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1

Neumann, Julie A., Christopher M. Klein, Carola F. van Eck, Hithem Rahmi, and John M. Itamura. "Outcomes After Dermal Allograft Reconstruction of Chronic or Subacute Pectoralis Major Tendon Ruptures." Orthopaedic Journal of Sports Medicine 6, no. 1 (2018): 232596711774583. http://dx.doi.org/10.1177/2325967117745834.

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Background: Avoiding delay in the surgical management of pectoralis major (PM) ruptures optimizes outcomes. However, this is not always possible, and when a tear becomes chronic or when a subacute tear has poor tissue quality, a graft can facilitate reconstruction. Purpose: The primary aim was to evaluate the clinical outcomes of PM reconstruction with dermal allograft augmentation for chronic tears or for subacute tears with poor tissue quality. A second aim was to determine patient and surgical factors affecting outcome. Study Design: Case series; Level of evidence, 4. Methods: Nineteen cons
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Yi, Yehyeon, Da-Hye Kim, Eun-Joo Choi, Sang-Bum Hong, and Dong Kyu Oh. "The effect of a dedicated intensivist staffing to a medical emergency team on airway management in general wards." Medicine 103, no. 25 (2024): e38571. http://dx.doi.org/10.1097/md.0000000000038571.

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Although medical emergency teams (METs) have been widely introduced, studies on the importance of a dedicated intensivist staffing to METs are lacking. A single-center retrospective before-and-after study was performed. Deteriorating patients who required emergency airway management in general wards by MET were included in this study. We divided the study period according to the presence of a dedicated intensivist staff in MET: (1) non-staffed period (from January 2016 to February 2018, n = 971) and (2) staffed period (from March 2018 to December 2019, n = 651), and compared emergency airway m
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3

Steen, R. W. J. "A comparison of wheat and barley as supplements to grass silage for finishing beef cattle." Animal Science 56, no. 1 (1993): 61–67. http://dx.doi.org/10.1017/s0003356100006164.

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AbstractTwo randomized-block experiments were carried out to examine the relative value of wheat and barley as supplements to grass silage for finishing beef cattle. In each experiment unwilted, formic acid-treated silage was offered ad libitum and supplemented with 500 g soya-bean meal and 50 g minerals and vitamins to 44 12-month-old bulls for 157 and 172 days in experiments 1 and 2 respectively. Twelve of the animals also received 2·5 kg rolled spring barley (LB), 12 received 4·0 kg barley (HB) and 20 received 3·25 kg rolled wheat (W). For experiments 1 and 2 respectively the barley contain
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Rossi, Davide, Marco Fangazio, Lorenzo De Paoli, et al. "Beta-2-Microglobulin Is An Independent Predictor of Progression in Asymptomatic Multiple Myeloma." Blood 114, no. 22 (2009): 1796. http://dx.doi.org/10.1182/blood.v114.22.1796.1796.

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Abstract Abstract 1796 Poster Board I-822 The rationale of the study stems from three considerations: i) to date, few clinical predictors of asymptomatic multiple myeloma (MM) progression are available; ii) no study has assessed the role of beta-2-microglobulin (B2M) on risk of asymptomatic MM progression; iii) B2M is a serum marker of tumor burden and represents a key variable of the ISS staging system for symptomatic MM. The study aims at assessing the impact of B2M on risk of asymptomatic MM progression. The study was based on a consecutive series of 148 asymptomatic MM diagnosed according
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Lima, Bruce M., Rafael S. Amancio, Diacre S. Gonçalves, Alexander J. Koch, Victor M. Curty, and Marco Machado. "Planned Load Reduction Versus Fixed Load: A Strategy to Reduce the Perception of Effort With Similar Improvements in Hypertrophy and Strength." International Journal of Sports Physiology and Performance 13, no. 9 (2018): 1164–68. http://dx.doi.org/10.1123/ijspp.2018-0072.

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Purpose: To compare muscle thickness and 10-repetition maximum (10RM) between no load reduction and load reductions during 16 wk of resistance training. Methods: A total of 21 moderately trained men (age 23.2 [4.2] y, body mass 75.1 [7.6] kg, height 175 [4] cm) were randomized into 1 of 3 exercise groups: control (CON, n = 7), all sets with 10RM load; 5% load reduction (RED 5, n = 7); and 10% load reduction (RED 10, n = 7) for set 2 and set 3. The resistance training program consisted of completing 3 sets each of biceps and Scott curls, performed to volitional fatigue 3 d·wk−1. Results: Volume
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Krishnamoorthy, Vignesh P., Kyle N. Kunze, Edward C. Beck, et al. "Radiographic Prevalence of Symphysis Pubis Abnormalities and Clinical Outcomes in Patients With Femoroacetabular Impingement Syndrome." American Journal of Sports Medicine 47, no. 6 (2019): 1467–72. http://dx.doi.org/10.1177/0363546519837203.

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Background: The decreased hip range of motion seen in femoroacetabular impingement syndrome (FAIS) may lead to compensatory increased motion at the symphysis pubis (SP) with resultant increased stress on the joint, which can subsequently lead to osteitis pubis. Purpose: To quantify the prevalence of SP abnormalities in patients with FAIS through the use of imaging modalities and to compare outcomes based on the presence of SP abnormalities. Study Design: Cohort study; Level of evidence, 3. Methods: Radiographs and magnetic resonance imaging (MRI) scans of 1009 consecutive patients who underwen
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Morgan, C. A., A. B. Lawrence, E. A. Hunter, and J. D. Oldham. "Effect of meal frequency and rate of nutrient supply on the post-feeding behaviour of the pig." Animal Science 61, no. 3 (1995): 565–73. http://dx.doi.org/10.1017/s1357729800014156.

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AbstractThere have been suggestions that positive feedback from the meal may stimulate the performance of undesirable behaviour, such as stereotypies, in the post-feeding period. The aim of this work was to measure the short-term effects of a meal on the post-feeding behaviour of the pig.Pigs (70 kg live weight) were offered food ad libitum for 7 days and then given a restricted food allowance for 23 days (experiment 1) or 14 days (experiment 2). In experiment 1, the food allowance was given in one, two or three meals per day. In experiment 2, the food allowance was given in two meals per day
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M., V. BASAVESWARA RAO, R. SURESH J., KUMAR ARVIND, ILA H., and JUNJAPPA H. "Reaction of Ketene Dithioacetals with Aziridine. A New Synthesis of N-Vinylaziridines and their Iodide Ion-assisted Rearrangement to Pyrrolines." Journal of Indian Chemical Society Vol. 74, Nov-Dec 1997 (1997): 955–60. https://doi.org/10.5281/zenodo.5900960.

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Department of Chemistry, North-Eastern Hill University, Shillong-793 003 Department of Chemistry, Indian Institute of Technology, Kanpur-208 016 <em>Manuscript received 16 October 1997</em> The ketene dithloacetals 1, 4, 9 and 11 react readily with aziridine 2 to give the corresponding <em>N</em>-vinylaziridines 3, 5, 8 and 12 respectively, which on iodide ion-catalyzed rearrangement undergo ring expansion to give pyrrolines 14, 18, 21 and 22 respectively.
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9

Mashayekhi, Mona, Hui Nian, Sara E. Howard, et al. "LBSUN306 Effects Of Glp-1 Receptor Agonism, Dpp4 Inhibition, And Hypocaloric Diet On Metabolic Parameters In Obese Pre-diabetic Individuals: A Randomized-controlled Trial." Journal of the Endocrine Society 6, Supplement_1 (2022): A292—A293. http://dx.doi.org/10.1210/jendso/bvac150.603.

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Abstract Background GLP-1 receptor (GLP1R) agonists reduce glucose, weight and cardiovascular risk. Understanding the weight loss-dependent mechanisms of these benefits will inform treatment and drug development. This study compared metabolic responses among GLP1R agonist (liraglutide), DPP4 inhibitor (sitagliptin), and hypocaloric diet treatments. Methods We randomized 88 obese, pre-diabetic individuals in a 2: 1: 1 ratio to liraglutide, sitagliptin, or diet for 14 weeks. Treatment was double-blinded and placebo-controlled for drug. Individuals completed a mixed meal at baseline, 2 and 14 wee
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Yani, E. V., and V. A. Golikova. "Complex Approach to the Bacterial Corneal Ulcers Treatment." Ophthalmology in Russia 17, no. 4 (2020): 796–803. http://dx.doi.org/10.18008/1816-5095-2020-4-796-803.

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Purpose: Objective: to evaluate the effect of treatment of bacterial corneal ulcers of varying severity using a combination of antibacterial and corticosteroid drugs.Material and methods. 63 patients with bacterial corneal ulcers of varying severity were treated. The study used a quantitative scale to assess the severity of corneal ulcers. Group 1 — patients with mild corneal ulcers (18 patients); Group 2 — patients with moderate corneal ulcer (17 patients); group 3 — severe corneal ulcer (11 patients); control group — patients with mild corneal ulcer (17 patients). Patients of groups 1, 2 and
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ศรีโกไสย, สุนทรี, อุไรวรรณ วงศ์โปธิ, ณัฏฐ์พิมล วงศ์เมือง та อนงค์พร ต๊ะคำ. "การพัฒนาระบบบริการสุขภาพจิตผู้ปกครองของเด็กและวัยรุ่นที่มีปัญหาสุขภาพจิตและพัฒนาการ". Journal of Thailand Nursing and Midwifery Council 38, № 02 (2023): 88–104. http://dx.doi.org/10.60099/jtnmc.v38i02.261791.

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บทนำ ที่ผ่านมายังไม่มีระบบที่ชัดเจนในการบริการสุขภาพจิตผู้ปกครอง และการคัดกรองยังไม่ครอบคลุม มีข้อจำกัดในการเข้าถึงบริการของผู้ปกครองที่มีปัญหาสุขภาพจิต รวมทั้งความเชื่อมโยงระหว่างหน่วยบริการ วัตถุประสงค์การวิจัย เพื่อพัฒนาระบบบริการสุขภาพจิตผู้ปกครองของเด็กและวัยรุ่นที่มีปัญหาสุขภาพจิต และพัฒนาการ ทดสอบประสิทธิภาพและประสิทธิผลของโปรแกรมการบำบัดสังคมจิตใจแบบสั้นแนวซาเทียร์โมเดล การออกแบบวิจัย การวิจัยและพัฒนา วิธีดำเนินการวิจัย การวิจัยแบ่งเป็น 5 ระยะ ทำการศึกษาระหว่าง มกราคม 2563 - ธันวาคม 2565 ระยะที่ 1 วิเคราะห์ ความต้องการความจำเป็น ระยะที่ 2 ออกแบบระบบบริการสุขภาพจิตผู้ปกครอง ระยะที่ 3 สร
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Vio, Carlos P., Mariana Quiroz-Munoz, Catherina A. Cuevas, Carlos Cespedes, and Nicholas R. Ferreri. "Prostaglandin E2 EP3 receptor regulates cyclooxygenase-2 expression in the kidney." American Journal of Physiology-Renal Physiology 303, no. 3 (2012): F449—F457. http://dx.doi.org/10.1152/ajprenal.00634.2011.

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Cyclooxygenase-2 (COX-2) is constitutively expressed and highly regulated in the thick ascending limb (TAL). As COX-2 inhibitors (Coxibs) increase COX-2 expression, we tested the hypothesis that a negative feedback mechanism involving PGE2 EP3 receptors regulates COX-2 expression in the TAL. Sprague-Dawley rats were treated with a Coxib [celecoxib (20 mg·kg−1·day−1) or rofecoxib (10 mg·kg−1·day−1)], with or without sulprostone (20 μg·kg−1·day−1). Sulprostone was given using two protocols, namely, previous to Coxib treatment (prevention effect; Sulp7-Coxib5 group) and 5 days after initiation of
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Department, of Chemistry, Kundu Sajal, Manglembi Devi N., Brajakishor Singh Ch., and Surjit Singh Keisham. "Synthesis, characterization and antibacterial activity of some water soluble ZnII azide complexes with (E)-N-(thiophen-2-ylmethylene)anilines." Journal of Indian Chemical Society Vol. 94, Nov 2017 (2017): 1187–94. https://doi.org/10.5281/zenodo.5633631.

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Department of Chemistry, National Institute of Technology Agartala, Jirania-799 046, Tripura (West), India <em>E-mail</em> : kundu12@gmail.com, surjitkeisham@yahoo.co.in Fax : 91-381-2346360 b Institute of Bio-resources and Sustainable Development, Takyelpat, Imphal-795 001, Manipur, India <em>Manuscript received 27 October 2017, accepted 28 November 2017</em> Four neutral zinc(II) azide complexes of composition [Zn(N<sub>3</sub> )<sub>2</sub> (L<sup>n</sup> )], where L<sup>n</sup> = (<em>E</em>)-N-(thiophen2-ylmethylene)anilines were synthesized. The complexes were characterized by elemental
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14

Loyola Filho, Antônio Ignácio de, Elizabeth Uchoa, Henrique L. Guerra, Josélia O. A. Firmo, and Maria Fernanda Lima-Costa. "Prevalência e fatores associados à automedicação: resultados do projeto Bambuí." Revista de Saúde Pública 36, no. 1 (2002): 55–62. http://dx.doi.org/10.1590/s0034-89102002000100009.

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OBJETIVO: Realizou-se estudo com base populacional na cidade de Bambuí, MG, com cerca de 15.000 habitantes, para determinar a prevalência e os fatores associados ao uso de automedicação. MÉTODOS: Foi selecionada uma amostra aleatória simples de 1.221 moradores com idade &gt;18 anos: 796 relataram uso de medicamentos nos últimos 90 dias e foram incluídos no estudo (775 participaram). A coleta de dados foi feita por entrevistas domiciliares. Foram considerados três grupos de variáveis exploratórias: sociodemográficas, indicadores de condição de saúde e indicadores de uso de serviços de saúde. Pa
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Ay, Cihan, Rainer Vormittag, Daniela Dunkler, et al. "D-Dimer and Prothrombin Fragment 1 + 2 Predict Venous Thromboembolism in Patients With Cancer: Results From the Vienna Cancer and Thrombosis Study." Journal of Clinical Oncology 27, no. 25 (2009): 4124–29. http://dx.doi.org/10.1200/jco.2008.21.7752.

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Purpose Venous thromboembolism (VTE) is a well-recognized complication of cancer. Laboratory parameters might be useful to assess the VTE risk in patients with cancer. The aim of this study was to investigate D-dimer and prothrombin fragment 1 + 2 (F 1 + 2), which reflect activation of blood coagulation and fibrinolysis, for prediction of cancer-associated VTE. Patients and Methods In a prospective, observational, cohort study of 821 patients with newly diagnosed cancer or progression of disease who did not recently receive chemotherapy, radiotherapy, or surgery were enrolled and followed for
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Kampf, A. R., B. P. Nash, M. Dini, and A. A. Molina Donoso. "Magnesiokoritnigite, Mg(AsO3OH)·H2O, from the Torrecillas mine, Iquique Province, Chile: the Mg-analogue of koritnigite." Mineralogical Magazine 77, no. 8 (2013): 3081–92. http://dx.doi.org/10.1180/minmag.2013.077.8.03.

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AbstractThe new mineral magnesiokoritnigite (IMA 2013-049), ideally Mg(AsO3OH)·H2O, was found at the Torrecillas mine, Salar Grande, Iquique Province, Chile, where it occurs as a secondary alteration phase in association with anhydrite, chudobaite, halite, lavendulan, quartz and scorodite. Crystals of magnesiokoritnigite are colourless to pale-pink, thin to thick laths up to 2 mm long. Laths are elongated on [001], flattened on {010} and exhibit the forms {010}, {110}, {10}, {101}, {031} and {01}. The crystals also occur in dense deep-pink intergrowths. Crystals are transparent with a vitreous
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Lebwohl, Mark G., Leon H. Kircik, Angela Y. Moore, et al. "Effect of Roflumilast Cream vs Vehicle Cream on Chronic Plaque Psoriasis." JAMA 328, no. 11 (2022): 1073. http://dx.doi.org/10.1001/jama.2022.15632.

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ImportanceOnce-daily roflumilast cream, 0.3%, a potent phosphodiesterase 4 inhibitor, demonstrated efficacy and was well tolerated in a phase 2b trial of patients with psoriasis.ObjectiveTo evaluate the efficacy of roflumilast cream, 0.3%, applied once daily for 8 weeks in 2 trials of patients with plaque psoriasis.Design, Setting, and ParticipantsTwo phase 3, randomized, double-blind, controlled, multicenter trials (DERMIS-1 [trial 1; n = 439] and DERMIS-2 [trial 2; n = 442]) were conducted at 40 centers (trial 1) and 39 centers (trial 2) in the US and Canada between December 9, 2019, and Nov
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18

Kerst, Corinna, Martin Byloos, and William J. Leigh. "Far-UV laser flash photolysis in solution. A time-resolved spectroscopic study of the chemistry of 1,1-dimethyl-1,3-(1-sila)-butadiene." Canadian Journal of Chemistry 75, no. 7 (1997): 975–82. http://dx.doi.org/10.1139/v97-117.

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Laser flash photolysis (193 nm) of 1,1-dimethyl-(1-sila)cyclobut-2-ene in hexane solution leads to the formation of a transient species [Formula: see text] assigned to 1,1-dimethyl-1,3-(1-sila)butadiene on the basis of its UV absorption spectrum (λmax = 312 nm), and reactivity toward methanol (kMeOH = (3.6 ± 0.1) × 109 M−1 s−1; kH/kD = 1.3 ± 0.1), ethanol (kEtOH = (2.41 ± 0.06) × 109 M−1 s−1), tert-butanol (kBuOH = (1.8 ± 0.1) × 109 M−1 s−1; kH/kD = 1.5 ± 0.1), and oxygen [Formula: see text]. Experiments using isooctane and acetonitrile as solvent are also described. In acetonitrile, the lifet
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Jeong, Sun Young, Myung Jin Chung, Gukmyung Choi, Bong Soo Kim, Seung Hyun Kim, and Ji Kang Park. "A Comparison between Liquid-Crystal Display Monitors and Cathode-Ray Tube Monitors: A Combined Assessment Study of Observer Performances by Using Storage Phosphor and Flat-Panel-Detector Radiography in Detecting Experimentally Induced Pulmonary Edema in." Journal of Medicine and Life Science 6, no. 5 (2009): 351–58. http://dx.doi.org/10.22730/jmls.2009.6.5.351.

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To compare the observer performance 0f liquid crystal display (LCO) and cathode ray tube (CRT) monitors in detecting experimentally induced pulmonary edema in pigs by using soft-copy images of amorphous selenium-based flat-panel-detector radiography (OR) and storage phosphor computed radiography (CR). Oleic acid was injected intra-atrially into three pigs (weight, 20-25kg) at doses of 0.04, 0.05, and 0.06 ml/kg to induce pulmonary edema. Each set of CR, DR, and thin-section CT scans were obtained every 20-30 minutes from three pigs over 4-6hours. Thus, 37 sets (10 sets from pig-1, 11 sets from
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Tebandeke I.Z, Mukasa, Karume I, Ssebuwufu J, Wasajja H.Z, Nankinga R, and Kansiime Z. "How Physicochemical Parameters of Water Change with Distance in a Lake: Case Study Lake Bunyonyiinkigezi." International Journal of Advances in Chemistry 7, no. 4 (2021): 1–22. http://dx.doi.org/10.5121/ijac.2021.7401.

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Pollution resulting from unsustainable agricultural and urbanization activities in the Ruhezamyenda and Bunyonyi catchments are threatening lake Bunyonyi. These have led to high chemical oxygen demand (COD), electrical conductivity, turbidity, pH, iron (II) concentration and low dissolved oxygen (DO5). In this study we have investigated the how COD, turbidity, pH, concentration of iron, total suspended solids, total nutrients and DO5 of water changed with distance in lake. Water sampled from different distances in the lake filtered using Whatman paper at ambient temperatures was tested for COD
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Mårtensson, E. M., E. D. Nilsson, G. Buzorius, and C. Johansson. "Eddy covariance measurements and parameterisation of traffic related particle emissions in an urban environment." Atmospheric Chemistry and Physics 6, no. 3 (2006): 769–85. http://dx.doi.org/10.5194/acp-6-769-2006.

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Abstract. Urban aerosol sources are important due to the health effects of particles and their potential impact on climate. Our aim has been to quantify and parameterise the urban aerosol source number flux F (particles m−2 s−1), in order to help improve how this source is represented in air quality and climate models. We applied an aerosol eddy covariance flux system 118.0 m above the city of Stockholm. This allowed us to measure the aerosol number flux for particles with diameters &gt;11 nm. Upward source fluxes dominated completely over deposition fluxes in the collected dataset. Therefore,
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Pookmanee, Pusit, Prakasit Intaphong, and Sukon Phanichphant. "The Characterization of Bismuth Vanadate Powder Synthesized by a Modified Microwave Method." Advanced Materials Research 1103 (May 2015): 85–90. http://dx.doi.org/10.4028/www.scientific.net/amr.1103.85.

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Bismuth vanadate (BiVO4) powder was synthesized by a modified microwave method. Bismuth nitrate pentahydrate, ammonium metavanadate and 2-propanol were used as the starting precursors. The final pH of solution was adjusted to 7 and irradiation power at 600 Watt for 2 and 6 min. The yellow powder was filtered and dried at 100 °C for 24h. The phase of BiVO4 powder was characterized by X-ray diffractometer (XRD). Multi-phase of monoclinic and tetragonal phase was obtained without calcination step. The morphology of BiVO4 powder was investigated by scanning electron microscope (SEM). The BiVO4 pow
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Aonso-Diego, G., Á. García-Pérez, S. Weidberg, and R. Secades-Villa. "Predictors of smoking cessation treatment attrition in individuals with substance use disorders." European Psychiatry 64, S1 (2021): S823. http://dx.doi.org/10.1192/j.eurpsy.2021.2175.

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IntroductionAttrition rates in smoking cessation treatments are high, particularly in persons with substance use disorders. It is estimated that about 55%% disengage prematurely at treatment, meaning that a large portion will not benefit from smoking abstinence. So far, no previous studies have examined predictors of dropouts in a smoking cessation treatment with persons with SUD.ObjectivesThe study was two-fold: 1) to analyze the percentage of early-, late-dropouts and completers, and 2) to examine sociodemographic, psychological, and substance-related predictors of dropouts.MethodsA total of
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Marincowitz, Carl, Omar Bouamra, Tim Coates, et al. "1427 The effect of the COVID-19 pandemic on major trauma presentations and patient outcomes in English hospitals." Emergency Medicine Journal 39, no. 12 (2022): A960.2—A964. http://dx.doi.org/10.1136/emermed-2022-rcem2.2.

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Aims, Objectives and BackgroundThere is evidence that COVID-19 ‘lockdowns’ may have contributed to increased non-accidental injury, domestic violence and self-harm related to deteriorating mental health. Internationally, there is also evidence that the diversion of health care resources may led to worse outcomes for patients presenting with major trauma. There has been no previous national evaluation of ‘lockdown’ measures impact on the characteristics, treatment pathways and outcomes of trauma patients in EnglandWe aimed to assess the impact of successive lockdowns on the volume, demographics
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Rosen, Lee S., Razelle Kurzrock, Marilyn Mulay, et al. "Safety, Pharmacokinetics, and Efficacy of AMG 706, an Oral Multikinase Inhibitor, in Patients With Advanced Solid Tumors." Journal of Clinical Oncology 25, no. 17 (2007): 2369–76. http://dx.doi.org/10.1200/jco.2006.07.8170.

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Purpose AMG 706 is an investigational, orally bioavailable inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, platelet-derived growth factor receptor, and stem-cell factor receptor. This phase I, dose-finding study evaluated the safety, pharmacokinetics, and pharmacodynamics of AMG 706 in patients with refractory advanced solid tumors. Patients and Methods AMG 706 was administered at escalating doses of 50 to 175 mg once daily or 25 mg bid for the first 21 days of a 28-day cycle. The 125-mg once-daily dose was also administered continuously. The maximum-tolerated dose (MTD)
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Lecarpentier, Y., F. X. Blanc, S. Salmeron, J. C. Pourny, D. Chemla, and C. Coirault. "Myosin cross-bridge kinetics in airway smooth muscle: a comparative study of humans, rats, and rabbits." American Journal of Physiology-Lung Cellular and Molecular Physiology 282, no. 1 (2002): L83—L90. http://dx.doi.org/10.1152/ajplung.2002.282.1.l83.

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To analyze the kinetics and unitary force of cross bridges (CBs) in airway smooth muscle (ASM), we proposed a new formalism of Huxley's equations adapted to nonsarcomeric muscles (Huxley AF. Prog Biophys Biophys Chem7: 255–318, 1957). These equations were applied to ASM from rabbits, rats, and humans ( n = 12/group). We tested the hypothesis that species differences in whole ASM mechanics were related to differences in CB mechanics. We calculated the total CB number per square millimeter at peak isometric tension (Ψ ×109), CB unitary force (Π), and the rate constants for CB attachment ( f 1) a
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Nagler, Arnon, Vanderson Rocha, Myriam Labopin, et al. "Allogeneic Hematopoietic Stem-Cell Transplantation for Acute Myeloid Leukemia in Remission: Comparison of Intravenous Busulfan Plus Cyclophosphamide (Cy) Versus Total-Body Irradiation Plus Cy As Conditioning Regimen—A Report From the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation." Journal of Clinical Oncology 31, no. 28 (2013): 3549–56. http://dx.doi.org/10.1200/jco.2013.48.8114.

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Purpose Cyclophosphamide (Cy) combined with total-body irradiation (TBI) or with busulfan (Bu) are currently the most common myeloablative regimens used in allogeneic stem-cell transplantation (alloSCT) in adults with acute myelogenous leukemia (AML). Intravenous (IV) Bu has more predictable bioavailability and a safer toxicity profile than the oral formulation. Comparative studies of outcomes have been performed between oral Bu/Cy and Cy/TBI, but there have been no comparative trials in the era of IV Bu. Patients and Methods We performed a retrospective registry-based study comparing outcomes
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Nigro, Giovanni, Stuart P. Adler, Stefania Lasorella, et al. "High-Dose Cytomegalovirus (CMV) Hyperimmune Globulin and Maternal CMV DNAemia Independently Predict Infant Outcome in Pregnant Women With a Primary CMV Infection." Clinical Infectious Diseases 71, no. 6 (2019): 1491–98. http://dx.doi.org/10.1093/cid/ciz1030.

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Abstract Background After primary maternal cytomegalovirus (CMV) infection during pregnancy, infants are at risk for disease. Methods Factors predictive of infant outcome were analyzed in a database of 304 pregnant women with primary infection. These women were enrolled between 2010 and 2017 and delivered 281 infants, of whom 108 were CMV infected. Long term follow-up occurred for 173 uninfected and 106 infected infants at age 4 years (range, 1–8 years). One hundred fifty-seven women were treated with an average of 2 doses (range, 1–6 doses) of high-dose hyperimmune globulin (HIG: 200 mg/kg/in
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29

Hall, R. D., and W. Jaynes. "Synergized or Unsynergized Permethrin for House Fly Control in Caged Layer Buildings, 1985." Insecticide and Acaricide Tests 11, no. 1 (1986): 466. http://dx.doi.org/10.1093/iat/11.1.466.

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Abstract This experiment was applied in separate, identical caged layer houses ca. 930 m2 each. Such houses contained ca. 10,000 Single Comb White Leghorn (Heisdorf and Nelson) 1-yr-old laying hens in single-tier raised wire cages suspended over shallow manure pits. The sides were open and the houses were separated by ca. 33 m. General sanitary conditions were poor; however, house flies had been controlled effectively with sprays of permethrin emulsifiable concentrate (EC) the previous year. Materials tested included 1) 0.1% active ingredient (AI) Permectrin permethrin EC in 37.9 liters water,
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30

Toomey, Rosemary, Carol E. Franz, Jeremy A. Elman, Ruth E. McKenzie, William S. Kremen, and Michael J. Lyons. "91 Agent Orange Exposure and Mild Cognitive Impairment in U.S. Vietnam Era Veterans." Journal of the International Neuropsychological Society 29, s1 (2023): 392–93. http://dx.doi.org/10.1017/s135561772300526x.

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Objective:US forces used Agent Orange (AO) during the Vietnam War and continued to store/test it at other locations after the war. AO is a powerful herbicide including dioxin, a highly toxic ingredient classified as a human carcinogen. The National Academies of Sciences, Engineering, and Medicine periodically review the literature on the health effects of AO exposure (AOE) and concluded in 2018 that there is sufficient evidence linking AO with a wide range of adverse health outcomes, including neurologic disorders (e.g., Parkinson’s disease). The VA has a list of medical disorders considered p
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31

ZYLUK, A., and P. PUCHALSKI. "Treatment of Early Complex Regional Pain Syndrome Type 1 by A Combination of Mannitol and Dexamethasone." Journal of Hand Surgery (European Volume) 33, no. 2 (2008): 130–36. http://dx.doi.org/10.1177/1753193408087034.

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A total of 75 patients, 68 women (91%) and seven men (9%), with a mean age of 58 (range 38–82) years with early Complex Regional Pain Syndrome Type 1 (CRPS Type 1), present for less than 4 months, were given in-patient treatment with 10% mannitol 2 × 250 ml per day and 8 mg dexamethasone per day for 1 week. Measurements assessed included the pain, the range of finger movements, grip strength and our own clinical severity scoring system for CRPS Type 1 (CRPS score). The results were assessed at 1 week and, finally, at a mean of 9 (range 8–12) months. At 1-week assessment, all variables decrease
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Yeung, Dannii, Takeshi Nakagawa, and Jinmyoung Cho. "RETIREMENT ADJUSTMENT: COMPARISON AMONG CHINESE, JAPANESE, AND KOREAN RETIREES." Innovation in Aging 3, Supplement_1 (2019): S129. http://dx.doi.org/10.1093/geroni/igz038.471.

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Abstract Moving into retirement is a stressful life event. However, recent research findings suggest that not every retiree experiences maladjustment. This paper investigated longitudinal changes in depressive symptoms during the retirement transition utilizing harmonized data of CHARLS, JSTAR, and KLoSA. Participants were selected for examination if meeting the following criteria: They were working in Wave 1 and had retired in Wave 2 (China=1053; Japan=184; Korea=706). These participants were categorized into two subgroups based on their status in Wave 3, either remained retired or reemployed
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33

Killgore, William, Vincent Capaldi, Michael Grandner, and Gary Kamimori. "786 Trait Extraversion is Associated with Increased Suicidal Ideation During Total Sleep Deprivation and Insomnia." Sleep 44, Supplement_2 (2021): A306—A307. http://dx.doi.org/10.1093/sleep/zsab072.783.

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Abstract Introduction It is known that sleep disturbance is associated with increased suicidal thinking, and completed suicides are most common during the late night/early morning hours, but no studies have examined the role of trait-like individual differences in vulnerability to suicidal ideation during sleep deprivation or insomnia. In two separate studies, we examined whether the trait of extraversion is predictive of changes in suicidal thinking following two nights of sleep deprivation and among individuals meeting criteria for insomnia. Methods Study 1: Twenty-five healthy military pers
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Anupam, Bhim, Baishya Saranga, Gurusamy Sivakumar, Gopalakrishnan Jagannatha, and Natarajan Srinivasan. "Realising blue colour in cobalt substituted silicates: Synthesis, structure and optical studies." Journal of India Chemical Society Vol. 95, Dec 2018 (2018): 1579–86. https://doi.org/10.5281/zenodo.5644818.

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Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore-560 012, India <em>E-mail</em>: snatarajan@iisc.ac.in Summer Research Fellow, National Institute of Technology, Shillong-793 003, Meghalaya, India <em>Manuscript received online 30 December 2018, accepted 31 December 2018</em> In an attempt to develop new blue coloured inorganic oxides, we have undertaken the cobalt substitution in Zn<sub>2</sub>SiO<sub>4</sub> and Ba<sub>2</sub>ZnSi<sub>2</sub>O<sub>7</sub>. In both the compounds, Zn occupies a tetrahedral coordination. Our studies indicate formation of single-p
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35

Gouda, Mohamed A., Blessie E. Nelson, Lars Buschhorn, Adam Wahida, and Vivek Subbiah. "Abstract 1173: Landscape of 4,506 pan-cancer samples harboring BRAFV600E mutations, and NTRK/RET Fusions from 137,401 adult patients with cancer: Clinical implications for tissue agnostic therapies." Cancer Research 83, no. 7_Supplement (2023): 1173. http://dx.doi.org/10.1158/1538-7445.am2023-1173.

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Abstract Background: Biomarker-driven trials have led to multiple FDA tissue-agnostic approvals. We aimed to explore the clinic-genomic landscape of alterations currently actionable by tissue-agnostic targeted therapies. Methods: We mined AACR Project GENIE to extract data about three molecular targets currently on the list of FDA tissue-agnostic approvals (RET fusions, NTRK fusions, and BRAFV600E mutations). Results: Among 137401 patients in GENIE database (153,834 samples), 4506 samples harbored BRAFV600E mutations (3%), 390 had NTRK fusions (0.3%), and 375 had RET fusions (0.2%) (Table 1).
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36

Battaglin, Francesca, Joanne Xiu, Yasmine Baca, et al. "Comprehensive molecular profiling of IDH1/2 mutant biliary cancers (BC)." Journal of Clinical Oncology 38, no. 4_suppl (2020): 479. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.479.

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479 Background: Isocitrate dehydrogenases (IDH) play a key role in energetic metabolism and IDH mutations (mut) promote oncogenesis via epigenetic and genetic changes. Data addressing the molecular contexture of IDH1/2 mut in BC are lacking. We aimed to characterize the molecular profile of IDH1/2 mutant (mIDH) GI cancers with a focus on BC. Methods: 27954 GI cancer samples collected between August 2000 and July 2019 were included: 2057 BC (1159 ICC, 277 extrahepatic CC, 573 gallbladder, 48 unspecified CC), 13807 colorectal, 4183 gastric/esophageal, 3060 other. Samples were analyzed using Next
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37

Fleming, P. S., A. T. DiBiase, G. Sarri, and R. T. Lee. "Pain Experience during Initial Alignment with a Self-Ligating and a Conventional Fixed Orthodontic Appliance System." Angle Orthodontist 79, no. 1 (2009): 46–50. http://dx.doi.org/10.2319/121007-579.1.

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Abstract Objectives: To test the hypotheses that (1) there is no difference in the pain experience during the week following initial placement of two orthodontic appliances (SmartClip™ and Victory™; 3M Unitek, Monrovia, Calif); and (2) there is no difference in the pain experience during removal and insertion of orthodontic archwires with these brackets. Materials and Methods: Sixty-six consecutive patients were treated with a self-ligating bracket system (SmartClip™) or a conventional appliance (Victory™) on the basis of computer-generated random allocation. After appliance placement and enga
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von Pawel, Joachim, Joan H. Schiller, Frances A. Shepherd, et al. "Topotecan Versus Cyclophosphamide, Doxorubicin, and Vincristine for the Treatment of Recurrent Small-Cell Lung Cancer." Journal of Clinical Oncology 17, no. 2 (1999): 658. http://dx.doi.org/10.1200/jco.1999.17.2.658.

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PURPOSE: Topotecan and cyclophosphamide, doxorubicin, and vincristine (CAV) were evaluated in a randomized, multicenter study of patients with small-cell lung cancer (SCLC) who had relapsed at least 60 days after completion of first-line therapy. PATIENTS AND METHODS: Patients received either topotecan (1.5 mg/m2) as a 30-minute infusion daily for 5 days every 21 days (n = 107) or CAV (cyclophosphamide 1,000 mg/m2, doxorubicin 45 mg/m2, and vincristine 2 mg) infused on day 1 every 21 days (n = 104). Eligibility included the following: bidimensionally measurable disease, Eastern Cooperative Onc
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39

Yoo, J., K. J. Leonard, D. F. Lee, et al. "Effects of Conversion Parameters on the Transport Properties of YBCO Films in the BaF2 Ex Situ Process." Journal of Materials Research 19, no. 4 (2004): 1281–89. http://dx.doi.org/10.1557/jmr.2004.0166.

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The effects of conversion parameters on transport properties of YBa2Cu3O7-δ (YBCO) films on rolling assisted biaxially textured substrates (RABiTS) in the BaF2 ex situ process were investigated for total pressures Ptotal between 0.1 and 1.3 atm, water vapor pressures PH2O between approximately 7 and 70 Torr and processing temperatures TS between 700 and 790 °C. For this study, a 0.3-μm-thick Y–BaF2–Cu–O precursor film was deposited on a 1-cm-wide Ni=3 at.% W RABiTS with a buffer layer architecture of CeO2/YSZ/Y2O3/Ni deposited in single passes in various reel-to-reel systems for each layer. Un
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40

Xiang, L., A. Low, Y. Y. Leung, et al. "POS1413 INTERVAL BETWEEN SYMPTOM ONSET AND DIAGNOSIS AMONG PATIENTS WITH AUTOIMMUNE RHEUMATIC DISEASES IN A MULTI-ETHNIC ASIAN POPULATION." Annals of the Rheumatic Diseases 80, Suppl 1 (2021): 990.1–990. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1713.

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Background:The interval between symptom onset and diagnosis can often be longer than is ideal in autoimmune rheumatic diseases (ARDs).Objectives:We aimed to characterise this interval among patients newly diagnosed with ARDs in a multi-ethnic Asian population and to identify factors associated with a longer interval.Methods:We used Scott’s model of pathways to treatment to characterise the interval between symptom onset and diagnosis into 4 intervals: #1 between symptom onset and first seeking medical attention, #2 between first medical attention and rheumatology referral, #3 between rheumatol
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41

Mulyadi, Mulyadi. "Relationship on Education Level and Mother's Attitudes About Exclusive Association With Nutritional Status of Children." Eduvest - Journal of Universal Studies 1, no. 5 (2021): 373–82. http://dx.doi.org/10.36418/edv.v1i5.71.

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The magnitude of the problem of malnutrition in infants is a health problem for citizens in Indonesia. This research aims to analyze the relationship between knowledge and behavior of mothers about breastfeeding and exclusive breastfeeding with the nutritional status of infants aged 6- 24 months. This research used a quantitative observational analytic method with a cross sectional approach. The research population consisted of 98 mothers and toddlers aged 6- 24 months in Kayu Raja Village, Keritang Indragiri Hilir Subdistrict and 78 illustrations, using random sampling method. The questionnai
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42

Mikhaleva, Mariia, Svitlana Tyekucheva, Kiyomi Mashima, Stacey M. Fernandes, Matthew S. Davids, and Jennifer R. Brown. "Higher Mutational Burden Is an Independent Predictor of Shorter Time to First Treatment in Untreated Chronic Lymphocytic Leukemia Patients." Blood 142, Supplement 1 (2023): 3270. http://dx.doi.org/10.1182/blood-2023-173738.

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Background. Recent advancements in next-generation sequencing (NGS) technologies have revolutionized the ability to comprehensively profile chronic lymphocytic leukemia (CLL), unveiling various molecular lesions. Complex mutational landscapes and diverse combinatorial patterns of genetic alterations lead to heterogeneity of clinical course and outcomes. The primary objective of this study was to identify patterns of co-occurrence (CO) and mutual exclusivity (ME) among mutations in CLL and their impact on time to first treatment (TTFT). Methods. The cohort included 795 treatment-naïve (TN) pati
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43

NONGMAITHEM, RAJMUHON SINGH, RAJEN SINGH NONGMAITHE, and MANIHAR SINGH AKOHAM. "Studies on Outer-sphere Association of some Cobalt(III) Mixed Ligand Complexes in Aqueous Solutions." Journal of Indian Chemical Society Vol. 70, Aug 1993 (1993): 665–69. https://doi.org/10.5281/zenodo.6120190.

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Department of Chemistry, Manipur University, Imphal-795 003 <em>Manuscript received 30 Jan</em><em>u</em><em>ary 19</em>9<em>2, revised 1 October&nbsp;1992, accepted 2 February 1993</em> The outer-sphere association of Co<sup>III</sup>&nbsp;mixed ligand complexes of the type [Co(L)(AMUH)<sub>2</sub>]&nbsp;X<sub>3</sub> (L = ethylenediamine, 2,2&#39;-dipyridyl and 1,10-phenanthroline; AMUH&nbsp;= I -amidino-<em>O</em>-alkylurea; X = CI, Br and I) has been studied. Coduc-t<em>ʹ</em>ometric studies of the equilibrium [Co(L)(AMUH)<sub>2</sub>]<sup>3+</sup>&nbsp;+ X<sup>-</sup>\(\rightleftharpoons\
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44

Kengne, Francis Barnabe, Michele Loirette Simo Simo, Therese Merline Mekongo Mbezele, Jean Paul Awono, Carine Fokam Tagne, and Noel Vogue. "Evaluation of Medical Technologies Used to Manage Malaria in Efoulan Health District of Yaounde-Cameroon." European Journal of Medical and Health Research 1, no. 2 (2023): 58–68. http://dx.doi.org/10.59324/ejmhr.2023.1(2).08.

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Purpose: This study aimed at evaluating medical technologies used to manage malaria at Efoulan health’s district. Problem: With almost 3 million of confirmed cases per year, malaria is the disease that most affects Cameroonians. From March 2020, Cameroon witnessed the advent of massive cases of COVID-19, whose symptoms almost coincide with those of malaria, causing a mix of medical technologies meanwhile, populations and medical personnel are required not to get confused between malaria and Covid-19. Methods: We conducted a retrospective cross-sectional qualitative study for analytical purpose
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Kengne, Francis Barnabe, Simo Michele Loirette Simo, Mbezele Therese Merline Mekongo, Jean Paul Awono, Carine Fokam Tagne, and Noel Vogue. "Evaluation of Medical Technologies Used to Manage Malaria in Efoulan Health District of Yaounde-Cameroon." European Journal of Medical and Health Research 1, no. 2 (2023): 58–68. https://doi.org/10.59324/ejmhr.2023.1(2).08.

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Purpose: This study aimed at evaluating medical technologies used to manage malaria at Efoulan health&rsquo;s district. Problem: With almost 3 million of confirmed cases per year, malaria is the disease that most affects Cameroonians. From March 2020, Cameroon witnessed the advent of massive cases of COVID-19, whose symptoms almost coincide with those of malaria, causing a mix of medical technologies meanwhile, populations and medical personnel are required not to get confused between malaria and Covid-19. Methods: We conducted a retrospective cross-sectional qualitative study for analytical p
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46

Karkash, Ahmad, Weston He, Paresh Kumar, Mya Tran, Julian A. Marin-Acevedo, and Misty Dawn Shields. "Comparison of outcomes for patients diagnosed with small cell lung cancer between a university and safety net hospital." Journal of Clinical Oncology 43, no. 16_suppl (2025): 12077. https://doi.org/10.1200/jco.2025.43.16_suppl.12077.

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12077 Background: With immunotherapy, the five year overall survival (OS) for small cell lung cancer (SCLC) is 12%. However, real world factors such as social determinants of health (SDH) and enrollment to clinical trials may vary. Here, we compare treatment patterns and outcomes for SCLC between two affiliated hospital settings. Methods: A retrospective analysis was conducted on patients with SCLC seen at university hospital (UH, Indiana University Melvin and Bren Simon Comprehensive Cancer Center) or its affiliate safety net hospital (SNH, Sidney and Lois Eskenazi Hospital) from 1/1/2018 to
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47

Pirogov, Yuriy I., Galina M. Butina, Roman A. Morozov, et al. "Our experience of bromfenac-containing NSAID use in patients after cataract surgery." Ophthalmology journal 9, no. 2 (2016): 53–56. http://dx.doi.org/10.17816/ov9253-56.

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Postoperative cystoid macular edema is an autoimmune reaction due to the blood-retinal barrier breakdown occurring at anterior segment inflammation. Aim: To analyze the effectiveness of various anti-inflammatory therapeutic schemes used in cataract surgery. Materials and methods. Phacoemulsification using similar consumables had been performed in 792 patients (932 eyes). They were divided into three groups: 1st group included patients receiving 1 to 3 dexamethasone (0.3 ml) and mesatone (0.1 ml) injections and Tobradex eye drops starting with 5 times a day for 4-5 weeks and then tapering (356
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48

Huang, Xinran, Jiang Li, Mingxiao Su, Xiyun Jiao, Qiuming Wu, and Zhe Gu. "Exploration of Microbially Induced Carbonate Precipitation Technology for the Protection of Soil on Agricultural Drainage Ditch Slopes." Water 17, no. 13 (2025): 2010. https://doi.org/10.3390/w17132010.

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Microbially induced carbonate precipitation (MICP) offers an eco-friendly approach to stabilize porous materials. This study evaluates its feasibility for protecting agricultural drainage ditch slopes through laboratory tests. Liquid experiments assessed calcium carbonate (CaCO3) precipitation rates under varying bacteria–cementation solution ratios (BCR), cementation solution concentrations (1–2 mol/L), and urease inhibitor (NBPT) contents (0–0.3%). Soil experiments further analyzed the effects of solidified layer thickness (4 cm vs. 8 cm) and curing cycles on soil stabilization. The results
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49

Rivera Teran, V., M. Pérez Rodríguez, D. Alpizar-Rodriguez, et al. "AB1229 SAFETY OF BIOSIMILAR ETANERCEPT IN THE TREATMENT OF RHEUMATIC DISEASES: DATA FROM THE MEXICAN ADVERSE EVENTS REGISTRY (BIOBADAMEX)." Annals of the Rheumatic Diseases 79, Suppl 1 (2020): 1905.1–1906. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3819.

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Background:Access to biosimilar drugs in Mexico started on 2014. Although biosimilar drugs safety has proved comparability to originator drugs on trials, information about its safety on real-life data is limited.Objectives:To compare safety in terms of adverse events of biosimilar etanercept (BEt) to originator etanercept (OEt) using information from the Mexican Adverse Events Registry (BIOBADAMEX).Methods:BIOBADAMEX is a Mexican cohort that collects the information of biologic and biosimilar drugs used in patients with rheumatic diseases in public and private practice since 2016. Patients enr
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50

Alexeeff, Stacey E., Kamala Deosaransingh, Stephen Van Den Eeden, Joel Schwartz, Noelle S. Liao, and Stephen Sidney. "Association of Long-term Exposure to Particulate Air Pollution With Cardiovascular Events in California." JAMA Network Open 6, no. 2 (2023): e230561. http://dx.doi.org/10.1001/jamanetworkopen.2023.0561.

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ImportanceLong-term exposure to fine particulate air pollution (PM2.5) is a known risk factor for cardiovascular events, but controversy remains as to whether the current National Ambient Air Quality Standard (12 μg/m3 for 1-year mean PM2.5) is sufficiently protective.ObjectiveTo evaluate the associations between long-term fine particulate air pollution and cardiovascular events using electronic health record and geocoded address data.Design, Setting, and ParticipantsThis retrospective cohort study included adults in the Kaiser Permanente Northern California integrated health care system durin
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