Relevant bibliographies by topics / Abrus precatorius

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  2. Dissertations / Theses
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  4. Conference papers

Academic literature on the topic 'Abrus precatorius'

Author: Grafiati
Published: 4 June 2021
Last updated: 7 September 2023

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Journal articles on the topic "Abrus precatorius"

1

Lal, A. B. "Abrus precatorius." Zeitschrift für Klassische Homöopathie 15, no. 03 (April 2, 2007): 101–6. http://dx.doi.org/10.1055/s-2006-937469.

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Okwute, Patrick Godwin, Gideon Olamilekan Oluwatunase, Adekunle M. Mofolorunso, Olayinka Olawale Asafa, Olubunmi Esther Ogunbiyi, and Samuel Olalekan. "Evaluation of <i>Abrus precatorius</i> on reproductive function of male Wistar rat." Anatomy Journal of Africa 12, no. 2 (August 17, 2023): 2384–92. http://dx.doi.org/10.4314/aja.v12i2.6.

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Background: In recent times, attention has been shifted from synthetic drugs to the use of medicinal plants and this has greatly improved reproductive functions. Abrus precatorious plant has different parts which are used as diverse sources of naturally occurring chemicals that have a variety of therapeutic effects on the body. However, in this present study, we consolidated the reproductive property of Abrus precatorius in paroxetine-induced male reproductive dysfunction. Methods: Twenty four (24) male rats were divided into four (4) groups each containing six animals was used for this experiment following paroxetine-induced erectile dysfunction. Group one, received 1ml of distilled water, Group two received 20mg/kg of Paroxetine and 50mg/kg of sildenafil, Group three received 20mg/kg of Paroxetine and 300mg/kg of A. precatorius extract, Group four received 20mg/kg of Paroxetine and 900mg/kg of A. precatorius extract for 21 days. Results: Results from the studies reveal that there was significant decrease in the sperm motility of the rats administered with Abrus precatorius when compared with control. Interestingly, the high dose extract increased the serum testosterone levels significantly while the low dose extract significantly reduce the level of testosterone when compared with the control. Histological examination of the testes of treated rats displayed noticeable atrophy, which was characterized by disruption of the seminiferous epithelium and reduction in cell population of the Leydig cells. Conclusion: It appears that very high dose of Abrus precatorius may induce infertility by increasing serum testosterone levels.
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Fotina, H. A., and M. T. Tion. "Pharmaco-toxicological properties of Abrus precatorius." Bulletin "Veterinary biotechnology" 32, no. 1 (2018): 291–302. http://dx.doi.org/10.31073/vet_biotech32(1)-38.

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Hovde, Blake T., Hajnalka E. Daligault, Erik R. Hanschen, Yuliya A. Kunde, Matthew B. Johnson, Shawn R. Starkenburg, and Shannon L. Johnson. "Detection of Abrin-Like and Prepropulchellin-Like Toxin Genes and Transcripts Using Whole Genome Sequencing and Full-Length Transcript Sequencing of Abrus precatorius." Toxins 11, no. 12 (November 25, 2019): 691. http://dx.doi.org/10.3390/toxins11120691.

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The sequenced genome and the leaf transcriptome of a near relative of Abrus pulchellus and Abrus precatorius was analyzed to characterize the genetic basis of toxin gene expression. From the high-quality genome assembly, a total of 26 potential coding regions were identified that contain genes with abrin-like, pulchellin-like, and agglutinin-like homology, with full-length transcripts detected in leaf tissue for 9 of the 26 coding regions. All of the toxin-like genes were identified within only five isolated regions of the genome, with each region containing 1 to 16 gene variants within each genomic region (<1 Mbp). The Abrus precatorius cultivar sequenced here contains genes which encode for proteins that are homologous to certain abrin and prepropulchellin genes previously identified, and we observed substantial diversity of genes and predicted gene products in Abrus precatorius and previously characterized toxins. This suggests diverse toxin repertoires within Abrus, potentially the results of rapid toxin evolution.
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Tokarnia, Carlos Hubinger, and Jürgen Döbereiner. "IMUNIDADE CRUZADA PELAS SEMENTES DE Abrus precatorius E Ricinus communis EM BOVINOS." Pesquisa Veterinária Brasileira 17, no. 1 (January 1997): 25–35. http://dx.doi.org/10.1590/s0100-736x1997000100005.

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Cinco bovinos imunizados contra a ação tóxica das sementes de Abrus precatorius L. ("tento", "jiquiriti") não adoeceram ou somente levemente pela administração das sementes de Ricinus communis L. ("mamona"), em doses que em bovinos que antes nunca ingeriram sementes de A. precatorius ou R. communis, causaram intoxicação de intensidade de grau moderado a acentuado ou até a morte. Um sexto bovino, que não ficou bem imunizado contra a ação tóxica das sementes de A. precatorius, adoeceu em grau acentuado pela administração de dose elevada das sementes de R. communis. Já dos cinco bovinos imunizados contra a ação tóxica das sementes de R. communis quatro adoeceram em grau acentuado, oquinto em grau moderado, pela administração das sementes de A. precatorias em doses que em bovinos que antes nunca ingeriram sementes de R. communis ou A. precatorius causaram intoxicação de intensidade leve a acentuada. Estes resultados permitem concluir que bovinos imunizados contra a ação tóxica das sementes de A. precatorius são resistentes à ação tóxica das sementes de R. communis, mas que o contrário não ocorre, isto é, bovinos imunizados contra a ação tóxica das sementes de R. communis, não se mostraram protegidos contra a intoxicação por A. precatorius. Estudos anteriores por outros autores mostraram que as toxalbuminas de A. precatorius e R. communis, respectivamente abrina e ricina, são diferentes do ponto de vista antigênico. Uma explicação para a divergência desses resultados com os nossos poderia estar no fato de que no presente estudo foram usados poligástricos que receberam as sementes por via oral, enquanto que nos estudos anteriores foram usados monogástricos em que as sementes ou as toxinas foram aplicadas por via parenteral. A administração de folhas frescas ou do pericarpo do fruto de R. communis a bovinos imunizados contra a ação das sementes desta planta tiveram o mesmo efeito tóxico que em animais não imunizados, demonstrando que a imunidade conferida pela ricina não inibe a ação da ricinina, o principio tóxico das folhas e do pericarpo.
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Aswin, Rafif Khairullah, Intan Solikhah Tridiganita, Nur Muhammad Ansori Arif, Amadea Puspitarani Gavrila, Dewi Anggraini Dina, and Ann Villar Posa Gabrielle. "Abrus precatorius: A comprehensive insight into the phytochemical, pharmacological, therapeutic activities and safety." Journal of Drug Delivery and Therapeutics 12, no. 1 (January 15, 2022): 151–57. http://dx.doi.org/10.22270/jddt.v12i1.5173.

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Abrus precatorius L., belonging to the family of Fabaceae is one of the potential herbal plants to be used as natural medicine. A. precatorius is capable of growing in tropical and subtropical areas of the world. The leaves of A. precatorius contain pinitol, triterpene glycosides, glycyrrhizin, and alkaloids. The leaves of A. precatorius can also treat leukoderma, skin diseases, itching, eye pain, and wounds. The seeds of A. precatorius contain flavonoids, steroids, alkaloids, anthocyanins, lectins, and fixed oils and can treat skin diseases, ulcers, and nervous system disorders. The roots of A. precatorius contain glycyrrhizin and alkaloid compounds and are able to treat rheumatism, alexiteric, sore throat, and vomiting. A. precatorius shows several therapeutic activities such as antimicrobial, anti-helminthics, antimalarial, antifungal, nephroprotective, immunomodulatory, neuromuscular, antidiabetic, anti-inflammatory, antifertility, antiserotonergic, antidiarrheal, antitumor, antispasmodic, and memory enhancing properties. Inappropriate dose of A. precatorius will cause toxic effects. Thus A. precatorius can be a good potential herbal plant to be used as a natural medicine. Keywords: Abrus precatorius, Fabaceae, Medicine, Pharmacology, Phytochemistry.
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Omhare, Namrata, Pratibha Sahu, Shailee Gautam, and Nidhi Jain. "Evaluation of hair growth promoting activity of petroleum ether extract of Abrus precatorius Linn. on Wistar Albino rats." Journal of Drug Delivery and Therapeutics 9, no. 2 (March 15, 2019): 330–35. http://dx.doi.org/10.22270/jddt.v9i2.2426.

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In present investigation was carried out to screening of hair growth promoting potentiality of petroleum ether extract of Abrus precatorius leaf. Preliminary chemical tests and TLC analysis revealed the presence flavonoids and saponins. Hair growth promoting activity of petroleum ether of Abrus precatorius was screened by considering different parameters which included time taken for covering bald patch, length of hair produced, percentage of hair follicles in anagen and telogen phases, time of hair growth initiation and completion and level of minerals in blood. The petroleum ether extract of Abrus precatorius showed a very good hair growth promoting activity at a dose of 300 mg/kg which was comparable to that of 2% minoxidil. After 30 days of treatment with test and standard drugs it was observed that, time taken for covering the bald patch, hair growth initiation and completion time and quantitative hair growth were found to be comparable to that of the standard drug. An increase in percentage of hair follicles turning from telogen phase to anagen phase was noted. The control treated group of animals showed poor hair growth for all the parameters. Keywords: Abrus precatorius Linn, Anagen, Catagen, Telogen, Minoxidil
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Worbs, Sylvia, Bettina Kampa, Martin Skiba, Eva-Maria Hansbauer, Daniel Stern, Hervé Volland, François Becher, Stéphanie Simon, Martin B. Dorner, and Brigitte G. Dorner. "Differentiation, Quantification and Identification of Abrin and Abrus precatorius Agglutinin." Toxins 13, no. 4 (April 18, 2021): 284. http://dx.doi.org/10.3390/toxins13040284.

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Abrin, the toxic lectin from the rosary pea plant Abrus precatorius, has gained considerable interest in the recent past due to its potential malevolent use. However, reliable and easy-to-use assays for the detection and discrimination of abrin from related plant proteins such as Abrus precatorius agglutinin or the homologous toxin ricin from Ricinus communis are sparse. To address this gap, a panel of highly specific monoclonal antibodies was generated against abrin and the related Abrus precatorius agglutinin. These antibodies were used to establish two sandwich ELISAs to preferentially detect abrin or A. precatorius agglutinin (limit of detection 22 pg/mL for abrin; 35 pg/mL for A. precatorius agglutinin). Furthermore, an abrin-specific lateral flow assay was developed for rapid on-site detection (limit of detection ~1 ng/mL abrin). Assays were validated for complex food, environmental and clinical matrices illustrating broad applicability in different threat scenarios. Additionally, the antibodies turned out to be suitable for immuno-enrichment strategies in combination with mass spectrometry-based approaches for unambiguous identification. Finally, we were able to demonstrate for the first time how the developed assays can be applied to detect, identify and quantify abrin from a clinical sample derived from an attempted suicide case involving A. precatorius.
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Ganesan, Rajeshkumar, and Rajalakshmi Ettiyan. "Abrus Precatorius Induced Hemorrhagic Colitis." American Journal of Pharmacology and Toxicology 10, no. 2 (February 1, 2015): 40–45. http://dx.doi.org/10.3844/ajptsp.2015.40.45.

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Mafra, Ana Isabela. "Capacidade de germinação de Abrus precatorius L. (Fabaceae) / Germination capacity of Abrus precatorius (Fabaceae)." Brazilian Journal of Animal and Environmental Research 4, no. 1 (2021): 116–41. http://dx.doi.org/10.34188/bjaerv4n1-012.

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Dissertations / Theses on the topic "Abrus precatorius"

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FERNANDES, Hélder Felício. "Bioensaio de extratos vegetais em Biomphalaria glabrata exposta a Schistosoma mansoni." Master's thesis, Instituto de Higiene e Medicina Tropical, 2015. http://hdl.handle.net/10362/19134.

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A schistosomose causada por Schistosoma mansoni é uma das parasitoses mais prevalentes em humanos, sendo o seu hospedeiro intermediário um molusco de água doce da espécie Biomphalaria glabrata. Para o controlo desta parasitose, além do tratamento dos doentes infetados, também é importante que as populações de moluscos sejam controladas. Visando encontrar estratégias de controlo dos moluscos, este estudo pretende clarificar o papel de alguns extratos vegetais enquanto inibidores do desenvolvimento do parasita na fase intra molusco. Neste contexto, o presente estudo teve como objetivo principal avaliar a atividade biológica de extratos de folhas de duas plantas da Guiné-Bissau (Abrus precatorius e Khaya senegalensis) sobre Biomphalaria glabrata infetada com Schistosoma mansoni. Os parâmetros avaliados foram a sobrevivência/mortalidade, oviposição, eliminação de cercárias e a sua viabilidade no hospedeiro definitivo (murganho), assim como a presença de danos no DNA dos moluscos através da técnica de Comet Assay. Embora os obtidos resultados sejam bastante preliminares, parecem indicar que os extratos de folhas de Abrus precatorius e Khaya senegalensis não apresentam atividade moluscicida uma vez que ocorreu uma baixa taxa mortalidade nos grupos de moluscos expostos aos extratos e esta ocorreu ao longo do bioensaio e não nas primeiras 24 horas de exposição. Através da técnica de Comet assay foi possível verificar que o DNA dos moluscos expostos aos extratos apresentava danos, mas não significativos. Em relação ao grupo de moluscos infetados com S.mansoni e expostos aos extratos, só os que foram expostos ao extrato de A. precatorius e a DMSO apresentaram danos significativos no DNA. No que diz respeito à libertação de cercárias demonstrou que a exposição aos extratos induziu uma maior libertação de cercárias por parte dos moluscos quando comparativamente ao grupo de moluscos só infetados com S.mansoni ,no entanto estas diferenças não se apresentam como significativas. Em relação à oviposição, os extratos em si parecem não ser responsáveis pelo aumento do número médio de posturas produzidas por B.glabrata. Embora tenham existido diferenças no número médio de posturas produzidas entre os vários grupos experimentais, estas só foram significativas no grupo de moluscos infetados e expostos ao extrato de K.senegalensis e no grupo de moluscos infetados mas não expostos a nenhum extrato (neste caso no controlo para os moluscos expostos ao extrato de K. senegalensis). Por outro lado, os extratos parecem afetar a viabilidade das formas infetantes, quer para o hospedeiro definitivo (cercárias), quer para o hospedeiro intermediário (miracídios).
Schistosomiasis, caused by Schistosoma mansoni, is one of the most prevalent parasitic diseases in humans, its intermediate host is a freshwater mollusc from the species Biomphalaria glabrata. For the control of this disease, besides treatment of infected patients, it is also important that the mollusc populations are controlled. In order to find strategies for control of molluscs, this study aimed to investigate the activity of plant extracts as inhibitors of parasite development in mollusc. The main objective was to evaluate the biological activity of extracts from the leaves of two plants from Guinea-Bissau (Abrus precatorius and Khaya senegalensis) in Biomphalaria glabrata exposed to Schistosoma mansoni. The parameters evaluated were survival / mortality, oviposition, elimination of cercariae and its viability on the definitive host (mouse) as well as DNA damage in the molluscs through the technique of Comet Assay. Although the results are very preliminary, they seem to indicate that the extracts from leaves of Abrus precatorius and Khaya senegalensis don’t have molluscicidal activity, as the mortality rate was low in the groups of molluscs exposed to the extracts and mortality occurred later in the bioassay and not during the first 24 hours post-exposure. Through the technique of Comet assay we found that the DNA from molluscs exposed to extracts showed damage but that it was not significant. Regarding the group of molluscs infected with S.mansoni and exposed to the extracts, only those exposed to the extract of A. precatorius and DMSO showed significant DNA damage. Exposure to extracts induced an increase in the release of cercariae by the molluscs when compared to the group of molluscs infected only with S.mansoni, however these differences were not statistically significant. It was not detected an increase in the average number of eggs produced by B.glabrata exposed to the extracts. Although there were differences in the mean number of eggs produced between the various experimental groups, they were only significant between the group of molluscs infected and exposed to the extract from Khaya senegalensis and in the group infected but not exposed to any of the extracts (specifically in the control for the molluscs exposed to the extract of Khaya senegalensis). On the other hand the extracts appear to affect the viability of the infective forms in the definitive host (cercariae), and in the intermediate host (miracidia).
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Rival, Alain. "Cinétique de la nutrition minérale et métabolisme du carbone et de l'azote dans des suspensions cellulaires hétérotrophes et photomixotrophes : aspects physiologiques et biochimiques chez Abrus precatorius L. (Leguminosae)." Montpellier 2, 1989. http://www.theses.fr/1989MON20079.

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Dans le but de cerner in vitro l'impact de la photosynthese sur les voies metaboliques essentielles, un souchier de lignees cellulaires photomixotrophes & heterotrophes a ete etabli, sous forme de cals et de suspensions cellulaires, pour une plante medicinale tropicale: abrus precatorius l. (leguminosae). La consommation, en cours de culture, des macroelements majeurs du milieu (no#3, nh#4, pi, so#4) a ete mesuree. Cette etude a permis de mettre en evidence des differentes importantes entre les besoins nutritionnels pour chaque element. De plus, une caracterisation partielle de deux enzymes impliquees dans l'assimilation de l'azote mineral: nitrate reductase & glutamine synthetase, a ete realisee. Afin de mieux connaitre les phenomenes biochimiques lies a la photomixotrophie, l'activite de deux carboxylases (ribulose 1,5 bisphosphate carboxylase -rubisco- & phosphoenolpyruvate carboxylase -pepc-) a ete mesuree sur les suspensions cellulaires. Nous avons suivi l'activite de ces 4 systemes enzymatiques (nr, gs, rubisco & pepc) au cours de cultures conduites sous differentes conditions (hetero/mixotrophie) a l'aide de deux systemes de culture (erlenmeyers ou bioreacteur experimental). Cette etude est completee par une caracterisation immunologique de ces enzymes, permettant de degager quelques donnees concernant leur biosynthese et leur regulation
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Sánchez, Vanessa. "Characterization of Rhizobial Diversity and Relationship of Rhizobial Partner and Legume Performance in Four South Florida Pine Rockland Soils." FIU Digital Commons, 2014. http://digitalcommons.fiu.edu/etd/1124.

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Pine rocklands are endangered ecosystems unique to south Florida, the Bahamas and Cuba. As a result of their karstic calcium carbonate­rich soil, these systems are limited in phosphorus and nitrogen, making symbiotic associations critical to plant growth. Four leguminous species (Cajanus cajan, Chamaecrista fasciculata, Tephrosia angustissima, and Abrus precatorious) were used to determine the relationship between rhizobial partners and plant performance, and the symbiosis related gene nifH was amplified to characterize the diversity of rhizobial symbionts. Plants were grown in soils from four different south Florida pine rocklands, and a salinity treatment was added to determine how storm surge and sea level rise could affect this symbiotic relationship. While plant performance and nodulation were highly impacted by soil type, salinity did not represent a significant effect. Phylogenetic analysis determined that all four plant species were found to associate with Bradyrhizobium spp. and no rhizobial shift between salinity treatment and soil type was found.
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Wang, Xi Xian, and 王錫賢. "The complete amino acid sequence and partial genomic DNA of abrus precatorius trypsin inhibitor isolated from abrus precatorius." Thesis, 1996. http://ndltd.ncl.edu.tw/handle/23350258996979265189.

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碩士
國立臺灣大學
生化學研究所
84
A protease inhibitor was isolated from the seeds of Abrus precatorius using ion exchang chromatography on DEAE-cellulose, gel filtration on Sephadex G-75 and affinity chromatography on immobilized trypsin.The purified inhibitor is a Bowman-Birk type and designated as APTI. APTI is a double-headed protease inhibitor because it inhi- bits both the trypsin and chymotrypsin activities.The complete amino acid sequence was deduced from the analysis of peptides derived from the reduced and S-carboxymethylated protein by cleaving lysyl endopeptidase and thermolysin.This inhibitor com- prises 77 amino acid residues including seven disulfide bridges. The putative reactive inhibitor sites of APTI are at Lys(27)-Ser (28) and Leu(52)-Ser(53) for trypsin and chymotrypsin,respectively .The amino acid sequence,the invariant amino acid residues and the reactive inhibitor sites of APTI resemble to those of the Bowman- Birk double-headed protease inhibitor.APTI consists of four anti- parallel structures and probably formed by two tandem repeat domains.
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Mishra, Abhipsa. "Isolation and characterization of lectins from white seeds of Abrus precatorius." Thesis, 2012. http://ethesis.nitrkl.ac.in/3111/1/Soma-Abrus_Dtd.7.05.12.pdf.

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The present study indicates that Abrus precatorius was found to be the potential source for lectins. The lectin called Abrus agglutinin was isolated and characterized from white Abrus seed by the lactamyl sepharose 4B chromatography followed by SDS-PAGE. Lectin bind with the sepharose bead and it was separated out by the process of dialysis. The concentration of protein was measured. Agglutinins are sensitive to RBC of blood. Haemagglutination assay is another method for tittering protein based on their ability to attach to molecules present on the surface of red blood cells. The protein was identified by the Sodium Dodecyl Sulphate Polyacrylamide Gel Electrophoresis. The relative molecular weight of agglutinin was found 33kDa, 29kDa which corresponds to A chain and B chain of Agglutinin.
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Prasad, Sneha. "Isolation and characterization of lectins from red seeds of Abrus precatorius." Thesis, 2012. http://ethesis.nitrkl.ac.in/3112/1/Sneha-Abrus_Dtd.7.05.2012.pdf.

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The study was done to isolate lectin from red seeds of Abrus precatorius. The protein was purified by using affinity chromatography. The activity of the lectin was determined by haemagglutinin assay and the purity of the protein was tested by Sodium dodecyl sulphate Polyacrylamide Gel Electrophoresis (SDS-PAGE). The activity of lectins is quantified by their ability to agglutinate erythrocyte. The eluted protein exhibited agglutinating activity when reacted against different types of fresh erythrocytes. In SDS-PAGE in affinity 2 bands were observed of 34kD and 31kD of heterotetrameric agglutinin.
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Liu, Chao-Lin, and 劉昭麟. "Abrus Agglutinin from Abrus precatorius： Primary Structure, and Function Analysis of the A Chain by Site-Directed Mutagenesis." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/04027651685711115293.

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博士
國立臺灣大學
生化學研究所
88
Abrus agglutinin (AAG), a low-toxicity protein from the plant Abrus precatorius, is less lethal than abrina (ABRa) in mice (LD50, 5 mg/kg vs. 20 μg/kg body weight). The nucleotide sequence analysis of a cDNA clone encoding the full-length AAG showed an open reading frame with 1,641 base pairs, corresponding to 547 amino acid residue preproprotein containing a signal peptide and a linker region (2 amino acid residues) between AAG-A and AAG-B subunits. AAG had high homology to ABRa (77.8 %). The 13 amino acid residues involved in catalytic function, which are highly conserved among ABRs and ricins, were also conserved within AAG-A. The protein synthesis inhibitiory activity of AAG-A (IC50, 3.5 nM) was weaker than that of ABRa-A (0.05 nM). Molecular modeling followed by site-directed mutagenesis showed that IC50 of ABRa-A (N200P) and AGG-A (P199N) was dretemined to be 2.3 nM and 0.53 nM, respectively. It suggested that the Pro199 residue of AAG-A, located in the amphiphilic helix H and corresponding to the Asn200 residue of ABRa-A, can induce bending of helix H. This bending would presumably affect the binding of AAG-A to its target sequence, GpApGpAp, in the tetraloop structure of the 28S rRNA subunit and could be one of the major factors contributing to the relatively weak protein synthesis inhibitory activity and toxicity of AAG.
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Falcão, Justiniano Ferreira. "Contribuição para os estudos fitoquímico e de actividade biológica de Abrus precatorius L." Master's thesis, 2007. http://hdl.handle.net/10451/233.

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Tese de mestrado em Química Farmacêutica e Terapêutica apresentada à Universidade de Lisboa através da Faculdade de Farmácia, 2007
O presente estudo foi efectuado sobre Abrus precatorius L., Fabaceae, originária da Ásia, que se encontra difundida em várias regiões tropicais e subtropicais do globo onde a planta tem vários usos etnobotânicos incluindo etnomédicos e teve como objectivo contribuir para o aprofundamento do seu estudo químico e biológico, tendo, neste âmbito, sido efectuado um estudo fitoquímico bioguiado por ensaios de actividade antimicrobiana sobre as raízes e um estudo fitoquímico sobre as folhas desta espécie, colhidas na Guiné-Bissau. Foi demonstrada a actividade antimicrobiana in vitro contra Enterococcus faecalis, Staphylococcus aureus, Candida albicans e Cladosporium cucumerinum de um extracto clorofórmico das raízes. O estudo bioguiado deste extracto permitiu localizar três dos constituintes total ou parcialmente responsáveis pela actividade biológica do extracto, tendo em sequência sido identificados dois deles, a abruquinona A e B. Estes compostos mostraram-se activos contra os quatro microrganismos supramencionados e também contra Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Shigella dysenteriae e Vibrio cholerae. Staphylococcus aureus foi a bactéria contra a qual o extracto e as abruquinonas A e B mostraram maior actividade. Para além destes dois compostos foi também identificado o alcalóide abrina nesta parte da planta. Nas folhas de A. precatorius foram identificados dois dos constituintes maioritários, o abrusósido C e abrusósido D e também o alcalóide trigonelina. Foram também isolados e são propostas estruturas para dois constituintes ainda não descritos nesta espécie, pertencentes à classe dos flavonóides, nomeadamente ao grupo das flavonas metiladas, o qual é caracterizado pelas suas interessantes actividades biológicas.
The here presented study is a contribution to a deeper chemical and biological knowledge of Abrus precatorius L. - a Fabaceae originated from Asia and widespread throughout several tropical and sub-tropical regions. Different ethnobotanical uses have been reported for this species, ethnomedical uses included. Results of our phytochemical study on the roots of Abrus precatorius, collected in Guiné-Bissau, showed the in vitro antibacterial activity of its chloroform extract against Enterococcus faecalis and Staphylococcus aureus and its in vitro antifungical activity against Candida albicans and Cladosporium cucumerinum. A bioguided study of this extract, by means of antimicrobial activity assays, allowed the isolation of three components total or partially responsible for its biological activity, two of them later identified as abruquinone A and abruquinone B. These compounds were active not only against the above mentioned four microorganisms, but also against Escherichia coli, Pseudomonas aeruginosa, Salmonella typhimurium, Shigella dysenteriae and Vibrio cholerae. The greatest activity revealed both by the extract and the abruquinones A e B was against Staphylococcus aureus. We have also identified the alkaloid abrine in this plant part. Results of our phytochemical study on the leaves of Abrus precatorius, also collected in Guiné-Bissau, allowed the identification of two major components - abrusoside C and abrusoside D as well as the alkaloid trigonelline. We have also isolated two other methylated flavones not yet described in this species, of which we hereby propose the structures.
Fundação Calouste Gulbenkian (FCG) e Centro de Estudos de Ciências Farmacêuticas da Faculdade de Farmácia da Universidade de Lisboa (financiamento do projecto de Investigação no âmbito do programa de Financiamento Plurianual das Unidades de ID da Fundação para a Ciência e a Tecnologia).
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Vishwakarma, Kavita. "Green synthesis of ZnO nanoparticles using abrus precatorius seeds extract and their characterization." Thesis, 2013. http://ethesis.nitrkl.ac.in/5012/1/411LS2069.pdf.

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In modern science Nanotechnology is a ablaze field for the researchers.Nanoparticles having a size of 1-100 nm in one dimension, is used significantly concerning medical chemistry, atomic physics, and all other known fields. Nanoparticles are used immensely due to its small size, orientation, physical properties,which are reportedly shown to change the performance of any other material which is in contact with these tiny particles. These particles can be prepared easily by different chemical, physical, and biological approaches. But the biological approach is the most emerging approach of preparation, because, this method is easier than the other methods, ecofriendly and less time consuming. The semiconductor ZnO has gained substantial interest in the research community in part because of its large exciton binding energy 60 meV which could lead to lasing action based on exciton recombination even above room temperature. The Green synthesis was done by using the aqueous solution of Abrus precatorius seeds extract and zinc acetate. A fixed ratio of plant extract to metal ion was prepared and the color change was observed which proved the formation of nanoparticles. The nanoparticles were characterized by UV-vis Spectrophotometer, FTIR, DLS, Zeta Analysis, XRD, and SEM. The particles synthesized were of the size ranging from 90-500 nm.
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HUANG, SHU-GING, and 黃淑卿. "Study on the toxic proteins of abrus precatorius as inducer of tumor necrosis factor." Thesis, 1986. http://ndltd.ncl.edu.tw/handle/27856584636876241572.

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碩士
台北醫學院
藥學研究所
74
BCG ，OK-432等免疫增強劑，能刺激活化巨噬細胞之抗癌作用，已受今日醫藥界之矚 目。1975年美國Sloan Kettering 研究所之Dr. L. J. Old 及E. A. Carswell等，首 先報告腫瘤壞死因子（Tumor Necrosis Factor; TNF）會引起腫瘤細胞壞死，進而使 腫瘤消失。 雞母珠血球凝集素（Abrus Agglutinin；AAG ）及雞母珠毒蛋白（Abrin ；Ab），於 1970年代即被證明具有抗癌作用，其抗癌機制，除直接細胞毒外，尚可加強免疫機能 ，可知雞母珠為一特殊抗癌物質，但毒性太大，至今尚未用於臨床。TNF 沒有種之特 異性，且對正常細胞沒有毒性，倘能經由雞母珠誘導TNF 應用於臨床，將有助於抗癌 新藥之開發及植物資源之利用。 本研究分三部份：1.經由體內生物檢定，探討雞母珠毒蛋白誘發腫瘤壞死因子之活性 ，及其最低腫瘤壞死條件。2.經由驗外細胞毒檢定方式，探討TNS 之誘導機制，及其 TNS 活性之力價，同時設定一經濟省時之實驗方法。3.TNS 對肝功能和末稍血液白血 球分類之影響。 由本研究得知AAG 可當第一刺激物質priming agent ，Ab可當第二刺激物（elicitin g agent ）誘導產生TNF ，其導致最佳腫瘤壞死條件為AAG 200ng/mouse ，Ab 20ng/ mouse ，Ab給予2 小時後採血，以0.4ml 之血清，靜脈注射至擔癌老鼠，可得最明顯 腫瘤壞死現象，且TNF 無種之特異性，對肝功能及末稍血球中沐巴球百分比無明顯差 異，而其體外百分之五十細胞毒之力價為26LU/ml 。 本研究以AAG 、Ab誘導TNF 類物質，但此物質是否與Old 所報導之TNF 為同一物質， 需更進一步純化及生化特性之確認。
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Book chapters on the topic "Abrus precatorius"

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Khare, C. P. "Abrus precatorius Linn." In Indian Medicinal Plants, 1. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-70638-2_5.

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Sastry, K. Subramanya, Bikash Mandal, John Hammond, S. W. Scott, and R. W. Briddon. "Abrus precatorius (Jequirity)." In Encyclopedia of Plant Viruses and Viroids, 14. New Delhi: Springer India, 2019. http://dx.doi.org/10.1007/978-81-322-3912-3_4.

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Ross, Ivan A. "Abrus precatorius L." In Medicinal Plants of the World, 15–31. Totowa, NJ: Humana Press, 2003. http://dx.doi.org/10.1007/978-1-59259-365-1_2.

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Devanathan, Krishnamoorthy. "Abrus precatorius L. Fabaceae." In Ethnobotany of Mountain Regions, 1–11. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-14116-5_101-1.

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Devanathan, Krishnamoorthy. "Abrus precatorius L. Fabaceae." In Ethnobotany of Mountain Regions, 31–41. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-38389-3_101.

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Shah, Mansi, K. Meenakshi, and Indu Anna George. "Abrus precatorius (Rosary Pea)." In Exploring Poisonous Plants, 87–99. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/b23017-7.

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Akbar, Shahid. "Abrus precatorius L. (Fabaceae/Leguminosae)." In Handbook of 200 Medicinal Plants, 21–32. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-16807-0_3.

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Patil, Avinash, Sonali Patil, and Darshana Patil. "Phytochemistry and Pharmacology of Abrus precatorius L." In Bioactives and Pharmacology of Legumes, 79–99. New York: Apple Academic Press, 2023. http://dx.doi.org/10.1201/9781003304555-6.

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Sur, Pratima, and Dilip K. Ganguly. "Abrus (A. precatorius L.) Leaf Extract as a Novel Antitumor Agent." In Food Factors for Cancer Prevention, 286–89. Tokyo: Springer Japan, 1997. http://dx.doi.org/10.1007/978-4-431-67017-9_57.

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"Abrus precatorius." In A Guide to Poisonous House and Garden Plants, 1–2. Teton NewMedia, 2007. http://dx.doi.org/10.1201/b16160-2.

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Conference papers on the topic "Abrus precatorius"

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Agustina, R., A. H. Cahyana, and R. R. Tjandrawinata. "Abrine (N-methyltryptophan), an alkaloid from Abrus precatorius Linn. leaves extract." In PROCEEDINGS OF THE 5TH INTERNATIONAL SYMPOSIUM ON CURRENT PROGRESS IN MATHEMATICS AND SCIENCES (ISCPMS2019). AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0007888.

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