Journal articles: 'Abrus precatorius'

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Lal, A. B. "Abrus precatorius." Zeitschrift für Klassische Homöopathie 15, no. 03 (April 2, 2007): 101–6. http://dx.doi.org/10.1055/s-2006-937469.

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Okwute, Patrick Godwin, Gideon Olamilekan Oluwatunase, Adekunle M. Mofolorunso, Olayinka Olawale Asafa, Olubunmi Esther Ogunbiyi, and Samuel Olalekan. "Evaluation of <i>Abrus precatorius</i> on reproductive function of male Wistar rat." Anatomy Journal of Africa 12, no. 2 (August 17, 2023): 2384–92. http://dx.doi.org/10.4314/aja.v12i2.6.

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Background: In recent times, attention has been shifted from synthetic drugs to the use of medicinal plants and this has greatly improved reproductive functions. Abrus precatorious plant has different parts which are used as diverse sources of naturally occurring chemicals that have a variety of therapeutic effects on the body. However, in this present study, we consolidated the reproductive property of Abrus precatorius in paroxetine-induced male reproductive dysfunction. Methods: Twenty four (24) male rats were divided into four (4) groups each containing six animals was used for this experiment following paroxetine-induced erectile dysfunction. Group one, received 1ml of distilled water, Group two received 20mg/kg of Paroxetine and 50mg/kg of sildenafil, Group three received 20mg/kg of Paroxetine and 300mg/kg of A. precatorius extract, Group four received 20mg/kg of Paroxetine and 900mg/kg of A. precatorius extract for 21 days. Results: Results from the studies reveal that there was significant decrease in the sperm motility of the rats administered with Abrus precatorius when compared with control. Interestingly, the high dose extract increased the serum testosterone levels significantly while the low dose extract significantly reduce the level of testosterone when compared with the control. Histological examination of the testes of treated rats displayed noticeable atrophy, which was characterized by disruption of the seminiferous epithelium and reduction in cell population of the Leydig cells. Conclusion: It appears that very high dose of Abrus precatorius may induce infertility by increasing serum testosterone levels.

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Fotina, H. A., and M. T. Tion. "Pharmaco-toxicological properties of Abrus precatorius." Bulletin "Veterinary biotechnology" 32, no. 1 (2018): 291–302. http://dx.doi.org/10.31073/vet_biotech32(1)-38.

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Hovde, Blake T., Hajnalka E. Daligault, Erik R. Hanschen, Yuliya A. Kunde, Matthew B. Johnson, Shawn R. Starkenburg, and Shannon L. Johnson. "Detection of Abrin-Like and Prepropulchellin-Like Toxin Genes and Transcripts Using Whole Genome Sequencing and Full-Length Transcript Sequencing of Abrus precatorius." Toxins 11, no. 12 (November 25, 2019): 691. http://dx.doi.org/10.3390/toxins11120691.

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The sequenced genome and the leaf transcriptome of a near relative of Abrus pulchellus and Abrus precatorius was analyzed to characterize the genetic basis of toxin gene expression. From the high-quality genome assembly, a total of 26 potential coding regions were identified that contain genes with abrin-like, pulchellin-like, and agglutinin-like homology, with full-length transcripts detected in leaf tissue for 9 of the 26 coding regions. All of the toxin-like genes were identified within only five isolated regions of the genome, with each region containing 1 to 16 gene variants within each genomic region (<1 Mbp). The Abrus precatorius cultivar sequenced here contains genes which encode for proteins that are homologous to certain abrin and prepropulchellin genes previously identified, and we observed substantial diversity of genes and predicted gene products in Abrus precatorius and previously characterized toxins. This suggests diverse toxin repertoires within Abrus, potentially the results of rapid toxin evolution.

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Tokarnia, Carlos Hubinger, and Jürgen Döbereiner. "IMUNIDADE CRUZADA PELAS SEMENTES DE Abrus precatorius E Ricinus communis EM BOVINOS." Pesquisa Veterinária Brasileira 17, no. 1 (January 1997): 25–35. http://dx.doi.org/10.1590/s0100-736x1997000100005.

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Cinco bovinos imunizados contra a ação tóxica das sementes de Abrus precatorius L. ("tento", "jiquiriti") não adoeceram ou somente levemente pela administração das sementes de Ricinus communis L. ("mamona"), em doses que em bovinos que antes nunca ingeriram sementes de A. precatorius ou R. communis, causaram intoxicação de intensidade de grau moderado a acentuado ou até a morte. Um sexto bovino, que não ficou bem imunizado contra a ação tóxica das sementes de A. precatorius, adoeceu em grau acentuado pela administração de dose elevada das sementes de R. communis. Já dos cinco bovinos imunizados contra a ação tóxica das sementes de R. communis quatro adoeceram em grau acentuado, oquinto em grau moderado, pela administração das sementes de A. precatorias em doses que em bovinos que antes nunca ingeriram sementes de R. communis ou A. precatorius causaram intoxicação de intensidade leve a acentuada. Estes resultados permitem concluir que bovinos imunizados contra a ação tóxica das sementes de A. precatorius são resistentes à ação tóxica das sementes de R. communis, mas que o contrário não ocorre, isto é, bovinos imunizados contra a ação tóxica das sementes de R. communis, não se mostraram protegidos contra a intoxicação por A. precatorius. Estudos anteriores por outros autores mostraram que as toxalbuminas de A. precatorius e R. communis, respectivamente abrina e ricina, são diferentes do ponto de vista antigênico. Uma explicação para a divergência desses resultados com os nossos poderia estar no fato de que no presente estudo foram usados poligástricos que receberam as sementes por via oral, enquanto que nos estudos anteriores foram usados monogástricos em que as sementes ou as toxinas foram aplicadas por via parenteral. A administração de folhas frescas ou do pericarpo do fruto de R. communis a bovinos imunizados contra a ação das sementes desta planta tiveram o mesmo efeito tóxico que em animais não imunizados, demonstrando que a imunidade conferida pela ricina não inibe a ação da ricinina, o principio tóxico das folhas e do pericarpo.

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Aswin, Rafif Khairullah, Intan Solikhah Tridiganita, Nur Muhammad Ansori Arif, Amadea Puspitarani Gavrila, Dewi Anggraini Dina, and Ann Villar Posa Gabrielle. "Abrus precatorius: A comprehensive insight into the phytochemical, pharmacological, therapeutic activities and safety." Journal of Drug Delivery and Therapeutics 12, no. 1 (January 15, 2022): 151–57. http://dx.doi.org/10.22270/jddt.v12i1.5173.

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Abrus precatorius L., belonging to the family of Fabaceae is one of the potential herbal plants to be used as natural medicine. A. precatorius is capable of growing in tropical and subtropical areas of the world. The leaves of A. precatorius contain pinitol, triterpene glycosides, glycyrrhizin, and alkaloids. The leaves of A. precatorius can also treat leukoderma, skin diseases, itching, eye pain, and wounds. The seeds of A. precatorius contain flavonoids, steroids, alkaloids, anthocyanins, lectins, and fixed oils and can treat skin diseases, ulcers, and nervous system disorders. The roots of A. precatorius contain glycyrrhizin and alkaloid compounds and are able to treat rheumatism, alexiteric, sore throat, and vomiting. A. precatorius shows several therapeutic activities such as antimicrobial, anti-helminthics, antimalarial, antifungal, nephroprotective, immunomodulatory, neuromuscular, antidiabetic, anti-inflammatory, antifertility, antiserotonergic, antidiarrheal, antitumor, antispasmodic, and memory enhancing properties. Inappropriate dose of A. precatorius will cause toxic effects. Thus A. precatorius can be a good potential herbal plant to be used as a natural medicine. Keywords: Abrus precatorius, Fabaceae, Medicine, Pharmacology, Phytochemistry.

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Omhare, Namrata, Pratibha Sahu, Shailee Gautam, and Nidhi Jain. "Evaluation of hair growth promoting activity of petroleum ether extract of Abrus precatorius Linn. on Wistar Albino rats." Journal of Drug Delivery and Therapeutics 9, no. 2 (March 15, 2019): 330–35. http://dx.doi.org/10.22270/jddt.v9i2.2426.

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In present investigation was carried out to screening of hair growth promoting potentiality of petroleum ether extract of Abrus precatorius leaf. Preliminary chemical tests and TLC analysis revealed the presence flavonoids and saponins. Hair growth promoting activity of petroleum ether of Abrus precatorius was screened by considering different parameters which included time taken for covering bald patch, length of hair produced, percentage of hair follicles in anagen and telogen phases, time of hair growth initiation and completion and level of minerals in blood. The petroleum ether extract of Abrus precatorius showed a very good hair growth promoting activity at a dose of 300 mg/kg which was comparable to that of 2% minoxidil. After 30 days of treatment with test and standard drugs it was observed that, time taken for covering the bald patch, hair growth initiation and completion time and quantitative hair growth were found to be comparable to that of the standard drug. An increase in percentage of hair follicles turning from telogen phase to anagen phase was noted. The control treated group of animals showed poor hair growth for all the parameters. Keywords: Abrus precatorius Linn, Anagen, Catagen, Telogen, Minoxidil

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Worbs, Sylvia, Bettina Kampa, Martin Skiba, Eva-Maria Hansbauer, Daniel Stern, Hervé Volland, François Becher, Stéphanie Simon, Martin B. Dorner, and Brigitte G. Dorner. "Differentiation, Quantification and Identification of Abrin and Abrus precatorius Agglutinin." Toxins 13, no. 4 (April 18, 2021): 284. http://dx.doi.org/10.3390/toxins13040284.

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Abrin, the toxic lectin from the rosary pea plant Abrus precatorius, has gained considerable interest in the recent past due to its potential malevolent use. However, reliable and easy-to-use assays for the detection and discrimination of abrin from related plant proteins such as Abrus precatorius agglutinin or the homologous toxin ricin from Ricinus communis are sparse. To address this gap, a panel of highly specific monoclonal antibodies was generated against abrin and the related Abrus precatorius agglutinin. These antibodies were used to establish two sandwich ELISAs to preferentially detect abrin or A. precatorius agglutinin (limit of detection 22 pg/mL for abrin; 35 pg/mL for A. precatorius agglutinin). Furthermore, an abrin-specific lateral flow assay was developed for rapid on-site detection (limit of detection ~1 ng/mL abrin). Assays were validated for complex food, environmental and clinical matrices illustrating broad applicability in different threat scenarios. Additionally, the antibodies turned out to be suitable for immuno-enrichment strategies in combination with mass spectrometry-based approaches for unambiguous identification. Finally, we were able to demonstrate for the first time how the developed assays can be applied to detect, identify and quantify abrin from a clinical sample derived from an attempted suicide case involving A. precatorius.

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Ganesan, Rajeshkumar, and Rajalakshmi Ettiyan. "Abrus Precatorius Induced Hemorrhagic Colitis." American Journal of Pharmacology and Toxicology 10, no. 2 (February 1, 2015): 40–45. http://dx.doi.org/10.3844/ajptsp.2015.40.45.

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Mafra, Ana Isabela. "Capacidade de germinação de Abrus precatorius L. (Fabaceae) / Germination capacity of Abrus precatorius (Fabaceae)." Brazilian Journal of Animal and Environmental Research 4, no. 1 (2021): 116–41. http://dx.doi.org/10.34188/bjaerv4n1-012.

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Iyekowa, Osaro, and Opara V. Ndubuisi. "Phytochemical Constituents, Haematological Activities and GC-MS Analysis of Isolated Oil of Rosary Pea (Abrus precatorius) in Wistar Rat Fed with High Lipid Diet." Tanzania Journal of Science 48, no. 4 (December 30, 2022): 863–74. http://dx.doi.org/10.4314/tjs.v48i4.13.

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The study is aimed at investigating the phytochemical constituents and haematological activities of the isolated oil in Wistar rat fed with high lipid diet. Powdered leaves of Abrus precatorious were extracted and phytochemical screening was done according to prescribed standard methods, while vacuum liquid chromatography (VLC) was adopted for oil isolation of the crude extract and characterized by gas chromatography-mass spectrometry (GC-MS). Thirty adult Wistar rats were randomly arranged into six groups (A, B, C, D, E and F) and treated under certain conditions. Haematological analyses were performed according to standard procedures. Saponins, alkaloids, terpenoids, flavonoids and glycosides were present. Oil constituents like octadecanoic acid (stearic acid) (35.30%), a saturated fatty acid was among the components detected in the isolated brown oil. There was a significant decrease (p < 0.05) in the levels of white blood cells (WBC) among the experimental groups (D and E), while mean corpsular haemoglobin (MCH) increased significantly (p < 0.05) with experimental group E (receiving high dose of the extract). This study indicated that methanol extract of A. precatorius can offer protection against blockage or plaques caused by high lipid diet. Keywords: Abrus precatorius, phytochemicals, histology, haematology

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Chopra, Vijay, Aishwarya Shriwastva, Gopal L. Khatik, Manish Vyas, Pramod Yadav, P. K. Prajapati, and Bhupendra Tomar. "A Comprehensive Review on Pharmacological Properties of Abrus precatorius L." Natural Products Journal 10, no. 5 (September 11, 2020): 543–49. http://dx.doi.org/10.2174/2210315509666190801104010.

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Background: Abrus precatorius L. (A. precatorius) is a valuable plant from the family Fabaceae which is a pea family. It is commonly known as Gunja or Jequirity, significantly found throughout India mainly Himalaya to Southern India and Ceylon. It is considered a poisonous plant due to the presence of abrin. Objective: A. precatorius has many pharmacological and biologically active constituents, such as alkaloids, glycosides and flavonoids situated in different parts of the plant. The objective of this review is to provide a retrospective study based on its anticancer potential. Results: Recent studies of A. precatorius are based on the isolation, characterization, and pharmacological evaluation of different secondary metabolites. These constituents possess significant cytotoxic properties against various cancer cell lines including breast, lung, liver, ovarian, prostate and leukaemia. A. precatorius is also reported to have anti-diabetic, anti-microbial, abortifacient, antioxidant, anthelmintic activity, antifertility, nephroprotective, and immunomodulatory activities. Conclusion: The present review summarizes the anticancer potential of A. precatorius and its constituents. However, extensive research is required to establish it as a potent chemotherapeutic agent.

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Pramiastuti, Oktariani, Desi Sri Rejeki, and Siti Lailatul Karimah. "AKTIVITAS ANTIBAKTERI PASTA GIGI EKSTRAK DAUN SAGA (Abrus precatorius Linn.) PADA Sterptococcus mutans." Bhamada: Jurnal Ilmu dan Teknologi Kesehatan (E-Journal) 11, no. 1 (March 13, 2020): 10. http://dx.doi.org/10.36308/jik.v11i1.207.

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Daun saga (Abrus precatorius Linn.) telah diketahui mengandung senyawa metabolit skunder berupa alkaloid, flavonoid dan saponin yang memiliki potensi sebagai antibakteri Streptococcus mutans. Penelitian ini bertujuan untuk mengetahui formulasi pasta gigi ekstrak daun saga (Abrus precatorius Linn.) yang memenuhi syarat sediaan yang paling baik dan mengetahui apakah formulasi sediaan pasta gigi ekstrak daun saga (Abrus precatorius Linn.) memiliki aktivitas sebagai antibakteri pada mulut. Ekstraksi yang dilakukan dengan cara remaserasi menggunakan pelarut metanol. Penelitian ini menggunakan 4 formulasi, F1 ekstrak konsentrasi 10%, F2 ekstrak konsentrasi 20%, F3 ekstrak dengan konsentrasi 30% dan F4 yaitu basis pasta (tanpa penambahan ekstrak) yang digunakan sebagai kontrol negatif. Sifat fisik yang diujikan meliputi: uji organoleptik, uji homogenitas dan uji pH. Hasil formulasi pasta gigi ekstrak daun saga berpengaruh terhadap sifat fisik warna dan pH, namun tidak berpengaruh terhadap bau, rasa, bentuk dan homogenitas. Pasta gigi ekstrak daun saga (Abrus precatorius Linn.) memiliki aktivitas sebagai antibakteri tertinggi pada konsentrasi ekstrak 30% dengan zona hambat rata-rata 12mm, kemudian 20% dan 10% dengan zona hambat berturut-turut 9,33mm dan 7,08mm. Daya hambat dianalisis menggunakan Kruskall-Wallis diperoleh signifikan sebesar 0,014 < 0,05 yang berarti Ho ditolak atau ada pengaruh yang signifikan dari keempat formulasi terhadap uji antibakteri tersebut. Hasil uji mann-whitney menunjukkan bahwa ada pengaruh yang signifikan antara formulasi I dengan II, formulasi I dengan III, formulasi II dengan formulasi III sehingga ada perbedaan yang bermakna antar kelompok. Pada formulasi I dengan IV, formulasi II dengan VI dan formulasi III dengan IV memiliki aktivitas antibakteri.

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Noor, Fatima, Abdur Rehman, Usman Ali Ashfaq, Muhammad Hamzah Saleem, Mohammad K. Okla, Abdulrahman Al-Hashimi, Hamada AbdElgawad, and Sidra Aslam. "Integrating Network Pharmacology and Molecular Docking Approaches to Decipher the Multi-Target Pharmacological Mechanism of Abrus precatorius L. Acting on Diabetes." Pharmaceuticals 15, no. 4 (March 29, 2022): 414. http://dx.doi.org/10.3390/ph15040414.

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Type 2 diabetes mellitus (T2DM) is a notable health care load that imposes a serious impact on the quality of life of patients. The small amount of reported data and multiple spectra of pathophysiological mechanisms of T2DM make it a challenging task and serious economic burden in health care management. Abrus precatorius L. is a slender, perennial, deciduous, and woody twining plant used in various regions of Asia to treat a variety of ailments, including diabetes mellitus. Various in vitro studies revealed the therapeutic significance of A. precatorius against diabetes. However, the exact molecular mechanism remains unclarified. In the present study, a network pharmacology technique was employed to uncover the active ingredients, their potential targets, and signaling pathways in A. precatorius for the treatment of T2DM. In the framework of this study, we explored the active ingredient–target–pathway network and figured out that abrectorin, abrusin, abrisapogenol J, sophoradiol, cholanoic acid, precatorine, and cycloartenol decisively contributed to the development of T2DM by affecting AKT1, MAPK3, TNFalpha, and MAPK1 genes. Later, molecular docking was employed to validate the successful activity of the active compounds against potential targets. Lastly, we conclude that four highly active constituents, namely, abrusin, abrisapogenol J, precatorine, and cycloartenol, help in improving the body’s sensitivity to insulin and regulate the expression of AKT1, MAPK3, TNFalpha, and MAPK1, which may act as potential therapeutic targets of T2DM. Integrated network pharmacology and docking analysis revealed that A. precatorius exerted a promising preventive effect on T2DM by acting on diabetes-associated signaling pathways. This provides a basis to understand the mechanism of the anti-diabetes activity of A. precatorius.

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Garaniya, N. H., A. H. Bapodra, and K. D. Ladva. "Phytopharmacological Study of Red, White and Black Variety of Abrus precatorius L." International Letters of Natural Sciences 14 (April 2014): 1–11. http://dx.doi.org/10.18052/www.scipress.com/ilns.14.1.

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Abrus precatorius L. is a leguminous plant of family fabaceae. Plant parts are widely used for medicinal purpose in different region of the world. Seed behavior and phytochemical evaluation of different solvent extracts (i.e. Petroleum ether, Ethyl acetate, Methanol & Water) of leaf and seed of red, white and black varieties of Abrus precatorius L. is carried out in the present study. This study indicates presence of different phytoconstituents i.e. alkaloids, steroids, glycosides, proteins, etc. the present study concludes that the plant parts can be used as very good natural remedy to diagnosed variety of dieses.

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Garaniya, N. H., A. H. Bapodra, and K. D. Ladva. "Phytopharmacological Study of Red, White and Black Variety of <i>Abrus precatorius</i> L." International Letters of Natural Sciences 14 (April 29, 2014): 1–11. http://dx.doi.org/10.56431/p-s3u2tc.

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Abrus precatorius L. is a leguminous plant of family fabaceae. Plant parts are widely used for medicinal purpose in different region of the world. Seed behavior and phytochemical evaluation of different solvent extracts (i.e. Petroleum ether, Ethyl acetate, Methanol & Water) of leaf and seed of red, white and black varieties of Abrus precatorius L. is carried out in the present study. This study indicates presence of different phytoconstituents i.e. alkaloids, steroids, glycosides, proteins, etc. the present study concludes that the plant parts can be used as very good natural remedy to diagnosed variety of dieses.

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Xiao, Zhihui, Shuhong Tao, Yaxian Yang, and Yu Zhang. "A New Isoflavan from Abrus precatorius." Chemistry of Natural Compounds 53, no. 2 (March 2017): 257–59. http://dx.doi.org/10.1007/s10600-017-1965-8.

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Hata, Yoshie, Samad Nejad Ebrahimi, Maria De Mieri, Stefanie Zimmermann, Tsholofelo Mokoka, Dashnie Naidoo, Gerda Fouche, et al. "Antitrypanosomal isoflavan quinones from Abrus precatorius." Fitoterapia 93 (March 2014): 81–87. http://dx.doi.org/10.1016/j.fitote.2013.12.015.

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Mohammad Madaki, Fatima, Adamu Yusuf Kabiru, and Olofu Ogbadoyi Emmanuel. "Antioxidant Properties and Effect of Abrus precatorius Leaves Extract on Haematological and Biochemical Parameters in Rats." Iranian Journal of Toxicology 13, no. 2 (May 1, 2019): 13–18. http://dx.doi.org/10.32598/ijt.13.2.586.1.

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Background: Abrus precatorius (A. precatorius) is a herbal remedy commonly used in traditional medicine. We investigated the phytochemical, antioxidant, toxic properties, and safety of A. precatorius leaves in rats. Methods: Phytochemical studies were conducted using standard procedures. The antioxidant properties were studied using the reducing power and 2, 2′- diphenyl-1-picrylhydrazyl (DPPH) scavenging assays. The effect of the extract on biochemical and haematological parameters were evaluated after the oral administration of the extract at daily doses of 200, 400 and 600 mg/kg of the rats’ body weight for 28 days. Results: Saponin was the most abundant (202.25±9.25 mg/100g) while alkaloids (9.69±0.34 mg/100g) were the least phytochemical content of A. precatorius. The extract had an LD50 value of >5000 mg/kg, demonstrating significant reducing power and DPPH scavenging activities (IC50 = 106.22 μg/mL). The extract significantly decreased the serum bilirubin and AST concentrations but increased the total proteins concentration compared with the controls (p<0.05). Urea, creatinine, ALP, ALT, chloride and albumin concentrations in the treated rats were not significantly different from those of the controls (p>0.05). The 600 mg/kg dose significantly increased the Hb, PCV, RBC and MCHC of the treated rats, compared to those of the controls (p<0.05). All doses of the extract tested significantly increased the platelet count but did not alter the counts of MCV, MCH, TWBC, RDW, lymphocyte and neutrophils (p<0.05). Conclusions: This study demonstrated that the A. precatorious leaves possess antioxidant and erythropoietic properties. It was also found to be relatively safe with regards to the liver and kidney integrity at concentrations up to 600 mg/kg body weight of the rats.

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Reddy, S. K., S. Sandhya, K. R. Vinod, B. Asia, and D. Banji. "CYTOMORPHOLOGICAL AND PHYTOCHEMICAL ANALYSIS OF ABRUS PRECATORIUS LINN." INDIAN DRUGS 51, no. 04 (April 28, 2014): 26–35. http://dx.doi.org/10.53879/id.51.04.p0026.

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Abrus precatorius belongs to the family Fabaceae and is a slender woody perennial climber. The genus Abrus is native to India, introduced to warmer regions of the world. It has gained scientific importance as a potential herbal remedy in treatment of chronic nephritis, diabetes, cancer, bacterial infections, convulsions, jaundice, spermatorrhoea and many others. In the present work, the root of the plant was standardized pharmacognostically by subjecting it to various evaluation parameters like microscopical, physicochemical and phytochemical evaluations. The TS and LS of the root showed prominent xylem vessels and fibres. The powdered microscopy showed the presence of pitted and scalariform xylem vessels. Chemo-microscopical studies using various staining reagents like phloroglucinol and HCl, Schules reagent, Toluidine blue, Safranin, and Sudan III were performed. The chemo-microscopical studies revealed the presence of lignin in the cell walls of xylem, starch grains in the medullary rays etc. In physicochemical evaluation, the ash values and extractive values were studied. Fluorescence analysis performed showed a wide range of fluorescence colours for the powder as well as the extracts. The powdered root was extracted with petroleum ether, benzene, chloroform, ethyl acetate, methanol, alcohol and water. The extracts obtained were concentrated and subjected to chemical tests. From the preliminary chemical tests, presence of flavonoids, tannins and phenolic compounds and saponins was observed. Variety of the compounds present in the root were detected in methanolic extract. These evaluation parameters performed will help in setting a suitable monograph for the plant, as A. precatorious root is an important medicinal herb in the alternative systems of medicine.

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Hassan, Md Abul, M. Oliur Rahman, and Sumona Afroz. "A New Variety of Abrus Precatorius L. (Fabaceae) From Bangladesh." Bangladesh Journal of Plant Taxonomy 28, no. 2 (December 26, 2021): 289–94. http://dx.doi.org/10.3329/bjpt.v28i2.57127.

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A new variety Abrus precatorius L. var. albo-spermum Hassan, Rahman et Afroz, var. nov. is described and illustrated from Bangladesh. The new variety is closest to Abrus preactorius L., but differs by its white coloured oval shaped seeds, short gynoecium which is half the length of longer filaments and with a short style. Bangladesh J. Plant Taxon. 28(2): 289-294, 2021 (December)

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Poudel, Sunita, and Mukesh Kumar Chettri. "Identification of Suitable Plant Species for Vegetation Restoration at Manthali, Nepal." Amrit Research Journal 2, no. 01 (November 17, 2021): 1–10. http://dx.doi.org/10.3126/arj.v2i01.39881.

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The present study aims to find out the suitable native plant species for restoring degraded land in the mountain from 450 m asl to 819 m asl in Khurkot of Manthali. Altogether thirty quadrats were laid to observe frequency, density and coverage of plant species present there, and ultimately, IVI was calculated. Eight plant species – 3 trees like Acacia catechu, Aegle marmelos and Annona squamosa; 3 shrubs like Rhus parviflora, Cipadessa baccifera and Abrus precatorius (woody climber), and 2 herbs like Uraria lagopodiodes and Polypogon monospeliensis were considered for the detailed study based on their high IVI values. Altogether fourteen traits (growth form, life-span, phenology, Raunkiaer’s life-form, canopy height, stem density, mean ramet distance, leaf size, specific leaf area, leaf thickness, seed mass, propagules mass, seed shape and nitrogen fixation) were studied in those eight species. Based on these traits, through this protocol, the plants were again categorized into five syndromes, i.e., establishment syndrome, dispersal syndrome, biomass producing syndrome, persistence syndrome and effect on environment syndrome. From this study, Annona squamosa and Abrus precatorius can be suggested as candidate species for early succession. Similarly, Aegle marmelos, Acacia catechu, Annona squamosa, Rhus parviflora and Abrus precatorius can be recommended to plant for restoration of degraded bushy lands, which are in the phase of secondary succession.

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Laskar, Subrata, Omar Espino, and Debasish Bandyopadhyay. "Isolation, Solid-state Structure Determination, In Silico and In Vitro Anticancer Evaluation of an Indole Amino Acid Alkaloid L-Abrine." Current Cancer Drug Targets 19, no. 9 (December 20, 2019): 707–15. http://dx.doi.org/10.2174/1568009619666190111111937.

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Background: Abrus precatorius Linn. (Kunch in Bengali) is widely spread in tropical and sub-tropical regions. It is a typical plant species which is well-known simultaneously as folk medicine and for its toxicity. Objective: Phytoceutical investigation of the white variety seeds of Abrus precatorius Linn. Methods: Traditional extraction, separation, isolation, and purification processes were followed. The structure was elucidated by various spectral analyses and the solid-state structure of this indolealkaloid was determined by X-ray crystallographic analysis. Docking interactions of L-abrine had been studied against ten major proteins, responsible for various types of cancers. In silico studies were done by Schrödinger Maestro, AutoDock4, PyMOL and AutoDock Vina. The protein structures were downloaded from Protein Data Bank. Sulforhodamine B (SRB) colorimetric assay was used for in vitro anticancer evaluation against four human cancer cell lines. Results: An indole-containing unusual amino acid alkaloid had been isolated from the white variety seeds of Abrus precatorius Linn. In silico docking studies demonstrated significant antiproliferative activity against four human cancer cell lines. Conclusion: The solid-state zwitterion structure of the indole-containing alkaloid (α-methylamino- β-indolepropionic acid, L-abrine) has been confirmed for the first time by X-ray crystallography. Highly promising in silico and in vitro results indicate that L-abrine may find its space in future anticancer drug discovery research.

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Fernando, C. "Poisoning due to Abrus precatorius (jequirity bean)." Anaesthesia 56, no. 12 (December 2001): 1178–80. http://dx.doi.org/10.1111/j.1365-2044.2001.02316.x.

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Fernando, C. "Poisoning due to Abrus precatorius (jequirity bean)." Anaesthesia 56, no. 12 (December 2001): 1178–80. http://dx.doi.org/10.1046/j.1365-2044.2001.02316.x.

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Xiao, Zhihui, Fazuo Wang, Hao Yin, Aijun Sun, Chuanrong Li, Qingxin Li, and Si Zhang. "A new flavanone glucoside from Abrus precatorius." Chemistry of Natural Compounds 48, no. 4 (September 2012): 565–67. http://dx.doi.org/10.1007/s10600-012-0311-4.

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Sarkar, Sumantra, Kaushambi Basu, Jayati Das, and Supratim Datta. "Abrus precatorius poisoning and central pontine myelinolysis." Journal of Pediatric Neurosciences 12, no. 4 (2017): 353. http://dx.doi.org/10.4103/jpn.jpn_84_17.

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Jang, David H., Robert S. Hoffman, and Lewis S. Nelson. "Attempted Suicide, by Mail Order: Abrus precatorius." Journal of Medical Toxicology 6, no. 4 (June 19, 2010): 427–30. http://dx.doi.org/10.1007/s13181-010-0099-1.

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Izebe, S. Kasim, Y. K. E. Ibrahim, J. A. Onoalapo, K. Ibrahim, P. Oladosu, N. Nneka Ibekwe, and P. Obi Adigwe. "Synergistic activity of Tetrapleura tetraptera and Abrus precatorius fractions extract against Streptococcus pneumoniae and Mycobacterium tuberculosis." Journal of Phytomedicine and Therapeutics 22, no. 1 (June 28, 2023): 1045–57. http://dx.doi.org/10.4314/jopat.v22i1.3.

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Streptococcus pneumonia and Mycobacterium tuberculosis and both account for high morbidity and mortality globally. This study is aimed to determine the antimicrobial and synergistic activity of Tetrapleura tetraptera and Abrus precatorius against these two respiratory infections. The leaves of T. tetraptera and A. precatorius were extracted using 70% methanol and further fractionations of the further fractionation. The crude and fractions were screened for antimicrobial activity on Streptococcus pneumonia and Mycobacterium tuberculosis using micro-dilution technique. The synergistic activity of fractions of T. tetraptera and A. precatorius was analyzed using standard checkerboard. The phytochemical composition of the fractions was analyzed using standard technique. The crude extracts of T. tetraptera and A. precatorius had activity against S. pneumoniae and M. tuberculosis at varied concentrations of 0.7 to 6.9 mg/l. The fractions alone of T. tetraptera and A. precatorius had activity at lower concentrations ranging 0.03 to 0.98 mg/ml against test bacteria. The combined fractions T. tetraptera and A. precatorius against S. pneumoniae and M. tuberculosis provided better activity at concentrations of 0.01 to 0.33 mg/ml to give synergy and indifference activity. The phytochemicals identified in A. precatorius and T. tetraptera included tannins, saponins, flavonoids, phenols and resins but differ in alkaloids detected in only T. tetraptera. This study has shown that A. precatorius and T. tetraptera possess antimicrobial activity against Streptococcus pneumonia and Mycobacterium tuberculosis. The combined fractions of T. tetraptera and A. precatorius showed greater antimicrobial activity than when each plant is used individually. The synergistic effect of these fractions of T. tetraptera and A. precatorius can be used in the development of phyto-medicine that will be efficacious, increase cure rate and decrease resistance in S. pneumoniae and M. tuberculosis.

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Alves de Souza, Paulo Adller, Glenda Kely De Araújo Santana, Wandson Maranhão Façanha, Yohav Yashin Nazario dos Santos, and Breno Marques da Silva e Silva. "Morfo-Anatomia do Fruto, da Semente e Plântula de Abrus precatorius L. (Fabaceae)." Ensaios e Ciência C Biológicas Agrárias e da Saúde 25, no. 4 (December 14, 2021): 462–67. http://dx.doi.org/10.17921/1415-6938.2021v25n4p462-467.

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Abrus precatarius L., conhecida popularmente por “tento”, pertencente à família Fabaceae, possui sementes ornamentais amplamente usadas na confecção de biojóias. Para a identificação e avaliação em tecnologia de sementes, as informações sobre a morfologia de frutos, sementes e plântulas são escassas para esta espécie. Desta forma, o objetivo do presente trabalho foi descrever morfo-anatomicamente o fruto, a semente e a plântula de A. precatorius. Para a descrição morfo-anatômica, os frutos, as sementes e as plântulas foram avaliados por meio de microscopia estereoscópica e eletrônica de varredura. Segundo as análises, as maiores frequências para o comprimento, largura, espessura, peso e número de sementes/fruto em A. precatorius. foram entre 1,68 a 2,15cm, 0,71 a 1,30cm, 0,38 a 0,76cm, 0,085 a 0,106g e 3 a 5 sementes/fruto, respectivamente. O fruto de A. precatorius é do tipo legume, seco, deiscente (valvas contorcidas), constricto, pseudo-septado, achatado dorso-ventralmente e oblongo-elíptico,com base obtusa e ápice cuspidado e com placentação lateral ou pariental. As sementes são exalbuminosas, estenospérmicas, subglobosas, bicolores. As plântulas possuem folhas compostas, alternas, e a germinação é epigea-fanerocotiledonar. Neste estudo, foi possível descrever detalhes dos frutos, sementes e plântulas de A. precatorius que irão compor dados sobre a ecologia e sistemática vegetal da espécie. Palavras-chave: Morfologia. Desenvolvimento Pós-Seminal. Germinação. Fabaceae. Abstract Abrus precatorius L., known as tento, belongs to the family Fabaceae, possess seeds used to make handicrafts. For the forest identification and seeds technology, the information on the biology and therefore for the production of his fruits, seeds and seedlings are incipient. Thus, the aim of this study was the morpho-anatomical description of fruits, seeds and seedling of A. precatorius. For the morpho-anatomical description, the evaluations were examined by optical and scanning electron microscopy. According to the analyzes, the highest frequenciesforlength, width, thickness, weight and number of seedsA. precatorius. fruit were between 1,68 a 2,15cm, 0,71 a 1,30cm, 0,38 a 0,76cm, 0,085 a 0,106g e 3 a 5 seeds/fruit, respectively. The fruit is dehiscent legume, constrict, pseudo-septate, flattened dorsoventrally, oblong-ellipticall, with cuspidate base and apex, and lateral placentation. The seeds are exalbuminous, setenospermic, subglobous and bicolours. The seedlings have compound leaves, and their germination is phanero-epigeal.In this study, it was possible to describe details of the fruits, seeds and seedlings of A. precatorius that will compose data on the ecology and plant systematics of the species. Keywords: Morphology. Post-Seminal Development. Germination. Fabaceae.

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Rambe, Robiatun, Ratih Paramitha, Ernawaty Ginting, and Mita Yusmira Lestari Caniago. "Uji Efektivitas Sediaan Salep Ekstrak Daun Saga (Abrus precatorius Linn) Untuk Pengobatan Luka Pada Kelinci (Oryctolagus cuniculus)." Journal of Pharmaceutical And Sciences 4, no. 2 (December 31, 2021): 111–16. http://dx.doi.org/10.36490/journal-jps.com.v5i1.56.

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Daun saga (abrus precatorius Linn) memiliki kandungan flavonoid, tanin, triterpenoid yang mampu memberikan efek antibakteri.Penelitian ini bertujuan untuk membuat salep dari ekstrak daun saga (abrus precatorius Linn) dan uji efektivitas sediaan salep terhadap pengobatan luka pada kulit kelinci. Pembuatan salep ekstrak daun saga yang telah memenuhi syarat dan diujikan pada hewan uji kelinci sebanyak 5 ekor dengan perlakuan, dasar salep berlemak (kontrol negatif), gentamicin salep (kontrol positif), ekstrak daun saga 10%, 20% dan 30%. Semua kelinci disayat sepanjang 1,5cm dan diberikan sediaan salep ekstrak daun saga sebanyak 0,2 mL. Luka diolesi tiga kali sehari dengan salep yang diuji.Pengamatan luka dilakukan setiap hari selama 8 hari.Hasil penelitian menunjukkan formulasi salep ekstrak daun saga memenuhi persyaratan uji salep menurut Farmakope Indonesia edisi III.Luka sayat yang dioleskan salep ekstrak daun saga mengalami penyempitan luka, membentuk keropeng dan menutup luka mulai hari ke 3.

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Bhattacharjee, SC, MM Matin, and M. Nasiruddin. "Insecticidal effects of two medicinal plants Polygonum hydropiper L. and Abrus precatorius L. leaves against the rice weevil Sitophilus oryzae L. (Coleoptera: Curculionidae)." Journal of Biodiversity Conservation and Bioresource Management 5, no. 2 (January 15, 2020): 107–14. http://dx.doi.org/10.3329/jbcbm.v5i2.44921.

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During the study, the leaves of two medicinal plants, Polygonum hydropiper and Abrus precatorius were extracted with water, ethanol, methanol and petroleum ether solvents and tested against the rice weevil S. oryzae L. for insecticidal properties. Response varied with plant species. The mortality of adults increased with increasing dose concentrations from 1000 ppm to 5000 ppm each solution, with an exposure time of 72 hours. LC50 values calculated were found to be 15091.436 ppm with water, 5051.534 ppm with ethanol, 5111.063 ppm with methanol and 4305.348 ppm with petroleum ether extracts of P. hydropiper and 9687.292 ppm with water, 6263.849 ppm with ethanol, 4682.683 ppm with methanol and 3222.984 ppm with petroleum ether extracts of Abrus precatorius leaves corresponding their concentrations of the leaf extract solutions at 1000ppm, 2000 ppm, 3000 ppm, 4000 ppm and 5000 ppm respectively. The results of the study showed that methanol and petroleum ether extrcts of P. hydropiper and ethanol, methanol and petroleum ether extracts of A. precatorius showed good toxicity. It appeared that the leaf extracts had some insecticidal activities against S. oryzae adult. J. Biodivers. Conserv. Bioresour. Manag. 2019, 5(2): 107-114

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Shrestha, Ninadini, B. Karki, S. Regmi, PS Shrestha, SP Acharya, and R. Pathak. "Abrus Precatorius Toxicity Presenting with Diarrhoea and Encephalopathy: A Case Report." Nepal Medical College Journal 22, no. 3 (November 2, 2020): 189–92. http://dx.doi.org/10.3126/nmcj.v22i3.32657.

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Infective etiologies are the first differentials that come to the mind in clinical conditions presenting with diarrhea associated with encephalopathy. We report a case of a 21 year old lady diagnosed as acute infective gastroenteritis and treated for the same only to manifest itself later as encephalopathy leading to a diagnostic dilemma. The clinical manifestations had started from abdominal cramps, bloody diarrhea followed by altered sensorium. A detailed history later revealed the use of the roots of Abrus precatorius for the treatment of sub-fertility was the missing piece of the diagnostic puzzle. Only after confirmation of the herb did the temporal sequence of events seemed logical. The patient was successfully managed for toxic acute disseminated encephalomyelitis (ADEM). Abrus precatorius is a commonly used herb used in traditional medicinal practice in many cultures. Various aspects of its toxicity can mimic other more commonly encountered medical ailments.

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Misrahanum, Misrahanum, Cut Intan Annisa Puteri, and Cut Yulvizar. "ACTIVITY TEST OF Abrus precatorius L. LEAF EXTRACT AGAINST CLINICAL Streptococcus pneumonia GROWTH*." Jurnal Natural 17, no. 1 (March 31, 2017): 58. http://dx.doi.org/10.24815/jn.v17i1.7260.

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Abstract. Saga (Abrus precatorius L.) have been used by Indonesian community as a traditional medicine. The research aims to determine the activity of the methanol extract of saga leaves to inhibit the growth of clinical Streptococcus pneumoniae growth. Inhibition tests was done with casting cup method. The results showed that the methanol extract of saga leaves at a concentration of 37,5; 50; 62,5; 75 and 87,5 mg/mL formed growth inhibition zone of clinical S. pneumoniae with consecutive average of 0,5; 1,75; 2,82; 4,00; and 4,82 mm. Based on the results of the research can be concluded that the methanol extract of saga leaves had activity in inhibiting the growth of clinical S. pneumoniae isolates with low category. Key words: Abrus precatorius L., Clinical Streptococcus pneumoniae, Methanol extract*Judul ini telah dipresentasikan pada Seminar Nasional: Indonesian Students Conference on Science and Mathematics(ISCSM) 11-12 November 2015, Banda Aceh Indonesia

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S. Nassir, Zahra'a, and Enas J. Khadem. "phytochemical investigations of Iraqi Abrus precatorius Linn. plant." Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512) 27, no. 1 (June 3, 2018): 30–38. http://dx.doi.org/10.31351/vol27iss1pp30-38.

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The plant Abrus precatorius, which belong to Leguminosae (Fabaceae) family and known as Crab’s eyes, Rosary pea with characteristic red and black seeds. It was used in folk medicine in India, China and East Asian countries for treatment of various diseases. The plant was extracted by '' general method of extraction'' (Harborne, 1973) using 80% aqueous ethanol as a solvent of extraction by soxhlet apparatus. Preliminary qualitative phytochemical screening were performed on the crude ethanolic extract and revealed the presence of alkaloids, flavonoids ,terpenoids and phytosterols in Iraqi Abrus precatorius plant. Three different fractions were obtained from crude extract which are fraction one (chloroform fraction), fraction two (ethyl acetate fraction), and fraction three (petroleum ether fraction) which are represent alkaloids, flavonoids and steroids respectively. The alkaloid abrine was isolated from the chloroform fraction in pure form by using preparative thin layer chromatography (PTLC) and then subjected to different physico-chemical and specteral analytical techniques to identify its chemical structure: melting point (M.P.), thin layer chromatography (TLC), high performance liquid chromatography (HPLC) , fourier transforms infrared spectra (FT-IR) and elemental microanalysis (CHNO).

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Kumar, Praveen, Manish Rajak, and Jai Kumar Singh. "A REVIEW ON TOXICITY OF GUNJA (ABRUS PRECATORIUS)." International Ayurvedic Medical Journal 9, no. 7 (July 15, 2021): 1469–73. http://dx.doi.org/10.46607/iamj2309072021.

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Gunja (Abrus precatorius Linn.) is a toxic plant which is described in various Samhita and other Ayurvedic texts. In Sushruta Samhita Vishaja dravyas are classified into Sthavara, Jangama and Kritima Visha. Gunja is mentioned in Sthavara Visha. In Sthavara Visha it is mentioned under Moolaja Adhisthan, which is one of the ten Adhisthan of Sthavara Visha. According to Rasa Tarangani Sthavara Visha are further divided into Mahavisha and Upavisha. Gunja is mentioned in Upavisha which is less potent toxic than Mahavisha. All parts of the plant are toxic, but the most toxic part is the seed which contains the active principle abrin. According to the modern concept, it is an irritant organic poison. In the Ayurvedic concept, if toxic plants are used after Shodhana process, they are useful in various types of diseases. The main aim of this study is to collect all the information related to Gunja and its toxicity. Keywords: Gunja, Visha, Toxicity, Abrin, Shodhana

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Xiao, Zhi-Hui, Fa-Zuo Wang, Ai-Jun Sun, Chuan-Rong Li, Cai-Guo Huang, and Si Zhang. "A New Triterpenoid Saponin from Abrus precatorius Linn." Molecules 17, no. 1 (December 30, 2011): 295–302. http://dx.doi.org/10.3390/molecules17010295.

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Kim, Nam-Cheol, Darrick Kim, and A. Douglas Kinghorn. "New Triterpenoids from the Leaves of Abrus Precatorius." Natural Product Letters 16, no. 4 (January 1, 2002): 261–66. http://dx.doi.org/10.1080/10575630290020596.

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Yonemoto, Ryuta, Miyuki Shimada, Maria D. P. T. Gunawan-Puteri, Eisuke Kato, and Jun Kawabata. "α-Amylase Inhibitory Triterpene from Abrus precatorius Leaves." Journal of Agricultural and Food Chemistry 62, no. 33 (August 8, 2014): 8411–14. http://dx.doi.org/10.1021/jf502667z.

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Hata, Yoshie, Melanie Raith, Samad Ebrahimi, Stefanie Zimmermann, Tsholofelo Mokoka, Dashnie Naidoo, Gerda Fouche, et al. "Antiprotozoal Isoflavan Quinones from Abrus precatorius ssp. africanus." Planta Medica 79, no. 06 (March 19, 2013): 492–98. http://dx.doi.org/10.1055/s-0032-1328298.

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Nwodo, O. F. C., and E. O. Alumanah. "studies on Abrus precatorius seeds. II: Antidiarrhoeal activity." Journal of Ethnopharmacology 31, no. 3 (March 1991): 395–98. http://dx.doi.org/10.1016/0378-8741(91)90024-8.

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Banger, Swati, Rita Singh, Nagesh Tripathi, Vijai Pal, and Ajay Kumar Goel. "One step Purification and Characterisation of Abrin Toxin from Abrus Precatorius Seeds." Defence Life Science Journal 4, no. 4 (October 21, 2019): 231–35. http://dx.doi.org/10.14429/dlsj.4.14967.

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Abrin is a plant toxin obtained from Abrus precatorius seeds. It belongs to the type II ribosomal inactivating proteins (RIPs) consisting of two chains namely, catalytically active A chain and sugar binding B chain linked by a single disulphide bond. Due to high toxicity of abrin, its exposure or consumption can lead to serious public health problems. In the present work, we have extracted and purified the abrin toxin from Abrus precatorius seeds. The toxin was purified using a single step anion exchange chromatography. The purified protein was characterized by SDS-PAGE and MALDI- TOF to confirm its purity. The toxicity of purified abrin toxin was also confirmed by injecting the toxin in mice. The purified protein was further used to raise antibodies in mice and characterized by indirect Enzyme Linked Immunosorbent Assay. The results of present study established the use of single step ion exchange chromatography to purify abrin toxin for further development of its detection system.

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Das, Shonkor, and Sonali Bhakta. "The medicinal values of Abrus precatorius: a review study." Journal of Advanced Biotechnology and Experimental Therapeutics 3, no. 2 (2020): 84. http://dx.doi.org/10.5455/jabet.2020.d111.

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Barve, KalyaniH, and Neha Ojha. "Effective detoxification of Abrus precatorius Linn. seeds by Shodhana." Journal of Ayurveda and Integrative Medicine 4, no. 2 (2013): 82. http://dx.doi.org/10.4103/0975-9476.113875.

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Karthikeyan, Aishwarya, and S. Deepak Amalnath. "Abrus precatorius poisoning: A retrospective study of 112 patients." Indian Journal of Critical Care Medicine 21, no. 4 (2017): 224–25. http://dx.doi.org/10.4103/ijccm.ijccm_320_16.

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Sahni, Vaibhav, Satish K. Agarwal, Narinder P. Singh, and Sunandan Sikdar. "Acute demyelinating encephalitis after jequirity pea ingestion (Abrus precatorius)." Clinical Toxicology 45, no. 1 (January 2007): 77–79. http://dx.doi.org/10.1080/15563650601006116.

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Saxena, V. K., and D. N. Sharma. "A new isoflavone from the roots of Abrus precatorius." Fitoterapia 70, no. 3 (June 1999): 328–29. http://dx.doi.org/10.1016/s0367-326x(99)00036-2.

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Kimura, Yoshinobu, Sumihiro Hase, Tokuji Ikenaka, and Gunki Funatsu. "Structural analyses of sugar chains from Abrus precatorius agglutinin." Biochimica et Biophysica Acta (BBA) - General Subjects 966, no. 1 (July 1988): 160–67. http://dx.doi.org/10.1016/0304-4165(88)90139-0.

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Dhanti, Kurnia Ritma. "Skrining antikanker menggunakan metode BST (Brine Shrimp Lethality Test) pada ekstrak metanol daun saga (Abrus precatorius L.) dengan partisi etanol." Riset Informasi Kesehatan 7, no. 1 (June 30, 2018): 61. http://dx.doi.org/10.30644/rik.v7i1.129.

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Latar belakang : Pengembangan senyawa antikanker dari bahan alami perlu dilakukan untuk meminimalisir efek samping dari penanganan penyakit kanker yang saat ini banyak dilakukan. Suatu senyawa dapat diketahui potensi antikankernya dengan pendekatan menggunakan metode BST (Brine Shrimp Lethality Test). Ekstrak metanol daun saga (Abrus precatorius L.) bersifat toksik terhadap larva A. salina Leach. Tujuan : Mengetahui bagian teraktif dari ekstrak metanol daun saga yang dipartisi (dipisahkan) menggunakan pelarut etanol. Metode : Ekstrak metanol daun saga dipartisi dengan pelarut etanol hingga terbentuk bagian larut dan tidak larut. Kedua bagian tersebut diuji menggunakan metode BST dengan 5 kali ulangan dan 3 replikasi yang masing-masing menggunakan 10 ekor larva A.salina. Hasil : Dari perhitungan didapatkan nilai LC50 bagian larut etanol sebesar 144,544 ppm sedangkan nilai LC50 bagian tidak larut etanol sebesar 151,356 ppm. Kesimpulan : Bagian larut etanol menyebabkan persentase kematian yang lebih tinggi daripada bagian tidak larut. Nilai LC50 bagian larut etanol lebih rendah dibanding bagian tidak larutnya. Semakin rendah nilai LC50 senyawa, maka semakin berpotensi pula untuk dikembangkan sebagai agen antikanker. Kata kunci : toksisitas, Abrus precatorius L., Artemia salina Leach., antikanker, partisi.

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Widianto, Eri, Dian Budhi Santoso, Kardiman Kardiman, and Asep Erik Nugraha. "Pemberdayaan Masyarakat tentang Pemanfaatan Tanaman Saga (Abrus Precatorius L) di Desa Tanahbaru Pakisjaya Karawang." Aksiologiya: Jurnal Pengabdian Kepada Masyarakat 4, no. 1 (December 10, 2019): 63. http://dx.doi.org/10.30651/aks.v4i1.2294.

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ABSTRAKTanaman obat saat ini banyak digunakan baik sebagai obat dan perawatan kesehatan. Tanaman obat menjadi sumber bahan baku penting yang sebelumnya belum diketahui kandungan kimianya. Tanaman Saga (Abrus Precatorius L) banyak ditemukan di Indonesia seperti di Desa Tanahbaru, Pakisjaya, Karawang. Tanaman Saga banyak mengandung flavonoid, terpenoid, tanin, alkaloid dan saponin. Tanamn Saga dapat digunakan sebagai antiseptik, anti virus, anti malaria dan anti fertilitas. Pada kegiatan ini bertujuan untuk pemberdayaan masyarakat Desa Tanahbaru tentang pemanfaatan tanaman Saga. Kegiatan ini dilakukan dengan evaluasi kegiatan awal, sosialisasi, pendampingan dan evaluasi akhir kegiatan.Kata Kunci: pemberdayaan; tanaman Saga; tanaman obat. ABSTRACT Medicinal plants are being used as a drug and health care delivery system. Medicinal plants can be important source of previously unknown chemical substances. Saga (Abrus Precatorius L) abundantly found in Indonesia such as in Tanahbaru village, Pakisjaya, Karawang. Saga principally contains falvonoids, terpenoid, tanin, alkaloids dan saponin. It have been for antiseptic, anti-viral, anti-malarial, and antifertility. This activity aims to community empowerment in Tanahbaru village about Saga plants. Activities are conducted by initial evaluation of activities, socialization, assistance and final evaluation activities.Keywords: empowerment; medicinal plants; Saga plants.

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Journal articles on the topic 'Abrus precatorius'

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