Dissertations / Theses: '8115c'

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Touchais, Emmanuelle. "Étude et développement d'une source de plasma micro-onde pour déposer des revetements par pulvérisation sur des grandes surfaces." Grenoble INPG, 1996. http://www.theses.fr/1996INPG0106.

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Les caracteristiques d'une nouvelle source de plasma pour le depot de revetements par pulverisation sur des grandes surfaces ont ete etudiees. Cette source utilise une onde electromagnetique de frequence 2. 45 ghz pour accelerer les electrons qui ionisent les atomes d'argon par impact electronique. Un champ magnetique permet de confiner les electrons pour d'une part optimiser le couplage avec l'onde en tout lieu ou il est egal a 875 gauss et d'autre part transporter le plasma vers une cible de pulverisation polarisee negativement. Une source produisant une nappe de plasma de section rectangulaire de 75 cm2 a ete realisee. La caracterisation du plasma a ete effectuee en termes de densite electronique par interforemetrie, de temperature electronique par mesure de sonde et de courant d'ions recueillis sur la cible en fonction des parametres puissance micro-onde, pression d'argon, champ magnetique. Les valeurs obtenues ont montre que ce plasma est dense, avec une independance entre les parametres de creation du plasma et ceux de la pulverisation. L'usure des cibles de pulverisation est uniforme et correspond a l'intersection entre les lignes de champ magnetique et la surface de la cible. L'etude des couches de chrome deposees par ce procede a montre que la diminution de la pression permet d'obtenir des couches de densite proche de celle du chrome massique, avec des vitesses de depot elevees, et des contraintes residuelles faibles. Sous pression reduite constante, l'incorporation de carbone dans les couches de chrome par pulverisation reactive a permis d'augmenter la durete de ces couches. La morphologie devient plus dense, avec des contraintes residuelles faibles et une resistivite electrique faible. D'autres revetements (fer, oxyde de chrome, oxyde d'aluminium) ont ete realises pour demontrer la potentialite de ce nouveau dispositif a deposer en tension de polarisation negative continue de la cible des materiaux magnetiques et des oxydes

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Fioravanti, Andrea. "La biomimetica dello scaffold nell'ingegneria tissutale dell'osso." Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amslaurea.unibo.it/8115/.

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Ogni giorno nel mondo vengono eseguite migliaia di procedure chirurgiche per sostituire o riparare tessuti che sono stati danneggiati da malattie o traumi. L'ingegneria tissutale rappresenta una strategia alternativa che mira a rigenerare i tessuti danneggiati combinando cellule e biomateriali altamente porosi che fungano da impalcature (scaffolds). In questa tesi compilativa si presenta un approccio recentemente proposto per la rigenerazione del tessuto osseo. Saranno inizialmente descritte caratteristiche e proprietà dell'osso a livello macro e microscopico e il processo riparativo fisiologico. Si illustreranno quindi i principi dell'ingegneria tissutale, evidenziando i biomateriali utilizzabili, le cellule indicate per la rigenerazione e i rapporti funzionali tra di esse e lo scaffold che deve sostenerne la crescita. Successivamente si descriverà il concetto di ‘biomimetica’ dello scaffold e i metodi impiegati per migliorarne la funzionalità, imitando sia l'aspetto meccanico sia quello biologico della reale matrice ossea; verrà trattato infine un caso di scaffold biomimetico realizzato con nanocompositi, che appare un promettente sostitutivo dell'osso.

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3

Cheah, Boon Chong. "Metabolomic sensing system for personalised medicine using an integrated CMOS sensor array technology." Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8115/.

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Precision healthcare, also known as personalised medicine, is based on our understanding of the fundamental building blocks of biological systems, with the ultimate aim to clinically identify the best therapeutic strategy for each individual. Genomics and sequencing technologies have brought this to the foreground by enabling an individual’s entire genome to be mapped for less than a thousand dollar in just one day. Recently, metabolomics, the quantitative measurement of small molecules, has emerged as a field to understand an individual’s molecular profile in terms of both genetics and environmental factors. This is crucial because a genome could only indicate an individual’s susceptibility to a particular disease, whereas a metabolome provides an immediate measurement of body function, enabling a means of diagnosis. However, the current approach of measurements depends on large-scale and expensive equipment such as mass spectroscopy and NMR instrumentation, which does not offer a single analytical platform to detect the entire metabolome. This thesis describes the development of an integrated CMOS sensor array technology as a single platform to quantify different metabolites using specific enzymes. The key stages in the work were: to construct instrumentation systems to perform enzyme assays on the CMOS sensor array; to establish techniques to package the CMOS sensor array for an aqueous environment; to implement and develop a room temperature Ta2O5 sputtering process on CMOS sensor array for hydrogen ion detection; to collaborate with a chemist and investigate an inorganic layer on top of the CMOS ISFET sensor to show an improvement of sensitivity towards potassium ion; to test several different enzyme assays electrochemically and optically and show the functionalities of the sensors; to devise microfluidic channels for segregation of the sensor array into different compartments and perform enzyme immobilisation techniques on CMOS chips; and integrate the packaged chip with microfluidic channels and enzyme immobilisation using 2D inkjet printer into a complete system that has the potential to be used as a multi-enzyme platform for detection of different metabolites. Two CMOS sensor array chips (1) a 256×256-pixel ISFET array chip and (2) a 16×16-pixel Multi-Corder chip were fully understood. Therefore, a high-speed instrumentation system was constructed for the ISFET array chip with a maximum readout speed of 500 frames per second, with 2D and 3D imaging capability, as well as single pixel analysis. Follow by that, a miniaturised measurement platform was implemented for the Multi-Corder chip that has three different sensor arrays, which are ISFET, PD and SPAD. All the sensor arrays can be operated independently or together (ionic sensor and one of the optical sensors). Several post-processing steps were investigated to allow suitable fabrication process on small 4×4 mm2 CMOS chips. Post-processing of the CMOS chips was first established using room temperature sputtering process for Ta2O5 layer, achieving Ta:O ratio of 1:1.77 and a surface roughness of 0.42 nm. This Ta2O5 layer was then fabricated on top of CMOS ISFETs, which improves the ISFET pH sensitivity to 45 mV/pH, with an average drift of 6.5 ± 8.6 mV/hour from chip to chip and a working pH range of 2 to 12. Furthermore, a layer of POMs was drop casted on top of Ta2O5 ISFET to make ISFET sensitive to potassium ions. This was investigated in terms of potassium ions sensitivity, hydrogen ions sensitivity and sodium ions as interfering background ions. The POMs Ta2O5 ISFET was found to have a net potassium sensitivity of 75 mV/pK, with a linear range between pH 1.5 to 3. Moreover, the POMs ISFET has -5 mV/pH in pH sensitivity, showing that it is selectivity towards potassium ions and not hydrogen ions. However, sodium ions were found to produce a large interference towards the pK sensitivity of POMs ISFET and reduced the pK sensitivity of POMs ISFET. Hence, further work is still required to modify POMs layer for better selectivity and sensitivity. Besides that, microfluidic channels were fabricated on top of the CMOS chips that could provide segregation for multiple enzyme assays on a single chip. In addition, a PDMS and a manual dam and fill method were developed to encapsulate the CMOS chips for wet biochemistry measurements. The CMOS sensor array was found to have the ensemble averaging capability to reduce noise as a function of √N , where N is the number of sensors used for averaging. Several enzyme assays that include: hexokinase, lactate dehydrogenase, urease and lipase were tested on the ISFET sensor array. Moreover, using an optical sensor array, namely a PD on the Multi-Corder chip and using LED illumination, quantification of cholesterol levels in human blood serum was demonstrated. Enzyme kinetics calculations were performed for hexokinase and cholesterol oxidase assays and the results were comparable to that obtained from a bench top spectrophotometer. This shows the CMOS sensor array can be used as a low cost portable diagnostic device. Several enzyme immobilisation techniques were explored but were unsuccessful. Alginate enzyme gel immobilisation with a 2D inkjet printer was found to be the best candidate to bio-functionalise the CMOS sensor array. The packaged chip was integrated with microfluidic channels and alginate enzyme gel immobilisation into a complete system, in order to perform an enzyme assay with its control experiments simultaneously on a single chip. As a proof-of-concept, this complete system has the potential to be used as a multiple metabolite quantification platform.

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Viner, Bradley. "Introducing clinical audit into veterinary practice." Thesis, Middlesex University, 2006. http://eprints.mdx.ac.uk/8115/.

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This project has been designed to increase our understanding of the clinical audit process, as it applies to veterinary practice in the UK, and to facilitate its introduction in a manner that brings maximum benefit to all stakeholders. It examines the medical scenario to define the process and glean any relevant information. It then takes the form of an action research project that examines in depth the introduction of the audit process into a small animal practice in outer NW London, including its impact upon the standard of clinical care supplied to its patients, and the sociological effect upon the working environment. The provisional conclusions reached in this way have then been triangulated with the findings of a focus group of veterinarians that are actively involved in the subject, and a broader questionnaire of veterinary practitioners and support staff. The research was able to highlight the key obstacles to introducing clinical audit into a veterinary practice, the benefits that can be achieved when its introduction has been successfully achieved, and how those benefits may ameliorate the time and expense involved. In particular, clinical audit was found to be an effective tool for improving client concordance with the recommended treatment regime for the animals in their care, and thus able to improve both patient welfare and practice income. The sociological changes that are needed to put clinical audit into place successfully, encouraging the development of an integrated team of highly motivated reflective practitioners working within a no-blame practice culture, can bring many additional benefits. This work has taken place at a time when various pressures, such as the RCVS Practice Standards Scheme, and an increased public demand for professional accountability have focused interest in the subject. The author has been leading the way in increasing public awareness of the process, encouraging further research, and ensuring that clinical audit is incorporated into the new modular postgraduate CertAVP designed to develop the learning and skills of the practicing vets of the future.

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Houben, Martinus Henricus Maria Gerardus. "Clinical aspects in Helicobacter pylori infections." [S.l. : Amsterdam : s.n.] ; Universiteit van Amsterdam [Host], 2000. http://dare.uva.nl/document/81155.

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Kim, Jung Hwa M. C. P. Massachusetts Institute of Technology. "International diffusion practice : lessons from South Korea's New Village Movement." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/81150.

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Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 2013.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 104-111).
This research focuses on how South Korea's development model-namely, the Saemaul Undong, or the New Village Movement-is diffused internationally, in particular, to the developing country of Vietnam. South Korea's successful model has been diffused through various different channels for years, mostly in the form of foreign aid projects. Due to the prevailing view that international diffusion practices take place homogenously (in a near-universally standardized manner) within the recipient communities, and due to the propensity on the part of both donor and recipient governments to highlight only successful cases of diffusion while not publicizing those that have failed, several key questions, such as, how diffusion actually takes place, or how each project is likely to bring about different outcomes based on who initiates or leads the project, and to what extent this particular South Korean model has been viable and sustainable in the recipient country, remain largely unveiled. This research, therefore, aims to analyze the role of each stakeholder and how these stakeholders-either personnel or institutions-make an impact on the degree of diffusion of the Saemaul Undong process. It seeks to differentiate the impact of diffusion between short-term or one-time aid projects and those that have managed to become a sustainable development model in the recipient community. To be specific, the roles of politicians, administrative officials at the local level, non-governmental agents, external factors, and minor actors are investigated at the micro-level.
by Jung Hwa Kim.
M.C.P.

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Yeung, Louise H. (Louise Ho-Yee). "Challenges in implementing green workforce development training." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/81154.

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Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 2013.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 44-47).
To meet the labor demands of green economic development, workforce development programs are increasingly training low-income workers for living wage jobs that contribute to environmental services or benefits. Yet, effectively preparing workers for jobs in emergent green economies, which can span many different sectors from energy efficiency to waste management, presents significant challenges for job training programs in practice. This thesis investigates the difficulties of adding a green dimension to job training while still meeting the basic employment objectives of workforce development programs. Through the experiences of the Oakland Green Jobs Corps and the Baltimore Center for Green Careers (BCGC), I analyze the mechanisms through which each program has influenced labor supply and demand to enable jobs in the green economy. Ultimately, the two cases highlight the tradeoffs between achieving green objectives and securing employment for disadvantaged workers at scale. In shedding light on how and why different programmatic decisions have influenced performance outcomes, this thesis aims to inform other cities' decisions in developing green jobs training initiatives.
by Louise H. Yeung.
M.C.P.

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Salazar, Nicole A. (Nicole Antonia). "The Micro-implications of a disintegrating social contract : public pension funds and community investing in New York City." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/81152.

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Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 2013.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 91-97).
Public pension funds are increasingly investing in cities. On the one hand, this appears as a positive development, as an organization traditionally based on exclusionary membership shares its benefits with the larger society. On the other hand, that this is occurring in the context of a disintegrating social contract could be a troubling feature, where private citizens are subsidizing their communities in the absence of state support. The Merriam-Webster dictionary defines "social contract" as "an actual or hypothetical agreement among the members of an organized society.. .that defines and limits the rights and duties of each." The past thirty years in U.S. history have seen a drastic deterioration in the tacit social contract binding the State, Capital and Labor. Transformations affecting these three actors have re-shaped their interactions and bargaining power. Through a discussion of the Varieties of Capitalism and Institutional Change literatures, the first objective of this paper is to make the case that community investing by pension funds is an institution (broadly defined) that has emerged in part because of the historic-economic forces driving the disintegration of the social contract: financialization, neoliberalism, and the decline of the labor movement. The second objective of this paper is to address the following research questions at the city level: What is the relationship between community investing by pension funds and the changing roles of Capital, Labor, and the State? How, in turn, does the design and organization of these institutions impact their ability to influence this relationship? This research finds that pension fund capitalism in New York City may both blunt and obscure the impacts of the weakened social contract. The pension funds could possibly strengthen the position of labor and increase benefits to communities if they incorporated opportunities for learning and capacity building into their programs.
by Nicole A. Salazar.
M.C.P.

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Siddiqi, Faizan Jawed. "Governing urban land : the political economy of the ULCRA in Mumbai." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/81153.

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Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 2013.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 104-112).
In this thesis, I look at the political economy of the Urban Land (Ceiling and Regulation) Act (ULCRA) in Mumbai, India. Enacted in 1976, the stated aim of this legislation was to prevent speculation in the urban land market, and to make land available for affordable housing. The legislation imposed a "ceiling" on the amount of vacant land individuals could hold in urban areas. During the years it was in effect (1976-2007), almost all excess vacant land in the Mumbai agglomeration was exempted under the Act. Current literature posits that ULCRA failed to achieve its objective because politicians and bureaucrats were self-motivated rent-seekers, who were not interested in socially just redistribution of urban land. In 2007, using a conditional intergovernmental transfer scheme, the Central Government forced the State Government of Maharashtra to repeal ULCRA. I argue that current literature offers at best broad generalizations of the reasons ULCRA failed to achieve its objective in Mumbai. Through an in-depth analysis of the working of ULCRA in Mumbai, I show that it was never implemented as originally intended. Also, I show that ULCRA was frustrated by a number of deficiencies in institutions such as the lack of political will to take proactive action, capacity and cohesiveness in the bureaucracy, and amendments in other enabling statutes, to name a few. Seen from this perspective, it is incorrect to assume, as the current national urban development policy does, that a turn to market-led development in urban land markets will yield better results in delivering affording housing for the urban poor. Further, by analyzing the political economy of ULCRA's repeal, I show that under certain conditions, Central Government intervention may be a necessary step to protect interests of the poor. However, Central Government intervention needs to be designed keeping in mind the "why" and the "how", to ensure that the intervention's does not become dead letter, or redundant. I conclude with the dilemmas development planners are likely to face when designing laws and regulations in developing countries that feature a thinly institutionalized state, and a weak democracy.
by Faizan Jawed Siddiqi.
M.C.P.

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Muessig, Anna Catherine. "The re-industrial city : what case studies from New York and San Francisco tell us about the urban manufacturing resurgence." Thesis, Massachusetts Institute of Technology, 2013. http://hdl.handle.net/1721.1/81151.

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Thesis (M.C.P.)--Massachusetts Institute of Technology, Dept. of Urban Studies and Planning, 2013.
"June 2013." Cataloged from PDF version of thesis.
Includes bibliographical references (p. 140-147).
After a century of economic and planning trends that sent industry overseas and to the suburbs, manufacturing is stabilizing, if not growing, in American cities. This is good news for many urbanists eager to attract the economic benefits of industry. However, while economic arguments for urban manufacturing are mature, the spatial strategies for supporting it are scattered or nonexistent. Planning codes and urban design ideals remain set in a 20th century mindset, while today's manufacturing has changed dramatically, becoming smaller and more networked than its previous iteration. Outdated perceptions of manufacturing block progressive policy reform at the highest level. Two thriving manufacturing centers, the Greenpoint Manufacturing and Design Center in New York and the American Industrial Center in San Francisco, provide clues for how 21st century manufacturing is spatializing in cities. These facilities are cultural beacons in their mixed-use neighborhoods and help create a framework for thinking about why urban manufacturing matters in our re-industrializing metropolises. This thesis describes each facility in detail, drawing conclusions about their key characteristics at four spatial scales. Few urban design ideals adequately describe the industrial activity occurring in cities today. Therefore, this thesis builds a system of meaning that values history, economics, and the lived experience of cities as a way to approach urban manufacturing. The emerging lens of Creative Placemaking is invoked as a way to unify these theories, suggesting that urban manufacturing is a superlative form of Creative Placemaking. In conclusion, this thesis provides recommendations and tools for cities looking to cultivate industrial urbanism by offering lessons, developing a framework for a new type of land use classification, and outlining a research brief. The thesis ends with a call for action: as industry continues to change its character, becoming leaner and more technologically driven, cities have great competitive advantage. Planners have a critical opportunity to bring manufacturing back into cities through sensitive, mixed-use zoning that connects people to the process of making and awakens policy professionals to manufacturing as a vital element of the contemporary creative city.
by Anna Catherine Muessig.
M.C.P.

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Castro, Samuel. "Controlo interno dos órgãos de gestão financeira da GNR." Master's thesis, Academia Militar. Direção de Ensino, 2010. http://hdl.handle.net/10400.26/8115.

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O presente trabalho de investigação aplicada visa o tema: “Controlo Interno dos Órgãos de Gestão Financeira da GNR”, o qual reveste uma enorme importância no seio da Guarda. Com a nova estruturação da Guarda a estrutura financeira sofreu mudanças organizacionais, com a extinção e criação de órgãos financeiros. Foi criado o Comando de Administração dos Recursos Internos, que comporta a Direcção de Recursos Financeiros, que por sua vez inclui a Divisão de Controlo e de Auditoria Interna, com a responsabilidade de assegurar a uniformização da administração financeira da Guarda e a realização de auditorias juntamente com a Inspecção da Guarda. Ao nível das Unidades e Serviços foram criadas duas modalidades de órgãos financeiros: as Secções de Recursos Financeiros e as Secções de Recursos Logí sticos e Financeiros. Surge deste modo a necessidade de identificar como o controlo interno está a ser exercido averiguando a existência de diplomas legais sobre o funcionamento destes órgãos financeiros e um manual de controlo interno que preconize todas as normas e procedimentos. Após a pesquisa e tratamento dos dados dos inquéritos e das entrevistas, constata-se que a reorganização da estrutura financeira, iniciando-se ao nível superior e posteriormente ao nível das Unidades e Comandos Territoriais, dinamizou os recursos assim como a comunicação e o apoio entre eles, porém é necessário realizar alguns ajustamentos ao nível da estrutura e dos recursos humanos e a criação de um manual de controlo interno. Além da reestruturação ocorrida na GNR, houve a implementação do Sic Plus com o objectivo de promover o controlo da execução orçamental, aumentar o nível de informação financeira e a uniformidade e verificação da realização de todos os procedimentos legais. Constituindo-se como uma ferramenta de apoio ao controlo interno para os órgãos de inspecção, as acções desenvolvidas nos procedimentos aquisitivos e na arrecadação da receita tornaram-se mais objectivas e menos burocráticas. Sendo um dos objectivos da Guarda tornar o seu controlo interno o mais eficaz e eficiente possível, é necessário adaptar-se aos novos desafios e gerir os riscos inerentes da sua actividade.
Abstract The aim of this research is to study the "Controlo Interno dos Órgãos de Gestão Financeira da GNR". This is a very important subject within the Police organizational structure, also considering that the Finance Office has recently undergone significant structural changes with the merging and creation of new departments. As a result of these changes, a central regulating department has been created, “Comando de Administração dos Recursos Internos”. This Comando is formed by the Finance department, “Direcção de Recursos Financeiros”, and a special division responsible for standardising financial procedures and internal audits, “Divisão de Controlo e de Auditoria Interna”. Within services, two new departments have been created: “Secções de Recursos Financeiros” and “Secções de Recursos Logí sticos e Financeiros”. However, there is still the need to evaluate the effectiveness of their internal procedures and to produce standardised procedures manuals. Hence, several people involved in the new structure have been interviewed. The main conclusion from these interviews is that this new structure is more dynamic and the flow of information is significantly improved between various “Unidades e Comandos Territoriais”. Nevertheless, the need for small adjustments to the overall structure, to the human resources and the need for a manual which compiles standardised internal procedures have been identified. Moreover, a “Sic Plus” has been implemented to improve the level of financial information and budget control, and to check that any relevant legal requirement has been followed. This is a complementary tool to support the inspection department: for instance, the procedures to buy and store items are more objective and less bureaucratic. It is extremely important that GNR improves its internal control. So that GNR can swiftly adapt to the new challenges in society and to manage efficiently the risk embedded in their professional activity.

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川上, 尚恵. "日本占領下の北京における日本語教育 : 体験者へのインタビュー." 名古屋大学言語文化研究会, 2005. http://hdl.handle.net/2237/8115.

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Sabaté, Carrové Mariona. "Towards a theory of translation pedagogy based on computer-assisted translation tools for Catalan and English non literary texts." Doctoral thesis, Universitat de Lleida, 2000. http://hdl.handle.net/10803/8115.

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This dissertation aims to propose an approach to translation pedagogy along two main guidelines: a) evaluating the traditional approaches to translation pedagogy with a view to designing a more ecclectic approach b) implementing computer-assisted tools to translation pedagogy based on classroom and other experimental activities.

The ecclectic approach proposed in this dissertation highlights the importance of including computers in teaching translation and other computer-assisted tools (machine translation, translation memories such as Trados') to improve the students' performance and preparation for professional translation.

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Röhn, Oliver. "Three empirical essays on the determinants of economic growth." kostenfrei, 2008. http://edoc.ub.uni-muenchen.de/8115/.

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Collie, Angela M. B. "The macrophage response to biomaterial topography : gene expression, integrin signaling, and surface adhesions /." Thesis, Connect to this title online; UW restricted, 2006. http://hdl.handle.net/1773/8115.

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Silva, Manuel Duarte de Vasconcelos. "Runaway stars in the Galactic halo : their origin and kinematics." Thesis, University of Hertfordshire, 2012. http://hdl.handle.net/2299/8115.

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Star formation in the Milky Way is confined to star-forming regions (OB association, HII regions, and open clusters) in the Galactic plane. It is usually assumed that these regions are found preferably along spiral arms, as is observed in other spiral galaxies. However, young early-type stars are often found at high Galactic latitudes, far away from their birthplaces in the Galactic disc. These stars are called runaway stars, and it is believed that they were ejected from their birth- places early in their lifetimes by one of two mechanisms: ejection from a binary system following the destruction of the massive companion in a supernova type II event (the binary ejection mechanism), or ejection from a dense cluster following a close gravitational encounter between two close binaries (the dynamical ejection mechanism). The aims of our study were: to improve the current understanding of the nature of high Galactic latitude runaway stars, in particular by investigating whether the theoretical ejection mechanisms could explain the more extreme cases; to show the feasibility of using high Galactic latitude stars as tracers of the spiral arms. The main technique used in this investigation was the tracing of stellar orbits back in time, given their present positions and velocities in 3D space. This technique allowed the determination of the ejection velocities, flight times and birthplaces of a sample of runaway stars. In order to obtain reasonable velocity estimates several recent catalogues of proper motion data were used. We found that the evolutionary ages of the vast majority of runaway stars is consistent with the disc ejection scenario. However, we identified three outliers which would need flight times much larger then their estimated ages in order to reach their present positions in the sky. Moreover, the ejection velocity distribution appears to be bimodal, showing evidence for two populations of runaway stars: a “low” velocity population (89 per cent of the sample), with a maximum ejection velocity of about 300 kms−1, and a “high” velocity population, with ejection velo- cities of 400 – 500 kms−1. We argue that the observed bimodality and maximum ejection velocity of 500 kms−1 can be interpreted as a natural consequence of a variation of the binary ejection mechanism. A possible connection between the “high” velocity population and the so-called hypervelocity stars is also explored, resulting in the conclusion that some stars previously identified as hypervelocity may be in fact runaway stars. The feasibility of using stars as tracers of the spiral arms was tested on a local sample, in order to obtain better quality data and larger numbers. We found that the spiral arms pattern speeds estimated from this sample (24.9±5.2 kms−1 kpc−1) and from a selected sample of runaways (22.8 ± 7.8 kms−1 kpc−1) are consistent within the errors and also consistent with other published estimates. We concluded that our estimates combined with the ones obtained in other studies suggest a value in the range 20 − 25 kms−1 kpc−1 for the pattern speed. Moreover, we concluded that an adequate representation of the spiral arms is obtained given the former pattern speed estimate, even when applied to the sample of runaway stars.

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Arshad, Darwina A. "Understanding organisational improvisation : foundations and performance implications." Thesis, Loughborough University, 2011. https://dspace.lboro.ac.uk/2134/8115.

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This research is grounded in strategy process theory and contingency theory and the main research aims are to investigate the antecedent factors affecting organisational improvisation and to identify how improvisation determines firm performance. This study is the first to examine the antecedent factors, which are categorised onto managerial and organisational factors that drive improvisation. The managerial factors contain the reasoning ability of managers (intuitive and rational) and managers' characteristics (selfconfidence, manager's expertise and attitude towards risk‐taking). Whilst the organisational factors include organisational structure and characteristics (goal clarity, organisational structure, organisational flexibility and organisational risk‐taking), and information processing (organisational information and organisational memory). Environmental turbulence (technology, market and competitive) is examined as an external moderating factor to the improvisation–performance relationship. Fifteen hypotheses were developed and examined in this study. A cross sectional survey methodology was used to test the hypotheses of this study. A postal questionnaire primary data was collected from 128 top management executives of high technology‐based companies in Malaysia. In summary, the findings confirm that a total accumulated variance in organisational improvisation was collectively explained by managerial factors and organisational factors; thus confirming that those aforementioned factors have statistically significant associations with organisational improvisation. Based on the study of the improvisation–performance relationship, the results revealed a positive significant relationship between both factors. Surprisingly, once the environmental turbulence factors were introduced as a moderator, the result on the association between improvisation and firm performance was greater than before; thus demonstrating a significant moderating effect on the relationships between organisational improvisation and firm performance. However, mixed results were identified when the association between each antecedent and improvisation was tested and the effect of each moderating factor was individually examined. This study on the effect of internal and external factors on organisational improvisation and firm performance makes novel contributions to the existing body of knowledge as well as to practitioners. It is noticeable that organisational improvisation in strategic management is crucial as a decision‐making mechanism for improving organisational performance. Hence, managers themselves as well as other relevant factors within firm hierarchy should facilitate and induce necessary condition that may drive organisational improvisation to happen.

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Quach, Andrew Sieunguyen. "Gender differences in parenting, adolescent functioning, and the relation between parenting and adolescent functioning In urban mainland Chinese families." College Park, Md.: University of Maryland, 2008. http://hdl.handle.net/1903/8115.

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Thesis (Ph. D.) -- University of Maryland, College Park, 2008.
Thesis research directed by: Dept. of Family Studies. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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Pereira, Fernanda dos Santos. "Detecção de mutações em pacientes brasileiros com Doença de Fabry." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2005. http://hdl.handle.net/10183/8115.

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A Doença de Fabry (DF) é uma desordem lisossomal ligada ao X causada pela deficiência da enzima alfa-galactosidase A, que provoca acúmulo de globotriaosilceramida (Gb3). O gene que codifica essa enzima está localizado no braço longo do cromossomo X, na região Xq21.33-Xq22, chama-se gene GLA e é composto por 12Kb divididos em sete exons. As manifestações clínicas incluem hipohidrose, angioqueratomas, acroparestesias e opacidade corneana. A progressão da doença leva a doenças vasculares secundárias envolvendo rins, coração e sistema nervoso central. A detecção de mulheres portadoras baseada somente na análise enzimática muitas vezes é inconclusiva. Portanto, a análise de mutações é uma ferramenta fundamental para diagnóstico e aconselhamento genético. A heterogeneidade da DF é alta e a maioria das mutações são privadas. Neste estudo nós descrevemos a análise molecular de seis pacientes homens pertencentes a quatro famílias diferentes e suas mães. O seqüenciamento automatizado dos sete exons do gene GLA revelou a presença de três mutações não conhecidas e uma descrita anteriormente em outra família brasileira. Aparentemente, ambas as famílias não são relacionadas, mas estudos futuros utilizando análise de haplótipos esclarecerão esta situação. Uma mãe era portadora, a outra não. Este estudo confirma a heterogeneidade de mutações que causam DF. Isto também destaca a importância da análise molecular para detecção de portadoras e aconselhamento genético.
Fabry disease is a an X-linked lysosomal disorder due to the deficiency of α- galactosidase A that causes storage of globotriaosylceramide (Gb3). The gene coding for this lysosomal enzyme is located at the long arm of X chromosome, on region Xq21.33 – Xq22, called GLA gene and spans 12kb and is divided in seven exons. Clinical manifestations include hypohidrosis, angiokeratomas, acroparesthesias and corneal opacities. Disease progression leads to vascular disease secondary to involvement of kidney, heart and the central nervous system. Detection of female carriers based solely on enzyme assays is often inconclusive. Therefore, mutation analysis is a valuable tool for diagnosis and genetic counseling. However there is high genetic heterogeneity and most mutations are private. In this study we describe the molecular analysis of six male Fabry patients belonging to four different families and their mothers. Automated sequencing of the seven exons of GLA gene revealed the presence of three unknown mutations and one previously described in another Brazilian family. Apparently, both families are not related but further studies using haplotype analysis shall clarify this question. All but one of the studied mothers were carriers. This study confirms the heterogeneity of mutations in Fabry disease. It also highlights the importance of molecular analysis for carrier detection and genetic counseling.

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Silva, Raquel Belisario da. "Entre o muro concreto e a cortina invisível." Pontifícia Universidade Católica do Rio Grande do Sul, 2016. http://hdl.handle.net/10923/8115.

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This research explores, in Eastern European countries contemporary literature, some possibilities of trauma fictionalization when you live in an area restrained by an authoritarian state. During the Cold War, the inhabitants of countries aligned with the Socialist Soviet regime suffered with general restrictions such as the limitation of freedom of movement, the government control of the economy and the food shortages, but also suffered with a constant threat: the possibility of a nuclear war happened. Furthermore, citizens who were denounced as enemies of the state passed to be persecuted by the political police, which manipulated them through surveillance, physical violence and emotional instability. The repression atmosphere, the fear and the violence were components of a disturbing reality that created conditions for a cumulative trauma existence. The aim of this paper is to check how the traumatic experience of this time and the trauma resistance strategies are represented in literature written after the end of communist dictatorship. For this purpose, three works were selected: Am kürzeren Ende der Sonnenallee, by Thomas Brussig; A fehér király, by György Dragoman; and Heute wär ich mir lieber nicht begegnet, by Herta Müller.The works were analyzed in the light of theorists such as Theodor W. Adorno, Michel de Certeau, Gaston Bachelard, Linda Hutcheon, Boris Uspenski, among others. As in these three novels the historical context interferes in different ways in the characters’ lives, the books were analyzed separately to make possible to identify, in each one, the periods of trauma construction and internalization. This division remains in the final chapter, where the compositional aspect of the works is checked, taking into account the narrator and his spatiotemporal point of view, the organization of narrated memory and the distorting mirrors through which the period is revisited. From these analyzes, it was observed that, although they have some differences, the narratives studied bring some features that approach then and that can be considered specific representations of literature that focuses on the Cold War period.
Esta pesquisa pretende explorar, na literatura contemporânea dos países do Leste Europeu, algumas possibilidades de ficcionalização do trauma de viver em um espaço dominado por um Estado autoritário. Durante a Guerra Fria, os habitantes de países alinhados com o regime socialista soviético sofreram com as restrições mais gerais, como o cerceamento do direito de livre circulação, o controle da economia e a escassez de alimentos, mas também com uma constante ameaça de que houvesse uma guerra nuclear. Além disso, os cidadãos que por algum motivo eram denunciados como inimigos do Estado passavam a ser perseguidos pela polícia política, que os manipulava através de vigilância, de violência física e de desestabilização emocional. A atmosfera de repressão, o medo e a violência foram componentes de uma realidade perturbadora, que criou condições para a existência de um trauma cumulativo. O objetivo deste trabalho é verificar como estão representadas na literatura escrita após o fim da ditadura comunista a experiência traumática destes tempos e as estratégias de resistência ao trauma. Com esta finalidade, foram selecionadas três obras: O charuto apagado de Churchill, de Thomas Brussig; O rei branco, de György Dragomán; e O compromisso, de Herta Müller.As obras foram analisadas sob a luz de teóricos como Theodor W. Adorno, Michel de Certeau, Gaston Bachelard, Linda Hutcheon, Boris Uspenski, entre outros. Como nestes três romances o contexto histórico interfere de formas diferentes nas vidas das personagens, eles foram analisados em separado, para que fosse possível identificar, em cada um, os períodos de construção e internalização do trauma. Esta divisão permanece no capítulo final, em que é verificado o aspecto composicional das obras, levando em consideração o narrador e seu ponto de vista espaço-temporal, a organização da memória narrada e os espelhos deformantes através dos quais o período é revisitado. A partir destas análises, foi verificado que, embora apresentem algumas diferenças entre si, as narrativas estudadas trazem características que as aproximam e que podem ser consideradas representações específicas da literatura que enfoca o período da Guerra Fria.

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Souza, Arivaldo Santos de. "Licenciamento ambiental, energia e desenvolvimento: caso da usina hidrelétrica Jirau." reponame:Repositório Institucional do FGV, 2011. http://hdl.handle.net/10438/8115.

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This dissertation thesis examines the environmental licensing of a hydroelectric power plant in the Amazon Basin: 'Usina Jirau.' This starting point for this case study was an allegation that the Brazilian environmental licensing process for hydroelectric power plants slows down the Brazilian development. As an initial matter, I assumed that such an argument is partially mistaken. On the one hand there may be problems in the administrative procedures and in the institutional design and functioning of the environmental agency, IBAMA; but on the other hand, the entrepreneurs did not properly consider legal environmental rules during the planning process. To test this hypothesis, I attended specific meetings on the subject, conducted interviews with key actors in the process, and researched the issues raised in different courts by a variety of litigators. I also analyzed the environmental licensing procedures extensively and some other to understand the economic argument, its variations and the proponents of such ideas. Additionally, I explain how and which hypotheses were tested in my research. In part II, I discuss the environmental licensing economic content, put the environmental documents from both state and non-state players. This paper is divided into four separate parts, and a conclusion. In part I, I explain the research problem, the context surrounding the construction of Usina Jirau as well, discuss some key players, and demonstrate how licensing rules together, and assess how the two aforementioned perspectives relate to each other. In part III, I describe the IBAMA bureaucracy functions as a means of assessing if, as a public administration, it was inefficient in licensing Usina Jirau. Thus, I describe the IBAMA authority to license such entrepreneurship, its structure and ability to provide this service, and list other administrative branches and entrepreneurs’ obligations. Lastly, I identify what were the sensitive points in the environmental licensing dynamics, which may have offered obstacles to the process. In park IV, I discuss the supposed failures in the control system of administrative duties. In conclusion, I summarize the research key points, offer some suggestions to improve the environmental licensing process and establish the distinction between inefficiency and enforcement of environmental conservational legal rules. Usina Jirau is an exemplary case of how a licensing process does not slow down the Brazilian development, and it is also a calling for Brazil to modernize and rationalize its environmental regulatory framework.
Esse é o caso do licenciamento ambiental do aproveitamento hidrelétrico Jirau, parte do Complexo Hidrelétrico do Rio Madeira. O ponto de partida da pesquisa foi a alegação de que o licenciamento ambiental de usinas hidrelétricas atrapalha o desenvolvimento brasileiro. Para enfrentar o argumento mencionado, levantei a suspeita de que o mesmo está parcialmente equivocado. Se por um lado, há problemas no procedimento administrativo do licenciamento ambiental e na estrutura e funcionamento do órgão licenciador; por outro lado, os interessados no sucesso da obra fizeram o planejamento do empreendimento sem levar em consideração exigências legais relativas ao ambiente. Para confirmar ou negar minha suspeita, fiz um levantamento dos atos do processo administrativo e das ações judiciais movidas por diferentes partes referentes ao licenciamento da UHE Jirau, conduzi entrevistas semiestruturadas com algumas pessoas envolvidas nesse processo, e consultei documentos dos órgãos estatais relacionadas ao caso, bem como documentos dos consórcios de empresas que concorreram ao leilão de geração de energia. O caminho metodológico adotado me fez dividir o trabalho em quatro capítulos e uma conclusão. No primeiro capítulo, apresento o problema da pesquisa, explico qual é o contexto da construção da UHE Jirau, e menciono os principais atores envolvidos. Também explico o funcionamento do argumento enfrentado. Por fim, explico como e quais são as hipóteses que serão testadas: hipótese da falha no sistema de controle e hipótese da ineficiência do procedimento. No segundo capítulo, trato do sentido jurídico-econômico do licenciamento ambiental, mapeio as regras que disciplinam esse instrumento de política ambiental e mostro o funcionamento da teoria e das regras na prática do licenciamento da usina Jirau. No terceiro capítulo, descrevo o funcionamento da burocracia do órgão licenciador para avaliar se o licenciamento ambiental da usina hidrelétrica Jirau foi ineficiente. Assim, descrevo as competências, a estrutura e a capacidade de atendimento do órgão licenciador, bem como as obrigações do empreendedor e demais órgãos. Por fim, identifico quais foram os pontos sensíveis da dinâmica do licenciamento ambiental que podem ter eventualmente impedido a administração de cumprir prazos legais. No quarto capítulo, busco identificar eventuais falhas no sistema de controle do processo do licenciamento ambiental da UHE Jirau a partir dos embates administrativos e judiciais que ocorreram a partir da alteração do projeto da usina após a realização do leilão, assim como das inovações processuais ocorridas no caso. O capítulo derradeiro retoma os pontos chave da pesquisa; aponta caminhos para a melhoria do licenciamento ambiental de usinas hidrelétricas no âmbito do órgão federal; e indica algumas exigências próprias da natureza das leis de conservação ambiental, as quais não devem ser confundidas com fatores de produção de ineficiência do procedimento. O caso de Jirau não pode ser acusado de criar embaraços temporais à expansão da oferta da energia necessária para o desenvolvimento brasileiro em razão de burocracia excessiva e fragilidades institucionais do órgão. O temor de criminalização dos técnicos aumentou o grau de exigências e o sistema de controle administrativo e judicial expôs à sociedade questões do licenciamento sem fazer com que o mesmo demorasse ainda mais. Palavras-chave: Usina hidrelétrica Jirau. Licenças ambientais. Direito Ambiental. Desenvolvimento Econômico.

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22

Langdown, N. "South African gender-based violence researchers’ awareness and usage of bibliometrics and altmetrics in the context of open access scholarly publishing." University of the Western Cape, 2020. http://hdl.handle.net/11394/8115.

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Philosophiae Doctor - PhD
The traditional model of scholarly communication uses journals, databases, and conferences. With the onset of the digital age, there has been a change in the system of scholarly communication, creating new publishing models, such as open access and institutional repositories, which have emerged as important, scholarly communication models. The research questions addressed in this study investigated the value of using altmetrics, as opposed to traditional metrics for measuring the impact of publications by researchers into gender-based violence (GBV) within South Africa.

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Friedbaum, Samuel Searle. "Studies of Dislocation Density Quantification Via Cross-Correlation EBSD." BYU ScholarsArchive, 2019. https://scholarsarchive.byu.edu/etd/8115.

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One conventional method for studying dislocations uses the Transmission Electron Microscope (TEM), a complex and expensive piece of equipment which requires extensive specimen preparation in order to thin the specimens to electron transparent thickness. Newer High Resolution Electron Backscatter Diffraction (HREBSD) methods of determining geometrically necessary dislocation content via cross-correlation promise to be able to produce estimates of the dislocation density of the sample over a larger area with considerably less preparation time and using a much more accessible instrument. However, the accuracy of the new EBSD technique needs more experimental verification, including consideration of possible changes in the specimen dislocation density due to the different preparation methods. By comparing EBSD and TEM dislocation measurements of Electron Transparent platinum specimens prepared using the Focused Ion Beam (FIB), along with EBSD dislocations measurements of specimens prepared by both FIB and mechanical polishing techniques, this paper seeks to verify the accuracy of the new method and identify any changes in the specimens’ apparent dislocation density caused by the different preparation processes.

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24

Zimba, Machilu. "Design houses in the Cape Town clothing value chain of production." Master's thesis, University of Cape Town, 2008. http://hdl.handle.net/11427/8115.

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Includes abstract.
Includes bibliographical references (leaves 79-81).
This exploratory study aimed to investigate the role that design houses play in the Cape Town clothing value chain of production. Semi-structured interviews were conducted with key informants, buyers in clothing retail companies, heads of design rooms in design houses, and homeworkers. Findings reveal that design houses act as intermediaries between retailers and clothing manufacturers or between retailers and homeworkers. In their latter role design houses are forging links between the informal and formal clothing economy. As in buyer-driven chains of production, retailers in the clothing value chain wield a substantial amount of power in determining prices. It was found that design houses are not completely powerless in their relationship with retailers, in fact, they posses knowledge that enables them to bargain over prices. The relationship between design houses and homeworkers was found to be an oppressive one, with homeworkers possessing little to no bargaining power. The increase in the number of design houses in Cape Town has assisted in the survival of the industry in the face of a number of difficulties. The continued presence of design houses creates the potential for development in the industry.

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25

Arpi, Choque Verónica Vanessa. "Estudio de hidrología e hidráulica para el diseño del drenaje en el corredor vial puente Chagual – Retamas (La Libertad)." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2018. https://hdl.handle.net/20.500.12672/8115.

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El documento digital no refiere un asesor
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Realiza el estudio de hidrología e hidráulica para las obrasde drenaje vial puente Chagual - Retamas, localizada en la Provincia de Pataz departamento de La Libertad, lo cual permita en todo momento y de manera eficiente desalojar el escurrimiento, consecuencia de las precipitaciones. La vida útil de una vía generalmente está ligada al período de tiempo en el que el exceso de agua permanece en su estructura. Como un objetivo del drenaje es preservar la vía y prevenir al medio ambiente de un impacto negativo, se aborda el presente estudio con el fin de analizar, calcular y dimensionar las principales estructuras que componen un sistema de drenaje, tales como: alcantarillas, badenes y puentes.
Trabajo de suficiencia profesional

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26

Edwards, Thomas M. (Thomas Mark) 1974. "Nitric oxide-activated mechanisms underlying memory formation using a passive avoidance task for the day-old chick. Volume 1." Monash University, Dept. of Psychology, 2002. http://arrow.monash.edu.au/hdl/1959.1/8115.

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Meek, Richard William. "Structural and functional analysis of proteins involved in the C-DI-GMP network of the predatory bacterium Bdellovibrio bacteriovirus." Thesis, University of Birmingham, 2018. http://etheses.bham.ac.uk//id/eprint/8115/.

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Bdellovibrio bacteriovorus HD 100 is a σ-proteobacterium that predates on Gram-negative bacteria. The lifecycle of Bdellovibrio bacteriovorus is complex and regulated in part by the cyclic nucleotide, c-di-GMP. Gene knockouts of diguanylate cyclases reveal discrete phenotypes in Bdellovibrio at different time points of predation. This thesis presents the first structure of the Bdellovibrio diguanylate cyclase, Bd0742 in an inhibitory conformation. Bd0742 mediates invasion but the mechanism of its regulation was unknown. Our structure suggests that an N-terminal tail attached to the forkhead-associated domain of Bd0742 regulates diguanylate cyclase activity via self-binding. We present structural and biochemical evidence demonstrating that the Nterminal tail regulates Bd0742 activity. An active mutant of Bd0742 was produced by introduction of a disulphide bond. We also solved the structure of the glucose-6-phosphate isomerase Bd07 41. Bd07 41 likely catalyses isomerization of glucose-6-phosphate and of fructose-6-phosphate. Finally, this thesis presents a structure of a region of the degenerate diguanylate cyclase, Bd3125. Mutant strains deficient of Bd3125 invade prey more slowly. The Bd3125 structure reveals that a previously cryptic domain is a GAF (cGMP-specific phosphodiesterase, Adenylyl cyclases and FhiA) domain, with a potential role in controlling invasion speed.

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Lopes, Carlos Felipe Borges de Magalhães. "Sobre o Fundo Soberano do Brasil." reponame:Repositório Institucional da UnB, 2009. http://repositorio.unb.br/handle/10482/8115.

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Dissertação (mestrado)—Universidade de Brasília, Faculdade de Economia, Administração, Contabilidade e Ciência da Informação e Documentação, Departamento de Economia, Programa de Pós-Graduação em Economia, 2009.
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Este trabalho analisa o impacto de fundos de riqueza soberana de países exportadores de petróleo sobre a volatilidade macroeconômica doméstica. Foram feitas regressões econométricas sobre um painel de vinte e três países, no período de trinta e cinco anos que vai de 1973 a 2007. O trabalho também procura responder: 1) se fundos de riqueza soberana com desenhos institucionais melhores têm impactos mais positivos na economia, e 2) se estes fundos reduzem, por si mesmos, a volatilidade macroeconômica ou são apenas reflexos de outras instituições dos países onde estão sediados. _______________________________________________________________________________________ ABSTRACT
This work analyses the impact of sovereign wealth funds of petroleum exporting countries on domestic macroeconomic volatility. Econometric regressions were made on panel data of twenty three countries spanning a period of thirty five years from 1973 through 2007. The work also tests: 1) if sovereign wealth countries with better institutional settings achieve better results, and 2) if these funds tend to reduce by themselves macroeconomic volatility or if they just mirror other institutions of their countries.

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Dornelles, Fani. "ANÁLISE DA GESTÃO DOS TRATAMENTOS DOS EFLUENTES GERADOS NOS ABATEDOUROS DE BOVINOS DE SÃO LUIZ GONZAGA." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/8115.

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The slaughterhouses of bovines utilized great amounts of water. It can reach 2,500 liters by animal slaughtered, generating residuary waters carried with high organic loads and solid concentration in suspension. The solid residue production is also elevated. They are from animal excremental deposition in the transport trucks during the confinement which precedes the slaughter. And also from non-edible by-products originated from the industry process. The applications of environmental and quality management techniques have reduced the residue release in a significant way in the food industries, though this reduction limits itself to the necessary hygienization of their processes. Despite the advances, both the generation and the dumping of the waste without adequate fate utilizing mainly the water as vehicle. Finally, effluents are voluminous and represent a serious environmental problem. The current research had as focus to know the reality of the chief bovine slaughterhouses of São Luiz Gonzaga municipality in order to identify and analyze the methods adopted by slaughterhouses as the management of effluents produced in each of them. Firstly a bibliographical survey was carried out. Samples of effluents were collected and sent for laboratory analysis of the physical-chemical features in order to verify if they have the characteristics demanded in the the emission patterns. The slaughterhouse images were recorded and the managers and the officials interviewed for identifying the degree of perception of the responsibility in each category. This study characterizes itself as a field exploratory and descriptive research approached in a qualitative form. The result shows that the components of the analyzed enterprises understand the importance of an environmental management program, but don t adopt any model or methodology which fulfills to the requirement of Environmental Legislation and that shows clearly their participation and commitment with this issue.
Os abatedouros de bovinos utilizam grande quantidade de água podendo chegar a 2500 litros por animal abatido, gerando águas residuárias carreadas com altas cargas orgânicas e concentrações de sólidos em suspensão. É elevada também a produção de resíduos sólidos oriundos da deposição fecal dos animais nos caminhões de transporte, durante o confinamento que antecede ao abate e dos subprodutos não comestíveis provenientes do processo industrial. As aplicações de técnicas de gestão ambiental e gestão da qualidade têm reduzido de forma significativa a emissão de resíduos nas indústrias de alimentos, embora essa redução limite-se às necessidades de higienização de seus processos. Apesar dos avanços, ainda são elevados, tanto a geração, como o despejo de resíduos sem destino adequado, utilizando, principalmente, a água como veículo. Enfim, os efluentes são volumosos e representam um sério problema ambiental. A presente pesquisa teve por foco conhecer a realidade dos principais abatedouros de bovinos de São Luiz Gonzaga, para identificar e analisar os métodos adotados pelos abatedouros quanto à gestão dos efluentes produzidos em cada um deles. Inicialmente, foi realizada uma pesquisa bibliográfica, amostras dos efluentes foram coletadas e enviadas para análise laboratorial das características físico-químicas para verificar se atendem as exigências dos padrões de emissões. Registraram-se, também, imagens dos abatedouros, e os gestores e funcionários foram entrevistados para identificar o grau de percepção da responsabilidade ambiental em cada categoria. O estudo se caracteriza como uma pesquisa de campo exploratória e descritiva abordada de forma qualitativa. O resultado demonstra que os integrantes das empresas analisadas compreendem a importância de um programa de gestão ambiental, mas não adotam nenhum modelo ou metodologia que atenda aos requisitos da Legislação Ambiental e que evidencie a participação e comprometimento deles com esta questão.

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Oliveira, Fernando Calzavara de. "Implementação da rede de atenção psicossocial (RAPS) no contexto na política de saúde mental do município de São Carlos/SP (2010-2015)." Universidade Federal de São Carlos, 2016. https://repositorio.ufscar.br/handle/ufscar/8115.

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The Ordinance No. 3088, of December 23, 2011, establishes the framework the Unified Health System (SUS) and the mental health policy in Brazil formation guideline and implementation of psychosocial care network .Considering the need for the SUS: 1) encourage the formation of a network integrated, coordinated and effective mental health in different parts of attention to meet people with suffering or mental disorder and needs arising from the consumption of alcohol, crack and other drugs; besides 2) expand and diversify the provision of services to the same population, we seek through this research to analyze to what extent and how this policy is being implemented in the context of mental health policy of São Carlos city at São Paulo State. However, the objective of the study was to verify whether they are being implemented innovative means of intersectoral management, integrated and articulated, that confer efficacy to psychosocial care, along the lines adopted by SUS for mental health, and identify what are these possible mechanisms in order to make recommendations for procedures the gain in efficiency of decentralized management of this policy can be replicated in other cities depending on the higher or lower specificities and obstacles discovered. From the identification fragmentation characteristics of the same during the process of implementation, it was possible to create a picture in order to identify possible variables related to this current configuration. The methodology used was embedded single case study (Yin, 2005), and data collected through empirical observation, semi structured interview script application with managers who coordinate services and agents implementers, and through documentary survey of the records Psychosocial Care Center Alcohol and Drugs- CAPS AD from Sao Carlos city, between 2010 the 2012. Finally, we concluded that the implementation of RAPS policy in São Carlos city is weakened because of: 1) his condition current training, 2) the effects on structuring of the different models of mental health care that overlap, and 3) the action actors who produces conflict and not cooperation.
A Portaria de no 3088, de 23 de Dezembro de 2011, estabelece no âmbito do Sistema Único de Saúde (SUS) e da política de saúde mental no Brasil a diretriz deformação e implementação da rede de atenção psicossocial. Considerando a necessidade de que o SUS: 1) incentive a formação de uma rede de saúde mental integrada, articulada e efetiva nos diferentes pontos de atenção para atender as pessoas com sofrimento ou transtorno mental e com necessidades decorrentes do consumo de álcool, crack e outras drogas; bem como 2) amplie e diversifique a oferta de serviços para esta mesma população, buscamos por meio desta pesquisa analisar em que medida e de que modo esta política vem sendo implementada no contexto da política de saúde mental do município de São Carlos-SP.Portanto, o objetivo do estudo foi verificar se estão sendo implementados meios inovadores de gestão intersetorial, integrada e articulada, que confiram eficácia à atenção psicossocial, nos moldes preconizados pelo SUS para a saúde mental, e identificar quais são estes possíveis mecanismos, a fim de produzir recomendações de procedimentos para o ganho de eficácia da gestão descentralizada desta política que possam ser replicados em outros municípios, a depender das maiores ou menores especificidades e empecilhos encontrados.Em face da identificação de características de fragmentação da mesma durante o processo de implementação, foi possível criar um retrato, a fim de se identificar possíveis variáveis relacionadas a essa configuração atual. A metodologia utilizada foide estudo de caso único incorporado, (YIN, 2005), e os dados coletados através de observação empírica, da aplicação de roteiro de entrevista semi estruturada com os gestores que coordenam os serviços, bem como agentes implementadores;e por meio de pesquisa documental junto aos prontuários do Centro de Atenção Psicossocial - CAPS AD São Carlos, entre os períodos de 2010 a 2012.Com isso, concluímos que a implementação da política da RAPS no município de São Carlos encontra-se fragilizada em virtude:1) de sua condição atual de formação, 2) dos efeitos em sua estruturação dos diferentes modelos de cuidado em saúde mental que se sobrepõem, bem como 3) da ação de atores que produzem como resultado o conflito e não a cooperação.

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Hodge, Thomas Wolf Stephen. "Hyperkähler geometry and Teichmüller space." Thesis, Imperial College London, 2005. http://hdl.handle.net/10044/1/8115.

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We consider the hyperkähler extension of Teichmüller space with the Weil-Petersson metric. We describe its recent construction as a hyperkähler quotient and examine the defining equations for the resulting moduli space. We examine relations between this moduli space and the quasi-Fuchsian deformation space of the surface, with particular attention to the connection with the canonical holomorphic symplectic structure. We also consider the connection with Taubes moduli space of hyperbolic germs and whether it is possible to extend the hyperkähler structure in any fashion.

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Brion, Nicolai Henrique Dianim. "A Releitura de O Leão, a Feiticeira e o Guarda-Roupa no Cinema." www.teses.ufc.br, 2013. http://www.repositorio.ufc.br/handle/riufc/8115.

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BRION, Nicolai Henrique Dianim. A Releitura de O Leão, a Feiticeira e o Guarda-Roupa no Cinema. 2013. 114f. – Dissertação (Mestrado) – Universidade Federal do Ceará, Programa de Pós-graduação em Letras, Fortaleza (CE), 2013.
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The Lion, the Witch and the Wardrobe (1950), by C. S. Lewis, is a typical fantasy narrative. Thus, its form and contents are shaped by characteristics which have traditionally marked the genre, such as the appeal to a medieval atmosphere. The story was adapted to the Hollywood cinema by Andrew Adamson in 2005 keeping the same title. The main goal of this dissertation is to discuss the strategies employed by the director to produce an action blockbuster in the format of the classical Hollywood narrative through the exploration of the fantastic and medieval elements of the novel. It starts from the idea that the film adaptation, although it comes from a text which occupies a peripheral position in the British literary system, manages to stand out in the Hollywood cinematographic system. This research is descriptive and has a qualitative approach, which consists of the reading of both the novel and the film to analyse how fantasy and medievalism are configured in these narratives. The analysis led us to conclude that the adaptation was able to resignify the elements of the novel which are responsible for its marginalization. The theoretical bases for this work are the principles of the descriptive translation studies, especially the concept of rewriting, by Lefevere (2007), and the premises of the polysystem theory, by Even-Zohar (1990). Theoretical references still include Todorov (2010, 2006) and Propp (2006), to characterize the novel as a fantasy narrative; Cecire (2009) and Hobsbawm (1997), to approach the matter of medievalism; Compagnon (1999) and Wellek and Warren (2003), to discuss the literary canon; and Bordwell (1985), to delimitate the properties of the classical Hollywood narration pattern.
O Leão, a Feiticeira e o Guarda-Roupa (1950), de C. S. Lewis, é uma típica narrativa de fantasia. Assim, apresenta características de forma e conteúdo que têm sido tradicionalmente empregadas pelo gênero, entre elas o apelo a uma atmosfera medieval. A história foi adaptada para o cinema de Hollywood em 2005 por Andrew Adamson, com título homônimo. O objetivo principal desta dissertação é discutir as estratégias utilizadas pelo diretor para produzir um blockbuster de ação no formato da clássica narrativa hollywoodiana, explorando os elementos fantásticos e medievais da obra. Parte-se da ideia de que a adaptação, embora oriunda de um texto que ocupa um espaço periférico no sistema literário britânico, consegue se destacar no sistema cinematográfico de Hollywood. A pesquisa tem caráter descritivo, com abordagem qualitativa, que consiste na leitura da obra literária e do filme para analisar como a fantasia e o medievalismo são configurados nessas narrativas. A análise levou-nos a concluir que a adaptação foi capaz de ressignificar os elementos da obra literária responsáveis por sua marginalização. Como base teórica, apoia-se nos princípios dos estudos descritivos de tradução, sobretudo no conceito de reescritura, de Lefevere (2007), e nos pressupostos da teoria dos polissistemas, de Even-Zohar (1990). Os referenciais teóricos ainda incluem Todorov (2010, 2006) e Propp (2006), para caracterizar a obra como uma narrativa de fantasia; Cecire (2009) e Hobsbawm (1997), para abordar a questão do medievalismo; Compagnon (1999) e Wellek e Warren (2003), para discutir o cânone literário; e Bordwell (1985), para delimitar as propriedades do padrão narrativo clássico de Hollywood.

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SANDOVAL, N. G. "MMP-2 Atua no Desenvolvimento Dentário e na Remodelação Óssea Durante a Erupção Dentária." Universidade Federal do Espírito Santo, 2016. http://repositorio.ufes.br/handle/10/8115.

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À medida que o processo de odontogênese avança, dando início à deposição de tecidos mineralizados da coroa, ocorre de forma paralela o processo de erupção dentária, que permite ao dente atravessar as barreiras teciduais que o circundam até que ele possa emergir na cavidade oral. Esse processo envolve a degradação da lâmina própria e a reabsorção da parte superior da cripta óssea que envolve o dente por ação de metaloproteinases (MMPs).O objetivo desta pesquisa foi identificar a expressão de MMP-2 em germes dentários de molares de ratos e nos tecidos circunjacentes ao longo do processo eruptivo. A detecção de MMP-2 foi realizada por imuno-histoquímica em 24 amostras de animais com idades entre 04 a 16 dias. A expressão de MMP-2 foi bservada no tecido ósseo basal e apical e em regiões do germe dentário: papila dentária, ameloblastos, odontoblastos, retículo estrelado efolículo dentário. Os esultados desta pesquisa indicam que a forte expressão de MMP-2 em ameloblastos e odontoblastos pode indicar um papel dessa enzima nos processos de síntese, mineralização e maturação dos tecidos mineralizados do dente. Por outro lado, a expressão de MMP-2 no folículo dentário e osso ao redor do germe podem indicar a participação de MMP-2 nos processos de remodelação óssea necessários para o prosseguimento do processo de erupção dentária.

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Cauás, de Queiroz Gatis Michelly. "Disfunção craniomandibular, migrânea e cefaléia do tipo tensional: influência na qualidade de vida." Universidade Federal de Pernambuco, 2010. https://repositorio.ufpe.br/handle/123456789/8115.

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Introdução: A disfunção craniomandibular (DCM) é um termo coletivo para os problemas clínicos que envolvem a musculatura da mastigação, a articulação temporomandibular (ATM) e as estruturas anexas. A cefaleia é um sintoma que aparece frequentemente associado à DCM, onde estas entidades nosológicas conjugadas ou em separado podem causar danos à qualidade de vida. Objetivo: Verificar se a DCM e a cefaleia influênciam na qualidade de vida. Métodos: O estudo transversal observacional analítico foi composto de uma população de 128 funcionários de ambos os sexos, 57,8% do sexo masculino, de um Hospital Militar de Recife-PE, com média de idade de 34 anos. Os funcionários voluntariamente responderam ao questionário divido em três fases: a primeira baseada no Índice Anaminésico de Fonseca para DCM; a segunda de acordo com os Critérios da Sociedade Internacional de Cefaleia para migrânea e cefaleia do tipo tensional (CTT); e a terceira, avaliação da qualidade de vida com o Whoqol-breef. Para análise dos dados foram utilizados os testes t-Student com variâncias iguais ou desiguais, o de Tukey para comparações múltiplas pareadas de Levene para verificação da hipótese de igualdade de variâncias, para os cálculos estatísticos foi o Statistical Package for the Social Sciences e ANOVA. O nível de significância foi de 5,0%. Resultados: A faixa etária mais prevalente no estudo foi entre 30 e 39 anos, com predominânica para o sexo feminino. Para DCM as caracteristicas clínicas mais prevalentes foram estresse (n=53), torcicolo ou dor na boca (n=43), ruídos na aticulação temporomandibular (n=37), apertamento dentário ou bruxismo (n=36) e cefaleia (n=35). Já para a cefaleia, foi dores de cabeça episódica 27,3%; caráter pulsátil 24,2%; fotofobia e fonofobia 21,1% e 20,3% localização bilateral. Em que 15,6% apresentavam DCM e cefaleia, porém, a presença de DCM foi aproximadamente, cinco vezes maior, exercendo assim, uma maior influência na qualidade de vida sob a ótica do Whooqol breef. Conclusão: Concluiu-se que a presença de DCM interfere significantemente na qualidade de vida dos indivíduos

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35

Taylor, Desta A., Stacey L. Williams, and D. McKelvey. "The College Student Stigma Study." Digital Commons @ East Tennessee State University, 2011. https://dc.etsu.edu/etsu-works/8115.

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36

Pawi, Alipah. "Modelling and extraction of fundamental frequency in speech signals." Thesis, Brunel University, 2014. http://bura.brunel.ac.uk/handle/2438/8115.

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One of the most important parameters of speech is the fundamental frequency of vibration of voiced sounds. The audio sensation of the fundamental frequency is known as the pitch. Depending on the tonal/non-tonal category of language, the fundamental frequency conveys intonation, pragmatics and meaning. In addition the fundamental frequency and intonation carry speaker gender, age, identity, speaking style and emotional state. Accurate estimation of the fundamental frequency is critically important for functioning of speech processing applications such as speech coding, speech recognition, speech synthesis and voice morphing. This thesis makes contributions to the development of accurate pitch estimation research in three distinct ways: (1) an investigation of the impact of the window length on pitch estimation error, (2) an investigation of the use of the higher order moments and (3) an investigation of an analysis-synthesis method for selection of the best pitch value among N proposed candidates. Experimental evaluations show that the length of the speech window has a major impact on the accuracy of pitch estimation. Depending on the similarity criteria and the order of the statistical moment a window length of 37 to 80 ms gives the least error. In order to avoid excessive delay as a consequence of using a longer window, a method is proposed ii where the current short window is concatenated with the previous frames to form a longer signal window for pitch extraction. The use of second order and higher order moments, and the magnitude difference function, as the similarity criteria were explored and compared. A novel method of calculation of moments is introduced where the signal is split, i.e. rectified, into positive and negative valued samples. The moments for the positive and negative parts of the signal are computed separately and combined. The new method of calculation of moments from positive and negative parts and the higher order criteria provide competitive results. A challenging issue in pitch estimation is the determination of the best candidate from N extrema of the similarity criteria. The analysis-synthesis method proposed in this thesis selects the pitch candidate that provides the best reproduction (synthesis) of the harmonic spectrum of the original speech. The synthesis method must be such that the distortion increases with the increasing error in the estimate of the fundamental frequency. To this end a new method of spectral synthesis is proposed using an estimate of the spectral envelop and harmonically spaced asymmetric Gaussian pulses as excitation. The N-best method provides consistent reduction in pitch estimation error. The methods described in this thesis result in a significant improvement in the pitch accuracy and outperform the benchmark YIN method.

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37

Röhn, Oliver. "Three Empirical Essays on the Determinants of Economic Growth." Diss., lmu, 2008. http://nbn-resolving.de/urn:nbn:de:bvb:19-81150.

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Classon, Gustaf, and Daniel Åberg. "Afasi och luktförmåga." Thesis, Linköpings universitet, Logopedi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-81159.

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Att perceptuellt uppfatta och identifera lukter påverkas av en rad olika kortikala system och kognitva förmågor. Syftet med föreliggande studie var att undersöka huruvida personer med afasi har en luktförmåga som skiljer sig från normalpopulationen och ifall en afasiproblematik påverkar de faktorer som normalt involverar luktförmågan. I studien medverkade tio försökspersoner, sex män och fyra kvinnor. Personerna hade varierande grad och typ av afasi och var mellan 42 och 76 år. Deltagarna delades in i åldersgrupper där två personer klassades som yngre och åtta som äldre. Samtliga testdeltagare genomförde två olika lukttest: Odor Threshold Test (OTT), och Swedish Odor Identification Test (SOIT). Testdeltagarnas journaler granskades även för information om skadehistoria samt livsvanor. Resultaten visade att 60% av deltagarna hade en nedsatt luktförmåga och att det fanns större resultatskillnader i SOIT än OTT då kön och förekomst/avsaknad av epilepsi testades mot varandra. Inga resultat kunde dock styrkas med statistisk signifikans jämfört med en normalpopulation eller inom gruppen.

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Santos, Lucineide de Melo. "Diagnóstico de cárie oclusal e decisão de tratamento em molares decíduos :: variação entre examinadores /." Florianópolis, SC, 1999. http://repositorio.ufsc.br/xmlui/handle/123456789/81150.

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Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde.
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O objetivo deste estudo foi avaliar em um grupo de examinadores não calibrados a concordância quanto ao diagnóstico e à decisão de tratamento de cárie oclusal realizados sem e com o auxílio de raio X interproximal. Foi encontrada ampla variação entre os examinadores quanto aos diagnósticos e às decisões de tratamento sem e com a utilização do raio X interproximal. O uso do raio X interproximal não alterou significativamente os diagnósticos realizados pelos examinadores e os achados no estereomicroscópio.

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Volpato, Gildo. "O jogo, a brincadeira e o brinquedo no contexto sócio-cultural criciumense /." Florianópolis, SC, 1999. http://repositorio.ufsc.br/xmlui/handle/123456789/81151.

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Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Desportos.
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Negreiros, Paulo César de Araújo. "Programa de qualidade e comprometimento organizacional: o caso do SEBRAE-AM." Florianópolis, SC, 1999. http://repositorio.ufsc.br/xmlui/handle/123456789/81153.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico
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A presente pesquisa, intitulada Programa de Qualidade e Comprometimento Organizacional: o caso do SEBRAE-AM, buscou ouvir a opinião dos funcionários (denominados internamente de colaboradores) do SEBRAE-AM sobre qualidade e comprometimento, e teve como objetivos: a) avaliar como os funcionários percebem a qualidade ; b) investigar quanto da qualidade os funcionários esperam; c) pesquisar os níveis de comprometimento dos funcionários; e d) investigar quanto eles acham que devem se esforçar para obter índices de qualidade relativamente maiores do que os concorrentes.

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Carvalho, Raquel Baroni de. "Análise estrutural da junção amelocementária dos dentes decíduos em microscopia eletrônica de varredura /." Florianópolis, SC, 1999. http://repositorio.ufsc.br/xmlui/handle/123456789/81154.

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Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde.
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Antoniolli, Marinez Amabile. "Vida útil do mexilhão Perna perna (L.) processado e mantido sob refrigeração /." Florianópolis, SC, 1999. http://repositorio.ufsc.br/xmlui/handle/123456789/81155.

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Ruiz, Caballero Domingo Antonio. "Novo conversor CC-CC flyback-push-pull alimentado em corrente :." Florianópolis, SC, 1999. http://repositorio.ufsc.br/xmlui/handle/123456789/81156.

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Tese (Doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico.
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Maccari, Danilo. "Formação de células de manufatura através da metodologia Branch and Bound /." Florianópolis, SC, 1999. http://repositorio.ufsc.br/xmlui/handle/123456789/81157.

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Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.
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A crescente concorrência no mercado mundial, juntamente com a globalização e diversificação dos produtos, tem obrigado as indústrias a abandonarem a filosofia de produção em massa, amplamente explorada nas décadas passadas e adotar sérias medidas de economia, redução de custos, qualidade de produto e flexibilidade.

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Sbruzzi, Liane. "Centro de Tecnologia em Cerâmica: um estudo de caso sobre cooperação universidade-empresa /." Florianópolis, SC, 1999. http://repositorio.ufsc.br/xmlui/handle/123456789/81158.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico.
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As relações entre universidades e o setor empresarial, por meio de instituições-ponte, criam forte base para o desenvolvimento tecnológico e para a capacidade de inovação das empresas. Sob esta perspectiva realizou-se um estudo sobre o Centro de Tecnologia em Cerâmica, localizado em Criciúma, considerado um exemplo de instituição-ponte, cuja constituição decorre de um arranjo envolvendo a Federação das Indústrias de Santa Catarina - FIESC, através do Serviço Nacional de Aprendizagem Industrial - SENAI; a Universidade Federal de Santa Catarina - UFSC, representada pelo Laboratório de Materiais - LabMat, o Governo do Estado de Santa Catarina, através da Fundação de Ciência e Tecnologia - FUNCITEC, e as Indústrias Cerâmicas, lideradas pelo Sindicato das Indústrias de Cerâmica para Construção e Olarias de Criciúma - SINDICERAM. Este Centro de Tecnologia em Cerâmica tem contribuído para criar, transferir e difundir tecnologias para o desenvolvimento da capacitarão tecnológica da Indústria Cerâmica e tem se constituído em instância representativa voltada para o estabelecimento de um sistema localizado de inovação na região sul de Santa Catarina. Neste sentido tem possibilitado ao setor industrial cerâmico demandar serviços tecnológicos em termos de caracterização minerológica, fisica e química de matérias-primas, caracterização e ensaios de certificarão da qualidade de produtos acabados, melhoria de processos de fabricação, formulação de composições cerâmicas para massas e esmaltes e análise de defeitos.

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Seifriz, Ilana. "Síntese, investigação eletroquímica, titulação potenciométrica e estudos farmacológicos do trans-diclorotetraquis-(3,5-dicarboxipiridina) rutênio (II)." Florianópolis, SC, 1999. http://repositorio.ufsc.br/xmlui/handle/123456789/81159.

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Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Curso de Pós-Graduação em Química
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Este trabalho relata síntese, a caracterização espectroscópica, a titulação potenciométrica, a investigação eletroquímica e o estudo das propriedades biológicas do complexo trans-[RuCl2(dinic)4] (dinic= ácido piridinadicarboxílico). O complexo foi sintetizado utilizando-se uma solição de azul de rutênio como precursor da rota sintética. O composto foi caracterizado por análise elementar, espectroscopia eletrônica, espectroscopia FT-IR, espectroscopia Raman e de RMN de 1H e 13C. Os resultados indicaram que o complexo apresenta geometria trans com simetria D4h. Experimentos de Voltametria Cíclica foram conduzidas em uma solução binária água/acetona 1:1, revelando um processo quasi-reversível centrado no átomo de rutênio, bem como uma dependência do potencial redox (E1/2) com o pH. O espectro eletrônico revelou uma banda de transferência de carga metal ligante (MLCT), a qual apresentou um deslocamento hiposocrômico com o aumento do pH. As análises espectroeletroquímicas indicaram que a banda na região do UV-Visível desapareceu progressivamente durante o processo de oxidação. Estudos potenciométricos revelaram a presença de 16 espécies em solução, cujas constantes de protonação foram determinadas. O complexo exibiu ainda a habilidade de complexar íons cálcio. O complexo estudado não exibiu a atividade da enzima óxido nítrico sintase e também não atuou como captador de monóxido de nitrogênio. Entretanto, o complexo mostrou propriedades antinociceptivas e foi capaz de captar radicais hidroxilas.

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48

Sandell, Viktor. "Defects in E-PBF Ti-6Al-4V and their Effect on Fatigue Behaviour : Characteristics, Distribution and Impact on Life." Licentiate thesis, Luleå tekniska universitet, Materialvetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:ltu:diva-81155.

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Layer by layer manufacturing (additive manufacturing, AM) of metals is emerging as an alternative to conventional subtractive manufacturing with the goal of enabling near net-shape production of complex part geometries with reduced material waste and shorter lead times. Recently this field has experienced rapid growth through industrial adaptation but has simultaneously encountered challenges. One such challenge is the ability of AM metal to withstand loading conditions ranging from static loads to complex multiaxial thermo-mechanical fatigue loads. This makes fatigue performance of AM materials a key consideration for the implementation of AM in production. This is especially true for AM in the aerospace industry where safety standards are strict. Defects in metal AM materials include rough surfaces, pores and lack-of-fusion (LOF) between build layers. These defects are detrimental to fatigue as they act as local stress concentrators that can give rise to cracks in the material. Some defects can be avoided by careful build process optimization and/or post-processing but fully eliminating all defects is not possible. Because of this, a need arises for the capability to estimate the fatigue performance of AM produced critical components containing defects. The aim of the thesis is to increase understanding regarding the connection between defect characteristics and the fatigue behaviour in AM produced Ti-6Al-4V. Defect distributions are statistically analysed for use in a simple fracture mechanical model for fatigue life prediction. Other study areas include the impact of post-production treatments such as chemical surface treatments and hot isostatic pressing (HIP) on defects and fatigue behaviour. The thesis constitutes three scientific papers. The AM technique studied in these papers is Electron Beam Melting (EBM) in which an electron beam selectively melts pre-alloyed metal powder. In paper 1, defects were studied using X-ray computed tomography (XCT) and fatigue crack initiation was related to the observed defect distribution. In paper 2, XCT data was used to relate the surface morphology and roughness of post-production treated EBM material to the surface near defect distribution. The connection between this distribution and manufacturing parameter has also been explored. Paper 3 builds on and extends the work presented in paper 1 by including further fatigue testing as well as a method for predicting fatigue life using statistical analysis of the observed defect distribution. The impact of a defect on the fatigue behaviour of the material was found to largely depend on its characteristics and position relative to the surface. Production and post-processing of the material was found to play a role in the severity of this impact. Finally, it was found that a probabilistic statistical analysis can be used to accurately predict the life of the studied material at the tested conditions.
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49

Lindahl, Sofia, and Erica Lindgren. "Hur har arbetet med intern kontroll förändrats? : En studie av några svenska bolag." Thesis, Uppsala University, Department of Business Studies, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8115.

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Syftet med uppsatsen är att följa upp tre svenska bolags syn på hur det praktiska arbetet samt ansvarsfördelningen avseende intern kontroll har förändrats och utvecklats de senaste åren.

Det görs en jämförelse över tid av arbetet i vartdera bolaget för att sedan jämföra om arbetet i de olika bolagen skiljer sig åt. Det ska vidare diskuteras vad de eventuella skillnaderna kan bero på.

Intern kontroll är den del av bolagsstyrning som syftar till att säkerställa att uppsatta mål inom företagen uppnås samt motverka att fel begås i det dagliga arbetet. Intern kontroll har fått stor uppmärksamhet i media under de senaste åren på grund av att en rad bolagsskandaler har förekommit, både utomlands och i Sverige. I Sverige har bolagsstyrningsfrågorna stått högt på dagordningen under en längre tid. I september 2002 beslutade regeringen att tillsätta en kommission för att analysera behovet av åtgärder som säkerställer förtroendet för svenskt näringsliv. Brister i den svenska bolagsstyrningen identifierades och för att komma till rätta med dessa problem beslutades att införa ett nytt regelverk för bolagsstyrning i Sverige kallat Svensk kod för bolagsstyrning. Tillämpande av Svensk kod för bolagsstyrning är ett noteringskrav på Börsen och ska tillämpas av noterade bolag efter ”följa eller förklara”-principen. Detta innebär att ett bolag som tillämpar Koden måste redovisa och motivera eventuella avvikelser från den. Det finns även onoterade bolag som har valt att följa Koden.

Kritik har riktats mot Svensk kod för bolagsstyrning där ett argument gäller risken för att ett alltför stort fokus på intern kontroll inom bolagen leder till att de och deras styrelser ägnar mer tid åt efterlevnad av regler än affärer. Har införandet av utförlig rapportering om de interna kontrollerna tagit för mycket resurser och tid i anspråk? Det har sedan länge tillbaka funnits regelverk och lagar som reglerar den finansiella rapporteringen och bolagsstyrning inom företagen. Hur har de hårdare kraven på intern kontroll förändrat det arbete som har utförts för att följa tidigare befintliga regleringar?

De företag vi har valt för denna studie har medvetet valts ur tre vitt skilda branscher. Vår avsikt var att titta på bolagen enskilt och se hur deras eget arbete med intern kontroll avseende den finansiella rapporteringen har förändrats för att sedan jämföra denna förändring företagen emellan. De intervjuade bolagen är: Länsförsäkringar Liv, Hufvudstaden samt Clas Ohlson.

Vi har kommit fram till att Koden verkar för att öka tillförlitligheten för jämförbarheten mellan företagen genom att säkerställa kvaliteten på den finansiella rapporteringen. De frågor som rör intern kontroll har fått större fokus inom bolagen, de tillåts få en större budget och det inrättas tjänster för att se till att arbetet och hanteringen utav dess dokumentering ska ske korrekt. Rapporteringen har förändrats, det rapporteras mer utförligt, oftare och mer detaljerat än vad det gjordes tidigare i alla bolagen. Vi kan se likheter mellan bolagens svar och drar därför slutsatsen att det gemensamma draget för förändringen av intern kontroll inom bolaget gäller implementeringen av Svensk kod för bolagsstyrning och stora satsningar på att dokumentationen av arbetet ska fungera. Mycket av det arbete som nu dokumenteras utförligt genom hela bokslutsprocessen har redan funnits på plats i bolagen men en stor skillnad mot tidigare är att arbetet nu sker mer systematiskt.

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50

Drexler, Guido. "Etablierung eines neuen Rekombinations-Meßsystems und Nachweis der Störung homologer Rekombination in Atm- und Rad51C-defizienten Säugerzell-Mutanten." Diss., lmu, 2002. http://nbn-resolving.de/urn:nbn:de:bvb:19-8115.

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Dissertations / Theses on the topic '8115c'

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