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1

Martín-Campos, Jesús, Sheila Ruiz-Nogales, Daiana Ibarretxe, et al. "Polygenic Markers in Patients Diagnosed of Autosomal Dominant Hypercholesterolemia in Catalonia: Distribution of Weighted LDL-c-Raising SNP Scores and Refinement of Variant Selection." Biomedicines 8, no. 9 (2020): 353. http://dx.doi.org/10.3390/biomedicines8090353.

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Familial hypercholesterolemia (FH) is associated with mutations in the low-density lipoprotein (LDL) receptor (LDLR), apolipoprotein B (APOB), and proprotein convertase subtilisin/kexin 9 (PCSK9) genes. A pathological variant has not been identified in 30–70% of clinically diagnosed FH patients, and a burden of LDL cholesterol (LDL-c)-raising alleles has been hypothesized as a potential cause of hypercholesterolemia in these patients. Our aim was to study the distribution of weighted LDL-c-raising single-nucleotide polymorphism (SNP) scores (weighted gene scores or wGS) in a population recruit
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Kahn, R., A. Kalali, U. Gustafsson, and S. Nyberg. "Efficacy and tolerability of quetiapine XR 400/600/800mg/day in acute schizophrenia: a post-hoc analysis of data from two pooled randomised studies." European Psychiatry 26, S2 (2011): 1411. http://dx.doi.org/10.1016/s0924-9338(11)73116-9.

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IntroductionData from two, identically designed, placebo-controlled, randomised, double-blind clinical trials (D1444C00132+D1444C00133) for once-daily extended-release quetiapine fumarate (QTP-XR) were pooled and analysed.ObjectiveEvaluate dose response, efficacy and safety for QTP-XR in schizophrenia.MethodsPost-hoc analysis of data from patients receiving QTP-XR 400, 600, 800 mg/day or placebo. Endpoints: least squares means (LSM) change from baseline to Day 42 in PANSS total and positive and negative subscale scores. No corrections for multiplicity were performed. Adverse events (AEs) were
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Saleh, Ramadan, Essam Nada, Ahmed F. Hamed, and Wesam M. Hussien. "Epidemiologic Trends of Viral Skin Infections in Egypt: A Cross-Sectional Hospital-Based Study." Dermatology Research and Practice 2019 (March 27, 2019): 1–4. http://dx.doi.org/10.1155/2019/5469726.

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Viral skin infections (VSIs) were ranked among the top 50 prevalent diseases in 2010. The objective of this study was to determine the epidemiologic features of VSIs in patients attending a dermatology clinic in Egypt from June 2010 to May 2011. Patient’s residence, occupation, housing data, and family history of similar conditions were recorded. Categorical data were recorded as frequencies and percentages and were compared by Chi square test. P value < 0.05 was significant. Diagnosis of VSIs was made in 1000/20322 (4.9%) patients. Out of the 1000 patients with VSIs, 580 (58.0%) were resid
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Chatelet, Valerie, Veronique Fremeaux-Bacchi, Maxence Ficheux, Thierry Lobbedez, and Bruno Hurault-Deligny. "Efficacy of Eculizumab in a Plasmatherapy-Dependent Patient with Atypical Hemolytic Uremic Syndrome with C3 Mutation Following Plasmatherapy Withdrawal." Blood 112, no. 11 (2008): 4579. http://dx.doi.org/10.1182/blood.v112.11.4579.4579.

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Abstract Atypical hemolytic uremic syndrome (aHUS) is a rare microangiopathic hemolytic anemia characterized by chronic intravascular hemolysis, consumptive thrombocytopenia, microvascular glomerular thrombosis and acute renal failure. Atypical HUS develops as the result of unregulated complement activation either through genetic abnormalities in one or more complement proteins or more rarely the development of autoantibodies to complement factor H. Complement dysregulation has been shown to cause cause subendothelium exposure and activation of platelets resulting in a chronic proinflammatory
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Lu, Chang Wei, Szu Han Wu, Hung Hsiang Lin, et al. "Optimization of Operating Conditions for an SOFC Stack." Key Engineering Materials 656-657 (July 2015): 119–23. http://dx.doi.org/10.4028/www.scientific.net/kem.656-657.119.

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Performance testing for a single-cell solid oxide fuel cell (SOFC) stack is carried out to optimize its operating conditions. In this study, the Taguchi method is employed to effectively define the test matrix. The single-cell stack is composed of a 10x10 cm2 commercial anode-supported cell, metallic interconnects, current collectors, and glass-ceramic sealant. The major parameters for the experiments include: flow rates of fuel (hydrogen) and oxidant (air) gases, and temperatures. The target indices are the electrical power output, electrical efficiency, and fuel utilization. The fuel flow ra
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Phinney, L. C., J. L. Duggan, G. Lapicki, F. U. Naab, K. Hossain, and F. D. McDaniel. "Thorium and uranium M-shell x-ray production by 0.4–4.0 MeV protons and 0.4–6.0 MeV helium ions." Journal of Physics B: Atomic, Molecular and Optical Physics 42, no. 8 (2009): 085202. http://dx.doi.org/10.1088/0953-4075/42/8/085202.

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7

Kubošová, Andrea, Miroslav Karlík, Petr Haušild, and J. Prahl. "Fracture Behaviour of Fe3Al and FeAl Type Iron Aluminides." Materials Science Forum 567-568 (December 2007): 349–52. http://dx.doi.org/10.4028/www.scientific.net/msf.567-568.349.

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Fracture behaviour of two intermetallic alloys based on FeAl and Fe3Al was studied. On the alloys Fe-40Al-1C (at%) and Fe-29.5Al-2.3Cr-0.63Zr-0.2C (at%) (FA06Z), a basic characterization, the fracture toughness tests and fractographic analysis were carried out. Tensile tests and fracture toughness tests were performed at 20, 200, 400 and 600°C. The fracture toughness values range from 26 MPa.m1/2 at 20°C to 42 MPa.m1/2 at 400°C. In addition, Jintegral dependence on a obtained by potential method was measured. The fractographic analysis showed that samples fractured at 20, 200 and 400°C in the
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8

Yannakopoulos, A. L., A. S. Tserveni-Gousi, and G. Zervas. "Effect of dietary copper sulphate on the performance of growing Japanese quail." Journal of Agricultural Science 115, no. 2 (1990): 291–93. http://dx.doi.org/10.1017/s0021859600075262.

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SUMMARYThe effect of 200, 400 and 600 mg dietary copper sulphate/kg was studied in 64 Japanese quail (Coturnix coturnix japonica) in 1987. The results indicated that addition of 200 or 400 mg/kg to conventional diets of quail 7–42 days old significantly increased (P < 0·05) body weight gain and significantly decreased (P < 0·05) feed intake. There were significant (P < 0·05) increases in carcass, breast and leg weights in some cases; the first two characters had the highest values in the quail fed the diet containing 200 mg Cu/kg. The addition of 600 mg Cu/kg to the diet had an advers
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Roncatto, Eduardo, Arthur Arrobas Martins Barroso, Juliana Calegarim, Felipe Ridolfo Lucio, and Paulo Fernando Adami. "Control period and economic threshold level of glyphosate tolerant weeds in 2.4-D resistant soybean." Australian Journal of Crop Science, no. 15(02):2021 (February 3, 2021): 297–304. http://dx.doi.org/10.21475/ajcs.21.15.02.p3085.

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Weed densities, species, costs of control, crop value and interference periods should be considered for weed management. With this regard, three experiments were carried out to evaluate weed control periods and weed density in a new soybean cultivar. In ths first trial, control efficacy was measured by visual phytotoxicity of four weed species I. hederifolia, E. heterophylla, Conyza spp. and R. brasiliensis using four different herbicides with two doses each: glyphosate (720 and 1,440 g ea ha-1), 2.4-D (670 and 1,340 g ea ha-1), glufosinate (400 and 600 g ea ha-1) and glyphosate + 2.4-D (410 +
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10

Frystyk, J., H. Gronbaek, C. Skjaerbaek, and A. Flyvbjerg. "Effect of hyperthyroidism on circulating levels of free and total IGF-I and IGFBPs in rats." American Journal of Physiology-Endocrinology and Metabolism 269, no. 5 (1995): E840—E845. http://dx.doi.org/10.1152/ajpendo.1995.269.5.e840.

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Thyroid hormones are suggested to have a permissive role in growth hormone (GH) and insulin-like growth factor I (IGF-I) action and a specific effect on plasma levels of some of the GH-independent IGF binding proteins (IGFBPs). We have investigated the effect of thyroxine (T4) administration on circulating levels of free and total (extractable) IGF-I and IGFBPs in 8-wk-old rats treated with 0, 200, 400, and 600 micrograms/kg T4, respectively. Serum free IGF-I was determined by an ultrafiltration method, serum total IGF-I after acid-ethanol extraction, and serum IGFBPs using Western ligand blot
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Silva, Laura Carvalho da, and Cynthia Jurkiewicz Kunigk. "Efeito do pH na sobrevivência de Bifidobacterium animalis em matriz de fruta." Brazilian Journal of Food Research 10, no. 4 (2019): 118. http://dx.doi.org/10.3895/rebrapa.v10n4.11388.

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Alimentos probióticos que possam ser consumidos por pessoas com intolerância a produtos lácteos estão em crescente demanda. Para colaborar com o desenvolvimento de alimentos probióticos à base de frutas, este estudo teve por objetivo avaliar a sobrevivência de Bifidobacteium animalis em matriz de ameixa com diferentes valores de pH (3,5, 4,0, 5,0, 6,0, e 7,0) durante 42 dias de armazenamento em refrigeração. A matriz de ameixa foi produzida com ameixa seca, xarope de glicose e frutose, sacarose, e pectina e apresentou atividade de água de 0,91, com a textura semelhante a uma geleia. O pH foi a
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12

Grassi, Paolo, Giuseppe Procopio, Raffaele Ratta, et al. "Does dose modification affect efficacy of first-line pazopanib in metastatic renal cell carcinoma?" Journal of Clinical Oncology 35, no. 6_suppl (2017): 512. http://dx.doi.org/10.1200/jco.2017.35.6_suppl.512.

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512 Background: Pazopanib is a standard treatment for metastatic renal cell carcinoma (mRCC) and 800 mg/day is considered the optimal dose for mRCC patients (pts). However, some pts require a dose reduction due to toxicity. It remains unclear whether reduced-dose pazopanib is as effective as the standard dose in achieving a response. Methods: We retrospectively evaluated treatment duration, objective response rate (ORR), progression-free survival (PFS), and discontinuation rate in consecutive pts with mRCC treated with first-line pazopanib between 2011 and 2016 at the Istituto Nazionale Tumori
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13

Henry, Paul H., and Frank A. Blazich. "Influence of Gibberellins4 + 7 on Germination of Fraser Fir." Journal of Environmental Horticulture 6, no. 3 (1988): 93–96. http://dx.doi.org/10.24266/0738-2898-6.3.93.

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Seeds of Fraser fir [Abies fraseri (Pursh) Poir.] were soaked in solutions of gibberellins4+7 (GA4+7) at concentrations of 0, 400, 500, 600, 700, 800, 900, and 1000 ppm. Following treatment, seeds were germinated in the presence and absence of light at 9/15 hr thermoperiods of 30°/20°C (86°/68°F) and 20°/10°C (68°/50°F). At 30°/20°C (86°/68°F), 42-day germination of seeds maintained in darkness was significantly increased at GA4+7 concentrations of 500 and 600 ppm. Stimulation was not noted for illuminated seeds at 30°/20°C (86°/68°F) or for seeds germinated at 20°/10°C (68°/50°F).
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Liu, Yanhan, Cun Liu, Keying An, Xiaowei Gong, and Zhaofei Xia. "Effect of Dietary Clostridium butyricum Supplementation on Growth Performance, Intestinal Barrier Function, Immune Function, and Microbiota Diversity of Pekin Ducks." Animals 11, no. 9 (2021): 2514. http://dx.doi.org/10.3390/ani11092514.

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Clostridium butyricum (C. butyricum) is increasingly being used to test the promotion of the gut health of animals. However, the modes of action for such applications for waterfowl remain unclear. Thus, we investigated whether or not intestinal barrier function, immune-related gene expression, and the diversity of the intestinal microbiota in Pekin ducks varied under C. butyricum supplementation. A total of 500 ducks were randomly assigned into five treatments supplemented with basal diets containing: either 0 (group Control), 200 (group CB200), 400 (group CB400) and 600 (group CB600) mg/kg C.
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15

Alekberova, Z., R. Goloeva, M. Cherkasova, and A. Lila. "AB0477 OVARIAN RESERVE IN PATIENTS WITH RHEUMATIC DISEASES." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1536.2–1537. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3465.

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Background:Access to assays of circulating anti-Mullerian hormone (AMH) levels has opened a new page in the assessment of ovarian function and fertility in various diseases, including rheumatic diseases (RDs). The definition of AMH as a marker of ovarian reserve significantly simplified its interpretation as well as measuring the contribution of the disease itself to the patients’ infertility.Objectives:To evaluate the effects of the disease and it’s treatment on serum AMH levels for Behcet’s disease (BD), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic scleroderma
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Oliveira, R. L., M. A. A. F. Barbosa, U. Cecato, R. C. Matos, A. Rodrigues, and Marina Santiago. "Carbohydrate and protein fractions of mombaça grass under different cutting intervals and nitrogen levels." Biotehnologija u stocarstvu 20, no. 3-4 (2004): 163–67. http://dx.doi.org/10.2298/bah0404163o.

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The objective of the experiment was to evaluate the influence of nitrogen fertilization on cutting intervals on the nitrogen and carbohydrate fractions of Momba?a grass (Pannicum maximum Jacq. cv. Momba?a). The treatments were: 0; 200; 400 and 600 Kg of N/ha and cutting intervals of 35 42; and 49 days. It was used ANOVA and linear regression for the statistical analysis. Significant effect of the nitrogen fertilization and the cutting intervals on the quality composition and on had been observed the protein and carbohydrates fractions. The nitrogen fertilization provided to greeters concentrat
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Agudo-Padrón, A. Ignacio. "Inventario sistemático revisado y actualizado de los moluscos marinos ocurrentes en el Estado de Santa Catarina, Brasil." Revista Brasileira de Gestão Ambiental e Sustentabilidade 2, no. 2 (2015): 59. http://dx.doi.org/10.21438/rbgas.020206.

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Producto de 19 años completos de investigaciones de campo, examen de especímenes depositados em colecciones de museos y estudios referenciales paralelos, el inventário malacológico sistemático marino del Estado de Santa Catarina, Región Subtropical Central Sur del Brasil, es finalmente presentado, comportando un total de 671 espécies e subespécies confirmadas (11 Polyplacophora, 400 Gastropoda, 10 Scaphopoda, 226 Bivalvia y 24 Cephalopoda), distribuídas en 365 gêneros e 152 famílias, correspondientes al 42% del total estimado para el Brasil en general. De estas apenas dos son contempladas por
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Calderano, Arele Arlindo, Ricardo Vianna Nunes, Ramalho José Barbosa Rodrigueiro, and Ricardo Andrade César. "REPLACEMENT OF CHOLINE CHLORIDE BY A VEGETAL SOURCE OF CHOLINE IN DIETS FOR BROILERS." Ciência Animal Brasileira 16, no. 1 (2015): 37–44. http://dx.doi.org/10.1590/1089-6891v16i127404.

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The objective of this study was to evaluate the use of a vegetal source of choline as a replacement of choline chloride in the diet for broilers from one to 21 and 22 to 42 days of age. In the first experiment, we used 1500 Cobb male broilers at one day of age, distributed in a completely randomized design with ten treatments, five repetitions and 30 birds per experimental unit. In the second experiment, we used 1000 Cobb male broiler at 22 days of age, distributed in a completely randomized design with ten treatments, five repetitions and 20 birds per experimental unit. The treatments consist
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Qin, Shukui, Stephen Lam Chan, Wattana Sukeepaisarnjaroen, et al. "A phase II study of the efficacy and safety of the MET inhibitor capmatinib (INC280) in patients with advanced hepatocellular carcinoma." Therapeutic Advances in Medical Oncology 11 (January 2019): 175883591988900. http://dx.doi.org/10.1177/1758835919889001.

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Background: The objectives of this phase II study were to determine the clinical activity of the MET tyrosine kinase inhibitor capmatinib (INC280) in patients with MET-dysregulated advanced hepatocellular carcinoma (HCC) and to assess the safety, pharmacokinetics, and correlation of biomarkers with the response. Methods: This phase II, open-label, single-arm study evaluated twice daily (BID) oral capmatinib in a dose-determining stage, utilizing a Bayesian Logistic Regression Model (BLRM) subject to Escalation with Overdose Control criteria, safety, pharmacokinetics, and pharmacodynamic inform
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Sridhar, T. M., A. Kishen, S. Shanmugaraj, et al. "Biomineralization Studies in Age Induced Human Teeth." Key Engineering Materials 361-363 (November 2007): 893–96. http://dx.doi.org/10.4028/www.scientific.net/kem.361-363.893.

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Human teeth has “structure” and yet is mostly treated as material. Differentiation between material and structure is crucial to understand complex biological material such as human dentine. The aim of the present work is to determine the bioceramic gradient phases of the crystal structure of the teeth across the crown and root region with age. Around 50 samples of teeth of different age groups were collected, decontaminated and sintered at 400, 600 and 800°C. After removal of the enamel the root and crown regions were machined and characterized for their vibrational states by FTIR investigatio
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Daver, Naval, Daniel A. Pollyea, Karen W. L. Yee, et al. "Preliminary Results from a Phase Ib Study Evaluating BCL-2 Inhibitor Venetoclax in Combination with MEK Inhibitor Cobimetinib or MDM2 Inhibitor Idasanutlin in Patients with Relapsed or Refractory (R/R) AML." Blood 130, Suppl_1 (2017): 813. http://dx.doi.org/10.1182/blood.v130.suppl_1.813.813.

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Abstract Introduction: Effective treatment options for patients (pts) with R/R AML are limited and novel therapies are needed. Previous pre-clinical data have shown that venetoclax (VEN) plus cobimetinib (cobi) or idasanutlin (idasa) may be synergistic. MEK and MDM2 inhibition have been shown to down-regulate MCL-1, overcoming a resistance pathway to BCL-2 inhibition in AML (Han, ASH 2016; Pan, ASH 2014). We report preliminary results from a dose-escalation study evaluating VEN plus cobi or idasa in pts with R/R AML. This is the first study evaluating novel-novel oral combinations with VEN in
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Manegold, C., J. Vansteenkiste, F. Cardenal, et al. "Randomized phase II study of three doses of the integrin inhibitor cilengitide versus docetaxel as second-line treatment for patients (pts) with stage IV non-small cell lung cancer (NSCLC)." Journal of Clinical Oncology 27, no. 15_suppl (2009): 8014. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.8014.

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8014 Background: Cilengitide (EMD 121974) is the most advanced compound in clinical development of a new class of oncology drugs, the integrin inhibitors. Integrins (heterodimeric transmembrane receptors) play key roles in cell interactions. Cilengitide selectively inhibits the cell-surface integrins αVβ3 and αVβ5 on activated endothelial cells during angiogenesis and on tumor cells. Methods: Multicenter, open-label, randomized, phase II study in 140 pts with relapsed stage IV NSCLC. Pts received 1 of 3 cilengitide doses (240 [n=35], 400 [n=35], or 600 [n=36] mg/m2) twice weekly or docetaxel 7
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Mamun, MAA, SA Islam, MS Islam, AJ Mridha, and MA Saleque. "Site-Specific Nutrient Management for Irrigated Rice in South Central Region of Bangladesh." Bangladesh Agronomy Journal 20, no. 2 (2018): 1–9. http://dx.doi.org/10.3329/baj.v20i2.37082.

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A site-specific nutrient management (SSNM) field trial was conducted for irrigated rice using five fertilizer treatments: i) omission of N, ii) omission of P, iii) omission of K, iv) NPK and v) farmers’ practice (FP). Substantial variation in the native N, P, and K supply was found among farmers’ fields. The indigenous soil K produced 4.5 to 5.0 t ha-1 but native P and N gave only rice yield of 3.5 to 4.0 t ha-1. The highest grain yield (6.0 to 7.5 t ha-1) was obtained from balanced fertilization, followed by FP (4.0 to 5.0 t ha-1).The optimal grain yield at Faridpur was obtained by using N, P
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Djuric, Slavko, Midhat Omerovic, Sasa Brankov, Ejub Dzaferovic, and Petko Stanojevic. "Experimental examination of sulphur dioxide separation from mixture of gas in dry procedure with the aid of calcium carbonate." Thermal Science 15, no. 1 (2011): 115–24. http://dx.doi.org/10.2298/tsci100525062d.

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This paper refers to an experiment of SO2 absorption to the particles of sorbent CaCO3, the mass of sample was 100 g with fractional composition of 500-700?m and 1100-1300?m. During the experiment the temperature varied from 200 and 400?C. The aim of this experiment described in this paper, is to examine the influence of lower reaction temperature, the size of sorbent particles and reaction time to the degree of SO2 absorption and determining the degree of CaCO3 sorbent utilization. The results show that at the reaction temperature of approximately 200?C and average diameter of sorbent particl
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BOLTON, LANCE F., and JOSEPH F. FRANK. "Defining the Growth/No-Growth Interface for Listeria monocytogenes in Mexican-Style Cheese Based on Salt, pH, and Moisture Content." Journal of Food Protection 62, no. 6 (1999): 601–9. http://dx.doi.org/10.4315/0362-028x-62.6.601.

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The objective of this study was to define combinations of pH, salt, and moisture that produce growth, stasis, or inactivation of Listeria monocytogenes in Mexican-style cheese. A soft, directly acidified, rennet-coagulated, fresh cheese similar to Mexican-style cheese was produced. The cheese was subsequently altered in composition as required by the experimental protocol. A factorial design with four moisture contents (42, 50, 55, and 60%), four salt concentrations (2.0, 4.0, 6.0, and 8.0% wt/wt), six pH levels (5.0, 5.25, 5.50, 5.75, 6.0, and 6.5), and three replications was used. Observatio
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Freer, M., H. Dove, A. Axelsen, JR Donnelly, and GT McKinney. "Responses to supplements by weaned lambs grazing mature pasture or eating hay in yards." Australian Journal of Experimental Agriculture 25, no. 2 (1985): 289. http://dx.doi.org/10.1071/ea9850289.

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Weaned crossbred lambs grazing mature pasture in summer at stocking rates of 14, 28 or 42 lambs/ha were supplemented for 60 days with 0, 400, 600 or 800 g/day of either sunflower meal or a 1:1 mixture of sunflower meal and oats. Mean daily gains in fasted weight without and with supplement were - 51 and 62 g, respectively, with no significant difference between the three feeding levels. Greasy wool production increased from 4.7 g/day without supplement to 9.9 g/day at the 600 or 800 g level but the composition of the supplement had no effect. Stocking rate had no effect on animal performance.
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D.L., Tri Retno, Nana Mulyana, Nurhasni Nurhasni, and Uswatun Hasanah. "PENGARUH RADIASI SINAR GAMMA TERHADAP KEMAMPUAN DEGRADASI LIGNIN PHANEROCHAETE CHRYSOSPORIUM DAN GANODERMA LUCIDUM." Jurnal Sains dan Teknologi Nuklir Indonesia 17, no. 1 (2016): 21. http://dx.doi.org/10.17146/jstni.2016.17.1.2400.

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Penelitian ini bertujuan untuk meningkatkan aktivitas enzim ektraseluler fungi lignoselulotik yakni Phanerochaete chrysosporium dan Ganoderma lucidum dalam mendegradasi limbah lignoselulosa. Lignoselulosa sulit didegradasi karena terdiri dari lignin, selulosa dan hemiselulosa. Phanerochaete chrysosporium dan Ganoderma lucidum dari kelompok White Rot Fungi dapat mendegradasi lignin karena mampu mensintesa enzim lignin peroksidase (LiP). Iradisi sinar gamma dosis rendah mampu menstimulasi peningkatan aktivitas enzim ekstraselular. Fungi Phanerochaete chrysosporium dan Ganoderma lucidum dalam med
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Glisic, M., M. Boskovic, M. Z. Baltic, et al. "Performance, intestinal histomorphology and bone composition of broiler chickens fed diets supplemented with genistein." South African Journal of Animal Science 50, no. 2 (2020): 241–52. http://dx.doi.org/10.4314/sajas.v50i2.7.

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The effect of dietary genistein on performance, intestinal morphology, caecal Lactobacillus spp. count, and tibia composition in broiler chickens after 21 and 37 days of feeding was investigated. A total of 360 Cobb 500 broiler chickens (21 days old) were randomly allocated to five treatments with six replicates of 12 birds each. They were fed a basal diet (C) or a basal diet supplemented with 200 (T1), 400 (T2), 600 (T3) and 800 (T4) mg genistein/kg of feed. Genistein supplementation did not affect feed intake, but improved bodyweight, weight gain and feed conversion ratio (FCR) after 21 days
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Obara, Sergio Y., Alexandre J. Bezutte, and Pedro L. C. A. Alves. "Desenvolvimento e composição mineral do picão-preto sob diferentes níveis de pH." Planta Daninha 12, no. 1 (1994): 52–56. http://dx.doi.org/10.1590/s0100-83581994000100008.

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Visando estudar a tolerância do picão-preto (Bidens pilosa) a diferentes níveis de pH do substrato, conduziu-se um ensaio em condições de câmara de crescimento e utilizando-se a técnica de hidroponia, no qual três plântulas foram transplantadas para recipientes contendo solução nutritiva de Hoagland & Arnon, com pH ajustado para 3,5, 4,0, 5,0, 6,0, 7,0 e 8,0. O delineamento experimental utilizado foi o inteiramente casualizado com três repetições. Ao final do período experimental, 42 dias após o transplante, observou-se que as plantas que se desenvolveram nos pHs 3,5 e 8,0 apresentaram-se
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Marsaro Júnior, Alberto Luiz, Moisés Mourão Júnior, Sônia Cristina Pereira Griffel, Wagner Ribeiro da Silva, and Andréia Esquivel Bressani de Melo. "EFICIÊNCIA DA TERRA DE DIATOMÁCEA NO CONTROLE DE Tribolium castaneum EM MILHO ARMAZENADO." Revista Acadêmica: Ciência Animal 7, no. 1 (2009): 79. http://dx.doi.org/10.7213/cienciaanimal.v7i1.8969.

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Tribolium castaneum é uma importante praga do milho armazenado no Brasil. O controle dessa praga é realizado principalmente com inseticidas químicos. O uso de protetores de grãos na região Norte do Brasil é raro. Nesse sentido, o objetivo desta pesquisa foi avaliar a eficiência da terra de diatomácea aplicada sobre milho armazenado em Roraima para o controle de T. castaneum. Grãos do híbrido BRS 2020 foram tratados com seis dosagens de terra de diatomácea, 0, 200, 400, 600, 800 e 1000 g.t-1. Cada tratamento, contendo 100 g de grãos, foi infestado com 30 adultos de T. castaneum e mantido em lab
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Hoit, Brian D., Nancy Ball, and Richard A. Walsh. "Invasive hemodynamics and force-frequency relationships in open- versus closed-chest mice." American Journal of Physiology-Heart and Circulatory Physiology 273, no. 5 (1997): H2528—H2533. http://dx.doi.org/10.1152/ajpheart.1997.273.5.h2528.

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We compared hemodynamics, ventricular function, and force-frequency relationships in six open-chest and six closed-chest anesthetized mice (FVB/N strain). Left ventricular (LV) pressure was measured with a 1.8- or 1.4-Fr Millar catheter placed via the right carotid artery and the LV apex in the closed- and open-chest state, respectively. Pacing was performed with electrodes placed either directly on atrial appendages (open chest) or with a 1-Fr bipolar catheter via the jugular vein (closed chest). Closed-chest animals had greater spontaneous heart rate (267 ± 106 vs. 147 ± 27 beats/min), LV sy
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32

Perry, L. A., R. Al Jassim, J. B. Gaughan, and N. W. Tomkins. "Effect of feeding forage characteristic of wet- or dry-season tropical C4 grass in northern Australia, on methane production, intake and rumen outflow rates in Bos indicus steers." Animal Production Science 57, no. 10 (2017): 2033. http://dx.doi.org/10.1071/an15314.

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Methane production (MP) from Bos indicus steers fed Chloris gayana hay characteristic of the ‘dry season’ (LQH), and a fresh Urochloa mosambicensis grass (PAS) or a C. gayana hay (HQH) characteristic of the ‘wet’ season was determined. A longitudinal feeding trial incorporated a 42-day covariate period (P1) in which Brahman steers (total n = 12) were fed ad libitum LQH (g/kg DM: crude protein (CP) 25; acid detergent fibre expressed exclusive of residual ash (ADFom) 487; DM digestibility (DMD) 380) followed by a 42-day treatment period where steers (n = 4 in each) were randomly assigned to PAS,
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Crumeyrolle, S., A. Schwarzenboeck, K. Sellegri, et al. "Overview of aerosol properties associated with air masses sampled by the ATR-42 during the EUCAARI campaign (2008)." Atmospheric Chemistry and Physics Discussions 12, no. 4 (2012): 9451–90. http://dx.doi.org/10.5194/acpd-12-9451-2012.

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Abstract. Within the frame of the European Aerosol Cloud Climate and Air Quality Interactions (EUCAARI) project the Météo-France aircraft ATR-42 performed 22 research flights, over central Europe and the North Sea during the intensive observation period in May 2008. For the campaign, the ATR-42 was equipped in order to study aerosol physical, chemical and optical properties, as well as cloud microphysics. During the campaign, continental air masses from Eastern and Western Europe were encountered, along with polar and Scandinavian air masses. For the 22 research flights, retroplume analyses al
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Walden, Ronald F., and Robert D. Wright. "Supraoptimal Root-zone Temperature Influences the Medium Solution and Growth of `Helleri' Holly." HortScience 30, no. 5 (1995): 1020–25. http://dx.doi.org/10.21273/hortsci.30.5.1020.

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Rooted cuttings of Ilex crenata Thunb. `Helleri' were grown for 12 weeks in pine bark with two root-zone temperature treatments (unheated or heated to 40C for 6 hours·day–1), two rates of limestone addition (0 or 6 kg·m–3), and three weekly N application rates (200, 400, or 600 mg·liter–1 as urea ammonium nitrate) in a factorial combination. Decreases in shoot and root dry weights due to root-zone heating (69% and 75%, respectively) or limestone addition (41% and 42%, respectively) were not influenced by N application rate. Effects of root-zone heating on medium solution characteristics, which
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35

Chungath, R. R., M. D. Witham, C. L. Clarke, et al. "42 Is Mitochondrial Function Measured by 31P Magnetic Resonance Spectroscopy Associated with Physical Performance in Older People with Functional Impairment?" Age and Ageing 50, Supplement_1 (2021): i12—i42. http://dx.doi.org/10.1093/ageing/afab030.03.

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Abstract Background Mitochondrial dysfunction has been proposed as a therapeutic target to improve muscle strength and endurance, but the contribution that mitochondrial dysfunction makes to impaired skeletal muscle performance in older people remains unclear. We studied the relationship between phosphocreatine recovery rate (a measure of skeletal muscle mitochondrial function) and physical performance in older people. Methods We analysed data from the Allopurinol in Functional Impairment (ALFIE) trial. Participants aged 65 and over, who were unable to walk 400 m in six minutes, underwent 31P
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Pónyai, Katinka, Márta Marschalkó, Mária Ackermanné Schöffler, et al. "Analysis of the patients with syphilis and gonorrhoea, on the basis of the National STD Centre, Department of Dermatology and Venerology, Semmelweis University (2005–2008)." Orvosi Hetilap 150, no. 38 (2009): 1765–72. http://dx.doi.org/10.1556/oh.2009.28679.

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Klinikánk STD Centrumában 2004 óta végezzük a syphilis, gonorrhoea és egyéb STD-fertőzésben szenvedők ellátását. STD Centrumunkon szűrőállomás működik, ahol anonim HIV- és syphilisszűrést végzünk. 2005. január 1-jétől 2008. december 31-ig összesen 42 114 orvos–beteg találkozás történt. 25 362 HIV- és syphilisszűrő vizsgálatot végeztünk el, orvosi vizittel egybekötve (HIV: 12 337, syphilis: 13 025). Önkéntes szűrővizsgálat 18 883 esetben történt (HIV: 16 614, syphilis: 2269). Négy év alatt 600 új syphilis- és 339 új gonorrhoeafertőzést diagnosztizáltunk. A kötelezően ajánlott HIV-szűrés során a
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37

Xavier, João, Sílvia Pinho, Jorge Silva, et al. "Postdural puncture headache in the obstetric population: a new approach?" Regional Anesthesia & Pain Medicine 45, no. 5 (2020): 373–76. http://dx.doi.org/10.1136/rapm-2019-101053.

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Background and objectivesThe gold standard for the treatment of postdural puncture headache (PDPH) is the epidural blood patch (EBP). Regional techniques—sphenopalatine ganglion block (SPGB), greater occipital nerve block (GONB) and trigger point infiltration (TPI)—can also be used for the treatment of PDPH. Our objective was to evaluate the efficacy of these peripheral nerve blocks (PNBs) in the treatment of PDPH.MethodsA retrospective study was conducted including all patients with PDPH in the obstetrics department of our institution between April 2016 and December 2017. Data were retrieved
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Martini, Tini. "Pengaruh Perilaku Kepemimpinan, Motivasi Berprestasi dan Budaya Sekolah Terhadap Kinerja Guru." JURNAL ILMU MANAJEMEN DAN BISNIS 10, no. 1 (2019): 17–27. http://dx.doi.org/10.17509/jimb.v10i1.15114.

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Abstract: The purpose of this study is to analyze the behavior of leadership, achievement motivation and school culture on performance. The specific objective of this study was to analyze (1) the leadership behavior of Principal at SMK Pasundan 3 Bandung; (2) determine the achievement motivation of teachers in teaching; (3) know the culture of the school; (4) determine the teachers performance; (5) determine the effect of principal leadership behavior on teacher performance; (6) the effect of achievement motivation on teacher performance; (7) determine the effect of school culture on teacher p
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Filatova, E., L. Alekseeva, E. Taskina, N. Kashevarova, A. Lila, and E. Sharapova. "AB0599 EFFICACY AND SAFETY OF COMBINATION THERAPY WITH NSAIDS AND ANTICONVULSANT, COMPARED WITH NSAID MONOTHERAPY FOR CHRONIC PAIN IN PATIENTS WITH OSTEOARTHRITIS OF THE KNEE JOINTS." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 1336.1–1336. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3062.

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Background:In 20-44% of patients with osteoarthritis of the knee joints neuroplastic changes occur due to central sensitization (1,2), which is the rationale for complex therapy, including centrally acting drugs, for more effective pain control.Objectives:To evaluate the efficacy and safety of combination therapy with NSAID and anticonvulsant in comparison with NSAID monotherapy in patients with osteoarthritis of the knee joints and signs of central sensitization or nocyplastic painMethods:The study included 60 women with osteoarthritis of the knee joints (OAK) with signs of nocyplastic pain.
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Raj, Kiran Karthik, R. N. Pandey, Bhupinder Singh, M. C. Meena, A. Talukdar, and D. Chakraborty. "Response of soybean genotypes to iron limiting stress in calcareous vertisol under ambient and elevated CO2 and temperature conditions." Journal of Environmental Biology 42, no. 2 (2021): 295–301. http://dx.doi.org/10.22438/jeb/42/2/mrn-1226.

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Aim: To compare the relative performance of two contrasting genotypes of soybean to iron limiting conditions under ambient and elevated CO2 and temperature conditions. Methodology: A pot culture experiment was performed using calcareous vertisol soil. The environmental factors viz. CO2 and temperature were combined and applied as a single factor with two levels: a-[CO2+T] (400±10 µmol mol-1, day/night temperature 30oC/22oC) and e-[CO2+T] (610±10 µmol mol-1, day/night temperature 34oC/26oC). Soybean genotype that differed in iron use efficiency was used as another factor and two contrasting gen
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Guilhot, François, Claude Preudhomme, Joelle Guilhot, et al. "Significant Higher Rates of Undetectable Molecular Residual Disease and Molecular Responses with Pegylated Form of Interferon a2a in Combination with Imatinib (IM) for the Treatment of Newly Diagnosed Chronic Phase (CP) Chronic Myeloid Leukaemia (CML) Patients (pts): Confirmatory Results at 18 Months of Part 1 of the Spirit Phase III Randomized Trial of the French CML Group (FI LMC)." Blood 114, no. 22 (2009): 340. http://dx.doi.org/10.1182/blood.v114.22.340.340.

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Abstract Abstract 340 Background: IM 400 mg daily is the front-line treatment of CP CML, but provides only 50% major molecular responses (MMR) at 18 months (Mo). Aims: we designed a phase III randomized multicenter open-label prospective trial comparing IM 400 mg/d (n=159) with 3 experimental arms: IM 600 mg/d (n=160), IM 400 mg/d combined to s/c cytarabine (Ara-C), (20 mg/m2/d, d15-28 of 28-day cycles)(n=158) and IM 400 mg/d combined to s/c Peg-IFN2a (90 μg/wk) (n=159). Methods: Pts were allocated at a 1.1.1.1 ratio, stratified by Sokal risk groups. Molecular assessments were centralized, bli
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Stevenson, D. S., P. J. Young, V. Naik, et al. "Tropospheric ozone changes, radiative forcing and attribution to emissions in the Atmospheric Chemistry and Climate Model Intercomparison Project (ACCMIP)." Atmospheric Chemistry and Physics 13, no. 6 (2013): 3063–85. http://dx.doi.org/10.5194/acp-13-3063-2013.

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Abstract. Ozone (O3) from 17 atmospheric chemistry models taking part in the Atmospheric Chemistry and Climate Model Intercomparison Project (ACCMIP) has been used to calculate tropospheric ozone radiative forcings (RFs). All models applied a common set of anthropogenic emissions, which are better constrained for the present-day than the past. Future anthropogenic emissions follow the four Representative Concentration Pathway (RCP) scenarios, which define a relatively narrow range of possible air pollution emissions. We calculate a value for the pre-industrial (1750) to present-day (2010) trop
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al-Janabi, S. M., R. J. Honeycutt, M. McClelland, and B. W. Sobral. "A genetic linkage map of Saccharum spontaneum L. 'SES 208'." Genetics 134, no. 4 (1993): 1249–60. http://dx.doi.org/10.1093/genetics/134.4.1249.

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Abstract The arbitrarily primed polymerase chain reaction was used to detect single-dose polymorphisms that, in turn, were used to generate a linkage map of a polyploid relative of cultivated sugarcane, Saccharum spontaneum 'SES 208' (2n = 64). The mapping population was composed of 88 progeny from a cross between SES 208 and a diploidized haploid derived from SES 208 by anther culture, ADP 85-0068. This cross allowed direct analysis of meiosis in SES 208 and gametic segregation ratios to be observed. One hundred twenty-seven 10-mer oligonucleotide primers of arbitrary sequence were selected f
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Barbosa, Fellipe Freitas, Aloízio Soares Ferreira, Gustavo Gattás, et al. "Níveis de plasma sangüíneo em pó em dietas para leitões desmamados aos 21 dias de idade." Revista Brasileira de Zootecnia 36, no. 4 suppl (2007): 1052–60. http://dx.doi.org/10.1590/s1516-35982007000500010.

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Objetivando-se avaliar níveis de inclusão de plasma sangüíneo em pó nas dietas para leitões desmamados aos 21 dias de idade, foram utilizados 112 animais com peso inicial de 5,90 ± 0,40 kg distribuídos em delineamento experimental de blocos ao acaso com quatro tratamentos e sete repetições com quatro animais por unidade experimental, em três períodos subseqüentes: 21 aos 28 dias (período 1), 29 aos 35 dias (período 2) e 36 aos 42 dias (período 3). Os leitões foram mantidos no experimento dos 43 aos 56 dias (período 4) recebendo dieta convencional de creche. Os tratamentos consistiram de níveis
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Coelho, Shana M. O., Elina Reinoso, Ingrid A. Pereira, et al. "Virulence factors and antimicrobial resistance of Staphylococcus aureus isolated from bovine mastitis in Rio de Janeiro." Pesquisa Veterinária Brasileira 29, no. 5 (2009): 369–74. http://dx.doi.org/10.1590/s0100-736x2009000500002.

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The study was conducted to characterize pheno-genotypically the virulence factors and resistance pattern of Staphylococcus aureus isolates from milk samples of cows with subclinical mastitis. All hemolytic isolates presented beta-hemolysin, and 38% of the non-hemolytic isolates were able to express hemolysins in the presence of a beta-hemolytic strain. The amplification of the coa-gene displayed four different size polymorphisms with about 400 bp, 600 bp, 700 bp and 900 bp. The spaA gene that encodes the IgG-binding region of protein A revealed sizes of 700 bp and 900 bp. The amplification of
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Santos, Eunice Pereira Gonçalves dos, Débora Rosana Marques Lehmann, Marisa Santos, and Áurea Maria Randi. "Spore germination of Gleichenella pectinata (Willd.) Ching (Polypodiopsida-Gleicheniaceae) at different temperatures, levels of light and pH." Brazilian Archives of Biology and Technology 53, no. 6 (2010): 1309–18. http://dx.doi.org/10.1590/s1516-89132010000600007.

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This study investigated the effects of different temperatures (25 and 30 ± 2 ºC), light levels (62, 42, 22 and 5% of natural light), and pH (4.0, 4.5, 5.0, 5.5, 6.0 and 6.7) on the spore germination of Gleichenella pectinata. To accomplish this, the spores were surface sterilized and sown in bottles containing mineral medium. The spores of G. pectinata are monolets and the perispore surface can show large and irregular deposits. During germination, filamentous gametophytes with and without developing rhizoids were observed. Only gametophytes which presented developed rhizoids were able to reac
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McManus, J., D. Blake, and S. Ratnaike. "An assay of uroporphyrinogen decarboxylase in erythrocytes." Clinical Chemistry 34, no. 11 (1988): 2355–57. http://dx.doi.org/10.1093/clinchem/34.11.2355.

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Abstract Measurement of uroporphyrinogen decarboxylase (UROD; EC 4.1.1.37) activity in erythrocytes is useful in distinguishing between familial porphyria cutanea tarda (PCT), in which UROD activities are low, and acquired PCT, in which UROD activity is normal. In this method for measuring UROD, pentacarboxylic acid porphyrinogen I (PPI) is used as substrate. A sample of the patient's whole blood is incubated with PPI at 37 degrees C for 30 min at pH 6.0. The reaction is stopped by adding trichloroacetic acid/dimethyl sulfoxide containing mesoporphyrin (internal standard). The coproporphyrin s
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Djekic, Vera, Sreten Mitrovic, Sasa Obradovic, Marija Vukasinovic, and Dragan Sefer. "Effect of different varieties of triticale on product characteristics in broiler chickens." Veterinarski glasnik 66, no. 5-6 (2012): 345–53. http://dx.doi.org/10.2298/vetgl1206345d.

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The aim of this paper was to determine how forage triticale in diets for fattening broilers influence the body weight and weight gain of broiler chickens for fattening. The survey was conducted on 400 chickens for fattening provenance Ross 308 for a period of 42 days. On this occasion, four groups of chickens were formed, with 100 chickens being treated in each group, as follows: K (classic mixture for fattening broilers) and O-I (mixtures with triticale variety Kg 20), O-II (mixtures with triticale Favorit) and O-III group (mixtures with triticale Trijumf). The highest average body mass in th
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Xepapadaki, Paraskevi, Paraskevi Korovessi, Claus Bachert, et al. "Evolution of Airway Inflammation in Preschoolers with Asthma—Results of a Two-Year Longitudinal Study." Journal of Clinical Medicine 9, no. 1 (2020): 187. http://dx.doi.org/10.3390/jcm9010187.

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Fractional exhaled nitric oxide (FeNO) is a non-invasive marker for eosinophilic airway inflammation and has been used for monitoring asthma. Here, we assess the characteristics of FeNO from preschool to school age, in parallel with asthma activity. A total of 167 asthmatic children and 66 healthy, age-matched controls were included in the 2-year prospective PreDicta study evaluating wheeze/asthma persistence in preschool-aged children. Information on asthma/rhinitis activity, infections and atopy was recorded at baseline. Follow-up visits were performed at 6-month intervals, as well as upon e
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Iacovelli, Roberto, Valentina Orlando, Antonella Palazzo, and Enrico Cortesi. "Clinical and pathological features of primary renal angiosarcoma." Canadian Urological Association Journal 8, no. 3-4 (2014): 223. http://dx.doi.org/10.5489/cuaj.1585.

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Introduction: We review all cases of renal angiosarcoma described in the medical literature to describe its clinical and histological features.Methods: The search term was “angiosarcoma of the kidney.” All articles or case reports in English, French, German or Spanish published until March 15, 2013 were considered. When available, data that focused on clinical and pathological features were extracted.Results: In total, the final cohort included 42 cases. The median overall survival (OS) was 5.0 months (95% confidence interval [CI], 2.1-7.9). Patients with metastatic disease had more than a thr
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