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Journal articles on the topic 'Acetazolamide'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 July 2024

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1

Leaf, David E., and David S. Goldfarb. "Mechanisms of action of acetazolamide in the prophylaxis and treatment of acute mountain sickness." Journal of Applied Physiology 102, no. 4 (April 2007): 1313–22. http://dx.doi.org/10.1152/japplphysiol.01572.2005.

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Acetazolamide, a potent carbonic anhydrase (CA) inhibitor, is the most commonly used and best-studied agent for the amelioration of acute mountain sickness (AMS). The actual mechanisms by which acetazolamide reduces symptoms of AMS, however, remain unclear. Traditionally, acetazolamide's efficacy has been attributed to inhibition of CA in the kidneys, resulting in bicarbonaturia and metabolic acidosis. The result is offsetting hyperventilation-induced respiratory alkalosis and allowance of chemoreceptors to respond more fully to hypoxic stimuli at altitude. Studies performed on both animals and humans, however, have shown that this explanation is unsatisfactory and that the efficacy of acetazolamide in the context of AMS is likely due to a multitude of effects. This review summarizes the known systemic effects of acetazolamide and incorporates them into a model encompassing several factors that are likely to play a key role in the drug's efficacy. Such factors include not only metabolic acidosis resulting from renal CA inhibition but also improvements in ventilation from tissue respiratory acidosis, improvements in sleep quality from carotid body CA inhibition, and effects of diuresis.

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2

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 694 (March 1998): 6. http://dx.doi.org/10.2165/00128415-199806940-00015.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 764 (August 1999): 6. http://dx.doi.org/10.2165/00128415-199907640-00015.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1167 (September 2007): 5. http://dx.doi.org/10.2165/00128415-200711670-00013.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1170 (September 2007): 7. http://dx.doi.org/10.2165/00128415-200711700-00014.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1191 (March 2008): 5. http://dx.doi.org/10.2165/00128415-200811910-00010.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1154 (June 2007): 5. http://dx.doi.org/10.2165/00128415-200711540-00015.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1369 (September 2011): 7. http://dx.doi.org/10.2165/00128415-201113690-00018.

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9

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 564 (August 1995): 4. http://dx.doi.org/10.2165/00128415-199505640-00005.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 568 (September 1995): 5. http://dx.doi.org/10.2165/00128415-199505680-00009.

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11

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 424 (October 1992): 5. http://dx.doi.org/10.2165/00128415-199204240-00017.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 450 (May 1993): 5. http://dx.doi.org/10.2165/00128415-199304500-00013.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 461 (July 1993): 5. http://dx.doi.org/10.2165/00128415-199304610-00022.

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14

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 645 (April 1997): 5. http://dx.doi.org/10.2165/00128415-199706450-00011.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 677 (November 1997): 7. http://dx.doi.org/10.2165/00128415-199706770-00019.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 781 (December 1999): 6. http://dx.doi.org/10.2165/00128415-199907810-00018.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 838 (February 2001): 7. http://dx.doi.org/10.2165/00128415-200108380-00014.

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18

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1411 (July 2012): 5. http://dx.doi.org/10.2165/00128415-201214110-00013.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 907 (June 2002): 6. http://dx.doi.org/10.2165/00128415-200209070-00010.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 918 (September 2002): 6. http://dx.doi.org/10.2165/00128415-200209180-00011.

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21

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 933 (January 2003): 9. http://dx.doi.org/10.2165/00128415-200309330-00011.

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22

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1269 (September 2009): 5. http://dx.doi.org/10.2165/00128415-200912690-00014.

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23

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1272 (October 2009): 5. http://dx.doi.org/10.2165/00128415-200912720-00012.

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24

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1280 (November 2009): 8. http://dx.doi.org/10.2165/00128415-200912800-00024.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1247-1248 (April 2009): 4. http://dx.doi.org/10.2165/00128415-200912470-00013.

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26

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 317 (September 1990): 3. http://dx.doi.org/10.2165/00128415-199003170-00004.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 320 (September 1990): 4. http://dx.doi.org/10.2165/00128415-199003200-00004.

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28

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 321 (October 1990): 4. http://dx.doi.org/10.2165/00128415-199003210-00007.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 329 (December 1990): 3. http://dx.doi.org/10.2165/00128415-199003290-00004.

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30

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 332 (December 1990): 3. http://dx.doi.org/10.2165/00128415-199003320-00005.

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31

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 335 (January 1991): 3. http://dx.doi.org/10.2165/00128415-199103350-00006.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 347 (April 1991): 3. http://dx.doi.org/10.2165/00128415-199103470-00004.

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33

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1310 (July 2010): 8. http://dx.doi.org/10.2165/00128415-201013100-00018.

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34

&NA;. "Acetazolamide." Drugs & Therapy Perspectives 7, no. 6 (April 1996): 11–13. http://dx.doi.org/10.2165/00042310-199607060-00006.

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35

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 964 (August 2003): 6. http://dx.doi.org/10.2165/00128415-200309640-00012.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1300 (May 2010): 5. http://dx.doi.org/10.2165/00128415-201013000-00011.

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37

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1301 (May 2010): 6. http://dx.doi.org/10.2165/00128415-201013010-00019.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1304 (June 2010): 6. http://dx.doi.org/10.2165/00128415-201013040-00018.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1036 (January 2005): 6. http://dx.doi.org/10.2165/00128415-200510360-00015.

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40

Richalet, Jean-Paul, Maria Rivera, Patrick Bouchet, Eduardo Chirinos, Igor Onnen, Olivier Petitjean, Annick Bienvenu, Francçoise Lasne, Stéphane Moutereau, and Fabiola León-Velarde. "Acetazolamide." American Journal of Respiratory and Critical Care Medicine 172, no. 11 (December 2005): 1427–33. http://dx.doi.org/10.1164/rccm.200505-807oc.

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41

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 485 (January 1994): 6. http://dx.doi.org/10.2165/00128415-199404850-00021.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1341 (March 2011): 5. http://dx.doi.org/10.2165/00128415-201113410-00011.

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&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1342 (March 2011): 5. http://dx.doi.org/10.2165/00128415-201113420-00014.

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44

&NA;. "Acetazolamide." Reactions Weekly &NA;, no. 1346 (April 2011): 5. http://dx.doi.org/10.2165/00128415-201113460-00012.

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45

Kassamali, Rahim, and Domenic A. Sica. "Acetazolamide." Cardiology in Review 19, no. 6 (November 2011): 276–78. http://dx.doi.org/10.1097/crd.0b013e31822b4939.

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46

"Acetazolamide." Reactions Weekly 1856, no. 1 (May 2021): 13. http://dx.doi.org/10.1007/s40278-021-96006-7.

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47

"Acetazolamide." Reactions Weekly 1847, no. 1 (March 2021): 18. http://dx.doi.org/10.1007/s40278-021-92575-2.

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48

"Acetazolamide." Reactions Weekly 1848, no. 1 (March 2021): 14. http://dx.doi.org/10.1007/s40278-021-93016-2.

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49

"Acetazolamide." Reactions Weekly 1852, no. 1 (April 2021): 18. http://dx.doi.org/10.1007/s40278-021-94471-y.

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"Acetazolamide." Reactions Weekly 1852, no. 1 (April 2021): 17. http://dx.doi.org/10.1007/s40278-021-94470-y.

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