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1

T G, Nagaraja. "EVALUATION OF ANTI-MYCOTIC ACTIVITY OF ACACIA CATECHU WILLD. (MIMOSACEAE)." Journal of Biopesticides 01, no. 02 (2008): 197–98. http://dx.doi.org/10.57182/jbiopestic.1.2.197-198.

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ABSTRACT An attempt was made to assess the antimycotic activity of Acacia catechu Willd. extracts using three different solvents such as ethanol, acetone and hexane. Agar well diffusion technique was followed for screening against chosen fungi like Aspergillus niger, Fusarium oxysporum, Alternaria alternata, Rhizopus stolonifer and Macrophoma phaseolina. The maximum inhibition was recorded in ethanol, acetone and hexane roots extracts. A. niger growth was controlled by acetone extract of bark, where as F. oxysporum, A. alternata, R. stolonifer and M. phaseolina by acetone extracts of A. catechu extract. These extracts can be utilized for the management of this plant. It is recommended to isolate, identify and integrate the bioactive principle in these pathogens management.
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2

R Kusugal, Dr Jyotsna, Dr Swati Setty, Dr Pradeep Agnihotri, and Dr Srinath Thakur. "Evaluation of antimicrobial properties of acacia catechu (Khadir): an in-vitro studyEvaluation of antimicrobial properties of acacia catechu (Khadir): an in-vitro study." RGUHS Journal of Dental Sciences 12, no. 2 (2020): 25–30. http://dx.doi.org/10.26715/rjds.12_2_6.

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Context: Acacia catechu has got antimicrobial property. The evaluation of this property against periodontal pathogens may open new doors to treatment modalities of gingivitis and periodontitis. Aims: To evaluate the antimicrobial property of Acacia catechu (Khadir) against periodontal pathogens, Porphyromonas gingivalis (Pg) and Aggregatibacter actinomycetemcomitans (Aa) in subgingival plaque samples of generalized periodontitis patients. Settings and Design: Prospective, observational, microbiological, in-vitro. Methods and Material: Subgingival plaque samples of generalized periodontitis patients were collected and the two pathogens were isolated and cultured. Herbal extract was prepared in accordance with principles of Ayurveda. Antimicrobial activity was determined by minimal inhibitory concentration (MIC) and time kill assay. Statistical analysis used: None. Results: The water extract of Acacia catechu showed antibacterial property at 100μg/ml dilution in four samples for Pg and at 0.2μg/ml dilution in one sample. Antibacterial property was noted at 0.4μg/ml dilution in four samples for Aa by MIC. Bacteriostatic effect against Pg and Aa was observed by time kill assay. Conclusions: Acacia catechu bark extract exhibited antimicrobial activity against Pg and Aa. The extract also exhibited bacteriostatic effect against Pg and Aa till two hour.
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3

Archana, Tiwari, and Tiwari Avinash. "Comparative study of qualitative flavonoid content of Acacia catechu bark extracts." World Journal of Biology Pharmacy and Health Sciences 16, no. 2 (2024): 181–88. https://doi.org/10.5281/zenodo.10792459.

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Plants include a family of secondary metabolites called flavonoids, which are often included in human diets. Many of these bases have been shown to have positive medicinal potential. The purpose of this investigation was to determine if flavonoids were present in various test extracts from test plant samples. Thirty separate samples of&nbsp;<em>Acacia catechu</em> bark were gathered for this study from various seasonal circumstances in the research location. Six extracts were then prepared from each sample. The presence or absence of flavonoids in these extracts was then examined using various techniques. The test sample extracts in ethanol, methanol, aqueous, acetone, and chloroform were found to contain flavonoids, however the benzene extracts were found to be free of the same. Based on the dark-colored reaction mixture, it was claimed that the flavonoids content of both alcoholic extracts was relatively higher. This exploratory study could provide the foundation for future investigations into the therapeutic uses of native plants.
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4

Trishala, A., T. Lakshmi, S. Rajeshkumar, Deepa Gurunathan, RV Geetha, and Anitha Roy. "Physicochemical Profile of Acacia Catechu Bark Extract-An Invitro Study." Indian Journal of Public Health Research & Development 10, no. 11 (2019): 3513. http://dx.doi.org/10.5958/0976-5506.2019.04129.9.

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5

Puttachar, Srikrishna Lingadahalli. "Extraction and Standardization of BioJoin Trademark Product for Joint Health and Muscle Strength." International Journal for Research in Applied Science and Engineering Technology 13, no. 1 (2025): 633–39. https://doi.org/10.22214/ijraset.2025.66358.

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Boswellic acids are naturally present in gum extrudes of Boswellia serrate tree. Boswellic acids has promising activity on joint pain and muscle strength. The study aims at developing a more potential product “BioJoin™”, combining Boswellia serrata and Acacia catechu, which provides bone health, immunity support, enhanced mobility and promote joint health and pain relief. Boswellic acid, Catechins, Polyphenols enhanced with required minerals were combined to increase the efficacy of the product and designed into powder form and tablet form for consumption. The Acacia catechu extract was tested with HPLC for the catechin content and found to be not less than 40% and boswellic acid in Boswellia serrata extract was found to be not less than 65% by HPLC. Final Biojoin product was tested for total polyphenol content and was found to contain not less than 15% polyphenols which could provide benefit to the bone health and strength Bone health is important at every age and stage of life. The skeleton is our body's storage bank for several minerals that are necessary for our bodies to function. If we do not have enough minerals in our diets to keep our bodies functioning, this causes our bones to grow weaker and leads to inflammatory responses. Loss of bone strength can lead to several bone disorders in which bones become very fragile and more likely to break. Polyphenols, a class of natural antioxidants, is found in Acacia catechu which belongs to the Fabaceae family. Catechins in Acacia catechu have shown anti-inflammatory effects by modulating inflammatory pathways. These compounds may inhibit the production of pro-inflammatory cytokines and enzymes such as COX-2 (cyclooxygenase-2), 5-LOX (5-lipoxygenase), and TNF-alpha (tumor necrosis factor-alpha), which play a role in chronic inflammation. As such, Acacia catechu extract can potentially alleviate symptoms in inflammatory conditions like arthritis, rheumatoid arthritis, and gout
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6

Waseem, Uzma, Anoosha Waseem, Nadia Majeed, Fauzia Qureshi, Muhammad Qasim Muneer, and Syeda Rizwana Jafri. "Gastroprotective effects of plants extracts: Acacia catechu on gastric mucosal injury in experimental albino rats model." International Journal of Basic & Clinical Pharmacology 10, no. 4 (2021): 347. http://dx.doi.org/10.18203/2319-2003.ijbcp20211013.

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Background: Around the globe acid peptic disease and its potential complications are among the major cause of morbidity and is a significant burden on health system. Till now the main stay of treatment are the pharmaceutical agents which decrease the secretion of acid. But these have potential complications and tolerability issues. Among such plants one is Acacia catechu commonly available in India and Pakistan.Methods: This experimental study involved 48 albino rats that were divided into four groups. Group A, B, C, and D were given water, 100mg aspirin, 100 mg aspirin+ 250 mg Acacia catechu and 100 mg aspirin+500 mg Aacacia catechu respectively, and were sacrificed on day 3, 7 and 14th day of study and observed for changes.Results: Difference between blood vessels in subgroup B1 and subgroup C1 with subgroup D1 was statistically significant (p=0.05) and (p=0.001). Group C1 and D1 had normal vessels in mucosa and submucosa. However, dilatation of blood vessels was noted in both groups receiving Acacia catechu along with ASA.Conclusions: Aqueous extracts of Acacia catechu stem and bark showed significant anti-ulcer and anti-inflammatory activities by increasing blood flow to the stomach.
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7

Karki, Rajaram, Ajay Kumar Bajgai, Nawaraj Khadka, et al. "Acacia catechu Bark Alkaloids as Novel Green Inhibitors for Mild Steel Corrosion in a One Molar Sulphuric Acid Solution." Electrochem 3, no. 4 (2022): 668–87. http://dx.doi.org/10.3390/electrochem3040044.

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In situ corrosion inhibition in acid cleaning processes by using green inhibitors is at the forefront of corrosion chemistry. Plant extracts, especially alkaloids, are known to be good corrosion inhibitors against mild steel corrosion. In this research, alkaloids extracted from Acacia catechu have been used as green corrosion inhibitors for mild steel corrosion in a 1 M H2SO4 solution. Qualitative chemical tests and FTIR measurements have been performed to confirm the alkaloids in the extract. The inhibition efficiency of the extract has been studied by using weight-loss and potentiodynamic polarization methods. A weight-loss measurement has been adopted for the study of inhibitor’s concentration effect, with a variation employed to measure the inhibition efficiency for time and temperature. The weight-loss measurement revealed a maximum efficiency of 93.96% after 3 h at 28 °C for a 1000 ppm alkaloid solution. The 1000 ppm inhibitor is effective up to a temperature of 48 °C, with 84.39% efficiency. The electrochemical measurement results revealed that the alkaloids act as a mixed type of inhibitor. Inhibition efficiencies of 98.91% and 98.54% in the 1000 ppm inhibitor concentration solution for the as-immersed and immersed conditions, respectively, have been achieved. The adsorption isotherm has indicated the physical adsorption of alkaloids. Further, the spontaneous and endothermic adsorption processes have been indicated by the thermodynamic parameters. The results show that alkaloids extracted from the bark of Acacia catechu can be a promising green inhibitors for mild steel corrosion.
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8

Ezhilarasan, Devaraj, Thangavelu Lakshmi, Rajagopal Vijayaragavan, SukhwinderKaur Bhullar, and Ramasamy Rajendran. "Acacia catechu ethanolic bark extract induces apoptosis in human oral squamous carcinoma cells." Journal of Advanced Pharmaceutical Technology & Research 8, no. 4 (2017): 143. http://dx.doi.org/10.4103/japtr.japtr_73_17.

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9

Shukla, Kavita Varma, and Deepika Kumari. "Formulation Development and Evaluation of Herbal Toothpaste for Treatment of Oral Disease." Journal of Drug Delivery and Therapeutics 9, no. 4-s (2019): 98–104. http://dx.doi.org/10.22270/jddt.v9i4-s.3344.

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Streptococcus mutans is the most common cause of tooth decay. Parabens and other commonly used as anti-Streptococcus agents in toothpaste industry have numerous side effects such as discoloration of teeth. The herbal extract of all three plants gives antimicrobial and anti-inflammatory activity and prevent and reducing the tooth decay, dental caries and given to freshness of mouth. The aim of present work was development and evaluation of herbal antimicrobial toothpaste containing Bark of Acacia nilotica, Acacia catechu and flower buds of syzygium aromaticum as herbal ingredients. Different types of formulations (F1-F6) were formulated using calcium carbonate as abrasive and Glycerine as humectant in varied concentrations. All the formulations were evaluated for various parameters like dryness, color, appearance, consistency, washability, pH, spreadability and foaming power. Polyherbal toothpaste containing hydroalcoholic extract of plants was tested for antimicrobial activity against Staphylococcus aureus and Streptococcus mutans with different concentrations of toothpaste were used (25, 50and 100 mg/ml). Among the tested bacteria used Staphylococcus aureus was found to be most sensitive to the formulated toothpaste as seen by zone of inhibition (19-24 mm) followed by Streptococcus mutans (13-18 mm). The results showed that the formulated polyherbal toothpaste is promising antimicrobial effects against both organisms. It may be safer compared to fully synthetic toothpaste. Further studies are warranted to prove safety and efficacy of the formulated polyherbal toothpaste.&#x0D; Keywords: Streptococcus mutans, Acacia nilotica, Acacia catechu, syzygium aromaticum, polyherbal toothpaste
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10

Archana, Tiwari, and Tiwari Avinash. "Comparative analysis of the carbohydrate and glycoside contents in bark extracts from Acacia catechu." World Journal of Biology Pharmacy and Health Sciences 16, no. 2 (2023): 156–64. https://doi.org/10.5281/zenodo.10792426.

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This study aimed to investigate and contrast the amounts of carbohydrates and glycosides in several&nbsp;<em>Acacia catechu</em> bark extracts. Using samples collected over the course of two consecutive years, if any, the research also looked at how the seasons affected the same in the samples. This included a comparative analysis of six extracts using ethanol, methanol, aqueous solution, acetone, chloroform, and benzene to determine whether or not they contained glycosidic and/or carbohydrate components. The study's findings showed that soluble sugars and glycosidic chemicals were present in the sample regardless of the solvent system or the time of year it was collected. On the other hand, it was observed that all sample extracts were starch-free. The foundation for more research and the physiological effects of the same for the use of native plants for therapeutic reasons may be provided by this preliminary study.
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11

Archana Tiwari and Avinash Tiwari. "Comparative study of qualitative flavonoid content of Acacia catechu bark extracts." World Journal of Biology Pharmacy and Health Sciences 16, no. 2 (2023): 181–88. http://dx.doi.org/10.30574/wjbphs.2023.16.2.0486.

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Plants include a family of secondary metabolites called flavonoids, which are often included in human diets. Many of these bases have been shown to have positive medicinal potential. The purpose of this investigation was to determine if flavonoids were present in various test extracts from test plant samples. Thirty separate samples of Acacia catechu bark were gathered for this study from various seasonal circumstances in the research location. Six extracts were then prepared from each sample. The presence or absence of flavonoids in these extracts was then examined using various techniques. The test sample extracts in ethanol, methanol, aqueous, acetone, and chloroform were found to contain flavonoids, however the benzene extracts were found to be free of the same. Based on the dark-colored reaction mixture, it was claimed that the flavonoids content of both alcoholic extracts was relatively higher. This exploratory study could provide the foundation for future investigations into the therapeutic uses of native plants.
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12

Archana Tiwari and Avinash Tiwari. "Comparative analysis of the carbohydrate and glycoside contents in bark extracts from Acacia catechu." World Journal of Biology Pharmacy and Health Sciences 16, no. 2 (2023): 156–64. http://dx.doi.org/10.30574/wjbphs.2023.16.2.0471.

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This study aimed to investigate and contrast the amounts of carbohydrates and glycosides in several Acacia catechu bark extracts. Using samples collected over the course of two consecutive years, if any, the research also looked at how the seasons affected the same in the samples. This included a comparative analysis of six extracts using ethanol, methanol, aqueous solution, acetone, chloroform, and benzene to determine whether or not they contained glycosidic and/or carbohydrate components. The study's findings showed that soluble sugars and glycosidic chemicals were present in the sample regardless of the solvent system or the time of year it was collected. On the other hand, it was observed that all sample extracts were starch-free. The foundation for more research and the physiological effects of the same for the use of native plants for therapeutic reasons may be provided by this preliminary study.
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13

Elmi, Abdirahman, Rosella Spina, Arnaud Risler, et al. "Evaluation of Antioxidant and Antibacterial Activities, Cytotoxicity of Acacia seyal Del Bark Extracts and Isolated Compounds." Molecules 25, no. 10 (2020): 2392. http://dx.doi.org/10.3390/molecules25102392.

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Water extract of Acacia seyal bark is used traditionally by the population in Djibouti for its anti-infectious activity. The evaluation of in vitro antibacterial, antioxidant activities and cytotoxicity as well as chemical characterization of Acacia seyal bark water and methanolic extracts were presented. The water extract has a toxicity against the MRC-5 cells at 256 μg/mL while the methanolic extract has a weak toxicity at the same concentration. The methanolic extract has a strong antioxidant activity with half maximal inhibitory concentration (IC50) of 150 ± 2.2 μg/mL using 1-diphenyl-2-picrylhydrazyl (DPPH) and IC50 of 27 ± 1.3 μg/mL using 2,2′-azino-bis 3-ethylbenzthiazoline-6-sulphonic acid (ABTS) radical methods. For ferric reducing/antioxidant power (FRAP) assay, the result is 45.74 ± 5.96 μg Vitamin C Equivalent (VCE)/g of dry weight (DW). The precipitation of tannins from methanol crude extract decreases the MIC from 64 µg/mL to 32 µg/mL against Staphylococcus aureus and Corynebacterium urealyticum. However, the antioxidant activity is higher before tannins precipitation than after (IC50 = 150 µg/mL for methanolic crude extract and 250 µg/mL after tannins precipitation determined by DPPH method). By matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) analysis, the results showed that the condensed tannins consist of two types of catechin and gallocatechin-based oligomers. The fractionation led to the identification of three pure compounds: two flavanols catechin and epicatechin; one triterpene as lupeol; and a mixture of three steroids and one fatty acid: campesterol, stigmasterol, clionasterol, and oleamide.
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Yang, Nai-Yen Jack, Krishna Kaphle, Pei-Hwa Wang, De-Shien Jong, Leang-Shin Wu, and Jen-Hsou Lin. "Effects of Aqueous Extracts of "Betel Quid" and Its Constituents on Testosterone Production by Dispersed Mouse Interstitial Cells." American Journal of Chinese Medicine 32, no. 05 (2004): 705–15. http://dx.doi.org/10.1142/s0192415x04002430.

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Betel quid (BQ) is a favorite chewing item among many communities in different parts of Asia where it is popular by different names. BQ is a unique combination of nut or fruit from the Areca catechu Linn. (AN) tree, leaf from the Piper betle Linn. (BL) vine, slaked lime, paste of bark from the Acacia catechu tree and other spices. AN has been used successfully in various traditional medicines by different civilizations over several ages. Initially condemned by the medical communities for its health hazards, identification and application of potent pharmacologically bioactive compounds from different constituents of BQ have rekindled growing interest in related investigations. Curious about the stimulating role of BQ, we investigated the potential steroidogenic activity of hot water extract from BQ and its constituents and arecoline on testosterone producing ability in an in vitro experiment. Enzyme dissociated interstitial cells from adult mouse testes (ICR strain) were cultured with/without different doses of the extracts and the level of testosterone produced was assayed by an enzyme immunoassay (EIA) technique. It was found that at lower doses of arecoline, AN and BL extracts had significantly stimulated testosterone production over the basal level (p&lt;0.05). BQ extract, on the other hand, did not show any significant effect on testosterone production. Combinations of arecoline at low doses with 10 ng/ml ovine leutinizing hormone (oLH) showed increases in testosterone produced, while cyclic adenosine monophosphate (cAMP) co-culture showed dose-related inhibition. Our current finding hints at the possible dose-dependent dualistic role of AN and BL extracts and arecoline for testosterone production employing possible non-cAMP-dependent pathway of steroidogenesis. However, the identity of the active compounds besides arecoline and the exact mechanism involved remains to be further investigated.
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Matsuo, Yosuke, Rie Kusano, Sosuke Ogawa, Yoshikazu Yazaki та Takashi Tanaka. "Characterization of the α-Amylase Inhibitory Activity of Oligomeric Proanthocyanidins from Acacia mearnsii Bark Extract". Natural Product Communications 11, № 12 (2016): 1934578X1601101. http://dx.doi.org/10.1177/1934578x1601101219.

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Acacia mearnsii (Fabaceae) contains acacia polyphenols, which are a complex mixture of proanthocyanidins that are mainly composed of 5-deoxycatechin units. In this study, an aqueous extract of A. mearnsii bark was fractionated and the α-amylase inhibitory activity of each fraction was evaluated. The 13C NMR and MS data and the pyrolysis products obtained from the active and inactive fractions were compared. The spectroscopic results clearly indicated that fractions with strong inhibitory activity contained proanthocyanidin oligomers with catechol-type B-rings rather than pyrogallol-type B-rings. HPLC analysis of the pyrolysis products showed peaks for pyrocatechol were only observed in the mixtures obtained from the fractions with high inhibitory activities. In addition, (+)-pinitol was isolated as a major polyol of the extract at a level comparable with that of sucrose.
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16

Kumar Reddy M, aswanth, Shivalinge Gowda KP, and Ankit Kumar Arora. "Study of wound healing activity of aqueous and alcoholic bark extracts of Acacia catechu on rats." RGUHS Journal of Pharmaceutical Sciences 1, no. 3 (2011): 220–25. http://dx.doi.org/10.5530/rjps.2011.3.8.

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17

Ogawa, Sosuke, Yosuke Matsuo, Takashi Tanaka, and Yoshikazu Yazaki. "Utilization of Flavonoid Compounds from Bark and Wood. III. Application in Health Foods." Molecules 23, no. 8 (2018): 1860. http://dx.doi.org/10.3390/molecules23081860.

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Dietary supplements ACAPOLIA® and ACAPOLIA PLUS have been sold in Japan under the classification “Foods in General” for a number of years. In April 2015, the classification of “Foods with Function Claims” was introduced in Japan to make more products available to the public that were clearly labeled with functional claims based on scientific evidence. In order to obtain recognition of ACAPOLIA PLUS under this new classification, the following information needed to be established. The safety of the bark extract of Acacia mearnsii was shown from the history of the long-term safe consumption of the extract as a health supplement, together with several additional clinical safety tests. Robinetinidol-(4α,8)-catechin was detected by high performance liquid chromatography (HPLC) in the supplement and was suitable for use as the basis of the quantitative analysis. In clinical tests, the amount of change in the plasma glucose concentration in the initial 60 min after rice consumption by a test group who had been given the Acadia extract was significantly lower than the glucose concentration in the group that was given a placebo. The blood glucose incremental areas under the curve (IAUC) in the first 60 min after rice consumption were also significantly lower in the Acacia group. The functional mechanisms were explained in terms of the inhibition of the absorption of glucose in the small intestine and the reduction in the activity of the digestive enzymes caused by proanthocyanidins derived from A. mearnsii bark. As a result, ACAPOLIA PLUS was accepted as a “Food with Function Claims” in August 2016. ACAPOLIA PLUS is now sold under this new classification. The growth of a typical intestinal bacterium is inhibited by an extract containing flavonoid compounds from A. mearnsii bark; thus, one of the future directions of study must be a comprehensive investigation of the effect that flavonoid compounds, proanthocyanidins, have on intestinal bacteria.
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Alpashree, Syed Kazim Hasan, Johirul Islam, et al. "Colono-protective Potentiality of Methanolic Bark Extract of Acacia catechu: A Medicinal Plant against 1,2-Dimethylhydrazine–Induced Toxicity in Wistar Rats." Journal of Environmental Pathology, Toxicology and Oncology 37, no. 4 (2018): 273–89. http://dx.doi.org/10.1615/jenvironpatholtoxicoloncol.2018026923.

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Yimam, Mesfin, Teresa Horm, Laura Wright, et al. "UP1306: A Composition Containing Standardized Extracts of Acacia catechu and Morus alba for Arthritis Management." Nutrients 11, no. 2 (2019): 272. http://dx.doi.org/10.3390/nu11020272.

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Osteoarthritis (OA) is characterized by progressive articular cartilage degradation. Although there have been significant advances in OA management, to date, there are no effective treatment options to modify progression of the disease. We believe these unmet needs could be bridged by nutrients from natural products. Collagen induced arthritis in rats was developed and utilized to evaluate anti-inflammatory and cartilage protection activity of orally administered botanical composition, UP1306 (50 mg/kg) and Methotrexate (75 µg/kg) daily for three weeks. Objective arthritis severity markers, urine, synovial lavage, and serum were collected. At necropsy, the hock joint from each rat was collected for histopathology analysis. Urinary cartilage degradation marker (CTX-II), pro-inflammatory cytokines (tumor necrosis factor α (TNF-α), interleukin-1β (IL-1β), and IL-6), and proteases (Matrix Metallopeptidase 3 (MMP3) and 13) were measured. Rats treated with UP1306 showed statistically significant improvements in arthritis severity markers, including uCTX-II (91.4% vs. collagen-induced arthritis (CIA)), serum IL-1β, TNF-α, and IL-6 levels as well as synovial MMP-13. The histopathology data were also well aligned with the severity score of arthritis for both UP1306 and Methotrexate. UP1306, a botanical composition that contains a standardized blend of extracts from the heartwood of Acacia catechu and the root bark of Morus alba, could potentially be considered as a dietary supplement product for the management of arthritis.
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Salem, Mohamed Z. M., Abeer A. Mohamed, Hayssam M. Ali, and Dunia A. Al Al Farraj. "Characterization of Phytoconstituents from Alcoholic Extracts of Four Woody Species and Their Potential Uses for Management of Six Fusarium oxysporum Isolates Identified from Some Plant Hosts." Plants 10, no. 7 (2021): 1325. http://dx.doi.org/10.3390/plants10071325.

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Background: Trees are good sources of bioactive compounds as antifungal and antioxidant activities. Methods: Management of six molecularly identified Fusarium oxysporum isolates (F. oxy 1, F. oxy 2, F. oxy 3, F. oxy 4, F. oxy 5 and F. oxy 6, under the accession numbers MW854648, MW854649, MW854650, MW854651, and MW854652, respectively) was assayed using four extracts from Conium maculatum leaves, Acacia saligna bark, Schinus terebinthifolius wood and Ficus eriobotryoides leaves. All the extracts were analyzed using HPLC-VWD for phenolic and flavonoid compounds and the antioxidant activity was evaluated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging and β-carotene-linoleic acid (BCB) bleaching assays. Results: In mg/kg extract, the highest amounts of polyphenolic compounds p-hydroxy benzoic, benzoic, gallic, and rosmarinic acids, with 444.37, 342.16, 311.32 and 117.87, respectively, were observed in C. maculatum leaf extract; gallic and benzoic acids with 2551.02, 1580.32, respectively, in A. saligna bark extract; quinol, naringenin, rutin, catechol, and benzoic acid with 2530.22, 1224.904, 798.29, 732.28, and 697.73, respectively, in S. terebinthifolius wood extract; and rutin, o-coumaric acid, p-hydroxy benzoic acid, resveratrol, and rosmarinic acid with 9168.03, 2016.93, 1009.20, 1156.99, and 574.907, respectively, in F. eriobotryoides leaf extract. At the extract concentration of 1250 mg/L, the antifungal activity against the growth of F. oxysporum strains showed that A. saligna bark followed by C. maculatum leaf extracts had the highest inhibition percentage of fungal growth (IPFG%) against F. oxy 1 with 80% and 79.5%, F. oxy 2 with 86.44% and 78.9%, F. oxy 3 with 86.4% and 84.2%, F. oxy 4 with 84.2, and 82.1%, F. oxy 5 with 88.4% and 86.9%, and F. oxy 6 with 88.9, and 87.1%, respectively. For the antioxidant activity, ethanolic extract from C. maculatum leaves showed the lowest concentration that inhibited 50% of DPPH free radical (3.4 μg/mL). Additionally, the same extract observed the lowest concentration (4.5 μg/mL) that inhibited BCB bleaching. Conclusions: Extracts from A. saligna bark and C. maculatum leaves are considered potential candidates against the growth of F. oxysporum isolates—a wilt pathogen—and C. maculatum leaf as a potent antioxidant agent.
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Guleria, Sanjay, A. K. Tiku, Gurjinder Singh, Dhiraj Vyas, and Ashwani Bhardwaj. "Antioxidant Activity and Protective Effect Against Plasmid DNA Strand Scission of Leaf, Bark, and Heartwood Extracts from Acacia catechu." Journal of Food Science 76, no. 7 (2011): C959—C964. http://dx.doi.org/10.1111/j.1750-3841.2011.02284.x.

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22

Ahmadu, Augustine, Abdulkarim Agunu, Thi-Ngoc-Dung Nguyen, et al. "Constituents of Acacia nilotica (L.) Delile with Novel Kinase Inhibitory Activity." Planta Medica International Open 4, no. 03 (2017): e108-e113. http://dx.doi.org/10.1055/s-0043-122397.

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Abstract Acacia nilotica (L.) Delile belongs to the genus Acacia, which includes about 1400 species in subtropical and tropical Africa including Nigeria, Senegal, Egypt, and Mozambique as well as Asia from India to Burma. This plant is traditionally used to treat several pathologies such as mouth, ear, and bone cancer. Moreover, it possesses many other biological activities (antidiarrheal, anti-inflammatory, antimicrobial, and antifungal). We report here the extraction, purification, and identification of two known compounds [ethylgallate and (+)-catechin] from the bark of the tree that were further tested for their inhibitory activities against a panel of disease-related protein kinases. Both compounds were active, and (+)-catechin showed the best activity by inhibiting nine out of fourteen protein kinases with an IC50 value in the µg/mL range. This compound gave the highest activity against CLK1 with an IC50 of 2.1 µg/mL. The ethyl acetate extract and its components, such as catechins and other polyphenols, which also had protein kinase inhibitory activity, can be exploited in the research for anticancer agents.
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Lakshmi, Thangavelu, Balusamy Sri Renukadevi, Sivanesan Senthilkumar, et al. "Seed and bark extracts of Acacia catechu protects liver from acetaminophen induced hepatotoxicity by modulating oxidative stress, antioxidant enzymes and liver function enzymes in Wistar rat model." Biomedicine & Pharmacotherapy 108 (December 2018): 838–44. http://dx.doi.org/10.1016/j.biopha.2018.08.077.

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Ikarashi, Nobutomo, Takahiro Toda, Takehiro Okaniwa, Kiyomi Ito, Wataru Ochiai, and Kiyoshi Sugiyama. "Anti-Obesity and Anti-Diabetic Effects of Acacia Polyphenol in Obese Diabetic KKAy Mice Fed High-Fat Diet." Evidence-Based Complementary and Alternative Medicine 2011 (2011): 1–10. http://dx.doi.org/10.1093/ecam/nep241.

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Acacia polyphenol (AP) extracted from the bark of the black wattle tree (Acacia meansii) is rich in unique catechin-like flavan-3-ols, such as robinetinidol and fisetinidol. The present study investigated the anti-obesity/anti-diabetic effects of AP using obese diabetic KKAy mice. KKAy mice received either normal diet, high-fat diet or high-fat diet with additional AP for 7 weeks. After the end of administration, body weight, plasma glucose and insulin were measured. Furthermore, mRNA and protein expression of obesity/diabetic suppression-related genes were measured in skeletal muscle, liver and white adipose tissue. As a result, compared to the high-fat diet group, increases in body weight, plasma glucose and insulin were significantly suppressed for AP groups. Furthermore, compared to the high-fat diet group, mRNA expression of energy expenditure-related genes (PPARα, PPARδ, CPT1, ACO and UCP3) was significantly higher for AP groups in skeletal muscle. Protein expressions of CPT1, ACO and UCP3 for AP groups were also significantly higher when compared to the high-fat diet group. Moreover, AP lowered the expression of fat acid synthesis-related genes (SREBP-1c, ACC and FAS) in the liver. AP also increased mRNA expression of adiponectin and decreased expression of TNF-αin white adipose tissue. In conclusion, the anti-obesity actions of AP are considered attributable to increased expression of energy expenditure-related genes in skeletal muscle, and decreased fatty acid synthesis and fat intake in the liver. These results suggest that AP is expected to be a useful plant extract for alleviating metabolic syndrome.
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Wie Lawa, Emma Dyelim, and Edwin J. L. Lazarus. "SUPLEMENTASI TEPUNG IKAN TERPROTEKSI EKSTRAK TANIN HIJAUAN KABESAK KUNING, KABESAK HITAM DAN KIHUJAN DALAM RANSUM TERHADAP PERTUMBUHAN TERNAK KAMBING." ZOOTEC 35, no. 2 (2015): 368. http://dx.doi.org/10.35792/zot.35.2.2015.9456.

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SUPPLEMENTATION OF FISH MEAL PROTECTED OF TANNIN EXTRACT FROM ACACIA LEUCOPHLOEA, ACACIA CATECHU AND SAMANEA SAMAN IN RATION ON GOAT PERFORMANCE. The objective of research was to study supplementation of fish meal protected of tannin extract from Acacia leucophloea, Acacia catechu and Samanea saman in ration on goat performance. The experiment was arranged in Completely Randomized Design with 4 treatments and 4 replicates. Sixteen male local goats were allocated for treatments: P0 (basal feed + corn-urea + non protected fish meal with extract tannin), P1 (basal feed + corn-urea + protected fish meal with extract tannin from Acacia leucophloea), P2 (basal feed + corn-urea + protected fish meal with extract tannin from Acacia catechu), and P3 (basal feed + corn-urea + protected fish meal with extract tannin from Samanea saman). Combination native grass with Leucaena used as basal feed (60:40). The result of experiment showed that the treatments effective in increasing goat performance and the best treatment were supplementation fish meal with extract tannin from Acacia leucophloea (DMI 719,88 g/h/d; N retention 10,46 g/h/d; daily gain 52,94 g/h/d and ration efficiency 0,070) and Acacia catechu (DMI 719,88 g/h/d; N retention 10,03; daily gain 51,47 g/h/d and ration efficiency 0,072). Keywords : supplementation, fish meal, protection, tannin extract, goat performance
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Waseem, Uzma, Tayyaba Mahmud, Natasha Nadeem, et al. "Role of Acacia Catechu in Regulating Connective Tissue Components during Experimental Gastric Ulcer Healing." Pakistan Journal of Medical and Health Sciences 16, no. 7 (2022): 181–83. http://dx.doi.org/10.53350/pjmhs22168181.

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Aim: To determine the healing properties of different doses of Acacia catechu on histopathological changes induced by aspirin in the stomach of adult albino rats. Methods: In an experimental study which was carried out at Postgraduate Medical Institute for a period of 21 days, forty-eight adult albino rats were included. The animals were divided into four groups by ballottement. Every group was further subdivided into three groups based on the day of sacrifice. BDH (British drug houses) provided Aspirin in powder form, and the bark of Acacia catechu was obtained from Government College University (Botany Department). The study was approved by institutional Ethical Review Committee. Results: Increased number of fibroblasts were seen in the groups taking acacia catechu, signifying healing, compared to aspirin only group. After applying one-way ANOVA, a statistically significant difference was observed among the groups on day 7 and day 14 (P-value &lt;0.01*). However, on day 3, an insignificant difference was seen among the groups (P-value = 0.97). Conclusion: Acacia catechu has a protective role against aspirin-induced gastric injury, by inhibiting inflammation. Keywords: Fibroblast, Acacia catechu, ulcer, wound healing.
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Isemura, Mamoru. "Catechin in Human Health and Disease." Molecules 24, no. 3 (2019): 528. http://dx.doi.org/10.3390/molecules24030528.

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Khare, Basant, Naina Dubey, and Akash Sharma. "ANTIULCER ACTIVITY OF CONTROLLED RELEASE FORMULATION CONTAINING AQUEOUS EXTRACT OF ACACIA CATECHU WILLD ON RODENT MODELS." International Journal of Current Pharmaceutical Research 10, no. 5 (2018): 25. http://dx.doi.org/10.22159/ijcpr.2018v10i5.29689.

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Objective: To study the Antiulcer activity of aqueous extract of acacia catechu willd on rodent models by controlled release formulation.Methods: Microspheres were prepared by solvent evapoaration method and were evaluated for various parameters like SEM, stability and in vitro relese. And acacia catechu willd loaded microspheres were evaluated for in vivo study involving Gastric ulceration in rats was induced by Ethanol/HCl. Ulcer genic effect (Ulcer Index), pH and Total acidity, Histopathological studies.Results: Results indicated that Acacia catechu willd microspheres contains some active constituents like flavanoid which are responsible for its anti ulcer activity. Also it was observed aqueous extract loaded microspheres showed maximum activity was found (200 mg/kg) with standard Cimetidine (100 mg/kg) also, the results revealed that aqueous extract microspheres at 200 mg/kg had reduced ulcer incidence significantly, when compared to the control as evident by decrease in ulcer score in the model.Conclusion: Based on the result it can be concluded that microspheres loaded with aqueous extracts of Acacia catechu willd produced promising antiulcer activity and were safe.
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Hye, M. A., M. A. Taher, M. Y. Ali, M. U. Ali, and Shahed Zaman. "Isolation of (+)-Catechin from Acacia Catechu (Cutch Tree) by a Convenient Method." Journal of Scientific Research 1, no. 2 (2009): 300–305. http://dx.doi.org/10.3329/jsr.v1i2.1635.

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Biologically important polyphenol (+)-catechin was isolated from catechu, the extract of the red heartwood of Acacia Catechu tree (Khoiyer tree). The isolation procedure was developed to get better yield (25%) and to reduce the isolation cost and time. The structure of the isolated (+)-catechin was confirmed with several spectral analyses and chemical studies. Keywords: Acacia Catechu; (+)-catechin; Polyphenol. © 2009 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. DOI: 10.3329/jsr.v1i2.1635
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Pathak, Sunil, and Babita Suman. "Studies on Fungal Associates of Acacia catechu (L.f.) Willd. – A Medicinal Plant." ECOLOGY, ENVIRONMENT AND CONSERVATION 30, no. 05 (2024): S188—S192. http://dx.doi.org/10.53550/eec.2024.v30i05s.030.

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Fungal associates of Acacia catechu growing in district Hamirpur of Himachal Pradesh were studied, identified and are being reported in the present research paper. The rhizosphere of Acacia catechu revealed the presence of twenty three species of fungi. Seven species ofAMF (Arbuscular Mycorrhizal Fungi) belonging to three genera (Acaulospora, Gigaspora and Glomus) were isolated from roots adhering soil. Leaves and bark of this plant revealed the presence of three endophytic fungal species belonging to three genera namely, Aspergillus niger, Cladosporium cladosporioides and Fusarium solani. Further research of endophytes can be beneficial for the production of secondary metabolites and for bioprospecting.
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Waseem, Uzma, Syeda Rizwana Jafri, Sarah Khalid, Fauzia Qureshi, Nadia Majeed, and Ursula Akif. "Anti-inflammatory activity of acacia catechu-bark aqueous solution in aspirin induced gastric ulcer in rodents." International Journal Of Community Medicine And Public Health 8, no. 12 (2021): 5649. http://dx.doi.org/10.18203/2394-6040.ijcmph20214551.

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Background: Aspirin is amongst the most widely used drugs and has many adverse effects on gastric mucosa. Anti-inflammatory properties of Acacia catechu have been established already. Objective was to evaluate the histopathological changes induced by aspirin in the stomach of albino rats and to assess the protective effect of different doses of Acacia catechu.Methods: Experimental study Postgraduate Medical Institute, Lahore for 21 days. Forty-eight adult albino rats, both males and female, were divided into four groups A, B, C and D randomly; each comprising of 12 rats. Group A was control, group B was given aspirin 100 mg/kg and group C and D were given aspirin 100 mg/kg along with Acacia catechu 250 mg/kg and 500 mg/kg respectively by oral route. The rats from individual group were sacrificed on 3rd day, 7th day and 14th day and stomachs were examined under light microscope to observe the inflammatory cells infiltration.Results: Gross and microscopic findings on days 3, 7 and 14 were similar. Control groups A1, A2 and A3 showed normal healthy gastric mucosa and the least number of inflammatory cells. In group B, aspirin produced ulcerations and linear breaks; with highest inflammatory infiltrates. On microscopic examination, numerous inflammatory cells were noted. Group C and D rats had minimum ulcer index and fewer inflammatory cells.Conclusions: Acacia catechu has protective role against gastric injury by inhibiting inflammation.
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HOSSEN, Kawsar, and Hisashi KATO-NOGUCHI. "Determination of allelopathic properties of Acacia catechu (L.f.) Willd." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 48, no. 4 (2020): 2050–59. http://dx.doi.org/10.15835/nbha48412104.

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Plants possessing allelopathic potential could be used as a source of bio-herbicide to help decrease the use of synthetic herbicides. Acacia catechu (L.f.) Willd., a deciduous tree from the Mimosaceae family, has been reported to have medicinal properties. However, there have been no reports on the allelopathy of this tree. Therefore, the leaf extracts of A. catechu were examined for allelopathic potential using six concentrations: 0.001, 0.003, 0.01, 0.03, 0.1, and 0.3 g dry weight equivalent extract mL-1. The aqueous methanol extracts of A. catechu significantly suppressed the seedling growth of six test plants such as alfalfa, cress, lettuce, barnyard grass, Italian ryegrass, and timothy. The extracts inhibited the six test plants in a concentration-dependent manner. The shoot and root growth of all the test plant species were completely inhibited from the concentration of 0.3 g of dry weight equivalent extract mL-1, except the shoot growth of barnyard grass. Concentrations needed for 50% growth inhibition (I50 values) ranged from 0.004 to 0.043 g dry weight equivalent extract mL-1 for shoot growth, and 0.003 to 0.019 g dry weight equivalent extract mL-1 for root growth. Moreover, the I50 values indicated that the root growth of all the test plants was more susceptible to the A. catechu extracts than the shoot growth. The inhibitory effects of the extracts of A. catechu suggest that the extracts may contain allelopathic potential and, therefore, may be a potential candidate for the isolation and characterization of allelochemicals to develop an ecofriendly bio-herbicide.
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Mishra, Pawan, Sabin Aryal, Hari Oli, et al. "Enhanced Energy Storage: Electrochemical Performance of ZnCl<sub>2</sub>-Activated Carbon Derived from Acacia catechu Bark." Mongolian Journal of Chemistry 25, no. 52 (2024): 26–34. https://doi.org/10.5564/mjc.v25i52.3501.

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In this study, Acacia catechu bark is used for the development of advanced supercapacitor negatrode materials through the synthesis of activated carbon via activation and carbonization at varying temperatures (400, 600, 800 °C) using ZnCl2 as the activating agent. The as-prepared sample is characterized using X-ray diffraction (XRD), Fourier-transform infrared (FTIR) techniques. The specific surface area was evaluated using BET analysis, while 3D morphological assembly of the resulting material was assessed by means of the Field Emission Scanning Electron Microscopy. Cyclic voltammetry, galvanostatic charging and discharging, electrochemical impedance, were conducted to evaluate the material's electrochemical performance. The activated carbon prepared at 800°C (BZAC-8) exhibited a specific capacitance of 259.34 F g-1 at a current density of 1 A g-1 with excellent capacity retention (92.61%) and lower impedance. These findings underscore the potential of utilizing Acacia catechu bark-based active carbon as a negatrode material for advanced energy storing application.
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ram, Dr Sukha, Dr Ritu Sharma, Prof Mita Kotecha, and Dr Krutika Chaudhary. "Preliminary Pharmacognosy Evaluation of The Bark of Acacia Catechu(Wild.)." International Research Journal of Ayurveda & Yoga 04, no. 04 (2021): 01–09. http://dx.doi.org/10.47223/irjay.2021.4420.

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Pawar, Reshma, and A. Balasubramaniam. "Densitometric HPTLC analysis of the Acacia catechu wild fractions for phenolics." International Journal of Experimental Research and Review 32 (August 30, 2023): 260–69. http://dx.doi.org/10.52756/ijerr.2023.v32.022.

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Traditional "Ayurvedic" medicine from India has traditionally used Acacia catechu. The herbal extract is the primary component, although there have been no attempts to standardize it as an active agent or marker. A chromatographic fingerprint represents the chemical components of herbal remedies that are therapeutically advantageous. This study suggests utilizing an HPTLC approach to assess phenols like protocatechuic acid and gallic acid in Acacia catechu extract fractions made of water, ethyl acetate, and butanol. According to the study, protocatechuic acid (11.85%) in the water fraction of the Acacia catechu is more concentrated than gallic acid (6.92%). In contrast, the ethyl acetate fraction contains more gallic acid (11%) and less protocatechuic acid (4.10%). However, the butanol fraction only has 6.62% gallic acid. By the Folin-Coicalteu method, total phenolic content was determined, and antioxidant activity of all fractions was resolute using the DPPH method. It was discovered that ethyl acetate fraction had higher phenolic content (211 mg/g) than aqueous fraction (129 mg/g) and butanol fraction (101.2 mg/g). Ethyl acetate fraction has more potent antioxidant activity than water and Butanol fractions. The research emphasizes the potential of this methodology for efficient and economical phenolic profiling, which may aid in the assessment and use of A. catechu in the nutraceutical and pharmaceutical sectors.
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D’souza, Prima, Rajendra Holla, and Gangadhara Swamy. "Amelioration of Diabetic Nephropathy in Streptozotocin-Induced Diabetic Rats by Acacia catechu Leaves Extract." Journal of Health and Allied Sciences NU 09, no. 03 (2019): 116–20. http://dx.doi.org/10.1055/s-0039-3402084.

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Abstract Objective The present study was performed to evaluate the ethanolic extract of leaves of Acacia catechu (A. catechu) for its effect on streptozotocin (STZ)-induced diabetes mellitus (DM) and its renal complications in male Wistar albino rats. Materials and Methods Male Wistar albino rats were grouped into control (A), STZ-induced DM (B), STZ-induced DM rats with A. catechu orally of 75 mg/kg body weight (kbw) for 35 days (C), with each group having six rats (n = 6) weighing between 200 to 250 g each. Group A receives only water, orally; group B receives a single dose of STZ at 45 mg/kbw intraperitoneal administration (IP); group C receives STZ IP and oral A. catechu for 35 days. On the 36th day, animals were euthanized, the kidney tissues were analyzed for biochemical parameters, such as GOT (glutamic oxaloacetic transaminase), GPT (glutamic pyruvic transaminase), oxidative stress assessment parameters, and histopathological studies. Results In group C rats, activities of the enzymes were nearer to group A when compared with group B. Histopathological findings were also suggesting that renal toxicity were observed at a lesser extent in group C. Conclusion The ethanolic extract of A. catechu signified as nephroprotective effect. The present data could provide adequate confirmation of the efficacy of ethanolic extract of leaves of A. catechu for further experimental studies on a standardized formulation.
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Naznin, Marufa, Md Zainul Abedin, Mubarak Ahmad Khan, and Md Abdul Gafur. "Influence of Acacia catechu Extracts and Urea and Gamma Irradiation on the Mechanical Properties of Starch/PVA-Based Material." ISRN Polymer Science 2012 (October 16, 2012): 1–8. http://dx.doi.org/10.5402/2012/348685.

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This work was aimed to study the effect of natural polyphenol extract (Acacia catechu) on physicochemical properties of starch/PVA-based film. Acacia catechu extracts were incorporated in the starch/PVA- (60 : 40%) based films at different concentrations (0.1% to 15%) to the total weight of starch/PVA-based film. The tensile strength (TS) of the starch/PVA blend film was 24 MPa and significantly increased (33.8 MPa) by the addition of acacia (0.5%). Different percentages of urea (1% to 15%) were incorporated in the starch/PVA/acacia-based film. The best tensile strength (11 MPa) and elongation at break (59%) were obtained at 5% urea concentration. This 5% urea-incorporated film was irradiated at different radiation doses; the film showed the best results at 100 krad (tensile strength 15 MPa and elongation at break 69%). Molecular interactions due to incorporation of Acacia catechu were supported by FTIR spectroscopy. Thermal properties (TG/DTA) of all the films were carried out successfully. Water absorption trend of all the films was comparatively high. Urea-incorporated film degraded 94%, and irradiated urea incorporated film degraded 91% within 70 days into the soil.
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Gusti, Diah Riski, Anjelli Putri Gunawan, Damris Muhammad, and Intan Lestari. "A MIXTURE OF ACACIA BARK EXTRACT (Acacia mangium Willd) AND POTASSIUM IODIDE AS A CORROSION INHIBITOR IN SULFURIC ACID SOLUTION." al-Kimiya 10, no. 2 (2023): 64–73. http://dx.doi.org/10.15575/ak.v10i2.26187.

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Corrosion is a decrease in the quality of a metal material caused by a reaction with the environment. Corrosion cannot be eliminated, but corrosion can be slowed down in several ways by adding corrosion inhibitors and synergistic effects. Acacia bark extract (Acacia mangium Willd) with the addition of 0.02 M KI has the potential as a corrosion inhibitor for steel because it contains secondary metabolites, so it can provide a synergistic effect and increase the value of inhibition efficiency on steel. This research aimed to analyze the effect of a mixture of acacia bark extracts (Acacia mangium Willd) with the addition of KI on inhibition efficiency corrosion of mild steel in sulfuric acid media. The method used in this study is the method of weight loss, adsorption isotherms, and thermodynamic parameters, which were carried out by varying the concentration of acacia bark extract and the immersion temperature of the steel. To strengthen the research results, characterization was carried out using FTIR and SEM. The results showed that the corrosion rate of mild steel immersed in 0.75 M H2SO4 corrosive medium with the addition of 0.02 M KI increased with increasing immersion temperature. These results are reinforced by the results of FTIR and SEM analysis which show that there is an interaction between mild steel and acacia bark extract (Acacia mangium Willd) and KI 0.02 M. Based on the thermodynamic parameters, the resulting values of ∆Hads, ∆Gads, and ∆Sads show that the adsorption process of acacia bark extract (Acacia mangium Willd) in corrosive medium H2SO4 0.75 M with the addition of 0.02 M KI took place spontaneously, showing the type of physical adsorption, adsorbed stable, the adsorption process was exothermic and the degree of irregularity in the adsorption process. The inhibition efficiency of acacia bark extract (Acacia mangium Willd) with the addition of 0.02 M KI was highest at 60 °C with an extract concentration of 2.5 g/L of 81%. The higher the immersion temperature, the greater the resulting synergistic effect
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Kathan, Agravat* Jyoti Chauhan Bharat Maitreya. "Exploring the Phytochemical Composition and Antioxidant Properties of Acacia paradoxa, Acacia nilotica, and Acacia auriculiformis Barks." International Journal of Scientific Research and Technology 2, no. 4 (2025): 71–78. https://doi.org/10.5281/zenodo.15169422.

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This research evaluates into the comprehensive phytochemical analysis and antioxidant potential assessment of Bark- Acacia nilotica, Acacia auriculiformis, Acacia paradoxa. These species are renowned for their rich diversity of Secondary metabolites, including Alkaloids, Saponins, Phenol, Tannins, Terpenoids. This Study demonstrates the Total Phenolic Content, Total Tannin Content and Total Flavonoid Content and Antioxidant Capacity of Acacia Bark. Acacia auriculiformis exhibited the highest TPC in Acetone extract 5270.2 &plusmn;0.01 mg GAE/g. Acacia auriculiformis exhibited the highest TFC in Acetone extract 2473.25 &plusmn;0.07 mg TA/g. Acacia auriculiformis Shows the Highest TTC in Acetone extract 245.14 &plusmn;0.02 mg QE/g. Methanol extract shows the Highest DPPH scavenging activity 61% at 1000 &micro;g/ml in Acacia paradoxa. Acetone extract shows the Highest DPPH scavenging activity 71.82 % at 1000 &micro;g/ml in Acacia nilotica. The results show that solvents are effective at extracting bioactive chemicals, as shown by the observation that lower IC50 values indicate that they are more effective at eliminating of free radicals.
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Li, Xing Cui, Li Xin Yang, Hong Qing Wang, and Ruo Yun Chen. "Phenolic compounds from the aqueous extract of Acacia catechu." Chinese Chemical Letters 22, no. 11 (2011): 1331–34. http://dx.doi.org/10.1016/j.cclet.2011.07.014.

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Tangeti, Sunitha, Padmaja Gabbita, Raghunatha R. Ponnaluri, and Bhanu P. Kolasani. "Comparative study of wound healing effect of topical Acacia catechu extract and silver sulfadiazine on excisional wound model in guinea pigs." International Journal of Basic & Clinical Pharmacology 7, no. 12 (2018): 2347. http://dx.doi.org/10.18203/2319-2003.ijbcp20184844.

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Background: Impaired and aberrant wound healing imposes a huge financial burden and places an enormous drain in health care resources in the developed world and an insurmountable problem in the developing countries too. In this study, authors have compared the wound healing effect of topical application of Acacia catechu extract with silver sulfadiazine in excisional wound model in guinea pigs.Methods: Twelve guinea pigs were randomly divided into two groups (n=6). The wound healing was observed in excision model. The standard group is treated with silver sulfadiazine (group 1) and the test group with Acacia catechu extract (group 2). The mean wound size expressed in mm2 and the mean percentage of the wound healed was measured on day 0, 4, 8, 12, 16 and 19. Biopsy was done on day 21 for histopathological examination (HPE).Results: Statistical analysis was done by using unpaired t test for between the groups comparison and by using paired t test for within the group comparison. The mean percentage of the wound healed with-in the groups was found to be statistically highly significant (p value &lt;0.001) and in between the groups was found to be statistically non-significant (p value &gt;0.05). A comparable increase in collagen content and granulation tissue was found on HPE in both the groups on day 21.Conclusions: Wound healing effect of the Acacia catechu extract is equal to and comparable with that of silver sulfadiazine.
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Theng, Madhuri A., G. R. Sitaphale, and K. R. Biyani. "EVALUATION OF WOUND HEALING ACTIVITY OF POLYHERBAL FORMULATION." International Journal of Current Pharmaceutical Research 9, no. 6 (2017): 12. http://dx.doi.org/10.22159/ijcpr.2017v9i6.23420.

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Objective: The present study describes the anti-microbial acivity of Acacia arabica and Butea monosperma bark extract.Methods: For this purpose aqueous extract of bark were prepared by “Soxhlet extraction method”. The experimentally induced burn wound model in rats by “Excision method”.Results: As a result of this study it was found that the extract of bark generally revealed antimicrobial and wound healing activity.Conclusion: The result of the study suggest that the Acacia arabica and Butea monosperma bark of polyherbal gel effective in accelerating wound healing process.
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Balu, Ramesh, and Jayabharathi V. "IN VITRO ANTIOXIDANT AND ANTIHYPERGLYCEMIC ACTIVITIES OF HYDROETHANOLIC LEAF EXTRACT OF ACACIA CATECHU (L.F) WILLD." Asian Journal of Pharmaceutical and Clinical Research 10, no. 11 (2017): 190. http://dx.doi.org/10.22159/ajpcr.2017.v10i11.20299.

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Objective: The aim of this study was to analyze the antioxidant and antihyperglycemic activities of hydroethanolic leaf extract of Acacia catechu (L.f) Willd. Methods: The A. catechu (L.f) Willd. leaf extract was subjected to antioxidant activities such as 1,1-diphenyl-1-picryl hydrazyl (DPPH), hydroxyl radical (OH−), nitric oxide radical (NO−), and superoxide radical (SO) scavenging assays. Further, the leaf extract was subjected to antihyperglycemic activity by α-amylase inhibition assay.Results: The free radical scavenging activity of the plant extract was found to increase with increase in concentration (20-100 μg/ml) and the maximum activity was obtained at 100 μg/ml, which was compared with the standard ascorbic acid. The percentage inhibition of free radicals was found to be 62.94±0.91%, 63.53±1.08%, 71.04±0.48%, and 51.50±0.86% for DPPH, OH−, NO−, and SO−, respectively. The IC50 for DPPH, OH−, NO−, and SO were recorded as 73.81±0.95, 69.03±0.58, 60.74±0.37, and 83.10±1.00 μg/ml. The IC50 value of α-amylase inhibitory activity was found to be 71.17 μg/ml.Conclusion: The present investigations suggest that the A. catechu (L.f) Willd may serve as a potential source of natural antioxidant and antihyperglycemic agent that could have great importance in pharmaceutical preparations.
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Deshmukh, Mahendra A., and Madhuri A. Theng. "PHYTOCHEMICAL SCREENING, QUANTITATIVE ANALYSIS OF PRIMARY AND SECONDARY METABOLITES OF ACACIA ARABICA BARK." International Journal of Current Pharmaceutical Research 10, no. 2 (2018): 35. http://dx.doi.org/10.22159/ijcpr.2018v10i2.25889.

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The study includes phytochemical screening and quantification of primary and secondary metabolites like chlorophyll, carbohydrates, protein, lipids, phenol, tannin and flavonoids from Acacia arabica bark. For these purpose aqueous extract of bark was prepared by “Soxhlet extraction method”. The result of these study suggests that the Acacia arabica bark in which presence of primary and secondary metabolites.
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Mutiar, Sri, and Anwar Kasim. "Potential and Application of Vegetable Tanning Materials from Industrial Forest Plantation in Indonesia." Journal of Fibers and Polymer Composites 2, no. 1 (2023): 29–45. http://dx.doi.org/10.55043/jfpc.v2i1.62.

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Vegetable tanning materials are sourced from plants that contain tannin compounds. Tannins are obtained through the extraction method from the roots, stems, bark, or fruit of the original plant. There are several forest management companies in Indonesia that produce wood from plant species Acacia auriculiformis and Acacia mangium. Both species are known as Acacia. Acacia is an important source of tannin for material tanner vegetables. This wood is produced as a raw material for the pulp and paper industry. However, the bark contains tannin and has not been used optimally. Therefore, the study's potential and possible applications as vegetable tanning agents have been carried out. The research was started by investigating the availability of bark and extracting tannins to obtain extracts containing tannins. Furthermore, the extract obtained was applied as a vegetable tanning agent for the goatskin tanning process. The results showed that the bark of the Plant Industry Forest has the potential to be developed as a source of tannins for material vegetable tanning agents. The application of acacia bark extract in goatskin tanning has obtained tanned leather that meets the Indonesian National Standard.
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Kumari, Monika, Radha, Manoj Kumar, et al. "Acacia catechu (L.f.) Willd.: A Review on Bioactive Compounds and Their Health Promoting Functionalities." Plants 11, no. 22 (2022): 3091. http://dx.doi.org/10.3390/plants11223091.

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With the advent of pandemics and infectious diseases, numerous research activities on natural products have been carried out to combat them. Researchers are investigating natural products for the treatment and/or management of various infectious diseases and/or disorders. Acacia catechu (L.f.) Willd. belongs to the family Fabaceae (subfamily Mimosoideae) known as Khair or Cutch tree, possesses diverse pharmacological actions, and has been widely used in Asia and different parts of the world. The purpose of the present study is to highlight the phytochemical profile of different parts of A. catechu, the different biological activities of A. catechu extract, and the utilization of A. catechu as food and beverage. The present work constitutes a review of A. catechu; we performed searches (books, Google, Google Scholar, and Scopus publications) to compile the work/investigations made on A. catechu to the present. From our survey, it was concluded that the main phytochemicals compounds in A. catechu are protocatechuic acid, taxifolin, epicatechin, epigallocatechin, catechin, epicatechin gallate, procyanidin, phloroglucin, aldobiuronic acid, gallic acid, D-galactose, afzelchin gum, L-arabinose, D-rhamnose, and quercetin. The whole plant of A. catechu possesses a comprehensive variety of medicinal potentials such as antimicrobial, antidiarrheal, antinociceptive, antihyperlipidemic, antiulcer, antioxidant, antidiabetic, antiproliferative, haemolytic, and anti-inflammatory properties due to the presence of bioactive compounds like flavonoids, alkaloids, and tannins. However, even though the plant’s metabolites were reported to have many different pharmacological uses, there is limited information about their toxicity or clinical trials. Further research on diverse metabolites of A. catechu should be carried out to ensure the safety or utilization of this plant in the pharma or food industries and in the development of potent plant-based drugs.
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47

Kim, Dong-Gyu, Min Jung Kang, Hwa Jin Suh, Oh Oun Kwon, and Jung Hye Shin. "Effect of Acacia catechu Extract on 3T3-L1 Preadipocyte Differentiation." Journal of the Korean Society of Food Science and Nutrition 45, no. 8 (2016): 1107–13. http://dx.doi.org/10.3746/jkfn.2016.45.8.1107.

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48

Aryal, Babita, Bikash Adhikari, Niraj Aryal, Bibek Raj Bhattarai, Karan Khadayat, and Niranjan Parajuli. "LC-HRMS Profiling and Antidiabetic, Antioxidant, and Antibacterial Activities of Acacia catechu (L.f.) Willd." BioMed Research International 2021 (August 13, 2021): 1–16. http://dx.doi.org/10.1155/2021/7588711.

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Acacia catechu (L.f.) Willd is a profoundly used traditional medicinal plant in Asia. Previous studies conducted in this plant are more confined to extract level. Even though bioassay-based studies indicated the true therapeutic potential of this plant, compound annotation was not performed extensively. This research is aimed at assessing the bioactivity of different solvent extracts of the plant followed by annotation of its phytoconstituents. Liquid chromatography equipped with high resolution mass spectrometry (LC-HRMS) is deployed for the identification of secondary metabolites in various crude extracts. On activity level, its ethanolic extract showed the highest inhibition towards α-amylase and α-glucosidase with an IC50 of 67.8 ± 1 μg/mL and 10.3 ± 0.1 μg/mL respectively, inspected through the substrate-based method. On the other hand, the plant extract showed an antioxidant activity of 23.76 ± 1.57 μg/mL, measured through radical scavenging activity. Similarly, ethyl acetate and aqueous extracts of A. catechu showed significant inhibition against Staphylococcus aureus with a zone of inhibition (ZoI) of 13 and 14 mm, respectively. With the LC-HRMS-based dereplication strategy, we have identified 28 secondary metabolites belonging to flavonoid and phenolic categories. Identification of these metabolites from A. catechu and its biological implication also support the community-based usage of this plant and its medicinal value.
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49

Joshi, Susan, Yagya Prasad Subedi, and Shobha Kumari Paudel. "Antibacterial and Antifungal Activity of Heartwood of Acacia catechu of Nepal." Journal of Nepal Chemical Society 27 (August 22, 2012): 94–99. http://dx.doi.org/10.3126/jncs.v27i1.6667.

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Antibacterial activity of different extracts of heartwood of Acacia catechu were tested against 11 species of bacteria and antifungal activity were tested against four species of fungi. Among bacteria species highest zone of inhibition (ZOI) was measured against Pseudomonas species by diethyl ether extract, likewise among fungal organism highest zone of inhibition (ZOI) was measured against Fusarium oxysporim by ethyl acetate extract. No extracts showed activity against Salmonella typhi, Salmonella paratyphi, Escherichia coli and Proteus mirabilis. The minimum bactericidal concentration (MBC) of ethyl acetate extract was evaluated against Bacillus subtilis, Klebsiella pneumonia, Staphylococus aureus and Shigella species.DOI: http://dx.doi.org/10.3126/jncs.v27i1.6667 J. Nepal Chem. Soc., Vol. 27, 2011 94-99
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50

Jodi, S. M., N. Umar, H. Y. Ungo-kore, and Y. B. Ngwai. "ANTIMICROBIAL ACTIVITY OF ACACIA NILOTICA AGAINST SOME BACTERIAL ISOLATES ASSOCIATED WITH WOUND INFECTIONS." FUDMA JOURNAL OF SCIENCES 4, no. 2 (2022): 807–11. http://dx.doi.org/10.33003/fjs-2000-0402-1010.

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The search for biologically active compounds extracted from traditionally used plants is relevant due to the increasing resistance of bacteria to synthetic antibiotics and the occurrence of fatal opportunistic infections. Acacia nilotica, of the family leguminosae, is one of the oldest existing plant species having various therapeutic, biological and ethno-botanical claims and has diverse medicinal properties. This study was designed to determine the antimicrobial activity of leaf and stem-bark extract of Acacia nilotica against some bacterial isolates associated with wound infections. Leaf and stem-bark of Acacia nilotica plant was collected, identified, dried and extracted with 100% ethanol. The antimicrobial activity of the extracts and the fractions were evaluated against Staphylococcus aureus (SA), Bacillus subtilis (BS), Pseudomonas aeruginosa (PA) and Escherichia coli (EC) using agar well diffusion technique. Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) of the leaf and stem-bark extract was determined using microbroth dilution method. Phytochemical screening was carried out on the extracts and the leaf extract was subjected to liquid-liquid fractionation where n-hexane, ethyl acetate and residual aqueous fractions were obtained. The leaf and stem-bark extracts of Acacia nilotica were both active against the test organisms, but the leaf extract was more active. Antimicrobial activity against SA was the highest (at diameter zone of inhibition of 32.00±0.00 mm); and was observed in with the leaf extract. The MICs of the extracts against the organisms were 15.6-31.3 mg/ml (leaf) and 125 mg/ml (stem-bark); and the MBCs were 31.3 mg/ml (leaf) and 250 mg/ml (stem-bark). Tannins, flavonoids, phenols
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