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Journal articles on the topic 'Accumulation antioxidants'

Author: Grafiati

Published: 28 May 2022

Last updated: 30 July 2025

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1

Wei, Lingzhi, Huabo Liu, Yang Ni, et al. "FaAKR23 Modulates Ascorbic Acid and Anthocyanin Accumulation in Strawberry (Fragaria × ananassa) Fruits." Antioxidants 11, no. 9 (2022): 1828. http://dx.doi.org/10.3390/antiox11091828.

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Strawberry (Fragaria × ananassa) fruits are rich in ascorbic acid (AsA) and anthocyanin, which are essential antioxidants for human health. However, the underlying regulatory mechanism of these antioxidant accumulation, especially AsA accumulation in strawberry fruits, remains largely unknown. In this study, we identified FaAKR23 was a regulator of AsA and anthocyanin accumulation. We transiently expressed FaAKR23 in strawberry fruits and conducted metabolic and molecular analyses to explore the role of FaAKR23 in AsA and anthocyanin accumulation. Transient silencing of FaAKR23 (FaAKR23-RNAi)

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Golubkina, N. A., V. A. Zayachkovsky, I. V. Smirnova, et al. "Comparative evaluation of antioxidant characteristics and selenium levels in seeds of Cichorium intybus L. and several representatives of Apiaceae plants." Vegetable crops of Russia, no. 5 (October 14, 2021): 69–74. http://dx.doi.org/10.18619/2072-9146-2021-5-69-74.

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Relevance. Evaluation of nutritional value of seeds of agricultural crops is considered to be highly significant for revealing new sources of antioxidants for humans.Material. The aim of the present investigation was antioxidant status and selenium accumulation levels by chicory seeds (13 cultivars) and comparison of the results with antioxidants status of seeds of other root vegetables: celery (5 cultivars), parsley (2 cultivars), parsnip (3 cultivars) and carrot (7 cultivars).Results. Among agricultural crops studied chicory was characterized by 3-4 higher levels of selenium accumulation by

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3

Gins, M. S., V. K. Gins, P. F. Kononkov, et al. "The effect of low positive temperature on the content of low molecular weight antioxidants in the organs of a vegetable chrysanthemum plant." Rossiiskaia selskokhoziaistvennaia nauka, no. 4 (August 19, 2019): 22–26. http://dx.doi.org/10.31857/s2500-26272019422-26.

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The use of the rapid amperometric method made it possible to promptly measure and evaluate the total content of water- and ethanol-soluble antioxidants in extracts from Chryzantemum coronarium L. plants. The effect of optimal and low positive temperatures on the accumulation of low molecular weight antioxidants: ascorbic acid, phenolic compounds, soluble carbohydrates, carotenoids in various organs of vegetable chrysanthemum plant were investigated. In the leaves of the studied varieties, the content of flavonoids was two times higher than in the stems, while the accumulation level of condense

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Yadav, Jyoti, Anoop K. Verma, Anu Singla, and R. K. Garg. "Metals Toxicity Associated with Oxidative Stress and Altered Level of Antioxidants in the Pathogenesis of Alzheimer’s Disease." Indian Journal of Behavioural Sciences 26, no. 02 (2023): 138–52. http://dx.doi.org/10.55229/ijbs.v26i2.10.

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In this review, metals role in the production of oxidative stress and its association with the altered antioxidant levels have been focused in AD. We have found that metals accumulation is responsible for increased oxidative stress that induces a critical event in the pathogenesis of AD. These pathological changes might alter the antioxidant levels to attenuate free radicals in the body. Some nutritional supplement such as Vitamin E, vitamin C, and vitamin B12 may also have essential roles in the treatment of AD. Alzheimer’s disease is one of the most common forms of dementia in the elderly po

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Carsono, Nono, Sefren Geiner Tumilaar, Dikdik Kurnia, Diding Latipudin, and Mieke Hermiawati Satari. "A Review of Bioactive Compounds and Antioxidant Activity Properties of Piper Species." Molecules 27, no. 19 (2022): 6774. http://dx.doi.org/10.3390/molecules27196774.

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Antioxidants are compounds that are able to inhibit the negative effects that come from free radicals. The phenomenon of imbalanced antioxidant production and the accumulation of free radicals in cells and tissues can cause oxidative stress. Excessive free radicals that enter the body cannot be warded off by endogenous antioxidant compounds so that the required antioxidant compounds can come from the outside, which helps in the performance of endogenous antioxidants. Antioxidants that come from outside consist of synthetic and natural antioxidants; however, synthetic antioxidants are not an op

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Chopra, Mridula, and David I. Thurnham. "Antioxidants and lipoprotein metabolism." Proceedings of the Nutrition Society 58, no. 3 (1999): 663–71. http://dx.doi.org/10.1017/s0029665199000865.

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Lipoprotein metabolism plays a significant role in the pathogenesis of atherosclerosis and risk of vascular disease. Elevated levels of LDL and low levels of HDL are linked to the risk of cardiovascular disease. It is now widely accepted that oxidative modification of LDL affects the metabolism of lipoproteins, leading to their increased accumulation in arterial intima. The present paper will examine some of the accumulating evidence from studies showing relationships between dietary intake of antioxidant nutrients, i.e. vitamins E and C, the carotenoids and the flavonoids, and their influence

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Luo, Maochao, Li Zhou, Zhao Huang, et al. "Antioxidant Therapy in Cancer: Rationale and Progress." Antioxidants 11, no. 6 (2022): 1128. http://dx.doi.org/10.3390/antiox11061128.

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Cancer is characterized by increased oxidative stress, an imbalance between reactive oxygen species (ROS) and antioxidants. Enhanced ROS accumulation, as a result of metabolic disturbances and signaling aberrations, can promote carcinogenesis and malignant progression by inducing gene mutations and activating pro-oncogenic signaling, providing a possible rationale for targeting oxidative stress in cancer treatment. While numerous antioxidants have demonstrated therapeutic potential, their clinical efficacy in cancer remains unproven. Here, we review the rationale for, and recent advances in, p

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Ren, Xinle, Meilin Li, Meixue Zhang, Ruping Zhao, and Cong Han. "Invertase Plays a Vital Role in Regulating Wound-Induced Accumulation of Phenolic Compounds in Carrot Tissue." Horticulturae 10, no. 1 (2024): 72. http://dx.doi.org/10.3390/horticulturae10010072.

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The application of wounding stress can induce the accumulation of phenolic antioxidants in carrots. This study aimed to investigate the possible regulation role of invertase (INV) on the biosynthesis of phenolics in wounded carrots. In this study, carrots were cut into two different wounding intensities of slices and cubes, then stored at 20 °C for 2 days. The results showed that wounding stress caused an obvious increase in phenolic content and antioxidant capacity in carrot tissues, and a positive correlation was observed between the biosynthesis of phenolic compounds and the degradation of

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9

Islamova, F. I., A. M. Musaev, and G. K. Radzhabov. "THE STRUCTURE OF THE VARIABILITY OF SOME AROMATIC PLANTS ON THE CONTENT OF TOTAL ANTIOXIDANTS IN THE ECOLOGICALGEOGRAPHICAL EXPERIMENT." Vegetable crops of Russia, no. 3 (June 14, 2019): 87–90. http://dx.doi.org/10.18619/2072-9146-2019-3-87-90.

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The work presents the results of the study of the antioxidant activity of fruits (clapper seeds) of aromatic plants, (Apiaceae, Lindl.): dill (Anethum graveolens L.) and coriander (Coriandrum sativum L.). The plant materials for determining the total content of antioxidants were collected during an ecological-geographical experiment at the Gunib and Tsudakhar experimental bases of the Mountain Botanical Garden of the Dagestan Scientific Center, Russian Academy of Sciences, at altitudes of 1100 and 1730 meters above sea level, simulating the conditions of mountain-valley and upper mountain clim

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Umar, Shahid, Iram Diva, Naser Anjum, Muhammad Iqbal, Iqbal Ahmad, and Eduarda Pereira. "Potassium-induced alleviation of salinity stress in Brassica campestris L." Open Life Sciences 6, no. 6 (2011): 1054–63. http://dx.doi.org/10.2478/s11535-011-0065-1.

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AbstractSalinity is an important abiotic factor that adversely affects major agricultural soils of the world and hence limits crop productivity. An optimum mineral-nutrient status of plants plays critical role in determining plant tolerance to various stresses. A pot experiment was conducted on mustard (Brassica campestris L.) to study the protective role of added potassium (K, 40 mg kg−1 soil) against salinity-stress (0, 40 and 80 mM NaCl)-induced changes in plant growth, photosynthetic traits, ion accumulation, oxidative stress, enzymatic antioxidants and non-enzymatic antioxidants at 30 day

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Roy, Uttam Kumer, Birthe Vejby Nielsen, and John James Milledge. "Antioxidant Production in Dunaliella." Applied Sciences 11, no. 9 (2021): 3959. http://dx.doi.org/10.3390/app11093959.

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Microalgae have become an attractive natural source of a diverse range of biomolecules, including enzymatic and non-enzymatic antioxidants; nevertheless, economically sustainable production of such compounds from microalgae biomass is still challenging. The main hurdles are: (a) increasing microalgae yield; (b) achieving optimal cultivation conditions; (c) energy-efficient and cost-effective downstream processing (extraction and purification); (d) optimal storage of post-processed antioxidant molecules. This review provides a detailed overview of enzymatic and non-enzymatic antioxidants in the

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Mukundwi, W. T., E. A. Ivanovskaya, and A. V. Ligostaev. "Development of a method for quantitative determination of the hydrophilic antioxidant TF-7 substance by stripping voltammetry." Journal of Siberian Medical Sciences 8, no. 2 (2024): 80–89. http://dx.doi.org/10.31549/2542-1174-2024-8-2-80-89.

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Introduction. Hydrophilic antioxidants are quite attractive for use in biology, veterinary practice and medicine because of their high bioavailability and transport rates, convenience of administration and dosing, suitable for use in infusion therapy in acute conditions. Traditional use of phenolic antioxidants did not presuppose their hydrophilic properties; rather, lipophilicity was preferred. In this regard, it is not surprising that the number of known water-soluble forms of phenolic antioxidants is very limited. Aim. Quantitative determination of the water-soluble antioxidant TF-7 substan

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Li, Ke, Yanfang Ren, Xuejie Dong, Xianyi Ping, and Junyu He. "Tetracycline Alleviates Cadmium Toxicity in Rice Seedlings by Altering Pollutant Accumulation, Nutrient Absorption, Osmoregulation and Antioxidant Metabolism." Molecules 30, no. 10 (2025): 2160. https://doi.org/10.3390/molecules30102160.

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The co-contamination of cadmium (Cd) and tetracycline (TC) in an agricultural environment poses significant risks to plant growth and food safety. This study investigated their combined effects on rice seedlings by analyzing growth parameters, nutrient uptake, photosynthetic pigment levels, antioxidant enzyme activities, nonenzymatic antioxidants, osmoregulatory substances, and secondary metabolites. Results showed that TC alleviated the inhibition of Cd on rice seedling growth by inhibiting Cd accumulation, enhancing nutrient element absorption, facilitating the synthesis of photosynthetic pi

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Andriantsitohaina, Ramaroson, Lucie Duluc, Julio C. García-Rodríguez, et al. "Systems biology of antioxidants." Clinical Science 123, no. 3 (2012): 173–92. http://dx.doi.org/10.1042/cs20110643.

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Understanding the role of oxidative injury will allow for therapy with agents that scavenge ROS (reactive oxygen species) and antioxidants in the management of several diseases related to free radical damage. The majority of free radicals are generated by mitochondria as a consequence of the mitochondrial cycle, whereas free radical accumulation is limited by the action of a variety of antioxidant processes that reside in every cell. In the present review, we provide an overview of the mitochondrial generation of ROS and discuss the role of ROS in the regulation of endothelial and adipocyte fu

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Sangita Roy, Bhanuprakash KS, Sumit Jha, et al. "Aluminum Induced Biochemical Alterations in Amaranthus tricolor." International Journal of Fundamental and Applied Sciences (IJFAS) 2, no. 4 (2013): 54–59. http://dx.doi.org/10.59415/ijfas.v2i4.52.

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Background and Objective : The current study reveals the effect of Aluminum (Al) on Amaranthus tricolor L andsubsequent biochemical changes on the plant. In this study, the effect of Al stress on growth and other related antioxidants andenzymes were investigated. Methodology : This was achieved by investigating plant growth parameters (root/shoot length, dryweight) in presence and absence of various concentrations of Al. The antioxidant activity was determined by estimating proline,ascorbate. The effects of scavenging enzymes were determined by Catalase, Glutathion and SOD activity. The accumu

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Kumar, Vinoth, Malliga Elangovan, and Raja Sekar Srinivasan. "Enzymatic and non-enzymatic antioxidant activity of Pergularia tomentosa against carbon tetra chloride induced hepatic damage in Wistar albino rats." Journal of Microbiology and Biotechnology Research 7, no. 6 (2017): 1. http://dx.doi.org/10.24896/jmbr.2017761.

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Many oxidative stress related disease are due to accumulation of free radicals in the body which causes cell injury. In this study, the enzymatic antioxidants (Superoxide dismutase, Catalase, Glutathione-s-transferase, Glutathione peroxidase, Ascorbate oxidase and Polyphenoloxidase) and non-enzymatic antioxidants (Total reduced glutathione and Vitamin C) activities were determined using Carbon tetrachloride (CCl4) rat liver as experimental model. The ethanol and chloroform extract showed noticeable increases in enzymatic antioxidant and non- enzymatic antioxidant and thus capability to scaveng

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17

Duthie, Garry G. "Determination of activity of antioxidants in human subjects." Proceedings of the Nutrition Society 58, no. 4 (1999): 1015–24. http://dx.doi.org/10.1017/s0029665199001330.

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Evidence from biochemical and animal models suggests that nutritional antioxidants should inhibit the development of diseases such as CHD and certain cancers. This evidence is not clearly corroborated by intervention studies in human subjects, due, in part, to inadequacies in current analytical methodologies. Althoughin vitroassays can give useful information on the attributes required by a compound to act as an antioxidant, results may have little nutritional relevance due to limited bioavailability. The determination of antioxidants in blood is often used as a measure of antioxidant statusin

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Brisseau, GF, AP Dackiw, PY Cheung, N. Christie, and OD Rotstein. "Posttranscriptional regulation of macrophage tissue factor expression by antioxidants." Blood 85, no. 4 (1995): 1025–35. http://dx.doi.org/10.1182/blood.v85.4.1025.bloodjournal8541025.

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Tissue factor (TF) expression by cells of monocyte/macrophage lineage represents an important mechanism underlying the initiation of fibrin deposition at sites of extravascular inflammation. Recent evidence suggests a role for oxidant stress in the signalling pathway of various cell types by virtue of its ability to induce DNA binding of various transcription factors, including nuclear factor kappa B and AP-1. The effect of antioxidant treatment on lipopolysaccharide (LPS)-induced TF expression was examined in murine peritoneal macrophages and human monocytes. Both pyrrolidine dithiocarbamate,

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Yu, Haiyue, Yubin Wang, Jiapeng Xing, et al. "Coronatine Modulated the Generation of Reactive Oxygen Species for Regulating the Water Loss Rate in the Detaching Maize Seedlings." Agriculture 11, no. 7 (2021): 685. http://dx.doi.org/10.3390/agriculture11070685.

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Coronatine (COR), a structural and functional mimic of jasmonates, is involved in a wide array of effects on plant development and defense response. The present study aims to investigate the role of COR, in counteracting drought stress by modulating reactive oxygen species (ROS) homeostasis, water balance, and antioxidant regulation in detached maize plants. Our results showed that COR can markedly decrease the water loss rate, but the antioxidants diphenyleneiodonium chloride (DPI) and dimethylthiourea (DMTU) eliminate the effect of water loss induced by COR. Using the dye 2′,7′-dichlorofluor

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Yakoviichuk, Aleksandr V., Angelica V. Kochubey, Irina Maltseva, Alex Matsyura, Svetlana V. Cherkashina, and Ekaterina A. Lysova. "Biochemical and antioxidant characteristics of the soil strain Chlorococcum oleofaciens (Chlorophyceae, Chlorophyta) grown in light, dark and bicarbonate conditions." Acta Biologica Sibirica 11 (April 5, 2025): 411–47. https://doi.org/10.5281/zenodo.15128676.

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This study aimed to examine the biochemical and antioxidant characteristics of a soil strain of <em>Chlorococcum oleofaciens</em> CAMU MZ–Ch4 (Chlorophyceae, Chlorophyta) when cultured in light, darkness, and a combination of light-bicarbonate and dark-bicarbonate in an acute 96-hour experiment. The study established that cultivation in the dark is accompanied by an increase in the antioxidant status of <em>Chlorococcum oleofaciens</em> CAMU MZ–Ch4 strain cells, which is associated with the accumulation of low-molecular antioxidants and the activation of antioxidant enzymes. Cultur

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Tumilaar, Sefren Geiner, Ari Hardianto, Hirofumi Dohi, and Dikdik Kurnia. "A Comprehensive Review of Free Radicals, Oxidative Stress, and Antioxidants: Overview, Clinical Applications, Global Perspectives, Future Directions, and Mechanisms of Antioxidant Activity of Flavonoid Compounds." Journal of Chemistry 2024 (May 31, 2024): 1–21. http://dx.doi.org/10.1155/2024/5594386.

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Absorption of free radicals in the body cannot be done by antioxidant compounds originating from the human body, so exogenous antioxidants are required to help in their natural antioxidant action. Oxidative stress can be caused by an imbalance of free radical inhibitors and the accumulation of free radicals that enter cellular structures. Synthetic antioxidants found in external antioxidants are not the primary choice because they are harmful and carcinogenic. Therefore, using natural ingredients provides a necessary alternative to constructing novel natural antioxidants. Recent studies have

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Liu, Ping, Yixuan Li, Ran Wang, Fazheng Ren, and Xiaoyu Wang. "Oxidative Stress and Antioxidant Nanotherapeutic Approaches for Inflammatory Bowel Disease." Biomedicines 10, no. 1 (2021): 85. http://dx.doi.org/10.3390/biomedicines10010085.

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Oxidative stress, caused by the accumulation of reactive species, is associated with the initiation and progress of inflammatory bowel disease (IBD). The investigation of antioxidants to target overexpressed reactive species and modulate oxidant stress pathways becomes an important therapeutic option. Nowadays, antioxidative nanotechnology has emerged as a novel strategy. The nanocarriers have shown many advantages in comparison with conventional antioxidants, owing to their on-site accumulation, stability of antioxidants, and most importantly, intrinsic multiple reactive species scavenging or

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Maslennikov, Pavel, Elena Golovina, and Anastasia Artemenko. "Ecological and Geochemical Conditions for the Accumulation of Antioxidants in the Leaves of Lathyrus maritimus (L.) Bigel." Plants 9, no. 6 (2020): 746. http://dx.doi.org/10.3390/plants9060746.

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The article explores how location affected the dynamics of accumulation of ascorbic acid (AC) and oxidized forms of AC—dehydroascorbic acid (DAA) and diketogulonic acid (DKGA) in beach pea during ontogenetic development. Our analysis focuses on research of the ecological and geochemical conditions growing of the plant on the Curonian Spit. The level of hydrogen peroxide and the activity of enzymes that break it down were analyzed. Antioxidant activity and the total concentration of phenolics were evaluated in the leaves of beach pea on the leeward and windward sides of the foredune. It was est

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Mokrosnop, V. M., та E. K. Zolotareva. "ACCUMULATION OF α-TOCOPHEROL IN MICROALGAE CELLS". Microbiology&Biotechnology, № 2(52) (29 вересня 2021): 6–26. http://dx.doi.org/10.18524/2307-4663.2021.2(52).223991.

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To date, the main natural source of vitamin E is vegetable oils. Among the compounds of the vitamin E group, α-tocopherol has the higher biological activity, the relative content of which in vegetable oils is comparatively small. Significantly higher concentrations of α-tocopherol (up to 4-6 mg / g dry weight) accumulate some microalgae, such as Euglena gracilis, Dunaliella tertiolecta, Nannochloropsis oculata, Tetraselmis suecica and others. Due to this, there has been a growing interest in biotechnology of microalgae as a raw material for the production of vitamins. The largest amount of toc

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Yoon, Hyo In, Wenjuan Zhang, and Jung Eek Son. "Optimal Duration of Drought Stress Near Harvest for Promoting Bioactive Compounds and Antioxidant Capacity in Kale with or without UV-B Radiation in Plant Factories." Plants 9, no. 3 (2020): 295. http://dx.doi.org/10.3390/plants9030295.

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Among abiotic stresses, both drought and UV-B radiation effectively trigger the accumulation of secondary metabolites, and can be widely applied in plant factories. The objectives of this study were to investigate antioxidant accumulation under drought stress alone, or in combination with UV-B radiation near harvest, and to determine an optimal treatment time for maximum antioxidant production. Kale (Brassica oleracea L. var. acephala) plants were grown in a plant factory and harvested at 42 days after transplanting. The single and combination treatments lasted for 7 to 1 days and 4 to 2 days

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Amara, Flavio, Miluscia Berbenni, Martina Fragni, et al. "Neuroprotection by Cocktails of Dietary Antioxidants under Conditions of Nerve Growth Factor Deprivation." Oxidative Medicine and Cellular Longevity 2015 (2015): 1–15. http://dx.doi.org/10.1155/2015/217258.

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Dietary antioxidants may be useful in counteracting the chronic inflammatory status in neurodegenerative diseases by reducing oxidative stress due to accumulation of reactive oxygen species (ROS). In this study, we newly described the efficacy of a number of dietary antioxidants (polyphenols, carotenoids, thiolic compounds, and oligoelements) on viability of neuronal PC12 cells following Nerve Growth Factor (NGF) deprivation, a model of age-related decrease of neurotrophic support that triggers neuronal loss. Neuroprotection by antioxidants during NGF deprivation for 24 h was largely dependent

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Roy, Proshanta, Daniele Tomassoni, Enea Traini, et al. "Natural Antioxidant Application on Fat Accumulation: Preclinical Evidence." Antioxidants 10, no. 6 (2021): 858. http://dx.doi.org/10.3390/antiox10060858.

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Obesity represents one of the most important challenges in the contemporary world that must be overcome. Different pathological consequences of these physical conditions have been studied for more than 30 years. The most nagging effects were found early in the cardiovascular system. However, later, its negative impact was also investigated in several other organs. Damage at cellular structures due to overexpression of reactive oxygen species together with mechanisms that cause under-production of antioxidants leads to the development of obesity-related complications. In this view, the negative

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Golubkina, N. A., I. S. Sarkina, V. A. Lapchenko, E. V. Lapchenko, N. A. Bagrikova, and T. S. Naumenko. "Antioxidant status and selenium content in macromycetes of the Mountainous Crimea." Bulletin of the State Nikitsky Botanical Gardens, no. 141 (January 20, 2022): 71–80. http://dx.doi.org/10.36305/0513-1634-2021-141-71-80.

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Antioxidant status and selenium accumulation by 18 macromycetes species of the Mountainous Crimea was investigated. Total antioxidant activity of 5 families’ representatives composed ranges of 23.9 - 43.3 mg GAE/g d.w. for Boletaceae, 13.0-25.0 mg GAE/g d.w. for Russulaceae, 13.5-20.9 mg GAE/g d.w. for Tricholomotaceae, 13.8-38.0 mg GAE/g d.w. for Agaricaceae. Selenium accumulation levels reached 423-3352 µg/kg d.w. (Boletaceae), 236-1076 µg/kg d.w. (Russulaceae), 664-1213 µg/kg d.w (Tricholomotaceae) and 289-2392 µg/kg d.w. (Agaricaceae). High antioxidant activity (39.2 mg GAE/g d.w.) and spe

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Yang, Jung-Pyo, Ji-Hun Shin, Seung-Hwan Seo, Sang-Gyun Kim, Sang Lee, and Eun-Hee Shin. "Effects of Antioxidants in Reducing Accumulation of Fat in Hepatocyte." International Journal of Molecular Sciences 19, no. 9 (2018): 2563. http://dx.doi.org/10.3390/ijms19092563.

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The progress of the hepatic steatosis (HS), a clinicopathological status, is influenced by cellular oxidative stress, lipogenesis, fatty acid (FA) oxidation, and inflammatory responses. Because antioxidants are gaining attention as potent preventive agents for HS, we aimed to investigate anti-lipogenic effects of the antioxidants vitamin C (VC), N-acetylcysteine (NAC), and astaxanthin (ATX) using hepatocytes. For this, we established an in vitro model using 1 mM oleic acid (OA) and human liver hepatocellular carcinoma (HepG2) cells; 10 μM antioxidants were evaluated for their ability to reduce

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Sergiev, Iskren Georgiev, Desislava Aleksandrova Todorova, Valentina Karlovna Gins, Svetlana Mikhailovna Motyleva, Ekaterina Muratovna Gins, and Evgeny Aleksandrovich Moskalev. "Nutritional value of vegetable Amaranthus tricolor L. seedlings grown in Moscow region." RUDN Journal of Agronomy and Animal Industries 14, no. 3 (2019): 225–38. http://dx.doi.org/10.22363/2312-797x-2019-14-3-225-238.

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The use of amperometric express method made it possible to measure quickly and evaluate content of waterand alcohol-soluble antioxidants in extracts from Amaranthus tricolor L. plants. Accumulation of low molecular weight antioxidants: ascorbic acid, beta-cyanine (amaranthine) and the total content of antioxidants in various organs of Valentina amaranth seedlings were studied. The maximum amount of low molecular weight antioxidants accumulates in leaves, compared with roots and stems of seedlings grown in open and protected ground. In open ground conditions, amaranth leaves and stems have 1.5-

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Pham, Linh, Vinh Phuc Dang, Peter Cao, and Trung Vo. "Thermal Stress Enhances Phenolic Metabolism and Antioxidant Capacity in Hamatococcus pluvialis: A Sustainable Platform for Microalgal Antioxidants." Journal of Biology and Nature 17, no. 2 (2025): 121–30. https://doi.org/10.56557/joban/2025/v17i29503.

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Haematococcus pluvialis is a commercially valuable freshwater green microalga with the remarkable ability to produce abundant natural astaxanthin, a potent natural antioxidant with applications in nutraceuticals and cosmetics. Adverse cultivation conditions significantly affect the accumulation of phenolic compounds and antioxidant capacity in this microalga. In this study, the effects of three temperature treatments (10°C, 25°C, and 35°C) on antioxidant compounds accumulation in H. pluvialis were investigated using two culture media: BG11 and OHM. At 35°C, phenolic content per cell (0.104 ± 0

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Großkinsky, Dominik K., Barbara E. Koffler, Thomas Roitsch, Romana Maier, and Bernd Zechmann. "Compartment-Specific Antioxidative Defense in Arabidopsis Against Virulent and Avirulent Pseudomonas syringae." Phytopathology® 102, no. 7 (2012): 662–73. http://dx.doi.org/10.1094/phyto-02-12-0022-r.

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The accumulation of reactive oxygen species (ROS) during biotic stress is either part of a hypersensitive response of the plant or induced directly by the pathogen. Antioxidants such as ascorbate and glutathione counteract the accumulation of ROS and are part of the defense reaction. The aim of the present study was to investigate the compartment-specific importance of ascorbate and glutathione during a virulent and avirulent Pseudomonas syringae infection in Arabidopsis thaliana. Peroxisomes were found to be the hotspot for glutathione accumulation reaching 452% and 258% of control levels 24

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Noguera, Jose Carlos. "Interacting effects of early dietary conditions and reproductive effort on the oxidative costs of reproduction." PeerJ 5 (March 14, 2017): e3094. http://dx.doi.org/10.7717/peerj.3094.

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The hypothesis that oxidative damage accumulation can mediate the trade-off between reproduction and lifespan has recently been questioned. However, in captive conditions, studies reporting no evidence in support of this hypothesis have usually provided easy access to food which may have mitigated the cost of reproduction. Here, I test the hypothesis that greater investment in reproduction should lead to oxidative damage accumulation and telomere loss in domestic zebra finchesTaeniopygia guttata. Moreover, since the change or fluctuation in diet composition between early and late postnatal per

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Gulnara, Badridze, Chkhubianishvili Eva, Rapava Luara, Kikvidze Medea, Chigladze Lali, and Tsilosani Ketevan. "Study of Antioxidants in Leaves of Xerophytes of Georgia." International Journal of Environmental & Agriculture Research 9, no. 2 (2023): 17–23. https://doi.org/10.5281/zenodo.7685038.

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<strong>Abstract</strong><strong>—</strong> Climate warming may appear fatal for many plant species. Thanks to evolutionary formed mechanisms of resistance xerophytes possess high ability of adaptation to elevated temperature and water deficiency. That is why the knowledge of biology of drought resistant species seems very important for possible recovering of deserted regions in future. Antioxidant system is regarded to play an essential role in plant resistance against water deficiency. On the base of analysis of antioxidant system, stress-adaptation strategies of xerophytes, growing at

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Liakopoulos, Vassilios, Stefanos Roumeliotis, Xenia Gorny, Evangelia Dounousi, and Peter R. Mertens. "Oxidative Stress in Hemodialysis Patients: A Review of the Literature." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–22. http://dx.doi.org/10.1155/2017/3081856.

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Hemodialysis (HD) patients are at high risk for all-cause mortality and cardiovascular events. In addition to traditional risk factors, excessive oxidative stress (OS) and chronic inflammation emerge as novel and major contributors to accelerated atherosclerosis and elevated mortality. OS is defined as the imbalance between antioxidant defense mechanisms and oxidant products, the latter overwhelming the former. OS appears in early stages of chronic kidney disease (CKD), advances along with worsening of renal failure, and is further exacerbated by the HD process per se. HD patients manifest exc

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Hao, Juan, Panpan Lou, Yidie Han, et al. "Ultraviolet-B Irradiation Increases Antioxidant Capacity of Pakchoi (Brassica rapa L.) by Inducing Flavonoid Biosynthesis." Plants 11, no. 6 (2022): 766. http://dx.doi.org/10.3390/plants11060766.

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As an important abiotic stress factor, ultraviolet-B (UV-B) light can stimulate the accumulation of antioxidants in plants. In this study, the possibility of enhancing antioxidant capacity in pakchoi (Brassica rapa L.) by UV-B supplementation was assessed. Irradiation with 4 µmol·m−2·s−1 UV-B for 4 h or 2 µmol·m−2·s−1 UV-B for 24 h significantly increased the 1,1–diphenyl–2–picrylhydrazyl (DPPH) scavenging activity and total reductive capacity, as a result of inducing a greater accumulation of total polyphenols and flavonoids without affecting the plant biomass. A high performance liquid chrom

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Fu, Minghao, Kyung-Sik Yoon, Joohun Ha, Insug Kang, and Wonchae Choe. "Crosstalk Between Antioxidants and Adipogenesis: Mechanistic Pathways and Their Roles in Metabolic Health." Antioxidants 14, no. 2 (2025): 203. https://doi.org/10.3390/antiox14020203.

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The interplay between oxidative stress and adipogenesis is a critical factor in the development of obesity and its associated metabolic disorders. Excessive reactive oxygen species (ROS) disrupt key transcription factors such as peroxisome proliferator-activated receptor gamma (PPARγ) and CCAAT/enhancer-binding protein alpha (C/EBPα), impairing lipid metabolism, promoting adipocyte dysfunction, and exacerbating inflammation and insulin resistance. Antioxidants, classified as endogenous (e.g., glutathione, superoxide dismutase, and catalase) and exogenous (e.g., polyphenols, flavonoids, and vit

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Islamova, F. I., G. K. Radzhabov, S. V. Goriainov, F. Hajjar, and A. M. Aliev. "Composition of fatty acids, phytosterols and total content of antioxidants of Morus L. seeds." Известия Российской академии наук. Серия биологическая, no. 1 (May 24, 2024): 143–50. http://dx.doi.org/10.31857/s1026347024010144.

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This paper presents for the first time the results of studying the total content of antioxidants in the seeds of Morus L. The composition of fatty and steric acids of the seeds of mulberry fruits Morus L. was also studied: polymorphic speciesMorus alba(white-fruited, pink-fruited, black-fruited) andMorus nigra(Khartut variety). As a result of the studies, 12 fatty acids were identified. The main ones were linoleic acid, palmitic oleic acid, and stearic acid. The predominant fatty acid in all samples was linoleic, which varied from 67.5 to 79.0%. 15 sterols were found, among whichβ-Sitosterol a

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Suárez-Carrillo, Alejandra, Mónica Álvarez-Córdoba, Ana Romero-González, et al. "Antioxidants Prevent Iron Accumulation and Lipid Peroxidation, but Do Not Correct Autophagy Dysfunction or Mitochondrial Bioenergetics in Cellular Models of BPAN." International Journal of Molecular Sciences 24, no. 19 (2023): 14576. http://dx.doi.org/10.3390/ijms241914576.

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Neurodegeneration with brain iron accumulation (NBIA) is a group of rare neurogenetic disorders frequently associated with iron accumulation in the basal nuclei of the brain. Among NBIA subtypes, β-propeller protein-associated neurodegeneration (BPAN) is associated with mutations in the autophagy gene WDR45. The aim of this study was to demonstrate the autophagic defects and secondary pathological consequences in cellular models derived from two patients harboring WDR45 mutations. Both protein and mRNA expression levels of WDR45 were decreased in patient-derived fibroblasts. In addition, the i

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Passone, M., M. Doprado, and M. Etcheverry. "Food-grade antioxidants for control of Aspergillus section Flavi and interrelated mycoflora of stored peanuts with different water activities." World Mycotoxin Journal 2, no. 4 (2009): 399–407. http://dx.doi.org/10.3920/wmj2008.1110.

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The inhibitory effect of butylated hydroxyanisole (BHA) and butylated hydroxytoluene (BHT) mixture on fungal populations, Aspergillus section Flavi and aflatoxins accumulation in in-pod peanuts during storage in big bags was investigated. In-pod peanuts were previously conditioned at different water activities (0.94, 0.88, 0.84 and 0.76 aw) and treated with food-grade antioxidants. Both control and treated peanuts were stored for 6 months and sampled at monthly intervals. BHA-BHT mixture reduced the incidence of peanut fungal populations between 0.6-20.4% and between 1.2-33.1% during 1-3 and 4

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Ismail, Hebatollah, Jelena Dragišic Maksimovic, Vuk Maksimovic, et al. "Rutin, a flavonoid with antioxidant activity, improves plant salinity tolerance by regulating K+ retention and Na+ exclusion from leaf mesophyll in quinoa and broad beans." Functional Plant Biology 43, no. 1 (2016): 75. http://dx.doi.org/10.1071/fp15312.

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The causal relationship between salinity and oxidative stress tolerance is well established, but specific downstream targets and the role of specific antioxidant compounds in controlling cellular ionic homeostasis remains elusive. In this work, we have compared antioxidant profiles of leaves of two quinoa genotypes contrasting in their salt tolerance, with the aim of understanding the role of enzymatic and non-enzymatic antioxidants in salinity stress tolerance. Only changes in superoxide dismutase activity were correlated with plant adaptive responses to salinity. Proline accumulation played

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B. Wegener, Christina, Gisela Jansen, and Hans-Ulrich Jürgens. "Bioactive compounds in potatoes: Accumulation under drought stress conditions." Functional Foods in Health and Disease 5, no. 3 (2015): 108. http://dx.doi.org/10.31989/ffhd.v5i3.175.

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Background: Potato (Solanum tuberosum) is a valuable source of bioactive compounds. Besides starch, crude fibre, amino acids (AAS), vitamins and minerals, the tubers contain diverse phenolic compounds. These phenolics and AAS confer anti-oxidant protection against reactive oxygen species, tissue damage, and diseases like atherosclerosis, renal failure, diabetes mellitus, and cancer. Climate change and drought stress may become a major risk for crop production worldwide, resulting in reduced access for those who depend on the nutritional value of this staple crop.Objective: The aim of this stud

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Bhandari, Shiva Ram, and Jun Gu Lee. "Ripening-Dependent Changes in Antioxidants, Color Attributes, and Antioxidant Activity of Seven Tomato (Solanum lycopersicumL.) Cultivars." Journal of Analytical Methods in Chemistry 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/5498618.

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To evaluate the ripening-dependent changes in phytonutrients, seven commercial cultivars (two general and five cherry) of tomatoes were cultivated under greenhouse conditions. Fruits were harvested at breaker, turning, pink, light red, and red stages of each cultivar, and antioxidant contents, color attributes, and antioxidant activities were measured. During ripening process, lycopene content increased from the breaker to red stage, while lutein displayed the reverse accumulation pattern, with higher values during the breaker stage. In contrast,β-carotene showed the highest levels of synthesi

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Rtibi, Ka�s, Mohamed Amri, Hichem Sebai, and Lamjed Marzouki. "Implication of Oxidative Stress in Small Intestine Disorders, Constipation and Diarrhea: A Mini Review." Recent Advances in Biology and Medicine 03 (2017): 66. http://dx.doi.org/10.18639/rabm.2017.03.457021.

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Diarrhea pathophysiology and constipation are multifactorial gastrointestinal (GI) disorders characterized by intestinal peristalsis disruption of and an irregularity in secretion/absorption process. Oxidative stress, as an imbalance in prooxidants/antioxidants, has recently been recognized as a significant player in these GI disturbances. In this respect, numerous studies were performed and have shown that the deleterious effects on GI tract were accompanied by accumulation of oxidants and depletion of antioxidant system. Antioxidant remedy is necessary in scavenging free radicals and reactiv

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Efimova, Marina V., Elena D. Danilova, Ilya E. Zlobin, et al. "Priming Potato Plants with Melatonin Protects Stolon Formation under Delayed Salt Stress by Maintaining the Photochemical Function of Photosystem II, Ionic Homeostasis and Activating the Antioxidant System." International Journal of Molecular Sciences 24, no. 7 (2023): 6134. http://dx.doi.org/10.3390/ijms24076134.

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Melatonin is among one of the promising agents able to protect agricultural plants from the adverse action of different stressors, including salinity. We aimed to investigate the effects of melatonin priming (0.1, 1.0 and 10 µM) on salt-stressed potato plants (125 mM NaCl), by studying the growth parameters, photochemical activity of photosystem II, water status, ion content and antioxidant system activity. Melatonin as a pleiotropic signaling molecule was found to decrease the negative effect of salt stress on stolon formation, tissue water content and ion status without a significant effect

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Castro-Cegrí, Alejandro, Sandra Sierra, Laura Hidalgo-Santiago, et al. "Postharvest Treatment with Abscisic Acid Alleviates Chilling Injury in Zucchini Fruit by Regulating Phenolic Metabolism and Non-Enzymatic Antioxidant System." Antioxidants 12, no. 1 (2023): 211. http://dx.doi.org/10.3390/antiox12010211.

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Reports show that phytohormone abscisic acid (ABA) is involved in reducing zucchini postharvest chilling injury. During the storage of harvested fruit at low temperatures, chilling injury symptoms were associated with cell damage through the production of reactive oxygen species. In this work, we have studied the importance of different non-enzymatic antioxidants on tolerance to cold stress in zucchini fruit treated with ABA. The application of ABA increases the antioxidant capacity of zucchini fruit during storage through the accumulation of ascorbate, carotenoids and polyphenolic compounds.

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Attia, Mohamed, Ebtessam Ahmed Essa, Randa Mohammed Zaki, and Amal Ali Elkordy. "An Overview of the Antioxidant Effects of Ascorbic Acid and Alpha Lipoic Acid (in Liposomal Forms) as Adjuvant in Cancer Treatment." Antioxidants 9, no. 5 (2020): 359. http://dx.doi.org/10.3390/antiox9050359.

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Antioxidants are known to minimize oxidative stress by interacting with free radicals produced as a result of cell aerobic reactions. Oxidative stress has long been linked to many diseases, especially tumours. Therefore, antioxidants play a crucial role in the prevention or management of free radical-related diseases. However, most of these antioxidants have anticancer effects only if taken in large doses. Others show inadequate bioavailability due to their instability in the blood or having a hydrophilic nature that limits their permeation through the cell membrane. Therefore, entrapping anti

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Tam, Eddie, Hye Kyoung Sung, Nhat Hung Lam, et al. "Role of Mitochondrial Iron Overload in Mediating Cell Death in H9c2 Cells." Cells 12, no. 1 (2022): 118. http://dx.doi.org/10.3390/cells12010118.

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Iron overload (IO) is associated with cardiovascular diseases, including heart failure. Our study’s aim was to examine the mechanism by which IO triggers cell death in H9c2 cells. IO caused accumulation of intracellular and mitochondrial iron as shown by the use of iron-binding fluorescent reporters, FerroOrange and MitoFerroFluor. Expression of cytosolic and mitochondrial isoforms of Ferritin was also induced by IO. IO-induced iron accumulation and cellular ROS was rapid and temporally linked. ROS accumulation was detected in the cytosol and mitochondrial compartments with CellROX, DCF-DA and

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KHAN, Imran, Mahmoud F. SELEIMAN, Muhammad U. CHATTHA, et al. "Enhancing antioxidant defense system of mung bean with a salicylic acid exogenous application to mitigate cadmium toxicity." Notulae Botanicae Horti Agrobotanici Cluj-Napoca 49, no. 2 (2021): 12303. http://dx.doi.org/10.15835/nbha49212303.

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Cadmium (Cd) accumulation is an emerging environmental hazard and has detrimental effects on plant growth and development. Salicylic acid (SA) is a well-known plant growth regulator that can initiate various molecular pathways to ameliorate Cd toxicity. The experiment was executed to scrutinize the mediatory role of SA to accelerate the defensive mechanism of mung bean in response to Cd stress. Mung bean plants were exposed to 0, 5, 10 and 15 mg Cd kg-1 of soil. Exogenous application of SA 0, 10-6 and 10-3 M was added prior flowering. Results exhibited that Cd stress considerably reduced the g

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Yeo, Hyeon Ji, Soo-Yeon Lim, Chang Ha Park, et al. "Metabolic Analyses and Evaluation of Antioxidant Activity in Purple Kohlrabi Sprouts after Exposed to UVB Radiation." Antioxidants 11, no. 8 (2022): 1443. http://dx.doi.org/10.3390/antiox11081443.

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Various metabolites act as plant defense molecules due to their antioxidant abilities. This study aimed to investigate the influence of UVB irradiation on the accumulation of metabolites, including primary metabolites (sugar, sugar alcohols, amino acids, organic acids, and an amine) and secondary metabolites (anthocyanins, fatty acids, and phenolic acids), and its synergistic antioxidant ability, in purple kohlrabi sprouts. Metabolite analyses revealed a total of 92 metabolites in the sprouts. Specifically, the levels of most amino acids increased after 24 h of UVB treatment, and then slightly

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