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Dissertations / Theses on the topic 'A. hypogea'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

Dupont, Samuel. "Etude de la diversité microbienne associée à l'éponge carnivore Asbestopluma hypogea." Paris 6, 2013. http://www.theses.fr/2013PA066581.

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Parmi les 8500 espèces du phylum des Porifères, seules 119 éponges carnivores ont été à ce jour décrites au sein des trois familles Cladorhizidae, Esperiopsidae et Guitarridae, la plupart vivant dans les grands fonds. La découverte en 1996 de l’espèce Asbestopluma hypogea (Cladorhizidae) (Vacelet et Boury-Esnault, 1996) dans une grotte méditerranéenne à 17 mètres de profondeur au large de La Ciotat fut l’opportunité d’étudier cette minuscule éponge, capable de maintenir son cycle de vie en aquarium. Des observations par microscopie électronique à transmission des tissus d’A. Hypogea ont mis en

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2

ZAMMIT, GABRIELLE. "A non-invasive approach to the polyphasic study of phototrophic biofilms colonising Maltese hypogea." Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2010. http://hdl.handle.net/2108/1359.

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Questo studio polifasico ha permesso di descrivere i biofilm fototrofi che si sviluppano sui dipinti murali presenti negli ipogei maltesi. L’architettura dei biofilm è stata caratterizzata tramite microscopia confocale (CLSM) ed elettronica a scansione (SEM) e la distribuzione, diversità e ruolo ecologico di cianobatteri e microalghe nei biofilm studiata dal punto di vista citomorfologico e genetico. La comprensione dei processi di biodeterioramento e biomineralizzazione è stata resa possibile grazie all’applicazione di tecniche quali la microsonda a raggi X (ESEM-EDS), la fluorescenza X (μXR

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3

Santos, Adão Felipe dos [UNESP]. "Qualidade das operações agrícolas mecanizadas na cultura do amendoim com uso do direcionamento automático." Universidade Estadual Paulista (UNESP), 2016. http://hdl.handle.net/11449/143957.

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Submitted by ADÃO FELIPE DOS SANTOS null (adaofeliped@gmail.com) on 2016-09-23T12:27:56Z No. of bitstreams: 1 Dissertação Adão Felipe dos Santos - 2016.pdf: 1454186 bytes, checksum: 346d65b6c3abf44c689b0330be35777d (MD5)<br>Approved for entry into archive by Felipe Augusto Arakaki (arakaki@reitoria.unesp.br) on 2016-09-23T14:36:32Z (GMT) No. of bitstreams: 1 santos_af_me_jabo.pdf: 1454186 bytes, checksum: 346d65b6c3abf44c689b0330be35777d (MD5)<br>Made available in DSpace on 2016-09-23T14:36:32Z (GMT). No. of bitstreams: 1 santos_af_me_jabo.pdf: 1454186 bytes, checksum: 346d65b6c3abf44c689b

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4

Nascimento, Bruna de Souza. "Secagem de sementes de Arachis hipogae L. com capa protetora." Universidade Federal de São Carlos, 2009. https://repositorio.ufscar.br/handle/ufscar/4017.

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Made available in DSpace on 2016-06-02T19:56:34Z (GMT). No. of bitstreams: 1 2321.pdf: 2212590 bytes, checksum: e03a838bd999bce0488998d98b12479f (MD5) Previous issue date: 2009-02-20<br>Universidade Federal de Sao Carlos<br>Arachis hipogae L. peanut is an orthodox seed that must go through a drying process to become free from aflatoxin. The fruit is formed by a system made up by a nucleus and a resistant involucre that constitutes a heterogeneous mixture. So as to contribute to the improvement of those seeds drying, the objective of this study is to analyze the drying of the compound system

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5

Lufrani, Riccardo [Verfasser]. "The Saint-Etienne Compound Hypogea (Jerusalem) : Geological, architectural and archaeological characteristics: A comparative study and dating / Riccardo Lufrani." Göttingen : Vandenhoeck & Ruprecht, 2019. http://www.v-r.de/.

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6

Petka, William J. "Laboratory and field evaluations of Virginia-type peanut (Arachis hypogea L.) cultivars for resistance to Diabrotica undecimpunctata howardi Barber." Thesis, This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-05022009-040722/.

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7

Annerose, Daniel. "Recherches sur les mecanismes physiologiques d'adaptation a la secheresse. Application au cas de l'arachide (arachis hypogea l. ) cultivee au senegal." Paris 7, 1990. http://www.theses.fr/1990PA077110.

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L'etude des aspects physiologiques de l'adaptation a la secheresse des especes vegetales cultivees en zones semi-arides a ete appliquee au cas de l'arachide au senegal. Elle a ete realisee dans le cadre d'une demarche multidisciplinaire permettant d'aboutir a la definition d'outils efficaces pour l'amelioration de la productivite chez cette espece. Dans un premier temps une etude pluriannuelle dynamique des risques de secheresse a permis de caracteriser les formes de secheresse existantes et de clarifier les premiers objectifs a atteindre pour l'amelioration de la productivite. Les risques imp

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8

Baker, George L. "Flavor formation and sensory perception of selected peanut genotypes (Arachis hypogea L.) as affected by storage water activity, roasting, and planting date." [Gainesville, Fla.] : University of Florida, 2002. http://purl.fcla.edu/fcla/etd/UFE1000105.

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Thesis (Ph. D.)--University of Florida, 2002.<br>Title from title page of source document. Document formatted into pages; contains xii, 130 p.; also contains graphics. Includes vita. Includes bibliographical references.

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9

N'Diaye, Saliou. "La bruche de l'arachide dans un agrosystème du centre-ouest du Sénégal : contribution à l'étude de la contamination en plein champ et dans les stocks de l'arachide (Arachis Hypogea L.) par Caryedon Cerratus (Ol.)(Coleoptera, Bruchidae) : Rôle des légumineuses hôtes sauvages dans le cycle de cette bruche." Pau, 1991. http://www.theses.fr/1991PAUU3017.

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L'arachide (Arachis Hypogea), principale culture de rapport au Sénégal, subit lors des longs stockages (8 a 13 mois) de redoutables infestations de la bruche Caryedon Serratus (OL. ). Ces contaminations peuvent se développer à partir des adultes qui subsistent dans les lieux de stockage, mais comme c'est le cas chez d'autres bruchidae, l'hypothèse d'une préinfestation en plein champ n'est pas à exclure. En effet, après arrachage, les arachides sont laissés sur le champ 1 a 2 mois en andains pour le séchage, puis en meule avec leurs stockages ultérieurs. On sait par ailleurs que C. Serratus peu

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10

Fregosi, Ralph, Stuart Quan, Andrew Jackson, et al. "Ventilatory drive and the apnea-hypopnea index in six-to-twelve year old children." BioMed Central, 2004. http://hdl.handle.net/10150/610096.

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BACKGROUND:We tested the hypothesis that ventilatory drive in hypoxia and hypercapnia is inversely correlated with the number of hypopneas and obstructive apneas per hour of sleep (obstructive apnea hypopnea index, OAHI) in children.METHODS:Fifty children, 6 to 12 years of age were studied. Participants had an in-home unattended polysomnogram to compute the OAHI. We subsequently estimated ventilatory drive in normoxia, at two levels of isocapnic hypoxia, and at three levels of hyperoxic hypercapnia in each subject. Experiments were done during wakefulness, and the mouth occlusion pressure meas

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11

Eigner, Florian. "Untersuchungen am koaxialen Getriebe „HypoGear“." Technische Universität Chemnitz, 2019. https://monarch.qucosa.de/id/qucosa%3A34306.

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Auf der Suche nach immer kompakteren koaxialen Getrieben für kleine Antriebe steht eine neue Bauweise bereit. Der Foliensatz stellt kurz die Baugruppen eines solchen Getriebes vor und klärt über einige der Herausforderungen auf, die die Entwicklung beeinflussen. Weiterhin wird auf die Berechnung der verbauten Hypoidzahnradstufe eingegangen. Die Berechnung der Zahngeometrie ausgehend von den Wälz-Gleit-Körpern wird losgelöst von den Einschränkungen betrachtet, die herkömmliche Serienfertigungsverfahren mit sich bringen. Ausblickend werden die Entwicklungsschritte umrissen, die zunächst zum Prot

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12

O'Dell, Adam David. "Hypoxia." Bowling Green State University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1490629987974442.

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13

Armando, Junior Jose. "Floração em amendoim (Arachis hypogaea L.)." [s.n.], 1990. http://repositorio.unicamp.br/jspui/handle/REPOSIP/315328.

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Orientador : Maria de Fatima D. A. Pereira<br>Dissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia<br>Made available in DSpace on 2018-07-14T00:51:28Z (GMT). No. of bitstreams: 1 ArmandoJunior_Jose_M.pdf: 5717232 bytes, checksum: e905ffa01f04ec0e134e98afe2efb7d5 (MD5) Previous issue date: 1990<br>Resumo: O amendoim (Arachis hypogaea L.) é uma planta herbácea, anual, com caules eretos e prostrados, flores amarelas localizadas nas regiões axiliares, pertencente à família Leguminosae. Neste trabalho, foi estudada a influência de alguns fatores do ambiente, como o f

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14

Sathaye, S. S. "Tissue culture studies on peanut (arachis hypogaea)." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1993. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3075.

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15

Peters, Caren Lorraine. "Hypoxia in inflammation." Thesis, University of Bath, 2003. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426151.

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16

Lau, Yue-huen Thomas. "Nuclear transcription factors and hypoxia-inducible genes in chronic liver hypoxia." Click to view the E-thesis via HKUTO, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31939302.

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17

Lau, Yue-huen Thomas, and 劉汝這. "Nuclear transcription factors and hypoxia-inducible genes in chronic liver hypoxia." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B31939302.

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18

Sun, Yan Jenny. "Glycans of cationic peanut, Arachis hypogaea L., peroxidase." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp01/MQ30702.pdf.

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19

Querido, Jordan S. "Intermittent hypoxia : cardiorespiratory and cerebrovascular consequences to acute hypoxia and submaximal exercise." Thesis, University of British Columbia, 2007. http://hdl.handle.net/2429/32125.

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Intermittent hypoxia (IH) is broadly defined as repeatedly breathing decreased amounts of oxygen (hypoxia) interspersed with periods of room air breathing (normoxia). In animal, human diseased, and healthy human models, research has shown IH to negatively affect cerebrovascular vessel dilation. We have previously shown poikilocapnic (uncontrolled carbon dioxide (CO₂)) IH to blunt the vasodilatory response of a cerebral vessel during acute hypoxia. The purpose of this study was to measure the ventilatory, cardiovascular and cerebrovascular responses to: I) acute hypoxia and; II) to submaximal

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20

Smith, Quintina Denine. "From here to hypoxia." College Park, Md. : University of Maryland, 2006. http://hdl.handle.net/1903/3614.

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Thesis (M.F.A.) -- University of Maryland, College Park, 2006.<br>Thesis research directed by: Dept. of Art. Title from t.p. of PDF. Includes bibliographical references. Published by UMI Dissertation Services, Ann Arbor, Mich. Also available in paper.

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21

Holland, Jason P. "Hypoxia-Selective Copper Radiopharmaceuticals." Thesis, University of Oxford, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491536.

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This thesis presents detailed experimental and computational investigations into the chemistry of copper(II) and zinc(II) bis(thiosemicarbazonato) complexes as potential' radiopharmaceutical agents for imaging and therapy. Chapter 1 provides an introduction to the field of molecular imaging in medicine with particular emphasis on the role of positron emission tomography in oncology. Key aspects of tumour physiology are discussed, and the effects of tumour hypoxia on radiotherapy and chemotherapy are considered. A range of hypoxia-selective radiopharmaceuticals are also introduced including a r

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22

Mahamed, Safraaz. "Chemoreflex adaptations to hypoxia." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape2/PQDD_0019/MQ54186.pdf.

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23

Querido, Jordan Scott. "Hypoxia and autonomic control." Thesis, University of British Columbia, 2012. http://hdl.handle.net/2429/42530.

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Humans have a remarkable ability to cope with and survive exposure to hypoxia. Some have suggested a benefit in certain physiological systems in response to such exposure. However, the physiological response to hypoxia is multifaceted and includes an orchestrated response from many autonomic mechanisms. Thus, the purpose of this thesis was to more fully understand the human autonomic response to hypoxia as an integrated unit. Furthermore, pathological models of hypoxia provide evidence that suggests hypoxia can result in an autonomic response that outlasts the hypoxic stimulus. However, the pe

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24

Nagyova, Beatrix Valeria. "Respiratory effects of hypoxia." Thesis, University of Oxford, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320659.

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25

Dearling, Jason L. J. "Hypoxia targeting copper complexes." Thesis, University of Kent, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297352.

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26

Lau, Chi-keung, та 劉智強. "Blockade of hypoxia inducible factor-1α sensitizes hepatocellular carcinoma to hypoxia and chemotherapy". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B39634243.

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27

Shaikh, Nasir Pasha. "Herbicide and insecticide interactions in peanut (Arachis hypogaea L.)." [Gainesville, Fla.] : University of Florida, 2004. http://purl.fcla.edu/fcla/etd/UFE0004788.

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28

Mhaske, V. B. "Studies on somatic embryogenesis in peanut (arachis hypogaea L.)." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 1997. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/3222.

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29

Lau, Chi-keung. "Blockade of hypoxia inducible factor-1[alpha] sensitizes hepatocellular carcinoma to hypoxia and chemotherapy." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B39634243.

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30

Hägg, Maria. "Hypoxia-inducible factors (HIFs) and biological responses in hypoxia, inflammation and embryonic vascular development /." Göteborg: Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, the Sahlgrenska Academy at University of Gothenburg, 2008. http://hdl.handle.net/2077/9991.

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31

Wahlquist, Hanna. "Hypoxia and Angiogenesis in IUGR." Thesis, Uppsala University, Department of Medical Biochemistry and Microbiology, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-9316.

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<p>BACKGROUND: Intrauterine growth restriction (IUGR) is a condition where the infant fails to reach its genetic growth potential due to numerous factors. IUGR foetuses are associated with high perinatal mortality and morbidity. This study investigated if hypoxia might be involved during gestation, and whether if hypoxia may have an impact on the development of the placenta, through regulation of various angiogenic factors, such as HIF-1_, VEGF, PIGF, VEGFR-1 and CD31. METHOD: Each sample of placental tissue was stained by immunohistochemisty for HIF-1_, VEGF, PIGF, VEGFR-1 and CD31. Th

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32

Hobbs, Catherine E., and n/a. "Perinatal hypoxia-ischaemia : neuroprotective strategies." University of Otago. Department of Anatomy & Structural Biology, 2005. http://adt.otago.ac.nz./public/adt-NZDU20070221.145910.

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Perinatal hypoxia-ischaemia is a major cause of disability, including cerebral palsy, yet a neuroprotectant which fully protects the brain remains elusive. Following a hypoxic-ischaemic insult, striatal medium-spiny neurons and hippocampal CA1 neurons are vulnerable to a complex cascade of neurotoxic events. This cascade includes energy failure, a massive release of glutamate, the formation of free radicals and caspase activation. The overall aim of this thesis was to assess the efficacy of three potential neuroprotective strategies that target this cascade from different directions. Short-ter

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33

Raval, Raju R. "Hypoxia-mediated pathways in cancer." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433331.

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34

Talbot, Nicholas. "Pulmonary vascular responses to hypoxia." Thesis, University of Oxford, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.404270.

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35

Peansukmanee, Siriporn. "Equine chondrocyte metabolism under hypoxia." Thesis, University of Liverpool, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501589.

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The avascular nature of articular cartilage limits oxygen supply within the tissue. Cartilage, therefore, is under physiological hypoxic conditions. Oxygenation gradients are estimated from 10% at the surface to 1% at the deepest layer. Nonetheless, chondrocytes have been reported to be able to survive and are well-adapted to such an environment. We hypothesised that low oxygen tensions favour chondrocyte metabolism based on their nature and literature reviews.

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36

MacManus, Michael Patrick. "Erthropoietin, anaemia and tumour hypoxia." Thesis, Queen's University Belfast, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.335941.

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37

Jones, Richard David. "Hypoxia and the pulmonary circulation." Thesis, University of Sheffield, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301608.

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38

Padmanabha, Divya. "HIF-INDEPENDENT RESPONSES IN HYPOXIA." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3828.

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The adaptive response to hypoxia is accompanied by widespread transcriptional changes that allow for prolonged survival in low oxygen. Many of these changes are directly regulated by the conserved hypoxia-inducible factor-1 (HIF-1) complex; however, even in its absence, many oxygen-sensitive transcripts in Caenorhabditis elegans are appropriately regulated in hypoxia. To identify mediators of these non-HIF-dependent responses, I established a hif-1 mutant reporter line that expresses GFP in hypoxia or when worms are treated with the hypoxia mimetic cobalt chloride (cobalt chloride). The report

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39

Maphossa, Alexandre M. "A nuclear magnetic resonance investigation of Archis hypogaea L. (groundnut)." Thesis, University of Kent, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309779.

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40

Lim, Wei Hoong. "Stability of the storage proteins of peanut (Arachis hypogaea L.)." Thesis, University of Leeds, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426826.

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41

Cruickshank, Alan. "Peanut (Arachis hypogaea) resistance to Sclerotinia minor and S. sclerotiorum /." [St. Lucia, Qld. : s.n.], 2000. http://adt.library.uq.edu.au/public/adt-QU2001.0025/index.html.

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42

Lungu, Gina Florentina. "Role of hypoxia and hypoxia induced factors in the development of breast cancer brain metastasis." [College Station, Tex. : Texas A&M University, 2008. http://hdl.handle.net/1969.1/ETD-TAMU-3082.

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43

Knight, Laura K. "The effect of hypoxia and the transcription factor hypoxia inducible factor-1 (HIF-1) on metastasis." Thesis, University of Manchester, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502269.

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Tumour hypoxia has been widely implicated in the development of aggressive, therapy resistant malignant disease. Patients presenting with more hypoxic tumours experience higher levels of mortality compared to those with lower levels of hypoxia. The primary reason or this increased phenotype is the stabilisation of the transcription factor hypoxia inducible factor-1 (HIF-1). Upon exposure to hypoxic conditions, the alpha subunit of this heterodimer Stabilised and binds to the beta subunit. Once stabilised HIF-1 induces gene expression resulting in the Increased exproression of a number of prote

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Lim, Ai Lin. "Characterization of hypoxia-induced gene (HIG2) and hypoxia-inducible autophagy as novel pathways of tumor growth /." May be available electronically:, 2007. http://proquest.umi.com/login?COPT=REJTPTU1MTUmSU5UPTAmVkVSPTI=&clientId=12498.

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45

Taheem, Dheraj Kumar. "A role for hypoxia and hypoxia inducible factor during chondrogenesis of bone marrow mesenchymal stem cells." Thesis, King's College London (University of London), 2018. https://kclpure.kcl.ac.uk/portal/en/theses/a-role-for-hypoxia-and-hypoxia-inducible-factor-during-chondrogenesis-of-bone-marrow-mesenchymal-stem-cells(8f516122-6cd6-4c9b-91f6-bede34427fd5).html.

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Articular cartilage lesions cause pain, morbidity and may progress to osteoarthritis, which in terms of medical care, has been approximated to cost 1-2.5% of the gross national product of USA, UK, France and other countries. Current repair strategies have considerable limitations and have prompted the development of cartilage tissue engineering (CTE) approaches. One of the challenges of CTE is the expansion and differentiation of adult stem cells in vitro, into functional articular chondrocytes whilst avoiding hypertrophy. Hypoxia is an important environmental factor required for cartilage dev

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46

Essomba, Nehru Bengono. "The inheritance of four morphological traits in peanut (Arachis hypogaea L.)." Thesis, Virginia Polytechnic Institute and State University, 1987. http://hdl.handle.net/10919/90969.

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Studies of the inheritance of morphological traits contribute to the understanding of peanut genetics. Investigations of the fertility and cytogenetics of interspecific progenies between Arachis hypogaea and wild Arachis species have provided invaluable information on the phylogenetic relationships within the genus Arachis and on the amphidiploid nature of peanut. However, the inheritance of morphological traits using interspecific progenies has not been elucidated to date. The objective of this study was to identify and to analyze genetic factors controlling growth habit, stem color, root nod

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47

Aung, Tin. "Effect of relative humidity on peanut (Arachis hypogaea L.) seed deterioration /." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487687959966447.

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48

Okada, Mauricio Hideki. "Aquisição de qualidade fisiológica em sementes de amendoim (Arachis hypogaea L.) /." Botucatu, 2019. http://hdl.handle.net/11449/183577.

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Orientador: Edvaldo Aparecido Amaral da Silva<br>Banca: João Nakagawa<br>Banca: Daiani Ajala Luccas<br>Resumo: Sementes de alta qualidade fisiológica é pré-requisito para o estabelecimento da cultura e para a produção. A qualidade fisiológica das sementes é adquirida durante o desenvolvimento. O conhecimento sobre quando cada componente da qualidade fisiológica é adquirido durante a fase de maturação da semente permite um ajuste no momento ideal da colheita e consequentemente colheita no período em que a semente se encontra com o máximo de qualidade fisiológica. Portanto, o objetivo deste trab

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49

Tan, Qiulin. "Inhibition of cholesterol biosynthesis under hypoxia." Texas A&M University, 2005. http://hdl.handle.net/1969.1/3101.

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Oxygen balance is very important and tightly regulated in mammals. Under hypoxia, hypoxia inducible factor 1(HIF-1) dimerizes with hypoxia inducible factor 1± (HIF-) and activates expression of several genes. Using a mammalian two hybrid assay, we found that HIF-1 interacted with sterol response element binding protein 1a (SREBP1a). SREBP1a regulates transcription of HMG-CoA reductase via binding to the sterol response element (SRE) in the promoter region. HMG-CoA reductase is the rate-limiting enzyme in cholesterol biosynthesis. The interaction between SREBP1a and HIF-1suggests that HIF-1 may

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50

Hoenderdos, Kim. "Modulation of neutrophil degranulation by hypoxia." Thesis, University of Cambridge, 2015. https://www.repository.cam.ac.uk/handle/1810/247459.

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Neutrophils are key effector cells of the innate immune system. They employ a number of powerful ‘weapons’ to eliminate pathogens, including an array of destructive proteins packaged into distinctive granule subsets. In addition to their microbicidal activity, these granule proteins are capable of causing substantial tissue damage if inappropriately deployed. To mitigate against this possibility, most physiological stimuli induce minimal extracellular degranulation. Sites of inflammation and infection are usually hypoxic, and it has been shown that oxygen depletion compromises neutrophil funct

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