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Journal articles on the topic '86.80 1008'

Author: Grafiati

Published: 12 December 2022

Last updated: 31 July 2025

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1

Myakinin, O. O. "Biomedical Data Analysis Systems for the Diagnosis of Skin Neoplasms." Journal of the Russian Universities. Radioelectronics 23, no. 3 (2020): 80–92. http://dx.doi.org/10.32603/1993-8985-2020-23-3-80-92.

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Introduction. The effectiveness of the diagnosis of malignant neoplasms of the skin remains unsatisfactory due to the complex process of interpretation of clinical features. On the other hand, in the last two decades, noninvasive optical diagnostic methods have been actively developed, for example, digital dermatoscopy for visualization of surface neoplasms and Optical Coherence Tomography (OCT) for obtaining spatial scans. Recent advances in the study of non-invasive diagnostic tools makes this area very promising for research in a clinical condition. Aim. Developing of software modules based

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Nakayama, Don K., and Spence M. Taylor. "SESC Practice Committee Survey: Surgical Practice in the Duty-hour Restriction Era." American Surgeon 79, no. 7 (2013): 711–15. http://dx.doi.org/10.1177/000313481307900716.

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Debate continues as to the relevance of Accreditation Council for Graduate Medical Education (ACGME) duty-hour restrictions in actual practice and the adequacy of resident training in surgery. A survey of the membership of the Southeastern Surgical Congress using an Internet-based questionnaire was conducted: adherence to duty-hour restrictions, evidence of sleepiness and fatigue, opinions regarding the training, and clinical performance of surgeons who had trained after the institution of duty-hour restrictions in 2003 (termed “recently trained surgeons”). One hundred seventy-seven members re

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Takahashi, Yoichi, and Hidetoshi Akiyama. "Heat capacity of gold from 80 to 1000 K." Thermochimica Acta 109, no. 1 (1986): 105–9. http://dx.doi.org/10.1016/0040-6031(86)85012-2.

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Azis, Huzain, Purnawansyah Purnawansyah, Farniwati Fattah, and Inggrianti Pratiwi Putri. "Performa Klasifikasi K-NN dan Cross Validation Pada Data Pasien Pengidap Penyakit Jantung." ILKOM Jurnal Ilmiah 12, no. 2 (2020): 81–86. http://dx.doi.org/10.33096/ilkom.v12i2.507.81-86.

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Globally, the number one cause of death each year is cardiovascular disease. Cardiovascular disease is a disease caused by impaired function of the heart and blood vessels, such as coronary heart disease, heart failure or heart failure, hypertension and stroke. The purpose of this study was to measure the performance of accuracy, precision, recall and f-measure of the K-NN and Crossvalidation methods on a dataset of cardiovascular patients. The dataset used was 1000 records consisting of 11 attributes (age, gender, height, etc.) cardiovascular and non cardiovascular patient data, the dataset w

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Barreira, Tiago V., Robert M. Brouillette, Heather C. Foil, Jeffrey N. Keller, and Catrine Tudor-Locke. "Comparison of Older Adults’ Steps per Day Using an NL-1000 Pedometer and Two GT3X+ Accelerometer Filters." Journal of Aging and Physical Activity 21, no. 4 (2013): 402–16. http://dx.doi.org/10.1123/japa.21.4.402.

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The purpose of this study was to compare the steps/d derived from the ActiGraph GT3X+ using the manufacturer’s default filter (DF) and low-frequency-extension filter (LFX) with those from the NL-1000 pedometer in an older adult sample. Fifteen older adults (61–82 yr) wore a GT3X+ (24 hr/day) and an NL-1000 (waking hours) for 7 d. Day was the unit of analysis (n= 86 valid days) comparing (a) GT3X+ DF and NL-1000 steps/d and (b) GT3X+ LFX and NL-1000 steps/d. DF was highly correlated with NL-1000 (r= .80), but there was a significant mean difference (–769 steps/d). LFX and NL-1000 were highly co

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Palinggi, Marselina, and Chaerun Nisa Tamsil. "ANALISIS FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN HIPERTENSI DI WILAYAH PUSKESMAS BANGGAE II KABUPATEN MAJENE." Jambura Journal of Health Sciences and Research 5, no. 2 (2023): 519–32. http://dx.doi.org/10.35971/jjhsr.v5i2.18467.

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Hipertensi yaitu salah satu penyakit yang masih sangat serius didunia, dan jarang sekali menimbulkan gejala serta tanda yang spesifik, dengan itulah penyakit hipertensi dikenal dalam sebutan silent disease atau silent killer karena pada umumnya masih jarang sekali penderita menyadari bahwa dirinya mengidap penyakit hipertensi hingga penderita mengontrol tekanan darahnya. Oleh dari itu tujuan akan penelitian ini ialah untuk mengetahui hubungan sikap dan motivasi terhadap kepatuhan minum obat pada penderita hipertensi. Pada penelitian ini hipertensi dilihat berdasarkan jenis hipertensi dari 120/

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Woodford, Joanne, Anna Wikman, Kim Einhorn, et al. "Attitudes and Preferences Toward a Hypothetical Trial of an Internet-Administered Psychological Intervention for Parents of Children Treated for Cancer: Web-Based Survey." JMIR Mental Health 5, no. 4 (2018): e10085. http://dx.doi.org/10.2196/10085.

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Background Clinical trials are often challenged with issues of recruitment and retention. Little is known concerning general attitudes and preferences toward trial design and willingness to participate among parents of children treated for cancer. Furthermore, willingness to participate in internet-administered psychological interventions remains unexplored. In this study, we examined attitudes and preferences of the population regarding study procedures for a hypothetical trial of an internet-administered psychological intervention. In addition, differences in the response rate between modes

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Schwegler and Puric. "Korrelation von Risikofaktoren mit angewandten Therapien bei brusterhaltend behandelten Mammakarzinomen." Praxis 92, no. 14 (2003): 639–48. http://dx.doi.org/10.1024/0369-8394.92.14.639.

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1007 brusterhaltend operierte Patientinnen mit Mammakarzinom wurden inkl. Boost mit median 66 (50–80) Gy ergänzend bestrahlt. 34.6% (348/1007) erhielten keine weitere Behandlung, 53.4 % (538/1007) Antihormone, 26% (262/1007) Zytostatika ± Tamoxifen. Alle Tumoren waren auf der Basis pathologisch-anatomischer Berichte klassiert: 70.7% (712/1007) pT1a–c, 27.4% (276/1007) pT2, 1.9% (19/1007) pT3–4: Verweigerung der Mastektomie bzw. prätherapeutische Unterschätzung der Tumorausdehnung. 32.5% (327/1007) mit gesicherten axillären Metastasen, in 26.3% (86/327) ≥ 4 LN+. Medianes Alter 56 (23–92) Jahre.

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Brual, Janette, Cherry Chu, Jiming Fang, et al. "Virtual care use among older immigrant adults in Ontario, Canada during the COVID-19 pandemic: A repeated cross-sectional analysis." PLOS Digital Health 2, no. 8 (2023): e0000092. http://dx.doi.org/10.1371/journal.pdig.0000092.

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The critical role of virtual care during the COVID-19 pandemic has raised concerns about the widening disparities to access by vulnerable populations including older immigrants. This paper aims to describe virtual care use in older immigrant populations residing in Ontario, Canada. In this population-based, repeated cross-sectional study, we used linked administrative data to describe virtual care and healthcare utilization among immigrants aged 65 years and older before and during the COVID-19 pandemic. Visits were identified weekly from January 2018 to March 2021 among various older adult im

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da Silva, Natascha, Matthias Hornung, Lukas Beyer, et al. "Intraoperative Shear Wave Elastography vs. Contrast-Enhanced Ultrasound for the Characterization and Differentiation of Focal Liver Lesions to Optimize Liver Tumor Surgery." Ultraschall in der Medizin - European Journal of Ultrasound 40, no. 02 (2018): 205–11. http://dx.doi.org/10.1055/a-0649-1000.

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Abstract Purpose Assessment of intraoperative quantitative shear wave elastography (SWE) and contrast-enhanced ultrasound (CEUS) for the characterization of focal liver lesions (FLLs) during liver surgery using postoperative histopathological results as the gold standard. Materials and Methods US data of 79 consecutive patients with 98 FLLs who underwent liver surgery between 08/2015 – 06/2017 were prospectively acquired and retrospectively analyzed. Multifrequency linear/T-shaped probes (6 – 9 MHz) were used to store cine loops of at least 5 s and images of B-mode, SWE and CEUS. The first CEU

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Celoto, M. I. B., M. F. S. Papa, L. V. S. Sacramento, and F. J. Celoto. "Atividade antifúngica de extratos de Momordica charantia L. sobre Colletotrichum musae." Revista Brasileira de Plantas Medicinais 13, no. 3 (2011): 337–41. http://dx.doi.org/10.1590/s1516-05722011000300013.

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Os objetivos do presente trabalho foram avaliar os efeitos de extratos de Momordica charantia sobre o crescimento micelial e a germinação de conídios de Colletotrichum musae, e a eficiência destes extratos no controle da antracnose, causada por C. musae, em bananas. Extratos aquoso e hidroetanólico, obtidos de folhas e ramos, na concentração de 50% em relação ao volume adicionado, em meio sólido, proporcionaram 71 e 65% de inibição do crescimento micelial, respectivamente, enquanto que em meio líquido, a inibição do crescimento micelial foi de 86 e 81%, respectivamente. Somente o extrato aquos

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Rainey, Carlisle, and Kelly McCaskey. "Estimating logit models with small samples." Political Science Research and Methods 9, no. 3 (2021): 549–64. http://dx.doi.org/10.1017/psrm.2021.9.

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AbstractIn small samples, maximum likelihood (ML) estimates of logit model coefficients have substantial bias away from zero. As a solution, we remind political scientists of Firth's (1993, Biometrika, 80, 27–38) penalized maximum likelihood (PML) estimator. Prior research has described and used PML, especially in the context of separation, but its small sample properties remain under-appreciated. The PML estimator eliminates most of the bias and, perhaps more importantly, greatly reduces the variance of the usual ML estimator. Thus, researchers do not face a bias-variance tradeoff when choosi

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Subedi, Ishwar, Christina Harnisch, Gerhard Kater, and Tulashi Adhikari. "Millet (Eleusine coracana) Flour Fortification in Composite Bread." Journal of Food Science and Technology Nepal 7 (June 16, 2014): 86–89. http://dx.doi.org/10.3126/jfstn.v7i0.10614.

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Composite bread prepared by wheat our (550 types, moisture 10.85%) and millet (Eleusine coracana) flour (moisture 10.8%) were determined to evaluate bread qualities by 2 methods. The first method included application of raw millet flour, where as the second methods included cooked (gelatinized) millet flour before baking. The breads were named as (0MB) only from wheat flour followed by (10CCMB), (20CCMB) and (30CCMB) using 10, 20 and 30 % coarse (669µm) cooked millet flour respectively where as (10FCMB) and (10FUMB) were named as fine (431µm) sized millet flour. The former was gelatinized wher

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Oluwayemi, Margaret Adefiola. "Prevalence of Diabetes and Knowledge of Risk Factors Among Patients’ Relatives in Ekiti State University Teaching Hospital, (EKSUTH), Ado-Ekiti, Ekiti State, Nigeria." International Journal of Dentistry, Diabetes, Endocrinology and Oral Hygiene 6, no. 1 (2024): 1–7. http://dx.doi.org/10.37745/ijddeoh.18/vol6n117.

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This study investigated prevalence of diabetes and knowledge of risk factors among relatives of diabetic patients in Ekiti State University Teaching Hospital (EKSUTH), Ado-Ekiti, Nigeria. After receiving Ethical approval and informed consent, structured questionnaire was administered to relatives of diabetic patients in male medical ward of the hospital. Measurement of fasting blood glucose (FBG) was also done following standard procedures. Descriptive and inferential statistics were used for data analysis. 13 (10.8%) had FBG at diabetes level. 7.8-12.1mg/dl. On knowledge of diabetes risk fact

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Marpid, Nuravifah Novembriana, Yogiek Indra Kurniawan, and Swahesti Puspita Rahayu. "ANALYSIS OF THE MOVIE DATABASE FILM RATING PREDICTION WITH ENSEMBLE LEARNING USING RANDOM FOREST REGRESSION METHOD." Jurnal Teknik Informatika (Jutif) 6, no. 1 (2025): 1–10. https://doi.org/10.52436/1.jutif.2025.6.1.1563.

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The film industry has become a very profitable industry. However, during COVID-19 the film industry experienced an unfavorable impact with the delay in the screening schedule of new films, many cinemas were prohibited from operating so they were completely closed, and it wasn’t easy to obtain permits to carry out the filmmaking process. To survive in this industry from the impact of the pandemic, it is necessary to consider several factors such as targeted promotion methods by using the right selection of predictive decisions with market and trends. Predicting the success of a film is very hel

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Morozov, Iurii, and Pavel Penkov. "Studying the possibilities of improving centrifugal separation efficiency." Izvestiya vysshikh uchebnykh zavedenii Gornyi zhurnal, no. 3 (May 14, 2020): 80–86. http://dx.doi.org/10.21440/0536-1028-2020-3-80-86.

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Object and aim of research. One direction in improving valuable components extraction in centrifugal separation is to apply it in the scheme of circular concentration. By means of multiple passing of a pulp flow through the centrifugal separator, higher indicators of valuable component extraction in heavy residue are ensured. The aim of this research is to study the possibility of improving the efficiency of centrifugal separation based on float circulation. Methodology. Laboratory testing has been carried out to cope with the given task. Centrifugal separation has been fulfilled in a laborato

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Turhan, Semin, Duygu Tutan, Yeliz Şahiner, et al. "Predictive Value of Serial Rapid Shallow Breathing Index Measurements for Extubation Success in Intensive Care Unit Patients." Medicina 60, no. 8 (2024): 1329. http://dx.doi.org/10.3390/medicina60081329.

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Background and Objectives: Extubation success in ICU patients is crucial for reducing ventilator-associated complications, morbidity, and mortality. The Rapid Shallow Breathing Index (RSBI) is a widely used predictor for weaning from mechanical ventilation. This study aims to determine the predictive value of serial RSBI measurements on extubation success in ICU patients on mechanical ventilation. Materials and Methods: This prospective observational study was conducted on 86 ICU patients at Hitit University between February 2024 and July 2024. Patients were divided into successful and unsucce

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Yorio, Jeffrey Thomas, Patricia S. Fox, Richard Wayne Joseph, Roland Bassett, and Michael A. Davies. "Assessment of absolute lymphocyte count (ALC) as a predictor of progression-free survival (PFS) and overall response rate (ORR) in metastatic melanoma (MM) patients (pts) treated with high-dose interleukin-2 (HD IL-2)." Journal of Clinical Oncology 31, no. 15_suppl (2013): 9096. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.9096.

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9096 Background: HD IL-2 is an approved immunotherapy that can achieve durable cures in MM pts. Due to toxicity and low ORR, identification of predictors of clinical benefit would enhance pt selection and outcomes with HD IL-2. Recent research identified a positive correlation for ALC ≥ 1000 (either at baseline or at dose 3) with OS among MM pts treated with the immunotherapy agent ipilimumab. We tested the hypothesis that ALC (≥ 1000) or other hematological parameters correlates with clinical benefit from HD IL2. Methods: Results of hematologic testing in patients (n=98) treated with HD IL2 a

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Wang, Yafei, Fan Yang, and Fanneng He. "Reconstruction of Forest and Grassland Cover for the Conterminous United States from 1000 AD to 2000 AD." Remote Sensing 15, no. 13 (2023): 3363. http://dx.doi.org/10.3390/rs15133363.

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Spatially explicit reconstruction of historical land cover change is a prerequisite for a more comprehensive understanding of environmental changes. Anthropogenic activities have dramatically altered the land cover of the conterminous United States (CONUS), encroaching heavily on the primary vegetation. However, few datasets exist that depict the historical trajectory of forest and grassland cover changes in CONUS over the last millennium, and previous efforts have only focused on reconstructions for the last four centuries. By integrating remote sensing-derived land use/cover change (LUCC) da

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Larson, Richard A., Brian J. Druker, Francois Guilhot, et al. "Correlation of Pharmacokinetic Data with Cytogenetic and Molecular Response in Newly Diagnosed Patients with Chronic Myeloid Leukemia in Chronic Phase (CML-CP) Treated with Imatinib - An Analysis of IRIS Study Data." Blood 108, no. 11 (2006): 429. http://dx.doi.org/10.1182/blood.v108.11.429.429.

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Abstract A total of 551 pts with newly diagnosed CML-CP received imatinib (IM) 400 mg orally once daily as part of the IRIS study (O’Brien et al, NEJM 2003). We now summarize the correlation of clinical responses with the steady-state trough plasma concentrations (Cmin) of IM and its major active metabolite CGP74588. Cmin is a reflection of IM clearance and metabolism in CML pts. Trough PK samples (24 hrs post dose) were obtained in IM pts at Day 1 and steady state (Day 29). The plasma concentrations of IM and CGP74588 were determined by liquid chromatography/mass spectrometry. Estimated rates

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Martínez-Baz, Iván, Camino Trobajo-Sanmartín, Ana Miqueleiz, et al. "Hospitalisations and Deaths Averted by COVID-19 Vaccination in Navarre, Spain, 2021–2022." Vaccines 12, no. 1 (2024): 58. http://dx.doi.org/10.3390/vaccines12010058.

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In 2021-2022, most of the Spanish population received COVID-19 vaccines and a high proportion of them had SARS-CoV-2 infection. We estimated the rate of hospitalisations and deaths that were averted by risk reduction among vaccinated COVID-19 cases. Hospitalisations and deaths were analysed among COVID-19 cases confirmed in 2021 and 2022 in Navarre, Spain. To calculate the number of prevented outcomes by sex, age, comorbidities, and semester, the difference in the risk of each outcome between unvaccinated and vaccinated cases was multiplied by the number of vaccinated cases. COVID-19 vaccinati

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Nasir, Irfan, Husnain Haider, Md Shafiquzzaman, Majed Alinizzi, Guangji Hu, and Abdul Razzaq Ghumman. "Investigating the Effects of Occupancy and Natural Ventilation on the Indoor Air Quality of Dormitories in Cold Regions." Buildings 15, no. 6 (2025): 896. https://doi.org/10.3390/buildings15060896.

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Indoor air quality (IAQ) in higher education institutions’ dormitories, without mechanical ventilation, is a significant concern for students’ health due to prolonged occupancy in cold regions. The present investigation assessed IAQ by measuring two dormitories’ CO2, temperature, and relative humidity with the presence of one, two, three, and four occupants in the United Kingdom. Considering the possibility of natural ventilation by opening the windows in the summer, IAQ was monitored using two sensors located at 1 m and 2 m heights from the floor level of the dormitories in July. The tracer m

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Su, Jun, Zongyang Li, Longlong Hao, and Lilu Qin. "Preparation and Electrocatalytic Activity of a Cobalt Mixed Nitrogen 3D Carbon Nanostructure @ Carbon Felt toward an All-Vanadium Redox Flow Battery." Applied Sciences 12, no. 5 (2022): 2304. http://dx.doi.org/10.3390/app12052304.

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All-vanadium redox flow batteries (VRFBs), with good operation flexibility and scalability, have been regarded as one of the most competitive substitutes for large-scale energy storage. However, because of the low electrochemical activities of traditional electrodes such as carbon felt and graphite felt, they will impede the interfacial charge transfer processes and decrease the efficiencies of VRFBs. In this work, Co-MOF (ZIF-67) was prepared as a precursor, and a cobalt mixed nitrogen 3D carbon nanostructure and carbon felt (Co-CN@CF) was prepared by chemical reaction and used in VRFBs as el

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Alshamrani, Abdullah Fahad A. "Diagnostic Accuracy of Molecular Imaging Techniques for Detecting Prostate Cancer." Diagnostics 14, no. 13 (2024): 1315. http://dx.doi.org/10.3390/diagnostics14131315.

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Molecular imaging modalities show valuable non-invasive techniques capable of precisely and selectively addressing molecular markers associated with prostate cancer (PCa). This systematic review provides an overview of imaging markers utilized in positron emission tomography (PET) methods, specifically focusing on the pathways and mediators involved in PCa. This systematic review aims to evaluate and analyse existing literature on the diagnostic accuracy of molecular imaging techniques for detecting PCa. The PubMed, EBSCO, ScienceDirect, and Web of Science databases were searched, identifying

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Menegaes, Janine Farias, Alexandre Swarowsky, Fernanda Alice Antonello Londero Backes, Rogério Antonio Bellé, and Hélcio José Izário Filho. "CONSUMO HÍDRICO DE CALLA LILY SUBMETIDA AO MANEJO DE IRRIGAÇÃO VIA SOLO E TEORES DE COBRE1." IRRIGA 22, no. 1 (2017): 74–86. http://dx.doi.org/10.15809/irriga.2017v22n1p74-86.

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CONSUMO HÍDRICO DE CALLA LILY SUBMETIDA AO MANEJO DE IRRIGAÇÃO VIA SOLO E TEORES DE COBRE1 JANINE FARIAS MENEGAES2; ALEXANDRE SWAROWSKY3; FERNANDA ALICE ANTONELLO LONDERO BACKES4; ROGÉRIO ANTONIO BELLÉ4 E HÉLCIO JOSÉ IZÁRIO FILHO5 1 Manuscrito referente a parte da Dissertação de Mestrado em Engenharia Agrícola de Janine Farias Menegaes.2 Eng. Agrônoma, Mestranda do Programa de Pós-Graduação em Engenharia Agrícola (PPGEA), Universidade Federal de Santa Maria (UFSM), Avenida Roraima, 1000, Prédio 42, Sala 3325, CEP 97.105-900, Santa Maria, RS, Brasil. janine_rs@hotmail.com3 Doutor, Professor do

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Ламмас, М. Е., А. А. Коршунов, and А. С. Пономарёва. "The impact of gibberellic acid sodium salts on the growth rate, productivity and grain quality of spring barley." Кормопроизводство, no. 8.2023 (November 25, 2023): 10–13. http://dx.doi.org/10.25685/krm.2023.8.2023.001.

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В условиях Рязанской области в 2020–2022 годах проводили исследования, в задачи которых входило изучение влияния обработок препаратом «Гиберелон, ВРП» (концентрация натриевых солей гиббереллиновых кислот — 40 г/кг) на темпы роста, урожайность и качество зерна ярового ячменя сорта Московский 3. Наши исследования показали равномерное улучшение показателей структуры урожая. Высота растений ярового ячменя в вариантах с обработкой регулятором роста была более выровненной, однородной и составила 85–86 см (+2,4–3,6% к контролю). Длина колоса достигала в вариантах с обработкой «Гиберелоном» 8,7–8,8 см

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Ponazhev, V. P. "INCREASE OF SELECTION EFFICIENCY OF FLAX INITIAL MATERIAL IN PRIMARY SEED PRODUCTION." Vestnik of Ulyanovsk state agricultural academy 204, no. 2(58) (2022): 80–86. http://dx.doi.org/10.18286/1816-4501-2022-2-80-86.

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The studies were carried out on the basis of the laboratory of breeding technologies of the Federal State Budgetary Scientific Institution "Federal Scientific Center of Bast Crops" (Tver region) in 2019-2021. The purpose of the research is to study selection effectiveness of fiber flax plants for a new trait - height at various seeding amounts in the selection nursery. It was established that initial testing with subsequent removal of plants that were not included in the interval of typical height (± 10% of the average value) allowed to ensure a higher uniformity of typical plants in terms of

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Wati, Sinta, and Mateus Sakundarno Adi. "Gambaran Kematian Neonatal Berdasarkan Karakteristik Ibu di Kota Semarang." Jurnal Epidemiologi Kesehatan Komunitas 5, no. 2 (2020): 82–87. http://dx.doi.org/10.14710/jekk.v5i2.6430.

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Background: The Neonatal Mortality Rate of Central Java in 2018 was 7.3 per 1000 live births and the neonatal mortality rate in Semarang City in 2018 was 4.57 per 1000 live births. The purpose of this study was to analyze neoanatal mortality based on maternal characteristics in Semarang City.Methods: This research used descriptive analysis, derived from secondary data in the Semarang City Health Office. The data was taken from Verbal Perinatal Autopsy data sampling from neonatal cases aged 0-28 days who died in Semarang City. In 2019 there were 50 cases out of 101 neonatal death cases.Results:

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Zhao, Grace Q., Yun Bao, Heng Wang, Jianmin Wang, and Shengrong Lin. "The development and validation of a novel targeted methylation sequencing technology detecting 0.003 percent tumor signal in early-stage cancer plasma." Journal of Clinical Oncology 38, no. 15_suppl (2020): 4092. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.4092.

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4092 Background: Methylation analysis in cell-free DNA holds great potential for early cancer detection. In the plasma of early stage cancer patient, the tumor content is estimated to be less than 0.1%, therefore demands a highly sensitive assay. Targeted Methylation Sequencing (TMS) is the most promising approach; however, the current sensitivity and specificity are compromised by low efficiency and low recovery of target enrichment, and further hampered by background noise associated with large panels. The ideal solution would be an in-depth analysis using a focused small cancer-specific met

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El-Khoueiry, Anthony B., Richard D. Kim, William Proctor Harris, et al. "Updated results of a phase 1b study of regorafenib (REG) 80 mg/day or 120 mg/day plus pembrolizumab (PEMBRO) for first-line treatment of advanced hepatocellular carcinoma (HCC)." Journal of Clinical Oncology 39, no. 15_suppl (2021): 4078. http://dx.doi.org/10.1200/jco.2021.39.15_suppl.4078.

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4078 Background: REG, a multikinase inhibitor, and PEMBRO, an anti-PD-1 mAb, are approved as monotherapies in advanced HCC after progression on sorafenib. This phase 1b dose-finding study investigated first-line REG plus PEMBRO in advanced HCC. Methods: Patients (pts) in the first cohort received a starting REG dose of 120 mg/day orally for 3 weeks (wks) on/1 wk off, which could be escalated (160 mg) or reduced (80 mg) in later cohorts, plus a fixed dose of PEMBRO 200 mg IV every 3 wks. Due to a high dose modification rate in the REG 120 mg cohort, an exploratory REG 80 mg cohort was introduce

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Gupta, Mihir, Evan J. Burns, Nicholas Z. Georgantas, et al. "A rapid genotyping panel for detection of primary central nervous system lymphoma." Blood 138, no. 5 (2021): 382–86. http://dx.doi.org/10.1182/blood.2020010137.

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Abstract Diagnosing primary central nervous system lymphoma (PCNSL) frequently requires neurosurgical biopsy due to nonspecific radiologic features and the low yield of cerebrospinal fluid (CSF) studies. We characterized the clinical evaluation of suspected PCNSL (N = 1007 patients) and designed a rapid multiplexed genotyping assay for MYD88, TERT promoter, IDH1/2, H3F3A, and BRAF mutations to facilitate the diagnosis of PCNSL from CSF and detect other neoplasms in the differential diagnosis. Among 159 patients with confirmed PCNSL, the median time to secure a diagnosis of PCNSL was 10 days, w

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Martinez-Alanis, Marisol, Erik Bojorges-Valdez, Niels Wessel, and Claudia Lerma. "Prediction of Sudden Cardiac Death Risk with a Support Vector Machine Based on Heart Rate Variability and Heartprint Indices." Sensors 20, no. 19 (2020): 5483. http://dx.doi.org/10.3390/s20195483.

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Most methods for sudden cardiac death (SCD) prediction require long-term (24 h) electrocardiogram recordings to measure heart rate variability (HRV) indices or premature ventricular complex indices (with the heartprint method). This work aimed to identify the best combinations of HRV and heartprint indices for predicting SCD based on short-term recordings (1000 heartbeats) through a support vector machine (SVM). Eleven HRV indices and five heartprint indices were measured in 135 pairs of recordings (one before an SCD episode and another without SCD as control). SVMs (defined with a radial basi

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Grosembacher, Luis, Roxana Groppa, Javier Giunta, et al. "O20 Trasplante de páncreas aislado en pacientes con diabetes mellitus tipo 1. Resultados metabólicos luego de cinco años de experiencia." Revista de la Sociedad Argentina de Diabetes 54, no. 3Sup (2020): 105. http://dx.doi.org/10.47196/diab.v54i3sup.381.

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Introducción: el trasplante de páncreas aislado (PTA) restaura el control glucémico con independencia a la insulina exógena en el postrasplante (posTx) en pacientes con diabetes mellitus tipo 1 (DM1). Del 8 al 10% de los trasplantes de páncreas son PTA. Avances en técnicas quirúrgicas e inmunosupresión mejoraron resultados del PTA. Según el Registro Internacional de Trasplante, aumentó la supervivencia a 5 años, del paciente y del injerto pancreático 86 y 60% respectivamente.Objetivos: evaluar los resultados metabólicos del PTA, en pacientes con DM1, del programa institucional de Trasplantes d

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Aakjær, Mia, Morten Houlind, Charlotte Treldal, et al. "Differences in Kidney Function Estimates Based on Creatinine and/or Cystatin C in Non-Traumatic Amputation Patients and Their Impact on Drug Prescribing." Journal of Clinical Medicine 8, no. 1 (2019): 89. http://dx.doi.org/10.3390/jcm8010089.

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Accurate kidney function estimates are necessary when prescribing renally-eliminated medications. Our objectives were to investigate how amputation affects estimated glomerular filtration rate (eGFR) and to determine if dosing recommendations differ among different eGFR equations. In a cohort study of non-traumatic amputation patients, eGFR based on creatinine and/or cystatin C were measured before and after amputation. Prescribed, renally-eliminated medications were compared with dosing guidelines in Renbase®. Data from 38 patients with a median age of 75 years were analyzed. The median (rang

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Bhatta, Santosh, Dan Magnus, Julie Mytton, et al. "The Epidemiology of Injuries in Adults in Nepal: Findings from a Hospital-Based Injury Surveillance Study." International Journal of Environmental Research and Public Health 18, no. 23 (2021): 12701. http://dx.doi.org/10.3390/ijerph182312701.

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This study aimed to develop and evaluate a model of hospital-based injury surveillance and describe the epidemiology of injuries in adults. One-year prospective surveillance was conducted in two hospitals in Hetauda, Nepal. Data were collected electronically for patients presenting to emergency departments (EDs) with injuries between April 2019 and March 2020. To evaluate the model’s sustainability, clinical leaders, senior managers, data collectors, and study coordinators were interviewed. The total number of patients with injuries over one year was 10,154, representing 30.7% of all patients

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Mate Landry, Gilgen, Rodolphe Nsimba Malumba, Fiston Chrisnovi Balanganayi Kabutakapua, and Bopatriciat Boluma Mangata. "PERFORMANCE COMPARISON OF CLASSICAL ALGORITHMS AND DEEP NEURAL NETWORKS FOR TUBERCULOSIS PREDICTION." Jurnal Techno Nusa Mandiri 21, no. 2 (2024): 126–33. http://dx.doi.org/10.33480/techno.v21i2.5609.

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This study compares the performance of several classical machine learning algorithms and deep neural networks for the prediction of tuberculosis in the Democratic Republic of Congo (DRC), using a sample of 1000 cases including clinical and demographic data. The sample is divided into two sets: 80% for training and 20% for testing. The algorithms evaluated include Support Vector Machine (SVM), K-Nearest Neighbors (KNN), Decision Tree, Random Forest and Convolutional Neural Networks (CNN). The results show that the CNN has the best overall performance with an accuracy of 94%, an AUC of the ROC c

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Mariani, Ilaria, Cesare Maino, Teresa Paola Giandola, et al. "Texture Analysis and Prediction of Response to Neoadjuvant Treatment in Patients with Locally Advanced Rectal Cancer." Gastrointestinal Disorders 6, no. 4 (2024): 858–70. http://dx.doi.org/10.3390/gidisord6040060.

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Background: The purpose of this study is to determine the relationship between the texture analysis extracted from preoperative rectal magnetic resonance (MR) studies and the response to neoadjuvant treatment. Materials and Methods: In total, 88 patients with rectal adenocarcinoma who underwent staging MR between 2017 and 2022 were retrospectively enrolled. After the completion of neoadjuvant treatment, they underwent surgical resection. The tumour regression grade (TRG) was collected. Patients with TRG 1–2 were classified as responders, while patients with TRG 3 to 5 were classified as non-re

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Monika, Kumar Ram Manoj, and Singh Alka. "A Cross-Sectional Study to Examine the Factors That Influence Breastfeeding Initiation in Women with Infants Younger Than One Year of Age." International Journal of Current Pharmaceutical Review and Research 16, no. 02 (2024): 232–38. https://doi.org/10.5281/zenodo.11353861.

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Aim: The aim of the present study was to assess timely initiation of breastfeeding and associated factors amongmothers of children less than 12 months old.Methods: The present study was conducted at department of Pediatrics, NMCH, Patna, Bihar, India andmothers who have a child less than 12 months of age were included in the study. Total 1000 mothers wereincluded in the study.Results: In this study, 500 mothers had infants less than 12 months participated in this study making theresponse rate 98%. The mean age of mothers that participated in this study was 24.96 with the standarddeviation of (

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Smith, Sinéad M., Olga P. Nyssen, Rebecca FitzGerald, et al. "First-Line Prescriptions and Effectiveness of Helicobacter pylori Eradication Treatment in Ireland over a 10-Year Period: Data from the European Registry on Helicobacter pylori Management (Hp-EuReg)." Antibiotics 14, no. 7 (2025): 680. https://doi.org/10.3390/antibiotics14070680.

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Background: Local audits of Helicobacter pylori (H. pylori) prescriptions and outcomes are necessary to assess guideline awareness among clinicians and treatment effectiveness. Aims: The aims were to investigate first-line prescriptions and effectiveness over a 10-year period in Ireland and evaluate the influence of the 2017 Irish consensus guidelines on these trends. Methods: Data were collected at e-CRF AEG-REDCap from the European Registry on H. pylori management (Hp-EuReg) and quality reviewed from 2013 to 2022. All treatment-naïve cases were assessed for effectiveness by modified intentio

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Núñez-Samudio, Virginia, Aris Jiménez-Domínguez, Humberto López Castillo, and Iván Landires. "Epidemiologic Characteristics of Suicide in Panama, 2007–2016." Medicina 56, no. 9 (2020): 442. http://dx.doi.org/10.3390/medicina56090442.

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Background and objectives: We aim to describe the demographic characteristics associated with suicide in Panama, to estimate the suicide mortality rate and years of potential life lost (YPLL) to suicide, and to explore the correlation of suicide rates with the Multidimensional Poverty Index (MPI). We present a descriptive retrospective epidemiological report of suicide-related mortality (Panama, 2007–2016). Materials and Methods: Data were matched-merged to calculate unadjusted suicide mortality rates (overall, and by sex, age groups, and administrative region), YPLL, and coefficients (r) for

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Heller, P. R., and S. Kellogg. "Hairy Chinch Bug Control on a Home Lawn in Butler, Pa., 1987." Insecticide and Acaricide Tests 13, no. 1 (1988): 353. http://dx.doi.org/10.1093/iat/13.1.353.

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Abstract The lawn consisted primarily of fine leafed fescue. Treatment plots were 5 × 6 ft, arranged in a randomized complete block design and replicated 3 times. Liquid formulations were applied by using a COa sprayer with four 8004VS Teejet nozzles mounted on a 6-ft boom, operating at 28 psi, and delivering 5 gal/1000 sq ft. Granular formulations were applied with a handheld shaker and mixed with a fine grade of top-dressing sand to facilitate product distribution. At treatment time, the following soil and environmental conditions existed: air temperature, 86°F; soil temperature, 90°F; RH, 8

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Bandan., Sheikh Sadi, MD Samiul Islam Sabbir., Md Sharuf Hossain., and Khadiza Tul Kobra. "Enhancing Fashion Choices: AI-Powered Style Analysis and Recommendations." International Journal of Research and Innovation in Applied Science IX, no. VIII (2024): 478–90. http://dx.doi.org/10.51584/ijrias.2024.908042.

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Fashion has always been an essential feature of our daily routine. It plays an important role in everyone’s life. The online fashion market continues to grow, and an algorithm capable of identifying clothing can help companies in the apparel industry understand the profile of potential buyers and focus sales on specific niches. Artificial intelligence capable of understanding, recommending and labeling human clothing is essential, and can be used to improve sales or better understand users. In this paper, we used our own generated dataset, where the total number of data was 1000. The dataset c

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Shyam, Bahadur Prasad, Kumar Sahu Amresh, and Kumar Anil. "Determining the Various Factors in Timely Initiation of Breastfeeding among Mothers of Children." International Journal of Current Pharmaceutical Review and Research 16, no. 4 (2024): 327–33. https://doi.org/10.5281/zenodo.12788820.

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Aim: The aim of the present study was to assess timely initiation of breastfeeding and associated factors amongmothers of children less than 12 months old.Methods: The present study was conducted department of pediatrics, Government Medical College Bettiah, WestChamparan, Bihar, India and mothers who have a child less than 12 months of age were included in the study.Total 1000 mothers were included in the study.Results: In this study, 500 mothers had infants less than 12 months participated in this study making the responserate 98%. The mean age of mothers that participated in this study was 2

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Fairey, N. A., and L. P. Lefkovitch. "Crop density and seed production of tall fescue (Festuca arundinacea Schreber). 2. Reproductive components and seed characteristics." Canadian Journal of Plant Science 79, no. 4 (1999): 543–49. http://dx.doi.org/10.4141/p98-113.

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The population density and spatial arrangement of plants may influence the productive life and performance characteristics of a perennial grass-seed crop. A study was conducted to determine the effects of the initial density (1.6, 3.1, 6.3, 12.5, 25, 50 and 100 plants m−2) and row spacing (20, 40, and 80 cm) of plants on reproductive yield components and seed characteristics of tall fescue (Festuca arundinacea Schreber), over 3 consecutive production years (1991–1993) in the Peace region of Canada. The weight proportion of cleaned-to-uncleaned seed was 85–86% for the three lowest plant densiti

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Ando, Tomo, Oluwole Adegbala, Takeshi Uemura, et al. "Incidence, Trends, and Predictors of Palliative Care Consultation After Aortic Valve Replacement in the United States." Journal of Palliative Care 34, no. 2 (2018): 111–17. http://dx.doi.org/10.1177/0825859718819433.

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Aim: Transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) have become a reasonably safe procedure with acceptable morbidity and mortality rate. However, little is known regarding the incidence, trends, and predictors of palliative care (PC) consult in aortic valve replacement (AVR) patients. The main purpose of this analysis was to assess the incidence, trends, and predictors of PC consultation in AVR recipients using the Nationwide Inpatient Sample (NIS) database. Materials and Methods: We queried the NIS database from 2005 to September 2015 to identify t

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Semrau, Katherine EA, Kate A. Miller, Stuart Lipsitz, et al. "Does adherence to evidence-based practices during childbirth prevent perinatal mortality? A post-hoc analysis of 3,274 births in Uttar Pradesh, India." BMJ Global Health 5, no. 9 (2020): e002268. http://dx.doi.org/10.1136/bmjgh-2019-002268.

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BackgroundEvidence-based practices that reduce childbirth-related morbidity and mortality are core processes to quality of care. In the BetterBirth trial, a matched-pair, cluster-randomised controlled trial of a coaching-based implementation of the WHO Safe Childbirth Checklist (SCC) in Uttar Pradesh, India, we observed a significant increase in adherence to practices, but no reduction in perinatal mortality.MethodsWithin the BetterBirth trial, we observed birth attendants in a subset of study sites providing care to labouring women to assess the adherence to individual and groups of practices

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Dilrukshi, W. M. D., N. Dahanayake, A. S. Balasooriya, and U. Priyadarshana. "Analyze the Seed Quality of <em>Capsicum annum</em> (Clv. GROSSUM) by Maintaining an Optimum Number of Fruits Load in the Plant." Tropical Agricultural Research and Extension 27, no. 1 (2024): 49–53. http://dx.doi.org/10.4038/tare.v27i1.5672.

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Capsicum annum, commonly known as bell pepper, belongs to the Solanaceae family, specifically the Grossum Group. Various cultivars of this plant yield fruits in diverse colors, such as red, yellow, orange, green, white, and purple. The quality of Capsicum annum seeds is closely tied to the quantity of fruits produced. It was observed that as the number of fruits per plant increases, the seed quality tends to decrease. The primary objective of this study was to examine the relationship between seed quality and the number of fruits per plant. Awareness of the optimal fruit yield achievable with

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Agung, Mochamad Untung Kurnia, and Maelita Ramdani Moeis. "Transposon Insertion Phenomenon during Cloning of a Partial Fragment Derived from Metagenomic DNA Isolated from Deep-Sea Water and Sediment of Kawio Island, North Sulawesi." Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology 8, no. 3 (2013): 129. http://dx.doi.org/10.15578/squalen.v8i3.84.

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Transposon is well-known as mobile element found abundant both in prokaryote and eukaryote genomes. In bacteria, transposon (famous name of a transposable DNA) could jump from chromosome to plasmid and its contrary. One type of transposons in bacteria known as insertion sequence (IS), it does not contain any additional genes except a gene encoding transposase, an enzyme that correlated to transponsition activities. The finding of transposon insertion unfortunately found during cloning of a fragment derived from deep-sea metagenomic DNA in this research. In the initial, this research was aimed

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Matsubara, Toshiyuki, Takashi Ohshiro, Yoshihiro Nishina, and Yoshikazu Izumi. "Purification, Characterization, and Overexpression of Flavin Reductase Involved in Dibenzothiophene Desulfurization byRhodococcus erythropolis D-1." Applied and Environmental Microbiology 67, no. 3 (2001): 1179–84. http://dx.doi.org/10.1128/aem.67.3.1179-1184.

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ABSTRACT The dibenzothiophene (DBT)-desulfurizing bacterium,Rhodococcus erythropolis D-1, removes sulfur from DBT to form 2-hydroxybiphenyl using four enzymes, DszC, DszA, DszB, and flavin reductase. In this study, we purified and characterized the flavin reductase from R. erythropolis D-1 grown in a medium containing DBT as the sole source of sulfur. It is conceivable that the enzyme is essential for two monooxygenase (DszC and DszA) reactions in vivo. The purified flavin reductase contains no chromogenic cofactors and was found to have a molecular mass of 86 kDa and four identical 22-kDa sub

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Panousis, Nikolaos I., George K. Bertsias, Halit Ongen, et al. "Combined genetic and transcriptome analysis of patients with SLE: distinct, targetable signatures for susceptibility and severity." Annals of the Rheumatic Diseases 78, no. 8 (2019): 1079–89. http://dx.doi.org/10.1136/annrheumdis-2018-214379.

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ObjectivesSystemic lupus erythematosus (SLE) diagnosis and treatment remain empirical and the molecular basis for its heterogeneity elusive. We explored the genomic basis for disease susceptibility and severity.MethodsmRNA sequencing and genotyping in blood from 142 patients with SLE and 58 healthy volunteers. Abundances of cell types were assessed by CIBERSORT and cell-specific effects by interaction terms in linear models. Differentially expressed genes (DEGs) were used to train classifiers (linear discriminant analysis) of SLE versus healthy individuals in 80% of the dataset and were valida

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