Academic literature on the topic 'Acetaminophen'

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Journal articles on the topic "Acetaminophen"

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Myers, Wade C., Terrance A. Otto, Elaine Harris, Daniel Diaco, and Anthony Moreno. "ACETAMINOPHEN OVERDOSE AS A SUICIDAL GESTURE: A SURVEY OF ADOLESCENTS' KNOWLEDGE OF ITS POTENTIAL FOR TOXICITY." Pediatrics 93, no. 6 (1994): A36. http://dx.doi.org/10.1542/peds.93.6.a36.

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Acetaminophen is a popular nonprescription analgesic that is often taken in overdose by adolescents during suicidal gestures. The authors hypothesized that most adolescents are naive about the toxic and lethal potential of acetaminophen in overdose. A one-page, 12-item questionnaire was administered to 169 high school students to evaluate their perceptions and knowledge in this area. Whereas only 22% of the sample underestimated the dose of acetaminophen necessary to cause harm, 40.5% underestimated the potential lethality of acetaminophen in overdose. Moreover, 17% of the sample did not belie
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S.T., Schultz. "Can autism be triggered by acetaminophen activation of the endocannabinoid system?" Acta Neurobiologiae Experimentalis 70, no. 2 (2010): 227–31. http://dx.doi.org/10.55782/ane-2010-1793.

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Acetaminophen use in children has been associated with increased autism risk. Recent evidence suggests that acetaminophen's analgesic actions result from activation of the endocannabinoid system, and activation of this system can have neuromodulatory consequences during development. This investigation was performed to determine if there is evidence to support the hypothesis that acetaminophen use can trigger autism by activation of the endocannabinoid system.
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Thibault, Céline, Élaine Pelletier, Christina Nguyen, et al. "The Three W's of Acetaminophen In Children: Who, Why, and Which Administration Mode?" Journal of Pediatric Pharmacology and Therapeutics 28, no. 1 (2023): 20–28. http://dx.doi.org/10.5863/1551-6776-28.1.20.

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Acetaminophen is one of the oldest medications commonly administered in children. Its efficacy in treating fever and pain is well accepted among clinicians. However, the available evidence supporting the use of acetaminophen's different modes of administration remains relatively scarce and poorly known. This short report summarizes the available evidence and provides a framework to guide clinicians regarding a rational use of acetaminophen in children.
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Keaveney, Alexis, Ellen Peters, and Baldwin Way. "Effects of acetaminophen on risk taking." Social Cognitive and Affective Neuroscience 15, no. 7 (2020): 725–32. http://dx.doi.org/10.1093/scan/nsaa108.

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Abstract Acetaminophen, an analgesic and antipyretic available over-the-counter and used in over 600 medicines, is one of the most consumed drugs in the USA. Recent research has suggested that acetaminophen’s effects extend to the blunting of negative as well as positive affect. Because affect is a determinant of risk perception and risk taking, we tested the hypothesis that acute acetaminophen consumption (1000 mg) could influence these important judgments and decisions. In three double-blind, placebo-controlled studies, healthy young adults completed a laboratory measure of risk taking (Ball
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Harris, Hope Elaine, and Wade C. Myers. "Adolescents' Misperceptions of the Dangerousness of Acetaminophen in Overdose." Suicide and Life-Threatening Behavior 27, no. 3 (1997): 274–77. http://dx.doi.org/10.1111/j.1943-278x.1997.tb00409.x.

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Clinical observations suggest that adolescents commonly and naively use acetaminophen in suicide attempts even when they do not wish to die. It is estimated that 18 500‐mg acetaminophen tablets can lead to hepatotoxicity, while death is usually associated with ingestion of 50 or more tablets. A sample comprising 569 adolescent students completed an author‐designed survey assessing teenagers' knowledge of acetaminophen's therapeutic and harmful effects. The findings support our original data that adolescents have ready access to acetaminophen and use it in suicide attempts, but underestimate it
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Sahara, Mia Putri, Siska Julia Cindy Winangsih, Siti Jaisy Millah Hadaina, Komang Pranayoga Prandhana Putra, Rizqi Al Kasiron, and Catarina Budyono. "Tatalaksana Non-Acetaminophen Induced Acute Liver Failure Dengan Menggunakan Nacetylcysteine." Unram Medical Journal 11, no. 4 (2022): 1183–86. http://dx.doi.org/10.29303/jk.v11i4.4750.

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Gagal hati akut merupakan suatu kondisi dimana terjadi disfungsi hati yang bersifat akut. Terdapat dua jenis dari gagal hati akut ini yaitu acetaminophen induced acute liver failure dan non acetaminophen induced acute liver failure.Gagal hati akut memiliki penilaian angka insidensi sebanyak 1-6 kasus per 1 juta orang setiap tahunnya pada berbagai negara maju, sedangkan untuk Negara berkembang penilaian angka insidensi diperkiraan lebih besar karena memiliki angka insidensi hepatitis yang tinggi, di Amerika, diperkirakan sebanyak 2500 kasus gagal hati akut per tahunnya. Sampai saat ini, tidak a
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Sahara, Mia Putri. "Tatalaksana Non-Acetaminophen Induced Acute Liver Failure Dengan Menggunakan N-acetylcysteine." Unram Medical Journal 11, no. 4 (2022): 1183–86. http://dx.doi.org/10.29303/jku.v11i4.801.

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Gagal hati akut merupakan suatu kondisi dimana terjadi disfungsi hati yang akut. Terdapat dua jenis akut dari gagal hati akut ini yaitu acetaminophen induced acute liver failure dan non acetaminophen induced acute liver failure.Gagal hati memiliki penilaian angka insidensi sebanyak 1-6 kasus per 1 juta setiap tahun pada berbagai negara maju, sedangkan untuk Negara berkembang angka insidensi diperkiraan lebih besar karena memiliki angka insidensi hepatitis yang tinggi, di Amerika, diperkirakan sebanyak 2.500 kasus gagal hati akut per tahun. Sampai saat ini, tidak ada pengobatan yang mampu untuk
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Osahon Stanley Usiobeigbe, Kingsley O. Airhomwanbor, Lucky Eromosele Omolumen, Raphael O. Ikyaagba, Ernest Asibor, and Daniella Damilola Ogunsina. "Effects of Garnoderma lucidum on Acetaminophen-Induced Liver Injury in Wistar Rats." World Journal of Advanced Research and Reviews 21, no. 3 (2024): 2599–608. http://dx.doi.org/10.30574/wjarr.2024.21.3.0977.

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Introduction: Ganoderma lucidum is considered to be a medicinal mushroom, widely used to prevent or treat different types of diseases including cancer, cardiovascular disease and hepatic dysfunction. This study aimed to evaluate the effect of Ganoderma lucidum on acetaminophen-induced liver injury in wistar rats. Methods: Forty (40) male wistar rats were used for this study. Hepatoxicity was induced by oral administration of acetaminophenn (3000 mg/kg of body weight) for the last 21 consecutive days of the dietary of regimen Ganoderma lucidum. These rats were divided into eight cages each cont
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Osahon, Stanley Usiobeigbe, O. Airhomwanbor Kingsley, Eromosele Omolumen Lucky, O. Ikyaagba Raphael, Asibor Ernest, and Damilola Ogunsina Daniella. "Effects of Garnoderma lucidum on Acetaminophen-Induced Liver Injury in Wistar Rats." World Journal of Advanced Research and Reviews 21, no. 3 (2024): 2599–608. https://doi.org/10.5281/zenodo.14182157.

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<strong>Introduction:&nbsp;</strong><em>Ganoderma lucidum</em>&nbsp;is considered to be a medicinal mushroom, widely used to prevent or treat different types of diseases including cancer, cardiovascular disease and hepatic dysfunction. This study aimed to evaluate the effect of&nbsp;<em>Ganoderma</em>&nbsp;<em>lucidum</em>&nbsp;on acetaminophen-induced liver injury in wistar rats. <strong>Methods</strong>: Forty (40) male wistar rats were used for this study. Hepatoxicity was induced by oral administration of acetaminophenn (3000 mg/kg of body weight) for the last 21 consecutive days of the di
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Iqbal, Sohail, Rao Salman Aziz, Liaquat Ali, et al. "ACETAMINOPHEN." Professional Medical Journal 25, no. 12 (2018): 1923–27. http://dx.doi.org/10.29309/tpmj/18.4807.

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Introduction: Nephrotoxicity is an important side effect of many medicine and chemotherapeutic agents. Active ingredients from natural sources have shown promising results to alleviate these side effects. Objectives: We aimed to investigate the effects of aqueous Date fruit extract in animal model of paracetamol induced nephrotoxicity in rats. Study Design: Experimental. Setting: Sargodha Institute of Health Sciences Sargodha. Period: January 2017-September 2017. Material &amp; Methods: 30 rats were randomly divided into five groups treatment groups. Treatments were given daily for two weeks.
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Dissertations / Theses on the topic "Acetaminophen"

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Nam, Haemi. "Acetaminophen, Aggression, and Learning: An Investigation of Acetaminophen's Social Side Effects." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1557155429796022.

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Poon, Yuk-king Karen. "The antagonistic effect of paracetamol on ethanol-induced gastric damage in rats /." [Hong Kong] : University of Hong Kong, 1989. http://sunzi.lib.hku.hk/hkuto/record.jsp?B12718592.

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Soliman, Gamal. "A study of acetaminophen analogues' toxicity." Thesis, University of Ottawa (Canada), 1985. http://hdl.handle.net/10393/4926.

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Reddyhoff, Dennis. "Mathematical modelling of acetaminophen induced hepatotoxicity." Thesis, Loughborough University, 2016. https://dspace.lboro.ac.uk/2134/23008.

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Acetaminophen, known as paracetamol in the UK and Tylenol in the United States, is a widespread and commonly used painkiller all over the world. Taken in large enough doses, however, it can cause fatal liver damage. In the U.S., 56000 people are admitted to hospital each year due to acetaminophen overdose and its related effects, at great cost to healthcare services. In this thesis we present a number of different models of acetaminophen metabolism and toxicity. Previously, models of acetaminophen toxicity have been complex and due to this complexity, do not lend themselves well to more advanc
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Mischkowski, Dominik. "The Social Side Effects of Acetaminophen." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1438081282.

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Bashir, Shazma. "Mechanism of Paracetamol (acetaminophen) induced hypothermia." Thesis, University of East London, 2018. http://roar.uel.ac.uk/7308/.

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Paracetamol is a potent analgesic and antipyretic with limited side effects compared to the nonsteroidal anti-inflammatory drugs (NSAIDs) and opiates. Worldwide paracetamol is commonly used to treat pain and fever in both children and adults. Although, this drug has been in clinical use for more than a century, the mechanisms of action are not fully understood. Historically some of the actions of paracetamol were attributed to the inhibition of central cyclooxygenase (COX-1 and COX-2) enzymes however given the weak inhibitory effects on COX-1 and COX-2 enzymes, alternative targets have been su
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Xu, Zheng. "Developmental Toxicity of Dextromethorphan and Acetaminophen in Zebrafish Embryos/Larvae: Relevance of SULT-mediated Dextromethorphan/Acetaminophen Sulfation." Toledo, Ohio : University of Toledo, 2010. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=toledo1271433014.

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Thesis (M.S.)--University of Toledo, 2010.<br>Typescript. "Submitted to the Graduate Faculty as a partial fulfillment of the requirement for the Master of Science in Pharmacology and Toxicology." "A thesis entitled"--at head of title. Title from title page of PDF document. Bibliography: p. 68-81.
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Harnagea, Theophilus Eugenia. "Acetaminophen stimulates proliferation of breast cancer cells." Morgantown, W. Va. : [West Virginia University Libraries], 1999. http://etd.wvu.edu/templates/showETD.cfm?recnum=773.

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Thesis (Ph. D.)--West Virginia University, 1999.<br>Title from document title page. Document formatted into pages; contains ix, 137 p. : ill. Vita. Includes abstract. Includes bibliographical references (p. 115-134).
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Pandey, Rajiv 1967. "Crystal size manipulation of acetaminophen via recrystallization." Thesis, The University of Arizona, 1993. http://hdl.handle.net/10150/278344.

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The crystal size distribution (CSD) of any material determines its end use. Consequently, comminution processes are used to transform material from one size distribution to another. Often, recrystallization from solution is one of the processes used. Recently, a novel recrystallization process named the GAS process was developed to mill compounds that were thermally labile and insoluble in supercritical fluids. CSD could be manipulated using this process. To further illustrate the applicability of this process, size manipulation studies of acetaminophen (a widely available drug) were performed
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Ito, Yoshiya, Nancy Machen, Edward Abril, and Robert McCuskey. "Effects of acetaminophen on hepatic microcirculation in mice." BioMed Central, 2004. http://hdl.handle.net/10150/610123.

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Books on the topic "Acetaminophen"

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Hankin, Lester. Analysis of products containing acetaminophen. Connecticut Agricultural Experiment Station, 1986.

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Hankin, Lester. Analysis of products containing acetaminophen. Connecticut Agricultural Experiment Station, 1986.

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Weglicki, Peter S. Free radical reactions of acetaminophen. University of Salford, 1987.

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Folkenberg, Judy. Acetaminophen-codeine: How to take your medicine. Dept. of Health and Human Services, Food and Drug Administratrion, 1991.

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Folkenberg, Judy. Acetaminophen-codeine: How to take your medicine. Dept. of Health and Human Services, Food and Drug Administratrion, 1991.

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Folkenberg, Judy. Acetaminophen-codeine: How to take your medicine. Dept. of Health and Human Services, Food and Drug Administratrion, 1991.

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Folkenberg, Judy. Acetaminophen-codeine: How to take your medicine. Dept. of Health and Human Services, Food and Drug Administratrion, 1991.

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Lin, Meng-Chih. Post-consolidation behaviour of acetaminophen crystals. National Library of Canada = Bibliothèque nationale du Canada, 1993.

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Foisy, Michelle M. An Overview of Acetaminophen overdoses at the Ottawa General Hospital. s.n., 1989.

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Parker, James N., and Philip M. Parker. Acetaminophen: A medical dictionary, bibliography, and annotated research guide to Internet references. ICON Health Publications, 2004.

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Book chapters on the topic "Acetaminophen"

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Slika, Rania. "Acetaminophen." In Textbook of Clinical Pediatrics. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-02202-9_272.

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Kerstenetzky, Luiza. "Acetaminophen." In Pain. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-99124-5_53.

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Bährle-Rapp, Marina. "Acetaminophen." In Springer Lexikon Kosmetik und Körperpflege. Springer Berlin Heidelberg, 2007. http://dx.doi.org/10.1007/978-3-540-71095-0_59.

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Kim, David J., and Srdjan S. Nedeljkovic. "Acetaminophen." In Pain Medicine. Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-43133-8_41.

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George, David J. "Acetaminophen." In Poisons. CRC Press, 2017. http://dx.doi.org/10.1201/9781315371757-17.

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Brennan, Kristin, and Henry Liu. "Acetaminophen." In First Aid Perioperative Ultrasound. Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-21291-8_7.

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Edwards, David A., and Obi Okwuchukwu. "Acetaminophen." In Hospitalized Chronic Pain Patient. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-08376-1_30.

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de Groot, Anton C. "Acetaminophen." In Monographs In Contact Allergy. CRC Press, 2022. http://dx.doi.org/10.1201/9781003158004-7.

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Champion, Howard R., Nova L. Panebianco, Jan J. De Waele, et al. "Acetaminophen Overdose." In Encyclopedia of Intensive Care Medicine. Springer Berlin Heidelberg, 2012. http://dx.doi.org/10.1007/978-3-642-00418-6_795.

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Bateman, D. Nicholas. "Acetaminophen (Paracetamol)." In Critical Care Toxicology. Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-20790-2_108-1.

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Conference papers on the topic "Acetaminophen"

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Jagadeesan, Prem, and Shweta Singh. "Model assessment for Design of Future Manufacturing systems using Digital Twins: A case study on a single-scale pharmaceutical manufacturing unit." In Foundations of Computer-Aided Process Design. PSE Press, 2024. http://dx.doi.org/10.69997/sct.110967.

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Designing a digital twin will be crucial in developing automation-based future manufacturing systems. The design of digital twins involves data-driven modelling of individual manufacturing units and interactions between the various entities. The goals of future manufacturing units such as zero waste at the plant scale can be formulated as a model-based optimal control problem by identifying the necessary state, control inputs, and manipulated variables. The fundamental assumption of any model-based control scheme is the availability of a �reasonable model�, and hence, assessing the goodness of
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Vemula, Praveen Kumar, Gregory A. Cruikshank, George John, and Jeffrey M. Karp. "Enzyme responsive acetaminophen hydrogels." In 2009 IEEE 35th Annual Northeast Bioengineering Conference. IEEE, 2009. http://dx.doi.org/10.1109/nebc.2009.4967713.

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Kordić, Nikolina Benco, Mila Lovrić, and Arnes Rešić. "194 Late-presenting acetaminophen self-poisoning." In 10th Europaediatrics Congress, Zagreb, Croatia, 7–9 October 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-europaediatrics.194.

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Munawar, I., S. Singh, and R. Dean. "Why Isn't the Acetaminophen Level Improving?" In American Thoracic Society 2023 International Conference, May 19-24, 2023 - Washington, DC. American Thoracic Society, 2023. http://dx.doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a5203.

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Kordić, Nikolina Benco, and Arnes Rešić. "195 Intravenous acetaminophen overdose – a therapeutic error." In 10th Europaediatrics Congress, Zagreb, Croatia, 7–9 October 2021. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2021. http://dx.doi.org/10.1136/archdischild-2021-europaediatrics.195.

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Patel, Swet M., James A. Espinosa, and Alan Lucerna. "Over the Counter Overdose: A Case of Tylenol Toxicity." In 28th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2024. http://dx.doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.80_2024.

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We report a case of a 51-year-old man presenting to the Emergency Department (ED) with suicidal ideations (SI) endorsing an intentional overdose of acetaminophen. Just as important is the clinical presentation; it is equally important to obtain a detailed history of patient's presentation leading to the ED visit when evaluating a suicide attempt. Tylenol (acetaminophen) is a common over the counter (OTC) medication available to the public. Management of Tylenol overdose follows a standard outline of things to observe and intervene on. In this case, we discuss how Tylenol overdose is managed in
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Elfers, C., KM Schneider, A. Ghallab, et al. "Intestinal dysbiosis amplifies acetaminophen induced acute liver injury." In 36. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0039-3402103.

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Ghallab, A., R. Hassan, M. Myllys, et al. "A so far unrecognized mechanism of acetaminophen hepatotoxicity." In 37. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0040-1721954.

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Malesker, M. A., D. E. Hilleman, and L. E. Morrow. "Systematic Review of Intravenous Acetaminophen After Cardiac Surgery." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3396.

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Fitzgerald, T., and M. A. Arroyo Morr. "Vaping-Associated Lung Injury From Oxycodone-Acetaminophen Inhalation." In American Thoracic Society 2024 International Conference, May 17-22, 2024 - San Diego, CA. American Thoracic Society, 2024. http://dx.doi.org/10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a6172.

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Reports on the topic "Acetaminophen"

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ชัยลภากุล, อรวรรณ. การวิเคราะห์ทางเคมีไฟฟ้าในระบบโฟลอินเจคชันของสารประกอบยาโดยใช้ขั้วไฟฟ้าฟิล์มบางของเพชรซึ่งโดปด้วยโบรอน : รายงานผลการวิจัย. จุฬาลงกรณ์มหาวิทยาลัย, 2002. https://doi.org/10.58837/chula.res.2002.43.

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ในงานวิจัยนี้ได้ทำการวิเคราะห์ทางเคมีไฟฟ้าของ acetaminophen และ ampicillin sodium ในสารละลาย 0.1 M ฟอสเฟตบัฟเฟอร์ด้วยขั้วไฟฟ้าฟิล์มบางของเพชรโดยใช้เทคนิคไซคลิกโวลแทมเมทรี พบว่า acetaminophen และ ampicillin sodium ให้สัญญาณที่ขั้วไฟฟ้าฟิล์มบางของเพชรที่ชัดเจนกว่าสัญญาณที่ได้จากการใช้ขั้วไฟฟ้ากลาสซี จากผลการทดลองพบว่า acetaminophen ให้ความสัมพันธ์เป็นเส้นตรงอยู่ในช่วง 0.1-8.0 mM และความเข้มข้นต่ำสุดที่สามารถตรวจวัดได้เมื่อใช้ขั้วไฟฟ้าฟิล์มบางของเพชรมีค่าเท่ากับ 10 micrometre (S/B = 3) สำหรับ ampicillin sodium ให้ความสัมพันธ์เป็นเส้นตรงอยู่ในช่วง 0.5-15 mM และความเข้มข้นต่ำสุดที่สามารถตรวจวัดได้เ
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Savarie, Peter J. Development of Non-prey Baits for Delivery of Acetaminophen to Brown Treesnakes (Boiga irregularis) on Guam. Version 3. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada581124.

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Chou, Roger, Jesse Wagner, Azrah Y. Ahmed, et al. Treatments for Acute Pain: A Systematic Review. Agency for Healthcare Research and Quality (AHRQ), 2020. http://dx.doi.org/10.23970/ahrqepccer240.

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Objectives. To evaluate the effectiveness and comparative effectiveness of opioid, nonopioid pharmacologic, and nonpharmacologic therapy in patients with specific types of acute pain, including effects on pain, function, quality of life, adverse events, and long-term use of opioids. Data sources. Electronic databases (Ovid® MEDLINE®, PsycINFO®, Embase®, the Cochrane Central Register of Controlled Trials, and the Cochrane Database of Systematic Reviews) to August 2020, reference lists, and a Federal Register notice. Review methods. Using predefined criteria and dual review, we selected randomiz
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Halker Singh, Rashmi B., Juliana H. VanderPluym, Allison S. Morrow, et al. Acute Treatments for Episodic Migraine. Agency for Healthcare Research and Quality (AHRQ), 2020. http://dx.doi.org/10.23970/ahrqepccer239.

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Abstract:
Objectives. To evaluate the effectiveness and comparative effectiveness of pharmacologic and nonpharmacologic therapies for the acute treatment of episodic migraine in adults. Data sources. MEDLINE®, Embase®, Cochrane Central Registrar of Controlled Trials, Cochrane Database of Systematic Reviews, PsycINFO®, Scopus, and various grey literature sources from database inception to July 24, 2020. Comparative effectiveness evidence about triptans and nonsteroidal anti-inflammatory drugs (NSAIDs) was extracted from existing systematic reviews. Review methods. We included randomized controlled trials
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