Log in

Relevant bibliographies by topics / A2KS / Journal articles

To see the other types of publications on this topic, follow the link: A2KS.

Journal articles on the topic 'A2KS'

Author: Grafiati

Published: 4 June 2021

Last updated: 7 February 2022

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'A2KS.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Liu, Ning, Yinghua Jiang, Joon Yong Chung, et al. "Annexin A2 Deficiency Exacerbates Neuroinflammation and Long-Term Neurological Deficits after Traumatic Brain Injury in Mice." International Journal of Molecular Sciences 20, no. 24 (2019): 6125. http://dx.doi.org/10.3390/ijms20246125.

Full text

Abstract:

Our laboratory and others previously showed that Annexin A2 knockout (A2KO) mice had impaired blood–brain barrier (BBB) development and elevated pro-inflammatory response in macrophages, implying that Annexin A2 (AnxA2) might be one of the key endogenous factors for maintaining homeostasis of the neurovascular unit in the brain. Traumatic brain injury (TBI) is an important cause of disability and mortality worldwide, and neurovascular inflammation plays an important role in the TBI pathophysiology. In the present study, we aimed to test the hypothesis that A2KO promotes pro-inflammatory response in the brain and worsens neurobehavioral outcomes after TBI. TBI was conducted by a controlled cortical impact (CCI) device in mice. Our experimental results showed AnxA2 expression was significantly up-regulated in response to TBI at day three post-TBI. We also found more production of pro-inflammatory cytokines in the A2KO mouse brain, while there was a significant increase of inflammatory adhesion molecules mRNA expression in isolated cerebral micro-vessels of A2KO mice compared with wild-type (WT) mice. Consistently, the A2KO mice brains had a significant increase in leukocyte brain infiltration at two days after TBI. Importantly, A2KO mice had significantly worse sensorimotor and cognitive function deficits up to 28 days after TBI and significantly larger brain tissue loss. Therefore, these results suggested that AnxA2 deficiency results in exacerbated early neurovascular pro-inflammation, which leads to a worse long-term neurologic outcome after TBI.

APA, Harvard, Vancouver, ISO, and other styles

2

Tomaszewski, Waldemar, Vladimir Gun’ko, Roman Leboda, and Jadwiga Skubiszewska-Zięba. "Interaction of methoxy- and methylenedioxyamphetamines with carbon and polymeric adsorbents in polar liquids." Open Chemistry 8, no. 4 (2010): 750–57. http://dx.doi.org/10.2478/s11532-010-0042-y.

Full text

Abstract:

AbstractSolid phase extraction (SPE) of methoxy- and methylenedioxyamphetamines from diluted aqueous solutions was investigated on carbon and polymeric adsorbents of different textures and chemical compositions. Those adsorbents were applied cartridges packed with three chemically modified carbons prepared from plum stones (initial A2PS, oxidized A2PS-O, and reduced A2PS-H) and commercially available adsorbents (polymeric LiChrolut EN, graphitized Hypercarb and Carboprep). Several factors influence the recovery rates of amphetamine derivatives such as the polarity of adsorbates (free energy of salvation), the specific surface area and surface composition of adsorbents, and the solvent characteristics. Different combinations of these factors affect the recovery rate (R1) for high- and low-surface area adsorbents. The minimal R1 values are observed for an amphetamine derivative at a maximal solvation effect and for a set of amphetamines adsorbed on graphitized carbons.

APA, Harvard, Vancouver, ISO, and other styles

3

Yates, P. J., R. Hazen, M. St. Clair, L. Boone, M. Tisdale, and R. C. Elston. "In Vitro Development of Resistance to Human Immunodeficiency Virus Protease Inhibitor GW640385." Antimicrobial Agents and Chemotherapy 50, no. 3 (2006): 1092–95. http://dx.doi.org/10.1128/aac.50.3.1092-1095.2006.

Full text

Abstract:

ABSTRACT Development of in vitro resistance to GW640385, a new human immunodeficiency virus type 1 protease inhibitor, was studied. Variants characterized included one with <4-fold resistance and amino acid substitutions Q58E/A71V (protease) and P452K (Gag) and one with >50-fold resistance and amino acid substitutions L10F/G16E/E21K/A28S/M46I/F53L/A71V (protease) and L449F/P453T (Gag). The A28S substitution substantially reduced replication capacity.

APA, Harvard, Vancouver, ISO, and other styles

4

de Almeida, Pedro. "Generating APL printouts with a2ps." ACM SIGAPL APL Quote Quad 35, no. 3 (2007): 18–23. http://dx.doi.org/10.1145/1286361.1286363.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Knopf, Alison. "Stimulants for preschool ADHD down, A2As up." Alcoholism & Drug Abuse Weekly 32, no. 37 (2020): 4–5. http://dx.doi.org/10.1002/adaw.32841.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Xie, Jingli, Zhiguo Luo, and Guoping Chen. "Homoclinic Solutions for a Class of the Second-Order Impulsive Hamiltonian Systems." Abstract and Applied Analysis 2013 (2013): 1–8. http://dx.doi.org/10.1155/2013/583107.

Full text

Abstract:

This paper is concerned with the existence of homoclinic solutions for a class of the second order impulsive Hamiltonian systems. By employing the Mountain Pass Theorem, we demonstrate that the limit of a2kT-periodic approximation solution is a homoclinic solution of our problem.

APA, Harvard, Vancouver, ISO, and other styles

7

Nigam, Santosh, and Tankred Schewe. "Phospholipase A2s and lipid peroxidation." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1488, no. 1-2 (2000): 167–81. http://dx.doi.org/10.1016/s1388-1981(00)00119-0.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Paisansathan, Chanannait, Haoliang Xu, Francesco Vetri, Moises Hernandez, and Dale A. Pelligrino. "Interactions between adenosine and K+ channel-related pathways in the coupling of somatosensory activation and pial arteriolar dilation." American Journal of Physiology-Heart and Circulatory Physiology 299, no. 6 (2010): H2009—H2017. http://dx.doi.org/10.1152/ajpheart.00702.2010.

Full text

Abstract:

Multiple, perhaps interactive, mechanisms participate in the linkage between increased neural activity and cerebral vasodilation. In the present study, we assessed whether neural activation-related pial arteriolar dilation (PAD) involved interactions among adenosine (Ado) A2 receptors (A2Rs), large-conductance Ca2+-operated K+ (BKCa) channels, and inward rectifier K+ (Kir) channels. In rats with closed cranial windows, we monitored sciatic nerve stimulation (SNS)-induced PAD in the absence or presence of pharmacological blockade of A2Rs (ZM-241385), ecto-5′-nucleotidase (α,β-methylene-adenosine diphosphate), BKCa channels (paxilline), and Kir channels (BaCl2). Individually, these interventions led to 53–66% reductions in SNS-induced PADs. Combined applications of these blockers led to little or no further repression of SNS-induced PADs, suggesting interactions among A2Rs and K+ channels. In the absence of SNS, BaCl2 blockade of Kir channels produced 52–80% reductions in Ado and NS-1619 (BKCa channel activator)-induced PADs. In contrast, paxilline blockade of BKCa channels was without effect on dilations elicited by KCl (Kir channel activator) and Ado suffusions, indicating that Ado- and NS-1619-associated PADs involved Kir channels. In addition, targeted ablation of the superficial glia limitans was associated with a selective 60–80% loss of NS-1619 responses, suggesting that the BKCa channel participation (and paxilline sensitivity) derived largely from channels within the glia limitans. Additionally, blockade of either PKA or adenylyl cyclase caused markedly attenuated pial arteriolar responses to SNS and, in the absence of SNS, responses to Ado, KCl, and NS-1619. These findings suggested a key, possibly permissive, role for A2R-linked cAMP generation and PKA-induced K+ channel phosphorylation in somatosensory activation-evoked PAD.

APA, Harvard, Vancouver, ISO, and other styles

9

Gonzalez-Buritica, H., M. A. Khamashita, and G. R. Hughes. "Synovial fluid phospholipase A2s and inflammation." Annals of the Rheumatic Diseases 48, no. 4 (1989): 267–69. http://dx.doi.org/10.1136/ard.48.4.267.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Murakami, Makoto. "Novel functions of phospholipase A2s: Overview." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1864, no. 6 (2019): 763–65. http://dx.doi.org/10.1016/j.bbalip.2019.02.005.

Full text

APA, Harvard, Vancouver, ISO, and other styles

11

Ashton, Anthony W., Shankar Mukherjee, FNU Nagajyothi, et al. "Thromboxane A2is a key regulator of pathogenesis duringTrypanosoma cruziinfection." Journal of Cell Biology 177, no. 2 (2007): i4. http://dx.doi.org/10.1083/jcb1772oia4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

12

Knopf, Alison. "Preschoolers with ADHD medicated with stimulants decreasing, A2As increasing." Brown University Child and Adolescent Behavior Letter 36, no. 10 (2020): 5–6. http://dx.doi.org/10.1002/cbl.30495.

Full text

APA, Harvard, Vancouver, ISO, and other styles

13

REGELSON, W., and R. FRANSON. "Phospholipase A2as a "Death Trigger" in the Aging Process." Annals of the New York Academy of Sciences 621, no. 1 Physiological (1991): 262–76. http://dx.doi.org/10.1111/j.1749-6632.1991.tb16985.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

14

Chen, Xi, Xia Liu, Qiang Gan, Changgen Feng, and Qian Zhang. "Molecular Dynamics Simulations of A27S and K120A Mutated PTP1B Reveals Selective Binding of the Bidentate Inhibitor." BioMed Research International 2019 (January 8, 2019): 1–11. http://dx.doi.org/10.1155/2019/9852897.

Full text

Abstract:

Protein tyrosine phosphatase 1B (PTP1B) is considered a potential target for the treatment of type II diabetes and obesity due to its critical negative role in the insulin signaling pathway. However, improving the selectivity of PTP1B inhibitors over the most closely related T-cell protein tyrosine phosphatase (TCPTP) remains a major challenge for inhibitor development. Lys120 at the active site and Ser27 at the second pTyr binding site are distinct in PTP1B and TCPTP, which may bring differences in binding affinity. To explore the determinant of selective binding of inhibitor, molecular dynamics simulations with binding free energy calculations were performed on K120A and A27S mutated PTP1B, and the internal changes induced by mutations were investigated. Results reveal that the presence of Lys120 induces a conformational change in the WPD-loop and YRD-motif and has a certain effect on the selective binding at the active site. Ser27 weakens the stability of the inhibitor at the second pTyr binding site by altering the orientation of the Arg24 and Arg254 side chains via hydrogen bonds. Further comparison of alanine scanning demonstrates that the reduction in the energy contribution of Arg254 caused by A27S mutation leads to a different inhibitory activity. These observations provide novel insights into the selective binding mechanism of PTP1B inhibitors to TCPTP.

APA, Harvard, Vancouver, ISO, and other styles

15

Chávez, Vivian. "Language, Gender and Violence in Qualitative Research." International Quarterly of Community Health Education 21, no. 1 (2002): 3–18. http://dx.doi.org/10.2190/urht-a2kx-gk95-aaa0.

Full text

Abstract:

The purpose of this exploratory study is to provide a deep understanding of young women's personal accounts of violence to inform prevention programs and policies. Individual and focus group interviews about everyday experiences with violence were conducted with 67 young women, ages 15–19, at a high school in San Francisco, California. Qualitative methods were used to assess the range of young women's experiences with community and interpersonal violence. Three themes emerged from the data: 1) witnessing dating violence; 2) emotions and the language of the body; and 3) the paradox of love and violence. Violence in the lives of young women challenges assumptions about what “youth violence” means, how it happens, and who it happens to.

APA, Harvard, Vancouver, ISO, and other styles

16

Richter, Holly E., Robert L. Holley, Shambhavi Chandraiah, and R. Edward Varner. "Laparoscopic and Psychologic Evaluation of Women with Chronic Pelvic Pain." International Journal of Psychiatry in Medicine 28, no. 2 (1998): 243–53. http://dx.doi.org/10.2190/a2k2-g7j5-mnbq-bnde.

Full text

Abstract:

Objective: Pelvic pain can account for up to 40 percent of laparoscopies performed by gynecologists. This report compares the psychological profiles and efficacy of laparoscopic surgery at long-term follow-up in a series of laparoscopy-positive and laparoscopy-negative patients with chronic pelvic pain. Method: A retrospective chart review was performed on patients diagnosed with chronic pelvic pain combined with postoperative written questionnaires and self-rating scales. These questionnaires were used to assess long-term post laparoscopy follow-up of the physical and psychological status of women with positive findings at laparoscopy compared to those women with negative findings. Results: There were no statistically significant demographic differences between respondents and nonrespondents. In the respondents, no statistically significant differences were noted even with long-term follow-up when comparing responses of the laparoscopy-positive and laparoscopy-negative groups on the above questionnaires. Conclusion: Though reporting modest improvement in pelvic pain since laparoscopy, both groups reported a high incidence of anxiety, depression, physical worries, and marital/sexual problems.

APA, Harvard, Vancouver, ISO, and other styles

17

Townsend, Peter. "Evading the Issue of Widening Inequalities of Health in Britain: A Reply to Rudolf Klein." International Journal of Health Services 21, no. 1 (1991): 183–86. http://dx.doi.org/10.2190/cjfa-yxwv-qe4d-a2k7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

18

Suckling, Keith. "Phospholipase A2s: Developing drug targets for atherosclerosis." Atherosclerosis 212, no. 2 (2010): 357–66. http://dx.doi.org/10.1016/j.atherosclerosis.2010.03.011.

Full text

APA, Harvard, Vancouver, ISO, and other styles

19

Winget, Jason M., Ying H. Pan, and Brian J. Bahnson. "The interfacial binding surface of phospholipase A2s." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1761, no. 11 (2006): 1260–69. http://dx.doi.org/10.1016/j.bbalip.2006.08.002.

Full text

APA, Harvard, Vancouver, ISO, and other styles

20

Sheridan, Alice M., Adam Sapirstein, Nicole Lemieux, Brennan D. Martin, Dae Kyong Kim, and Joseph V. Bonventre. "Nuclear Translocation of Cytosolic Phospholipase A2Is Induced by ATP Depletion." Journal of Biological Chemistry 276, no. 32 (2001): 29899–905. http://dx.doi.org/10.1074/jbc.m103758200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

21

Mukhopadhyay, Amitabha, and Philip Stahl. "Bee Venom Phospholipase A2Is Recognized by the Macrophage Mannose Receptor." Archives of Biochemistry and Biophysics 324, no. 1 (1995): 78–84. http://dx.doi.org/10.1006/abbi.1995.9926.

Full text

APA, Harvard, Vancouver, ISO, and other styles

22

Blanpain, Cédric, Benhur Lee, Marie Tackoen, et al. "Multiple nonfunctional alleles of CCR5 are frequent in various human populations." Blood 96, no. 5 (2000): 1638–45. http://dx.doi.org/10.1182/blood.v96.5.1638.

Full text

Abstract:

Abstract CCR5 is the major coreceptor for macrophage-tropic strains of the human immunodeficiency virus type I (HIV-1). Homozygotes for a 32-base pair (bp) deletion in the coding sequence of the receptor (CCR5Δ32) were found to be highly resistant to viral infection, and CCR5 became, therefore, one of the paradigms illustrating the influence of genetic variability onto individual susceptibility to infectious and other diseases. We investigated the functional consequences of 16 other natural CCR5 mutations described in various human populations. We found that 10 of these variants are efficiently expressed at the cell surface, bind [125I]-MIP-1β with affinities similar to wtCCR5, respond functionally to chemokines, and act as HIV-1 coreceptors. In addition to Δ32, six mutations were characterized by major alterations in their functional response to chemokines, as a consequence of intracellular trapping and poor expression at the cell surface (C101X, FS299), general or specific alteration of ligand binding affinities (C20S, C178R, A29S), or relative inability to mediate receptor activation (L55Q). A29S displayed an unusual pharmacological profile, binding and responding to MCP-2 similarly to wtCCR5, but exhibiting severely impaired binding and functional responses to MIP-1α, MIP-1β, and RANTES. In addition to Δ32, only C101X was totally unable to mediate entry of HIV-1. The fact that nonfunctional CCR5 alleles are relatively frequent in various human populations reinforces the hypothesis of a selective pressure favoring these alleles.

APA, Harvard, Vancouver, ISO, and other styles

23

Blanpain, Cédric, Benhur Lee, Marie Tackoen, et al. "Multiple nonfunctional alleles of CCR5 are frequent in various human populations." Blood 96, no. 5 (2000): 1638–45. http://dx.doi.org/10.1182/blood.v96.5.1638.h8001638_1638_1645.

Full text

Abstract:

CCR5 is the major coreceptor for macrophage-tropic strains of the human immunodeficiency virus type I (HIV-1). Homozygotes for a 32-base pair (bp) deletion in the coding sequence of the receptor (CCR5Δ32) were found to be highly resistant to viral infection, and CCR5 became, therefore, one of the paradigms illustrating the influence of genetic variability onto individual susceptibility to infectious and other diseases. We investigated the functional consequences of 16 other natural CCR5 mutations described in various human populations. We found that 10 of these variants are efficiently expressed at the cell surface, bind [125I]-MIP-1β with affinities similar to wtCCR5, respond functionally to chemokines, and act as HIV-1 coreceptors. In addition to Δ32, six mutations were characterized by major alterations in their functional response to chemokines, as a consequence of intracellular trapping and poor expression at the cell surface (C101X, FS299), general or specific alteration of ligand binding affinities (C20S, C178R, A29S), or relative inability to mediate receptor activation (L55Q). A29S displayed an unusual pharmacological profile, binding and responding to MCP-2 similarly to wtCCR5, but exhibiting severely impaired binding and functional responses to MIP-1α, MIP-1β, and RANTES. In addition to Δ32, only C101X was totally unable to mediate entry of HIV-1. The fact that nonfunctional CCR5 alleles are relatively frequent in various human populations reinforces the hypothesis of a selective pressure favoring these alleles.

APA, Harvard, Vancouver, ISO, and other styles

24

Packard, Chris J., Denis S. J. O'Reilly, Muriel J. Caslake, et al. "Lipoprotein-Associated Phospholipase A2as an Independent Predictor of Coronary Heart Disease." New England Journal of Medicine 343, no. 16 (2000): 1148–55. http://dx.doi.org/10.1056/nejm200010193431603.

Full text

APA, Harvard, Vancouver, ISO, and other styles

25

Kudo, Ichiro. "Phospholipase A2s which provide arachidonates for eicosanoid generation." Ensho 14, no. 6 (1994): 455–65. http://dx.doi.org/10.2492/jsir1981.14.455.

Full text

APA, Harvard, Vancouver, ISO, and other styles

26

Krikorian, Gaëlle. "A2K, un mouvement international pour l'accès aux savoirs." Multitudes 46, no. 3 (2011): 103. http://dx.doi.org/10.3917/mult.046.0103.

Full text

APA, Harvard, Vancouver, ISO, and other styles

27

Hadfield, Amelia, and Andrej J. Zwitter. "Open Access Publishing." Politics and Governance 1, no. 2 (2013): 102–3. http://dx.doi.org/10.17645/pag.v1i2.100.

Full text

Abstract:

The rise of open source online journals, free online courses, and other changes in the research and education environment, coined the "academic spring" by some commentators, represents an increasing trend in opening up the rules of access for research. Universities, libraries, publishers and even governments are paying attention to this new movement often referred to with the acronym A2K (access to knowledge).

APA, Harvard, Vancouver, ISO, and other styles

28

Smani, Tarik, Sergey I. Zakharov, Endri Leno, Peter Csutora, Elena S. Trepakova, and Victoria M. Bolotina. "Ca2+-independent Phospholipase A2Is a Novel Determinant of Store-operated Ca2+Entry." Journal of Biological Chemistry 278, no. 14 (2003): 11909–15. http://dx.doi.org/10.1074/jbc.m210878200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

29

Shohami, E., Y. Shapira, G. Yadid, N. Reisfeld, and S. Yedgar. "Brain Phospholipase A2Is Activated After Experimental Closed Head Injury in the Rat." Journal of Neurochemistry 53, no. 5 (1989): 1541–46. http://dx.doi.org/10.1111/j.1471-4159.1989.tb08550.x.

Full text

APA, Harvard, Vancouver, ISO, and other styles

30

Murakami, Makoto, Yoshihito Nakatani, Hiroshi Kuwata, and Ichiro Kudo. "Cellular components that functionally interact with signaling phospholipase A2s." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1488, no. 1-2 (2000): 159–66. http://dx.doi.org/10.1016/s1388-1981(00)00118-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

31

Kimura-Matsumoto, Masayo, Yukio Ishikawa, Kazuo Komiyama, et al. "Expression of secretory phospholipase A2s in human atherosclerosis development." Atherosclerosis 196, no. 1 (2008): 81–91. http://dx.doi.org/10.1016/j.atherosclerosis.2006.08.062.

Full text

APA, Harvard, Vancouver, ISO, and other styles

32

Murakami, Makoto, Yoshimi Miki, Hiroyasu Sato, Remi Murase, Yoshitaka Taketomi, and Kei Yamamoto. "Group IID, IIE, IIF and III secreted phospholipase A2s." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1864, no. 6 (2019): 803–18. http://dx.doi.org/10.1016/j.bbalip.2018.08.014.

Full text

APA, Harvard, Vancouver, ISO, and other styles

33

Kita, Yoshihiro, Takayo Ohto, Naonori Uozumi, and Takao Shimizu. "Biochemical properties and pathophysiological roles of cytosolic phospholipase A2s." Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1761, no. 11 (2006): 1317–22. http://dx.doi.org/10.1016/j.bbalip.2006.08.001.

Full text

APA, Harvard, Vancouver, ISO, and other styles

34

Zhou, Shiyuan, and Yinglin Wang. "Clustering Services Based on Community Detection in Service Networks." Mathematical Problems in Engineering 2019 (December 2, 2019): 1–11. http://dx.doi.org/10.1155/2019/1495676.

Full text

Abstract:

Service-oriented computing has become a promising way to develop software by composing existing services on the Internet. However, with the increasing number of services on the Internet, how to match requirements and services becomes a difficult problem. Service clustering has been regarded as one of the effective ways to improve service matching. Related work shows that structure-related similarity metrics perform better than semantic-related similarity metrics in clustering services. Therefore, it is of great importance to propose much more useful structure-related similarity metrics to improve the performance of service clustering approaches. However, in the existing work, this kind of work is very rare. In this paper, we propose a SCAS (service clustering approach using structural metrics) to group services into different clusters. SCAS proposes a novel metric A2S (atomic service similarity) to characterize the atomic service similarity as a whole, which is a linear combination of C2S (composite-sharing similarity) and A3S (atomic-service-sharing similarity). Then, SCAS applies a guided community detection algorithm to group atomic services into clusters. Experimental results on a real-world data set show that our SCAS performs better than the existing approaches. Our A2S metric is promising in improving the performance of service clustering approaches.

APA, Harvard, Vancouver, ISO, and other styles

35

Yang, Eric H., Joseph P. McConnell, Ryan J. Lennon, et al. "Lipoprotein-Associated Phospholipase A2Is an Independent Marker for Coronary Endothelial Dysfunction in Humans." Arteriosclerosis, Thrombosis, and Vascular Biology 26, no. 1 (2006): 106–11. http://dx.doi.org/10.1161/01.atv.0000191655.87296.ab.

Full text

APA, Harvard, Vancouver, ISO, and other styles

36

Denson, Donald D., Xiaoping Wang, Roger T. Worrell, Otor AlKhalili, and Douglas C. Eaton. "Cytosolic Phospholipase A2Is Required for Optimal ATP Activation of BK Channels in GH3Cells." Journal of Biological Chemistry 276, no. 10 (2000): 7136–42. http://dx.doi.org/10.1074/jbc.m009566200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

37

Chan, Clarissa. "A2As or stimulants: which is better for treatment of ADHD in young children?" Pharmacy Today 27, no. 8 (2021): 25. http://dx.doi.org/10.1016/j.ptdy.2021.07.010.

Full text

APA, Harvard, Vancouver, ISO, and other styles

38

Irawan, Jimmy, Bobby Oedy P. Soepangkat, and Sony Sunaryo. "ANALISIS KUALITAS LAYANAN DAN KEPUASAN PELANGGAN DI BENGKEL TOYOTA-A2K." Jurnal Teknobisnis 2, no. 1 (2017): 33. http://dx.doi.org/10.12962/j24609463.v2i1.2816.

Full text

APA, Harvard, Vancouver, ISO, and other styles

39

Degousee, Norbert, Farideh Ghomashchi, Eva Stefanski, et al. "Groups IV, V, and X Phospholipases A2s in Human Neutrophils." Journal of Biological Chemistry 277, no. 7 (2001): 5061–73. http://dx.doi.org/10.1074/jbc.m109083200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

40

Xiao, Zhifeng, Kai Wang, Qiao Wan, Xiaowei Tan, Chuan Xu, and Fanfan Xia. "A2S-Det: Efficiency Anchor Matching in Aerial Image Oriented Object Detection." Remote Sensing 13, no. 1 (2020): 73. http://dx.doi.org/10.3390/rs13010073.

Full text

Abstract:

Object detection is a challenging task in aerial images, where many objects have large aspect ratios and are densely arranged. Most anchor-based rotating detectors assign anchors for ground-truth objects by a fixed restriction of the rotation Intersection-over-Unit (IoU) between anchors and objects, which directly follow horizontal detectors. Due to many directional objects with a large aspect ratio, the object-anchor IoU is heavily influenced by the angle, which may cause few anchors assigned for some ground-truth objects. In this study, we propose an anchor selection method based on sample balance assigning anchors adaptively, which we name the Self-Adaptive Anchor Selection (A2S-Det) method. For each ground-truth object, A2S-Det selects a set of candidate anchors by horizontal IoU. Then, an adaptive threshold module is adopted on the set of candidate anchors, which calculates a boundary of these candidate anchors aiming to keep a balance between positive and negative anchors. In addition, we propose a coordinate regression of relative reference (CR3) module to precisely regress the rotating bounding box. We test our method on a public aerial image dataset, and prove better performance than many other one-stage detectors and two-stage detectors, achieving the mAP of 70.64. An efficiency anchor matching method helps the detector achieve better performance for objects with large aspect ratios.

APA, Harvard, Vancouver, ISO, and other styles

41

Rodríguez, Juan P., Elbio Leiguez, Carlos Guijas та ін. "A Lipidomic Perspective of the Action of Group IIA Secreted Phospholipase A2 on Human Monocytes: Lipid Droplet Biogenesis and Activation of Cytosolic Phospholipase A2α". Biomolecules 10, № 6 (2020): 891. http://dx.doi.org/10.3390/biom10060891.

Full text

Abstract:

Phospholipase A2s constitute a wide group of lipid-modifying enzymes which display a variety of functions in innate immune responses. In this work, we utilized mass spectrometry-based lipidomic approaches to investigate the action of Asp-49 Ca2+-dependent secreted phospholipase A2 (sPLA2) (MT-III) and Lys-49 sPLA2 (MT-II), two group IIA phospholipase A2s isolated from the venom of the snake Bothrops asper, on human peripheral blood monocytes. MT-III is catalytically active, whereas MT-II lacks enzyme activity. A large decrease in the fatty acid content of membrane phospholipids was detected in MT III-treated monocytes. The significant diminution of the cellular content of phospholipid-bound arachidonic acid seemed to be mediated, in part, by the activation of the endogenous group IVA cytosolic phospholipase A2α. MT-III triggered the formation of triacylglycerol and cholesterol enriched in palmitic, stearic, and oleic acids, but not arachidonic acid, along with an increase in lipid droplet synthesis. Additionally, it was shown that the increased availability of arachidonic acid arising from phospholipid hydrolysis promoted abundant eicosanoid synthesis. The inactive form, MT-II, failed to produce any of the effects described above. These studies provide a complete lipidomic characterization of the monocyte response to snake venom group IIA phospholipase A2, and reveal significant connections among lipid droplet biogenesis, cell signaling and biochemical pathways that contribute to initiating the inflammatory response.

APA, Harvard, Vancouver, ISO, and other styles

42

Lichtenbergova, Lenka, Edward T. Yoon, and Wonhwa Cho. "Membrane Penetration of Cytosolic Phospholipase A2Is Necessary for Its Interfacial Catalysis and Arachidonate Specificity†." Biochemistry 37, no. 40 (1998): 14128–36. http://dx.doi.org/10.1021/bi980888s.

Full text

APA, Harvard, Vancouver, ISO, and other styles

43

Carnevale, Kevin A., and Martha K. Cathcart. "Calcium-Independent Phospholipase A2Is Required for Human Monocyte Chemotaxis to Monocyte Chemoattractant Protein 1." Journal of Immunology 167, no. 6 (2001): 3414–21. http://dx.doi.org/10.4049/jimmunol.167.6.3414.

Full text

APA, Harvard, Vancouver, ISO, and other styles

44

Westwood, Sara A., Philip J. Seaman, Peter J. Ablett, Isao Yuasa, Sebastian Weidinger, and Kazuo Umetsu. "A2HS*11: A new allele of alpha-2-HS-glycoprotein found in Afro-Caribbeans." Electrophoresis 8, no. 12 (1987): 559–61. http://dx.doi.org/10.1002/elps.1150081205.

Full text

APA, Harvard, Vancouver, ISO, and other styles

45

Jayadev, Supriya, Heather L. Hayter, Nathalie Andrieu та ін. "Phospholipase A2Is Necessary for Tumor Necrosis Factor α-induced Ceramide Generation in L929 Cells". Journal of Biological Chemistry 272, № 27 (1997): 17196–203. http://dx.doi.org/10.1074/jbc.272.27.17196.

Full text

APA, Harvard, Vancouver, ISO, and other styles

46

Agrawal, Sarita, and Swadesh Sahoo. "Radius of convexity of partial sums of odd functions in the close-to-convex family." Filomat 31, no. 11 (2017): 3519–29. http://dx.doi.org/10.2298/fil1711519a.

Full text

Abstract:

We consider the class of all analytic and locally univalent functions f of the form f(z)=z + ??,n=2 a2n-1z2n-1, ?z? < 1, satisfying the condition Re(1+zf''(z)/f'(z)) >-1/2. We show that every section s2n-1(z) = z+ ?n,k=2 a2k-1z2k-1, of f, is convex in the disk ?z? < ?2/3. We also prove that the radius ?2/3 is best possible, i.e. the number ?2/3 cannot be replaced by a larger one.

APA, Harvard, Vancouver, ISO, and other styles

47

Komori, Yumiko. "Structure-Activity Relationship of Phospholipase A2s Isolated from Vipera aspis Venom." International Journal of Biochemistry Research & Review 2, no. 2 (2012): 50–59. http://dx.doi.org/10.9734/ijbcrr/2012/1074.

Full text

APA, Harvard, Vancouver, ISO, and other styles

48

Ishizaki, Jun, Noriko Suzuki, Ken-ichi Higashino, et al. "Cloning and Characterization of Novel Mouse and Human Secretory Phospholipase A2s." Journal of Biological Chemistry 274, no. 35 (1999): 24973–79. http://dx.doi.org/10.1074/jbc.274.35.24973.

Full text

APA, Harvard, Vancouver, ISO, and other styles

49

Li-Stiles, Bangyan, and Susan M. Fischer. "Mechanism(s) of activation of secretory phospholipase A2s in mouse keratinocytes." Journal of Lipid Research 40, no. 9 (1999): 1701–8. http://dx.doi.org/10.1016/s0022-2275(20)33417-9.

Full text

APA, Harvard, Vancouver, ISO, and other styles

50

Ho, Ka-Kei, Alexandra A. Anderson, Erika Rosivatz, Eric W. F. Lam, Rüdiger Woscholski, and David J. Mann. "Identification of Cyclin A2as the Downstream Effector of the Nuclear Phosphatidylinositol 4,5-Bisphosphate Signaling Network." Journal of Biological Chemistry 283, no. 9 (2007): 5477–85. http://dx.doi.org/10.1074/jbc.m706623200.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!