Relevant bibliographies by topics / 6S RNA

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  1. Journal articles
  2. Dissertations / Theses
  3. Book chapters

Academic literature on the topic '6S RNA'

Author: Grafiati
Published: 4 June 2021
Last updated: 4 February 2022

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Journal articles on the topic "6S RNA"

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Trotochaud, Amy E., and Karen M. Wassarman. "6S RNA Function Enhances Long-Term Cell Survival." Journal of Bacteriology 186, no. 15 (2004): 4978–85. http://dx.doi.org/10.1128/jb.186.15.4978-4985.2004.

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ABSTRACT 6S RNA was identified in Escherichia coli >30 years ago, but the physiological role of this RNA has remained elusive. Here, we demonstrate that 6S RNA-deficient cells are at a disadvantage for survival in stationary phase, a time when 6S RNA regulates transcription. Growth defects were most apparent as a decrease in the competitive fitness of cells lacking 6S RNA. To decipher the molecular mechanisms underlying the growth defects, we have expanded studies of 6S RNA effects on transcription. 6S RNA inhibition of σ70-dependent transcription was not ubiquitous, in spite of the fact th
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Trotochaud, Amy E., and Karen M. Wassarman. "6S RNA Regulation of pspF Transcription Leads to Altered Cell Survival at High pH." Journal of Bacteriology 188, no. 11 (2006): 3936–43. http://dx.doi.org/10.1128/jb.00079-06.

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ABSTRACT 6S RNA is a highly abundant small RNA that regulates transcription through direct interaction with RNA polymerase. Here we show that 6S RNA directly inhibits transcription of pspF, which subsequently leads to inhibition of pspABCDE and pspG expression. Cells without 6S RNA are able to survive at elevated pH better than wild-type cells due to loss of 6S RNA-regulation of pspF. This 6S RNA-dependent phenotype is eliminated in pspF-null cells, indicating that 6S RNA effects are conferred through PspF. Similar growth phenotypes are seen when PspF levels are increased in a 6S RNA-independe
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Willkomm, Dagmar K., and Roland K. Hartmann. "6S RNA – an ancient regulator of bacterial RNA polymerase rediscovered." Biological Chemistry 386, no. 12 (2005): 1273–77. http://dx.doi.org/10.1515/bc.2005.144.

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AbstractThe bacterial riboregulator 6S RNA was one of the first non-coding RNAs to be discovered in the late 1960s, but its cellular role remained enigmatic until the year 2000. 6S RNA, only recognized to be ubiquitous among bacteria in 2005, binds to RNA polymerase in a σ factor-dependent manner to repress transcription from a subgroup of promoters. The common feature of a double-stranded rod with a central bulge has led to the proposal that 6S RNA may mimic an open promoter complex.
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Neußer, Thomas, Nina Gildehaus, Reinhild Wurm, and Rolf Wagner. "Studies on the expression of 6S RNA from E. coli: involvement of regulators important for stress and growth adaptation." Biological Chemistry 389, no. 3 (2008): 285–97. http://dx.doi.org/10.1515/bc.2008.023.

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AbstractThe small bacterial 6S RNA has been recognized as a transcriptional regulator, facilitating the transition from exponential to stationary growth phase by preferentially inhibiting Eσ70RNA polymerase holoenzyme transcription. Consistent with this function, the cellular concentration of 6S RNA increases with stationary phase. We have studied the underlying mechanisms responsible for the growth phase-dependent differences in 6S RNA concentration. To this aim, we have analyzed the effects of the typical bacterial growth phase and stress regulators FIS, H-NS, LRP and StpA on 6S RNA expressi
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Cavanagh, Amy T., Pete Chandrangsu, and Karen M. Wassarman. "6S RNA regulation of relA alters ppGpp levels in early stationary phase." Microbiology 156, no. 12 (2010): 3791–800. http://dx.doi.org/10.1099/mic.0.043992-0.

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6S RNA is a small, non-coding RNA that interacts directly with σ 70-RNA polymerase and regulates transcription at many σ 70-dependent promoters. Here, we demonstrate that 6S RNA regulates transcription of relA, which encodes a ppGpp synthase. The 6S RNA-dependent regulation of relA expression results in increased ppGpp levels during early stationary phase in cells lacking 6S RNA. These changes in ppGpp levels, although modest, are sufficient to result in altered regulation of transcription from σ 70-dependent promoters sensitive to ppGpp, including those promoting expression of genes involved
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Steuten, Benedikt, and Rolf Wagner. "A conformational switch is responsible for the reversal of the 6S RNA-dependent RNA polymerase inhibition in Escherichia coli." Biological Chemistry 393, no. 12 (2012): 1513–22. http://dx.doi.org/10.1515/hsz-2012-0237.

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Abstract 6S RNA is a bacterial transcriptional regulator, which accumulates during stationary phase and inhibits transcription from many promoters due to stable association with σ70-containing RNA polymerase. This inhibitory RNA polymerase~6S RNA complex dissociates during nutritional upshift, when cells undergo outgrowth from stationary phase, releasing active RNA polymerase ready for transcription. The release reaction depends on a characteristic property of 6S RNAs, namely to act as template for the de novo synthesis of small RNAs, termed pRNAs. Here, we used limited hydrolysis with structu
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Wehner, Stefanie, Katrin Damm, Roland K. Hartmann, and Manja Marz. "Dissemination of 6S RNA among Bacteria." RNA Biology 11, no. 11 (2014): 1467–78. http://dx.doi.org/10.4161/rna.29894.

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Burenina, O. Y., P. G. Hoch, K. Damm, et al. "Mechanistic comparison of Bacillus subtilis 6S-1 and 6S-2 RNAs--commonalities and differences." RNA 20, no. 3 (2014): 348–59. http://dx.doi.org/10.1261/rna.042077.113.

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Wassarman, Karen Montzka, and Gisela Storz. "6S RNA Regulates E. coli RNA Polymerase Activity." Cell 101, no. 6 (2000): 613–23. http://dx.doi.org/10.1016/s0092-8674(00)80873-9.

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Wassarman, Karen M. "6S RNA: a small RNA regulator of transcription." Current Opinion in Microbiology 10, no. 2 (2007): 164–68. http://dx.doi.org/10.1016/j.mib.2007.03.008.

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Dissertations / Theses on the topic "6S RNA"

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Schneider, Sabine [Verfasser]. "Charakterisierung zellulärer Interaktionspartner der 6S RNA aus Escherichia coli und Analyse des 6S RNA Regulationsnetzwerkes / Sabine Schneider." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2014. http://d-nb.info/1053761589/34.

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Steuten, Benedikt [Verfasser], and Joachim [Akademischer Betreuer] Ernst. "Untersuchungen zur Struktur und Funktion der bakteriellen 6S RNA und Charakterisierung der 6S RNA Wechselwirkung mit RNA-Polymerase / Benedikt Steuten. Gutachter: Joachim Ernst." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2014. http://d-nb.info/1046404520/34.

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Gildehaus, Nina. "Analysen zur Funktion und Interaktion der phasenabhängig exprimierten E. coli 6S RNA." [S.l.] : [s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=978334469.

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Martins, Ana Rita Nunes. "Purificação de RNA por cromatografia de afinidade com histidina imobilizada." Master's thesis, Universidade da Beira interior, 2009. http://hdl.handle.net/10400.6/1767.

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O recente desenvolvimento da terapia génica surge como uma nova abordagem para o potencial tratamento de doenças consideradas incuráveis. Apesar destas estratégias se terem iniciado com DNA, investigações recentes tem avaliado o potencial interesse terapêutico do RNA. No entanto, os protocolos disponível para o isolamento do RNA são limitados, morosos e requerem o uso de solventes tóxicos, o que tornam estes procedimentos inadequados para recuperar o produto a ser biologicamente aplicado. O principal objectivo deste estudo é investigar a aplicabilidade da cromatografia de afinidade com histid
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Heilmann, Beate. "Regulation der Stressadaptation in Cyanobakterien - Untersuchungen zur Funktion von 6S RNA und Sigmafaktoren." Doctoral thesis, Humboldt-Universität zu Berlin, 2019. http://dx.doi.org/10.18452/20459.

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Die hoch abundante sRNA 6S RNA reguliert in Prokaryoten durch Bildung eines stabilen Riboproteinkomplexes mit der RNA Polymerase maßgeblich die globale Genexpression zur Anpassung an wechselnde Umweltbedingungen. In der vorliegenden Arbeit wurde die regulative Funktion von 6S RNA in Cyanobakterien am Beispiel des Modellorganismus Synechocystis sp. PCC 6803 beleuchtet. Die Analysen zeigten, dass die 6S RNA-Transkriptmenge sowohl unter phototrophen als auch unter photoheterotrophen Bedingungen in der stationären Wachstumsphase abnahm. Zudem wurden physiologische Untersuchungen einer 6S RNA-Delet
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Geißen, René [Verfasser], Rolf [Akademischer Betreuer] Wagner, and Michael [Akademischer Betreuer] Feldbrügge. "Analyse der physiologischen Rolle der 6S RNA aus Escherichia coli und Vergleich der molekularen Mechanismen zwischen 6S RNAs aus E. coli und Cyanobakterien / René Geißen. Gutachter: Michael Feldbrügge. Betreuer: Rolf Wagner." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2011. http://d-nb.info/101543472X/34.

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Heilmann, Beate [Verfasser], Christian [Gutachter] Schmitz-Linneweber, Ilka Maria [Gutachter] Axmann, and Rolf [Gutachter] Wagner. "Regulation der Stressadaptation in Cyanobakterien - Untersuchungen zur Funktion von 6S RNA und Sigmafaktoren / Beate Heilmann ; Gutachter: Christian Schmitz-Linneweber, Ilka Maria Axmann, Rolf Wagner." Berlin : Humboldt-Universität zu Berlin, 2019. http://d-nb.info/1194925634/34.

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Ellis, Joseph. "The RNA world: a look at Ribonuclease P RNA, small nucleolar RNA, 6S RNA, and the small ribosomal subunit /." 2006. http://www.lib.ncsu.edu/theses/available/etd-10202006-081103/unrestricted/etd.pdf.

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Klocko, Andrew D. "Dissecting the interaction between Escherichia coli 6S RNA and the RNA polymerase sigma⁷⁰ subunit /." 2009. http://www.library.wisc.edu/databases/connect/dissertations.html.

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Burýšková, Barbora. "Vliv 6S-like RNA molekul na fyziologickou diferenciaci Streptomyces coelicolor." Master's thesis, 2018. http://www.nusl.cz/ntk/nusl-373540.

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The variety of bacteria and their genomes sometimes causes conservation of homologue molecules to be displayed not in sequence but in secondary and tertiary structures. In the case of the regulatory 6S RNA, sequence homologues have been found in over 100 bacterial species so far. However, none were found in the genus Streptomyces. The unique genome of these soil- dwelling bacteria, known for their capacity to produce antibiotics, has a high G/C content and diverges substantially from distantly related bacteria. Yet in the non-coding 6S RNA it is the secondary structure that is crucial for its
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Book chapters on the topic "6S RNA"

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Wassarman, Karen M. "6S RNA: A Regulator of Transcription." In Regulatory RNAs in Prokaryotes. Springer Vienna, 2012. http://dx.doi.org/10.1007/978-3-7091-0218-3_6.

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Wassarman, Karen M. "6S RNA, a Global Regulator of Transcription." In Regulating with RNA in Bacteria and Archaea. ASM Press, 2018. http://dx.doi.org/10.1128/9781683670247.ch20.

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Wassarman, Karen M. "Native Gel Electrophoresis to Study the Binding and Release of RNA Polymerase by 6S RNA." In Bacterial Regulatory RNA. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-949-5_17.

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"6S RNA." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_14972.

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"RNA 6S." In Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6754-9_14784.

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"6S RNA, a Global Regulator of Transcription." In Regulating with RNA in Bacteria and Archaea. American Society of Microbiology, 2019. http://dx.doi.org/10.1128/microbiolspec.rwr-0019-2018.

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