Relevant bibliographies by topics / 93-531

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Academic literature on the topic '93-531'

Author: Grafiati
Published: 4 June 2021
Last updated: 5 February 2022

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Journal articles on the topic "93-531"

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Tarantino, Michael D., David H. Henry, Ronald S. Go, et al. "Health-Related Quality of Life (HRQoL) in Patients with Chronic Immune Thrombocytopenic Purpura (ITP): Interim Results from an Open-Label Study of AMG 531." Blood 110, no. 11 (2007): 1324. http://dx.doi.org/10.1182/blood.v110.11.1324.1324.

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Abstract The ITP Patient Assessment Questionnaire (ITP-PAQ) was developed to complement clinical data by assessing multiple facets of disease-specific HRQoL in adult patients with chronic ITP (Mathias et al., Health Qual Life Outcomes, 2007). Here we present interim results from an ongoing, open-label extension study that will evaluate the ability of AMG 531 to improve their HRQoL in the long-term. AMG 531 is a novel thrombopoiesis-stimulating peptibody that is being studied for its ability to increase platelet production by stimulating the thrombopoietin receptor. Adult chronic ITP patients receiving AMG 531 completed the ITP- PAQ at baseline, and weeks 4, 12, 24, and every 12 weeks thereafter. The ITP-PAQ consists of 44 items and 10 scales. Data have been assessed for this interim analysis through week 48, a time-point with reasonable patient numbers at the time of the data cut-off. Mean scores at each assessment, and changes in mean scores from baseline to week 48 were calculated, with positive changes in mean score indicating improvement in HRQoL. Compliance rates for the ITP-PAQ were 95% at baseline, 93% at week 4, and 83% at week 48. Over the 48-week period, results demonstrated an upward trend for the scale scores (see Table). The greatest improvements were reported in the Symptoms, Bother, Activity, Reproductive Health, and Overall Quality of Life scales, particularly during the first 4 weeks of the study. Changes in mean score from baseline to week 48 were significantly increased for Symptoms, Bother, Fatigue, Activity, Fear, Psychological Health, Work, Social Activity, and Overall Quality of Life. ITP patients receiving AMG 531 had an initial, yet sustained, improvement in ITP-PAQ scores. Subsequent analyses of results collected in this ongoing study will be used to substantiate our findings, and the therapeutic benefit of AMG 531 on HRQoL in patients with chronic ITP will be provided by correlations with clinical data. ITP-PAQ Scale Scores a by Assessment and Change in Mean Scores from Baseline
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Ommundsen, Reidar, and Knud S. Larsen. "Attitudes toward Illegal Immigration in Scandinavia and United States." Psychological Reports 84, no. 3_suppl (1999): 1331–38. http://dx.doi.org/10.2466/pr0.1999.84.3c.1331.

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531 undergraduate students ( M age = 23.4 yr.) from the universities of Copenhagen, Oslo, and Oregon State participated in a survey on attitudes toward illegal immigrants, radicalism–conservatism, Machiavellianism, and anomie. Also, a scale on relative optimism–pessimism, past, present, and future, was included. The range of coefficients alpha for the Attitudes Toward Illegal Immigration Scale was .92 to .93. Pearson product-moment correlations for the over-all sample were significant for these scores and on radicalism–conservatism, Machiavellianism, and anomie. Correlational and regression analysis identify radicalism–conservatism as a primary predictor. National sample differences are discussed.
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Martínez-González, Luis Javier, Victor Sánchez-Conde, Jose María González-Cabezuelo, et al. "Identification of MicroRNAs as Viable Aggressiveness Biomarkers for Prostate Cancer." Biomedicines 9, no. 6 (2021): 646. http://dx.doi.org/10.3390/biomedicines9060646.

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MiRNAs play a relevant role in PC (prostate cancer) by the regulation in the expression of several pathways’ AR (androgen receptor), cellular cycle, apoptosis, MET (mesenchymal epithelium transition), or metastasis. Here, we report the role of several miRNAs’ expression patterns, such as miR-93-5p, miR-23c, miR-210-3p, miR-221-3p, miR-592, miR-141, miR-375, and miR-130b, with relevance in processes like cell proliferation and MET. Using Trizol® extraction protocol and TaqMan™ specific probes for amplification, we performed miRNAs’ analysis of 159 PC fresh tissues and 60 plasmas from peripheral blood samples. We had clinical data from all samples including PSA, Gleason, TNM, and D’Amico risk. Moreover, a bioinformatic analysis in TCGA (The Cancer Genome Atlas) was included to analyze the effect of the most relevant miRNAs according to aggressiveness in an extensive cohort (n = 531). We found that miR-210-3p, miR-23c, miR-592, and miR-93-5p are the most suitable biomarkers for PC aggressiveness and diagnosis, respectively. In fact, according with our results, miR-93-5p seems the most promising non-invasive biomarker for PC. To sum up, miR-210-3p, miR-23c, miR-592, and miR-93-5p miRNAs are suggested to be potential biomarkers for PC risk stratification that could be included in non-invasive strategies such as liquid biopsy in precision medicine for PC management.
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Brookes, Gerald B. "The Role of Vestibular Nerve Section in Meniere's Disease." Ear, Nose & Throat Journal 76, no. 9 (1997): 652–63. http://dx.doi.org/10.1177/014556139707600910.

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The role of vestibular nerve section (VNS) surgery in the management of Meniere's disease is considered by prospective analysis of a large series of 531 patients treated by the author over a period of 11 years. Twenty-seven percent were referred by their primary care physicians, while the rest were secondary (45.6%) or tertiary (27.3%) referrals. Overall, 62 (11.7%) Meniere's patients underwent 63 VNS procedures. This surgery was undertaken more frequently in the secondary and tertiary referral patients (14.2%) than in the primary referrals (5.5%). The retrolabyrinthine technique was the preferred approach in almost 90% of ears. The results and complications of these and other surgical options are discussed in an attempt to define the present role of VNS in intractable Meniere's disease. Vertigo was abolished after VNS in 93% of cases. Compensation was significantly impaired in 12.9%. All these patients had contralateral Meniere's disease or marked labyrinthine hypofunction. Although highly effective and associated with few postoperative complications, VNS is generally reserved for sac failures, though may be appropriate as a primary procedure in severe unilateral cases.
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Jain, Vipin, Jennifer A. Brancel, David A. Bullard, Michael R. Sayre, Todd F. Breaux, and Michael F. Uphus. "14. Health Related Quality of Life Among Survivors of Prehospital Cardiac Arrest." Prehospital and Disaster Medicine 11, S2 (1996): S39. http://dx.doi.org/10.1017/s1049023x00045830.

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Purpose: The purpose of this study was to measure the quality of life of cardiac arrest long-term survivors.Design: Prospective outcome evaluation.Setting: The emergency medical system of a mid-sized city.Type of participants: Prehospital cardiac arrest victims who had a resuscitation attempt from 5/93 through 12/95 and were discharged alive. Patients <18 were excluded.Measurements: Patients were surveyed by mail. Non-responders were telephoned. The questions assessed Glasgow-Pittsburgh overall performance (GPOP) scores before and after the cardiac arrest. Additional items assessed physical, role, affective, and cognitive functioning, and global health status.Main Results: 760 cases were collected. 40 had unknown vital status at hospital discharge. The survival rate to hospital discharge for the 270 patients with cardiac etiology and initial rhythm of ventricular fibrillation was 15%, and it was 6% for the other 450 patients. Of 68 survivors, 23 died before a survey was sent; two had unknown addresses. 21 patients (49%) responded, and four refused to participate. The mean interval from cardiac arrest to survey response was 531 days. Ten reported good post-arrest GPOP scores, 5 had moderate disability, 4 severe disability, and 2 were comatose. Cognitive function was improved in 1, unchanged 6, slightly worse 7, markedly worse 4, and none in 3. Eleven patients reported feeling happy. Global healdi was excellent for 2, very good 8, good 5, fair 2, and poor 3.
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Karjalainen, Jouko, Matti Mäntysaari, Matti Viitasalo, and Urho Kujala. "Left ventricular mass, geometry, and filling in endurance athletes: association with exercise blood pressure." Journal of Applied Physiology 82, no. 2 (1997): 531–37. http://dx.doi.org/10.1152/jappl.1997.82.2.531.

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Karjalainen, Jouko, Matti Mäntysaari, Matti Viitasalo, and Urho Kujala. Left ventricular mass, geometry, and filling in endurance athletes: association with exercise blood pressure. J. Appl. Physiol. 82(2): 531–537, 1997.—We studied whether left ventricular (LV) mass and concentricity [relative myocardial volume (RMV)] are associated with exercise blood pressure (BP) in athletes. LV structure and filling were evaluated by Doppler echocardiography and BP in maximal bicycle ergometry and isometric handgrip tests on 32 male endurance athletes and 15 age-matched controls. Indexed LV mass was 145 ± 14 (SD) g/m in athletes and 93 ± 20 g/m in controls. Mass was not associated with BP at rest or in low-grade exercise, but with heavier exercise loads this association strengthened in athletes, being maximal at peak exercise ( r = 0.65 for mass and 0.58 for indexed mass; P < 0.001). Multivariate analysis indicated that BP at peak exercise accounted for 34% and the amount of training for an additional 11% of the variance in indexed LV mass. RMV was 21% larger in athletes. Only the increase in systolic BP during handgrip explained significantly (19%) the variance in RMV. LV filling velocities were not associated with mass, RMV, or BP. We conclude that in endurance athletes LV mass is associated with BP in heavy dynamic exercise and LV concentricity with BP response in static exercise.
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Kohrt, H. E., R. A. Olshen, W. H. Goodson, et al. "Predicting non-sentinel lymph node involvement in breast cancer patients." Journal of Clinical Oncology 24, no. 18_suppl (2006): 531. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.531.

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531 Background: Current convention is to perform a completion axillary lymph node dissection (ALND) for invasive breast cancer (BC) patients (pts) with positive sentinel lymph node(s) (+SLN), even though <50% will have non-sentinel lymph node metastasis (+NSLN). Our goal was to develop and compare predictive models of NSLN status among +SLN pts to identify for whom completion ALND may be omitted. Methods: We constructed 3 models by recursive partitioning with receiver-operating-characteristic curves (RP-ROC), boosted classification and regression trees (CART), and a multivariate logistic regression (MLR) informed by CART. Models were developed using a multi-institutional database of 1,040 BC pts who underwent SLN biopsy and completion ALND at academic or community hospitals as part of a prospective, consented study. Accuracies were compared to the Memorial Sloan-Kettering Breast Cancer Nomogram (Nomogram). Results: 976 BC pts had evaluable SLNs and 285 had +SLNs; 101(35.4%) +SLN pts had +NSLNs. Tumor size, lymphovascular invasion (LVI), and SLN metastasis size were the best predictors of risk (multivariate P-values<0.001) of +NSLN. 39 of 156 +SLN pts (25%) with T1 tumors had +NSLNs vs. 62 of 129 (48%) with T2/T3 tumors. 73.7% with LVI vs 19.5% without LVI had +NSLNs. 4.7% of pts with isolated tumor cells, 42% with micrometastasis and 71% with macrometastasis in SLN had +NSLNs. MLR informed by CART identified 2 highly predictive variables, the LVI × size of SLN metastasis [OR 4.73(3.11–7.20, 95%CI), P<0.001] and tumor size × size of SLN metastasis [OR 1.18(1.10–1.26, 95%CI), P<0.001]. While RP-ROC and boosted CART stratified pts into low-risk (4.3%-9.9%), moderate-risk (33.3%-42.9%), and high-risk (62.2%-93%) groups, MLR predicted NSLN status with accuracy superior to RP-ROC, boosted CART, and the Nomogram: 83.3%, 76.7%, 67.7%, and 76.7%, respectively, after 10-fold cross validation. The Nomogram’s sensitivity was significantly inferior to those of RP-ROC, boosted CART, and MLR: 53.8%, 78.8%, 78.2%, and 78.0%, respectively. Conclusions: In pts with +SLNs, interactions between clinicopathologic characteristics are highly informative in predicting risk of +NSLN. However, neither our methods nor the Nomogram achieved sufficient accuracy to recommend a change in current clinical practice. No significant financial relationships to disclose.
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8

Mohammed, Getachew A., Masaki Hayashi, Christopher R. Farrow, and Yasuhide Takano. "Improved characterization of frozen soil processes in the Versatile Soil Moisture Budget model." Canadian Journal of Soil Science 93, no. 4 (2013): 511–31. http://dx.doi.org/10.4141/cjss2012-005.

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Mohammed, G. A., Hayashi, M., Farrow, C. R. and Takano, Y. 2013. Improved characterization of frozen soil processes in the Versatile Soil Moisture Budget model. Can. J. Soil Sci. 93: 511–531. Soil freezing and thawing influence the infiltration of rain and snow melt water and subsequent redistribution, runoff generation, and a host of other processes. Accurate characterization of frozen soil processes in hydrological models is important for their use in managing agricultural activities and water resources. The Versatile Soil Moisture Budget (VSMB) is a relatively simple soil water balance model, which has been widely used in Canada for several decades, but its application has primarily been for crop-growing seasons. We have modified the VSMB to include new algorithms for snow accumulation and melt, soil freezing and thawing, and snowmelt infiltration and runoff; and evaluated its performance using field data from a grassland site in Alberta. The new VSMB model simulates snow processes with reasonable accuracy and predicts the day of thawing within several days of observation. It also estimates the amount of runoff and its inter-annual variability reasonably well, although the model still has limitations in accurately predicting the vertical distribution of water content. Despite these limitations, the model will be useful for estimating the amount of snowmelt runoff that provides the critical water inputs to wetlands and dugouts, and for understanding the effects of landuse variability on these processes.
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Hilaire, Rolston St, and William R. Graves. "Regional Differences in Plant Development, Water Relations, and Chloroplast DNA of Hard Maples." HortScience 33, no. 3 (1998): 456d—456. http://dx.doi.org/10.21273/hortsci.33.3.456d.

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Principal component analysis of foliar traits of hard maples (Acer saccharum Marsh. and Acer nigrum Michx. f.) near 43°N latitude clustered data into two populations composed of trees from different geographical regions. Seedlings from these two regions, and a third, geographically intermediate region, were grown in a greenhouse for 2 years with two irrigation frequencies to assess regional differences in plant development and water relations. Leaves from the most western region (west of 93°W longitude) had the highest specific mass (5.97 mg/cm2), trichome frequency (531/cm2), and stomate frequency (628/cm2). Across regions, plants irrigated frequently had more stomates (596/cm2) than plants irrigated sparsely (483/cm2). Traits similar across regions but higher with frequent irrigation included surface area and mass of lamina, shoot-to-root ratio, the ratio of lamina area to stem xylem diameter, and leaf water potential. Sparse irrigation caused a comparatively large decrease in stomatal conductance of plants from the most western region, and pressure-volume analysis showed no regional or irrigation effects on leaf osmotic potential at full turgor. Identical banding patterns resulted when Hinf I digested the PCR-amplified trnL-trnF intergenic spacer region of chloroplast DNA from each region; work with the rpL16 and ndhA introns is proceeding. Trichome frequency on abaxial leaf surfaces, which differs regionally both in nature and in controlled environments, is the most consistent character we have measured for discerning populations.
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Cudd, T. A., and C. E. Wood. "Thromboxane A2 receptor antagonism prevents hormonal and cardiovascular responses to mineral acid infusion." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 267, no. 5 (1994): R1235—R1240. http://dx.doi.org/10.1152/ajpregu.1994.267.5.r1235.

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Small infusions of strong acid create large elevations in heart rate (HR), mean arterial pressure (MAP), adrenocorticotropic hormone (ACTH), cortisol, and thromboxane A2 (TxA2). We hypothesized that TxA2 is responsible for these hormonal and hemodynamic responses. Conscious sheep received HCl (1 N, 1 ml/min for 30 min) with or without receiving SQ-29548 [a TxA2/prostaglandin (PG) H2 receptor antagonist]. HCl increased TxB2 from 133 +/- 44 to 1,213 +/- 531 (SE) pg/ml while SQ-29548 + HCl increased TxB2 from 141 +/- 41 to 1,051 +/- 518 pg/ml. HCl decreased pH (7.464 +/- 0.015 to 7.413 +/- 0.011), arterial PCO2 (31.6 +/- 1.3 to 25.9 +/- 1.8 mmHg), and arterial PO2 (98.0 +/- 2.2 to 90.5 +/- 3.2 mmHg), and increased MAP (75 +/- 2 to 88 +/- 5 mmHg), HR (72 +/- 4 to 93 +/- 8 beats/min), hematocrit (25 +/- 1 to 29 +/- 2%), ACTH (154 +/- 41 to 549 +/- 217 pg/ml), and aldosterone (25 +/- 1 to 151 +/- 74 pg/ml) while these responses were prevented by SQ-29548. SQ-29548 reduced but did not prevent the cortisol response to HCl (9 +/- 2 to 23 +/- 10 ng/ml compared with 6 +/- 2 to 17 +/- 4 pg/ml after SQ-29548). K+ and aldosterone also increased after the end of SQ-29548 + HCl treatment (4.0 +/- 0.1 to 4.5 +/- 0.1 meq/l and 53 +/- 21 to 147 +/- 61 pg/ml, respectively). We conclude that TxA2 mediates the blood gas, MAP, HR, ACTH, and aldosterone responses to HCl infusion.(ABSTRACT TRUNCATED AT 250 WORDS)
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Dissertations / Theses on the topic "93-531"

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La, Russo Aresta. "Second Generation Navajo Relocatees: Inheriting Intergenerational Losses Due to P.L. 93-531." Diss., The University of Arizona, 2015. http://hdl.handle.net/10150/560810.

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This study examines the impacts of the United States federal policy Public Law 93-531, the Navajo Hopi Land Settlement Act, which was passed by Congress in 1974. P.L. 93-531 forced many Navajo families and their children who had resided on their traditional homeland for generations to relocate elsewhere. Today, Navajo residents who were minors when they relocated with their parent(s) find themselves dispossessed of their cultural heritage. Basically, P.L. 93-531 dispossessed and displaced the Navajo minors (now adults) from their inherent traditional homelands, thus creating a second generation of Navajo relocatees. The relocation plan was not inclusive of second generation Navajo relocatees as stakeholders, leaving them in an indeterminate legal, economic, political, and social state. The primary questions addressed are these, 1) How has the relocation experience, due to Public Law 93-53, impacted the lives of second generation Navajo children, now adults, living in towns or cities off the Navajo Nation? What have been the perspectives and challenges of the participants after relocation? 2) What has the federal and Navajo government’s role been in the lives of Children of Relocation? The study utilizes a modified theoretical framework, Peoplehood Matrix, which encompasses the components of, language, ceremonial cycle, land, and sacred history, with the addition of livelihood. The components of the modified Peoplehood Matrix are interwoven and dependent upon one another which contribute to a group or individuals identity (Holm, Pearson and Chavis 2003). Qualitative and quantitative methodologies of collecting artifacts, a Q-method survey, and in-depth interview are used to study the second generation Navajo relocatees as adults living away from the Navajo Nation to document the challenges they experienced as a result of compulsory relocation. Although few studies address Navajo adult relocatees, there are no significant studies addressing second generation Navajos relocatees.
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Davis, James Joe. "The Effects of Coalition Building on Public Law 93-531: The Navajo and Hopi Land Settlement Act of 1974." Diss., Tucson, Ariz. : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1278%5F1%5Fm.pdf&type=application/pdf.

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Books on the topic "93-531"

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Affairs, United States Congress Senate Select Committee on Indian. Navajo-Hopi Relocation Housing Program Reauthorization Act of 1991: Hearing before the Select Committee on Indian Affairs, United States Senate, One Hundred Second Congress, first session, on S. 1720, to amend Public Law 93-531 (25 U.S.C. 640d et seq.) to reauthorize appropriations ... for fiscal years 1992, 1993, 1994, and 1995; September 19, 1991, Washington, DC. U.S. G.P.O., 1991.

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COM (93) 531 Final, Brussels, 26.04 [April].1994: Report from the Commission (COM (93) 531 Final, Brussels, 26.04 [April].1994). European Communities / Union (EUR-OP/OOPEC/OPOCE), 1994.

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Com (96) 531 Final, Brussels, 31.10.1996 (COM (93) 28 Final - Vol.12, Brussels, 2 April 1993). Stationery Office Books, 1996.

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Book chapters on the topic "93-531"

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"from hypoglycaemia and was unaware of his actions. The judge refused to leave that defence to the jury. Held, allowing the appeal, the arguments put to the judge failed to distinguish between hyperglycaemia and hypoglycaemia, the former being too much sugar in the blood, and the latter too little. Hyperglycaemia might raise difficult problems about the M’Naghten Rules and verdicts of not guilty by reason of insanity. Hypoglycaemia was not caused by the initial disease of diabetes, but by the treatment in the form of too much insulin, or by insufficient quality or quantity of food to counterbalance the insulin. Generally speaking, that would not give rise to a verdict of not guilty by reason of insanity but would, if it were established and showed that the necessary intent was or might be lacking, provide a satisfactory defence to an alleged crime such as theft, due to lack of mens rea. Those simple facts would be plain to anyone who troubled to read Quick (1973) 57 Cr App R and Hennessy [1989] 1 WLR 287. In the present case, the problem was hypoglycaemia and the judge had to decide whether, on the evidence, there was a prima facie case for the jury to decide whether the defendant was suffering from its effects and, if so, whether the Crown had shown that he had the necessary intent under the Theft Act. It was not doubted that the defendant was a diabetic and there was evidence that he might have been suffering from the effects of a low blood sugar level at the relevant time. That evidence should have been left to the jury. Notes and queries 1 In RvT [1990] Crim LR 256, the court accepted evidence that post-traumatic stress disorder could give rise to automatism. By contrast, in R v Sandie Smith [1982] Crim LR 531, evidence of severe pre-menstrual tension was not accepted as giving rise to automatism. Aside from the issue of whether there was sufficient evidence of automatism in the latter case, the determining factor was the court’s desire to exercise some jurisdiction over the accused. If a plea of automatism is successful the defendant is free to go – the courts cannot compel him or her to receive treatment for the condition giving rise to the automatism. Self-induced automatism." In Sourcebook Criminal Law. Routledge-Cavendish, 1996. http://dx.doi.org/10.4324/9781843143093-93.

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