatory interest in assessing clinical endpoints after 48 to 72 h of treatment for acute bacterial skin and skin structure infections (ABSSSI) has increased. Historical, pre-antibiotic-era data suggest that a treatment effect relative to untreated controls can be discerned in this time interval. Ceftaroline fosamil, a broad-spectrum bactericidal cephalosporin with activity against Gram-positive organisms, including methicillin-resistantStaphylococcus aureus(MRSA), and Gram-negative organisms was efficacious in two phase 3 trials of complicated skin infections (CANVAS
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Murayama, Anju, Sae Kamamoto, Hiroaki Saito, et al. "Characteristics and Distribution of Scholarship Donations From Pharmaceutical Companies to Japanese Healthcare Institutions in 2017: A Cross-sectional Analysis." International Journal of Health Policy and Management 12 (August 21, 2023): 7621. http://dx.doi.org/10.34172/ijhpm.2023.7621.

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Background: Financial relationships between healthcare institutions and pharmaceutical companies can lead to conflicts of interest (COIs), potentially compromising patients’ care. In Japan, scholarship donations, unique type of payments made to healthcare institutions and their subunits by pharmaceutical industries without restricting their use including non-educational or research purpose, may often have implicit promotional purposes. However, detailed information about these payments remains scarce. Methods: This study employed a cross-sectional design to analyse the extent and distribution
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Sticchi, Alessandro, Dario Grassini, Francesco Gallo, et al. "Gender-Specific Outcomes in TAVI with Self-Expandable Valves: Insights from a Large Real-World Registry." Journal of Clinical Medicine 14, no. 9 (2025): 3144. https://doi.org/10.3390/jcm14093144.

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Background/Objectives: Aortic stenosis (AS) is the most prevalent valvular heart disease in developed countries and imposes an increasing burden on aging populations. Although transcatheter aortic valve implantation (TAVI) has transformed the treatment of severe AS, current guidelines do not differentiate management based on gender. This study aimed to investigate gender-based differences in procedural complications and one-year clinical outcomes in patients treated with next-generation self-expandable TAVI devices. Methods: This retrospective, multicenter international registry included 3862
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Dune, Kingdom K., Seth U. Wadike, and Chiamaka M. Onyeji. "Bioremediation of Crude-Oil-Contaminated Soil Using Oil Palm Frond (Leaf)." Saudi Journal of Engineering and Technology 10, no. 03 (2025): 85–92. https://doi.org/10.36348/sjet.2025.v10i03.006.

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Crude oil spillage is a major problem in Nigeria as it basically affects soils, plants grown on the soil, and the environment at large. The need to remediate crude-oil-contaminated soil to its original state is of utmost importance. The potential of oil palm frond (leaf) to remediate crude-oil-contaminated soil was investigated in this study. The soil samples were analyzed before and after contamination, during bioremediation process and after the treatment process by determining the pH, moisture content and total organic carbon (TOC) parameters of the soil sample each week for a period of fou
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