Academic literature on the topic 'A transdermal therapeutic system'

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Journal articles on the topic "A transdermal therapeutic system"

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Sahu, Mithlesh, Mithun Bhowmick, and Jagdish Rathi. "Design and evaluation of Matrix Transdermal therapeutic system of Repaglinide." International Journal of Research and Development in Pharmacy & Life Sciences 06, no. 04 (2017): 2697–705. http://dx.doi.org/10.21276/ijrdpl.2278-0238.2017.6(4).2697-2705.

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Sidorov, Aleksander V. "TRANSDERMAL FENTANYL: PHARMACOLOGICAL ASPECTS OF THERAPY IN CANCER PATIENTS. PART 1. FROM THE DEVELOPMENT OF TRANSDERMAL FENTANYL FORMULATIONS TILL META-ANALYSES OF CLINICAL TRIALS." Russian Journal of Oncology 22, no. 3 (2017): 122–30. http://dx.doi.org/10.18821/1028-9984-2017-22-3-122-130.

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There was given a review of data on pharmacology of fentanyl with focus on transdermal formulation. In the first part of the article improvements in technology of fentanyl transdermal patches were reviewed and advantages of the membrane-matrix system that are of practical use were highlighted. The results obtained from bioequivalence and therapeutic equivalence studies of traditional and improved transdermal fentanyl systems were given. Clinical trials with fentanyl transdermal patches as well as systematic reviews and meta-analyses on the efficacy and safety of transdermal fentanyl were summa
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ONO, HIDENORI, YUKA KIDA, HIROMI ONOMICHI, KENICHI MURAOKA, and KAKUJI TOJO. "Temporal Control of Transdermal Therapeutic System." KAGAKU KOGAKU RONBUNSHU 25, no. 2 (1999): 233–36. http://dx.doi.org/10.1252/kakoronbunshu.25.233.

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Sachin, Pawar* Nitin Sawle Dr. Gajanan Sanap. "Review On Transdermal Drug Delivery System." International Journal of Pharmaceutical Sciences 3, no. 1 (2025): 671–81. https://doi.org/10.5281/zenodo.14628391.

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Polymeric patches with dissolved or dispersed medication that continuously release therapeutic agents via the skin are known as transdermal drug delivery systems. Although transdermal administration has significantly advanced medical practice, it has not yet reached its full potential as a substitute for hypodermic injections and oral delivery. The idea behind TDDS is that they can deliver drugs continuously over an extended length of time, which will maintain the drug's concentration in plasma. To maintain plasma-drug levels for therapeutic efficacy, TDDS can be made to input drugs at the rig
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Kuznetsova, E. G., V. A. Ryzhikova, L. A. Salomatina, O. M. Kuryleva, and V. I. Sevastianov. "Percutaneous delivery system for nicotinamide transdermal therapeutic system." Perspektivnye Materialy 7 (2023): 46–56. http://dx.doi.org/10.30791/1028-978x-2023-7-46-56.

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Recently, antioxidants, one of which is nicotinamide, have often been used in the treatment of a number of chronic cardiovascular, autoimmune, skin diseases, and diabetes mellitus. Taking into account the frequent and long-term use of nicotinamide, it seems appropriate to the authors to create a new dosage form of a transdermal therapeutic system (TTS) capable of maintaining the required level of the drug concentration in the blood for a long time. The aim of the work was to develop and to study the functional properties of a system for percutaneous delivery of nicotinamide in vitro. Four comp
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Manthal, Aishwarya, Dr Sunayana Ghodgaonkar, Akash S. Nalawade, and Shivani B.Masal. "Recent Advancement in Transdermal Drug Delivery System." International Journal of Pharmaceutical Research and Applications 09, no. 06 (2024): 1320–29. https://doi.org/10.35629/4494-090613201329.

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The transdermal route offers several advantages over traditional drug delivery methods. These include high bioavailability, avoidance of first-pass liver metabolism, consistent drug levels in the bloodstream, and a non-invasive approach to treatment. Furthermore, transdermal drug delivery systems (TDDS) offer prolonged therapeutic effects, fewer side effects, enhanced bioavailability, improved patient adherence, and easy discontinuation of therapy. TDDS is used not only in pharmaceuticals but also in skincare and cosmetics. Research has shown that the transdermal route causes minimal skin irri
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Samiksha B. Rotake, Pooja R. Hatwar, Ravindra L. Bakal, and Nitin B. Kohale. "Transdermal drug delivery system recent advancements: A comprehensive review." GSC Biological and Pharmaceutical Sciences 28, no. 2 (2024): 059–72. http://dx.doi.org/10.30574/gscbps.2024.28.2.0269.

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"The transdermal route offers numerous benefits when compared to traditional drug delivery methods. These advantages encompass high bioavailability, the absence of first-pass hepatic metabolism, maintaining consistent drug plasma levels, and the non-invasive nature of therapy. Additionally, transdermal drug delivery systems [TDDS] provide prolonged therapeutic effects, reduced side effects, enhanced bioavailability, improved patient compliance, and easy termination of drug therapy. TDDS finds applications not only in pharmaceuticals but also in the skincare and cosmetics industries. Studies ha
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Samiksha, B. Rotake, R. Hatwar Pooja, L. Bakal Ravindra, and B. Kohale Nitin. "Transdermal drug delivery system recent advancements: A comprehensive review." GSC Biological and Pharmaceutical Sciences 28, no. 2 (2024): 059–72. https://doi.org/10.5281/zenodo.14676299.

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"The transdermal route offers numerous benefits when compared to traditional drug delivery methods. These advantages encompass high bioavailability, the absence of first-pass hepatic metabolism, maintaining consistent drug plasma levels, and the non-invasive nature of therapy. Additionally, transdermal drug delivery systems [TDDS] provide prolonged therapeutic effects, reduced side effects, enhanced bioavailability, improved patient compliance, and easy termination of drug therapy. TDDS finds applications not only in pharmaceuticals but also in the skincare and cosmetics industries. Studies ha
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Plezia, P. M., J. LinforrI, T. H. Kramer, R. P. lacono, and S. R. Hamcroff. "TRANSDERMAL THERAPEUTIC SYSTEM (FENTANYL) FOR POSTOPERATIVE PAIN." Anesthesiology 65, Supplement 3A (1986): A211. http://dx.doi.org/10.1097/00000542-198609001-00210.

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COMFORT, A. "Enhanced transport in a therapeutic transdermal system." Biomaterials 11, no. 9 (1990): 729–33. http://dx.doi.org/10.1016/0142-9612(90)90036-p.

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Dissertations / Theses on the topic "A transdermal therapeutic system"

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Jalal, Ahmed Hasnain. "Multivariate Analysis for the Quantification of Transdermal Volatile Organic Compounds in Humans by Proton Exchange Membrane Fuel Cell System." FIU Digital Commons, 2018. https://digitalcommons.fiu.edu/etd/3886.

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In this research, a proton exchange membrane fuel cell (PEMFC) sensor was investigated for specific detection of volatile organic compounds (VOCs) for point-of-care (POC) diagnosis of the physiological conditions of humans. A PEMFC is an electrochemical transducer that converts chemical energy into electrical energy. A Redox reaction takes place at its electrodes whereas the volatile biomolecules (e.g. ethanol) are oxidized at the anode and ambient oxygen is reduced at the cathode. The compounds which were the focus of this investigation were ethanol (C2H5OH) and isoflurane (C3H2ClF5O), but th
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Membrino, Michael A. "Transdermal delivery of therapeutic compounds by iontophoresis." [Gainesville, Fla.] : University of Florida, 2002. http://purl.fcla.edu/fcla/etd/UFE1000142.

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Thesis (Ph. D.)--University of Florida, 2002.<br>Title from title page of source document. Document formatted into pages; contains xvii, 283 p.; also contains graphics. Includes vita. Includes bibliographical references.
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Roxhed, Niclas. "A Fully Integrated Microneedle-based Transdermal Drug Delivery System." Doctoral thesis, Stockholm : Kungliga Tekniska högskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4484.

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Magnus, Ashley Denis. "Aspects of the bioavailability of topical corticosteroid formulations." Thesis, Rhodes University, 2013. http://hdl.handle.net/10962/d1009516.

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Two possible variables of the McKenzie/Stoughton blanching assay, namely amount applied to the test site and occlusion time have been investigated. Subsequently, two topical steroid preparations, Synalar cream (0,025% fluocinolone acetonide) and Betnovate cream (0,1% betamethasone 17-valer ate) were extemporaneously diluted with five and six placebo bases respectively. Taking cognizance of the two possible variables, these diluted preparations were assessed in vivo using a modified version of the McKenzie/Stoughton blanching assay for blanching activity over a 14 month period. It was found tha
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Zeng, Jianming. "Constrained crystallization and depletion in the polymer medium for transdermal drug delivery system." Diss., Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/5102.

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Transdermal drug delivery systems (TDS) are pharmaceutical devices that are designed to deliver specific drugs to the human body by diffusion through skin. The TDS effectiveness suffers from crystallization in the patch when they are kept in storage for more than two years. It has been reported that there are two types of crystals in the patch: needle and aggregate, and growth of drug crystals in TDS generally occurs only in the middle third of the polymer layer. In our study, fluorescence microscopy, EDS (SEM) and Raman microspectroscopy were used to further characterize the crystals. The res
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Coetzee, Hanneri. "The transdermal delivery of arginine vasopressin with pheroid technology / H. Coetzee." Thesis, North-West University, 2007. http://hdl.handle.net/10394/1491.

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Busquets, Garcia Arnau 1985. "Targeting the endocannabinoid system for therapeutic purposes." Doctoral thesis, Universitat Pompeu Fabra, 2013. http://hdl.handle.net/10803/119617.

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The endocannabinoid system is an endogenous neuromodulatory system that regulates a plethora of physiological functions, including the modulation of memory, anxiety, pain, synaptic plasticity and neuronal excitability, among others. The activation of this system through exogenous or endogenous cannabinoid agonists has been proposed as a therapeutic strategy in different pathological states, although an important caveat to their use is the possible central adverse effects, such as memory impairment, anxiety and tolerance. The activity of the endocannabinoid system has been recently found involv
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Van, Dyk Christina Petronella. "Transdermal delivery of 5-Fluorouracil with PheroidTM technology / C.P. van Dyk." Thesis, North-West University, 2008. http://hdl.handle.net/10394/1905.

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Van, der Walt Magdalena Elizabeth. "Transdermal delivery of Acyclovir and Ketoconazole by PheroidTM technology / Magdalena Elizabeth van der Walt." Thesis, North-West University, 2007. http://hdl.handle.net/10394/1937.

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Vettorato, Elisa. "Development of transdermal delivery systems for innovative clinical applications of cannabinoids." Doctoral thesis, Università degli studi di Padova, 2019. http://hdl.handle.net/11577/3422356.

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The use of cannabis for medicinal purposes is deeply rooted in history, dating back to ancient times. While there has been a strong push for legalizing medicinal cannabis and research, conclusive evidence regarding the short- and long-term health effects (harms and benefits) of cannabis use remains elusive because of a high variability when cannabinoids are administered orally or by inhalation. Transdermal delivery of cannabinoids could allow a constant, defined release of these active ingredients. The main goal of this project was to develop innovative pharmaceutical forms in order to ensure
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Books on the topic "A transdermal therapeutic system"

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Reinhard, Sittl, and Budd Keith, eds. Practice of transdermal pain therapy. Uni-Med, 2005.

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Inc, Foot Levelers, ed. Thera-ciser therapeutic exercise system. Foot Levelers, 1986.

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S, Barkin Jamie, and O'Phelan Cesar A, eds. Advanced therapeutic endoscopy. Raven Press, 1990.

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Lambris, John D., and V. Michael Holers. Therapeutic Interventions in the Complement System. Humana Press, 2000. http://dx.doi.org/10.1385/1592590179.

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Young, Wei-Chieh. Lectures on Tung's acupuncture: Therapeutic system. American Chinese Medical Culture Center, 2008.

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Lambris, John D., and V. Michael Holers, eds. Therapeutic Interventions in the Complement System. Humana Press, 2000. https://doi.org/10.1007/978-1-59259-017-9.

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Krämer, Dietmar. New Bach flower body maps: Treatment by topical application. Healing Arts Press, 1996.

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Switzerland) International Symposium Clonidine in Hypertension (1984 Geneva. Low dose oral and transdermal therapy of hypertension: International Symposium Clonidine in Hypertension, Geneva, 14th-16th June, 1984. Steinkopff, 1985.

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P, Ranchan Som. Aurotherapy: An alternate therapy system. Indian Publishers Distributors, 2001.

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Chung, RaphaelS. Therapeutic endoscopy in gastrointestinal surgery. Churchill Livingstone, 1987.

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Book chapters on the topic "A transdermal therapeutic system"

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Nimmo, W. S. "Transdermal Therapeutic Systems in Clinical Use: Development and Applications." In Transdermal Fentanyl. Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76872-9_2.

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Boekhorst, J. C., and R. G. L. van Tol. "Catapres Transdermal Therapeutic System (TTS) for Long-Term Treatment of Hypertension." In Low Dose Oral and Transdermal Therapy of Hypertension. Steinkopff, 1985. http://dx.doi.org/10.1007/978-3-642-53785-1_20.

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Levy, Drora, Peretz Glikfeld, Yona Grunfeld, et al. "A Novel Transdermal Therapeutic System as a Potential Treatment for Alzheimer’s Disease." In Advances in Behavioral Biology. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2179-8_63.

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Pastore, Michael N., and Michael S. Roberts. "Selection of Topically Applied Chemical Candidates: Transdermal Drug Delivery Systems." In Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds. Springer Japan, 2017. http://dx.doi.org/10.1007/978-4-431-56526-0_21.

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Lee, Juhee, and Jihee Kim. "Emerging Technologies in Scar Management: Laser-Assisted Delivery of Therapeutic Agents." In Textbook on Scar Management. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44766-3_50.

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AbstractTopical application of medications is difficult through intact skin due to physiological barrier of stratum corneum. Effective transdermal drug delivery system can offer distinct advantages over the topical application and oral administration of drugs. Laser systems have showed clinical benefits for patients in various types of scars for decades. In particular, the advent of fractional resurfacing advanced laser has enhanced the scar treatments dramatically. A fractional laser irradiates cells with high precision by controlling the area and degree of ablation through laser settings. In
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Katsumi, Hidemasa, Ying-Shu Quan, Fumio Kamiyama, and Akira Yamamoto. "Related Topic: Development of a Transdermal Drug Delivery System Using Self-Dissolving Microneedle Arrays Fabricated with Hyaluronic Acid." In Skin Permeation and Disposition of Therapeutic and Cosmeceutical Compounds. Springer Japan, 2017. http://dx.doi.org/10.1007/978-4-431-56526-0_23.

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Yellepeddi, Venkata K. "Nanotechnology-Based Applications for Transdermal Delivery of Therapeutics." In Novel Delivery Systems for Transdermal and Intradermal Drug Delivery. John Wiley & Sons, Ltd, 2015. http://dx.doi.org/10.1002/9781118734506.ch6.

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Nahler, Gerhard. "transdermal delivery system (TDDS)." In Dictionary of Pharmaceutical Medicine. Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_1406.

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Kumar, Amit, Kashid Saurabh Machhindra, Keerti Jain, and Awesh K. Yadav. "Transdermal Drug Delivery System." In Novel Carrier Systems for Targeted and Controlled Drug Delivery. Springer Nature Singapore, 2024. https://doi.org/10.1007/978-981-97-4970-6_5.

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Desai, Jagruti L., Tosha Pandya, and Ashwini Patel. "Nanocarriers in Transdermal Drug Delivery." In Nanocarriers: Drug Delivery System. Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-4497-6_16.

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Conference papers on the topic "A transdermal therapeutic system"

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N, Midhun Dinesh, Rubi P, Asna Saniya, and Kamalraj S. "IoMT-Based Parkinson Therapeutic System." In 2024 9th International Conference on Communication and Electronics Systems (ICCES). IEEE, 2024. https://doi.org/10.1109/icces63552.2024.10859602.

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Kini, Vrinda, Pooja Nag, and Kapil Sadani. "Sensors for therapeutic drug monitoring for ciprofloxacin." In 2024 Control Instrumentation System Conference (CISCON). IEEE, 2024. http://dx.doi.org/10.1109/ciscon62171.2024.10696606.

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Dikyol, Ömer, Elif Tuğçe Çil, and Tacha Serif. "Enhanced Therapeutic Engagement: A Gamified Arduino Glove System for Hand Rehabilitation." In 2024 Innovations in Intelligent Systems and Applications Conference (ASYU). IEEE, 2024. https://doi.org/10.1109/asyu62119.2024.10757096.

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Uchizono, T. "Enhancement of Permeation in Transdermal Drug Delivery System by 6μm Wavelength Area Using an MIR-FEL". У 4TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND. AIP, 2005. http://dx.doi.org/10.1063/1.1901613.

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Park, E. J. "Noninvasive Ultrasound Transdermal Insulin Delivery and Glucose Monitoring Using a Low-Profile Cymbal Array." In THERAPEUTIC ULTRASOUND: 5th International Symposium on Therapeutic Ultrasound. AIP, 2006. http://dx.doi.org/10.1063/1.2205535.

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Park, Eun-Joo, Jeff Dodds, Nadine Barrie Smith, Kullervo Hynynen, and Jacques Souquet. "Dose comparison of ultrasonic transdermal insulin delivery to subcutaneous insulin injection." In 9TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND: ISTU—2009. AIP, 2010. http://dx.doi.org/10.1063/1.3367167.

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NASTI, IVANA, VERA LA FERRARA, GABRIELLA RAMETTA, and GIROLAMO DI FRANCIA. "SILICON BASED TRANSDERMAL DRUG DELIVERY SYSTEM." In Proceedings of the 12th Italian Conference. WORLD SCIENTIFIC, 2008. http://dx.doi.org/10.1142/9789812833594_0049.

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Miyano, T., T. Miyachi, T. Okanishi, et al. "Hydrolyticmicroneedles as Transdermal Drug Delivery System." In TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference. IEEE, 2007. http://dx.doi.org/10.1109/sensor.2007.4300141.

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Uzunovic, A., S. Pilipovic, A. Sapcanin, and Z. Ademovic. "Evaluation of transdermal drug-delivery system of capsaicin." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608515.

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Yu, H. X., D. C. Li, R. C. Roberts, W. S. Liang, K. X. Xu, and N. C. Tien. "An integrated microfluidic system for interstitial fluid transdermal extraction." In TRANSDUCERS 2011 - 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference. IEEE, 2011. http://dx.doi.org/10.1109/transducers.2011.5969387.

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Reports on the topic "A transdermal therapeutic system"

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Sirivat, Anuvat. Electrically controlled release of drugs from alginate hydrogels for transdermal drug delivery application. Chulalongkorn University, 2014. https://doi.org/10.58837/chula.res.2014.80.

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A drug-loaded conductive polymer/hydrogel blend, benzoic acid-loaded poly(3,4-ethylenedioxythiophene/alginate (BA-loaded PEDOT/Alg) hydrogel, was used as a carrier/matrix for an electrical stimuli transdermal drug delivery system (TDDS). The effects of crosslinking ratio, PEDOT particle size, and electric field strength on the release mechanism and the diffusion coefficient (D) of BA were examined by using a modified Franz-diffusion cell. The diffusion scaling exponent value of BA is close to 0.5 which refers to the diffusion controlled mechanism, or the Fickian diffusion as the BA release mec
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Zhong, Lin, Anqing Lu, Xiyue Lu, et al. Molecular mechanisms and therapeutic prospects of immunotherapy and targeted therapy in primary central nervous system lymphoma. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2024. https://doi.org/10.37766/inplasy2024.12.0103.

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Coelho Resende, Noelle, Renata Weber, Jardel Fischer Loeck, et al. Working Paper Series: Therapeutic Communities in Brazil. Edited by Taniele Rui and Fiore Mauricio. Drugs, Security and Democracy Program, Social Science Research Council, 2021. http://dx.doi.org/10.35650/ssrc.2081.d.2021.

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Spread across Brazil and attaining an unparalleled political force, therapeutic communities are as inescapable in the debate on drug policy as they are complex to define. Although they are not a Brazilian creation, they have been operating in that country for decades, and their dissemination intensified in the 1990s. In 2011, they were officially incorporated into Brazil's Psychosocial Care Network (Rede de Atenção Psicossocial, or RAPS). Since then, therapeutic communities have been at the center of public debates about their regulation; about how they should—or even if they should—be a part
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Dong, Chunke, Di Wu, Yingna Qi, Hongyu Wei, and Chungen Li. Therapeutic efficacy of third-generation percutaneous vertebral augmentation system in osteoporotic vertebral compression fractures: a systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2021. http://dx.doi.org/10.37766/inplasy2021.1.0015.

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Basu, Sayani. Nanoparticle-Based Therapeutics for the Treatment of Stroke. Nature Library Ltd, 2020. http://dx.doi.org/10.47496/nl.blog.13.

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Takeda, Mamoru. Neurophysiological Mechanisms Underlying the Attenuation of Nociceptive and Pathological Pain by Phytochemicals: Clinical Application as Therapeutic Agents. Progress in Neurobiology, 2024. http://dx.doi.org/10.60124/j.pneuro.2024.10.02.

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Although phytochemicals are plant-derived toxins that are primarily produced by plants as a form of defense against insects or microbes, several lines of studies have demonstrated that phytochemicals (e.g., polyphenols, carotenoids, and amino acids) have several beneficial biological actions for human health, such as anti-oxidative, anti-inflammatory, and cardioprotective effects. Recent studies have demonstrated that phytochemicals can modulate neuronal excitability in the nervous system, including nociceptive sensory transmission, so it is possible that phytochemicals could be complementary
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Kolesova, N. A. Educational and methodological manual for teachers of preschool educational organizations "Elements of fairy-tale therapy in the socio-communicative development of older preschool children". Sib-expertise, 2022. http://dx.doi.org/10.12731/er0532.03022022.

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The textbook emphasizes the relevance of the problem of the socio-communicative development of children of older preschool age. The manual consists of two chapters: the first chapter reveals general approaches and features of using elements of fairy-tale therapy in working with children of older preschool age to form their socio-personal competencies, describes the features of perceptions of preschool-age children when reading tales into their hearing, and also reveals the use of elements of fairy-tale therapy in pedagogical measures for the socio-communicative and speech development of older
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Wang, Xiaoyu. Pediatric tuina in treating recurrent respiratory tract infection in children: a systematic review and meta‑analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, 2023. http://dx.doi.org/10.37766/inplasy2023.4.0075.

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Review question / Objective: Is pediatric tuina an effective treatment for recurrent respiratory tract infection in children? Condition being studied: Recurrent respiratory tract infection (RRTI) is a common disease in children, which refers to the recurrence of upper and lower respiratory tract infections within a year, exceeding the prescribed number of times. It is more common in infants under 3 years old. The disease is easy to relapse and lasts for a long time, affecting the normal growth and development of children and physical and mental health, easily causing other diseases, leading to
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Quak, Evert-jan. Lessons Learned from Community-based Management of Acute Malnutrition (CMAM) Programmes that Operate in Fragile or Conflict Affected Settings. Institute of Development Studies (IDS), 2021. http://dx.doi.org/10.19088/k4d.2021.133.

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This rapid review synthesises the literature on how community-based management of acute malnutrition (CMAM) programmes could be adapted in settings of conflict and fragility. It identifies multiple factors affecting the quality and effectiveness of CMAM services including the health system, community engagement and linkages with other programmes, including education, sanitation, and early childhood development. Family MUAC (Mid-Upper Arm Circumference) is a useful tool to increase community participation and detect early cases of moderate acute malnutrition (MAM) and severe acute malnutrition
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Goel, Dr Divanshu, and Dr Manjeet Singh. HYBRID EXTERNAL FIXATION FOR PROXIMAL TIBIAL FRACTURES. World Wide Journals, 2023. http://dx.doi.org/10.36106/ijar/1505336.

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Abstract:
Introduction: Intraarticular fractures of the tibial plateau and periarticular fractures of the proximal tibia, caused by high energy trauma pose a therapeutic dilemma. Such fractures are associated with extensive soft tissue damage with or without compound injury. The management of such high velocity injuries become a challenge to the trauma surgeons. The goals of these periarticular fractures management are 1. Restoration of joint congruity by anatomic reduction 2. Stable xation of fractures thus allowing early movements 3. Proper care of injured soft tissues. In earlier days uniplanar exte
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