Academic literature on the topic '7-AZAINDOLE'

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Journal articles on the topic "7-AZAINDOLE"

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Belasri, Khadija, Ferenc Fülöp, and István Szatmári. "Solvent-Free C-3 Coupling of Azaindoles with Cyclic Imines." Molecules 24, no. 19 (2019): 3578. http://dx.doi.org/10.3390/molecules24193578.

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By direct coupling 7-azaindole and cyclic imines, such as 3,4-dihydroisoquinoline, 6,7-dihydrothieno[3,2-c]pyridine, 3,4-dihydro-β-carboline, and 4,5-dihydro-3H-benz[c]azepine, new 3-substituted 7-azaindole derivatives have been synthesized. The reaction was extended to 4-azaindoles and 6-azaindoles, as electron-rich aromatic compounds. The lowest reactivity was observed in the case of C-3 substitution of 5-azaindole. In this case, the aza-Friedel-Crafts reaction took place by using 10 mol % of p-toluenesulfonic acid (p-TSA) as the catalyst. The role of the acid catalyst can be explained by th
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Pan, Changduo, Yun Wang, Chao Wu, and Jin-Tao Yu. "Iridium-catalyzed C–H phosphoramidation of N-aryl-7-azaindoles with phosphoryl azides." Organic & Biomolecular Chemistry 16, no. 20 (2018): 3711–15. http://dx.doi.org/10.1039/c8ob00776d.

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Nowak, Maciej J., Igor Reva, Hanna Rostkowska, and Leszek Lapinski. "UV-induced hydrogen-atom transfer and hydrogen-atom detachment in monomeric 7-azaindole isolated in Ar and n-H2 matrices." Physical Chemistry Chemical Physics 19, no. 18 (2017): 11447–54. http://dx.doi.org/10.1039/c7cp01363a.

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Upon UV excitation, the N1H form of 7-azaindole isolated in an Ar matrix transforms into N7H, C3H tautomers and the 7-azaindolyl radical; whereas only C3H and 7-azaindolyl radical products are photogenerated in solid H<sub>2</sub> environment.
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Noble, Jennifer A., Ernesto Marceca, Claude Dedonder, and Christophe Jouvet. "Influence of the N atom and its position on electron photodetachment of deprotonated indole and azaindole." Physical Chemistry Chemical Physics 22, no. 46 (2020): 27290–99. http://dx.doi.org/10.1039/d0cp03609a.

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Chong, Delano P. "Computational Study of the Electron Spectra of Vapor-Phase Indole and Four Azaindoles." Molecules 26, no. 7 (2021): 1947. http://dx.doi.org/10.3390/molecules26071947.

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After geometry optimization, the electron spectra of indole and four azaindoles are calculated by density functional theory. Available experimental photoemission and excitation data for indole and 7-azaindole are used to compare with the theoretical values. The results for the other azaindoles are presented as predictions to help the interpretation of experimental spectra when they become available.
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Poitras, Jacques, and André L. Beauchamp. "Reactions of 7-azaindole with niobium and tantalum pentachlorides and coupling to the azaindolyl-azaindolium cation." Canadian Journal of Chemistry 72, no. 7 (1994): 1675–83. http://dx.doi.org/10.1139/v94-211.

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The reaction of NbCl5 and TaCl5 with 7-azaindole (Haza) at room temperature in benzene or dichloromethane yielded MCl5(Haza) addition compounds. Under more severe conditions, the same compound was obtained with TaCl5. For NbCl5, some reduction to Nb(IV) was observed and NbCl5(Haza), NbCl4(Haza)2, and the (H2aza)+ ion were identified in the reaction mixture by infrared spectroscopy. Oxidative coupling of two azaindole units via N7—C6 also took place during the reaction, since the 7-(azaindol-6-yl)azaindolium cation was found as counter-ion in the crystal structures of two complex salts. In the
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Dufour, Pascal, Yves Dartiguenave, Michèle Dartiguenave, et al. "Crystal structures of 7-azaindole, an unusual hydrogen-bonded tetramer, and of two of its methylmercury(II) complexes." Canadian Journal of Chemistry 68, no. 1 (1990): 193–201. http://dx.doi.org/10.1139/v90-025.

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Crystals of 7-azaindole ([Formula: see text], a = 11.312(4), b = 14.960(6), c = 15.509(5) Å, α = 102.86(3), β = 108.78(3), γ = 90.71(3)°, Z = 16, R = 0.052) contain tetrameric units of approximate S4 symmetry, in which the molecules are associated by means of four complementary N—H … N hydrogen bonds. [CH3Hg(7-azaindole)]NO3 ([Formula: see text], a = 7.818(3), b = 7.884(3), c = 9.135(4) Å, α = 97.89(3), β = 109.13(3), γ = 103.28(3)°, Z = 2, R = 0.039) contains well-separated nitrate ions and complex cations in which the methylmercury group is linearly bonded to the pyridine nitrogen atom, wher
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Decrop, Maylis, Claire Espanel, Jerome Guillard, et al. "Pyrrolo[2,3-b]Pyridinic Derivatives Induce Cell Growth Inhibition of the Myeloblastic HL-60 Cell Line." Blood 108, no. 11 (2006): 4400. http://dx.doi.org/10.1182/blood.v108.11.4400.4400.

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Abstract Cytokins, N6-subsitued adenine derivatives play an important role in many different processes in plant development (Mok et al, Annu Rev Plant. Physiol Plant Mol Biol2001, 52:89–118), including the cell growth and division control, the vegetable cell differentiation with auxin and the storage of various metabolites as alkaloids (Yahia et al, Plant Science1998, 133:9–15). Furthermore, several studies suggest that cytokinins and their purin derivated are able to control mammalian cell apoptosis and differentiation of human leukemic cells (HL-60 myeloblastic cell line) into mature granulo
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Ameur Messaoud, Mohamed Yacine Ameur, Ghenia Bentabed-Ababsa, Ziad Fajloun, et al. "Deprotometalation-Iodolysis and Direct Iodination of 1-Arylated 7-Azaindoles: Reactivity Studies and Molecule Properties." Molecules 26, no. 20 (2021): 6314. http://dx.doi.org/10.3390/molecules26206314.

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Five protocols were first compared for the copper-catalyzed C-N bond formation between 7-azaindole and aryl/heteroaryl iodides/bromides. The 1-arylated 7-azaindoles thus obtained were subjected to deprotometalation-iodolysis sequences using lithium 2,2,6,6-tetramethylpiperidide as the base and the corresponding zinc diamide as an in situ trap. The reactivity of the substrate was discussed in light of the calculated atomic charges and the pKa values. The behavior of the 1-arylated 7-azaindoles in direct iodination was then studied, and the results explained by considering the HOMO orbital coeff
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Catalán, Javier, Cristina Díaz, and José L. G. de Paz. "Excited-state proton phototransfer in the (3-methyl-7-azaindole)-(7-azaindole) heterodimer." Chemical Physics Letters 419, no. 1-3 (2006): 164–67. http://dx.doi.org/10.1016/j.cplett.2005.11.072.

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Dissertations / Theses on the topic "7-AZAINDOLE"

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PANZECA, Giovanna. "New indole and 7-azaindole derivatives as protein kinase inhibitors." Doctoral thesis, Università degli Studi di Palermo, 2023. https://hdl.handle.net/10447/580045.

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Pogozhev, Dmitry. "Sequential construction of crystalline heterometallic architectures based on 7-azaindole and dipyrrin ligands." Strasbourg, 2010. http://www.theses.fr/2010STRA6060.

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Les polymères de coordination revêtent un grand intérêt de par leurs applications potentielles dans les domaines de la catalyse ou du stockage de gaz, par exemple. Alors que la majorité des architectures décrites sont homométalliques, l'obtention de leurs analogues hétérométalliques représente un défi synthétique. En effet, une approche «one-pot)), par principe, peut mener à un mélange statistique de composés homo- et hétérométalliques. Afin de résoudre ce problème, une stratégie séquentielle a été mise au point. Elle repose sur l'utilisation de ligands portant des pôles de coordination différ
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Couhert, Audrey. "Conception de ligands mixtes mélatoninergiques et sérotoninergiques à structure azaindolique et furopyridinique." Thesis, Orléans, 2015. http://www.theses.fr/2015ORLE2008/document.

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La mélatonine est une neurohormone sécrétée en période nocturne dans la glande pinéale. Elle régule les rythmes biologiques et influe sur différents processus physiologiques. Son implication ainsi que celle de la sérotonine, un neurotransmetteur, dans certains troubles de l’humeur font des récepteurs associés à ces deux hormones (MT1, MT2 et 5-HT2C respectivement) des cibles innovantes pour le développement de nouveaux antidépresseurs. Dans le cadre de cette thèse, des ligands mixtes mélatoninergiques et sérotoninergiques en série 7-azaindolique ont été synthétisés et testés biologiquement. L’
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Zhou, Qingqing. "Design Synthesis and Biological Evaluation of DYRK1A Inhibitors." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/17716.

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DYRK1A is a dual-specificity protein kinase that catalyses not only autophosphorylation on its tyrosine residue but the phosphorylation of serine and threonine residues in its substrates. DYRK1A has been shown to be important for phosphorylation of tau protein and has also been identified as a Down syndrome candidate gene. DYRK1A overexpression has also been found in cancer cells, particularly in glioblastoma, which represents 15% of brain tumours. The increased phosphorylation of sprouty2 mediated by DYRK1A blocks the EGFR degradation as a result of overexpression of EGFR in the cell surface,
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Wu, Qingguo. "Luminescent organic and organometallic compounds based on 7-azaindole, 2,2'-dipyridylamine, 8-hydroxyquinoline and derivatives and their electroluminescent applications." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0010/NQ52866.pdf.

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Bronner, Catherine. "Complexes cyclométallés coordinants pour la construction d'assemblages hétérométalliques." Strasbourg, 2010. https://publication-theses.unistra.fr/public/theses_doctorat/2010/BRONNER_Catherine_2010.pdf.

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L’utilisation de composés moléculaires coordinants et modulables (nature, nombre, différenciation et disposition des sites de coordination) pour la construction séquentielle de matériaux ou d’assemblages moléculaires finis offre de nombreuses possibilités conceptuelles et synthétiques. Les complexes métalliques sont en particulier de très intéressantes briques de construction en raison de la diversité de leurs propriétés physiques ajustables (magnétique, optique, électrochimique). Nous nous sommes intéressés plus particulièrement au cours de ce travail à l’utilisation de fragments cyclométallé
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Donati, Ludovic. "L' unité ortho-bromobenzamide : étude de la réactivité en couplage organopalladié et application à la synthèse de pyridopyrroloisoquinolones et de phénanthridinones à potentialité thérapeutique." Paris 5, 2010. http://www.theses.fr/2010PA05P636.

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Ce projet se place dans le cadre de la préparation de nouveaux composés antitumoraux, analogues de la fagaronine et de la nitidine, alcaloïdes naturels inhibiteurs de la topoisomérase I. Les nouvelles structures envisagées sont de type pyridopyrroloisoquinolones et pyridopyrroloquinolones. Les stratégies de synthèse mises en oeuvre ont conduit à la formation de nouveaux produits possédant une structure tétracyclique ou tricyclique inattendues. Afin de comprendre la réactivité du motif orthobromobenzamide en pallado-catalyse, la formation des dérivés tricycliques a fait l'objet d'une étude méca
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Le, Fouler Vincent. "Etude de la réactivité des pyrimidines dans des réactions de Diels-Alder à demande électronique inverse." Thesis, Strasbourg, 2019. http://www.theses.fr/2019STRAF022.

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La séquence ihDA/rDA est une transformation d’intérêt en synthèse organique en raison de la complexité structurelle à laquelle elle donne accès facilement. A ce jour l’utilisation des pyrimidines dans de telles séquences est encore peu explorée en raison de leur faible réactivité. Dans ce manuscrit sont décrites deux stratégies impliquant des pyrimidines dans une séquence ihDA/rDA pour la synthèse de 4-azaindolines et de 7-azaindazoles. Dans le cadre de la synthèse des 4-azaindolines, les travaux rapportés se concentrent sur la synthèse d’une série d’intermédiaires clés de la synthèse des 4-az
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Rost, Ulrike. "Organisation and Recognition of Artificial Transmembrane Peptides." Doctoral thesis, Niedersächsische Staats- und Universitätsbibliothek Göttingen, 2016. http://hdl.handle.net/11858/00-1735-0000-002B-7CA6-D.

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Drießen, Daniel [Verfasser], Thomas J. J. [Gutachter] Müller, and Jörg [Gutachter] Pietruszka. "Diversitätsorientierte Synthese neuer 7-Azaindol-Derivate gegen Therapie-resistente Tumore und Infektionen / Daniel Drießen ; Gutachter: Thomas J.J. Müller, Jörg Pietruszka." Düsseldorf : Universitäts- und Landesbibliothek der Heinrich-Heine-Universität Düsseldorf, 2020. http://d-nb.info/1212238699/34.

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Book chapters on the topic "7-AZAINDOLE"

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Négrerie, M., F. Gai, J. C. Lambry, J. L. Martin, and J. W. Petrich. "Excited-State Processes of 7-Azaindole." In Ultrafast Phenomena VIII. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-84910-7_200.

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Nakajima, A., Y. Negishi, R. Hasurni, and K. Kaya. "Photoelectron spectroscopy of 7-azaindole—water cluster anions." In The European Physical Journal D. Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-642-88188-6_57.

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Redondo, Carmen M., and David C. Clary. "Femtodynamics of Double Proton Transfer in 7-azaindole Dimer." In Lecture Notes in Chemistry. Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-57051-3_22.

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Gai, F., R. L. Rich, Y. Chen, and J. W. Petrich. "Probing Solvation by Alcohols and Water with 7-Azaindole." In Structure and Reactivity in Aqueous Solution. American Chemical Society, 1994. http://dx.doi.org/10.1021/bk-1994-0568.ch013.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of niobium(IV) tetrachloride adduct of 7-azaindole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-49202-4_420.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of copper(II) chloride adduct of 7-azaindole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_12.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of chloro-copper(II) complex of 7-azaindole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_13.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of chloro-oxo-copper(II) complex of 7-azaindole." In Magnetic Properties of Paramagnetic Compounds. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-53974-3_14.

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Pardasani, R. T., and P. Pardasani. "Magnetic properties of chloro-bridged copper(II) complex with 7-azaindole." In Magnetic Properties of Paramagnetic Compounds, Magnetic Susceptibility Data, Volume 6. Springer Berlin Heidelberg, 2022. http://dx.doi.org/10.1007/978-3-662-65056-1_485.

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Chapman, C. F., T. J. Marrone, R. S. Moog, and M. Maroncelli. "Excited-State Proton Transfer and Hydrogen-Bonding Dynamics in 7-Azaindole: Time-Resolved Fluorescence and Computer Simulation." In Ultrafast Phenomena VIII. Springer Berlin Heidelberg, 1993. http://dx.doi.org/10.1007/978-3-642-84910-7_201.

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Conference papers on the topic "7-AZAINDOLE"

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CARD, D. A., D. E. FOLMER, E. S. WISNIEWSKI, and A. W. CASTLEMAN. "COVARIANCE MAPPING STUDIES OF 7-AZAINDOLE FRAGMENTS." In Proceedings of the International Symposium. WORLD SCIENTIFIC, 2000. http://dx.doi.org/10.1142/9789812793805_0003.

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Rich, R. L., F. Gai, Yeh F. Chen, and Jacob Petrich. "Using 7-azaindole to probe condensed phase dynamics." In OE/LASE '94, edited by Joseph R. Lakowicz. SPIE, 1994. http://dx.doi.org/10.1117/12.182753.

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Chapman, C. F., T. J. Marrone, R. S. Moog, and M. Maroncelli. "Excited-State Proton Transfer and Hydrogen-Bonding Dynamics in 7-Azaindole: Time-Resolved Fluorescence and Computer Simulation." In International Conference on Ultrafast Phenomena. Optica Publishing Group, 1992. http://dx.doi.org/10.1364/up.1992.fc6.

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7-Azaindole (7AI) is one of a class of molecules that exhibit dual fluorescence as a result of excited-state tautomer formation. The tautomer is reached through a proton transfer from the initially excited "normal" form, the only form present in the ground electronic state. When isolated (in the gas phase or in non-hydroxylic solvents) 7AI does not tautomerize at an observable rate. However, in non-polar solvents, 7-azaindole forms dimers which enable the excited-state tautomerization to occur via a double proton transfer mechanism. Tautomerization in 7AI dimers has been studied for quite some
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MORENO, MIQUEL, JOSÉ MARÍA LLUCH, and ABDERRAZZAK DOUHAL. "THE 7-AZAINDOLE BASE PAIR PHOTOTAUTOMERIZATION REVISITED: AN AB INITIO STUDY OF THE POTENTIAL ENERGY SURFACE." In With Foreword by Prof A H Zewail, Nobel Laureate in Chemistry, 1999. WORLD SCIENTIFIC, 2002. http://dx.doi.org/10.1142/9789812777980_0079.

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