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Journal articles on the topic 'AB 92'

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Published: 4 June 2021

Last updated: 9 February 2022

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1

Apisarnthanarak, Anucha, Kittiya Jantarathaneewat, Siriththin Chansirikarnjana, Nattapong Tidwong, and Linda Mundy. "2022. Antibiotic Prescribing Behavior Among Surgeon." Open Forum Infectious Diseases 6, Supplement_2 (October 2019): S679. http://dx.doi.org/10.1093/ofid/ofz360.1702.

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Abstract Background A comparative study was conducted to evaluate prescribed antibiotic (AB) use in surgical patients with the Transtheoretical Model of Behavior (TTM) and Theory of Planned Behavior (TPB). Methods A survey was conducted at Thammasat University Hospital from January 1 to 31, 2019. We evaluated the appropriateness of AB uses in the surgical department reported per the hospital’s Drug Use Evaluation (DUE) form. After review of the DUE, in-depth interviews were conducted to all prescribers to explore antibiotic prescribing behavior based on TTM vs. TPB, using a standardized data collection tool. Data collected included demographics, indications, appropriateness of AB uses, the individual prescriber’s behavior based on TTM and TPB. The five TTM stages of change were categorized precontemplation, contemplation, preparation, action, and maintenance. In TPB assessment, we evaluated attitude toward AB uses, subjective norm to AB uses behavior, and perceived behavior control of AB uses behavior. Results There were 92 AB uses from 64 prescribers; 70 (70/92; 76%) used antibiotics appropriately. The majority of AB uses (62/92; 67%) were for treatment of infections. The most common reasons for inappropriate AB uses included inappropriate AB choices for treatment and prophylaxis of SSIs (n = 11, 50%) and inappropriate duration (n = 8, 36%). Physicians categorized in higher stages of TTM (action and maintenance) were strongly correlated with appropriate AB uses, while there was no correlation between the total TPB score and appropriateness of AB uses. By multivariate analysis, the TTM action and maintenance (aOR = 7.95; P = 0.02) and self-reported prescribers who considered patients as first priority (aOR = 4.02; P = 0.04) were associated with appropriate AB uses, while neurosurgical procedures (aOR = 0.13; P = 0.003) and antibiotic prescriptions for surgical prophylaxis (aOR = 0.15; P = 0.04) were associated with inappropriate AB uses. Conclusion Antibiotic prescribers categorized by TTM stages strongly correlated with appropriate AB uses. Additional studies to assess appropriate AB prescribing behavior, based on TTM stages of change, offer an opportunity to optimize surgical care. Disclosures All authors: No reported disclosures.

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Thomas, Mari R., James T. Crawley, Samuel J. Machin, and Marie Scully. "Domain Specificity and Mechanism of Action of Anti-ADAMTS13 Antibodies at Presentation and Relapse in Acquired Thrombotic Thrombocytopenic Purpura (TTP)." Blood 124, no. 21 (December 6, 2014): 468. http://dx.doi.org/10.1182/blood.v124.21.468.468.

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Abstract Acquired thrombotic thrombocytopenic purpura (TTP) is an autoimmune disease due to autoantibodies (Auto-Ab) against ADAMTS13, resulting in a severe deficiency in enzyme activity (<10%). Little is known about the pathogenicity of anti-ADAMTS13 IgG directed against different domains of the enzyme, or how domain specificity alters between presentation, remission or TTP relapse. We developed novel assays to explore domain specificity and inhibitory potential of anti-ADAMTS13 IgG using samples from the UK TTP Registry. Full-length ADAMTS13 and ADAMTS13 fragments (MD, MDTC and MDTCS - N-terminal domains; TSR2-8 and CUB1/2 - C-terminal domains) were expressed in HEK293T cells and purified. Microtitre plates were coated with ADAMTS13 or ADAMTS13 fragments, incubated with TTP plasmas and bound IgG detected. Domain specificity was further analysed by preincubation of patient samples with ADAMTS13 fragments, assessing the ability of fragments to compete for full-length ADAMTS13 binding on the plate. From a cohort of 92 acquired TTP patients at presentation, 100% (92/92) contained auto-Ab that recognised ADAMTS13 N-terminal domains (MDTCS). Of these, 39% (36/92) had auto-Ab recognising the N-terminal domains alone, 22% (20/92) also had anti-TSR2-8, and 39% (36/92) had anti-CUB1/2 auto-Abs. There was no correlation between auto-Ab domain specificity and mortality/disease severity (anti-ADAMTS13 IgG titre, plasma exchanges to remission, platelet count and cardiac involvement). There was no evidence for auto-Ab recognising MD or MDTC domains in 25 patients tested, suggesting immunoreactivity for MDTCS was primarily mediated through the spacer domain. Consistent with this, TTP IgG inhibited proteolysis of VWF115 (a recombinant VWF A2 domain fragment), but failed to inhibit VWF106 proteolysis (VWF A2 domain fragment lacking the spacer domain binding exosite). To examine the inhibitory potency of anti-ADAMTS13 auto-Ab, IgG isolated from TTP patient samples were titrated in reactions measuring MDTCS-mediated proteolysis of FRETS-VWF73. Twenty eight out of 43 presentation samples tested had inhibitory IgG (IC50 ranging from <0.2-5μM total IgG). Addition of excess of MDTC to 19/19 of these samples did not alter the IC50, confirming inhibition in these samples is mediated solely by anti-spacer antibodies. Intriguingly, 15/43 patients had no evidence of inhibitory auto-Ab, suggesting the pathogenic mechanism in these cases may be enhanced clearance of ADAMTS13. We therefore determined ADAMTS13 antigen concentrations by ELISA. All patients at presentation exhibited markedly reduced ADAMTS13 antigen levels (n=91, median 58ng/ml (range 0-450) vs. normal n=67, median 951ng/ml (515-1829); p<0.0001). Interestingly, patients with predominantly C terminal auto-Ab and no evidence of inhibitory auto-Ab had significantly lower ADAMTS13 antigen levels at first presentation than the rest of the cohort (median 2ng/ml (0-141) vs. 57ng/ml (0-356); p=0.006). Cases where rituximab failed to normalise ADAMTS13 activity despite clinical remission were associated with the persistence of inhibitory anti-N-terminal auto-Ab. Two patients with persistently high anti-ADAMTS13 IgG but normal ADAMTS13 activity and antigen levels during remission had non-pathogenic anti-TSR2-8 antibodies that seemingly had no effect upon ADAMTS13 function or clearance. Nine out of 16 patients exhibited altered auto-Ab domain specificity upon relapse, with either loss or development of anti-C-terminal auto-Ab. In conclusion, from our functional studies ADAMTS13 inhibition appears to be mediated exclusively by anti-spacer antibodies, with no evidence for the presence of auto-Ab that recognise/inhibit other N terminal domains. Importantly, we demonstrate ADAMTS13 antigen depletion is a crucial pathogenic mechanism in acquired TTP, accounting for a large proportion of the reduced ADAMTS13 activity detected in patient samples. Our results suggest that auto-Ab directed against the C-terminal domains of ADAMTS13 may be particularly important in mediating this clearance. There is continual development of the autoimmune response during treatment of TTP patients that can result in altered domain specificity at relapse. Disclosures No relevant conflicts of interest to declare.

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McDevitt, Pamela W., Rachel Fichtner, and James Norman Frame. "Rituximab (R) for the Treatment of Autoimmune Hemolytic Anemia (AIHA) in Adults: An Analysis of Literature Reports in 92 Patients." Blood 104, no. 11 (November 16, 2004): 3721. http://dx.doi.org/10.1182/blood.v104.11.3721.3721.

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Abstract R is an anti-CD20 MoAb developed to treat B-cell malignancies. While R has been used to treat various autoimmune disorders including AIHA, a systematic review of reports of R to treat AIHA in adults has not been performed. We describe the clinical features and response to R in patients (pts)18 yrs or > with AIHA from PubMed English language citations and manufacturer (Genentech, Inc.) provided reports from 1998–2004. 39 reports (34 case reports, 5 case series) identified 92 pts (M 47, F 44, NS 1) with a mean age of 60.7 yr (range, 18–91). 1°/2° Warm (W) Ab, Cold (C) Ab (± associated disease), and mixed (C/W) AIHA was observed in 11/33, 46, and 2 pts, respectively. Associated disease included: lymphoproliferative (LPD)-(W: NHL 4, CLL 20; C: NHL 26, CLL 1, other 6; C/W: other 1), rheumatologic-(W:6), infectious-(W:2, C:1 with EBV); and other (W:3; C:2) disorders. Other baseline pre-R features included: mean Hgb 7.5 g/dl (range, 2.8–12); >45 pts with a Hgb < 10 g/dl; DAT (+): all W-AIHA; Cold Ab or agglutinin (+): all C-AIHA; both DAT/C Ab(+): C/W-AIHA; previously untreated 17%; prior splenectomy >11 patients; transfusion dependent 21%; and a mean of 2.6 (range, 1–8) prior immunosuppressive regimens. R was administered as 375 mg/m2 IV weekly X 4 in 83% and in other schedules (15%) for a mean of 3 doses (range, 2–8); cycle no. was not stated in 2% pts. R was administered alone in 52 pts and with IVIG 3, chemotherapy 13, or corticosteroids 27. The criteria for response to R included: CR [stable↑ Hgb by 2 or > g/dl or Hgb 12 or > g/dl and (−) W or C Ab or agglutinin, resolution of symptoms of anemia, transfusion independent]; PR (↑ Hgb by 2 or > g/dl or Hgb 10 or > g/dl but < 12 g/dl, and 50% ↓ in C Ab/agglutinin titers, + warm Ab, improvement in symptoms of anemia, transfusion independent); NR (failure to meet CR/PR). 83% were eligible for response determination: R monotherapy-CR 10, PR 22, NR 14; R+other regimen-CR 12, PR 10, NR 8. Pt. response by type of AIHA included: 1° W-Ab (CR 3, PR 1, NR 3), 2° W-Ab (CR 7, PR 14, NR 7), C-Ab ± associated disease (CR 11, PR 17, NR 12) and C/W (CR 1). In the total group, the Hgb increased a mean of 3.8 g/dl (range, −1.4–10.5). Hgb increased in CRs by 5.6 (range, 2.9–10.5), in PRs by 4.0 (0.7–8.1), and in NRs by 2.1(−1.4–9.5). The mean time to response/response duration among CR+PRs was 22 days (range, 5–120)/10.5 mo. (range, 1.5–42). Response duration was recorded as last f/u if the pt did not relapse. Re-treatment with R was reported in 17 pts after initial best reported response (1st cycle PR 14, NR 3) with R alone (9) or in combination with CTX + DEX (5), or IFN (3) achieving 12 PRs (R 5, R+C+D 5, R+IFN 2) and 5 NRs (R 4, R+IFN 1). Reported R toxicity (n): infusion-related (7), myalgia (1), pruritis (2) rash (1) Gr.4 WBC (2) hypotension (1) and headache (2). One pt died from a fungal infection 3 mo.after R therapy. In this report, R ± other agents was effective and well-tolerated producing a 71% response rate with clinically meaningful response durations. LPDs were reported in 63% of pts. Studies of R to prospectively assess treatment and response variables, particularly among pts with with W-Ab AIHA, are warranted.

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Latina, Mark A., Shlomo Melamed, Wayne F. March, Michael A. Kass, and Allan E. Kolker. "Gonioscopic Ab Interno Laser Sclerostomy." Ophthalmology 99, no. 11 (November 1992): 1736–44. http://dx.doi.org/10.1016/s0161-6420(92)31738-5.

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5

Mack, Hans-Georg, and Heinz Oberhammer. "How reliable are ab initio calculations?" Journal of Molecular Structure: THEOCHEM 258, no. 1-2 (June 1992): 197–98. http://dx.doi.org/10.1016/0166-1280(92)85041-i.

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6

Szczȩśniak, M. M., and G. Chałasiński. "Ab initio calculations of nonadditive effects." Journal of Molecular Structure: THEOCHEM 261 (July 1992): 37–54. http://dx.doi.org/10.1016/0166-1280(92)87063-6.

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7

Dowd, MK, AD French, and PJ Reilly. "MM3(92) Analysis of Inositol Ring Puckering." Australian Journal of Chemistry 49, no. 3 (1996): 327. http://dx.doi.org/10.1071/ch9960327.

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The molecular mechanics method MM3(92) was used to study the puckering of the nine inositol isomers. Energy surfaces were generated based on the Cremer-Pople puckering definitions and the geometric plate carree representations of Pickett and Strauss. Chair forms are favoured for all the inositol isomers in agreement with experiment. The lowest energy non-chair form, more than 10 kJ/mol in free energy above the chair, is a skew of muco-inositol , in which all the hydroxyls are oriented either equatorially or pseudo-equatorially. Hydrogen-hydrogen coupling constants are in good agreement with experiment. The predicted order of stability for the isomers is scyllo - > myo - > chiro - > neo- > � epi -> muco - ≈ allo -> cis-inositol. This order generally agrees with Angyal's proposed stability order based on the number and type of gauche and 1,3-diaxial ring substituents. In contrast with recent ab initio calculations and values calculated with Angyal's method, the MM3 � gas-phase free energy of scyllo-inositol was lower than that of myo-inositol by 5.5 kJ/mol. The calculated transition energy for the chair-to-chair conversion of cis-inositol differs by 12.5-17.2 kJ/mol from the experimental value, depending on the strength of the electrostatic field.

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Schatz, Jürgen. "Recent Application of ab initio Calculations on Calixarenes and Calixarene Complexes. A Review." Collection of Czechoslovak Chemical Communications 69, no. 6 (2004): 1169–94. http://dx.doi.org/10.1135/cccc20041169.

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In this short review the application of ab initio quantum chemical calculations on calixarenes and calixarene complexes is highlighted. The main focus lies on results obtained mainly during the last 2-3 years. A review with 92 references.

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9

Zhou, Grace, Dongyao Ni, Runbin Yan, Xiaoqing Chen, Xianjie Liu, Yuxin Tang, and Jie Ma. "New generation of oncolytic herpesviruses embodying immunotherapeutic genes encoding IL-12 and anti-PD-1 antibody." Journal of Global Oncology 5, suppl (October 7, 2019): 92. http://dx.doi.org/10.1200/jgo.2019.5.suppl.92.

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92 Background: Systemic administration of checkpoint inhibitors alone and especially concurrent with intratumoral administration of oncolytic herpes simplex viruses (oHSV) have a major impact on cancer therapy marred by rare failures of healthy organs. Methods: We constructed 3 recombinant oHSVs expressing no immunomodulatory genes (T1 series), murine or human IL-12 (T2 series) and murine or human IL-12 and anti-PD-1 antibody (T3 series). We compared 1) the oncolytic effects of a single or multiple intratumoral injection(s) of T1, T2 and T3 series oHSVs, 2) the effectiveness of intratumoral injection of T3 oHSV with systemic administration of anti PD-1 ab and IL12 alone or in combinations with T1. Results: Insertion of gene encoding PD-1 Ab significantly augmented the oncolytic activity of oHSV bereft of immunostimulatory genes (T1 series) or expressing IL-12 alone (T2 series). In syngeneic mice the T3 series oHSV expressing murine IL-12 and PD-1 Ab was effective against a variety of murine tumors. Concurrent with enhanced cytolytic activity the T3 induced significant intratumoral accumulation of IL-12, PD-1 Ab and IFN-γ. Consistent with an earlier report of an inverse correlation between the volume of the tumor and the quantity of retained IFN-γ. The most effective oncolytic effect resulted from the administration of T3855 expressing both IL12 and anti PD-1 antibody or T2850 concurrently with intraperitoneal administration of anti PD-1 antibody alone. The least effective were single intraperitoneal administration of IL12 or PD-1 antibody. Intratumoral injection of T3 oHSV was most effective against murine tumors in comparison of either systemic administration of anti PD-1 ab and IL12 or intratumoral injection of T1 in combinations of systemic administration of anti PD-1 ab and IL12. Conclusions: We report the marriage in a single therapeutic agent of three distinct cancer therapies: the targeting of cancer cells by oncolytic viruses, the stimulation of immune system by IL12, and the production of immunotherapeutic antibodies against PD-1. The significant finding reported in this article is that the anti-tumor responses remain concentrated in the tumor environment.

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Bolin, N. J., and P. Norén. "Use of reagents in Boliden Mineral AB." Minerals Engineering 5, no. 3-5 (March 1992): 311–16. http://dx.doi.org/10.1016/0892-6875(92)90213-s.

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Chung-Phillips, Alice. "An ab initio study of internal rotation." Journal of Molecular Structure: THEOCHEM 257, no. 3-4 (May 1992): 417–35. http://dx.doi.org/10.1016/0166-1280(92)85053-n.

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Guo, Hong, and Martin Karplus. "Ab initio studies of methylated 1,3-butadienes." Journal of Molecular Structure: THEOCHEM 260 (July 1992): 347–93. http://dx.doi.org/10.1016/0166-1280(92)87055-5.

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Guo, Ting, and Gustavo E. Scuseria. "Ab initio calculations of tetrahedral hydrogenated buckminsterfullerene." Chemical Physics Letters 191, no. 6 (April 1992): 527–32. http://dx.doi.org/10.1016/0009-2614(92)85584-w.

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Yancey, W. Bruce, Franco Silvestris, Michael Conlon, Martin Rodriguez, Christine Malone, and Ralph C. Williams. "Human anti-F(ab′)2 antibodies show preferential reactivity for F(ab′)2 molecules bearing λ light chains." Clinical Immunology and Immunopathology 65, no. 2 (November 1992): 176–82. http://dx.doi.org/10.1016/0090-1229(92)90221-9.

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Ojeda-Aravena, Alex, Jairo Azócar-Gallardo, Tomás Herrera-Valenzuela, and José Manuel García-García. "Relación de la Asimetría Bilateral y el Déficit Bilateral con la Velocidad del Cambio de Dirección en Atletas Cadetes de Karate: Un estudio Piloto (Relationship of Bilateral Asymmetry and Bilateral Deficit with the Change of Direction Speed in Cadet Kara." Retos 42 (March 14, 2021): 100–108. http://dx.doi.org/10.47197/retos.v42i0.86397.

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Antecedentes: La Asimetría Bilateral (AB) y el Déficit Bilateral (DBL) y su potencial relación negativa con el rendimiento físico es actualmente estudiada, aunque la relación con la velocidad del cambio de dirección (CODS) y el sprint lineal (5-M) en atletas de karate se desconoce. Objetivo: Examinar las correlaciones entre la AB y el DBL con el CODS y 5-M, así como entre el salto horizontal con el CODS y 5-M. Métodos: Diez atletas hombres de categoría cadetes participaron voluntariamente de este estudio. Entre las habilidades físicas evaluadas se incluyeron: salto horizontal bilateral (SBJ), salto horizontal unilateral derecho (RSBJ), salto horizontal unilateral izquierdo (LSBJ), CODS y 5-M. Posteriormente, la AB y el DBL fueron calculados. Resultados: Se reportó una baja AB (5.17 ± 3.61%) y presencia de DBL (-36.9 ± 6.2 %). Correlaciones moderadas entre la AB con CODS (r = -.38; R2 = .15%; p = .30) y 5-M (r = -.47; R2 = .22%; p = .19) y entre DBL con 5-M (r = .51; R2 = .26%; p = .16) y bajas con CODS (r = .20; R2 = .04%; p = .60). Correlaciones significativas (p < .05) entre CODS con RSBJ (r = -.92; R2 = .85%; p = .00), SBJ (r = -.87; R2 = .75%; p = .00) y LSBJ (r = -.82; R2 = .67%; p = .00). Conclusiones: La AB y el DBL se relacionarían negativamente con el CODS y 5-M. Aunque, el CODS se relaciona con la fuerza explosiva horizontal bilateral y unilateral. Abstract. Background: Bilateral asymmetry (AB) and Bilateral Deficit (DBL) and their potential negative relationship with physical performance is currently studied, although the relationship with change of direction speed (CODS) and linear sprint (5-M) in karate athletes is unknown. Aim: To examine correlations between AB and DBL with CODS and 5-M, as well as between horizontal jump with CODS and 5-M. Methods: Ten male cadet athletes voluntarily participated in this study. The physical abilities assessed included: bilateral horizontal jump (SBJ), right unilateral horizontal jump (RSBJ), left unilateral horizontal jump (LSBJ), CODS and 5-M. Subsequently, AB and DBL were calculated. Results: Low AB (5.17 ± 3.61%) and presence of DBL (-36.9 ± 6.2 %) were reported. Moderate correlations between AB with CODS (r = -.38; R2 = .15%; p = .30) and 5-M (r = -.47; R2 = .22%; p = .19) and between DBL with 5-M (r = .51; R2 = .26%; p = .16) and low with CODS (r = .20; R2 = .04%; p = .60). Significant correlations (p < .05) between CODS with RSBJ (r = -.92; R2 = .85%; p = .00), SBJ (r = -.87; R2 = .75%; p = .00) and LSBJ (r = -.82; R2 = .67%; p = .00). Conclusions: AB and DBL would be negatively related to CODS and 5-M. However, CODS is related to bilateral and unilateral horizontal explosive strength.

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Kilic, Bilal. "Self-Medication Among Ab Initio Pilots." Aerospace Medicine and Human Performance 92, no. 3 (March 1, 2021): 167–71. http://dx.doi.org/10.3357/amhp.5718.2021.

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INTRODUCTION: Pilots are more aware of drugs and self-medication in the internet age. However, they are unaware of the effects of self-medication, which may impede their cognitive and decision-making performance. The aim of this study was to determine the awareness levels of ab initio (student) pilots on self-medication and factors contributing to the prevalence of self-medication among them. To the best of the authors knowledge, this is the first study examining ab initio pilots knowledge on medication use and the causality of self-medication among them.METHODS: A 17-item questionnaire was developed and administered online to 500 students across 5 flight training organizations (FTO) in Turkey. The response rate was 97/500. For the descriptive analysis of the data, SPSS (the Statistical Package for the Social Sciences) was used.RESULTS: Based on the results, fear of medical disqualification and job loss is the most significant factor resulting in the prevalence of self-medication among ab initio pilots. Most of the ab initio pilots (88.7%, N 86) were aware of self-medication and its threat to flight safety. Furthermore, three factors influencing the level of awareness and knowledge of ab initio pilots on this subject were evaluated.DISCUSSION: All flight training organizations should educate ab initio pilots on the consequences of self-medication. Furthermore, ab initio pilots should be encouraged to consult an aeromedical examiner with any ailment before a flight.Kilic B. Self-medication among ab initio pilots. Aerosp Med Hum Perform. 2021; 92(3):167171.

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Ferreira, Márcia M. C. "Ab-initio atomic charges from atomic polar tensors." Journal of Molecular Structure 266 (March 1992): 223–28. http://dx.doi.org/10.1016/0022-2860(92)80070-x.

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Seel, Max, and Ravindra Pandey. "Ab initio electronic structure of superionic conductor Li3P." Solid State Ionics 53-56 (July 1992): 924–27. http://dx.doi.org/10.1016/0167-2738(92)90272-q.

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Dolg, Michael, Hermann Stoll, and Heinzwerner Preuss. "Ab initio pseudopotential study of YbH and YbF." Chemical Physics 165, no. 1 (September 1992): 21–30. http://dx.doi.org/10.1016/0301-0104(92)80039-x.

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Giménez, Xavier, Miquel Moreno, and José M. Lluch. "Ab initio study of the NH3 + OH reaction." Chemical Physics 165, no. 1 (September 1992): 41–46. http://dx.doi.org/10.1016/0301-0104(92)80041-s.

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Ewig, Carl S., Joel Tellinghuisen, and Marcus H. Mendenhall. "Ab initio F-center electron topology in LiF." Chemical Physics Letters 188, no. 5-6 (January 1992): 501–9. http://dx.doi.org/10.1016/0009-2614(92)80856-7.

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Velino, Biagio, Elisabetta Cané, Agostino Trombetti, Giorgio Corbelli, Francesco Zerbetto, and Walther Caminati. "Microwave spectrum and ab initio calculations of indazole." Journal of Molecular Spectroscopy 155, no. 1 (September 1992): 1–10. http://dx.doi.org/10.1016/0022-2852(92)90543-w.

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23

Fiorentini, Vincenzo. "A note on AB INITIO semiconductor band structures." Solid State Communications 83, no. 11 (September 1992): 871–75. http://dx.doi.org/10.1016/0038-1098(92)90903-m.

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Jing, Ze, and Jerry L. Whitten. "Ab initio studies of Si(100) surface reconstruction." Surface Science 274, no. 1 (July 1992): 106–12. http://dx.doi.org/10.1016/0039-6028(92)90104-e.

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Trygg, Joakim, Börje Johansson, and M. S. S. Brooks. "Ab initio calculation of the magnetism in GdFe12." Journal of Magnetism and Magnetic Materials 104-107 (February 1992): 1447–48. http://dx.doi.org/10.1016/0304-8853(92)90657-a.

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Cvetkovic, Z., and B. Novakovic. "Orbits for sixteen binaries." Serbian Astronomical Journal, no. 173 (2006): 73–82. http://dx.doi.org/10.2298/saj0673073c.

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In this paper orbits for 13 binaries are recalculated and presented. The reason is that recent observations show higher residuals than the corresponding ephemerides calculated by using the orbital elements given in the Sixth Catalog of Orbits of Visual Binary Stars. The binaries studied were: WDS 00182+7257 = A 803, WDS 00335+4006 = HO 3, WDS 00583+2124 = BU 302, WDS 01011+6022 = A 926, WDS 01014+1155 = BU 867, WDS 01112+4113 = A 655, WDS 01361?2954 + HJ 3447, WDS 02333+5219 = STT 42 AB,WDS 04362+0814 = A 1840 AB,WDS 08017?0836 = A 1580, WDS 08277?0425 = A 550, WDS 17471+1742 = STF 2215 and WDS 18025+4414 = BU 1127 Aa-B. In addition, for three binaries - WDS 01532+1526 = BU 260, WDS 02563+7253 = STF 312 AB and WDS 05003+3924 = STT 92 AB - the orbital elements are calculated for the first time. In this paper the authors present not only the orbital elements, but the masses dynamical parallaxes, absolute magnitudes and ephemerides for the next five years, as well.

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Kilic, Bilal. "Fatigue Among Student Pilots." Aerospace Medicine and Human Performance 92, no. 1 (January 1, 2021): 20–24. http://dx.doi.org/10.3357/amhp.5631.2021.

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INTRODUCTION: Fatigue is an important phenomenon in modern aviation. Despite the progress in research concerning fatigue among civil aviation and military pilots, fatigue in student pilots has remained unexamined. The aim of this study was to examine fatigue among ab-initio pilots. In this study, the fatigue model previously proposed and used in the literature is redesigned for ab-initio pilots.METHOD: A 48-item questionnaire was applied. Factor analysis was performed using SPSS. The data were collected from 114 ab-initio pilots.RESULTS: It was determined that 23% (N 26) of the participants included in the study were women and 77% (N 88) were men. When the license types of the participants were analyzed, it was seen that 11% (N 13) had commercial pilot licenses (CPL; N 80), 70% had private pilot licenses (PPL), and 18% (N 21) had student pilot licenses (SPL). Results showed that seven performance factors (types of flight, training scheduling, crew composition, environment of the aircraft, types of accommodation, flight training-related issues, and biological issues) affect ab-initio pilots fatigue on various levels.DISCUSSION: The findings may help flight training organizations and ab-initio pilots take assertive preventive measures against fatigue.Kilic B. Fatigue among student pilots. Aerosp Med Hum Perform. 2021; 92(1):2024.

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Durig, J. R., Min Joo Lee, H. M. Badawi, J. F. Sullivan, and D. T. Durig. "Some applications of ab initio calculations in molecular spectroscopy." Journal of Molecular Structure 266 (March 1992): 59–64. http://dx.doi.org/10.1016/0022-2860(92)80050-r.

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Spoliti, M., N. Sanna, and V. Di Martino. "Ab initio study on the MBF4 and MAlF4 molecules." Journal of Molecular Structure: THEOCHEM 258, no. 1-2 (June 1992): 83–107. http://dx.doi.org/10.1016/0166-1280(92)85034-i.

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Schulman, Jerome M., and Raymond L. Disch. "Ab initio heats of formation of medium-sized hydrocarbons." Journal of Molecular Structure: THEOCHEM 259 (July 1992): 173–79. http://dx.doi.org/10.1016/0166-1280(92)87012-o.

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Colt, John R., and Gustavo E. Scuseria. "An ab initio study of the C78 fullerene isomers." Chemical Physics Letters 199, no. 6 (November 1992): 505–12. http://dx.doi.org/10.1016/0009-2614(92)85001-q.

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Tao, Fu-Ming, and Yuh-Kang Pan. "An accurate ab initio calculation of the Ne2 potential." Chemical Physics Letters 194, no. 3 (June 1992): 162–66. http://dx.doi.org/10.1016/0009-2614(92)85527-h.

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Cheam, T. C. "Ab initio vibrational spectra of hydrogen-bonded N-methylacetamide." Journal of Molecular Structure: THEOCHEM 257, no. 1-2 (May 1992): 57–73. http://dx.doi.org/10.1016/0166-1280(92)87180-8.

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Goto, Kenichi, Yasuo Kansui, Kunihiko Ichishima, Toshio Ohtsubo, Kiyoshi Matsumura, and Takanari Kitazono. "92 REDUCED ACTIVITY OF SKCA CHANNELS ACCOUNTS FOR THE IMPAIRED EDHF-MEDIATED RELAXATION IN MESENTERIC ARTERIES OF STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RATS." Journal of Hypertension 30 (September 2012): e29. http://dx.doi.org/10.1097/01.hjh.0000419917.31549.ab.

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Кручинин, В. Н., Т. В. Перевалов, Г. Н. Камаев, С. В. Рыхлицкий, and В. А. Гриценко. "Оптические свойства нестехиометрического оксида кремния SiO-=SUB=-x-=/SUB=- (x<2)." Журнал технической физики 127, no. 11 (2019): 769. http://dx.doi.org/10.21883/os.2019.11.48513.136-19.

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Abstract The optical properties of amorphous nonstoichiometric silicon oxide (SiO_ x ) films of variable composition ( x = 0 . 62–1 . 92) formed by plasma-enhanced chemical vapor deposition are studied in the spectral range of 1 . 12–4 . 96 eV. Spectral ellipsometry showed that the refractive index dispersion character allows one to assign the formed SiO_ x films to silicon-like films, dielectrics, or intermediate-conductivity-type films depending on the content of oxygen in the gas phase during synthesis. A model of the SiO_ x structure for ab initio calculations is proposed and describes well the experimental optical spectra. Ab initio calculations of the dependences of the SiO_ x refractive index and band gap on stoichiometry parameter x are performed.

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Chatterjee, K. K., J. R. Durig, and Stephen Bell. "Microwave spectrum, r0 structure, and ab initio calculations for trimethylphosphine." Journal of Molecular Structure 265, no. 1-2 (January 1992): 25–45. http://dx.doi.org/10.1016/0022-2860(92)80236-b.

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Hiraoka, Yoshiko Someya, Masao Mashita, Tsukasa Tada, and Reiko Yoshimura. "Ab initio molecular orbital study on thermal decomposition of tertiarybutylphosphine." Applied Surface Science 60-61 (January 1992): 246–50. http://dx.doi.org/10.1016/0169-4332(92)90424-v.

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Clarke, L. J., I. Štich, and M. C. Payne. "Large-scale ab initio total energy calculations on parallel computers." Computer Physics Communications 72, no. 1 (October 1992): 14–28. http://dx.doi.org/10.1016/0010-4655(92)90003-h.

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Kelterer, Anne-Marie, Michaela Flock, and Michael Ramek. "Ab initio SCF investigation of 3-aminopropanol and 3-aminopropanal." Journal of Molecular Structure: THEOCHEM 276 (December 1992): 35–59. http://dx.doi.org/10.1016/0166-1280(92)80022-e.

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Ramusino, M. Cotta, G. La Manna, and O. Tomagnini. "Ab initio calculation of protonation and lithiation energy of acetamidoxime." Journal of Molecular Structure: THEOCHEM 254 (February 1992): 473–80. http://dx.doi.org/10.1016/0166-1280(92)80090-9.

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De Maré, George R., and Earl M. Evleth. "Ab initio study of C-H bond breaking in olefins." Journal of Molecular Structure: THEOCHEM 259 (July 1992): 273–88. http://dx.doi.org/10.1016/0166-1280(92)87019-v.

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McKean, D. C., I. Torto, James E. Boggs, and Kangnian Fan. "Infrared and ab initio studies of molecules containing SiH bonds." Journal of Molecular Structure: THEOCHEM 260 (July 1992): 27–46. http://dx.doi.org/10.1016/0166-1280(92)87033-v.

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Bouteiller, Y., S. Sadi, Z. Latajka, and H. Ratajczak. "Ab initio study of proton transfer between methylnitroamine and trimethylamine." Chemical Physics Letters 199, no. 1-2 (October 1992): 55–61. http://dx.doi.org/10.1016/0009-2614(92)80048-g.

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Martin, J. M. L., and Timothy J. Lee. "Accurate ab initio quartic force fields for borane and BeH2." Chemical Physics Letters 200, no. 5 (December 1992): 502–10. http://dx.doi.org/10.1016/0009-2614(92)80082-m.

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Pasinszki, Tibor, Tamás Veszprémi, and Miklós Fehér. "The equilibrium structure of methyl pseudohalides: an ab initio study." Chemical Physics Letters 189, no. 3 (February 1992): 245–51. http://dx.doi.org/10.1016/0009-2614(92)85133-u.

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Kato, Hiroshi, Koichi Yamashita, and Keiji Morokuma. "Ab initio MO study of neutral and cationic boron clusters." Chemical Physics Letters 190, no. 3-4 (March 1992): 361–66. http://dx.doi.org/10.1016/0009-2614(92)85352-b.

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Seijo, Luis, Zoila Barandiarán, and Sigeru Huzinaga. "Atomic valence correlation energies from ab initio model potential calculations." Chemical Physics Letters 192, no. 2-3 (May 1992): 217–20. http://dx.doi.org/10.1016/0009-2614(92)85455-j.

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Aleman, Carlos, Juan J. Perez, and Alan Hinchliffe. "Ab initio SCF-MO incremental triplet polarizabilities of neon clusters." International Journal of Mass Spectrometry and Ion Processes 122 (December 1992): 331–36. http://dx.doi.org/10.1016/0168-1176(92)87023-8.

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Lievin, Jacques. "Ab initio characterization of the state of the acetylene molecule." Journal of Molecular Spectroscopy 156, no. 1 (November 1992): 123–46. http://dx.doi.org/10.1016/0022-2852(92)90098-9.

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Gammal, Ayman. "1266. Multifaceted Infection Control Strategies to Control Multidrug-Resistant Acinetobacter baumanii in Adult Intensive Care Unit in a Tertiary Hospital in Eastern Region, Saudi Arabia." Open Forum Infectious Diseases 5, suppl_1 (November 2018): S386. http://dx.doi.org/10.1093/ofid/ofy210.1099.

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Abstract Background Multidrug-resistant Acinetobacter baumanii (MDR-AB) has emerged globally as a significant pathogen in hospitals. During 2010, our hospital experienced an increase of MDR-AB in Adult intensive care unit (ICU). Our adult ICU is consists of 10 acute care beds. The hospital is a tertiary institution located in Eastern region of Saudi Arabia. Multidisciplinary team was formed to implement and determine the effect of multifaceted strategies in controlling MDR-AB. Methods Active surveillance culture (ASC) was initiated to determine the prevalence rate of MDR-AB per 1,000 patient-days (PD). Using ASC, which was done during admission in ICU, after 48 hours of admission and every week for all patients if there is a positive MDR-AB case, acquisition rate of MDR-AB was calculated per 1,000 PD. Average daily colonization pressure was also monitored. In addition, a multifaceted infection control strategies were carried out. These include hand hygiene, contact isolation, cohorting of patients, Chlorhexidine bath, and environmental cleaning and disinfection. Compliance with hand hygiene was observed using direct observation method. We use the Fluorescent Gel Method for evaluating the thoroughness of disinfection and cleaning for environmental surfaces. Results Hand hygiene compliance of HCWs initially was 89%, in 2017 was increased to 98%. Daily Chlorhexidine bath was adopted for all patients in ICU. Initially, the compliance for thoroughness of disinfection and cleaning is 84.6% it was increased to 92% in 2013–2017. Prevalence rate of MDR-AB was 20.7/1,000 PD in 2010, it was decreased by 50% in 2011–2012. In 2017, declined to 0.9/1,000 PD. MDR-AB acquisition rate was 11.8/1,000 PD in 2010, it was decreased by 57% in 2011–2012. In 2017, dropped to 0.6/1,000 PD. Average daily colonization pressure was 0.21 in 2010. In 2011–2012, it was decreased by 31%. In 2017, it was reduced to 0.02. Death rate among MDR-AB patient in 2010 was 25.7%. It was decreased to 14% in 2011–2012. In 2017, an enormous drop to 0% was achieved. Conclusion Implementing these multifaceted strategies help in controlling MDR-AB in our hospital. The commitment and adherence of the HCW to all infection control strategies are essential in sustaining low prevalence rate and acquisition rate of MDR-AB. Disclosures All authors: No reported disclosures.

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