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Journal articles on the topic '914.19/6/0380924 b'

Author: Grafiati

Published: 26 July 2024

Last updated: 31 July 2025

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1

Taher, Ali, Amal El-Beshlawy, Abdullah Al Jefri та ін. "Deferasirox (Exjade®, ICL670) Treatment of Inadequately Chelated β-Thalassemia Patients from the Middle East: The ESCALATOR Trial." Blood 106, № 11 (2005): 3840. http://dx.doi.org/10.1182/blood.v106.11.3840.3840.

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Abstract Iron overload is a potentially life-threatening consequence of multiple blood transfusions. Effective iron chelation therapy reduces morbidity and saves lives. Many patients are unable to comply with current treatments, deferoxamine (DFO) or deferiprone (L1), because they cannot tolerate the parenteral infusion regimen required for DFO, because of adverse events (AEs), or because they do not respond to treatment. The objective of the ESCALATOR trial is to evaluate the effectiveness of deferasirox, an investigational once-daily oral iron chelator in advanced clinical development, in re

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Jullien, Maxime, Amandine Le Bourgeois, Marianne Coste-Burel, et al. "Profound B-Cell Lymphopenia Is a Major Factor Predicting Poor Humoral Response after BNT162b2 mRNA Sars-Cov-2 Vaccines in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation." Blood 138, Supplement 1 (2021): 3911. http://dx.doi.org/10.1182/blood-2021-150439.

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Abstract Background Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection results in poor outcome in patients with hematologic malignancies. Moreover, the efficacy of anti-SARS-CoV-2 mRNA vaccines appears lower in immunocompromised patients, including recipients of allogeneic stem cell transplantation (Allo-HSCT). In this population, data are scarce regarding factors predicting the response to mRNA vaccines. Methods This retrospective study aimed to decipher which factors, including immune status at time of vaccine and recipient/donor blood groups, might influence the antibody

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Caivano, Antonella, Luciana De Luca, Ilaria Laurenzana, et al. "High Serum Levels of Extracellular Vesicles which Express Specific Markers of Malignancy Are Released in Patients with Various Types of Hematological Neoplastic Disorders." Blood 124, no. 21 (2014): 2917. http://dx.doi.org/10.1182/blood.v124.21.2917.2917.

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Abstract INTRODUCTION: Extracellular vesicles (EVs), including exosomes, shedding vesicles (microvesicles: MVs) and apoptotic bodies, are membrane vesicles of 40-3,000 nm that are released from many cell types, such as red blood cells, platelets, lymphocytes, dendritic cells, endothelial cells and tumour cells. They have a key role not only in the regulation of normal physiological processes, but also in the pathology underlying several diseases. Recently, it was discovered that EVs circulate in bodily fluids of cancer patients and could serve as potential diagnostic biomarkers. However, the p

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Tarella, Corrado, Angela Gueli, Federica Delaini, et al. "Primary Refractory Disease in Non-Hodgkin's Lymphoma: A Retrospective Study On 3,952 Newly Diagnosed Patients Undergoing First-Line Chemotherapy." Blood 120, no. 21 (2012): 305. http://dx.doi.org/10.1182/blood.v120.21.305.305.

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Abstract Abstract 305 Introduction: Non-Hodgkin's lymphoma (NHL) are malignant tumors usually sensitive to chemotherapy; this results in prolonged survival and possibly disease eradication in a large proportion of patients. However, despite the general improvement in treatment options, a variable number of patients still shows a refractory disease, i.e. poor or absent response to induction therapy. Prediction and management of refractory disease is a major issue in the biological and clinical research programs for NHL. The present study was undertaken to evaluate on a large series of NHL patie

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Kewan, Tariq, Sayeef Mirza, Alexander B. Pine, et al. "CAR T-Related Toxicities Based on Dynamic Proteomic Profiles Identifies Risk Factors for Cytokine Release Syndrome (CRS) and Immune Effector Cell -Associated Neurotoxicity Syndrome (ICANS)." Blood 142, Supplement 1 (2023): 2132. http://dx.doi.org/10.1182/blood-2023-187295.

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TK and SM are Co-first authors INTRODUCTION Treatment with chimeric antigen receptor (CAR) T-cells significantly improved outcomes in relapsed/refractory non-Hodgkin lymphoma (NHL) and multiple myeloma (MM). CAR-T activation and anti-tumor cytotoxicity are associated with bystander inflammatory reactions resulting in CRS and/or ICANS. Due to complex cytokine profiles, disease heterogeneity, and variability between commercial CAR-T products, identification of risk factors associated with CRS and/or ICANS has been challenging. In this study, we used plasma proteomic profiling at different timepo

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Гасанова, Гюнель Самир, Айтен Исмет Агазаде, Юсиф Амиралы Юсибов та Магомед Баба Бабанлы. "Термодинамическое исследование системы Bi2Se3–Bi2Te3 методом ЭДС". Kondensirovannye sredy i mezhfaznye granitsy = Condensed Matter and Interphases 22, № 3 (2020): 310–19. http://dx.doi.org/10.17308/kcmf.2020.22/2961.

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Бинарные и сложные халькогениды с тетрадимитоподобной слоистой структурой представляют большой практический интерес как топологические изоляторы, термоэлектрические и оптоэлектронные материалы. Их фундаментальные термодинамические функции в совокупности с фазовыми диаграммами важны для разработки и оптимизации методов синтеза и выращивания кристаллов. В работе представлены результаты термодинамического исследования исходных соединений и твердых растворов системы Bi2Se3-Bi2Te3 методом электродвижущих сил (ЭДС). Различные модификации этого метода широко применяются для исследования бинарных и сл

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Prado Matamoros, Andrea Michelle, Karla Gisella Velásquez Paccha, and Walter Adalberto González García. "TRATAMIENTO NUTRICIONAL DE LA DIABETES TIPO II Y LA OBESIDAD." Universidad Ciencia y Tecnología 24, no. 106 (2020): 109–18. http://dx.doi.org/10.47460/uct.v24i106.403.

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La obesidad y la diabetes mellitus tipo II (DMT2) han sido declaradas pandemias del nuevo siglo, en virtud de su acelerado crecimiento y presencia en la población mundial. Sin embargo, el enfoque empleado en los tratamientos de estas condiciones ha radicado en la atención farmacológica de las comorbilidades asociadas, sin conseguir efectos positivos en la enfermedad en el largo plazo. En tal sentido, la investigación tuvo como objetivo determinar los parámetros básicos de atención de la obesidad y la DMT2, a través de la atención nutricional no farmacológica mediante una revisión bibliográfica

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Hefdhallah, Al-Aizari, Achaouch Abdelaziz, Fadli Mohamed, Al-Mashreki Mohammed, and Al-Kadse Fouad. "Physico-Chemical Analysis of Selected Groundwater Samples in Dhamar basin area, Yemen." Biolife 5, no. 4 (2022): 493–504. https://doi.org/10.5281/zenodo.7392710.

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<strong>ABSTRACT</strong> In this paper, the study aims to analyze the physicochemical properties of water in the region of Dhamar (Yemen).          We have chosen five Qa's (sectors) from the Dhamar Basin (<em>Qa 'sherah, Qa' Samah Qa 'Balasan, Wadi Almawaheb, and Qa' Asawad</em>). The physicochemical parameters such as T<sup>o</sup>, pH, EC and TH and the major ions Na<sup>+</sup>, k<sup>+</sup> Ca<sup>2+</sup>, Mg<sup>2+</sup>, Cl<sup>-</sup>, SO<sub>4</sub><sup>2-</sup>, HCO<sub>3</sub><sup>-</sup> were evaluated in 60 wells:

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Araújo, Rhoberta Santana de, Fabíola Bouth Grello Kato, and Vera Lúcia Jacob Chaves. "O programa Future-se e o desmonte do financiamento público e da autonomia universitária (The Future-se program and the dismantlement of public financing and university autonomy)." Revista Eletrônica de Educação 14 (October 29, 2020): 4543137. http://dx.doi.org/10.14244/198271994543.

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The text analyses three versions of “Programa Universidades e Institutos Empreendedores e Inovadores - Future-se”, presented by the Brazilian federal government. The proposition has been targeted by intense criticism, triggering an ample process of mobiliation and rejection by the deliberative organs of the Higher education federal institutions. The methodological procedures were guided by bibliographical revision and documental analysis with a qualitative nature approach. In the analysis, it was identified that, beyond the privatizing character, when proposing self-financing instruments via m

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Wahyuni, Anna Tri, Masfuri Masfuri, and Liya Arista. "FAKTOR-FAKTOR YANG MEMPENGARUHI MORTALITAS PADA PASIEN DENGAN FRAKTUR COSTA: Literature Review." Jurnal Keperawatan Widya Gantari Indonesia 6, no. 2 (2022): 157. http://dx.doi.org/10.52020/jkwgi.v6i2.4151.

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FAKTOR-FAKTOR YANG MEMPENGARUHI MORTALITAS PADA PASIEN DENGAN FRAKTUR COSTA: Literature Review Anna Tri Wahyuni1), Masfuri2), Liya Arista3)1,2,3 Fakultas Ilmu Keperawatan Universitas Indonesia ABSTRAK Cedera paling umum yang terjadi pada trauma tumpul adalah fraktur costa (patah tulang iga/rusuk) dimana mekanisme cedera berpotensi mengancam jiwa. Pasien fraktur costa yang menunjukkan tingkat keparahan trauma lebih dari 90% melibatkan kepala, perut dan ekstremitas. Nyeri yang dirasakan akibat dari fraktur costa berkontribusi pada gangguan pernafasan, peningkatan resiko pneumonia dan gagal nafas

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Motzer, Robert J., Axel Bex, Paul Russo, et al. "Adjuvant Nivolumab for Localized Renal Cell Carcinoma at High Risk of Recurrence After Nephrectomy: Part B of the Randomized, Placebo-Controlled, Phase III CheckMate 914 Trial." Journal of Clinical Oncology, September 20, 2024. http://dx.doi.org/10.1200/jco.24.00773.

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PURPOSE CheckMate 914 is a two-part, randomized phase III trial evaluating adjuvant nivolumab plus ipilimumab (part A) or adjuvant nivolumab monotherapy (part B) versus placebo in mutually exclusive populations of patients with localized renal cell carcinoma (RCC) at high risk of postnephrectomy recurrence. Part A showed no disease-free survival (DFS) benefit for adjuvant nivolumab plus ipilimumab versus placebo. We report results from part B. METHODS Patients were randomly assigned (2:1:1) to nivolumab (240 mg once every 2 weeks for up to 12 doses), placebo, or nivolumab (240 mg once every 2

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SARMA, SHOHINEE, BENAZIR HODZIC-SANTOR, MICHAEL COLACCI, et al. "914-P: Association of Sodium–Glucose Cotransporter 2 Inhibitors with Risk of Diabetic Ketoacidosis among Hospitalized Patients—A Multicentre Cohort Study." Diabetes 73, Supplement_1 (2024). http://dx.doi.org/10.2337/db24-914-p.

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Importance: Sodium glucose co-transporter-2 (SGLT-2) inhibitors are being used among hospitalized patients, but there is no real-world empiric data on the risk of diabetic ketoacidosis (DKA) in-hospital. Objective: To assess the risk of DKA with SGLT-2 inhibitor use during hospital stay. Design, Setting, Participants: We conducted a multi-centre cohort study of hospitalized patients in 19 hospitals in Canada between January 1, 2015 and December 31, 2021. We included patients over age 18 years with type 2 diabetes mellitus who received an SGLT-2 inhibitor or a dipeptidyl peptidase-4 (DPP-4) inh

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Thi Thuy Quynh, Nguyen, Pham Le Ngoc Han, Vo Khanh Tam, Phung Thi Kim Hue, and Tsai -Lien Huang. "Microarray Data Analysis of as-induced Rice Roots by using Easygo and Mapman Softwares." VNU Journal of Science: Natural Sciences and Technology 35, no. 3 (2019). http://dx.doi.org/10.25073/2588-1140/vnunst.4860.

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Rice is one of the most important crops in Asian countries such as China, Vietnam... Many recent reports indicate that the arsenic content in rice exceeds the threshold and affects human health. Studying of molecular mechanisms and finding the arsenic resistance genes in rice which is extremely important and urgent. In this study, we analyzed the transcriptional changes of arsenic-treated rice root cells during 24 hours by microarray technique. Results showed that a large number of the differentially expressed genes (720 genes). EasyGO and Mapman softwares are powerful tools in analyzing micro

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Raffa, Taylor, Parker Chang, Babak Sarani, and Susan Kartiko. "Surgical Stabilization of Rib Fractures: A Review of the Indications, Technique, and Outcomes." Medical Research Archives 11, no. 11 (2023). http://dx.doi.org/10.18103/mra.v11i11.4694.

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Rib Fractures are a common injury in trauma patients and affect 10% of all injured patients who require admission to the hospital. Currently, there is no consensus on the most efficacious treatment for rib fractures with the debate comparing non-surgical versus surgical management. Medical management of rib fractures often requires admission to the intensive care unit with a focus on pain control to allow good pulmonary hygiene. Pain control involved a multimodal approach with current techniques including epidural anesthesia and paravertebral blocks. Although many patients recover with medical

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С.В., Артюхов. "СОВРЕМЕННЫЕ МЕТОДИКИ ЛЕЧЕНИЯ РАКА ЛЕВЫХ ОТДЕЛОВ ТОЛСТОЙ КИШКИ С ОСТРОЙ КИШЕЧНОЙ НЕПРОХОДИМОСТЬЮ". 7 липня 2017. https://doi.org/10.5281/zenodo.824233.

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© Артюхов С.В., 2017 г. <strong>УДК 617-089:616-06:616.34</strong> С.В. Артюхов <strong>СОВРЕМЕННЫЕ МЕТОДИКИ ЛЕЧЕНИЯ РАКА ЛЕВЫХ ОТДЕЛОВ ТОЛСТОЙ КИШКИ С ОСТРОЙ КИШЕЧНОЙ НЕПРОХОДИМОСТЬЮ </strong> ГУЗ «Городская Александровская больница», Санкт-Петербург Показана возможность и целесообразность выполнения двухэтапных операций – первично формированием разгрузочной и последующей радикальной операцией в одну госпитализацию. Эндовидеохирургия позволяет выполнить этапы оперативного лечения кишечной непроходимости при раке ободочной в более ранние сроки. Применение двухмоментных операций с первичным фор

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