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Relevant bibliographies by topics / 7-chloroquinoline

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Journal articles

Academic literature on the topic '7-chloroquinoline'

Author: Grafiati

Published: 4 May 2022

Last updated: 5 May 2022

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Journal articles on the topic "7-chloroquinoline"

1

Arsanious, Mona, Shaban Darwish, El-Sayed Shalaby, and Dina El-Ghwas. "Synthesis, X-ray, DFT Studies and Antimicrobial Properties of New Quinolinylphosphonates." Letters in Organic Chemistry 16, no. 8 (2019): 668–75. http://dx.doi.org/10.2174/1570178616666181231161801.

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The phosphorus atom in hexamethyl phosphorus triamide 5 attacks the carbonyl function in 2-chloroquinoline-3-carbaldehyde 4a to give the bis-quinolinyl ethanone product 6. On the other hand, quinoline ring-attack proceeds by the same phosphorus reagent upon reaction with 2-chloroquinoline- 3-aldoxime 4b yielding phosphonate 7. Meanwhile, the reaction of the tris-aminophosphine reagent 5 with 2-chloroquinoline- 3-(p-chlorophenyl)imine 4c affords the respective α-aminophosphonate 8. Moreover, the attack by phosphine 5 on 2-chloroquinoline-3-imines 4d and 4e produces the respective cyclic azophos

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2

Motiwala, Hashim F., Raj Kumar, and Asit K. Chakraborti. "Microwave-Accelerated Solvent- and Catalyst-Free Synthesis of 4-Aminoaryl/alkyl-7-chloroquinolines and 2-Aminoaryl/alkylbenzothiazoles." Australian Journal of Chemistry 60, no. 5 (2007): 369. http://dx.doi.org/10.1071/ch06391.

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An efficient synthesis of 4-aminoaryl/alkyl-7-chloroquinolines and 2-aminoaryl/alkylbenzothiazoles has been developed by microwave-accelerated regioselective aromatic nucleophilic substitution of 4,7-dichloroquinoline and 2-chlorobenzothiazole with aromatic and aliphatic amines under solvent-free conditions in the absence of any added protic or Lewis acid catalyst. Chemoselective reaction with the amino group in preference to the phenolic hydroxy group was observed. Thus, the treatment of 4,7-dichloroquinoline (1 equiv.) with a mixture of aniline (2 equiv.) and phenol (2 equiv.) afforded exclu

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3

Le, Trong Duc, Ngoc Nam Pham, and Tien Cong Nguyen. "Preparation and Antibacterial Activity of Some New 4-(2-Heterylidenehydrazinyl)-7-chloroquinoline Derivatives." Journal of Chemistry 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/4301847.

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N-(4-Substituted phenyl)acetamides, which were prepared from acetic anhydride and p-substituted anilines, were utilized as precursors for reactions to Vilsmeier-Haack reagent to form 6-substituted-2-chloroquinoline-3-carbaldehydes 3a–c. Meanwhile, a similar reagent was applied to 1-[1-(4-substituted phenyl)ethylidene]-2-phenylhydrazines as substrates, which were synthesized from phenylhydrazine hydrochloride and p-substituted acetophenones, and 1,3-diarylpyrazole-4-carbaldehydes 3d–f were observed as a result. Reactions between the aldehydes 3a–f and 7-chloro-4-hydrazinylquinoline 2, obtained

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4

Barlin, GB, SJ Ireland, TMT Nguyen, B. Kotecka, and KH Rieckmann. "Potential Antimalarials. XVIII. Some Mono- and Di-Mannich Bases of 3-[7-Chloro(and trifluoromethyl)quinolin-4-ylamino]phenol." Australian Journal of Chemistry 46, no. 11 (1993): 1685. http://dx.doi.org/10.1071/ch9931685.

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Syntheses are reported for mono- and di-Mannich base derivatives of 3-[7-chloro(and trifluoro-methyl)quinolin-4-ylamino]phenols by Mannich reaction on 3-[7-chloro(and trifluoromethyl )-quinolin-4-ylamino]phenols or by condensation of Mannich base derivatives of 3-aminophenol, prepared from 3-nitrophenol, with the appropriate 4-chloroquinoline. The antimalarial activity of 3-(7′-chloroquinolin-4′-ylamino)-2,6-bis[ pyrrolidin-1″-ylmethyl -(or piperidin-1″-ylmethyl)]phenol against the FC-27 isolate of Plasmodium falciparum was comparable to that of chloroquine, and it was not significantly dimini

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5

Yanni, Amal S., and Zarif H. Khalil. "Synthesis of some new 7-substituted aminomethyl-6-chloroquinoline-5,8-quinone." Collection of Czechoslovak Chemical Communications 56, no. 3 (1991): 702–5. http://dx.doi.org/10.1135/cccc19910702.

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6

Raj, Raghu, Anu Saini, Jiri Gut, Philip J. Rosenthal, and Vipan Kumar. "Synthesis and in vitro antiplasmodial evaluation of 7-chloroquinoline–chalcone and 7-chloroquinoline–ferrocenylchalcone conjugates." European Journal of Medicinal Chemistry 95 (May 2015): 230–39. http://dx.doi.org/10.1016/j.ejmech.2015.03.045.

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7

Yanni, Amal S., Zarif H. Khalil, and Ahmed A. Timmawy. "Synthesis of some new sulfonamide derivatives of 7-chloroquinoline-5,8-dione and pyridocarbazolediones." Collection of Czechoslovak Chemical Communications 56, no. 7 (1991): 1489–94. http://dx.doi.org/10.1135/cccc19911489.

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Interaction of 6-chloroquinoline-5,8-dione hydrochloride (I) or 6,7-dichloroquinoline-5,8-dione (II) with sulfa drug in ethanol containing diethylaniline afforded 7-substituted sulfonamide-10H-pyrido[3,2-b]carbazole-5,11-dione (III), and sulfonamide derivatives of 7-chloroquinoline-5,8-diones (IV). Moreover the reaction of II with arylamine in pyridine afforded substituted 6H-pyrido[2,3-b]carbazole-5,11-dione (V). The structure of the compounds was determined by elemental and spectral analysis, and by chemical reaction.

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8

Raj, Raghu, Jiri Gut, Philip J. Rosenthal, and Vipan Kumar. "1H-1,2,3-Triazole-tethered isatin-7-chloroquinoline and 3-hydroxy-indole-7-chloroquinoline conjugates: Synthesis and antimalarial evaluation." Bioorganic & Medicinal Chemistry Letters 24, no. 3 (2014): 756–59. http://dx.doi.org/10.1016/j.bmcl.2013.12.109.

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9

Devi, Kavita, Yumna Asmat, Sonika Jain, Swapnil Sharma, and Jaya Dwivedi. "An Efficient Approach to the Synthesis of Novel Oxazolidinones as Potential Antimicrobial Agents." Journal of Chemistry 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/252187.

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Oxazolidinone, either mononuclear or condensed with other heterocyclics, has established its importance in medicinal chemistry. A variety of biological activities have been reported by oxazolidinone derivatives. The present work describes the synthesis of several oxazolidinone derivatives, 3-(2-(7-chloroquinoline-4-ylamino)ethyl)-2-imino-5-(4-chloro/nitro/methoxy benzylidene)oxazolidin-4-one 4(a–c) and 4-(2-(7-chloroquinolin-4-ylamino)ethyl)-2(4-chloro/nitro/methoxy-benzylidene)-1,6-diox-4,9-di-azaspiro[4,4]nonane-3,8-dione 5(a–c). Synthesized compounds (1, 3, 4a, 5a, and 5c) were screened aga

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10

Bueno, Juan, Fernando A. Rojas Ruiz, Santiago Villabona Estupinan, and Vladimir V. Kouznetsov. "In Vitro Antimycobacterial Activity of New 7-Chloroquinoline Derivatives." Letters in Drug Design & Discovery 9, no. 2 (2012): 126–34. http://dx.doi.org/10.2174/157018012799079761.

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