Academic literature on the topic '8-oxo-7'

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Journal articles on the topic "8-oxo-7"

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Larson, S. B., H. B. Cottam, and R. K. Robins. "Structure of 7-methyl-8-oxo-7,8-dihydroguanosine monohydrate." Acta Crystallographica Section C Crystal Structure Communications 45, no. 12 (1989): 1979–83. http://dx.doi.org/10.1107/s010827018900301x.

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Zbiral, Erich, Shashikant Phadtare, and Walther Schmid. "Strukturelle Abwandlungen anN-Acetylneuraminsäure, 6. Synthesen von 7-Oxo- und 8-Oxo-N-acetylneuraminsäure-Derivaten." Liebigs Annalen der Chemie 1987, no. 1 (1987): 39–43. http://dx.doi.org/10.1002/jlac.198719870107.

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Elix, JA, UA Jenie, and GA Jenkins. "Three New Depsidones From the Lichen Neofuscelia subincerta." Australian Journal of Chemistry 40, no. 12 (1987): 2031. http://dx.doi.org/10.1071/ch9872031.

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The depsidones , glomelliferonic acid (4)(8-hydroxy-3-methoxy-ll-oxo-l-(2-oxopentyl)-6- pentyl -11H-dibenzo[ b,e ] [1,4]dioxepin-7-carboxylic acid), loxodellonic acid (5) (8-hydroxy-3-methoxy-11-oxo-1-(2-oxopenty1)-6-propyl-llH-dibenzo[ b,e ][l,4]dioxepin-7-carboxylic acid) and glomellonic acid (6) (8-hydroxy-3-methoxy-1l-oxo-l,6-di(2-oxopentyl)-11H- dibenzo [ b,e ][l,4]dioxepin-7-carboxylic acid), have been isolated from the lichen Neofuscelia subincerta ( Essl .) Essl . and characterized.
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Heleyová, Katarína, Dušan Ilavský, Vladimír Bobošík, and Naďa Prónayová. "Gould-Jacobs Reaction of 5- and 6-Amino-2-substituted Benzoxazoles. II. Reaction with 3-Ethoxymethylene-2,4-pentanedione and Ethyl 2-Ethoxymethylene-3-oxobutanoate." Collection of Czechoslovak Chemical Communications 61, no. 3 (1996): 371–80. http://dx.doi.org/10.1135/cccc19960371.

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Nucleophilic reaction of 5-amino- and 6-amino-2-substituted benzoxazoles 1 and 2 with 3-ethoxymethylene-2,4-pentanedione (3) gave compounds 5 and 6. Compounds 1 and 2 reacted with ethyl ethoxymethylene-3-oxobutanoate (4) under formation of compounds 7and 8. The substitution products 7 and 8 underwent thermal cyclization at high temperature (boiling mixture of diphenyl ether and biphenyl) to give angularly and linearly annelated derivatives of 5-acetyl-4-oxo-oxazolo[4,5-f]quinoline 9 and 7-acetyl-8-oxo-oxazolo[5,4-g]quinoline 10 (from 7), and derivatives of 8-acetyl-9-oxo-oxazolo[5,4-f]quinolin
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Gornitsky, M., A. M. Velly, S. Mohit, et al. "Altered Levels of Salivary 8-oxo-7-hydrodeoxyguanosine in Breast Cancer." JDR Clinical & Translational Research 1, no. 2 (2016): 171–77. http://dx.doi.org/10.1177/2380084416642197.

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Oxidative stress has been implicated in the pathogenesis of breast cancer (BC). To determine whether BC is associated with altered salivary redox homeostasis, we performed a case-control study assessing the relationship between BC and 8-oxo-7-hydrodeoxyguanosine (8-oxodG), a marker for oxidative damage to DNA. Enzyme-linked immunosorbent assay for 8-oxodG was used on whole, unstimulated saliva of 134 BC patients and 226 healthy controls. Associations of the redox data were assessed by analysis of variance and logistic regression analysis. Our results revealed that there were 1) significantly l
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Yang, Shu-Ping, Li-Jun Han, Xin-Ran He, and Li-Juan Chen. "8-Acetyl-4-methyl-2-oxo-2H-chromen-7-yl acetate." Acta Crystallographica Section E Structure Reports Online 67, no. 12 (2011): o3382. http://dx.doi.org/10.1107/s1600536811048835.

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Zhao, Hui, and Hai-Bin Gong. "8-Hydroxy-3,4,5-trimethyl-6-oxo-2,3,4,6-tetrahydroisoquinoline-7-carboxylic acid." Acta Crystallographica Section E Structure Reports Online 63, no. 10 (2007): o4097. http://dx.doi.org/10.1107/s1600536807045424.

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Banerjee, A. K., and M. Laya. "An alternative synthesis of 8-Methylene-4,4,8a-trimethyl-7-oxo-octahydronaphthalene." Monatshefte f�r Chemie Chemical Monthly 128, no. 12 (1997): 1255–59. http://dx.doi.org/10.1007/bf00807257.

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Thokchom, Herojit S., Anita D. Nongmeikapam, and Warjeet S. Laitonjam. "Synthesis of fused pyrazolo-, isoxazolo-, pyrimido-, and pyridopyrimidines." Canadian Journal of Chemistry 83, no. 8 (2005): 1056–62. http://dx.doi.org/10.1139/v05-054.

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A systematic study of the synthesis of the 5,7-diaryl-4-oxo-pyrazolo[3,4-d]pyrimidin-6-thiones (3), 2-phenyl-5,7-bis(2′-methylphenyl)-4-oxo-pyrazolo[3,4-d]pyrimidin-6-thiones (4b), 2(3H)-3-phenyl-5,7-diaryl-4-oxo-pyrazolo[3,4-d]pyrimidin-6-thiones (5), 5,7-diaryl-4-oxo-isoxazolo[5,4-d]pyrimidin-6-thiones (7), 3,5,7-triaryl-2,3-dihydro-4-oxo-isoxazalo[5,4-d]pyrimidin-6-thiones (8), 2-amino-6,8-diaryl-5-oxo-pyrimido[4,5-d]pyrimidin-7-thiones (9), 3,4-dihydro-2-amino-4-phenyl-6,8-diaryl-5-oxo-pyrimido[4,5-d]pyrimidin-7-thiones (10), 3-cyano-6,8-diaryl-2,5-dioxo-pyrido[2,3-d]pyrimidin-7-thiones (1
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Shi, Hui, Ren Ishikawa, Choon Han Heh, Shigeki Sasaki, and Yosuke Taniguchi. "Development of MTH1-Binding Nucleotide Analogs Based on 7,8-Dihalogenated 7-Deaza-dG Derivatives." International Journal of Molecular Sciences 22, no. 3 (2021): 1274. http://dx.doi.org/10.3390/ijms22031274.

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MTH1 is an enzyme that hydrolyzes 8-oxo-dGTP, which is an oxidatively damaged nucleobase, into 8-oxo-dGMP in nucleotide pools to prevent its mis-incorporation into genomic DNA. Selective and potent MTH1-binding molecules have potential as biological tools and drug candidates. We recently developed 8-halogenated 7-deaza-dGTP as an 8-oxo-dGTP mimic and found that it was not hydrolyzed, but inhibited enzyme activity. To further increase MTH1 binding, we herein designed and synthesized 7,8-dihalogenated 7-deaza-dG derivatives. We successfully synthesized multiple derivatives, including substituted
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Dissertations / Theses on the topic "8-oxo-7"

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LE, PAGE FLORENCE. "Mutagenese de la 8-oxo-7, 8-dihydroguanine dans les cellules de mammifere." Paris 7, 1998. http://www.theses.fr/1998PA077093.

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Le travail presente porte sur l'etude du mecanisme moleculaire de mutagenese induite par une lesion d'oxydation, la 8-oxo-7,8-dihydroguanine (8-oxog) dans les cellules de mammifere. Nous avons utilise comme systeme d'etude des vecteurs navettes a adn simple ou double brin portant une lesion 8-oxog unique, transfectes dans les cellules de mammifere. Apres replication, l'adn plasmidique est extrait puis amplifie dans des bacteries pour permettre une analyse des mutations produites. L'analyse de la mutagenese induite apres synthese translesionnelle du vecteur simple brin contenant la lesion dans
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Garcia, Camila Carrião Machado. "Quantificação de danos em DNA induzidos por acetaldeído. Potencial biomarcador de poluição ambiental." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-21072010-134123/.

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O acetaldeído é um comprovado agente mutagênico e carcinogênico, pode ser produzido endogenamente pela oxidação do álcool ingerido em bebidas alcoólicas e alimentos ou exogenamente, inalado como poluente, advindo da oxidação de combustíveis fósseis e etanol. O efeito do acetaldeído foi avaliado em modelos celulares e animais com o propósito de avaliarmos o aumento do estresse oxidativo, por lipoperoxidação, fragmentação do DNA, e a formação de adutos DNA, tais como 8-oxo-7,8-dihidro-2-desoxiguanosina, além de, 1,N2-eteno-2-desoxiguanosina e 1,N2-propano-2-desoxiguanosina que foram analisados p
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Ming, Xin. "DNA containing 7-functionalized 7-deazapurines or 8-Oxo-7-thiaguanine: Synthesis of nucleosides, oligonucleotides and base pairing properties = 7-Funktionalisierte 7-Desazapurine oder 8-Oxo-7-Thiaguanine als Bausteine von DNA: Synthese von Nukleosiden, Oligonukleotiden und Basenpaarungs-Eigenschaften /." Osnabrück : [s.n.], 2008. http://opac.nebis.ch/cgi-bin/showAbstract.pl?sys=000254560.

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Ampadu, Boateng Derrick. "Kinetics of Formation and Oxidation of 8-oxo-7,8-dihydroguanine (8oxoG)." Digital Commons @ East Tennessee State University, 2014. https://dc.etsu.edu/etd/2314.

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8-oxo-7,8-dihydroguanine (8oxoG) is one of the most important base lesions formed during oxidative damage of DNA. The aim of the present research was to investigate the effects of DNA concentration, G content, and the nature of oxidizing species on the kinetics of 8oxoG in model DNA solutions by using HPLC. The experimentally obtained yields of 8oxoG were typically in the range of 2-2.5% of total concentration of guanine. The ratios of the rate constant of hole diffusion in DNA to the rate constant of conversion of the hole into 8oxoG (kd/kr) were calculated from the experimental data using th
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Pierre, Francis. "Recherches dans le domaine de la synthèse du méthoxy-5 oxo-9 dihydro-7, 8 pyranno [2,3-g] indole et d'analogues." Mulhouse, 1986. http://www.theses.fr/1986MULH0001.

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Synthèse à partir de l'addition stéréosélective du gaiacol et de bytynedisate de diméthyle suivie de cyclisation en chromones des acides aryloxyfumoriques formes ; nitration des chromones des en 5 puis réduction en aminochromanones et élaboration de l'indole par synthèse de Fischer
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Shan, Xiu. "Investigation of mRNA oxidation in Alzheimer's disease." Connect to this title online, 2005. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=osu1117205039.

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Thesis (Ph. D.)--Ohio State University, 2005.<br>Title from first page of PDF file. Document formatted into pages; contains xvii, 161 p.; also includes graphics (some col.) Includes bibliographical references (p. 144-161). Available online via OhioLINK's ETD Center
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Guo, Junhong. "Part I: Biological Activities and Cellular Metabolism of 4-Hydroxy-7-oxohept-5-enoate and 5-Hydroxy-8-oxo-6-octenoate LactonesPart II: Carboxyalkylpyrrole, Pentylpyrrole and 4-Oxo-heptanedioic Amide Derivatives of Ethanolamine Phospholipids and Proteins." Case Western Reserve University School of Graduate Studies / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=case1467829630.

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Dany, Anne Laure. "Effets des rayonnements ionisant et solaire chez les vegetaux : formation de lesions de bases de l'adn et activite de reparation de l'une d'entre elles, la 8-oxo-7, 8-dihydroguanine chez arabidopsis thaliana." Université Joseph Fourier (Grenoble), 2001. http://www.theses.fr/2001GRE10033.

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Nous avons cherche a comprendre pourquoi les plantes, alors qu'elles presentent un facteur de risque de perte de l'integrite genetique eleve, n'ont pas un taux de mutations particulierement important. Dans ce but, la formation de differentes lesions de l'adn d'arabidopsis thaliana a ete quantifiee. Par chromatographie liquide haute performance (clhp) couplee a un spectrometre de masse en mode tandem, la formation des produits dimeriques de thymine (pdt), principales lesions de l'adn suite a une exposition a un rayonnement uv-b, a ete evaluee. Nous avons ainsi confirme l'existence de deux types
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Le, Bihan Yann-VaÏ. "Etude structurale et fonctionnelle de la reconnaissance et de la métabolisation de lésions puriques et pyrimidiques dans l'ADN par la Formamidopyrimidine-ADN glycosylase." Phd thesis, Université d'Orléans, 2009. http://tel.archives-ouvertes.fr/tel-00488816.

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Les oxydations sur les bases nucléiques constituent l'une des sources principale d'apparition de lésions sur l'ADN, qui peuvent être mutagènes ou létales pour les cellules en l'absence de réparation de l'ADN. La Formamidopyrimidine-ADN glycosylase (Fpg), une enzyme procaryote du système de réparation de l'ADN par excision de base (BER), initie la réparation d'un large panel de lésions de ce type via ses activités ADN glycosylase (excision de la base oxydée) et AP lyase (clivage du site abasique par ß,d-élimination). Nous avons réalisé des études fonctionnelles par des techniques biochimiques e
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Le, Bihan Yann-Vaï. "Étude structurale et fonctionnelle de la reconnaissance et de la métabolisation de lésions puriques et pyrimidiques dans l'ADN par la Formamidopyrimidine-ADN glycosylase." Phd thesis, Université d'Orléans, 2009. http://tel.archives-ouvertes.fr/tel-00504364.

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Les oxydations sur les bases nucléiques constituent l'une des sources principale d'apparition de lésions sur l'ADN, qui peuvent être mutagènes ou létales pour les cellules en l'absence de réparation de l'ADN. La Formamidopyrimidine-ADN glycosylase (Fpg), une enzyme procaryote du système de réparation de l'ADN par excision de base (BER), initie la réparation d'un large panel de lésions de ce type via ses activités ADN glycosylase (excision de la base oxydée) et AP lyase (clivage du site abasique par β,δ-élimination). Nous avons réalisé des études fonctionnelles par des techniques biochimiques e
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Books on the topic "8-oxo-7"

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Isocyclische Monooxo-Verbindungen und Polyoxo-Verbindungen. - Isocyclische Hydroxy-oxo-Verbindungen.: Als Ergänzung des 7. und 8. Bandes des Hauptwerkes. 4th ed. Springer, 2031.

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Book chapters on the topic "8-oxo-7"

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Winkelmann, Jochen. "Diffusion coefficient of 3-(7-hydroxy-8-methyl-4-oxo-4H-1-benzopyran-3-yl)-benzoic acid ethyl ester in methanol." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_921.

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Winkelmann, Jochen. "Diffusion coefficient of 3-(7-hydroxy-8-methyl-4-oxo-4H-1-benzopyran-3-yl)-benzoic acid ethyl ester in acetonitrile." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_922.

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Winkelmann, Jochen. "Diffusion coefficient of 3-(7-hydroxy-8-methyl-4-oxo-4H-1-benzopyran-3-yl)-benzoic acid ethyl ester in ethanol." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_923.

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Winkelmann, Jochen. "Diffusion coefficient of 3-(7-hydroxy-8-methyl-4-oxo-4H-1-benzopyran-3-yl)-benzoic acid ethyl ester in propan-2-ol." In Diffusion in Gases, Liquids and Electrolytes. Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-540-73735-3_924.

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"1α-Angeloyloxy-3α,4β,5α(H)-oplopan-8-en-7,14-dione (1α-Angeloyloxy-7-oxo-isoanhydrooplopanone)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0539-9_1893.

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"1α-Anisoyloxy-3α,4β,5α(H)-oplopan-8-en-7,14-dione (1α-Anisoyloxy-7-oxo-isoanhydrooplopanone)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0539-9_1900.

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"1α-Cinnamoyloxy-3α,4β,5α(H)-oplopan-8-en-7,14-dione (1α-Cinnamoyloxy-7-oxo-isoanhydrooplopanone)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0539-9_1901.

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Taber, Douglass F. "Enantioselective Synthesis of Alcohols and Amines: The Ichikawa Synthesis of (+)-Geranyllinaloisocyanide." In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0034.

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Shuichi Nakamura of the Nagoya Institute of Technology reduced (Angew. Chem. Int. Ed. 2011, 50, 2249) the α-oxo ester 1 to 2 with high ee. Günter Helmchen of the Universität-Heidelberg optimized (J. Am. Chem. Soc. 2011, 133, 2072) the Ir*-catalyzed rearrangement of 3 to the allylic alcohol 4. D. Tyler McQuade of Florida State University effected (J. Am. Chem. Soc. 2011, 133, 2410) the enantioselective allylic substitution of 5 to give the secondary allyl boronate, which was then oxidized to 6. Kazuaki Kudo of the University of Tokyo developed (Org. Lett. 2011, 13, 3498) the tandem oxidation of the aldehyde 7 to the α-alkoxy acid 8. Takashi Ooi of Nagoya University prepared (Synlett 2011, 1265) the secondary amine 10 by the enantioselective addition of an aniline to the nitroalkene 9. Yixin Lu of the National University of Singapore assembled (Org. Lett. 2011, 13, 2638) the α-quaternary amine 13 by the addition of the aldehyde 11 to the azodicarboxylate 10. Chan-Mo Yu of Sungkyunkwan University added (Chem. Commun. 2011, 47, 3811) the enantiomerically pure 2-borylbutadiene 15 to the aldehyde 14 to give 16 in high ee. Because the allene is readily dragged out to the terminal alkyne, this is also a protocol for the enantioselective homopropargylation of an aldehyde. Lin Pu of the University of Virginia devised (Angew. Chem. Int. Ed. 2011, 50, 2368) a protocol for the enantioselective addition of 17 to the aldehyde 18 to give 19. Xiaoming Feng of Sichuan University developed (Angew. Chem. Int. Ed. 2011, 50, 2573) a Mg catalyst for the enantioselective addition of 21 to the α-oxo ester 20. Tomonori Misaka and Takashi Sugimura of the University of Hyogo added (J. Am. Chem. Soc. 2011, 133, 5695) 23 to 24 to give the Z-amide 25 in high ee. Marc L. Snapper and Amir H. Hoveyda of Boston College developed (J. Am. Chem. Soc. 2011, 133, 3332) a Cu catalyst for the enantioselective allylation of the imine 26. Jonathan Clayden of the University of Manchester effected (Org. Lett. 2010, 12, 5442) the enantioselective rearrangement of the amide 29 to the α-quaternary amine 30.
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"3α-(5′-Methyldodeca-2′E,4′E,6′E-trienoyloxy)-9β,12-dihydroxy-10βH-eremophil-7(11)-en-8-one (9β,12-Dihydroxy-8-oxo-isosenspeciosoltrienester)." In Natural Compounds. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-0539-9_1044.

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Conference papers on the topic "8-oxo-7"

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Seela, Frank, Xin Ming, and Peter Leonard. "2'-Deoxyimmunosine: stereoselective synthesis and base pairing of oligonucleotides containing 8-oxo-7-thiaguanine." In XIVth Symposium on Chemistry of Nucleic Acid Components. Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 2008. http://dx.doi.org/10.1135/css200810142.

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