Academic literature on the topic '7-hydroxycoumarins'

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Journal articles on the topic "7-hydroxycoumarins"

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Traven, Valery F., Larisa I. Vorobjeva, Tatjana A. Chibisova, Edward Andrew Carberry, and Noelle Jean Beyer. "Electronic absorption spectra and structure of hydroxycoumarin derivatives and their ionized forms." Canadian Journal of Chemistry 75, no. 4 (1997): 365–76. http://dx.doi.org/10.1139/v97-042.

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Electronic absorption spectra of 18 hydroxycoumarin derivatives and their ionized forms have been studied. Close agreement between experimental and the PPP CI calculated electron absorption band energies has been found in most cases. Strong polarization of the carbonyl function of the pyrone ring in the 7-hydroxycoumarin derivatives, H-bonding between the hydroxyl group and neighboring substituent in the ortho-substituted hydroxycoumarins, as well as their tautomeric transformations, have been suggested in the discussion of the electronic absorption spectra of the hydroxycoumarin derivatives.
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ALOK, KUMAR MITRA, DE APARNA, KARCHAUDHURI NILAY, KUMAR MISRA SWAPAN, and KUMAR MUKHOPADHYAY APURBA. "Synthesis of Coumarins in Search of Better Nonpeptidic HIV Protease Inhibitors." Journal of Indian Chemical Society Vol. 75, Oct-Dec 1998 (1998): 666–71. https://doi.org/10.5281/zenodo.5916038.

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Department of Chemistry, University of Calcutta, 92, Acharya Prafulla Chandra Road, Calcutta-700 009 <em>Manuscript received 7 August 1998</em> 3-Substituted-4-hydroxycoumarins have been recently identified as active nonpeptidic HIV protease inhibitors. In order to get more potent inhibitors, synthesis of a number of 3-substituted-4-hydroxycoumarins have been designed. Nucleophilicity of C-3 in 4- hydroxycoum arin is exploited by reacting with an electrophile 3-carbethoxycoumarin to achieve a new C-3 substituted-4-hydroxycoumarin. But the product identified is a benzopyranodicoumarin (2), whic
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Huitink, Geraldine M. "Studies of 7-hydroxycoumarins." Talanta 35, no. 12 (1988): 973–76. http://dx.doi.org/10.1016/0039-9140(88)80231-5.

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Datta, Mrityunjoy. "Synthesis of Linear 6-Allylated-7-hydroxycoumarins: para-Claisen Rearrangement of 2'-Allylated/Prenylated Derivatives of 4'-Prenyloxy Cinnamic Acid." Asian Journal of Chemistry 37, no. 1 (2024): 100–104. https://doi.org/10.14233/ajchem.2025.32937.

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Linear 6-allylated-7-hydroxycoumarins were synthesized by the para-Claisen rearrangement of 4'-prenyloxy cinnamic acid derivatives under refluxing condition in N,N-diethylaniline. This method eliminates the requirement for an additional Lewis acid, such as boron trifluoride etherate or trichloride, to convert 7-alkoxycoumarins into 7-hydroxycoumarins, unlike alternative techniques.
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Bondarenko, S. P., M. S. Frasinyuk, and V. P. Khilya. "Aminomethylation of 3-aryl-7-hydroxycoumarins." Chemistry of Heterocyclic Compounds 46, no. 5 (2010): 529–35. http://dx.doi.org/10.1007/s10593-010-0541-y.

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Timonen, Juri, Paula Aulaskari, Pipsa Hirva, and Pirjo Vainiotalo. "Negative Ion Electrospray Ionization Mass Spectrometry and Computational Studies on Substituted 7-Hydroxycoumarins." European Journal of Mass Spectrometry 15, no. 5 (2009): 595–603. http://dx.doi.org/10.1255/ejms.1019.

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Twenty-two substituted 7-hydroxycoumarins were studied by negative ion electrospray ionization collision-induced dissociation (CID) mass spectrometry. Fragmentation pathways were also investigated by computation method using the B3LYP density functional theory. In general, the most important fragmentations of the 7-hydroxycoumarin [M – H]− ions were the elimination of CO2 and CO which agreed with the calculated energies of the proposed fragmentation reactions. In most cases, methyl group elimination was also favorable. Methyl group elimination occurred in three different ways, the most interes
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Smith, Gerald J., Roderick J. Weston, Ying Tang, Yinrong Lu, and Jolon M. Dyer. "Photoproducts of 7-Hydroxycoumarins in Aqueous Solution." Australian Journal of Chemistry 65, no. 10 (2012): 1451. http://dx.doi.org/10.1071/ch12292.

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Near-UV irradiation of aqueous solutions of 7-hydroxy-6-methoxycoumarin (scopoletin) and 6,7-dihydroxycoumarin (esculetin) resulted in the formation of dimers. Substantially greater amounts of the 7-hydroxy-6-methoxycoumarin photodimer were produced compared with that of 6,7-dihydroxycoumarin. Fluorescence spectra indicated that the initial photolytic reaction involves the excited state of the phenolate form of the monomeric coumarin. The electro-spray ionization (ESI) mass spectrum suggested that the major product (with a sodiated quasimolecular ion at m/z 405) from the photolysis of scopolet
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Liu, Chang-Ling, Miao Li, Ai-Ying Guan, Hong Zhang, and Zheng-Ming Li. "Design, Synthesis and Fungicidal Activity of Novel (E)-Methyl 2-{2-[(coumarin-7-yloxy)methyl]phenyl}-3-methoxyacrylates." Natural Product Communications 2, no. 8 (2007): 1934578X0700200. http://dx.doi.org/10.1177/1934578x0700200811.

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A number of 7-hydroxycoumarins (5), on treatment with one equivalent of ( E)-methyl 2-{2-[(chloromethyl)phenyl]}-3-methoxyacrylate (6) at 80°C for 6–8 h, afforded ( E)-methyl 2-{2-[(coumarin-7-yloxy)methyl]phenyl}-3-methoxyacrylates (2) in 80–85% yields. The 7-hydroxycoumarins (5) were in turn prepared from resorcinols (3) and substituted ethyl 3-oxopropanoate (4). Subsequently, results of biological activities evaluated in the greenhouse indicated that several of these compounds have good fungicidal activity against cucumber downy mildew (CDM) at 25g ai/ha.
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Rashid, Mohammad A., James A. Armstrong, Alexander I. Gray, and Peter G. Waterman. "Novel C-Geranyl 7-Hydroxycoumarins from the Aerial Parts of Eriostemon tomentellus." Zeitschrift für Naturforschung B 47, no. 2 (1992): 284–87. http://dx.doi.org/10.1515/znb-1992-0221.

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From the aerial parts of Eriostemon tomentellus five coumarins have been isolated. These have been characterized as ostruthin (6-geranyl-7-hydroxycoumarin (1)) and the novel compounds, 8-geranyl-7-hydroxycoumarin (2), (E)-6-(7-hydroxy-3,7-dimethylocta-2,5-dienyl)- 7-hydroxycoumarin (3), (E)-6-(7-hydroperoxy-3,7-dimethylocta-2,5-dienyl)-7-hydroxycoumarin (4), and 6-(6-hydroxy-3,7-dimethylocta-2,7-dienyl)-7-hydroxycoumarin (5). In addition tembamide (2-{4-methoxyphenyl}-2-hydroxy-N-benzoylethylamine (6 ) was isolated and the l3C NMR spectrum reported for the first time.
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Abrams, Barny. "Mono-Chlorinated 3-Carboxy-7-Hydroxycoumarin: A Highly Fluorescent and Water-Soluble Violet Excitable Dye for Cell Analysis." Blood 112, no. 11 (2008): 4929. http://dx.doi.org/10.1182/blood.v112.11.4929.4929.

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Abstract In our search for new violet excitable dyes with improved photochemical properties, we examined several halogen substituted 7-hydroxycoumarins and found that chlorinated derivatives could be as bright as their fluorinated analogs. In particular, mono-chlorinated 3-carboxy-7-hydroxycoumarin (V450) has a quantum yield equal to 3-carboxy-6,8- difluoro-7-hydroxycoumarin (Pacific Blue™). Antibodies specific to various cell surface markers (CD3, CD4, CD45) were labeled with V450 and tested in single color flow cytometry assays. Our results show that conjugates of V450 are brighter than the
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Dissertations / Theses on the topic "7-hydroxycoumarins"

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Lee, Lin-Wen, and 李玲玟. "Synthesis and antibacterial activities evaluation of 7-hydroxycoumarin and coumarin-3-carboxamide derivatives." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/00138070825567486921.

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碩士<br>臺北醫學大學<br>藥學系<br>92<br>Synthesis and antibacterial activities evaluation of 7-hydroxycoumarin and coumarin-3-carboxamide derivatives Coumarin is widely distributed in plants and the coumarin derivatives are used as fluorescence dye, laser dye, food additives and medicines at present. Nowadays coumarins are an important group of organic compounds that are used as anticoagulant (dicoumarol), antiviruses, antibacterial, antifungi, antitumor, antimutagenic, anti-inflammatory and antioxidant agents. It also use as prodrug in cartilage explants. The major metab
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"Protein Design and Engineering Using the Fluorescent Non-canonical Amino Acid L-(7-hydroxycoumarin-4-yl)ethylglycine." Doctoral diss., 2020. http://hdl.handle.net/2286/R.I.63009.

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abstract: Proteins are, arguably, the most complicated molecular machines found in nature. From the receptor proteins that decorate the exterior of cell membranes to enzymes that catalyze the slowest of chemical reactions, proteins perform a wide variety of essential biological functions. A reductionist view of proteins as a macromolecular group, however, may hold that they simply interact with other chemical species. Notably, proteins interact with other proteins, other biological macromolecules, small molecules, and ions. This in turn makes proteins uniquely qualified for use technological u
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Chen, Tzu Chun, and 陳姿均. "Ultrafast time-resolved fluorescence studies of Excited-State Proton Transfer Dynamics in 3-cyano-4-methyl-7-hydroxycoumarin complexes." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/67587882491110745079.

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碩士<br>國立清華大學<br>化學系<br>104<br>We employed a broadband ultrafast time-resolved fluorescence (TRFL) spectrometer implemented by optical Kerr gating (OKG) to study the excited-state proton transfer (ESPT) dynamics in 3-cyano-4-methyl-7-hydroxycoumarin (3CN4MU) complexes. We chose 3CN4MU as the proton donor and two bases, triethylamine (TEA) and 1-methylimidazole (1MI), of different proton affinities (PA) as the proton acceptors. We used two solvents, ethyl acetate (EA) and toluene (TL), of different polarities to study the solvent effect in ESPT. It was conclude from by steady-state spectra that
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Wu, Nien-Hsun, and 吳念勳. "Excited-State Proton Transfer Reaction in 3-Cyano-4-Methyl-7-Hydroxycoumarin Complexes Studied by Femtosecond Time-resolved Fluorescence Spectroscopy." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/6xbce8.

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碩士<br>國立清華大學<br>化學系所<br>105<br>We studied intermolecular excited-state proton transfer (ESPT) dynamics in hydrogen-bonded complexes of 3-cyano-4-methyl-7-hydroxycoumarin (3CN4MU) by using steady-state absorption/fluorescence spectroscopy and ultrafast time-resolved optical Kerr gating fluorescence spectroscopy. Two different proton acceptors, 1-methyl imidazole (1MI) and triethylamine (TEA), were studied, and the experiments were carried out in strong- and weak-polarity solvents. We also carried out density-functional-theory (DFT) calculations to help us interpreting the experimental results.
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Periasamy, Mangayarkarasi. "In Vivo Labeling Of A Model β-Clam Protein With A Fluorescent Amino Acid". 2010. https://scholarworks.umass.edu/theses/481.

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Proteins can be labeled with different tags to enable their structural and functional investigations. In addition, labeling proteins at specific sites helps in studying the conformational dynamics of these molecules. A plethora of methods is available to facilitate labeling, choice of which largely depends on the requirements and the anticipated end results. In general, the various labeling methods can be classified into four different classes based on the stage at which labeling is performed, namely post translational labeling, non-ribosomal synthesis, in vitro translation and in vivo transla
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Huang, Chin-Neng, and 黃志能. "Part I、Design and synthesis of 3-(2-Phenyl-4H-thio-chromen-4-yildene)-3H-chromene-2,4-dione derivatives as potential redox switchesPart II、Design and Synthesis of 7-N,N-dimethylamino-4-hydroxycoumarin-based derivatives as potential organic photochromi." Thesis, 2007. http://ndltd.ncl.edu.tw/handle/33645529616308159980.

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碩士<br>東海大學<br>化學系<br>95<br>Part I、Design and synthesis of 2'-phenyl-[3,4']bichromenylidene -2,4-dione derivatives as potential redox switching Tow 3-(2-Phenyl-4H-thiochromen-4-yildene)-3H-chromene-2,4-dione derivatives were synthesized in several steps from thiophenol and 4-hydroxycoumarins with overall yields of 65 and 67%. The prepared compounds 16 and 21 instantly changed from either purple or bule to colorless when treated them with sodium borohydride in methanol. The resulting reduced compounds reverted to their original colors after the reducing agent was removed. While no fluorescence
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Book chapters on the topic "7-hydroxycoumarins"

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Gainor, J. A., T. D. Gordon, and B. A. Morgan. "The synthesis and coupling efficiency of 7-hydroxycoumarin-4-propionic acid, a fluorescent marker useful in immobilized substrate libraries." In Peptides. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-011-0683-2_333.

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"3-Cyano-7-hydroxycoumarin (3-Cyanoumbelliferone)." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch54.

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"4-Heptadecyl-7-hydroxycoumarin (4-Heptadecylumbelliferone)." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch82.

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"7-Hydroxycoumarin-3-carboxylic acid succinimidyl ester." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch88.

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"Pacific Blue (6,8-Difluoro-7-hydroxycoumarin-3-carboxylic acid)." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch115.

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"7-Hydroxycoumarin-3-carboxylic acid (Umbelliferone-3-carboxylic acid)." In Handbook of Fluorescent Dyes and Probes. John Wiley & Sons, Inc, 2015. http://dx.doi.org/10.1002/9781119007104.ch87.

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MORIYA, Tetsuo, and Yoshihisa KAWAGUCHI. "AB INITIO MO CALCULATION OF THE STRUCTURE AND ENERGY LEVELS OF 7-HYDROXYCOUMARIN AND ITS TAUTOMER." In Computer Aided Innovation of New Materials. Elsevier, 1991. http://dx.doi.org/10.1016/b978-0-444-88864-8.50109-6.

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Conference papers on the topic "7-hydroxycoumarins"

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Kopylova, T. N., L. G. Samsonova, R. M. Gadirov, V. P. Khilya, V. V. Ishchenko, and O. V. Shablykina. "The nature of the photoprocesses in the new 7-hydroxycoumarines." In Atomic and Molecular Pulsed Lasers VII, edited by Victor F. Tarasenko. SPIE, 2007. http://dx.doi.org/10.1117/12.785624.

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