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Boycheva, Maria. "BLOOD-GROUP ABO AND RHESUS FACTOR SYSTEMS DISTRIBUTION IN INDIVIDUALS OF VIETNAMESE NATIONALITY." Journal Scientific and Applied Research 12, no. 1 (2017): 74–78. http://dx.doi.org/10.46687/jsar.v12i1.229.
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The article reports the results of a study of blood group ABO and Rhesus factor systems conducted on 423 Vietnamese citizens (104 men and 319 women) aged 19 to 77 who lived or are currently living in Bulgaria. The frequency of the individual groups of the AB0 system is: 0 - 49,88%, B - 25,06%, A - 21,75%, AB - 3,31%, and the gene frequency - r = 0,711, q = 0,155, p = 0.134. Only subsets A1 and A1B were detected in the ABO system. There was only Rh in the studied population.
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Onah, Ikechukwu Eugene, Ezinne Veronica Moses, Ifeyinwa Esther Ugwuoke, Sabina Chioma Eze, Jude Ifeanyichukwu Okwor, and Patience Obiageli Ubachukwu. "Comparative ABO blood group and rhesus factor distribution between homogenous and heterogenous populations in South Eastern Nigeria." Asian Journal of Medical Sciences 10, no. 5 (2019): 37–42. http://dx.doi.org/10.3126/ajms.v10i5.25013.
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Background: The ABO blood group and Rhesus (Rh) factor remain the most important blood group in transfusion medicine. Knowledge of ABO and rhesus blood group distribution within a population is indispensable for transfusion medicine, clinical and marriage counselling.
 Aims and Objectives: The objectives of this study were to provide data and compare the pattern of ABO and rhesus blood group distribution between a homogenous and a heterogenous population.
 Material and Methods: Blood was collected from 352 University students representing a heterogenous population and 235 primary school pupils in a local community representing homogenous population. The ABO and rhesus blood groups were determined using white tile and agglutination methods.
 Results: Among the 352 and 235 individuals studied in UNN and HFNP, blood groups O had the highest frequency with 54.80% and 51.06% respectively while blood group AB had the least frequency of 4.50% and 3.40% in UNN and HFNP respectively. Rhesus positive had the highest frequency of 88.63% and 95.33% while rhesus negative had the frequencies of 11.35% and 4.68% in UNN and HFNP respectively. Rhesus negative was highest among females in UNN 26 (7.37%) while males had the highest rhesus negative 7 (2.98%) in HFNP. In both study populations, there was no significant difference in ABO and rhesus blood group distribution between the males and females (P > 0.05).
 Conclusions: A homogenous population is associated with low prevalence of rhesus negative compared to a heterogenous population.
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Bamou, Roland, and Silas L. Sevidzem. "ABO/Rhesus blood group systems and malaria prevalence among students of the University of Dschang, Cameroon." MalariaWorld Journal 7, no. 4 (2024): 1–4. https://doi.org/10.5281/zenodo.10797079.
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<strong>Background.</strong> A study was carried out on students of the University of Dschang, Cameroon, to examine the relationship between ABO blood group, rhesus factor and prevalence of <em>Plasmodium falciparum</em> infection. <strong>Materials and methods.</strong> Blood group and rhesus factor were typed by agglutination using antisera while malaria infection was determined using Rapid Diagnostic Test CareStart malaria HRP2 pf. Out of 620 students 582 were screened for ABO blood group and Rhesus factor, and 276 were tested for <em>P. falciparum</em> infection. <strong>Results.</strong> Faculty of Science (FS) members and male students were highly represented, with 356 (61.2% ) and 303 (52.1%) participants, respectively. Blood group O was most common (48.8%), followed by blood group A (25.8%), B (23.0%) and AB (2.4%). Total percentage of rhesus positive was 92.4%, and its distribution varied across ABO blood groups. Of the 276 students examined for malaria infection, 27 were found positive (9.8%). Except for blood group AB individuals, of which none were infected, malaria infection did not vary among blood groups. <strong>Conclusion.</strong> Rhesus factor and blood group did not impact on malaria infection in the hypo-endemic highland area of Dschang, Cameroon.
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Akogu, Simon P. O., Owemidu Idowu Olumorin, and Shedrack Egbunu Akor. "Distribution of ABO, Rhesus Factor Blood Phenotype and Haemoglobin Genotype among Antenatal Clinic Attendees in Anyigba, North Central Nigeria." European Journal of Medical and Health Sciences 3, no. 6 (2021): 11–13. http://dx.doi.org/10.24018/ejmed.2021.3.6.954.
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Background: In the practice of obstetrics and gynecology, the ABO and Rhesus factor (Rh) blood type are important. Blood typing for blood transfusion of compatible blood is very common in emergency and routine care. There is a scanty literature on the distribution of ABO and Rhesus blood types in Anyigba, (North central) Nigeria. Objective: This study aims to determine the distribution of ABO blood and Rhesus blood group phenotypes and Hemoglobin genotypes among antenatal clinic attendees in a teaching hospital. Methods: Antenatal records of attendees (October 2017 to September 2020) at the Kogi State University Teaching Hospital were retrieved and results of antenatal hematological investigations were collected using a structured tool.Bio data, ABO blood group, Rhesus group phenotype and Hemoglobin genotype were collected, inputted and analyzed using SPSS version 20. Results: The mean age was 26 +/- 7years, blood group O is most prevalent,561 (53.6%) then A 276 (26.4%), B 189 (18.1%) and AB,21 (2%).1014 (96.4%) were Rhesus D positive, 33 (3.1%) were Rhesus D negative. For hemoglobin genotype, 786 (75.1%) were AA, 258 (24.6%) were AS, AC were 3 (0.3%). Conclusion: The distribution of the ABO, the Rhesus (D) blood groups and hemoglobin genotypes are in concurrence with the findings of previous studies; Blood group O is the most prevalent and AB the least prevalent, Rhesus (D) positive in the population is high and the hemoglobin genotype AA is the most prevalent. There is no association between blood group phenotypes studied and the hemoglobin genotypes.
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Dhana Reswari, Putu Ayu, Yustisia Amalia, and Renata Primasari. "Sosialisasi Sosialisasi Dan Edukasi Tentang Donor Rhesus Negatif Di Unit Tranfusi Darah PMI Kota Surabaya Tahun 2020." Jurnal of Community Health Development 3, no. 2 (2022): 16. http://dx.doi.org/10.20884/1.jchd.2022.3.2.4806.
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Abstrak Golongan darah tidak hanya dapat dibedakan menjadi A, B, AB, atau O menurut sistem ABO, tetapi juga melalui sistem faktor Rhesus (Rh). Komponen ini diperiksa dalam pemeriksaan golongan darah. Faktor rhesus dilihat dari keberadaan protein bawaan pada sel darah merah. Meskipun populasi rhesus negatif secara keseluruhan didominasi oleh orang-orang Kaukasia, rhesus negatif juga ditemukan di orang-orang Asia, tak terkecuali Indonesia. Menurut Badan Pusat Statistik (BPS), pada tahun 2010 populasi rhesus negatif di Indonesia tidak mencapai angka 1 % (sekitar 1,2 juta orang). Secara alami, gen pembawa rhesus negatif bersifat resesif, sedangkan rhesus positif bersifat dominan maka jumlah orang dengan rhesus negatif menjadi lebih sedikit. Pengabdian Masyarakat ini bekerja sama dengan Unit Tranfusi Darah (UTD) PMI Kota Surabaya dalam bentuk Sosialisasi dan Edukasi Tentang Donor Rhesus Negatif Di PMI Kota Surabaya agar warga masyarakat awam pun mengerti bahwa golongan darah tidak hanya A,B,AB dan O tetapi juga ada rhesus terutama tentang rhesus negatif. Kata Kunci : Rhesus Negatif, Golongan darah, ABO Abstract Blood types can not only be distinguished into A, B, AB, or O according to the ABO system, but also through the Rhesus (Rh) factor system. This component is examined in the blood group examination. The rhesus factor is seen from the presence of an innate protein in red blood cells. Although the overall rhesus negative population is dominated by Caucasians, rhesus negative people are also found in Asian people, including Indonesia. According to the Central Statistics Agency (BPS), in 2010 the rhesus negative population in Indonesia did not reach 1% (about 1.2 million people). Naturally, the gene carrying rhesus negative is recessive, while rhesus positive is dominant, so the number of people with rhesus negative becomes less. This Community Service collaborates with the Blood Transfusion Unit (UTD) of PMI Surabaya City in the form of Socialization and Education About Rhesus Negative Donors at PMI Surabaya City so that ordinary people understand that blood types are not only A, B, AB and O but there is also Rhesus especially about rhesus negative. Keywords: Rhesus Negative, Blood type, ABO
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Abuladze, Salome, Leila Akhvlediani, Marina Nagervadze, et al. "ABO Blood Groups, Rhesus Factor, and Rheumatoid Arthritis." Theoretical and Natural Science 67, no. 1 (2024): 30–36. https://doi.org/10.54254/2753-8818/2024.18063.
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The ABO and Rhesus blood group systems play critical roles in clinical practice, particularly concerning their associations with autoimmune diseases, including rheumatoid arthritis (RA). This study aimed to investigate the relationship between ABO blood types, Rh factors, and RA in a Georgian population. A total of 157 participants were included, comprising 93 RA patients and 64 healthy controls. Blood samples were analyzed for ABO and Rh D blood group determination, revealing that blood type O was the most prevalent among RA patients (50.5%), followed by type A (35.5%), while the control group exhibited similar distributions (O: 54.7%, A: 34.4%). The Rh factor analysis indicated a slightly higher prevalence of Rh-positive individuals in the RA group (84 patients) compared to Rh-negative individuals (9 patients). The overall distribution of blood types in RA patients closely mirrored that of the general population, indicating no significant link between ABO blood types and RA. Further research is warranted to explore these associations and their implications for RA pathogenesis and potential therapeutic targets.
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Valikhani, Mahin, Sima Kavand, Siavash Toosi, Golnaz Kavand, and Maryam Ghiasi. "ABO blood groups, rhesus factor and pemphigus." Indian Journal of Dermatology 52, no. 4 (2007): 176. http://dx.doi.org/10.4103/0019-5154.37720.
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Maha, Tareq Hussein. "Study of blood groups and Rhesus factor in beta thalassemia patients undergoing blood transfusions." International Journal of Biomolecules and Biomedicine (IJBB) 13, no. 6 (2021): 1–6. https://doi.org/10.5281/zenodo.8332093.
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Beta thalassemia is the most common genetic blood disease, affecting millions of people in both developing and developed countries including Iraq. Patients with thalassemia require frequent blood transfusions, which can cause a variety of complications. Several researches have looked into the link between ABO blood groups and diseases. The associations of ABO blood group with thalassemia have not been extensively studied. In order to know the prevalence of thalassemia according to age, gender and blood group frequency, a study was conducted on 200 individuals, 100 of them were a control sample, which was considered a standard sample, while the rest 100 individuals were infected with beta thalassemia. The study aims to find out any relationship between the frequency of blood group phenotypes and susceptibility to thalassemia compared to the control sample. Our findings indicate that the prevalence of thalassemia was higher in female patients than in male patients. Found in the lowest age group 15-19 years. There was a significant difference (P 0.05) in the frequency of ABO blood groups that was O > B > A > AB. A significant difference of Rh factor (P<0.01) was found in the patients compared with the control group. The current study indicated the importance of the studied blood groups, as they are sources for detecting the risks of inheriting beta thalassemia or the variability in the likelihood of its appearance, and they can be used with other laboratory tests in genetic counseling. Published by the <strong>International Journal of Biomolecules and Biomedicine (IJBB)</strong>
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Perepelitsa, S. A., V. A. Sergunova, S. V. Alekseeva, and O. E. Gudkova. "ERYTHROCYTE MORPHOLOGY IN NEONATAL RHESUS FACTOR AND ABO ISOIMMUNIZATION." General Reanimatology 11, no. 2 (2015): 25. http://dx.doi.org/10.15360/1813-9779-2015-2-25-34.
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Edibamode, Ezon-Ebidor Innocent, Edet Iboro Efiong, Nicholas Asiwe, and Cynthia Eben Gobour. "Factors Related to Premature Canities; A Cross-sectional Study in Lagos State, Nigeria." Asian Journal of Advanced Research and Reports 18, no. 5 (2024): 144–55. http://dx.doi.org/10.9734/ajarr/2024/v18i5642.
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Background: Canities, or graying or whitening hair, is a natural part of aging caused by reduced melanin production. Premature canities occur in humans or animals at a young age, with factors such as genetics, lifestyle, and environmental influences contributing. The study aims to evaluate the relationship between ABO Blood type, rhesus Factor, Genotype, Lifestyle, and Premature canities.
 Methods: 259 respondents were involved and a cross-sectional descriptive study design was used to generate data. The respondents were selected using a multi-stage random sampling techniques and data collection was via descriptive questionnaire. Data obtained were analyzed using IBM SPSS version 25.
 Results: A study of 259 participants found no significant association between premature canities and ABO blood type, rhesus, and genotype while lifestyle factors like smoking, and alcohol intake showed an association. Canities were found in various head regions, with no differences between sexes. Smoking and alcohol intake were more common in males. Depression was negatively associated with non-premature and premature canities. Nutrition intake was similar, but high carbohydrate and vegetable consumption was found to be statistically different.
 Conclusion: No association between ABO blood type, rhesus factor, genotype with premature canities, and lifestyle (alcohol intake and smoking) showed possible association with premature canities.
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Sequi-Canet, Jose Miguel, Jose Miguel Sequi-Sabater, Jose Ignacio Collar-Castillo, and Nelson Orta-Sibu. "Are ABO Blood Groups or Rh Antigen Perinatal Factors Affecting the Pass Rate of Transient Otoacoustic Emissions Screening Tests in Healthy Newborns during the First 48 h of Life?" International Journal of Neonatal Screening 5, no. 1 (2019): 4. http://dx.doi.org/10.3390/ijns5010004.
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Most hospitals recommend performing neonatal hearing screening. Transient evoked otoacoustic emission (TEOAE) tests represent an ideal technique for conducting this process. Previous studies have related the influence of ABO blood group and Rhesus antigens (Rh) on the susceptibility to various pathologies. However, available data about the potential relationship between ABO blood groups, Rh, and TEOAE pass rates are sparse. Recently, several authors concluded that O blood group and Rh+ are possible influential factors of TEOAE pass rates. Significantly different TEOAE amplitude response between the four main ABO blood groups were observed among normal-hearing individuals. Moreover, ABO blood groups were discussed as a possible influential factor for the development of noise-induced hearing loss later in life. The aim of this study was to investigate the relationship between ABO blood groups, Rh, and the first TEOAE pass rates in healthy newborns. Data were retrospectively collected from healthy newborns at the maternity ward of F. Borja hospital in Gandia (Spain). Rh and ABO were compared with the results of TEOAE performed within the first 48 h of life. Results: the study group included 2765 newborns. No significant correlation between ABO blood group or Rh and TEOAE pass rates was observed in comparative tables. Conclusion: ABO blood group and Rhesus antigens do not appear to have a significant impact on the pass rate of TEOAE screening in healthy newborns.
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Adegoke AO, Amole IO, Adesina SA, et al. "Distribution of ABO-Rh(D) blood group among nursing students: A tool for female health education." Ibom Medical Journal 17, no. 3 (2024): 548–53. https://doi.org/10.61386/imj.v17i3.517.
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Background: The International Society of Blood Transfusion has documented 30 distinct blood group systems; the ABO and Rh systems are regarded as the most important blood group systems. Determining the ABO-Rh (D) blood group is vital in clinical settings to prevent the possibility of incompatibility and Rhesus D alloimmunization. Objective: This study aimed to provide information on the distribution of blood groups and Rh factor among Bowen University Teaching Hospital School of Nursing students with the view of educating students about the risks of rhesus incompatibility. Material and Methods: retrospective cross-sectional study which reviewed the preschool entry medical records of Nursing students of Bowen University Teaching Hospital Ogbomoso from 2019-2022. The data were systematically collated, analyzed and used to generate frequency tables. Results: a total of 216 records were reviewed. The majority were females (84.3%), less than or equal to 18 years (48.6%) and with blood group O (44.4%) and rhesus positivity (94.0%). None from the male gender had an AB blood group. Prevalence of Rh(D) positive was higher among females (85.3%) while Rh(D) negative was higher among males (14.7%). There was a significant association between gender and Rhesus factor. Conclusion: the findings from this study shows that blood group O and Rh(D) positive had the highest prevalence while the blood group AB and Rh(D) negative had the lowest prevalence. Therefore, effort should be made to educate the few who could suffer adverse events from Rhesus incompatibility.
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Ahmed Khudhair Abdulridha AL-Ganimi. "The Relation between the Blood Groups, Rhesus Factor, and Breast Cancer in the Holy Karbala Governorate." University of Thi-Qar Journal of Science 7, no. 2 (2020): 31–33. http://dx.doi.org/10.32792/utq/utjsci/v7i2.707.
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The distribution ABO blood groups among patients with breast cancer were as follow: blood group type O (40.8%), blood group type A (25.0%), B (23.7%), and AB (10.4%), for the donor’s healthy control, ABO blood groups percentages were as follow: type O (39.9%) type A (28.1%), type B (22.0%), and type AB (9.9%). There is no significant association between blood types ABO and the breast cancer. (P > 0.05) Rh factor has a significant difference between patients with breast cancer and healthy control (P=0.002). There were significant differences in age categories among patients with breast cancer and controls. (p= 0.000) .
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SHRESTHA, SHAILAZA. "Case control study of ABO blood group and Rhesus (Rh) factor in type 2 Diabetes Mellitus." Indian Journal of Applied Research 4, no. 4 (2011): 1–312. http://dx.doi.org/10.15373/2249555x/apr2014/196.
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Kumar, PoojaVijay, M. Vanishree, K. Anila, Santosh Hunasgi, SriSujan Suryadevra, and Swetha Kardalkar. "Determination of ABO blood grouping and Rhesus factor from tooth material." Journal of Oral and Maxillofacial Pathology 20, no. 3 (2016): 540. http://dx.doi.org/10.4103/0973-029x.190962.
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Voracek, Martin. "Digit Ratio (2D:4D), Abo Blood Type, and the Rhesus Factor." Perceptual and Motor Skills 107, no. 3 (2008): 737–46. http://dx.doi.org/10.2466/pms.107.3.737-746.
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VORACEK, MARTIN. "DIGIT RATIO (2D:4D), ABO BLOOD TYPE, AND THE RHESUS FACTOR." Perceptual and Motor Skills 107, no. 7 (2008): 737. http://dx.doi.org/10.2466/pms.107.7.737-746.
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Elsayed Azab, Azab, and Jbireal JM. "The Relationship between ABO Blood Groups, Rhesus Factor and Breast Cancer." Archives of Hematology and Blood Diseases 3, no. 2 (2020): 1–10. http://dx.doi.org/10.22259/2639-3581.0302001.
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Habeeb, Bushra, Tamara Ala`a, and Hayfa`a Jaber. "Study the Relationship between ABO Blood Groups and Gingivitis Disease." Kufa Journal for Nursing Sciences 4, no. 1 (2014): 216–22. http://dx.doi.org/10.36321/kjns.vi20141.2439.
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Objectives: Design this study to determine whether there was a relationship between gingival diseases and ABO blood groups. Methodology: Data were collected 1 2 9 subjects who were randomly selected students referred to the Faculty of Dentistry. The study based on periodontal condition, blood group, and medical history. The effects of blood subgroups on periodontal health, gingivitis and periodontitis were investigated separately. Results : In the present study, all the cases were first segregated into groups based on Loe and Silness indexas: group I (mild (initial) gingivitis), group II (moderate (early) gingivitis), and group III (sever (established) gingivitis), and were further divided into four grades based on Ramfjord's Periodontal Index. Blood samples were analyzed to determine blood group and Rhesus factor. Conclusions: ABO blood subgroups and Rh factor may constitute a risk factor on the development of periodontal disease. However, long-term studies are needed to make a more comprehensive assessment of the effects of ABO group on periodontal diseases.
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Kronstein-Wiedemann, Romy, Peter Bugert, Erhard Seifried, and Torsten Tonn. "Downregulation of Glycosyltransferase a Expression By miRNA-331-3p Is Mediated By the Inhibition of the Transcription Factor SP1." Blood 128, no. 22 (2016): 1247. http://dx.doi.org/10.1182/blood.v128.22.1247.1247.
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Abstract More than 100 ABO subgroup-related variations were detected in the coding region of glycosyltransferases, which may be causative for a weak blood group antigen A or B expression. Most variation in expression is explained genetically by mutations that reduce transferase activity. However, a substantial number of weak variants have not yet been explained by current methods. We recently postulated a role of miRNA in the regulation of blood group A antigen expression levels. By using different approaches, including gene array analysis, luciferase reporter assay and overexpression of glycosyltransferase specific miRNAs in primary hematopoietic stem cells (HSCs), we found that miR-331-3p directly targets glycosyltransferase A and B mRNA. Now we have been further embarking on the underlying mechanisms of miRNA and glycosyltransferase interactions and show that the effects of miR-331-3p are mediated by inhibition of transcription factor SP1, which is a major regulator of the ABO gene, thereby resulting in downregulation of blood group A antigen expression in A2O individuals by up to 80% and in A1O individuals by up to 50%. Using microRNA target prediction tools we also identified Sp1 as a potential target gene for miR-331-3p. Western blot analyses of glycosyltransferase protein expression showed that overexpression of miR-331 led to a decreased glycosyltransferase and SP1 protein expression. Further approaches with the SP1 inhibitor, mithramycin A, revealed similar results. Analysis of Aw04/O1v genotypes revealed elevated miRNA levels, thus confirming microRNAs as regulators of blood group glycosyltransferase expression. Our findings extend our understanding of blood group regulation in carriers of weak blood group variants. Involvement of miRNAs in the downregulation of ABO blood group antigen expression may also provide an explanation for observed changes of ABO antigen expression in abnormal processes such as tumorigenesis, pregnancy and aging. Furthermore, this pathway may play a role in the regulation of other blood group variants (for instance Rhesus, KELL, amongst others). Disclosures No relevant conflicts of interest to declare.
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Pałgan, Krzysztof, Zbigniew Bartuzi, and Elżbieta Chrzaniecka. "ABO blood groups, Rhesus factor, and anaphylactic reactions due to Hymenoptera stings." Annals of Agricultural and Environmental Medicine 24, no. 3 (2017): 428–30. http://dx.doi.org/10.26444/aaem/74424.
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Koregol, AratiC, M. Raghavendra, Sangamesh Nainegali, Nagaraj Kalburgi, and Siddharth Varma. "ABO blood groups and Rhesus factor: An exploring link to periodontal diseases." Indian Journal of Dental Research 21, no. 3 (2010): 364. http://dx.doi.org/10.4103/0970-9290.70804.
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Rehman, Ghani Ur. "Association of ABO Blood Grouping and Periodontal Disease: A Literature Review." Dental Journal of Advance Studies 09, no. 03 (2021): 116–20. http://dx.doi.org/10.1055/s-0041-1736487.
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AbstractAlthough the correlation between the ABO blood group and certain systematic diseases is a well-documented fact. Few studies have explored the relationship of ABO with oral disorders including periodontal diseases (PD). This literature review aimed to assess the possible association between ABO blood grouping and PD. For this purpose, we searched online databases like PubMed and google scholar with the following terms in different combinations PD, ABO blood groups, gingivitis, the prevalence of periodontitis, aggressive periodontitis, risk factors of periodontitis, Association of PD and ABO, ABO Rh factor. English version papers describing the Oral health status are covered through research that includes clinical investigations, case studies, and retrospective studies on the subject. Historic reviews, articles with unpublished data, and letters to the editors were omitted from the survey following publications. The author thoroughly checked the titles and abstracts of the papers. The complete text was thoroughly assessed, and the relevant articles were analyzed in accordance with qualifying criteria. For further original and review research, references were further reviewed. Since our targeted subject was answered by a restricted number of original research. We identified fourteen articles describing the association of ABO blood types with PD. findings of our study concluded the genetic basis of the association of ABO blood types for the development of PD. six of the research provided here showed that the blood type O can serve as a prognostic factor for the development of PD. ABO blood types and Rhesus factors can be a risk predictors in the development of PD.
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Hashim Al Qudsi, Ghaydaa, Raghed M. Jassem, and Rafida M. Al-Amiri. "The Correlation Between ABO Blood Group and Rhesus Factor in Patients with Periodontal Diseases: Review Subject." Tikrit Journal for Dental Sciences 10, no. 2 (2023): 191–96. http://dx.doi.org/10.25130/tjds.10.2.12.
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Periodontal diseases can be defined as a wide range inflammatory condition due to the infection with pathogenic bacteria grow in oral cavity affecting the supporting structure of the teeth. Local plus systemic conditions are affected the initiating and progressing of periodontal infections. Blood groups and Rh factor may play important role in periodontal illness. The aim of present study was to find if there are relation between ABO blood groups and Rhesus factor with periodontal status and if they are possible risk factors or not according to many studies that were done throughout the world.
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Toro, Giuseppe, Federica Lepore, Stefano D. Cicala, et al. "ABO system is not associated with proximal femoral fracture pattern in Southern Italy." HIP International 28, no. 2_suppl (2018): 84–88. http://dx.doi.org/10.1177/1120700018813219.
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Introduction: The mechanism that leads to a given fracture pattern is not understood. Heredity could act in this field through the ABO system. We investigated the relationship between ABO blood system and hip fracture pattern in a population from Southern Italy. Methods: Hip fractures were identified through a registry evaluation of the activity of a level I Hospital, and subsequently classified in ‘intracapsular’ or ‘extracapsular’ according to their anatomical location. Information on these patients’ ABO blood type was collected and compared with general population data from the report on blood donors of the Salerno division of Italian Blood Volunteers Association (AVIS). Results: 590 hip fractures were included (414 extracapsular, 176 intracapsular) and compared with 709 blood donors. Fractured patients presented a blood group A more often and blood group O less often than the AVIS population ( p A vs. non-A = 0.0033; p O vs. non-O = 0.0024). None of the ABO blood groups were associated with fracture pattern ( p O vs. non-O = 0.5858, p A vs. non-A = 0.409; p B vs. non-B = 0.253; p AB vs. non-AB = 0.212). The rhesus factor was not associated the fracture pattern ( p = 0.34). Conclusions: The ABO blood type could play a role as a risk factor for proximal femoral fractures, but in our population its relevance in influencing the fracture pattern is unclear.
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Kronstein-Wiedemann, Romy, Laura Schmidt, Jörn Lausen, Erhard Seifried, and Torsten Tonn. "Inhibition of the Transcription Factor RUNX1 Causes Glycosyltransferase a Repression." Blood 130, Suppl_1 (2017): 925. http://dx.doi.org/10.1182/blood.v130.suppl_1.925.925.
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Abstract Background: The ABO blood group system is unequivocally the most important in clinical transfusion medicine. Furthermore ABO is implicated in the development of a number of human diseases. The ABO antigens are not confined to RBCs but are widely expressed in a variety of human cells and tissues. Thus, ABO matching is critical not only in blood transfusion but also in cell, tissue and organ transplantation. The molecular genetic basis of the ABO system has been known since 1990. However, despite extensive investigations about regulation of ABO blood group receptor expression, the mechanism is not fully resolved. Previously we found that miRNAs plays a critical role in regulation of ABO blood group antigen. Numerous miRNAs which were up- or downregulated in RBCs of blood group O and of heterozygous genotypes as compared to homozygous genotype possess potential binding sites in the 3'UTR of several transcription factors, such as SP1 and RUNX1. Here we show that silencing of the transcription factor RUNX1 leads to downregulation of blood group A antigen. Methods: We performed knockdown experiments for RUNX1 by lentiviral gene transfer of shRNA in primary hematopoietic stem cells (HSCs) and analyzed blood group A-antigen expression using different method, including flow cytometry, western blot and qPCR. Result: Knockdown of RUNX1 in HSCs leads to a 10-20% reduction of blood group A positive erythroid cells and a 30-40% reduction of blood group A antigens per cell in differentiated RBCs. Furthermore, microarray analysis showed a significant increase of miR-215-5p and miR-192-5p in RBCs of blood group O as compared to homozygous genotype. RUNX1 is known to be a target gene for these miRNAs. Conclusion: Glycosyltransferase A and B expression is regulated by different miRNAs, via simultaneously targeting of the transcription factors SP1 and Runx1 and glycosyltransferase A and B mRNA. The knowledge of the role of microRNAs and the transcription factors SP1 and RUNX1 in the expression of blood group antigens may be extended to other blood groups (Rhesus, Kell, Duffy) and may open the door for therapeutic interventions in diseases where blood group receptors promote disease pathology. Disclosures No relevant conflicts of interest to declare.
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Jayakkodi, Gauthaman. "A STUDY ON THE PREVALENCE OF ABO BLOOD GROUPS AND RHESUS FACTOR AMONG THE GIRL STUDENTS AROUND PERAMBALUR IN TAMILNADU." International Journal of Zoology and Applied Biosciences 2, no. 5 (2017): 211–17. https://doi.org/10.5281/zenodo.1312074.
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Blood groups are genetically determined. The frequencies of ABO and Rh blood groups vary from population to population and from time to time in the same region. A study was conducted among selected Government Higher Secondary Schools of Perambalur District from December 2016 to July 2017. Blood groups of 2148 girl students from 15 schools were screened by antigen antibody agglutination method using commercially available antisera. The study revealed that the commonest ABO blood group was O with 34.64%, followed by B group with 33.75%, A with 22.39% and AB with the least % of 9.22. Rh+ type were 96.51% and Rh- type were making up to 3.49%
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Abuhaimed, Jawahir, Amina Abbas, Mohammed Bahatheg, et al. "Distribution of ABO Blood Groups and Rhesus Factor in Critical Care Patients and Its Association with Mortality and Morbidity." Blood 144, Supplement 1 (2024): 5610. https://doi.org/10.1182/blood-2024-210863.
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Background: ABO blood group and RhD factor have been associated with various health conditions, but their impact on critically ill patients remains unclear. This study aims to explore the distribution of these blood groups among critical care patients and their association with morbidity and mortality outcomes. Methods: We conducted a retrospective analysis of ICU patients at King Saud University Medical City. Patient data, including blood group, RhD status, and clinical outcomes, were collected from medical records. Statistical analyses were performed using the Kruskal-Wallis test, chi-square test, and multivariable regression models to assess associations, controlling for age and gender. Results: The study included patients from various ABO blood groups and RhD statuses. Our findings indicate no statistically significant differences in 28-day and 90-day mortality rates among the different blood groups. Other clinical outcomes, including days alive and free of invasive breathing, days alive and free of circulatory assistance, length of ICU stay, and SOFA scores, also showed no significant variations across ABO and RhD groups. The multivariable regression analysis confirmed the lack of significant associations between these blood types and mortality or morbidity outcomes. Conclusion: The study suggests that ABO blood group and RhD factor are not significant predictors of mortality or morbidity in critically ill patients. These findings highlight that other factors, such as underlying health conditions and severity of illness, are more critical in determining patient outcomes in the ICU. Further research in larger, multicenter settings is recommended to confirm these results and explore potential underlying mechanisms.
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Shakeel, Hassan Abdullah, Hamza Maqsood, Basit Ali, and Ali Raza Khan. "Association of chronic viral hepatitis with ABO blood groups and rhesus (Rh) factor." International Journal of Research in Medical Sciences 6, no. 4 (2018): 1114. http://dx.doi.org/10.18203/2320-6012.ijrms20181265.
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Background: Chronic viral hepatitis includes hepatitis B and hepatitis C and is responsible for causing the deaths of millions of people all across the world each year. Although there are small studies in literature about association between ABO blood groups and chronic viral hepatitis, only few studies found relation between them. The objective of this case control study is to establish a relation between the host factors and these viral infections.Methods: This is a case control study on patients diagnosed with CVHB and CVHC. The study was conducted on 508 patients reported to Nishtar Hospital, Multan and Sheikh Zayd Hospital, Rahim Yar Khan, Pakistan.709 healthy blood donors were selected as a control group from Nishtar Hospital blood bank during December 2016 and December 2017.The results were subjected to SPSS v.20 for analysis using the chi square test. The patients and blood donors were also asked about certain demographic factors like age, sex and blood transfusions.Results: Among CVHB patients,173(100%), the distribution of blood groups was following: Group A, 38 (21.96%), B, 57 (32.94%), AB, 11 (6.35%), O, 67 (38.72%). 158 (91.32%) were Rh positive and 15 (8.67%) Rh negative. In CVHC patients, 335 (100%), the distribution was following: Group A, 69 (20.59%), B, 123 (36.71%), AB, 24 (7.16%), O, 119 (35.52%). 303 (90.44%) were Rh positive while 32 (9.55%) were Rh negative. In healthy blood donors, 167 (23.55%) were group A, 225 (31.73%) group B, 41(5.78%) group AB, 276 (38.92%) group O.632 (89.13%) were Rh positive and 77 (10.86%) Rh negative.Conclusions: There was no significant difference between blood groups(p>0.5) and Rh(p>0.5) with chronic viral hepatitis. However, it was also observed that the infections of HCV increase among (26-45) years old patients while the HBV infections increase with progression of age. Association of chronic viral hepatitis infection with blood group types needs more studies to get more knowledge about this aspect.
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Noor, Hassan A. Alazmi1 Ghazala Rasool Amal Oshaywi Alanazi Abdalla Mohamed Bakr Ali Razan Fahad S. Alotayfi Khawlah Hameed M. Alanazie Fatimah Khalifah A. Alshammari Azzah Abdullah S. Alazmi Hamasat Mansour M. Alsharari Khulud Najeh N. Alazmi Maram Mohammed M. Alanazi Amjad Mufarh S. Alrwuaili Ahlam Essam M. Saba. "ABO & Rh BLOOD GROUP AS A RISK FACTOR OF HYPOTHYROIDISM." INDO AMERICAN JOURNAL OF PHARMACEUTICAL SCIENCES o6, no. 04 (2019): 7862–70. https://doi.org/10.5281/zenodo.2646261.
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<strong><em>Background:</em></strong><em> The clinical significance of the ABO blood group system extends beyond transfusion medicine as several reports have suggested an important involvement in the development of neoplastic and cardiovascular disorders, peptic ulcers, coagulation and infection.</em><strong><em> Objective: </em></strong><em>to show the prevalence of hypothyroidism in various ABO and Rh blood group subjects, and to examine the strength of association between hypothyroidism and ABO, Rh blood groups subjects in Arar City, Northern Saudi Arabia. <strong>Methods:</strong> </em><em>A cross-sectional study, conducted in Arar city, Northern Saudi Arabia.</em><em> During the period from 1 January to 31 May 2018. </em><em>The study included 746 participants. Collected data analyzed using the SPSS program (version 22). P-value of less than 0.05 considered statistically significant. <strong>Results:</strong></em><em> the total prevalence of hypothyroidism was 5.9%. As regards the blood group, blood group O was the most common (44.5%), followed by blood group A (26.7 %) and B (20.8 %), and the least common one was AB (8%). Rhesus factor (Rh) was positive in 86.1% and negative in 13.9%.</em><em> The majority (</em><em>86.4%) of hypothyroid patients were females (P value=0.0001). The data show a significant difference in hypothyroidism in the different blood groups (P value= 0.048) with group A subjects of the highest association (8% of group A subjects). Rh blood type had no statistically significant association with hypothyroidism. <strong>Conclusion:</strong> The results of our study showed a significant difference in hypothyroidism in the different blood groups with group A subjects of the highest association. Our findings support the need for further investigation to look for the association between </em><em>ABO blood groups </em><em>and hypothyroidism</em><em>, </em><em>further investigations in a larger population are warranted. </em>
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Majeed, Pshtewan D., Karim J. Saleh, and Hussein M. Abdullah. "Detection of Helicobacterpylori Antigens among Patients with Gastroenteritis in Erbil City, Iraq." Polytechnic Journal 9, no. 2 (2019): 138–43. http://dx.doi.org/10.25156/ptj.v9n2y2019.pp138-143.
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Helicobacter pylori is a significant pathogen of the gastrointestinal tract infection connected with gastritis, peptic ulcers, and gastric carcinoma. Its infection influence more than half of the world’s inhabitants. This study aims to reveal the prevalence rate of H. pylori infection among patients with gastroenteritis and to investigate the risk factors such as age, gender, residency, blood group and rhesus factors related to this infection in Erbil city. Of 300 stool specimens from patients presenting with gastroenteritis who were admitted to Rizgary Teaching Hospital, Erbil, Iraq, from September 2018 to February 2019 were collected and screened for the presence of H. pylori antigens using rapid immunochromatographic assay (Camp Medica Group, Bucharest, Romania). A questionnaire sheet was prepared and used for each study subject. Of 300 samples examined, H. pylori were detected in 79 samples (26.33%). The highest rate of H. pylori infection was founded among the age group 21–30 years, but there were no significant differences between them (P > 0.05). A significant relationship between H. pylori infection and gender (male 19.05% and female 33.33%) was recorded (P < 0.05). There was a significant association between H. pylori infection and ABO blood group among patients (P < 0.05), but there is no significant association between H. pylori infection and the type of rhesus factor (P > 0.05) that H. pylori infection was higher in rhesus factor negative compared to rhesus factor positive. The prevalence was significantly higher among rural area (55.56%) than urban area (23.44%) (P < 0.05). We concluded that the spread of H. pylori positive rate was high among patients with gastroenteritis in Erbil city. The great prevalence of H. pylori was founded in the patients with O blood group, urban area, and females. There was no significant association between H. pylori infection and age groups and rhesus factor.
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Gata, Abbas Mehsen, Sumayah Faruq Kasim, Sarah Mohssen Mohammed, and Jaleel Samanje. "Relationship of Blood Groups to the Incidence of Hyperuricemia and Hyperglycemia." Journal of Techniques 3, no. 4 (2021): 32–36. http://dx.doi.org/10.51173/jt.v3i4.383.
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Several experiments have been carried out to estimate the relationship between blood grouping types and the occurrence of diabetes, but not hyperuricemia. The effects of the potential correlation between the ABO blood groups and the incidence of these cases have been recorded in this study. The aim of this study is to see whether there is a connection between ABO blood groups and the occurrence of hyperuricemia and hyperglycemia among samples of Iraqi patients. This research was carried out in Educational Laboratories/Medical City (Baghdad Governorate). The research was carried out of the ABO blood with age range (40-70) years, ABO blood group was performed by the sliding method, while uric acid and glucose blood levels were measured by utilizing an enzymatic procedure. There are significant differences in the levels of uric acid between blood groups (A and AB) and blood groups (A and O), while the levels of serum glucose were highly significant between blood groups (B and AB) and blood groups (AB and O). It is concluded that blood groups type AB could be the most vulnerable to the occurrence of hyperuricemia and hyperglycemia. However, further investigations with consideration to Rhesus factor Rh are required.
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İslamoğlu, Zeynep Gizem Kaya, and Mehmet Unal. "Is there an association of ABO blood groups and Rhesus factor with alopecia areata?" Journal of Cosmetic Dermatology 17, no. 6 (2018): 1271–74. http://dx.doi.org/10.1111/jocd.12491.
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Falah Mahdi Thahad, Rasmiya Hadi Basal, and Athar Hassan Abdullah. "Association of ABO and RH Blood Groups with Diabetes." International Journal of Research in Pharmaceutical Sciences 12, no. 4 (2021): 2342–44. http://dx.doi.org/10.26452/ijrps.v12i4.4866.
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Diabetes mellitus (DM) expresses a so-called metabolic abnormality resulting from a defect in the secretion of insulin secreted by the pancreas, and this causes a metabolic disorder, i.e. the metabolic syndrome of both triglycerides and carbohydrates, which in turn leads to high blood sugar as well. DM consists of two types, one insulin-dependent and the other non-insulin-dependent. In the past years, researchers have found a relationship between each of the ABO blood groups with susceptibility to certain diseases, as it was found that peptic ulcer disease is most affected by people with blood type O. The vast majority of them suffer from stomach cancer in addition to increased susceptibility to sweating. In our current research, our study includes DM metabolic disorder and its relationship to each of the different blood groups of people as well as the ABO/Rhesus (Rh.) factor.
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Jovanovic-Cupic, Snezana, Gorana Stamenkovic, Jelena Blagojevic, N. Vanis, B. Stanojevic, and Lj Berberovic. "ABO histo-blood groups and Rh systems in relation to malignant tumors of the digestive tract in Bosnia and Herzegovina." Archives of Biological Sciences 60, no. 4 (2008): 593–99. http://dx.doi.org/10.2298/abs0804593j.
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The distribution of ABO blood groups and the Rhesus factor was analyzed in 279 patients who suffered from malignant tumors of the digestive system. Patients were registered retrospectively in the Gastroenterohepatology Clinic, Clinical Center, University of Sarajevo over a discontinuous period of 88 months. From the results obtained, it was concluded that: (a) men became ill from gastric cancer significantly more frequently than women; (b) the frequency of liver carcinoma was three times higher than the global frequency and the frequency neighboring ethnic groups; and (c) patients with blood group B and patients with RhD(-) exhibited a significantly higher proportion of disease.
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Abdelmonem, M., K. Altayyari, H. Wasim, and M. Saleh Abdelfattah. "Prevalence and Distribution of ABO and Rh (D) Factor among Blood Donors in the United Arab of Emirates." American Journal of Clinical Pathology 160, Supplement_1 (2023): S107. http://dx.doi.org/10.1093/ajcp/aqad150.235.
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Abstract Introduction/Objective Karl Landsteiner discovered the ABO blood group system in 1900, which was the first human blood group system. The Rh blood group system was found forty years later. The antigens on the surface of red blood cells are used to classify people into ABO blood groups. In the ABO system, there are four types: A, B, AB, and O; in the rhesus system, there are two types: Rh-positive and Rh-negative. Blood group identification is critical for efficiently managing blood banks and blood transfusion services to avoid serious transfusion reactions. Methods/Case Report The study was performed on a total of 5996 healthy blood donors in the United Arab of Emirates (UAE). ABO and Rh (D) groupings were performed on all donors' samples by the gel electrophoresis technique. Data on the frequency of ABO and Rh(D) blood groups were reported in numbers and percentages. Results (if a Case Study enter NA) The study revealed that type O is the most prevalent blood group in the United Arab Emirates (43.83%), followed by A at 26.68% and B at 23.90%, with AB having the lowest prevalence at 5.58%; O &gt; A &gt; B &gt; AB. Our study found that 92.57% of the donor population was Rh-positive, whereas 7.43% was Rh- negative. The IA, IB, and IO allele frequencies were determined using the Hardy-Weinberg rule of equilibrium. The gene frequencies are calculated to be 0.1942 for IA (p), 0.1438 for IB (q), and 0.6620 for IO (r). O (r) has the most value in UAE, followed by A (p) and B (q); O &gt; A &gt; B. OO constituted 43.83% of the homozygous types, AA 3.77%, and BB 2.06%. The heterozygous types were 25.71% for AO, 19.03% for BO, and 5.58% for AB. Conclusion The study gives reliable ABO gene frequency statistics and information on the distribution of ABO blood group Rh groups of various alleles in the United Arab Emirates. This knowledge aids in the efficient management of the blood bank's inventory. It will aid transfusion services in anticipating future health issues and improving blood transfusion practice. The study is the first to give reliable ABO gene frequency statistics and information on the distribution of ABO blood group Rh groups of various alleles in the United Arab Emirates. This knowledge aids in the efficient management of the blood bank's inventory. It will aid transfusion services in anticipating future health issues and improving blood transfusion practice.
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Romshoo, Gh Jeelani, Md Youssuf Bhat, G. M. Malik, et al. "Helicobacter pylori Infection in Various ABO Blood Groups of Kashmiri Population." Diagnostic and Therapeutic Endoscopy 4, no. 2 (1997): 65–67. http://dx.doi.org/10.1155/dte.4.65.
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Aim: This study was carried out to assess the prevalence of Helicobacter pylori infection in various ABO blood groups of people of Kashmir.Method: The study comprised 80 individuals – 50 peptic ulcer patients (whose disease was diagnosed by endoscopy) and 30 asymptomatic volunteers. Every subject's blood group and Rhesus status was determined by standard serological tests. Helicobacter pylori infection was diagnosed by three different methods viz., one minute endoscopy room test (urease test), Gram staining and by histology. The detection of Helicobacter pylori by histological examination using Giemsa staining was taken as the ‘gold standard’ for the presence of Helicobacter pylori infection.Results: Out of 80 individuals, 67 were males and 13 females aged between 18–65 years. The majority of peptic ulcer patients had blood group ‘O’ (n = 28.56%). The prevalence of Helicobacter pylori infection amongst peptic ulcer patients was 76%. There was no difference in Helicobacter pylori positivity in various blood groups.Conclusion: Blood group ‘O’ though a risk factor for peptic ulcer (Duodenal ulcer) is not a risk factor for acquiring Helicobacter pylori infection.
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Gautam, Anju, Neelam Mittal, TB Singh, Ruchi Srivastava, and PushpendraKumar Verma. "Correlation of ABO blood group phenotype and rhesus factor with periodontal disease: An observational study." Contemporary Clinical Dentistry 8, no. 2 (2017): 253. http://dx.doi.org/10.4103/ccd.ccd_307_17.
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Iro, Aminata, Moustapha Mahamane Lamine, Ramatoulaye Hamidou Lazoumar, et al. "Transfusional Malaria and Associated Factors at the National Blood Transfusion Center of Niamey-Niger." Journal of Tropical Medicine 2019 (April 1, 2019): 1–5. http://dx.doi.org/10.1155/2019/7290852.
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Summary.Problem. Transfusional malaria is an accidental transmission ofPlasmodiumvia a blood transfusion. Its magnitude is underestimated and very little data on the assessment of this risk are available in Niger.Objective. This study aimed to determine the prevalence of plasmodial infection of blood bags at the National Blood Transfusion Center of Niamey (NBTC).Methodology. A cross-sectional study to diagnosePlasmodiuminfection by microscopy and Rapid Diagnostic Test (RDT) was carried out during the rainy season (September to November 2015). Blood grouping was performed by the BETH-VINCENT technique.Results. One thousand three hundred and fifty-seven (1357) blood bags were collected. One hundred and fifty-seven (11.6%) of the donors were infected withPlasmodiumby microscopy and 2.4% (9/369) by rapid diagnostic test. All infections were withP. falciparum(100%). The mean parasite density was 197 parasites/μL (SD=281; [80: 2000]). There were no significant differences in infection prevalence between the ABO blood groups (p=0.3) or the rhesus positivity (p=08). There is also no significant difference in temporal (p=0.1) and spatial (p=0.6) distribution.Conclusion. The transmission of transfusional malaria during the rainy season is a fact in Niger. Such risks were independent of the ABO blood type and positivity for the rhesus antigen. Pretransfusion diagnosis or posttransfusion therapy should be instituted to prevent it.
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Jain, Aditi, Devaraj G., Harinder Kuckreja, and KBS Kuckreja. "Blood Groups: A Probable Link to Periodontal Diseases." Dental Journal of Advance Studies 05, no. 01 (2017): 047–50. http://dx.doi.org/10.1055/s-0038-1672080.
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AbstractThe presence or absence of blood group antigens has been associated with various diseases, with antigens also acting as receptors for infectious agents. There is paucity of literature available in assessing the relative liability of blood group phenotypes to periodontal diseases. The objective of this study was to determine the association of the ABO blood group and Rhesus factor with periodontal disease to assess whether they can behave as predictors of periodontal diseases. The data was collected from randomly selected 100 individuals who were referred to the Department of Periodontics & Implantology, Mahatma Gandhi Dental College & Hospital, Jaipur for periodontal ailment management or for other reasons related to dental health. The subjects were categorized into three groups according to Russel's Periodontal index: healthy periodontium, gingivitis & periodontitis. Blood samples were collected to identify the ABO blood group and Rh factor by the slide method. The effect of blood subgroups on periodontal health, gingivitis and periodontitis was investigated separately. Results & Conclusion: More number of healthy subjects in blood group A. Gingivitis and periodontitis were found more in blood group O and blood group AB, respectively. Rh positive subjects had higher distribution in all study groups.
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Dharma, Samjotha, Sahana Purushotham, and Sreeraj Surendran. "Variation of ABO phenotypes, Rhesus factor and salivary secretor status in chronic periodontitis patients with and without type II diabetes mellitus: A cross sectional study." Biomedicine 44, no. 1 (2024): 125–30. http://dx.doi.org/10.51248/.v44i1.3893.
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Introduction and Aim: While numerous studies have explored the connection between ABO blood groups and disease incidence in various medical contexts, there has been a scarcity of research dedicated to examining the relationship between ABO blood groups and the occurrence of oral diseases with a specific focus on those with and without Type II diabetes mellitus. Understanding the patient’s blood group and salivary secretor status might help to create a new qualitative personalized approach in preclinical diagnosis and to develop preventive measures. Hence, this study delves into the correlation between ABO phenotypes, Rhesus factor, and salivary secretor status in chronic periodontitis patients, with and without Type 2 Diabetes Mellitus Materials and Methods: The study sample comprised 120 subjects aged between 35 and 60 years. Participants were categorized into three groups: Group A, consisting of patients with only chronic periodontitis; Group B, including patients with only Type II Diabetes Mellitus; and Group C, comprising individuals with both chronic periodontitis and Type II Diabetes Mellitus. Salivary secretor status was determined using the absorption elution method. Results: Group B showed the highest percentage of salivary secretors (97.5%), followed by group A (95%) and group C showed the least percentage of secretors (92.5%). Group B showed the least percentage of non-secretors (2.5%), Group A showed 5% and group C showed the highest percentage of non-secretors (7.5%). The common blood groups in Study Group A were O>B>A>AB. Similarly in Group B, the blood groups were B>O=A>AB and finally in Study Group C, the common blood groups were B>A>O>AB. Majority of the individuals were Rh Positive. Conclusion: The current study has identified a correlation between ABO phenotype, Rh phenotype, and secretor status among individuals with periodontitis, both with and without type 2 diabetes.
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Ezugwu, Absalom E., Olumuyiwa Otegbeye, Prinolan Govender, and John O. Odo. "Computational Intelligence Approach to Dynamic Blood Allocation With ABO-Rhesus Factor Compatibility Under Real-World Scenario." IEEE Access 8 (2020): 97576–603. http://dx.doi.org/10.1109/access.2020.2997299.
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Balaouras, George, Paolo Eusebi, and Polychronis Kostoulas. "Systematic review and meta-analysis of the effect of ABO blood group on the risk of SARS-CoV-2 infection." PLOS ONE 17, no. 7 (2022): e0271451. http://dx.doi.org/10.1371/journal.pone.0271451.
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We have been experiencing a global pandemic with baleful consequences for mankind, since the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was first identified in Wuhan of China, in December 2019. So far, several potential risk factors for SARS-CoV-2 infection have been identified. Among them, the role of ABO blood group polymorphisms has been studied with results that are still unclear. The aim of this study was to collect and meta-analyze available studies on the relationship between SARS-CoV-2 infection and different blood groups, as well as Rhesus state. We performed a systematic search on PubMed/MEDLINE and Scopus databases for published articles and preprints. Twenty-two studies, after the removal of duplicates, met the inclusion criteria for meta-analysis with ten of them also including information on Rhesus factor. The odds ratios (OR) and 95% confidence intervals (CI) were calculated for the extracted data. Random-effects models were used to obtain the overall pooled ORs. Publication bias and sensitivity analysis were also performed. Our results indicate that blood groups A, B and AB have a higher risk for COVID-19 infection compared to blood group O, which appears to have a protective effect: (i) A group vs O (OR = 1.29, 95% Confidence Interval: 1.15 to 1.44), (ii) B vs O (OR = 1.15, 95% CI 1.06 to 1.25), and (iii) AB vs. O (OR = 1.32, 95% CI 1.10 to 1.57). An association between Rhesus state and COVID-19 infection could not be established (Rh+ vs Rh- OR = 0.97, 95% CI 0.83 to 1.13).
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Getawa, Solomon, Biruk Bayleyegn, Melak Aynalem, Yilkal Belete Worku, and Tiruneh Adane. "Relationships of ABO and Rhesus blood groups with type 2 diabetes mellitus: a systematic review and meta-analysis." Journal of International Medical Research 50, no. 10 (2022): 030006052211295. http://dx.doi.org/10.1177/03000605221129547.
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Objectives The susceptibility to type 2 diabetes mellitus (T2DM) has been linked to blood type. We aimed to characterize the relationships of the ABO and Rhesus blood groups with T2DM. Methods Literature searches were performed using the Medline, PubMed, Scopus, Cochrane, EMBASE, and Google Scholar databases to identify studies published up to 31 March 2022. The PRISMA guidelines were used for reporting. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were obtained using fixed-effects models. Results Twenty-six studies of 6870 patients with T2DM and 11,879 controls were identified. Compared with the other ABO groups, people with blood type B were at higher risk of T2DM (OR: 1.30, 95% CI: 1.20–1.41), while group O was associated with a lower risk (OR: 0.92, 95% CI: 0.86–0.98). There were no significant associations of T2DM with blood types A or AB, or Rh factor. Conclusion Individuals with blood type B are at higher risk of developing T2DM. Therefore, they should be screened for T2DM on a frequent basis and be made aware of the importance of maintaining a balanced diet and regular exercise for the prevention of obesity and T2DM. PROSPERO registration number CRD42022353945.
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Kumar, Sachin, Mayurika Subodh Kumar Tyagi, Swati Singh, and Priyanka Chaurasiya. "Epidemiology of ABO and rhesus blood groups in blood donors at a North Indian tertiary care hospital." Santosh University Journal of Health Sciences 10, no. 2 (2024): 184–87. https://doi.org/10.4103/sujhs.sujhs_64_24.
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ABSTRACT Background: The ABO blood type system has been the most crucial in transfusion medicine since it is discovered by Karl Landsteiner. Studies of population migration patterns and the resolution of certain medicolegal problems, especially those involving disputed paternity, highlight the significance of the blood group systems in population genetics. The purpose of this research was to collect information on the ABO and rhesus (Rh) blood type frequencies and distributions among donors in a tertiary care hospital in North India. Materials and Methods: Data were collected retrospectively from January 2018 to June 2023 of donors and analyzed sequentially for their ABO and Rh blood groups. Donor blood groups were determined using test tube and column agglutination techniques, with forward and reverse methods, with the aid of widely available standard monoclonal antisera. Results: The findings showed that blood group B (38%) was the most frequent among donors, followed by O (28%) and A (23%). The blood group with the lowest frequency was AB (11%). The majority of donors were Rh-positive (93.9%). About 6.1% of the population were negative for the Rh factor. Conclusion: It was observed that the most prevalent blood group throughout the entire duration of the study, among both males and females, was B, accounting for 37.80% of the population. The prevalence of RhD-negative in the population was shown to be only 6.10%. Based on the findings of the current investigation and previous relevant studies, it can be deduced that the B blood group exhibits the highest prevalence rates within the examined region, followed by blood groups O (30.73%), A (23.20%), and AB (10.90%). This project will provide valuable insights for the effective management of blood bank and transfusion services, as well as the maintenance of comprehensive donor records for future utilization.
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Boycheva, Maria, Biljana Boycheva, and Velislav Todorov. "CARCINOMA GLANDULAE PAROTIS AND BLOOD GROUP AFFILIATION." Journal Scientific and Applied Research 22, no. 1 (2022): 5–9. http://dx.doi.org/10.46687/jsar.v22i1.331.
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The current study included 83 patients with Ca glandulae parotis (72 men and 11 women) whose blood group affiliation to the AB0 and Rhesus factor systems was monitored. A comparison was made with a control group of healthy individuals from the modern Bulgarian population. The distribution of the blood groups in the sample was different from that of the control group (p <0.001). There was a significant increase in the prevalence of persons with blood group B (p <0.001), and a significant decrease in groups 0 (p <0.001) and A (p <0.05). In group AB, a slight increase in frequency was detected. With respect to the Rhesus factor, there was an increase in the patients with positive Rhesus factor - by 9.23% to 93.94% (p<0.05). It can be assumed that, among other risk factors, belonging to group B and having a positive Rhesus factor are one of the reasons for the appearance and development of the disease.
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Ilango, Paavai, Sanjay M. Cherian, Arulpari Mahalingam, Vineela Katam Reddy, Ayswarya V. Vummidi, and G. D. Gomathi. "COVID-19 Susceptibility among ABO/RH Blood Groups in Tamil Nadu Population: A Retrospective Case–Control Study." Journal of Indian Association of Public Health Dentistry 22, no. 2 (2024): 174–78. http://dx.doi.org/10.4103/jiaphd.jiaphd_213_21.
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Background: COVID-19 is a world pandemic with clinical manifestation from mild subclinical infection to severe illness. Literature suggests an evident correlation between the ABO blood group, Rhesus blood group, and COVID-19 in the recent past. The role of blood group in disease susceptibility and severity of COVID-19 varies in different geographical locations, as ABO blood group distribution varies among the human population with the impact of migration. Although various research have been done globally, scientific evidence with respect to the south Indian population remains limited, emphasizing the need for the present study to analyze the association of COVID-19 and blood groups in Tamil Nadu. Aim: The aim of this study was to analyze the potential susceptibility of COVID-19 among the blood groups (ABO and Rh type) in Tamil Nadu population. Materials and Methods: This was a noninterventional retrospective case–control study, with 500 patients who tested positive for COVID-19 being taken as the “cases,” while another 500 who tested negative were taken as the “controls.” The medical records, including the blood group and Rh factor, were collected from the government-recognized testing centers (Government Medical Hospital and Primary Health Centers, Tiruvallur, and Frontier Lifeline Hospital, Chennai) in Tamil Nadu, who came for COVID-19 screening by reverse transcriptase–polymerase chain reaction. The data were analyzed to associate its correlation with different blood groups. Results: Blood Group A showed significantly higher distribution among the cases (P = 0.030), and blood Groups O and B were significant among the controls (P = 0.026 and P = 0.000, respectively). Blood Group AB did not show any significant differences between the groups (P = 0.374). The odds ratio for AB, A, O, and B Groups for Rh (positive and negative) were shown to be 0.659, 0.591, 0.472, and 0.262, respectively, suggesting increased susceptibility toward Rh positive factor. Conclusion: In our study, blood Group A was found to be the most susceptible and blood Group O to be the least susceptible to COVID-19 in the Tamil Nadu population. In addition, the Rh positive factor showed more inclination toward COVID susceptibility than the Rh negative factor. ABO blood group may be considered a potential nonmodifiable and secondary risk factor for COVID-19 contributing to the disease pathobiology at immunological, biochemical, and physiological levels. Still, the intensity of their role and their exact mechanism in its association requires further exploration to validate the current findings.
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Warsame, Hawa Ali, Cyrus Theuri, Naima Mukhtar Abdullahi, Abdulkadir Mohamed Ahmed Keynan, and Mohamed A. M. Ahmed. "Prevalence and risk factors for neonatal jaundice: a multicentre analytical cross-sectional study at neonatal intensive care units, Mogadishu, Somalia." BMJ Open 15, no. 3 (2025): e096692. https://doi.org/10.1136/bmjopen-2024-096692.
Full textAbstract:
ObjectivesTo determine the prevalence and risk factors for neonatal jaundice among neonates admitted in three large hospitals in Mogadishu, Somalia.DesignHospital-based analytical cross-sectional study.SettingNeonatal intensive care units (NICUs) of three tertiary hospitals in Mogadishu, Somalia.Participants423 neonates admitted in NICUs and their mothers.ResultsThe overall prevalence of neonatal jaundice was 30.26%. Results of multiple logistic regression indicated that the risk of neonatal jaundice was highest for neonates of mothers aged more than 35 years (adjusted OR (AOR): 6.03, 95% CI: 2.46 to 15.13), mothers who had prolonged labour (AOR: 3.29, 95% CI: 1.79 to 6.08) and those delivered vaginally (AOR: 2.75, 95% CI: 1.56 to 4.97) compared with caesarean section. The risk of neonatal jaundice was lower for male neonates (AOR: 0.47, 95% CI: 0.28 to 0.76) and higher for neonates who had ABO incompatibility (AOR: 22.26, 95% CI: 3.54 to 249.62), rhesus (Rh) incompatibility (AOR: 14.10, 95% CI: 1.11 to 2021.73) and neonatal sepsis (AOR: 1.96, 95% CI: 1.15 to 3.39).ConclusionsHigher maternal age, prolonged labour, blood group ABO incompatibility, Rh incompatibility and neonatal sepsis are significant risk factors for neonatal jaundice. Efforts for prevention and timely management of ABO and Rh incompatibility, prolonged labour and neonatal sepsis are required to reduce cases of neonatal jaundice. Special attention should be given to newborns of older mothers and those born through vaginal delivery as they are at higher risk of developing neonatal jaundice. Further research is needed to conclusively identify the role of neonatal sex as a risk factor for neonatal jaundice.
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Anfal akram Hasan, Mohammed Ahmed Jassim Alogaidi, and Areej Ali Abbood. "Factors affecting the severity of RH Incompatibility newborn." Indian Journal of Forensic Medicine & Toxicology 15, no. 4 (2021): 595–601. http://dx.doi.org/10.37506/ijfmt.v15i4.17168.
Full textAbstract:
Rh incompatibility is a not common pediatric problem, that cause morbidity and mortality in children, and it is an important cause of hemolysis, anemia and jaundice in newborn. To study Rhesus hemolytic disease, its severity, its complications; to evaluate if ABO incompatibility is protective or not, so to find out the efficacy of anti-D globulin ; to evaluate the efficacy of phototherapy and exchange transfusion as a treatment.
 This study was done on neonates with jaundice, seventy five patients (1-10 days old) who had Rh incompatibility were studied during period from the first of January 2008 to the 30th of June 2008.
 History was taken about age, gender and gestational age of the patients, determination of gestational age and hepatosplenomegally as a cause of extramedullary hematopoiesis. Investigations done for patients were hemoglobin, total serum bilirubin, reticulocyte count, blood group and Rh, and direct coombs test. From 75 patients studied, 55 patients (73%) required treatment for jaundice;25 of them (46%) required only phototherapy due to mild degree of hemolysis, and 30 of them (54%) required exchange transfusion with phototherapy due to severe degree of hemolytic. The remaining 20 patients (27%) required observation alone.
 Family history of previous hemolysis was positive in 44 patients and it was a risk factor for having hemolysis in present pregnancy. Early evaluation of patients for jaundice was useful in early recovery. ABO incompatibility in association with Rh incompatibility was not necessarily protective against hemolysis. The administration of anti-D globulin to the mother within first 72 hours after delivery was protective against sensitization.
 Early and proper management of of Rh incompatibility may reduce need for exchange transfusion. ABO incompatibility was not necessarily protective against hemolysis. Anti-D globulin administered to mothers within 3 days after delivery was protective against sensitization, History of hemolytic in previous siblings is considered as a risk factor for present hemolytic in neonates with Rh incompatibility.
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Nurudini, Nurath Kanule, Almachius Kahwa, and Bakari M. M. Mwinyiwiwa. "Development and Experimental Validation of a Non Invasive Blood Group Detection System." Tanzania Journal of Engineering and Technology 44, no. 2 (2025): 68–79. https://doi.org/10.52339/tjet.v44i1.1267.
Full textAbstract:
An individual's blood group consists of red blood cell antigens whose composition is determined by protein presence, antigen structure, and gene series. Persons aged above six months have significant anti-A and/or anti-B in their serum. During transplantation and transfusion, ABO blood group identification is the most essential factor. The conventional method involves drawing blood samples from patients, and the blood group is determined based on the antigen-antibody reaction. This method consists of adding chemical reagents. However, this requires time of operation, and throughput analysis is high, and the process is also challenging to interpret. Accurate and rapid identification of blood groups is therefore crucial in various medical fields, including blood transfusions, organ transplants, and prenatal care. Traditional methods for blood typing often require extensive laboratory equipment and trained personnel, leading to delays and potential errors in critical situations. This research focuses on developing a non-invasive, compact, and user-friendly device capable of determining blood groups quickly without invasively collecting patient’s blood samples and using reagents. The system learns from a database of annotated blood samples by employing machine learning algorithms, enhancing its accuracy and reliability over time. A non invasive blood group detection system was verified experimentally on a laboratory prototype, achieving an accuracy of 95.9% in identifying blood groups and rhesus factors. Furthermore, a comparative analysis was conducted between the proposed system and existing counterparts. This analysis demonstrated that the proposed system outperforms others in accuracy, indicating the rhesus factor.