Relevant bibliographies by topics / ABO and Rhesus factor

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Academic literature on the topic 'ABO and Rhesus factor'

Author: Grafiati
Published: 5 June 2025
Last updated: 25 June 2025

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Journal articles on the topic "ABO and Rhesus factor"

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Boycheva, Maria. "BLOOD-GROUP ABO AND RHESUS FACTOR SYSTEMS DISTRIBUTION IN INDIVIDUALS OF VIETNAMESE NATIONALITY." Journal Scientific and Applied Research 12, no. 1 (2017): 74–78. http://dx.doi.org/10.46687/jsar.v12i1.229.

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The article reports the results of a study of blood group ABO and Rhesus factor systems conducted on 423 Vietnamese citizens (104 men and 319 women) aged 19 to 77 who lived or are currently living in Bulgaria. The frequency of the individual groups of the AB0 system is: 0 - 49,88%, B - 25,06%, A - 21,75%, AB - 3,31%, and the gene frequency - r = 0,711, q = 0,155, p = 0.134. Only subsets A1 and A1B were detected in the ABO system. There was only Rh in the studied population.
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Onah, Ikechukwu Eugene, Ezinne Veronica Moses, Ifeyinwa Esther Ugwuoke, Sabina Chioma Eze, Jude Ifeanyichukwu Okwor, and Patience Obiageli Ubachukwu. "Comparative ABO blood group and rhesus factor distribution between homogenous and heterogenous populations in South Eastern Nigeria." Asian Journal of Medical Sciences 10, no. 5 (2019): 37–42. http://dx.doi.org/10.3126/ajms.v10i5.25013.

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Background: The ABO blood group and Rhesus (Rh) factor remain the most important blood group in transfusion medicine. Knowledge of ABO and rhesus blood group distribution within a population is indispensable for transfusion medicine, clinical and marriage counselling.
 Aims and Objectives: The objectives of this study were to provide data and compare the pattern of ABO and rhesus blood group distribution between a homogenous and a heterogenous population.
 Material and Methods: Blood was collected from 352 University students representing a heterogenous population and 235 primary school pupils in a local community representing homogenous population. The ABO and rhesus blood groups were determined using white tile and agglutination methods.
 Results: Among the 352 and 235 individuals studied in UNN and HFNP, blood groups O had the highest frequency with 54.80% and 51.06% respectively while blood group AB had the least frequency of 4.50% and 3.40% in UNN and HFNP respectively. Rhesus positive had the highest frequency of 88.63% and 95.33% while rhesus negative had the frequencies of 11.35% and 4.68% in UNN and HFNP respectively. Rhesus negative was highest among females in UNN 26 (7.37%) while males had the highest rhesus negative 7 (2.98%) in HFNP. In both study populations, there was no significant difference in ABO and rhesus blood group distribution between the males and females (P > 0.05).
 Conclusions: A homogenous population is associated with low prevalence of rhesus negative compared to a heterogenous population.
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Bamou, Roland, and Silas L. Sevidzem. "ABO/Rhesus blood group systems and malaria prevalence among students of the University of Dschang, Cameroon." MalariaWorld Journal 7, no. 4 (2024): 1–4. https://doi.org/10.5281/zenodo.10797079.

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<strong>Background.</strong> A study was carried out on students of the University of Dschang, Cameroon, to examine the relationship between ABO blood group, rhesus factor and prevalence of <em>Plasmodium falciparum</em> infection. <strong>Materials and methods.</strong> Blood group and rhesus factor were typed by agglutination using antisera while malaria infection was determined using Rapid Diagnostic Test CareStart malaria HRP2 pf. Out of 620 students 582 were screened for ABO blood group and Rhesus factor, and 276 were tested for <em>P. falciparum</em> infection. <strong>Results.</strong> Faculty of Science (FS) members and male students were highly represented, with 356 (61.2% ) and 303 (52.1%) participants, respectively. Blood group O was most common (48.8%), followed by blood group A (25.8%), B (23.0%) and AB (2.4%). Total percentage of rhesus positive was 92.4%, and its distribution varied across ABO blood groups. Of the 276 students examined for malaria infection, 27 were found positive (9.8%). Except for blood group AB individuals, of which none were infected, malaria infection did not vary among blood groups. <strong>Conclusion.</strong> Rhesus factor and blood group did not impact on malaria infection in the hypo-endemic highland area of Dschang, Cameroon.
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Akogu, Simon P. O., Owemidu Idowu Olumorin, and Shedrack Egbunu Akor. "Distribution of ABO, Rhesus Factor Blood Phenotype and Haemoglobin Genotype among Antenatal Clinic Attendees in Anyigba, North Central Nigeria." European Journal of Medical and Health Sciences 3, no. 6 (2021): 11–13. http://dx.doi.org/10.24018/ejmed.2021.3.6.954.

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Background: In the practice of obstetrics and gynecology, the ABO and Rhesus factor (Rh) blood type are important. Blood typing for blood transfusion of compatible blood is very common in emergency and routine care. There is a scanty literature on the distribution of ABO and Rhesus blood types in Anyigba, (North central) Nigeria. Objective: This study aims to determine the distribution of ABO blood and Rhesus blood group phenotypes and Hemoglobin genotypes among antenatal clinic attendees in a teaching hospital. Methods: Antenatal records of attendees (October 2017 to September 2020) at the Kogi State University Teaching Hospital were retrieved and results of antenatal hematological investigations were collected using a structured tool.Bio data, ABO blood group, Rhesus group phenotype and Hemoglobin genotype were collected, inputted and analyzed using SPSS version 20. Results: The mean age was 26 +/- 7years, blood group O is most prevalent,561 (53.6%) then A 276 (26.4%), B 189 (18.1%) and AB,21 (2%).1014 (96.4%) were Rhesus D positive, 33 (3.1%) were Rhesus D negative. For hemoglobin genotype, 786 (75.1%) were AA, 258 (24.6%) were AS, AC were 3 (0.3%). Conclusion: The distribution of the ABO, the Rhesus (D) blood groups and hemoglobin genotypes are in concurrence with the findings of previous studies; Blood group O is the most prevalent and AB the least prevalent, Rhesus (D) positive in the population is high and the hemoglobin genotype AA is the most prevalent. There is no association between blood group phenotypes studied and the hemoglobin genotypes.
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Dhana Reswari, Putu Ayu, Yustisia Amalia, and Renata Primasari. "Sosialisasi Sosialisasi Dan Edukasi Tentang Donor Rhesus Negatif Di Unit Tranfusi Darah PMI Kota Surabaya Tahun 2020." Jurnal of Community Health Development 3, no. 2 (2022): 16. http://dx.doi.org/10.20884/1.jchd.2022.3.2.4806.

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Abstrak Golongan darah tidak hanya dapat dibedakan menjadi A, B, AB, atau O menurut sistem ABO, tetapi juga melalui sistem faktor Rhesus (Rh). Komponen ini diperiksa dalam pemeriksaan golongan darah. Faktor rhesus dilihat dari keberadaan protein bawaan pada sel darah merah. Meskipun populasi rhesus negatif secara keseluruhan didominasi oleh orang-orang Kaukasia, rhesus negatif juga ditemukan di orang-orang Asia, tak terkecuali Indonesia. Menurut Badan Pusat Statistik (BPS), pada tahun 2010 populasi rhesus negatif di Indonesia tidak mencapai angka 1 % (sekitar 1,2 juta orang). Secara alami, gen pembawa rhesus negatif bersifat resesif, sedangkan rhesus positif bersifat dominan maka jumlah orang dengan rhesus negatif menjadi lebih sedikit. Pengabdian Masyarakat ini bekerja sama dengan Unit Tranfusi Darah (UTD) PMI Kota Surabaya dalam bentuk Sosialisasi dan Edukasi Tentang Donor Rhesus Negatif Di PMI Kota Surabaya agar warga masyarakat awam pun mengerti bahwa golongan darah tidak hanya A,B,AB dan O tetapi juga ada rhesus terutama tentang rhesus negatif. Kata Kunci : Rhesus Negatif, Golongan darah, ABO Abstract Blood types can not only be distinguished into A, B, AB, or O according to the ABO system, but also through the Rhesus (Rh) factor system. This component is examined in the blood group examination. The rhesus factor is seen from the presence of an innate protein in red blood cells. Although the overall rhesus negative population is dominated by Caucasians, rhesus negative people are also found in Asian people, including Indonesia. According to the Central Statistics Agency (BPS), in 2010 the rhesus negative population in Indonesia did not reach 1% (about 1.2 million people). Naturally, the gene carrying rhesus negative is recessive, while rhesus positive is dominant, so the number of people with rhesus negative becomes less. This Community Service collaborates with the Blood Transfusion Unit (UTD) of PMI Surabaya City in the form of Socialization and Education About Rhesus Negative Donors at PMI Surabaya City so that ordinary people understand that blood types are not only A, B, AB and O but there is also Rhesus especially about rhesus negative. Keywords: Rhesus Negative, Blood type, ABO
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Abuladze, Salome, Leila Akhvlediani, Marina Nagervadze, et al. "ABO Blood Groups, Rhesus Factor, and Rheumatoid Arthritis." Theoretical and Natural Science 67, no. 1 (2024): 30–36. https://doi.org/10.54254/2753-8818/2024.18063.

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The ABO and Rhesus blood group systems play critical roles in clinical practice, particularly concerning their associations with autoimmune diseases, including rheumatoid arthritis (RA). This study aimed to investigate the relationship between ABO blood types, Rh factors, and RA in a Georgian population. A total of 157 participants were included, comprising 93 RA patients and 64 healthy controls. Blood samples were analyzed for ABO and Rh D blood group determination, revealing that blood type O was the most prevalent among RA patients (50.5%), followed by type A (35.5%), while the control group exhibited similar distributions (O: 54.7%, A: 34.4%). The Rh factor analysis indicated a slightly higher prevalence of Rh-positive individuals in the RA group (84 patients) compared to Rh-negative individuals (9 patients). The overall distribution of blood types in RA patients closely mirrored that of the general population, indicating no significant link between ABO blood types and RA. Further research is warranted to explore these associations and their implications for RA pathogenesis and potential therapeutic targets.
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Valikhani, Mahin, Sima Kavand, Siavash Toosi, Golnaz Kavand, and Maryam Ghiasi. "ABO blood groups, rhesus factor and pemphigus." Indian Journal of Dermatology 52, no. 4 (2007): 176. http://dx.doi.org/10.4103/0019-5154.37720.

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Maha, Tareq Hussein. "Study of blood groups and Rhesus factor in beta thalassemia patients undergoing blood transfusions." International Journal of Biomolecules and Biomedicine (IJBB) 13, no. 6 (2021): 1–6. https://doi.org/10.5281/zenodo.8332093.

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Beta thalassemia is the most common genetic blood disease, affecting millions of people in both developing and developed countries including Iraq. Patients with thalassemia require frequent blood transfusions, which can cause a variety of complications. Several researches have looked into the link between ABO blood groups and diseases. The associations of ABO blood group with thalassemia have not been extensively studied. In order to know the prevalence of thalassemia according to age, gender and blood group frequency, a study was conducted on 200 individuals, 100 of them were a control sample, which was considered a standard sample, while the rest 100 individuals were infected with beta thalassemia. The study aims to find out any relationship between the frequency of blood group phenotypes and susceptibility to thalassemia compared to the control sample. Our findings indicate that the prevalence of thalassemia was higher in female patients than in male patients. Found in the lowest age group 15-19 years. There was a significant difference (P 0.05) in the frequency of ABO blood groups that was O &gt; B &gt; A &gt; AB. A significant difference of Rh factor (P&lt;0.01) was found in the patients compared with the control group. The current study indicated the importance of the studied blood groups, as they are sources for detecting the risks of inheriting beta thalassemia or the variability in the likelihood of its appearance, and they can be used with other laboratory tests in genetic counseling. Published by the&nbsp;<strong>International Journal of Biomolecules and Biomedicine (IJBB)</strong>
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Perepelitsa, S. A., V. A. Sergunova, S. V. Alekseeva, and O. E. Gudkova. "ERYTHROCYTE MORPHOLOGY IN NEONATAL RHESUS FACTOR AND ABO ISOIMMUNIZATION." General Reanimatology 11, no. 2 (2015): 25. http://dx.doi.org/10.15360/1813-9779-2015-2-25-34.

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Edibamode, Ezon-Ebidor Innocent, Edet Iboro Efiong, Nicholas Asiwe, and Cynthia Eben Gobour. "Factors Related to Premature Canities; A Cross-sectional Study in Lagos State, Nigeria." Asian Journal of Advanced Research and Reports 18, no. 5 (2024): 144–55. http://dx.doi.org/10.9734/ajarr/2024/v18i5642.

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Background: Canities, or graying or whitening hair, is a natural part of aging caused by reduced melanin production. Premature canities occur in humans or animals at a young age, with factors such as genetics, lifestyle, and environmental influences contributing. The study aims to evaluate the relationship between ABO Blood type, rhesus Factor, Genotype, Lifestyle, and Premature canities.&#x0D; Methods: 259 respondents were involved and a cross-sectional descriptive study design was used to generate data. The respondents were selected using a multi-stage random sampling techniques and data collection was via descriptive questionnaire. Data obtained were analyzed using IBM SPSS version 25.&#x0D; Results: A study of 259 participants found no significant association between premature canities and ABO blood type, rhesus, and genotype while lifestyle factors like smoking, and alcohol intake showed an association. Canities were found in various head regions, with no differences between sexes. Smoking and alcohol intake were more common in males. Depression was negatively associated with non-premature and premature canities. Nutrition intake was similar, but high carbohydrate and vegetable consumption was found to be statistically different.&#x0D; Conclusion: No association between ABO blood type, rhesus factor, genotype with premature canities, and lifestyle (alcohol intake and smoking) showed possible association with premature canities.
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Dissertations / Theses on the topic "ABO and Rhesus factor"

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Chornogorets, Valeriya, and Валерія Чорногорець. "Study of genetic features of blood groups heredity according to the AB0 system and rhesus factor." Thesis, National Aviation University, 2021. https://er.nau.edu.ua/handle/NAU/50772.

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1. Рагимов А.А., Дашкова Н.Г. Основы трансфузионной иммунологии. М., 2004. С. 68. 2. Blood group terminology 2004: from the International Society of Blood Transfusion committee on terminology for red cell surface antigens / G. Daniels et al. Vox Sang. 2004. № 87. Р. 304-316. 3. Yamamoto F., Yamamoto M. Molecular genetic basis of porcine histo-blood group ABO system. Blood. 2001. Vol. 97, № 10. P. 3308–3310. 4. Лавряшина М.Б., Толочко Т.А., Волков А.Н. Аллоантигены крови человека: учеб. пособ. Кемерово: Кузбассвузиздат, 2006. 100 с. 5. Практическая трансфузиология / под ред. Г.И. Козинца. М.: Практическая медицина, 2005. 544 с.<br>The work is devoted to the problem of blood transfusion (namely, the study of the most common blood group and rhesus factor in countries), because this issue has become acute around the world. Today, blood transfusions are an acute social problem. Two classifications of human blood groups are of the greatest importance for clinical practice: the AB0 system and the rhesus system, due to the fact that these systems have the greatest antigenic power. Each human-to-human blood transfusion must take into account the compatibility of these two systems, because in the case of a human transfusion of another (incompatible) blood group, agglutination (gluing) and hemolysis (destruction) of erythrocytes occur, which can lead to death. It is also desirable to separate plasma and blood cells.<br>Робота присвячена проблемі переливання крові (а саме вивченню найпоширенішої групи крові та резус-фактора в країнах), оскільки ця проблема загострилася у всьому світі. Сьогодні переливання крові є гострою соціальною проблемою. Дві класифікації груп крові людини мають найбільше значення для клінічної практики: система AB0 та резус-система через те, що ці системи мають найбільшу антигенну силу. При кожному переливанні крові людині необхідно враховувати сумісність цих двох систем, оскільки у випадку переливання людиною іншої (несумісної) групи крові відбувається аглютинація (склеювання) та гемоліз (руйнування) еритроцитів, що може привести до смерті. Також бажано відокремити плазму та клітини крові.
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Adam, Maryse, and MARIE-ODILE PETILLON. "Allogreffes de moelle osseuse en situation d'incompatibilite abo-rhesus : a propos de 27 observations." Lille 2, 1989. http://www.theses.fr/1989LIL2M121.

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BARTHELEMY, ASTIC PASCALE. "Les allo-immunisations foeto-maternelles par antigenes erythrocytaires autres que abo et rhesus d : a propos de 114 cas." Lyon 1, 1993. http://www.theses.fr/1993LYO1M251.

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Setlai, Mojalefa Brian. "The correlation between the ABO blood group, plasma von Willebrand factor and the ristocetin cofactor activity." Thesis, Bloemfontein : Central University of Technology, Free State, 2006. http://hdl.handle.net/11462/78.

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Deschuyteneer, Aude. "Rhesus factors: structure-function analysis and physiological role in mouse." Doctoral thesis, Universite Libre de Bruxelles, 2014. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209354.

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Proteins of the conserved Mep-Amt-Rh superfamily, including mammalian Rhesus factors,<p>mediate ammonium transport. Ammonium is an important nitrogen source for the<p>biosynthesis of amino acids for instance but its accumulation is also known as cytotoxic in<p>animals. Nevertheless, the controlled disposal of ammonium in urine plays a critical role in<p>the regulation of the acid-base homeostasis. Alteration in ammonium transport via human Rh<p>proteins could have clinical outcomes. In this work, we addressed aspects of structurefunction<p>analysis of altered human Rhesus proteins using a heterologous expression system<p>and further characterized aspects of the patho-physiological roles of Rh proteins using<p>knockout mice models available in the laboratory.<p>Using a yeast-based expression assay, we characterized human Rh variants resulting from non<p>synonymous single nucleotide polymorphisms (nsSNPs) with known or unknown clinical<p>phenotypes. The HsRhAG variants (I61R, F65S) associated to overhydrated hereditary<p>stomatocytosis (OHSt), a disease affecting erythrocytes, proved affected in intrinsic<p>bidirectional ammonium transport, suggesting altered ammonium transport as a potential<p>hallmark of the disease. Moreover, these variants showed trans-dominant negative effects on<p>the activity of their native HsRhAG counterpart, suggesting altered cooperation of the<p>subunits in “heteromeric” transport complexes. On the other hand, we revealed that the<p>R202C variant of HsRhCG, the orthologue of mouse Rhcg required for optimal urinary<p>ammonium excretion and blood pH control, shows an impaired inherent ammonium transport<p>activity. HsRhCGR202C may potentially confer susceptibility to disorders leading to metabolic<p>acidosis for instance. <p>MmRhcg has been shown to be expressed in the male mice epididymal tract, its absence<p>leading to a more acidic luminal fluid and to a reduced male fertility. Using mice<p>models, we further investigated the role of Rhcg and Rhbg proteins in the male<p>reproductive function. <p><br>Doctorat en Sciences<br>info:eu-repo/semantics/nonPublished
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Parnell, Lisa Lynn. "Examination of Possible Protective Effect of Rhesus D Positive Blood Factor on Toxoplasma-related Depressive Symptoms in Pregnancy." Scholar Commons, 2014. https://scholarcommons.usf.edu/etd/5387.

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Toxoplasma gondii infects approximately one third of the population worldwide. There is strong evidence that a relationship between T. gondii titer and depressive symptoms exists. There is also evidence suggesting a protective effect of RhD positive blood factor on toxoplasma-induced behavioral and personality changes. This protective effect may influence the relationship between T. gondii and prenatal depressive symptoms. The purpose of this secondary data analysis was to examine the possible protective effect of RhD positive blood factor on prenatal depressive symptoms in 56 pregnant women with T. gondii infection. The cross-sectional design was utilized to answer the question “Does positive RhD blood factor provide a protective effect on prenatal depressive symptoms of patients infected with T. gondii when controlling for ethnicity, race, income, marital status, age and stress?” The conceptual model hypothesized that there was a relationship between socio-demographic variables (age, income, marital status, race, and ethnicity), stress, positive T. gondii titers, RhD positive blood factor, and prenatal depressive symptoms. Pearson correlations and multiple regression were utilized to explore the aims of this study demonstrated in the four statistical models. Significant relationship between stress and positive T.gondii seropositivity on prenatal depressive symptoms was identified. There was no significant relationship identified between RhD positive blood factor on the pregnant women infected with T. gondii which could be attributed to the small sample size.
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Foxcroft, Zyta Krystyna. "Assessment of the accuracy of pre-natal rhesus D typing on amniotic fluid using the polymerase chain reaction technique." Thesis, 2014. http://hdl.handle.net/10210/10654.

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M.Tech. (Biomedical Technology)<br>Despite the introduction of prophylactic treatment for Rh negative females, Rhesus Haemolytic Disease of the Foetus and Newborn (HDN) remains a problem. The serological diagnosis of this disease is mainly by maternal antibody identification and titration and the estimation of the optical density deviation (ODD) at 450 nanometers of the amniotic fluid. The correlation of these two results is not always good. The advent of molecular biology techniques such as the Polymerase Chain Reaction (PCR) and the sequencing of genes heralded the start of prenatal diagnosis of genetically inherited diseases and also enabled the prediction of the Rhesus group of the foetus. It would be advantageous to be able to predict with certainty the RhD status of a foetus suspected of having HDN without subjecting the mother and foetus to the risk of multiple invasive procedures such as Chorionic Villus Sampling (CVS) and Foetal Blood Sampling(FBS). The amniocentesis performed initially on a mother suspected of carrying an affected foetus would provide the sample necessary for the extraction of foetal DNA for prenatal Rh determination. Two PCR assays were used to determine the RhD group of the foetus: one using two primers amplifying a section ofIntron 4 and the other using four primers, two specific for Exon 7 and two specific for Exon 10 of the Rh gene. In 85.7% (18/21 cases) there was complete correlation between the molecular and the serological methods for RhD determination. One White foetus presented a unique profile, that of RhD negative in both molecular assays and RhD positive serologically. In the non-White group there were discrepancies between the two molecular methods as well as between the molecular and the serological methods used. This study shows that great care should be taken in the interpretation of RhD status prenatally using molecular biology techniques especially in the non-Caucasian population of South Africa in which there are many polymorphisrns in the Rhesus blood group system. For the moment, the results should be used in conjunction with serological results and clinical parameters for the diagnosis and treatment of Rh HDN.
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Silva, Catarina Marçal da. "Single Nucleotide Polymorphisms associated with venous thromboembolism - Factor XI, ABO blood group and Fibrinogen loci – Evaluation in a Portuguese population group." Master's thesis, 2017. http://hdl.handle.net/10316/82104.

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Trabalho de Projeto do Mestrado Integrado em Medicina apresentado à Faculdade de Medicina<br>Introdução: O Tromboembolismo venoso (TEV) é uma doença que resulta da interação de fatores de risco genéticos e adquiridos. Com o desenvolvimento dos Genome wide association studies (GWAS), foi possível demonstrar a associação do TEV com loci de suscetibilidade comuns ou de baixa frequência que podem ajudar a explicar a heritabilidade do TEV. De entre as variantes de risco destacam-se os alelos de risco de três single nucleotide polymorphisms (SNPs), alelo T do ABO rs2519093, alelo C do F11 rs2036914 e alelo T do FGG rs2066865, que nunca foram testadas na população portuguesa. Como tal, este estudo pretende avaliar a frequência dos três alelos de risco nos loci ABO, F11 e FGG e averiguar a associação com o risco de TEV numa amostra populacional Portuguesa.Metodologia: Realizou-se um estudo caso-controlo retrospetivo com 95 casos de TEV sem fatores genéticos ou adquiridos de elevado ou moderado risco (2012-2015) e 132 controlos saudáveis de origem Portuguesa. Os SNP’s F11 rs2036914 e FGG rs2066865 foram genotipados utilizando PCR em tempo real com sondas TaqMan. O SNP ABO rs2519093 foi genotipado por restriction fragment length polymorphism (RFLP) recorrendo à enzima de restrição DdeI. Foram estimadas as frequências alélicas, avaliada a conformidade com o equilíbrio Hardy-Weinberg e testada a associação entre os loci em estudo e o risco de TEV por regressão logística através do cálculo do OR (odds ratio), intervalos de confiança (IC) de 95% e valores de p, recorrendo ao software PLINK. A associação entre o número cumulativo de alelos de risco e o risco para TEV foi calculado através do teste de χ2 de Pearson utilizando o programa Simple Interactive Statistical Analysis (SISA).Resultados: Na população estudada, as frequências alélicas estimadas do alelo de risco foram: 0,194 para FGG rs2066865 (alelo T), 0,63 para o F11 rs2036914 (alelo C) e 0,302 para ABO rs2519093 (alelo T). O teste de regressão logística no modelo aditivo mostrou que o polimorfismo FGG rs2066865 se encontra associado ao risco de TEV (nominal p=0,02; OR=1,71, IC 95% 1,08-2,69) e o polimorfismo ABO rs2519093 aproximou-se de níveis marginais de significância estatística (nominal p=0,087 ajustado à idade e sexo, OR=1,42, IC 95% 0,93-2,16) para TEV. O loci F11 rs2036914 não mostrou associação estatisticamente significativa ao risco de TEV (p=0,64). Observou-se igualmente um aumento do risco para TEV associado a um número cumulativo de alelos de risco (0 vs. 2 ou mais alelos de risco: χ2=5,50, p=0,019, OR=2,31).Conclusões: Os resultados obtidos sugerem que o alelo de risco T do SNP FGG rs2066865 e do ABO rs2519093 contribuem para o risco de TEV nesta amostra da população Portuguesa, individual e cumulativamente.<br>Background: Venous Thromboembolism (VTE) is a disease resulting from the interactions of inherited and non-inherited risk factors. Genome wide association studies (GWAS) enable the association between VTE and common or low-frequency susceptibility loci, which can explain the heritability of VTE. From the risk variants, there are three single nucleotide polymorphisms (SNP) ABO rs2519093 (allele T), F11 rs2036914 (allele C) and FGG rs2066865 (allele T) that have not yet been assessed in the Portuguese population. Therefore, we intend to evaluate the frequency of these three risk alleles and to assess the association between risk alleles in the ABO, F11, FGG loci and the risk of VTE.Materials and Methods: A retrospective case-control study was conducted with 95 cases of VTE without strong or moderate inherited or non-inherited predisposing factors (2012-2015) and 132 healthy controls of Portuguese origin. F11 rs2036914 and FGG rs2066865 SNP’s were genotyped by real-time PCR with TaqMan probes. ABO rs2519093 SNP was genotyped by restriction fragment length polymorphism (RFLP) with DdeI restriction enzyme. PLINK software was used to determine the allelic frequencies, concordance with Hardy Weinberg equilibrium and association between risk alleles and VTE through logistic regression estimating OR with 95% confidence intervals (95% CI) and p-values. The association between the cumulative number of risk alleles and the risk of VTE was assess through Pearson χ2 using the Simple Interactive Statistical Analysis software (SISA).Results: In the analyzed population, the estimated risk allele frequencies were: 0.194 for FGG rs2066865 (allele T), 0.63 for F11 rs2036914 (allele C) and 0.302 for ABO rs2519093 (allele T). The logistic regression under an additive model showed that FGG rs2066865 was associated with VTE (nominal p=0.02; OR=1.71, CI 95% 1.08-2.69) and ABO rs2519093 attained near marginal significance in the association with VTE (nominal p=0.087 adjusted for age and sex; OR=1.42, IC 95% 0.93-2.16). F11 rs2036914 never reach statistical significant association with VTE p=0.64). In addition, there was an increased risk of VTE associated with the increment in the total number of risk alleles (0 vs. 2 or more risk alleles: χ2=5.50, p=0.019, OR=2.31).Conclusion: The obtained results suggest that the risk allele T of FGG rs2066865 and ABO rs2519093 SNPs contribute to the VTE risk (individually and additively) in this Portuguese population sample.<br>Outro - O Centro de Investigação em Antropologia e Saúde (CIAS) – Universidade de Coimbra financiou os reagentes necessários para a metodologia desta investigação
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Warren, C. Peter W. "The birth of a medical research programme. the Rhesus (Rh) factor studies, Dr. Bruce Chown, and the Faculty of Medicine, University of Manitoba, 1883-1946." 2011. http://hdl.handle.net/1993/4930.

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The thesis is an analysis of the birth of the Rhesus (Rh) Factor Research Programme in the Faculty of Medicine, University of Manitoba. Rh Factor is one of the blood groups which can lead a pregnant mother to react to her baby’s blood and destroy it. Research on this disorder yielded one of Manitoba’s most profound medical discoveries. The account reveals that three elements contributed to this research, namely the researcher, the circumstances and chance. The narrative identifies the researcher, Dr. Bruce Chown, as a major influence in the development of the Faculty of Medicine, University of Manitoba. The conditions nationally and locally that enabled him to succeed in his research are examined. The role of chance in his picking a research subject is considered. The story of Bruce Chown and the start of the Rh research illustrates the beginnings of medical research in Manitoba. The primary sources for the study were the Archives of the University of Manitoba, Archives Manitoba and the National Archives Ottawa.
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Books on the topic "ABO and Rhesus factor"

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Whitelaw, Sonny. The Rhesus Factor. Double Dragon Publishing, 2005.

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The Rhesus factor: Current concepts. Jaypee, 2002.

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(Editor), Doris Teichler Zallen, D. A. Christie (Editor), and E. M. Tansey (Editor), eds. The Rhesus Factor And Disease Prevention. Wellcome Trust Centre for the History of Medi, 2004.

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Clarke, Cyril A. Rhesus Haemolytic Disease: Selected Papers and Extracts. Springer London, Limited, 2012.

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Clarke, Cyril A. Rhesus haemolytic disease: Selected papers and extracts. Springer, 2012.

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Lockyer, W. John. Essentials of ABO -Rh Grouping and Compatibility Testing: Theoretical Aspects and Practical Application. Elsevier Science & Technology Books, 2014.

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BROWN, Lipps. Women in Relationships: Understanding Your Genotype, Requirement for a Woman to Know Her Rhesus Factor Before Marriage, Habits of Pregnant Women and Getting a Piercings While Pregnant. Independently Published, 2022.

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Smith, Alison. Transfusion of blood products. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199642663.003.0011.

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The transfusion of blood products may be required in the pre- and post-operative periods. However, there are inherent risks associated with blood transfusion, and there is not an unlimited supply of blood donations available. When a patient is anaemic, red blood cells should be transfused to maintain the oxygen-carrying capacity of blood. Blood products, such as platelets and fresh frozen plasma, are transfused to correct a coagulopathy and during major haemorrhage. This chapter reviews the physiology of blood, including ABO compatibility and rhesus status, the main blood products available for transfusion, and transfusion policy, including the treatment of major haemorrhage and the refusal of blood products.
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The Rhesus factor and disease prevention : the transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 3 June 2003. London: Wellcome Trust Centre for the History of Medicine at UCL, 2004.

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McCann, Shaun R. Blood and the hidden virus. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198717607.003.0005.

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A major achievement in the history of blood transfusion was discovery of the rhesus blood groups. The work of Philip Levine and Rufus Stetson led to the discovery of the Rh factor and its relevance to haemolytic disease of the newborn. Later developments led to the generation of the anti-Rh (anti-D) antibodies. The chapter goes on to discuss the contamination of anti-D blood products with hepatitis C and the subsequent isolation of the hepatitis C virus. The contamination of donated blood products by hepatitis C and variant Creutzfeldt–Jakob disease is discussed, with specific relevance to the practice of blood donation and screening processes.
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Book chapters on the topic "ABO and Rhesus factor"

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Cotton, Bryan A., and Laura A. McElroy. "Rhesus Factor." In Encyclopedia of Trauma Care. Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-29613-0_85.

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"The ABO and Rhesus Systems." In Clinical Transfusion Medicine. CRC Press, 1999. http://dx.doi.org/10.1201/9781498713818-11.

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"Chapter^>26: ABO Blood Group System." In Erythrocytes of the Rhesus and Cynomolgus Monkeys. CRC Press, 2015. http://dx.doi.org/10.1201/b19221-30.

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Hernaningsih, Yetti. "ABO Blood Group and Thromboembolic Diseases." In Blood Groups - More Than Inheritance of Antigenic Substances [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.102757.

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Thromboembolic diseases are usually inherited in the family. The tendency to repeat in an individual is a phenomenon that allows it to be studied. The inheritance and recurrence of thromboembolic diseases, of course, have individual risk factors for this occurrence. In the past, the ABO blood group was only needed for transfusion and organ transplant therapy. Over time, scientists think that blood type is a risk factor for certain diseases, including thromboembolism. Many studies divide between type O and non-O blood groups, both of which are distinguished by the presence of antigens on the cell surface and antibodies in the plasma of individuals. Type O does not have A, B antigens but has antibodies against A, B antigens, and vice versa for the non-O type. Many studies have shown that the non-O blood group has a risk factor for thromboembolic diseases, commonly due to higher levels of von Willebrand factor (VWF) and factor VIII (FVIII). These thromboembolic events can occur in arteries or venous. Thromboembolic manifestations are often associated with cardiovascular diseases for arterial thrombosis; and deep vein thrombosis (DVT) and pulmonary embolism (PE) for venous thromboembolism (VTE).
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Eyre, Toby. "Blood product support." In Oxford Handbook of Cancer Nursing, edited by Mike Tadman, Dave Roberts, and Mark Foulkes. Oxford University Press, 2019. http://dx.doi.org/10.1093/med/9780198701101.003.0038.

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This chapter covers the use of blood products for patients with cancer. Issues of compatibility, ABO grouping, and rhesus are all discussed. The use of red cell transfusions is explored, covering up-to-date guidelines on their use. Transfusion reactions and their management are also described. The chapter then explores the use of platelet transfusions, as well as commonly seen reactions. There is also a look at specialized aspects of blood product use, including cytomegalovirus testing and irradiated blood products for immunocompromised patients. The final section looks specifically at the nurse's role, including patient education, safety checking, and patient monitoring.
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Allison, Gillian L. "Haematology." In Therapeutics and Human Physiology. Oxford University Press, 2013. http://dx.doi.org/10.1093/hesc/9780199655298.003.0009.

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This chapter examines the significance of haematology. It defines haematology as a branch of medicine that is involved with the study of blood, blood-forming organs, and blood diseases. Haematology is also about their prevention and treatment. The process of haemostasis prevents excessive loss of blood and is essential for maintaining life. Blood disorders can arise from defects in blood vessels or from abnormalities in the blood itself and include bleeding disorders, platelet disorders, haemophilia, and anaemia. The chapter explores the ABO and rhesus (Rh) systems and shows that they are the most important blood groups used for blood typing for transfusion since not all blood groups are compatible and eventually lead to agglutination.
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Stachur, Christina. "Use of Uncrossmatched Products." In Advanced Anesthesia Review, edited by Alaa Abd-Elsayed. Oxford University PressNew York, 2023. http://dx.doi.org/10.1093/med/9780197584521.003.0182.

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Abstract Certain clinical situations, such as massive hemorrhage, necessitate transfusion of blood products before crossmatched blood is available. This chapter describes why uncrossmatched blood products are used and what type of uncrossmatched products are commonly used. Uncrossmatched products are used in situations where a patient’s ABO blood group is unknown, and the patient requires a life-saving transfusion that cannot wait for crossmatched blood to be prepared. The risks and benefits of using uncrossmatched packed red blood cells (pRCBs), plasma, and whole blood are covered, as well as how Rhesus status affects selection and transfusion of products. Finally, it describes the clinical markers anesthesia providers should be wary of in cases of transfusion reaction.
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"Blood transfusions, blood groups, the rhesus factor and haemoglobinopathies." In The History of Obstetrics and Gynaecology. CRC Press, 2000. http://dx.doi.org/10.1201/b14682-6.

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Azanjac Arsic, Ana. "ABO Blood Groups and Risk of Glioma." In Blood Groups - More Than Inheritance of Antigenic Substances [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.100566.

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Gliomas are one of the most common primary brain tumors and the etiology of gliomas remains unknown in most cases. The aim of this case–control study was to investigate possible association between incidence in relation to glioma and certain blood groups. This study included 100 histopathologically verified cases of glioma and 200 age and sex-matched controls without malignant diseases that were admitted to the same hospital. The results revealed that the patients with group AB were at 3.5-fold increased risk of developing glioma compared to the patients with other ABO blood groups. In this particular study, there was more male patients with glioma with the blood group AB. However, mechanisms that explain the relationship between the blood groups ABO and a cancer risk are unclear. Several hypotheses have been proposed, including the one with a modulatory role of blood group ABO antigens. In addition, the blood group ABO system regulates the level of circulating proinflammatory and adhesion molecules which play a significant role in the tumorigenesis process. Additionally, the recent discovery that includes the von Willebrand factor (vWF) as an important modulator of angiogenesis and apoptosis provides one plausible explanation as regards the role of the blood group ABO in the tumorigenesis process. To our knowledge, this is the first study that examined the relationship of blood group in patients diagnosed with glioma among the Serbian population. Moreover, for the first time our study results suggested that blood group AB increased the risk of glioma. The results of this study suggested that the blood group AB could be one of hereditary factors which had an influence on the occurrence of glioma. The further research is needed on a larger sample, to confirm these findings and the possible mechanisms by which the ABO system contributes to the pathology of glioma.
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Kumpel, Belinda M. "Human monoclonal antibodies to blood group antigens." In Monoclonal Antibodies. Oxford University PressOxford, 2000. http://dx.doi.org/10.1093/oso/9780199637232.003.0005.

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Abstract Many human alloantigens on red blood cells are not recognized by the mouse immune system, and therefore murine monoclonal antibodies to many desired blood group specificities cannot be produced using conventional murine hybrid oma technology. Among these is the Rh (rhesus) D antigen, which is the most immunogenic of the blood group alloantigens and clinically is the most import ant after the ABO blood groups. Most human monoclonal blood group antibodies have been made to the Rh D polypeptide. Monoclonal anti-D has been produced to replace or supplement plasma-derived anti-D for blood grouping (1) and for therapeutic Rh D prophylaxis for prevention of haemolytic disease of the new born (2). Also, there are more individuals with high titre anti-D than with anti bodies to other blood groups, who can donate source material. For this reason, the methods described in this chapter are those that have been used for the production of monoclonal anti-D.
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Conference papers on the topic "ABO and Rhesus factor"

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Phan, A. T., A. Ucar, A. Tseng, et al. "ABO Blood Group and Rhesus Factor Association With COVID-19 Mortality and Severity: A Two-year Retrospective Review." In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a1647.

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Ørstavik, K. H., L. Kornstad, and H. M. Reisner. "LEWIS BLOOD TYPE HAS AN EFFECT ON THE PLASMA CONCENTRATION OF FACTOR VIII." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644062.

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The plasma concentration of factor VIII is influenced by the ABO blood group. Individuals with blood group 0 have a lower concentration of both factor VIII coagulant activity, factor VIII coagulant antigen (VIIICAg) and factor VIII related antigen (VIHRAg) than individuals with group A, B and AB. Thirty percent of the genetic variance of VIIIRAg concentration is due to the ABO blood group. The Lewis substances Lea and Leb are closely related to the A, B and H substances. We therefore examined the effect of the presence of these antigens on the plasma concentration of VIIICAg and VIIIRAg. The material was 74 monozygotic and 84 dizygotic twin pairs and 58 blood donors with ABO blood group 0. VIIICAg was determined by a radioimmunoassay and VIIIRAg was determined by an electroimmunoassay. A higher mean concentration °f VIIICAg (147%) and VIIIRAg (81%) was found in individuals with the Le antigen on their red cell surface compared to the mean concentration of VIIICAg (101%) and VIIIRAg (66%) in individuals who lacked this antigen. The difference was found in individuals with ABO blood group 0 only. Individuals with red cell Lea antigen are non-secretors and individuals who lack this antigen but have the Leb antigen are secretors of the A, B and H substances. The lowest factor VIII concentration was found in group 0 secretors. The effect of the Lewis phenotype on factor VIII concentration is therefore most probably due to an effect of the secretor locus. This finding may have practical implications for the diagnosis of carriers of hemophilia A. it has been shown that information on the ABO blood group improves the discrimination between carriers and normals. We found that the effect of ABO blood group on the total variance of VIIIRAg was higher in secretors (21%) than in non-secretors (8%). Since the frequency of secretors varies widely, it is possible that the importance of the ABO locus in carrier detection is different in different populations. Lewis blood typing in materials of carriers and normals are necessary to determine the effect of the Lewis phenotype in carrier detection.
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Schulze, Arik Bernard, Lars Henning Schmidt, Lara Baie, et al. "Rhesus CE expression is an independent prognostic factor in non-small cell lung cancer." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa2865.

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Bonk, M., E. Kotloff, M. G. S. Shashaty, et al. "ABO Blood Type as a Risk Factor for Disseminated Intravascular Coagulation (DIC) in Sepsis." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7166.

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Hathaway, A., G. Qian, J. King, et al. "P152 The association of ABO and Rhesus blood group with severe outcomes from non-SARS CoV-2 respiratory infection: a prospective observational cohort study 2020–2022." In British Thoracic Society Winter Meeting 2023, QEII Centre, Broad Sanctuary, Westminster, London SW1P 3EE, 22 to 24 November 2023, Programme and Abstracts. BMJ Publishing Group Ltd and British Thoracic Society, 2023. http://dx.doi.org/10.1136/thorax-2023-btsabstracts.303.

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Norden, C., H. Heine, F. Misselwitz, H.-J. Herrmann, E. Engler, and G. Martin. "PLATELET AND VESSEL WALL REACTIVITY IN HYPERTENSIVE AND N0RM0TENSIVE RHESUS MONKEYS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644497.

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Hypertension is an important risk factor in the pathogenesis of arteriosclerosis and its thrombotic complications. Therefore, we investigated platelet and vessel wall reactivity in 7 subhuman primates (7.0 Macaca mulatta). Five monkeys received a psychosocial stress over a long-term period, three developed a stress-induced hypertension. Two unstressed normotensive monkeys served as e control. Platelet turnover in vivo, synthesis of platelet prostanoids, and various platelet function tests in vitro were determined. Vessel wall reactivity was assessed histo-pathologically and by means of H-thymidin-incorpora-tion into vessel segments in vitro. In the hypertensive rhesus monkeys an accelerated platelet turnover, accompanied with a decreased platelet count, and a markedly increased plasma-TXB2-level were found. ADP-induced platelet aggregation was slightly enhanced. Additionally, platelet adhesion to collagen-coated surfaces was investigated. We found the platelet attachment, spreading, and the formation of platelet mural thrombi to be significantly enhanced in the hypertensive animals. Histopathological examination of large arteries revealed signs of an increased intra-vital vasocontraction as well as enlargement of the relative vessel wall cross-section area in the hypertensive rhesus monkeys. Autoradiographical determination of the thymidine-incorporation in vitro allows investigation of cell proliferation in the intima and media of vessels. We found hypertension-related alterations of the media not only in large, but also in small vessels. Additionally, primary cultures of aortic endothelial cells were established and concentration of endothelial cell-specific metabolites was measured in the conditioned media. Our results confirm the existence of hypertension-related changes in platelet and vessel wall reactivity.
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Scheiner, B., PG Northup, AB Gruber, et al. "The impact of ABO blood type on VWF and factor VIII levels and the prevalence of portal vein thrombosis in patients with advanced chronic liver disease." In 52. Jahrestagung & 30. Fortbildungskurs der Österreichischen Gesellschaft für Gastroenterologie & Hepatologie (ÖGGH). Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1691902.

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Reports on the topic "ABO and Rhesus factor"

1

Geisbert, Thomas W., Lisa E. Hensley, Peter B. Jahrling, Tom Larsen, and Joan B. Geisbert. Treatment of Ebola Virus Infection With a Recombinant Inhibitor of Factor Vlla/Tissue Factor: A Study in Rhesus Monkeys. Defense Technical Information Center, 2003. http://dx.doi.org/10.21236/ada430462.

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