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Journal articles on the topic '6H-chromeno [4'

Author: Grafiati

Published: 4 June 2025

Last updated: 1 August 2025

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1

Morteza, Shiri, Fathollahi-Lahroud Mina, and Yasaei Zahra. "A novel strategy for the synthesis of 6H-chromeno [4, 3-b] quinoline by intramolecular Heck cyclization." Tetrahedron 73, no. 17 (2017): 2501–3. https://doi.org/10.1016/j.tet.2017.03.043.

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A novel procedure for the synthesis of various derivatives of 6H-chromeno [4, 3-b] quinolines from intramolecular Heck reaction of 2-chloro-3-(phenoxymethyl) quinolines is described in this study. Intramolecular cyclization of N-alkylated indoles was efficiently investigated as well. The reaction is catalyzed by bis (triphenylphosphine) palladium (II) dichloride in acetonitrile at 80 °C.

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2

Zemanová, Ivana, Michaela Potančoková, and Renata Gašparová. "Synthesis of 4-OXO-4H-Chromene Derivative with Fused Benzodiazepine Ring." Nova Biotechnologica et Chimica 15, no. 1 (2016): 85–89. http://dx.doi.org/10.1515/nbec-2016-0009.

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Abstract 6-Acetylbenzo[b]chromeno[2,3-e][1,4]diazepin-13(6H)-one 6 was synthesized by reaction of 4- oxo-4H-chromene-3-carboxaldehyde 1 with 1,2-diaminobenzene 2 followed by cyclisation of formed Schiff base 3 and spontaneous oxidation of dihydrodiazepine 4 by air oxygen. Finally, diazepine 5 was acetylated at N(6) by reaction with acetic anhydride.

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3

Firoozpour, Loghman, Hoda Yahyavi, Ramona Ejtemaei, Setareh Moghimi, and Alireza Foroumadi. "A One-Pot, Three-Component, Solvent-Free Synthesis of Novel 6H-Chromeno[3’,4’:5,6]Pyrido[2,3-d]Pyrimidine-Triones under Microwave Irradiation." Journal of Chemical Research 42, no. 12 (2018): 604–7. http://dx.doi.org/10.3184/174751918x15414289771620.

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A green and efficient method for preparing novel heterocyclic systems is established through the reaction of differently substituted benzaldehydes, barbituric acid and 4-amino-2H-chromene-2-one under solvent-free conditions. This method affords 6H-chromeno[3’,4’:5,6] pyrido[2,3-d]pyrimidine-trione derivatives in high yields and short reaction times.

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4

Shokol, Tetyana, Natalia Gorbulenko, and Volodymyr Khilya. "Synthesis of chromones, annulated with oxygen-containing heterocycles with two hetero atoms at C(7)-C(8) bond." French-Ukrainian Journal of Chemistry 7, no. 1 (2019): 121–39. http://dx.doi.org/10.17721/fujcv7i1p121-139.

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The present review represented the advanced synthetic strategies for chromones annulated at the C(7)-C(8) bond with five-membered, six-membered, and seven-membered oxygen-containing heterocycles with two heteroatoms, such as 6H-[1,3]dioxolo[4,5-h]chromen-6-one, 2,3-dihydro-7H-[1,4]dioxino[2,3-h]chromen-7-one, 3,4-dihydro-2H,8H-[1,4]dioxepino[2,3-h]chromen-8-one, 2,3-dihydro-1H,7H-chromeno[7,8-b][1,4]oxazin-7-one, 4H,12H-pyrano[2,3-a]phenoxazine-4-one and 9,10-dihydro-4H,8H-chromeno[8,7-e][1,3]oxazin-4-one. The biological activity of naturally occurring and modified synthetic fused hetarenochro

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5

Mokhonova, Inna D., Evgenij A. Maksimov, Irina V. Ledenyona, Alevtina Y. Yegorova, and Khidmet S. Shikhaliev. "Reactions of 3H-furan-2-ones and 2H-chromen-2-ones with pyrazole-3(5)-diazonium salts." Heterocyclic Communications 24, no. 4 (2018): 183–85. http://dx.doi.org/10.1515/hc-2017-0192.

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AbstractDerivatives of the new heterocyclic system, 6H-chromeno[4,3-e]pyrazolo[5,1-c][1,2,4]triazin-6-one, were obtained by the reaction of pyrazole-3(5)-diazonium salts with 4-hydroxy-2H-chromen-2-one. Similar reactions with 5-phenyl-3H-furan-2-one followed by intramolecular heterocyclization furnished 6-(4-halophenyl)-7-alkyl-2-phenylfuro[2,3-e]pyrazolo[5,1-c][1,2,4]triazines.

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6

Ren, Demin, Xiaolian Hu, Yulin Huang, Xinliang Fu, and Xiaofang Li. "Synthesis of 6-Aryl-6H-Chromeno[4’,3’:4,5][1,3]Thiazolo[3,2-A]Benzimidazoles from 2-Aryl-3-Nitro-2H-Chromenes and 1H-Benzimidazole-2-Thiol." Journal of Chemical Research 42, no. 7 (2018): 374–76. http://dx.doi.org/10.3184/174751918x15314848760271.

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A number of 6-aryl-6H-chromeno[4’,3’:4,5][1,3]thiazolo[3,2-a]benzimidazole derivatives were synthesised by the reaction of 2-aryl-3-nitro-2H-chromenes with 1H-benzimidazole-2-thiol in the presence of Cu(OAc)2•H2O in moderate yields via successive C-N and C-S bond formations. The structures of all the products were characterised thoroughly by NMR and HRMS spectroscopy together with X-ray crystallographic analysis.

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7

Kumari, Sudesh, M. Rajeswari, and Jitender M. Khurana. "A Green Approach for the Synthesis of Novel 7,11-Dihydro-6H-chromeno[3,4-e]isoxazolo[5,4-b]pyridin-6-one Derivatives Using Acidic Ionic Liquid [C4mim][HSO4]." Australian Journal of Chemistry 69, no. 9 (2016): 1049. http://dx.doi.org/10.1071/ch16014.

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A multicomponent reaction capable of affording a wide range of novel 7,11-dihydro-6H-chromeno[3,4-e]isoxazolo[5,4-b]pyridin-6-one derivatives via one-pot three-component condensation of 4-hydroxycoumarin, aromatic aldehydes, and 5-amino-3-methylisoxazole in ionic liquid 1-butyl-3-methylimidazolium hydrogen sulfate ([C4mim][HSO4]) is reported. Structures have been confirmed by spectral and X-ray studies. Crystal packing of 4b has also been reported. Green solvent, short reaction time, easy workup, and high yields are the salient features of the present protocol.

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8

Litvinov, Yu M., and A. M. Shestopalov. "Convenient selective synthesis of 5,7,8,9-tetrahydro-4H,6H-chromeno[2,3-d][1,3]oxazin-4-ones." Russian Chemical Bulletin 58, no. 2 (2009): 479–81. http://dx.doi.org/10.1007/s11172-010-0037-z.

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9

Choudhary, M. Iqbal, Alain Meli Lannang, Shazia Anjum, Hoong-Kun Fun, David Lontsi, and Jean Gustave Tangmouo. "1,13-Dimethyl-6H,7H,8H-chromeno[3′,4′:5,6]pyrano[3,2-c]chromene-6,8-dione." Acta Crystallographica Section E Structure Reports Online 62, no. 1 (2005): o116—o118. http://dx.doi.org/10.1107/s1600536805040523.

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10

Swaminathan, K., K. Sethusankar, G. Siva Kumar, and M. Bakthadoss. "Crystal structures and conformational analyses of three pyranochromene derivatives." Acta Crystallographica Section E Crystallographic Communications 71, no. 8 (2015): 926–30. http://dx.doi.org/10.1107/s2056989015012967.

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The title compounds, C27H20O6, (I) [systematic name: methyl 7-oxo-14-phenyl-1H,7H,14H-pyrano[3,2-c:5,4-c′]dichromene-14a(6bH)-carboxylate], C24H22O5, (II) [systematic name: methyl 1-oxo-6-phenyl-2,3,4,12b-tetrahydro-1H,6H-chromeno[3,4-c]chromene-6a(7H)-carboxylate], and C25H23N3O4, (III) [systematic name: 6-(4-ethylphenyl)-2,4-dimethyl-1,3-dioxo-2,3,4,12b-tetrahydro-1H,6H-chromeno[4′,3′:4,5]pyrano[2,3-d]pyrimidine-6a(7H)-carbonitrile], are pyranochromene derivatives. The central pyran rings (B) of compounds (I) and (III) adopt half-chair conformations, whereas that of compound (II) adopts a so

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11

Shiri, Morteza, Mina Fathollahi-Lahroud, and Zahra Yasaei. "A novel strategy for the synthesis of 6H-chromeno [4, 3-b] quinoline by intramolecular Heck cyclization." Tetrahedron 73, no. 17 (2017): 2501–3. http://dx.doi.org/10.1016/j.tet.2017.03.043.

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12

Litvinov, Yu M., and A. M. Shestopalov. "ChemInform Abstract: Convenient Selective Synthesis of 5,7,8,9-Tetrahydro-4H,6H-chromeno[2,3-d][1,3]oxazin-4-ones." ChemInform 41, no. 36 (2010): no. http://dx.doi.org/10.1002/chin.201036170.

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13

Bao, Jin-ping, Cui-lian Xu, Guo-yu Yang, Cai-xia Wang, Xin Zheng, and Xin-xin Yuan. "Novel 6a,12b-Dihydro-6H,7H-chromeno[3,4-c] chromen-6-ones: Synthesis, Structure and Antifungal Activity." Molecules 24, no. 9 (2019): 1745. http://dx.doi.org/10.3390/molecules24091745.

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A new series of coumarin derivatives, 7-hydroxy-7-(trifluoromethyl)-6a,12b-dihydro-6H,7H-chromeno[3,4-c]chromen-6-ones 3a–p, were synthesized via Michael addition, transesterification and nucleophilic addition from the reaction of 3-trifluoroacetyl coumarins and phenols in the presence of an organic base. The products were characterized by infrared spectroscopy (IR), hydrogen nuclear magnetic resonance spectroscopy (1H-NMR), carbon nuclear magnetic resonance spectroscopy (13C-NMR) and high-resolution mass spectrometer (HRMS). Single crystal X-ray analysis of compounds 3a and 3n clearly confirm

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14

Irgashev, Roman A., Alexander S. Steparuk, and Gennady L. Rusinov. "Synthesis of 6H,7H-chromeno[3′,4′:4,5]thieno[3,2-b]indol-6-ones using the Fischer indolization reaction." Tetrahedron Letters 79 (August 2021): 153297. http://dx.doi.org/10.1016/j.tetlet.2021.153297.

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15

Sultana, Rizuana. "Synthesis of Chromene 4 Aldehyde and 6-Phenyl-6h-Chromeno [4,3-B] Quinoline Derivatives as Anticancer and Apoptosis Inducing Agents." International Journal for Research in Applied Science and Engineering Technology 9, no. 10 (2021): 1764–72. http://dx.doi.org/10.22214/ijraset.2021.38647.

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Abstract: A series of novel chromene 3-aldehyde and quinoline derivatives have been synthesized using diversely substituted nitroarenes in the presence of In, dil. HCl, H2O (reductive amination) and evaluated for in vitro cytotoxic activity in three different cancer cell lines (MDA-MB-453, MCF-7, A549 and PC3). The synthetic strategy utilized to access these hybrids is operationally simple and works with great substrate scope. Interestingly, compound 6i was induced apoptosis to a significant extent in MDA-MB-453 cell lines. And these selected compounds 6i was led to morphological changes after

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16

Pangajavalli, S., R. Ranjithkumar, N. Srinivasan, S. Ramaswamy, and S. Selvanayagam. "Crystal structures of 6a,6b,7,11a-tetrahydro-6H,9H-spiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,3′-indoline]-2′,6-dione and 5′-methyl-6a,6b,7,11a-tetrahydro-6H,9H-spiro[chromeno[3′,4′:3,4]pyrrolo[1,2-c]thiazole-11,3′-indoline]-2′,6-dione." Acta Crystallographica Section E Crystallographic Communications 75, no. 2 (2019): 246–50. http://dx.doi.org/10.1107/s2056989019000045.

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The title compounds, C20H16N2O3S, (I), and C21H18N2O3S, (II), differ by the presence of a methyl group in position 5 on the 1H-indole-2-one ring of compound (II). The two compounds have a structural overlap r.m.s. deviation of 0.48 Å. There is a significant difference in the conformation of the thiazolidine ring: it has a twisted conformation on the fused N—C bond in (I), but an envelope conformation in compound (II) with the S atom as the flap. The planar pyrrolidine ring of the indole ring system is normal to the mean plane of the five-membered pyrrolidine ring of the pyrrolothiazole unit in

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17

Kostritskiy, Alexander Yu, Marina G. Nakonechnikova, Olga V. Fedotova, and Nina V. Pchelintseva. "Synthesis and Heterocyclization of 4-Hydroxy-3 - ((2-hydroxy-4,4-dimethyl-6-oxocyclohex1-en-1-yl) (aryl) methyl) -2H-chromen-2-ones." Izvestiya of Saratov University. New Series. Series: Chemistry. Biology. Ecology 20, no. 4 (2020): 362–71. http://dx.doi.org/10.18500/1816-9775-2020-20-4-362-371.

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The possibility of obtaining asymmetric 1,5-diketones based on 4-hydroxy-2H-chromen-2-one and dimedone by three-component condensation in the presence of L-proline as a catalyst is shown. As a result, a series of 4-hydroxy3 - ((2-hydroxy-4,4-dimethyl-6-oxocyclohex1-en-1-yl) (aryl) methyl) -2H-chromen-2-ones was obtained with a yield of 25 up to 73%. The study revealed that the highest yield was observed for compounds containing fragments of ortho-substituted aldehydes capable of forming a hydrogen bond. For meta- and para-substituted – the lowest yield was observed. In the case of ortho-substi

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18

Kumar, Alleni Suman, Rathod Aravind Kumar, Vavilapally Satyanarayana, et al. "Catalyst-Free Synthesis of Novel 6-Phenyl-6H-chromeno [4, 3-b] quinoline Derivatives at RT: Their Further Structure Evaluation Leads to Potential Anti-cancer Agents." Natural Product Communications 12, no. 7 (2017): 1934578X1701200. http://dx.doi.org/10.1177/1934578x1701200732.

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A variety of novel quinoline derivatives (6-phenyl-6 H-chromeno [4,3- b] quinoline) have been prepared by using 4-chloro-2-phenyl-2 H-chromene-3-carbaldehyde and various substituted of aromatic anilines as starting materials. This is the first example on the preparation of quinolines through this novel method. And the resulting quinoline derivatives further structure evolution is leads to an anti cancer agents. Our preliminary data of model compound (7i) on three cancer cell lines (B16F10, MCF7 and A549) suggested decent anticancer activity on two cell lines (B16F10 and MCF7) with IC50 values

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19

Iaroshenko, Viktor O., Sajid Ali, Tariq Mahmood Babar, et al. "4-Chloro-3-(trifluoroacetyl)coumarin as a novel building block for the synthesis of 7-(trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones." Tetrahedron Letters 52, no. 3 (2011): 373–76. http://dx.doi.org/10.1016/j.tetlet.2010.11.028.

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20

Syed Abuthahir, S., M. NizamMohideen, V. Viswanathan, D. Velmurugan, and J. Nagasivarao. "Crystal structure of 6-(4-chlorophenyl)-6a-nitro-6a,6b,8,9,10,12a-hexahydro-6H,7H-spiro[chromeno[3,4-a]indolizine-12,11′-indeno[1,2-b]quinoxaline]." Acta Crystallographica Section E Crystallographic Communications 75, no. 2 (2019): 255–59. http://dx.doi.org/10.1107/s2056989019000975.

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The title compound, C35H27ClN4O3, crystallized with two independent molecules (A and B) in the asymmetric unit. In both molecules, the pyran and pyridine rings adopt envelope and chair conformations, respectively. The conformation of the pyrrolidine and cyclopentene rings differ in the two molecules; twisted and flat, respectively, in molecule A, but envelope and twisted, respectively, in molecule B. In both molecules, there is a C—H...N intramolecular hydrogen bond present. In both molecules, the oxygen atoms of the nitro groups are disordered as is the chlorine atom in molecule B. In the cry

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21

Sultana, Rizuana, and Ravinder Reddy Tippanna. "A Novel and Different Approach for the Synthesis of Quinoline Derivatives Starting Directly from Nitroarenes and Their Evaluation as Anti-Cancer Agents." International Journal of Chemistry 12, no. 1 (2020): 99. http://dx.doi.org/10.5539/ijc.v12n1p99.

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A series of new quinoline derivatives (6-phenyl-6H-chromeno, [4,3-b] quinoline) have been prepared by using 4-chloro-2-phenyl-2H-chromene-3-carbaldehyde and various substituted nitroarenes as starting materials in the presence of Tin (II) chloride dihydrate and ethanol. The conversion in this synthesis involves the following steps (i) reduction of nitroarenes to anilines, (ii) Coupling of the anilines, chromene aldehydes (iii) Cyclization of resulting species and (iv) dehydration of cyclic intermediates. Several new quinolones have been prepared. We screened eight compounds of this novel serie

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22

Iaroshenko, Viktor O., Sajid Ali, Tariq Mahmood Babar, et al. "ChemInform Abstract: 4-Chloro-3-(trifluoroacetyl)coumarin as a Novel Building Block for the Synthesis of 7-(Trifluoromethyl)-6H-chromeno[4,3-b]quinolin-6-ones." ChemInform 42, no. 16 (2011): no. http://dx.doi.org/10.1002/chin.201116153.

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23

Suman, Kancharla, Jyothi Prashanth, Koya Prabhakara Rao, Madala Subramanyam, Vejendla Anuradha, and Mandava Venkata Basaveswara Rao. "Facile Synthesis of 6-Phenyl-6h-chromeno [4, 3-b] Quinoline Derivatives using NaHSO4@SiO2 Re-usable Catalyst and Their Antibacterial Activity Study Correlated by Molecular Docking Studies." Letters in Drug Design & Discovery 17, no. 7 (2020): 929–38. http://dx.doi.org/10.2174/1570180816666190731115809.

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Background: Heterocyclic compounds containing heteroatoms (O, N and S) as part of five or six-membered cyclic moieties exhibited various potential applications, such as pharmaceutical drugs, agrochemical products and organic materials. Among many known heterocyclic moieties, quinoline and its derivatives are one of the privileged scaffolds found in many natural products. In general, quinoline derivatives could be prepared by utilizing ortho-substituted anilines and carbonyl compounds containing a reactive α-methylene group of well-known reaction routes like Friedlander synthesis, Niemantowski

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24

Mahdavinia, Gholam Hossein, та Somayyeh Peikarporsan. "Cyclization of α,α′-bis(substituted-benzylidene)cyclohexanones and 4-hydroxycoumarin: synthesis of 11-benzylidene-8,9,10,11-tetrahydro-7-phenyl-6H,7H-chromeno[4,3-b]chromen-6-ones as new pyranochromene derivatives". Monatshefte für Chemie - Chemical Monthly 144, № 3 (2012): 415–19. http://dx.doi.org/10.1007/s00706-012-0845-y.

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25

Anuradha, T., J. Naga Siva Rao, P. R. Seshadri, and R. Raghunathan. "6a-Nitro-6-(2,2,7,7-tetramethyltetrahydro-3aH-bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran-5-yl)-6a,6b,7,8,9,11a-hexahydro-6H-spiro[chromeno[3,4-a]pyrrolizine-11,11′-indeno[1,2-b]quinoxaline]." Acta Crystallographica Section E Structure Reports Online 70, no. 1 (2013): o38—o39. http://dx.doi.org/10.1107/s1600536813032467.

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26

Mahdavinia, Gholam Hossein, та Somayyeh Peikarporsan. "ChemInform Abstract: Cyclization of α,α′-Bis(substituted-benzylidene)cyclohexanones and 4-Hydroxycoumarin: Synthesis of 11-Benzylidene-8,9,10,11-tetrahydro-7-phenyl-6H,7H-chromeno [4,3-b]chromen-6-ones as New Pyranochromene Derivatives." ChemInform 44, № 30 (2013): no. http://dx.doi.org/10.1002/chin.201330157.

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27

Tavakoli-Hoseini, Niloofar, Majid M. Heravi, Fatemeh F. Bamoharram, Abolghasem Davoodnia, and Mitra Ghassemzadeh. "An unexpected tetracyclic product isolated during the synthesis of biscoumarins catalyzed by [MIM(CH2)4SO3H][HSO4]: Characterization and X-ray crystal structure of 7-(2-hydroxy-4-oxo-4H-chromen-3-yl)-6H,7H-chromeno[4,3-b]chromen-6-one." Journal of Molecular Liquids 163, no. 3 (2011): 122–27. http://dx.doi.org/10.1016/j.molliq.2011.08.007.

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28

Namboothiri, Irishi N., Banamali Laha, and Alati Suresh. "Regio- and stereoselective synthesis of functionalized tetrahydrobenzochromenes and hexahydrochromenochromenones via [4+2] annulation of curcumins with nitrochromenes." Organic & Biomolecular Chemistry, 2023. http://dx.doi.org/10.1039/d2ob02211g.

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A base-mediated regio- and stereoselective synthesis of functionalized tetrahydro-6H-benzo[c]chromenes and hexahydro-1H,6H-chromeno[6,5-c]chromenone is disclosed here. It involves a [4+2] annulation via cascade double and triple Michael reactions between curcumins and nitrochromenes...

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29

Kishore, Dakoju Ravi, Kurella Mounika, Gedu Satyanarayana, Komal Goel, and Jakkula Naveen. "Microwave-Assisted Domino Povarov-Type [4+2] Cycloaddition: A Rapid Access to 7-Phenyl-6H-chromeno[4,3-b]quinolines." Synthesis, December 15, 2022. http://dx.doi.org/10.1055/s-0041-1738429.

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AbstractA convenient, facile, and eco-friendly approach to synthesizing 7-phenyl-6H-chromeno[4,3-b]quinolines under microwave irradiation is presented. The current strategy enabled the synthesis of chromenoquinoline frameworks at 80 °C under shorter reaction times via intermolecular Schiff base formation followed by an intramolecular inverse demand hetero-Diels–Alder [4+2]-cycloaddition reaction by using a catalytic amount of copper triflate as the sole catalyst. Consequently, one C–N and two C–C bonds are constructed in a single pot, and a wide spread of 7-phenyl-6H-chromeno[4,3-b]quinolines

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30

Panjacharam, Paranimuthu, and Sabbasani Rajasekhara Reddy. "Sustainable Strategy to Access Fused Chromenoquinoline Analogues via Doebner–Von Miller‐Type Reaction and Mechanistic Insights." Asian Journal of Organic Chemistry, July 9, 2025. https://doi.org/10.1002/ajoc.70106.

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AbstractIn this study, we report a metal‐ and oxidant‐free synthesis of fused chromenoquinolines via an acetic acid‐promoted Doebner–Von Miller‐type reaction. This effective method allows substituted anilines to react with 4‐chloro‐2H‐chromene‐3‐carbaldehydes in an eco‐friendly way, facilitating the formation of new C─N and C─C bonds while building fused polycyclic heteroaromatic rings. This protocol is broadly applicable for the synthesis of diverse 6H‐chromeno[4,3‐b]quinolines, which serve as versatile scaffolds for the subsequent cross‐coupling reactions and C(sp3)─H oxidation.

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31

Sultana, Rizuana, and Ravinder Reddy Tippanna. "Chromene, Quinoline Hybrids as Potential Anti-Cancer Agents: A Novel and Distinct Approach for the Synthesis of Quinoline Derivatives.." Letters in Organic Chemistry 17 (January 22, 2020). http://dx.doi.org/10.2174/1570178617666200122095829.

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: A series of novel quinoline derivatives (6-phenyl-6H-chromeno[4,3-b]quinoline) have been prepared by using 4-chloro-2-phenyl-2H-chromene-3-carbaldehyde and various substituted isocyanides as starting materials in the presence of HClO4-SiO2 and Methanol. We screened eighteen compounds of this novel series (6a-r) in six different cancer cell lines (A549 (lung cancer cells), DU145 (prostate cancer cells), PC3 (prostate cancer cells), MCF7 (lung cancer cells), HT 29, HCT 116 (colon cancer cells)). Most of the compounds showed anti-cancer activity and compound 6b showed good cytotoxicity IC50 = 2

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32

Bargavi, S., S. Mayakrishnan, N. Uma Maheswari, and S. Lakshmi. "Synthesis, crystallographic, quantum chemical and molecular docking studies of 4-benzoyl-1,2,3,11a-tetrahydro-6H-chromeno[3,2-e]imidazo[1,2-a]pyridin-6-one." Results in Chemistry, December 2022, 100751. http://dx.doi.org/10.1016/j.rechem.2022.100751.

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33

Gomathi, S., Era Dravida Thendral, G. Sivakumar, V. Sabari, and G. Usha. "Methyl (6R*,6aR*,12bR*)-2,4-dimethyl-6-(2-methylphenyl)-1,3-dioxo-2,3,4,6a,7,12b-hexahydro-1H,6H-chromeno[4′,3′:4,5]pyrano[2,3-d]pyrimidine-6a-carboxylate." IUCrData 2, no. 6 (2017). http://dx.doi.org/10.1107/s2414314617008124.

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In the title compound, C24H24N2O6, the mean planes of the pyran rings (AandB) are inclined to one another by 69.2 (1)°, while the aromatic ring (D) of the chromene ring system makes dihedral angles of 63.42 (11) and 66.81 (12)° with the pyrimidine (C) and benzene (E) rings, respectively. Pyran ringAhas an half-chair conformation, while pyran ringBhas an envelope conformation, with the spiro C atom as the flap. In the crystal, molecules are linked by C—H...O hydrogen bonds, forming a supramolecular three-dimensional network. There are also a number of C—H...π interactions present.

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Vanukuri, Omkar Reddy, Mohan Gundluru, Poojitha Bellala, Rama Sekhara Reddy Dachuru, and Suresh Reddy Cirandur. "Facile one-pot green synthesis, antioxidant and antimicrobial activities of 7-(substituted phenyl)-7,11-dihydro-6H,8H-chromeno[3′,4′:5,6]pyrano[2,3-d]pyrimidine-6,8,10(9H)-trione derivatives." Synthetic Communications, January 25, 2025, 1–13. https://doi.org/10.1080/00397911.2025.2455521.

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Parthiban, Devendiran, Muniyan Ramasamy Kuppusamy, Chinnaswamy Vanitha, Ayyanan Gomathi, and Dhanasekaran Suraksha. "Mangrove tree aerial root extract mediated green synthesis of Ag/Fe3O4/rGO nanocomposite and its application as a catalyst for one pot synthesis of 7-phenyl-6H,7H-benzo[4,5]imidazo[2,1-b]chromeno[4,3-d][1,3]thiazin-6-one derivatives." Environmental Science and Pollution Research, October 2, 2024. http://dx.doi.org/10.1007/s11356-024-35126-4.

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