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Dissertations / Theses on the topic 'ABO antigens'

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Published: 4 June 2021
Last updated: 11 February 2022

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1

Bianco-Miotto, Tina. "Loss of ABO antigens in haematological malignancies." Adelaide, S.A, 2002. http://web4.library.adelaide.edu.au/theses/09PH/09phb578.pdf.

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"May 2002" Includes bibliographical references (leaves 229-251) Describes the investigation of the alteration of ABH antigen expression on the surface of red blood cells in patients with haematological malignancies.
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2

Kandeva, Teodora N. 1983. "Humoral response to carbohydrate antigens in the context of ABO-incompatible transplantation and xenotransplantation." Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=116121.

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Antibody-mediated rejection is central to ABO incompatible transplantation as well as to xenotransplantation. The xenoantigen alpha-Gal has a highly analogous carbohydrate structure to the human blood group antigens, and both require memory B cell activation for antibody production. We hypothesize that B cells, reactive to the alpha-Gal xenoantigen and B blood group antigen, require the presence of fully activated T cells in order to survive and proliferate in vitro, contrary to the traditional theory that humoral response to carbohydrate antigens is a T cell-independent process. When we compa
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3

Patenaude, Sonia I. "Structural studies of the biosynthesis and recognition of the human ABO(H) blood group antigens." Thesis, University of Ottawa (Canada), 2002. http://hdl.handle.net/10393/6188.

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High-resolution crystal structures of the human ABO blood group glycosyltransferase enzymes, unliganded and in complex with substrate molecules, reveal the basis for their substrate specificity and suggest amino acid residues important in catalysis. The human ABO(H) blood group glycosyltransferases differ in only 4 amino acid residues and are therefore two of the most homologous, naturally occurring glycosyltransferases known that utilize different naturally occurring donor molecules. An N-acetylgalactosaminyltransferase (GTA) uses a UDP-GalNAc donor to convert the H-antigen to the A-antigen,
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4

Tanaka, Yuichi. "Intragraft expression of recipient-type ABO blood group antigens : long-term follow-up and histological features after liver transplantation." Kyoto University, 2006. http://hdl.handle.net/2433/143871.

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5

Pozzobon, Rochele Camila Rohde. "EXPRESSÃO DE ANTÍGENOS DO SISTEMA SANGUÍNEO ABO ASSOCIADOS À PREDISPOSIÇÃO E AO PROGNÓSTICO DE CÂNCER DE MAMA." Universidade Federal de Santa Maria, 2010. http://repositorio.ufsm.br/handle/1/5933.

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In Brazil, breast cancer (BC) is the most common malignant neoplasic diseases among women. The identification of markers that can predict the behavior of tumors is especially important, mainly due to variability in clinical disease progression. It has been a high number of new prognostic factors mentioned in literature in recent years. The inclusion of new predictors provides advances that lead to an even better selection of patients for adjuvant therapy primarily, being able to reach a better individualization of therapeutics. Many studies have shown an association between certain blood
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6

Camargo, Ulisses. "Sistemas Histo-sanguíneos ABO, Secretor e Lewis como fatores de risco para a espondilite anquilosante." Faculdade de Medicina de São José do Rio Preto, 2016. http://hdl.handle.net/tede/396.

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Submitted by Fabíola Silva (fabiola.silva@famerp.br) on 2018-02-07T18:29:25Z No. of bitstreams: 1 ulissescamargo_tese.pdf: 700757 bytes, checksum: 68231dab9197a8717320c0e887f2b2f6 (MD5)<br>Made available in DSpace on 2018-02-07T18:29:25Z (GMT). No. of bitstreams: 1 ulissescamargo_tese.pdf: 700757 bytes, checksum: 68231dab9197a8717320c0e887f2b2f6 (MD5) Previous issue date: 2016-09-22<br>Introduction. The spondyloarthritis encomprises a group of diseases strongly associated with HLA-B*27 gene. It has been proposed that genes not belonging to the major histocompatibility complex human influe
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7

Geraldo, Alexandre. "Efeito do consumo de probioticos sobre o título de anticorpos do sistema ABO." reponame:Repositório Institucional da UFSC, 2013. https://repositorio.ufsc.br/handle/123456789/107397.

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Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2013<br>Made available in DSpace on 2013-12-06T00:00:48Z (GMT). No. of bitstreams: 1 318438.pdf: 1197690 bytes, checksum: d7b7c394fe8be0ae876dd221c456e73a (MD5) Previous issue date: 2013<br>O intestino possui uma grande diversidade microbiana e parte desta é responsável por estimular os anticorpos os do Sistema ABO. Pacientes que possuem anticorpos anti-ABO no plasma podem apresentar uma diminuição da concentração plaquetária após a transfusão de
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8

BARTHELEMY, ASTIC PASCALE. "Les allo-immunisations foeto-maternelles par antigenes erythrocytaires autres que abo et rhesus d : a propos de 114 cas." Lyon 1, 1993. http://www.theses.fr/1993LYO1M251.

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9

Mollicone, Rosella. "Les antigenes de groupes sanguins abh, lewis et apparentes : distribution tissulaire normale et controle genetique." Paris 6, 1987. http://www.theses.fr/1987PA066133.

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10

Abou-Chaker, Khalil [Verfasser]. "Entwicklung eines Partikel-Gel-Agglutinationstests zum Nachweis von Einzelnukleotidpolymorphismen und zur Phänotypisierung granulozytärer Antigene / Khalil Abou-Chaker." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2011. http://d-nb.info/1029847169/34.

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11

Mollicone, Rosella. "Les Antigènes de groupes sanguins ABH, Lewis et apparentés distribution tissulaire normale et contrôle génétique /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376081388.

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12

Guillon, Patrice. "Antigènes tissulaires de groupe sanguin ABH acteurs de la protection innée antivirale : exemples des Calicivirus (NV et RHDV) et du Coronavirus SRAS-CoV." Nantes, 2008. https://archive.bu.univ-nantes.fr/pollux/show/show?id=d7627fae-7b41-4797-ad78-963bffc5f6c7.

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Les antigènes tissulaires de groupe sanguin sont des motifs glycanniques présents sur les cellules épithéliales ou dans les sécrétions et également trouvés sur les érythrocytes de certains primates. Leur synthèse nécessite l’action de glycosyltransférases codées par les gènes Fut1, Fut2, Sec1 ou Abo. Ils servent de ligands à diverses souches de Calicivirus du genre norovirus responsables de gastro-entérites chez l’homme, le polymorphisme aux loci FUT2 et ABO contrôlant la sensibilité à ces virus. Dans ce travail nous montrons que le lait maternel contient des molécules de type mucine qui inhib
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13

Marionneau-Lambot, Séverine. "Étude du rôle des antigènes ABH et Lewis dans deux pathologies : le cancer colique et les gastro-entérites à Novovirus." Nantes, 2002. http://www.theses.fr/2002NANT26VS.

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Alors que la structure et la biosynthèse des antigènes glucidiques de groupes sanguins sont bien élucidées, leurs fonctions biologiques restent mal connues. Au cours de cette thèse, nous nous sommes attachés à mieux définir le rôle de ces antigènes de structures dans deux pathologies humaines : le cancer et les gastro-entérites à Norovirus (virus de type Norwalk). Chez l'homme, l'expression des antigènes ABH et Lewis est modifiée au cours de la cancérogenèse. Afin de mieux comprendre la signification biologique de ces altérations, nous avons utilisé un modèle d'adénocarcinome colique de rat. E
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14

Dubois, Sonia. "Caractérisation de nouveaux régulateurs de l'activation lymphocytaire et de la lymphomagenèse." Thesis, Paris 11, 2015. http://www.theses.fr/2015PA11T033/document.

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Le lymphome diffus à grandes cellules B (DLBCL, Diffuse Large B-Cell Lymphoma) constitue le lymphome non Hodgkinien le plus fréquemment diagnostiqué. Les DLBCL sont composés principalement de deux sous groupes : l’entité nommée ABC (Activated B Cell-like) qui est la plus agressive, avec un taux de survie de 30% après traitement, et l’entité GCB (Germinal-Center B Cell). Contrairement aux GCB DLBCL, les ABC DLBCL se caractérisent par une signature génique similaire aux lymphocytes B activés par leur récepteur antigénique (BCR, B Cell Receptor) à cause de l'accumulation de mutations génétiques.
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15

Ivan, Busarčević. "Značaj testa inhibicije hemaglutinacije pljuvačke i Lewis fenotipa u ispitivanju udruženosti sekretornog statusa i seronegativnih spondiloartropatija." Phd thesis, Univerzitet u Novom Sadu, Medicinski fakultet u Novom Sadu, 2017. http://www.cris.uns.ac.rs/record.jsf?recordId=102337&source=NDLTD&language=en.

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Uvod: Pojam &quot;sekretor&rdquo; ili &bdquo;nesekretor&quot; se odnosi na sposobnost pojedinca da luči antigene krvnih grupa ABO sistema u telesnim tečnostima. Određivanje ABO krvne grupe i sekretornog statusa, testom inhibicije hemaglutinacije pljuvačke i Lewis fenotipa na eritrocitima su važni u kliničkoj i forenzičkoj medicini, u odnosu na etiopatogenezu mnogih bolesti. Nesekretorstvo ABO krvnogrupne supstance je udruženo sa če&scaron;ćom pojavom autoimunih inflamatornih oboljenja među kojima su i seronegativne spondiloartropatije. Veća učestalost seronegativnih spondiloartropatija među os
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16

Ponchel, Guillaume. "Etudes structurales et fonctionnelles de deux alpha-galactosidases actives sur les antigènes B et alpha3 Gal." Thesis, Aix-Marseille, 2012. http://www.theses.fr/2012AIXM4017.

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Les conversions enzymatiques des antigènes du système des groupes sanguins ABO et de l'antigène majeur de xénotransplantation &#945;3Gal représentent des alternatives thérapeutiques afin d'améliorer l'approvisionnement des hôpitaux en sang de groupe O et la transplantation d'organes. La famille GH110 des glycoside hydrolases comprend des enzymes actives sur les antigène B et &#945;3Gal à pH neutre et fonctionnant avec un mécanisme catalytique par inversion. La sous&#8208;famille GH110_A regroupe des membres actifs exclusivement sur l'antigène B, tandis que la sous&#8208;famille GH110_B regroup
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17

Araújo, Renan Bandeirante de [UNESP]. "O modo de vida just-in-time do novo perfil metalúrgico jovem-adulto flexivel do ABC: antigos dilemas, novas contradições e possibilidades." Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/106302.

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Made available in DSpace on 2014-06-11T19:35:37Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-04-23Bitstream added on 2014-06-13T20:26:33Z : No. of bitstreams: 1 araujo_rb_dr_arafcl.pdf: 832837 bytes, checksum: 15502a1bc67426c8287b032a6312cfb0 (MD5)<br>Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)<br>Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)<br>Em nossa pesquisa foi possível constatar que a indústria montadora situada na região do ABC paulista, aqui analisada, a partir de 1992 promoveu intenso processo de mudanças na sua estrutura pro
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18

Araújo, Renan Bandeirante de. "O modo de vida "just-in-time" do novo perfil metalúrgico jovem-adulto flexivel do ABC : antigos dilemas, novas contradições e possibilidades /." Araraquara : [s.n.], 2009. http://hdl.handle.net/11449/106302.

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Orientador: Maria Orlanda Pinassi<br>Banca: Claudia Mazzei Nogueira<br>Banca: Fábio Kazuo Ocada<br>Banca: Sérgio César da Fonseca<br>Banca: Giovanni Antonio Pinto Alves<br>Resumo: Em nossa pesquisa foi possível constatar que a indústria montadora situada na região do ABC paulista, aqui analisada, a partir de 1992 promoveu intenso processo de mudanças na sua estrutura produtiva, resultando na emergência de um segmento operário jovem-adulto flexível de novo perfil histórico-social e profissional. Trata-se de uma nova parcela de "colaboradores" situados entre 15 e 35 anos de idade, cujo modo de v
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19

Van, der Merwe Helanie. "Evaluation and validation of in vitro assays to determine cell viability for HIV/AIDS expermentation with Pheroid TM technology / Helanie van der Merwe." Thesis, North-West University, 2008. http://hdl.handle.net/10394/4171.

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The Southern parts of Africa have the highest prevalence of HIV-infected people and South Africa is the country with the highest number of infections in the world. There is still no cure for AIDS, but anti-HIV medicine can prolong and enhance the quality of life of an HIV infected person. Patient adherence with antiretroviral therapy is extremely low due to difficult dosing intervals, problematic dosage forms, instability of the antiretrovirals (ARVs) and the severe side-effects caused by these drugs; this leads to resistance of HIV to these drugs. Pheroid™ technology is a patented delivery sy
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20

Clément, Marc. "Rôle du CD31 lors des intéractions cellulaires impliquées dans les pathologies inflammatoires chroniques." Paris 7, 2014. http://www.theses.fr/2014PA077010.

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L'équilibre entre les signaux activateurs et inhibiteurs permet l'adaptation du comportement des cellules immunitaires innées et adaptatives à la situation rencontrée. Une perturbation de cet équilibre peut être préjudiciable à l'homéostasie de l'organisme. L'activation de signaux inhibiteurs puissants lorsque les cellules immunitaires doivent être activées peut entraver des mécanismes immunitaires fondamentaux et permettre la prolifération de virus, de bactéries et de cellules cancéreuses. La destruction progressive des tissus et des organes, par ces pathogènes, peut entraîner des manifestati
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21

Durgeau, Aurélie. "La préprocalcitonine : régulation de l'apprêtement de l'épitope tumoral ppCT₁₆-₂₅ par les transporteurs TAP et identification de nouveaux peptides antigéniques." Paris 7, 2012. http://www.theses.fr/2012PA077130.

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Nous avons identifié un antigène (Ag) tumoral codé par le gène CALCA, qui code la calcitonine, qui est surexprimé dans plusieurs carcinomes bronchiques et les carcinomes médullaires de la thyroïde (MTC). Le peptide antigénique (ppCT₁₆-₂₅), reconnu par un clone T cytotoxique, est issu de la région C-terminale du peptide signal de la préprocalcitonine (ppCT). Il est apprêté indépendamment de la voie classique protéasomes-TAP par un nouveau mécanisme qui implique deux protéases différentes, la signal peptidase (SP) et la signal peptide peptidase (SPP). Au cours de ma thèse, je me suis intéressée
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22

O'Keefe, Denise Susan. "Molecular analysis of changes in ABO blood group antigen expression in haematological malignancy / Denise S. O'Keefe." 1995. http://hdl.handle.net/2440/18642.

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Errata inserted on back end paper.<br>Bibliography: leaves 226-254.<br>xviii, 261 leaves : ill. ; 30 cm.<br>Title page, contents and abstract only. The complete thesis in print form is available from the University Library.<br>Describes the development of techniques to genotype and simultaneously assess allele dosage at the ABO locus using PCR and allele-specific restriction enzyme digestion.<br>Thesis (Ph.D.)--University of Adelaide, Dept. of Medicine, 1996
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23

吳奇諺. "The ABC of the Feminine Superego: Antigone, Butler, Copjec." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/86863118985159056260.

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24

Mirakaj, Valbona [Verfasser]. "Analyse des BCR-ABL-Proteins als Antigen zur Induktion von antigenspezifischen zytotoxischen T-Zellen / vorgelegt von Valbona Mirakaj." 2007. http://d-nb.info/983724032/34.

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25

Chen, Grace Yi-Ying. "Functional Analysis of Adapter Protein c-Abl Src Homology 3 Domain-binding Protein 2." Thesis, 2009. http://hdl.handle.net/1807/17740.

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3BP2 is a pleckstrin homology (PH) domain- and Src homology 2 (SH2) domain-containing adapter protein that has been linked through genetic evidence to a rare human disease called cherubism 146. 3BP2 was originally cloned in a screen to identify c-Abl SH3 binding proteins 23,24. In overexpression studies, 3BP2 has been implicated as a positive regulatory adapter molecule coupled to immunoreceptor on T cells 67,69,70, B cells 68, NK cells 71-73 and mast cells 74,75. It was also evident that 3BP2 forms complexes with a number of signaling molecules, such as Zap-70, LAT, phospholipase C-γ1 (PLC
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26

Wendel, Andreas Friedrich [Verfasser]. "Untersuchung der Genexpression von ABC- und SLC-Transmembranproteinen mit Beteiligung am aktiven Transport von Antigenen, Eikosanoiden und Zytostatika beim malignen Melanom / vorgelegt von Andreas Friedrich Wendel." 2009. http://d-nb.info/99962394X/34.

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