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Dissertations / Theses on the topic 'A/H1N1 influenza antigen'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

Lau, Siu-ying, and 劉韶瑩. "Characterizations of antigenic and receptor binding properties of avian H5N1 and 2009 pandemic H1N1 viruses." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47165078.

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Avian H5N1 viruses have perpetuated in poultry and caused sporadic human transmission since 1997. Vaccine candidates for the potential pandemic caused by H5N1 viruses have been continuously updated by World Health Organization. Multiple genetic lineages of H5N1 viruses which co-circulate and rapidly evolve in different regions, together with periodic population replacement of newly emerged genetic and antigenic variants in the field, pose great challenge for H5N1 vaccine candidate selection. The complexity of avian H5N1 viruses evolution raises an important issue for studying antigenic proper

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2

Yang, Zheng, and 楊爭. "Identification of non-HIV-derived (poly)peptides as primary immunogens for HIV-1 vaccine development and localization of two dominant ADCC epitopes on hemagglutinin antigen of pandemic H1N1 influenza virus." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/208007.

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Development of effective vaccines against mutable viruses (i.e HIV-1 and influenza) remains a big challenge. Antibody-dependent cell-mediated cytotoxicity (ADCC) has been found to be a key component of immune protection against viral infections in vivo. Therefore, vaccine immunogens that elicit broadly neutralizing antibodies with high ADCC are desired for vaccine development. This study is to identify primary immunogens that can initiate somatic maturation of germline antibodies of known broadly neutralizing HIV-1 antibodies (bnAbs) for HIV vaccine development and to localize dominant ADCC ep

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3

Osores, Plenge Fernando, Benavides Jorge Gómez, Ognio Luis Suárez, Sánchez César Cabezas, Rosas Jorge Alave, and Vargas Ciro Maguiña. "Un nuevo virus A/H1N1, una nueva pandemia: Influenza un riesgo permanente para una humanidad globalizada." Colegio Médico del Perú, 2014. http://hdl.handle.net/10757/323238.

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La influenza es una enfermedad altamente infectocontagiosa de la cual se tienen registros históricos descriptivos desde la época griega y de certeza etiológica tan solo hace casi ocho décadas atras. Su agente causal es el virus del influenza de los que se conoce exiten tres grandes tipos: A B y C. El tipo A tiene la propiedad de circular por diversos reservorios biológicos, tales como el hombre, los cerdos y las aves, entre otros. Representa además una elevada variabilidad genética lo que le permite continuos cambios o derivas antigénicas menores responsables de la influenza humanas ep

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4

Caetano, Marco Túlio Peres. "Modelagem matematica da Influenza A(H1N1)." [s.n.], 2010. http://repositorio.unicamp.br/jspui/handle/REPOSIP/307205.

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Orientador: Hyun Mo Yang<br>Dissertação (mestrado profissional) - Universidade Estadual de Campinas, Instituto de Matematica, Estatistica e Computação Cientifica<br>Made available in DSpace on 2018-08-15T15:17:49Z (GMT). No. of bitstreams: 1 Caetano_MarcoTulioPeres_M.pdf: 770219 bytes, checksum: 1bbe772b6e5adcdbba5e870758a93226 (MD5) Previous issue date: 2010<br>Resumo: Este trabalho tem por finalidade modelar a Influenza A(H1N1). Utilizando equações diferenciais e fundamentando-se nos aspectos biológicos do processo contagioso, obtemos um sistema dinâmico. A evolução da doença dentro de uma

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5

Mahallawi, Waleed. "Natural immunity to influenza virus in humans following 2009 pandemic H1N1 influenza." Thesis, University of Liverpool, 2013. http://livrepository.liverpool.ac.uk/13137/.

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Influenza is a highly contagious and acute respiratory infection caused by influenza virus in the mucosa of the respiratory tract. Both seasonal and pandemic influenza continue to cause substantial morbidity and mortality in humans. The 2009 pandemic H1N1 (pH1N1) influenza and the potential of a highly pathogenic avian H5N1 (aH5N1) pandemic highlighted the need for effective preventative strategies. Understanding the development of natural immunity following the pH1N1 pandemic may provide important information on host protective immunity in humans, which could inform future more effective vacc

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6

Fernandes, Andrea Rolão. "O vírus Influenza - A (H1N1): tradução e glossário." Master's thesis, Universidade de Aveiro, 2010. http://hdl.handle.net/10773/4036.

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Mestrado em Tradução Especializada<br>Com este projecto, realizado no final do Mestrado em Tradução Especializada, procurou-se descrever e reflectir sobre os processos tradutológico e terminológico que regeram quer o trabalho de tradução científica, quer o de criação de um glossário, efectuados a partir de textos ligados ao Vírus A (H1N1): o de Robert Cohen, intitulado «Grippe A (H1N1)», da revista Archives de Pédiatrie (volume 16, nº 10, de 2009), disponível no site de ScienceDirect; o de Anne-Cécile. Jeannot et al., intitulado «Premiers cas de transmission secondaire en France du nouveau vir

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7

Pao, Hsing C. "Genesis of the 1918 H1N1 Spanish influenza into the 2009 swine origin influenza." Diss., [La Jolla] : University of California, San Diego, 2009. http://wwwlib.umi.com/cr/ucsd/fullcit?p1473083.

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Thesis (M.S.)--University of California, San Diego, 2009.<br>Title from first page of PDF file (viewed Feb, 1, 2010). Available via ProQuest Digital Dissertations. Includes bibliographical references (p. 46-49).

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8

Li, Zhiyuan, and 李致媛. "Impacts on influenza A(H1N1)pdm09 infection from seasonal influenza vaccine and related regional factors : systematic review and meta-analyses." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193796.

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BACKGROUND Influenza is an infectious disease that has significant public health impact due to its high prevalence and mortality. In early 2009, a novel influenza A(H1N1) virus emerged in Mexico and the USA, then rapidly spread worldwide and caused the first influenza pandemic of the 21st century. However, it is still controversial that whether seasonal influenza vaccine can provide a cross-protection against influenza A(H1N1) pdm09 infection. Since the 2009 pandemic occurred, numbers of studies focusing on this issue have been published, yet no confirmed conclusion was drawn. Therefore, furt

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Casalegno, Jean-Sébastien. "Étude de la pathogénicité des virus Influenza A/H1N1." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10047.

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La grippe est une infection respiratoire aiguë, due au virus Influenza, qui touche en moyenne chaque hiver 2,5 millions de personnes. C'est un enjeu de santé publique majeur par son impact économique et en santé humaine. Les traitements actuellement disponibles contre le virus Influenza repose sur des antiviraux ciblant la neuraminidase (inhibiteur de la neuraminidase). Jusqu'en 2007 moins de 5% des souches de virus Influenza circulantes dans le monde étaient résistantes à ces INA. Contre toute attente, l'hiver 2007/2008 a été marqué par l'émergence simultanée d'une nouvelle souche apparentée

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Li, Jibin, and 李及彬. "Mechanisms underlying differential infection by pandemic H1N1 influenza A virus of human classically activated and alternativelyactivated macrophages." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B49617540.

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Macrophages have well-established roles in the primary response to pathogens and hold essential functions during innate and adaptive immunity. Under activation by different growth factors and cytokines, human monocytes have been shown to differentiate and polarize into two main types of macrophage, classically-activated macrophages (caMφ) and alternatively-activated macrophages (aaMφ), displaying distinct properties and phenotypes. For instance, caMφ secrete pro-inflammatory cytokines, whereas aaM secrete anti-inflammatory cytokines. Additionally, aaMφ displays stronger phagocytic ability an

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Luteijn, Johannes Michiel. "2009 H1N1 pandemic influenza in Europe: congenital anomaly surveillance response." Thesis, University of Ulster, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.593634.

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Summary Introduction: This thesis reports the surveillance response of the EUROCAT network of population based registries for surveillance of congenital anomalies to the 2009 H1Nl influenza pandemic. Due to the controversy around vaccinating 1st trimester pregnant women, the relationship between pandemic influenza outbreaks and congenital anomalies (CA) deserves attention. The purpose of this thesis is to improve public health practice by investigating the effect of the 2009 HiNl influenza pandemic on CA prevalence in Europe and exploring the pandemic vaccination policy and policy making with

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Kim, Mi-so, and 金美昭. "Parental characteristics towards child vaccination against pandemic influenza H1N1-2009." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B50561686.

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Background The pandemic of influenza A (H1N1-2009) virus was particularly widespread among children. Children and young adults were more likely to be infected than older adults, and infection among infants tended to lead to a higher risk of severe complications than among older children and adults. Vaccination against the virus was thus recommended as an effective countermeasure to protect these susceptible age strata from influenza infection and subsequent complications. Parental perception, attitudes and beliefs would thus play a major role in mitigating the pandemic influenza because the

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Brien, Stephanie. "Determinants of 2009 pandemic A/H1N1 influenza vaccination in Montreal." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=106462.

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To develop successful vaccination programs for influenza pandemics, it is essential to understand the neighborhood-level factors that influence vaccination. Few studies have used an immunization registry to examine the neighborhood determinants of pandemic influenza vaccination among the general population. Using individual-level vaccination data and census, survey and administrative data to estimate the population at risk, an ecological study of the neighborhood determinants of 2009 pandemic A/H1N1 influenza vaccination in Montreal was conducted. Using logistic regression, accounting for spat

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Ling, Man-to, and 凌文韜. "The role of mannose binding lectin in pandemic H1N1 influenza virus infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B50567214.

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15

Осадча, Т. І., В. С. Пінчук, Микола Дмитрович Чемич, Николай Дмитриевич Чемич та Mykola Dmytrovych Chemych. "Особливості перебігу і лікування пандемічного грипу А (H1N1)". Thesis, Видавництво СумДУ, 2011. http://essuir.sumdu.edu.ua/handle/123456789/14998.

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Pang, Bo, and 龐博. "Structural characterization of H1N1 nucleoprotein-nucleozin binding sites." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/205641.

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Although influenza is usually acute self-limiting respiratory infection, influenza viruses are among the most common pathogens that threaten the health of humans and animals worldwide. Various anti-viral therapeutic agents are currently used for treatment and prophylaxis of influenza virus, but the problem is that the targets of these drugs are easily mutated and result in resistance. Therefore, medications that have broad spectrum coverage are urgently needed to combat with the disease. Since nucleoprotein (NP), which is encoded by influenza virus genome, is regarded as a druggable target due

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17

Han, Yan, and 韩燕. "Cigarette smoke exposure modulates the inflammatory responses during pandemic H1N1 and H9N2 infection." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hdl.handle.net/10722/193423.

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Cigarette smoke displays both immunoactivating and immunosuppressive activities. Although the health risks of cigarette smoke are widely reported, the impact and mechanism of cigarette smoke exposure on inflammatory diseases are still unclear. Innate immune responses could be activated shortly after influenza A virus infection and then trigger inflammation in the lung. Until now, the effect of prior cigarette smoke on the inflammation caused by the following influenza A virus infection has not been fully understood and there is no study about the role of cigarette smoke in 2009 pandemic H1N1 (

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Hedge, Jessica. "Molecular epidemiology and evolution of the 2009 H1N1 influenza A pandemic virus." Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/15901.

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The swine-origin H1N1 influenza A pandemic virus (A(H1N1)pdm09) was detected in the human population in March 2009. Due to its antigenic novelty, the majority of individuals were susceptible to the virus and the pandemic quickly disseminated around the globe. Rapid characterization of the epidemic was required in order to help inform interventions and determine the risk posed to public health. Widespread sampling and sequencing of virus isolates enabled early characterization of the virus using phylogenetic analysis and continued surveillance over the subsequent three years of global circulati

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Miyamoto, Sho. "In vitro vRNA-vRNA interactions in the H1N1 influenza A virus genome." Kyoto University, 2020. http://hdl.handle.net/2433/253184.

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Smith, Tammie. "The 2009 H1N1 influenza A “swine flu” virus presentation in Virginia 2009." VCU Scholars Compass, 2009. http://scholarscompass.vcu.edu/etd/1990.

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Objective: 2009 H1N1 influenza was first detected in the Northern Hemisphere in April 2009. National data have suggested that the novel influenza virus disproportionately causes severe illness in children and young adults, a somewhat different presentation from traditional seasonal flu which normally strikes hardest in the very young and older adults. This may or may not be the case in Virginia, which, if it is different, may suggest a need to alter flu prevention messages and vaccine policy as the outbreak continues through the fall 2009-10 influenza season. This report examined the early pr

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Siqueira, Giselle Angélica Moreira de. "EPIDEMIA DA INFLUENZA A (H1N1) 2009 NO ESTADO DE GOIÁS/BRASIL: CASOS E ÓBITOS." Pontifícia Universidade Católica de Goiás, 2013. http://tede2.pucgoias.edu.br:8080/handle/tede/4075.

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Submitted by admin tede (tede@pucgoias.edu.br) on 2018-11-19T16:59:56Z No. of bitstreams: 1 GISELLE ANGÉLICA MOREIRA DE SIQUEIRA.pdf: 1650143 bytes, checksum: 0a85747b640c1ee6d3c2dc446dececf7 (MD5)<br>Made available in DSpace on 2018-11-19T16:59:56Z (GMT). No. of bitstreams: 1 GISELLE ANGÉLICA MOREIRA DE SIQUEIRA.pdf: 1650143 bytes, checksum: 0a85747b640c1ee6d3c2dc446dececf7 (MD5) Previous issue date: 2013-12-19<br>SIQUEIRA, Giselle Angelica Moreira de. Epidemic Influenza A (H1N1) 2009 in the state of Goiás/Brazil: cases and deaths. Dissertation (MSc in Environmental Sciences) – Catholic U

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Tse, Maying Tsemay, and 謝美盈. "Evaluation of three commercially available influenza A type-specific blocking enzyme-linked immunosorbent assays for seroepidemiologicalstudies of influenza A virus infection in pigs." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B4827382X.

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The emergence of the pandemic H1N1 2009 virus of swine-origin and its transmission back to swine highlighted the need for global surveillance of swine influenza. Serology can help to address the epidemiological situation of influenza infection. Since typical serology tests such as hemagglutination inhibition or microneutralization assays are subtype and partially virus-lineage specific, it is important to select appropriate viral antigens for such studies. A poorly chosen panel of antigens will lead to underestimation of the seroprevalence. The choice of well-matched antigen is difficult i

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Kishida, Glaucia Santos Nascimento. "Vigilância sanitária do posto aeroportuário de Guarulhos diante da pandemia de Influenza A (H1N1), 2009." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/6/6135/tde-09102011-235411/.

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Resumo Introdução: A Vigilância Sanitária se constitui como campo de intervenção da Saúde Pública tendo como uma de suas responsabilidades, garantir o controle sanitário de aeroportos e a proteção da saúde dos viajantes. Objetivo: Neste sentido, o presente estudo teve como objetivo conhecer, descrever e analisar a prática sanitária adotada frente à Pandemia de Influenza A (H1N1) 2009, pela Vigilância Sanitária no Terminal de Passageiros do Aeroporto de Guarulhos. Metodologia: A pesquisa qualitativa foi adotada, tendo como referencial teórico as representações sociais. Utilizou-se o referencial

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Silva, Paola Cristina Resende. "Dinâmica molecular dos vírus Influenza A (H1N1) pandêmico em cinco anos de circulação no Brasil." reponame:Repositório Institucional da FIOCRUZ, 2015. https://www.arca.fiocruz.br/handle/icict/13081.

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Made available in DSpace on 2016-03-10T13:20:27Z (GMT). No. of bitstreams: 2 paola_silva_ioc_dout_2015.pdf: 5954809 bytes, checksum: 02b143793e3dbd017a0d95c668d3108c (MD5) license.txt: 1748 bytes, checksum: 8a4605be74aa9ea9d79846c1fba20a33 (MD5) Previous issue date: 2016-01-13<br>Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Rio de Janeiro, RJ, Brasil<br>A primeira detecção do vírus Influenza A (H1N1)pdm09 no Brasil aconteceu em maio de 2009, e foi seguida de uma extensa disseminação por toda a população brasileira, com grande impacto em morbidade e mortalidade. Para entender a dinâmica

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Yassine, Hadi M. "Studies on Interspecies and Intraspecies Transmission of Influenza A Viruses." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1243451078.

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Vidaña, Mateo Beatriz. "Pathogenesis of 2009 pandemic influenza a virus (H1N1) infection in the ferret model." Doctoral thesis, Universitat Autònoma de Barcelona, 2015. http://hdl.handle.net/10803/292487.

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La infección causada por el virus influenza A (VIA) causa una enfermedad aguda y recurrente con graves consecuencias sobre la salud pública mundial. El VIA es altamente contagioso y único entre las infecciones humanas presenta dos patrones epidemiológicos. Uno como epidemias estacionales anuales y otro como pandemias cada largo periodo de tiempo. En el 2009 se produjo la primera pandemia del siclo XXI, la cual presentó alta morbilidad causando más de 250.000 muertes alrededor del mundo. La mortalidad observada durante la pandemia fue similar a la observada en previas epidemias estacionales. Si

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Leung, Sze-man, and 梁詩敏. "Characterizing transmission dynamics and severity of 2009 H1N1 pandemic influenza in Hong Kong." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B49618192.

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Background: The first influenza pandemic in the 21st century, the past 2009 influenza pandemic (pdmH1N1), was caused by a novel H1N1 influenza virus. The virus was first described in April 2009 and is now believed to emerge from re-assortment of bird, pig and human flu viruses. Although this pandemic was relatively mild compared to the past pandemics, better knowledge about its characteristics in transmission dynamics and severity is still of public health interest in order to better prepare for future pandemics. Data: Clinical surveillance data were obtained from eFlu database maintained by

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Lemos, Daniele Rocha Queiroz. "CenÃrios de pandemia de Influenza A (H1N1) 2009 no CearÃ: padrÃes de morbimortalidade." Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=10220.

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INTRODUÃÃO - A gripe Ã uma doenÃa infecciosa aguda de origem viral, de distribuiÃÃo universal, que acomete o trato respiratÃrio. Segundo estatÃsticas da OrganizaÃÃo Mundial da SaÃde (OMS), cerca de 5 a 15% da populaÃÃo mundial se infecta com o vÃrus da influenza anualmente. Em marÃo de 2009, com mudanÃa no padrÃo da ocorrÃncia da influenza no MÃxico, o vÃrus da influenza A (H1N1), um quÃdruplo recombinante nunca antes visto, foi identificado atravÃs da anÃlise de amostras de secreÃÃo de nasofaringe de crianÃas americanas sintomÃticas, confirmando o vÃnculo epidemiolÃgico com os casos no MÃxico

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Rossetto, Erika Valeska. "Estudo descritivo da pandemia da Influenza A(H1N1)pdm09 no Brasil, 2009-2010." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/99/99131/tde-27112014-112900/.

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A influenza ou gripe é uma doença aguda do sistema respiratório, de alta transmisssibilidade e presente em todo o mundo. Os vírus influenza A tem freqüente capacidade de mutação antigênica, podendo assim causar epidemias sazonais e pandemias com repercussão social e econômica. O objetivo deste estudo foi descrever a pandemia de influenza pelo vírus A(H1N1)pdm09 no Brasil. Foi desenvolvido um estudo descritivo, nos anos de 2009 e 2010. Utilizou-se como fonte de dados os casos notificados no SINAN, módulo influenza pandêmica e da declaração de óbito do SIM. Foram calculadas medidas de frequência

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Pinto, Carla Cristina Clemente Rodrigues. "Pandemia influenza A/H1N1 2009 em Portugal : estratégias de intervenção e saúde pública." Master's thesis, Universidade Nova de Lisboa. Escola Nacional de Saúde Pública, 2011. http://hdl.handle.net/10362/9300.

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RESUMO - Introdução: A necessidade de gestão da ameaça de uma pandemia obriga à gestão da incerteza absoluta. O desconhecimento científico quanto a uma série de factores tais como, as características dos vírus causadores de infecções, a efectividade das medidas de prevenção e de tratamento, contribuiu para a dificuldade de actuação a vários níveis. Face à evolução da situação epidemiológica mundial no campo da gripe, Portugal reviu e adaptou o seu plano de contingência para a gripe tendo sido homologado, em Janeiro de 2006, um novo plano – Plano de Contingência Nacional do Sector da Saú

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Sydorchuk, A. S., V. D. Moskaliuk, and L. I. Sydorchuk. "Immune system dysfunction in patients with influenza virus A/H1N1 in Bukovyna region." Thesis, "Вопросы современной медицинской науки", Самарканд, Республика Узбекистан, 3-4 апреля 2015, 2015. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/8887.

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Nolting, Jacqueline Michele. "Phenotypic And Genotypic Variations In Low Pathogenic H1n1 Waterfowl-Origin Avian Influenza Viruses." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1228250591.

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Lemos, Daniele Rocha Queiroz. "Cenários de pandemia de Influenza A (H1N1) 2009 no Ceará : padrões de morbimortalidade." reponame:Repositório Institucional da UFC, 2013. http://www.repositorio.ufc.br/handle/riufc/5524.

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LEMOS, Daniele Rocha Queiroz. Cenários de pandemia de Influenza A (H1N1) 2009 no Ceará : padrões de morbimortalidade. 2013. 124 f. Dissertação (Mestrado em Saúde Pública) - Universidade Federal do Ceará. Faculdade de Medicina, Fortaleza, 2013.<br>Submitted by denise santos (denise.santos@ufc.br) on 2013-08-05T11:31:19Z No. of bitstreams: 1 2013_dis_drqlemos.pdf: 1594395 bytes, checksum: 4f8bebd5eeb3cfc329bf36d47719a9ce (MD5)<br>Approved for entry into archive by Erika Fernandes(erikaleitefernandes@gmail.com) on 2013-08-06T11:51:19Z (GMT) No. of bitstreams: 1 2013_dis_drqlemos.pdf: 1594395 byt

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DI, MARTINO ANGELA. "Genetic characteristics of the influenza A pandemic (h1n1) 2009 virus circulating in Italy." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/1386.

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I virus influenzali sono responsabili di epidemie annuali e di più rare pandemie occasionali, che in passato hanno causato la morte di milioni di persone. La comparsa di nuovi ceppi virali rappresenta una continua minaccia per la salute pubblica e una sfida per la comunità scientifica. La recente pandemia influenzale, causata da un virus di sottotipo A/H1N1 di origine suina, costituisce un ulteriore strumento per lo studio dei fattori di virulenza e della diffusione dell'infezione in preparazione a futuri eventi pandemici. Nell'ambito dell’attività di sorveglianza virologica dell'influenza,

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Devereaux, Alana. "Public Health Nurses' Experiences during the H1N1/09 Response." Thesis, Université d'Ottawa / University of Ottawa, 2016. http://hdl.handle.net/10393/35260.

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The H1N1/09 (sub-type A) virus was declared to be a pandemic influenza on June 11th, 2009. In response, Canadian public health agencies planned mass vaccination clinics to protect the public. However, little information existed to aid in the planning of mass vaccination clinics, as they had not been used in previous pandemic flu outbreaks. This was further complicated by fear of a limited vaccine supply and nurse shortages. Public health nurses (PHNs), as the largest group of public health professionals were pivotal in implementing the mass vaccination clinics. Yet, the available evidence indi

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Seblova, Dominika. "Influenza Vaccination in Persons With and Without Targeted Medical Conditions : A population-based study of the 2009/2010 influenza season in Stockholm County." Thesis, Stockholms universitet, Centrum för forskning om ojämlikhet i hälsa (CHESS), 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-110736.

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Silva, Sarah Giarola. "Caracterização fenotípica e funcional da resposta imune de voluntários imunizados contra influenza A (H1N1)pdm09." s.n, 2015. https://www.arca.fiocruz.br/handle/icict/12505.

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Corrêa, Guilherme. "BIOPOLÍTICA, GRIPE A (H1N1) E MÍDIA: O QUE PODE UM PORCO?" Universidade Federal de Santa Maria, 2012. http://repositorio.ufsm.br/handle/1/10308.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior<br>This study aimed to analyze how biopolitics encompasses the dis-media courses in a newspaper circulating in the central region of Rio Grande do Sul on Influenza A (H1N1), seeking to make visible how the institutional and discursive practices and are cross the subjects. As specific objectives, we aim to identify, in the symbolic forms of the newspaper, the ways in which population health can become the target of a power over life, and recognize the different elements disciplinary power bodies emphasized the symbolic forms and check

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Chen, Hao Hang Rachel. "The effect of pandemic influenza H1N1 viral infection on house dust mite sensitized mice." Thesis, University of British Columbia, 2016. http://hdl.handle.net/2429/58438.

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A disproportionately large number of asthmatics experienced morbidity and mortality during the 2009 H1N1 pandemic. To date, there is little information on the mechanisms behind this epidemiological and clinical observation. Using a murine asthma model, we sought to determine the effects of airway inflammation on host responses to pandemic H1N1 (pH1N1) infection. We hypothesized that mice with an allergic airway phenotype would have a greater viral susceptibility to pH1N1 infection and a dysregulated host response that prevents effective viral clearance and leads to increased burden of pulmonar

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Retamal, Miguel. "Génération d'anticorps monoclonaux neutralisants et dérive antigénique du virus influenza pandémique A(H1N1) 2009." Doctoral thesis, Université Laval, 2016. http://hdl.handle.net/20.500.11794/27334.

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Encore aujourd'hui, la prévention de la grippe par la vaccination ou les approches thérapeutiques ne sont que partiellement efficaces. Les caractères d’hypervariabilité et de transmission du virus influenza lui permettent d’infecter les populations du monde entier malgré une immunité préexistante acquise par infection ou vaccination. En 2009 une éclosion de grippe A(H1N1) au Mexique s’est répandue mondialement et est devenue la pandémie A(H1N1)pdm09. Il devenait alors impératif d’étudier davantage ce virus influenza, notamment les sites antigéniques du virus qui sont les éléments clefs dans l’

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Lee, Jinhwa. "Effects of PB1-F2 and PA-X on the pathogenicity of H1N1 influenza virus." Diss., Kansas State University, 2016. http://hdl.handle.net/2097/34617.

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Doctor of Philosophy<br>Department of Diagnostic Medicine/Pathobiology<br>Wenjun Ma<br>Influenza A virus (IAV) is a negative sense, single-stranded, segmented RNA virus with eight gene segments. It is an important respiratory pathogen which causes annual epidemics and occasional pandemics worldwide in humans and leads to considerable economic problems for the livestock industry. To control and prevent this significant disease, understanding the pathogenesis of IAVs is critical. Although some molecular mechanisms regarding virulence have been determined, IAV pathogenesis is not completely under

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Mendez, Rubio Saito Javier. "HALLAZGOS EN RADIOGRAFÍA DE TÓRAX DE PACIENTES DIAGNOSTICADOS POR SEROLOGÍA CON NEUMONÍA POR VIRUS DE LA INFLUENZA “A H1N1”, INTERNADOS EN EL “CENTRO MÉDICO LIC. ADOLFO LÓPEZ MATEOS”, EN EL PERIODO QUE COMPRENDE LOS MESES DE ENERO 2009 A DICIEMBRE 2011." Tesis de Licenciatura, Medicina-Quimica, 2013. http://ri.uaemex.mx/handle/20.500.11799/13971.

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Ribeiro, Ana Cristina de Medeiros. "Soroproteção reduzida após a vacinação sem adjuvante contra influenza pandêmica A/H1N1 em pacientes com artrite reumatoide." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5164/tde-09082013-134250/.

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Introdução: A vacinação contra a influenza pandêmica A/H1N1 resultou em soroproteção em mais de 85% dos indivíduos saudáveis. Entretanto, dados em pacientes com artrite reumatoide (AR) são escassos. Objetivos: O objetivo deste estudo é avaliar a imunogenicidade e a segurança em curto prazo da vacina contra influenza pandêmica A/H1N1 em pacientes com AR e a influência da atividade da doença e da medicação nesta resposta. Métodos: Trezentos e quarenta pacientes adultos com AR em seguimento e tratamento regular e 234 controles saudáveis foram examinados antes e 21 dias após receber uma dose da va

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潘慧敏 and Wai-man Poon. "Development and evaluation of avian influenza H5 virus antigen captureELISAs for use in Avian influenza diagnosis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2003. http://hub.hku.hk/bib/B31971222.

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Hisano, Danielle Martins de Medeiros. "Imunização contra influenza pandêmica em síndrome antifosfolípide primária: gatilho para trombose e produção de autoanticorpos?" Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5164/tde-20042016-163848/.

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Os pacientes com doenças reumáticas crônicas exibem um risco aumentado de contrair infecções. Consequentemente, sua vacinação é indispensável. Há relatos da produção de anticorpos antifosfolípides e tromboses após infecções e vacinação nesta população, exceto em síndrome antifosfolípide (SAF) primária. O objetivo principal deste estudo foi avaliar a curto e longo prazos um painel de anticorpos antifosfolípides após a vacinação contra influenza A/H1N1 (sem adjuvante) em SAF primária e controles saudáveis. Quarenta e cinco pacientes com SAF primária e 33 controles saudáveis foram imunizados e

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Nguyen, Trang. "Acceptance of an Emergently Released Vaccine by the General Public: 2009 H1N1 Influenza Pandemic Vaccine." Thèse, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/23247.

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The recent experience with the 2009 H1N1 pandemic has drawn attention to the need to better understand the public’s response to emergently released vaccines (ERV). This study applied a mixed methods approach to examine the causal pathways underlying the vaccination behaviour during a public health emergency. The integrated evidence from empirical and theoretical-based findings highlights a number of factors to consider in interventions to improve vaccination rates with an ERV. These factors include: 1) providing clear risk messages around the disease and the ERV, 2) improving accessibilit

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Lobo, Renata Desordi. "Fatores de risco para aquisição de influenza A (H1N1)pdm09 entre os profissionais de saúde." Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/5/5134/tde-11082015-155615/.

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INTRODUÇÃO: Em junho de 2009 a Organização Mundial de Saúde declarou pandemia de influenza A (H1N1)pdm09. Esse novo vírus teve grande impacto na saúde mundial, foi responsável por 90% dos casos de influenza no mundo com apresentação clínica diferente da sazonal, acometendo indivíduos jovens e causando milhares de óbitos. O Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo foi referência para atendimento de casos graves. Por se tratar de um vírus novo houve controvérsias em relação a medidas de precaução e em relação ao afastamento dos profissionais de saúde (PAS). Dev

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Guissa, Vanessa Ramos. "Imugenicidade e segurança da vacina contra influenza A H1N1/2009 em pacientes com dermatomiosite juvenil." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/5/5141/tde-03122013-113148/.

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Objetivos: Avaliar a imunogenicidade e segurança da vacina anti-influenza A/H1N1 2009 em pacientes com dermatomiosite juvenil (DMJ) comparados com controles saudáveis e a possível associação entre taxas de soroconversão com dados demográficos, enzimas musculares, escores da DMJ, linfopenia e tratamento nos pacientes com DMJ atendidos em dois serviços de Reumatologia Pediátrica. Métodos: Trinta pacientes com DMJ entre 9 e 21 anos e 81 controles saudáveis foram imunizados com a vacina anti-influenza A H1N1/2009 sem adjuvante. Todos foram avaliados pré e 21 dias após a vacinação. As taxas de soro

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Bertollo, Mait. "O circuito espacial produtivo da vacina no território brasileiro e a pandemia Influenza A H1N1." Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/8/8136/tde-10022014-110210/.

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O aprofundamento da especialização produtiva em cada porção do espaço geográfico e a integração territorial de todo o sistema econômico, produtos do capitalismo contemporâneo, traz a possibilidade da unificação de setores industriais mediante o uso de redes de transporte, comercialização e acesso instantâneo a informações. Sob esse aspecto, discutiu-se o circuito espacial produtivo das vacinas no Brasil e seus respectivos círculos de cooperação; especificamente, a indústria de base química e biotecnológica produtoras e dispersoras dos vários tipos de vacinas para uso humano, cuja concepção, pe

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Dias, Ronaldo Ferreira. "Ensaio molecular para vigilância epidemiológica de gripe com ênfase no diagnóstico de Influenza A H1N1." Instituto de Tecnologia em Imunobiológicos, 2011. https://www.arca.fiocruz.br/handle/icict/6074.

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Submitted by Priscila Nascimento (pnascimento@icict.fiocruz.br) on 2013-01-02T16:53:38Z No. of bitstreams: 1 ronaldo-dias.pdf: 887777 bytes, checksum: a3e14dd05362cb54ee5b6b1de1a81dd3 (MD5)<br>Made available in DSpace on 2013-01-02T16:53:38Z (GMT). No. of bitstreams: 1 ronaldo-dias.pdf: 887777 bytes, checksum: a3e14dd05362cb54ee5b6b1de1a81dd3 (MD5) Previous issue date: 2011<br>Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil.<br>O uso de métodos moleculares tem sido apontado como uma das principais ferramentas para o diagnóstico de doenças infecc

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