Relevant bibliographies by topics / Abortifacient

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  2. Dissertations / Theses
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Academic literature on the topic 'Abortifacient'

Author: Grafiati
Published: 3 June 2025
Last updated: 22 June 2025

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Journal articles on the topic "Abortifacient"

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de Oddone, Nelly Krayacich, Michele G. Shedlin, Michael Welsh, Malcolm Potts, and Paul Feldblum. "Paraguayan pharmacies and the sale of pseudo-abortifacients." Journal of Biosocial Science 23, no. 2 (1991): 201–9. http://dx.doi.org/10.1017/s0021932000019210.

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SummaryThis study was conducted in 1985 in Asunción, Paraguay, 6 years after the closure of the state supported family planning services. Data from national surveys in 1977 and 1987 permit a comparison of sources of contraceptive supplies before and after the elimination of government support for family planning. The purchase of pseudo-abortifacients from private pharmacies was used as an indication of induced abortion. After the loss of government clinics, it is suggested that some women turned to pharmacists to obtain pseudo-abortifacients when faced with unwanted pregnancy. There is an indication of increased pseudo-abortifacient use, particularly among unmarried women and those from poorer neighbourhoods.
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Mbaya, Y.P, D. Yahi, and A. William. "Abortifacient Effects of Aqueous Leaf Extract of Annona senegalensis Pers in Albino Rats." Continental J. Applied Sciences 14, no. 2 (2019): 68–77. https://doi.org/10.5281/zenodo.3524825.

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The use of abortifacient plants is commonly practiced among the natives in Nigeria as an aborting agent of pregnancy. Abortifacient substances are either chemical or physical capable of inducing abortion. One of the plants that is being used is <em>Annona senegalensis</em>, although it is primarily used as food. Its abortifacient activity is not scientifically validated. This study investigated the abortifacient activity of the leaf extract. The aqueous leaf extract of <em>Annona senegalensis</em> pers was screened for abortifacient activity in thirty (30) female albino rats at the doses of 100, 200, 300 and 400 mg/kg daily. The oral administration of the extract to female albino rats for three weeks of the gestation period resulted in reduced individual implantation sites, live fetuses, postimplantation loss and progressive decrease in serum progesterone concentration in a dose dependent manner. <em>Annona senegalensis</em> leaf therefore, has significant abortifacient activity. &nbsp;
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Zordo, Silvia De. "The biomedicalisation of illegal abortion: the double life of misoprostol in Brazil." História, Ciências, Saúde-Manguinhos 23, no. 1 (2016): 19–36. http://dx.doi.org/10.1590/s0104-59702016000100003.

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Abstract This paper examines the double life of misoprostol in Brazil, where it is illegally used by women as an abortifacient and legally used in obstetric hospital wards. Based on my doctoral and post-doctoral anthropological research on contraception and abortion in Salvador, Bahia, this paper initially traces the “conversion” of misoprostol from a drug to treat ulcers to a self-administered abortifacient in Latin America, and its later conversion to aneclectic global obstetric tool. It then shows how, while reducing maternal mortality, its use as an illegal abortifacient has reinforced the double reproductive citizenship regime existing in countries with restrictive abortion laws and poor post-abortion care services, where poor women using it illegally are stigmatised, discriminated against and exposed to potentially severe health risks.
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Austriaco, Nicanor Pier Giorgio. "Is Plan B an Abortifacient?" National Catholic Bioethics Quarterly 7, no. 4 (2007): 703–7. http://dx.doi.org/10.5840/ncbq2007746.

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Wright, Steve. "Abortifacient drugs: ethico-legal issues." Nursing Standard 5, no. 24 (1991): 36–37. http://dx.doi.org/10.7748/ns.5.24.36.s40.

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Poolsawat, S. S., and C. A. Huerta. "Acetaminophen: Abortifacient and embryocidal action." Proceedings, annual meeting, Electron Microscopy Society of America 44 (August 1986): 130–31. http://dx.doi.org/10.1017/s0424820100142293.

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Introduction. Chemical toxicity in the U.S. affects approximately 40% of the nation's 80 million workers who are exposed to toxic chemicals on a full or part-time bases. In 1980, about 40% of this workforce was comprised of women of childbearing ages. Considering such figure of a large number of women exposed to chemical toxins, it is a wonder that we have not had an epidemic of birth defects and organ abnormalities. A study has pointed that about 40% to 50% of all conceptions are eliminated before week 20 of gestation by way of a safety mechanism which helps to reduce the number of birth defects Acetaminophen, considered the safest of all over-the-counter analgesics, has been reported to induce fatal liver necrosis in man and animals.
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Hook, Ernest B. "Folic acid: Abortifacient or pseudoabortifacient?" American Journal of Medical Genetics 92, no. 5 (2000): 301–2. http://dx.doi.org/10.1002/1096-8628(20000619)92:5<301::aid-ajmg1>3.0.co;2-j.

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Hopson, Dana L., and Jennifer Ross. "Maternal Abortifacient use for Clandestine Abortion." Academic Forensic Pathology 6, no. 4 (2016): 663–72. http://dx.doi.org/10.23907/2016.062.

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Abortion is a highly debated topic. In the United States and other developed countries, the vast majority of abortions performed are done in a clinical setting or under the supervision of clinical staff. However, clandestine abortions still occur. Previously published reports have described clandestine abortions performed using crude and often dangerous methods. In the United States, published reports on the clandestine use of medications for abortions is rare. We report a series of cases in which maternal use of misoprostol and or a combination of misoprostol and mifepristone was used or suspected to have been used for the purpose of at-home pregnancy termination. These medications, purchased from Internet sites, were believed to have been shipped from countries outside of the United States. With ready accessibility to and increased prevalence of these sites on the Internet, it is likely that maternal abortifacient use will become more common in the future. This paper will provide guidance for the investigation and workup of these cases that come to the attention of the medical examiner or coroner.
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Colliton, William F. "Birth Control Pill: Abortifacient and Contraceptive." Linacre Quarterly 66, no. 4 (1999): 26–36. http://dx.doi.org/10.1080/20508549.1999.11877553.

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Dahm, D. "Abortifacient development should not be stifled." JAMA: The Journal of the American Medical Association 262, no. 13 (1989): 1876. http://dx.doi.org/10.1001/jama.262.13.1876.

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Dissertations / Theses on the topic "Abortifacient"

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Hughes, Susan Elizabeth. "Protective humoral immune responses against ovine abortifacient Chlamydia psittaci." Thesis, University of Edinburgh, 1998. http://hdl.handle.net/1842/29811.

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Breakdown of a native chlamydial vaccine against ovine enzootic abortion (OEA), coupled with the identification of the protective capacity of the major outer membrane protein (MOMP) of <I>C. psittaci, </I>has encouraged research into the use of recombinant forms of MOMP in a third generation OEA vaccine. The prospect of testing all recombinant forms of MOMP in pregnant sheep trials is a daunting one, both in terms of time and money. To circumvent these problems, it was decided that a model system would be required to assess the efficacies of recombinant MOMP constructs. The initial model developed (active immunisation of mice) did not appear to reflect immunisation in sheep. Difficulties were encountered in eliciting seroconversion in mice vaccinated with recombinant antigens. It also demonstrated a possible H-2 link to the MOMP-specific antibody response. Problems associated with the model were overcome to some extent, by the development of a second model (passive transfer of sheep sera to mice). In this case, it was demonstrated that infection of mice susceptible to <I>C. psittaci,</I> could be reduced by passively transferring sera from sheep which had been vaccinated with recombinant antigens. The mechanism of neutralisation <I>in vivo</I> was also examined for this model. The model was further used to identify protective regions within the MOMP by passive transfer of affinity purified antibodies and monoclonal antibodies. Significant protection was afforded by the VS1 and VS2 regions of the MOMP.
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Fiala, Christian. "Improving medical abortion : using mifepristone in combination with a prostaglandin analogue /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7140-458-9/.

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Aronsson, Annette. "Misoprostol - pharmacokinetics and effects on uterine contractility and cervical ripening in early pregnancy /." Stockholm : Karolinska institutet, 2007. http://diss.kib.ki.se/2007/978-91-7357-293-4/.

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Craig, Patrick Sylvester. "The effects of the abortifacient parasite, Neospora Caninum, on bovine foetuses in early and late gestation." Thesis, University of Liverpool, 2014. http://livrepository.liverpool.ac.uk/2002404/.

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Neospora caninum is an obligate intracellular protozoan parasite, which is the most frequently diagnosed abortifacient in dairy cattle in the UK and is a leading cause of abortion worldwide. Neospora caninum infection in early gestation is associated with foetal death whereas in late gestation, infection can result in the birth of asymptomatic, but persistently infected animals. How the parasite kills the foetus is not fully understood, but it has been suggested that more mature foetuses are better able to mount a stronger immune response to control parasite multiplication and dissemination. The ability of the bovine foetus to respond to various antigens develops in a sequential fashion during the gestation period and foetal immunocompetence starts to develop at approximately 100 days gestation age (dg), but can only fully recognise antigens during mid-gestation at around 150 dg. Chapter 2 assessed the pathological effects of N. caninum on bovine foetuses in early and late gestation (70 and 210 days gestation, respectively) and also in foetuses from naturally infected dams after recrudescence of N. caninum in mid to late gestation. Based on results of an initial histological screen of 35 bovine foetuses and 2 new-born calves, a total of 12 foetuses and calves were selected and subjected to more detailed histological examination. Both haemolymphatic and non-haemolymphatic tissues were used. The distribution of N. caninum antigen, CD3-positive T cells, PAX5-positive B cells, monocytes/macrophages and neutrophils (myeloid/histiocyte antigen/calprotectin-positive), antigen presenting cells (MHCII), interferon gamma (IFN-γ) expressing cells, PCNA-positive proliferating cells and apoptotic cells (cleaved caspase 3-positive) was analysed by immunohistology. In uninfected, control foetuses in early gestation (90 days gestation), haemolymphatic tissues were moderately developed and exhibited normal morphological features with low lymphocyte turn over and no evidence of IFN-γ production. Uninfected foetuses in late gestation had fully developed haemolymphatic tissues with high lymphocyte turnover, indicative of a mature immune system. In the infected foetuses in early gestation, extensive apoptosis of lymphocytes was observed in the thymus and spleen compared to controls (p<0.001, student’s t-test). No histological changes were observed in the haemolymphatic tissues of infected foetuses in late gestation. In non-haemolymphatic tissues, infected foetuses in early gestation exhibited extensive hepatocellular necrosis and apoptosis, glial cell necrosis and apoptosis in the CNS and high parasite loads in the liver, CNS and myocardium. There was no evidence of cell death in the heart despite the high parasite loads. In late gestation, histological lesions were restricted mainly to the CNS where non-suppurative inflammation and low parasite loads were observed. Other non-haemolymphatic tissues exhibited only mild mononuclear inflammatory infiltrates. The results suggest that in early gestation, tachyzoites replicate preferentially in foetal liver, brain and myocardium in the absence of an inflammatory response and cause extensive necrosis in the liver and brain. Unlike foetuses in early gestation, those in late gestation exhibited a mild to moderate mononuclear inflammatory infiltrate in various tissues dominated mainly by lymphocytes, plasma cells and smaller numbers of macrophages. In Chapter 3, the observation that N. caninum appeared to induce cellular degeneration in hepatocytes but not in the myocardium was investigated in more depth. An in vitro tissue culture system using the human HepG2 hepatoma cell line and the murine HL-1 cardiomyocyte cell line was used to establish the mechanism of cell death following N. caninum infection. The activation of the initiator and effector caspases (caspases 3, 8 and 9) was measured and the mitochondrial organisation in cells following N. caninum infection evaluated. Quantitative (caspase 3) and semi-quantitative (caspase 8 and 9) analyses were used to assess differences in N. caninum-infected and uninfected HepG2 and HL-1 cells. A significant difference was observed in the numbers of cleaved caspase 3-positive HepG2 cells at 20-36 hours post infection (p=0.029, Mann-Whitney U test) in infected cultures compared to controls. No significant difference was observed for caspase 8 and 9 expression. In HL-1 cultures, no significant difference was observed in the number of caspase 3, 8 and 9-positive cells between infected and control cultures. This suggests that N. caninum infection is not associated with activation of the caspase cascade in cardiomyocytes. Neospora caninum tachyzoites were detected within intact HepG2 and HL-1 cells with normal cellular morphology and which were not labelled with the caspase antibodies; whereas uninfected surrounding cells were caspase 3, 8 and 9-positive, indicating that the parasites are involved in the inhibition of the caspase pathways (intrinsic and extrinsic). The mitochondrial organisation in N. caninum-infected and uninfected cells was assessed in both cell lines using double immunofluorescence, which involved staining with a N. caninum specific polyclonal antibody and COX 1 mitochondrial marker. In the control cultures of both HepG2 and HL-1 cells, mitochondrial clumping with large aggregates of mitochondria exhibiting a punctate pattern was observed in high numbers of cells, mainly in the perinuclear region and this is suggestive of mitochondrial fragmentation, which is associated with apoptosis. Other cells within the control cultures revealed an unaltered reticular pattern of mitochondria that is consistent with the normal cellular morphology. In the infected cultures, there was mitochondrial clumping with aggregates of mitochondria detected surrounding parasitophorous vacuoles; while in neighbouring uninfected cells, large aggregates of mitochondria, exhibiting a punctate pattern were present, suggesting mitochondrial clumping and fragmentation associated with cytochrome c release and apoptosis. Other uninfected HepG2 and HL-1 cells exhibited a diffuse, homogenous distribution of mitochondria, often with an unaltered reticular pattern as was observed in the control cultures and is consistent with the normal cellular morphology. The results indicate that N. caninum inhibits apoptosis in infected cells and is associated with increased apoptosis in infected HepG2 cultures, while not having any effects on HL-1 cardiomyocytes. Chapter 4 investigated the seroprevalence of N. caninum infection in Jamaican dairy herds. Serum samples were analysed from 499 Holstein-Friesian and Holstein Friesian crossbreed dairy cattle from three different farms in Jamaica. A seroprevalence of approximately 26% was found with the majority of seropositive animals aged 0-2 years old (25%), while the lowest seroprevalence was recorded in animals over 13 years old (13.3%). Pregnancy status was shown to influence the seroprevalence of cows, but no significant relation of seropositivity to age was found, suggesting that vertical transmission is the principal route of transmission in Jamaica.
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Ngai, Suk-wai Cora. "Clinical applications of misoprostol in obstetrics and gynecology." Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B2180638X.

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倪淑慧 and Suk-wai Cora Ngai. "Clinical applications of misoprostol in obstetrics and gynecology." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2000. http://hub.hku.hk/bib/B31981720.

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Vaughan, ReBecca L. "Oppression breeds rebellion: herbal contraceptives and abortifacients and the role they fulfilled in allowing African American women to maintain their reproductive autonomy during slavery." DigitalCommons@Robert W. Woodruff Library, Atlanta University Center, 1997. http://digitalcommons.auctr.edu/dissertations/1363.

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This study examined the phenomena of herbal contraceptives and abortives and their use among enslaved women in the United States and the Caribbean. The conclusions that can be drawn from the research are that some women did choose to use herbal birth control and abortives. There is evidence to suggest that this use may have been directly used as a uniquely female means of resistance to slavery. It is also indicated that the more African cultural retentions there were in other areas of the lives of these women, the more likely that this phenomena would be employed as well. The profession of healer as a means of gaining respect and authority in the plantation community and in reference to how they aided women seeking abortions is discussed as well. The paper uses many historical sources as well as many science texts to authenticate the availability and properties of the flora and fauna of the regions in which women were enslaved. The author also postulates that this phenomena was aided by African retentions of these methods as well as additions by Native Americans upon arriving in North America and the Caribbean. Birth and death rates from a plantation are also used with three reproductive case studies of the women who lived on the plantation. Many slave narratives as well as contemporary sources were used in the research and writing of this paper.
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"Studies of the immunomodulatory and anti-tumour activities of three abortifacient proteins : α- & b- momorcharin and trichosanthin". Chinese University of Hong Kong, 1986. http://library.cuhk.edu.hk/record=b5895476.

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"Ribosome-inactivating proteins and abortifacient proteins: structure-activity studies." Chinese University of Hong Kong, 1988. http://library.cuhk.edu.hk/record=b5886212.

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Erbeck, Douglas H. "Abortifacient effect of Salmonella abortus-equi endotoxin in mice." 1988. http://hdl.handle.net/2097/22664.

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Books on the topic "Abortifacient"

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Z, Benet Leslie, Donaldson Molla S, Institute of Medicine (U.S.). Committee on Antiprogestins: Assessing the Science., and Institute of Medicine (U.S.). Division of Health Promotion and Disease Prevention., eds. Clinical applications of mifepristone (RU 486) and other antiprogestins: Assessing the science and recommending a research agenda. National Academy Press, 1993.

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WHO Scientific Group on Medical Methods for Termination of Pregnancy., ed. Medical methods for termination of pregnancy: Report of a WHO scientific group. World Health Organization, 1997.

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Conference on the Antiprogestational Compound RU 486 (1984 Bellagio, Italy). The antiprogestin steroid RU 486 and human fertility control. Plenum Press, 1985.

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Conférence internationale de consensus sur l'avortement par des méthodes non chirurgicales (médicales) au début du premier trimestre de la grossesse, sur des questions relatives aux schémas thérapeutiques et à la fourniture des services (2004 Bellagio, Italy). L'avortement médicamenteux: Questions cliniques les plus fréquentes. Organisation mondiale de la santé, 2008.

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United States. Congress. House. Committee on Small Business. Subcommittee on Regulation, Business Opportunities, and Energy. The safety and effectiveness of the abortifacient RU486 in foreign markets: Opportunities and obstacles to U.S. commercialization : hearing before the Subcommittee on Regulation, Business Opportunities, and Energy of the Committee on Small Business, House of Representatives, One Hundred Second Congress, first session, Washington, DC, December 5, 1991. U.S. G.P.O., 1992.

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1946-, Callahan Joan C., ed. Preventing birth: Contemporary methods and related moral controversies. University of Utah Press, 1989.

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Keller, Achim. Die Abortiva in der römischen Kaiserzeit. In Kommission, Deutscher apotheker Verlag, 1988.

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Taimat, Uni M. Herbal abortion: The fruit of the tree of knowledge. Sage-femme!, 1994.

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Costa, Caroline De. RU-486: The abortion pill. Boolarong Press, 2007.

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editor, Veldhuisa Suzanne, ed. Realidades y retos del aborto con medicamentos en México. El Colegio de la Frontera Sur, 2022.

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Book chapters on the topic "Abortifacient"

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Bygdeman, M. "Abortifacient Drugs." In Early Phase Drug Evaluation in Man. Macmillan Education UK, 1990. http://dx.doi.org/10.1007/978-1-349-10705-6_40.

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Baughman, Brittany. "Bovine Abortifacient and Teratogenic Toxins." In Bovine Reproduction. John Wiley & Sons, Inc., 2014. http://dx.doi.org/10.1002/9781118833971.ch65.

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Khan, Aisha Saleem. "Aphrodisiac and Abortifacient Activities of Important Trees." In Medicinally Important Trees. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-56777-8_8.

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Chan, Wood Yee, Jack Ho Wong, and Tzi Bun Ng. "Embryotoxic and Abortifacient Activities of Ribosome-inactivating Proteins." In Ribosome-inactivating Proteins. John Wiley & Sons, Ltd., 2014. http://dx.doi.org/10.1002/9781118847237.ch18.

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Sitruk-Ware, R., L. Billaud, I. Mowszowicz, et al. "The Use of RU 486 as an Abortifacient in Early Pregnancy." In The Antiprogestin Steroid RU 486 and Human Fertility Control. Springer US, 1985. http://dx.doi.org/10.1007/978-1-4684-1242-0_20.

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Taylor, De Shawn L., and Ronna Jurow. "Medical Abortifacients." In Management of Common Problems in Obstetrics and Gynecology. Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444323030.ch114.

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Hionidou, Violetta. "Emmenagogues and Abortifacients." In Abortion and Contraception in Modern Greece, 1830-1967. Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-41490-0_4.

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Schollaert, Jeannette. "Cultivating Access, Cultivating Ignorance: A Survey of Herbal Abortifacients in American Fiction." In The Palgrave Handbook of Reproductive Justice and Literature. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-99530-0_7.

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Bygdeman, M. "Abortifacient Drugs." In Early Phase Drug Evaluation in Man. CRC Press, 2020. http://dx.doi.org/10.1201/9780367812454-50.

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"abortifacient, n. & adj." In Oxford English Dictionary, 3rd ed. Oxford University Press, 2023. http://dx.doi.org/10.1093/oed/5413152840.

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Reports on the topic "Abortifacient"

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Misoprostol and teratogenicity: Reviewing the evidence. Population Council, 2003. http://dx.doi.org/10.31899/rh2003.1003.

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Misoprostol, a prostaglandin E1 analog marketed as Cytotec® for the prevention and treatment of gastric ulcers, is inexpensive and registered for use in over 80 countries. Many scientific articles show the preparation to be safe and effective for various reproductive health indications, including cervical softening and early pregnancy termination. Owing to the extensive body of published literature on these indications, misoprostol is now widely used for several reproductive health indications. The abortifacient properties of misoprostol are well known to medical professionals and frequently to the public. As noted in this meeting report, because the drug is available at low cost, many women have opted for self-administration of the method to terminate their pregnancies. The pharmaceutical industry and the public health community have raised the concern that if such an abortion attempt fails and the pregnancy results in a live birth, exposure of the fetus to misoprostol in utero could increase the risk of birth anomalies. The most extensively documented accounts of self-medication with misoprostol for induced abortion have come from Brazil, thus the case of Brazil provides a unique opportunity for studying the potential teratogenicity of misoprostol.
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