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Journal articles on the topic 'Acetonitrile-water binary system'

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Published: 3 June 2025

Last updated: 31 July 2025

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1

Nowakowska, Joanna, Piotr Pikul, Krzesimir Ciura, and Jakub Piotrowicz. "A simple TLC and HPTLC method for separation of selected steroid drugs." Open Chemistry 11, no. 8 (2013): 1297–308. http://dx.doi.org/10.2478/s11532-013-0258-8.

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AbstractChromatographic properties of five steroid drugs: cortisone, hydrocortisone, methylprednisolone, prednisolone and norgestrel have been studied by normal-, reversed-phase and hydrophilic neutral cyano-bonded silica stationary phase with five binary mobile phases (acetonitrile-water, acetonitrile-DMSO, acetonitrile-methanol, acetone-petroleum ether, acetone-water) in which the concentration of organic modifier was varied from 0 to 100% (v/v). This study reports the optimization of steroid hormones separation. Chromatographic retention data and possible retention mechanisms are discussed.

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Baranović, Goran. "Refractive Index Mixing Rules and Excess Infrared Spectra of Binary Mixtures." Applied Spectroscopy 71, no. 5 (2016): 1039–49. http://dx.doi.org/10.1177/0003702816668532.

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Three refractive index mixing rules, Arago–Biot, Lorentz–Lorenz, and Newton, are generalized to complex refractive index and used to define infrared (IR) spectra of the corresponding ideal liquid mixtures. Using the measured optical constants n and k for acetonitrile-water mixtures (Bertie and Lan, 1997) the excess absorbances, AE = Aobs − Aideal, are calculated. Relying upon the well-established properties of the acetonitrile–water mixtures, the interpretation of the excess absorbances is established that is essentially based on the understanding of a liquid as a set of oscillators. The set d

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3

Goronja, Jelena, Aleksandra Janosevic-Lezaic, Biljana Dimitrijevic, Andjelija Malenovic, Dragomir Stanisavljev, and Natasa Pejic. "Determination of critical micelle concentration of cetyltrimethylammonium bromide: Different procedures for analysis of experimental data." Chemical Industry 70, no. 4 (2016): 485–92. http://dx.doi.org/10.2298/hemind150622055g.

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Conductivity of two micellar systems was measured in order to determine critical micelle concentration (CMC) of cetyltrimethylammonium bromide (CTAB). Those systems were: CTin water and CTin binary mixture acetonitrile (ACN)-water. Conductivity (?)-concentration (c) data were treated by four different methods: conventional method, differential methods (first and second derivative) and method of integration (methods A-D, respectively). As CTin water micellar system shows a sharp transition between premicellar and postmicellar part of the ?/c curve, any of the applied methods gives reliable CMC

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Pauletti, Michela, Vladimir V. Rybkin, and Marcella Iannuzzi. "Surface tension of liquids and binary mixtures from molecular dynamics simulations." Journal of Physics: Condensed Matter 34, no. 4 (2021): 044003. http://dx.doi.org/10.1088/1361-648x/ac2e8f.

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Abstract In this work we assess and extend strategies for calculating surface tension of complex liquids from molecular dynamics simulations: the mechanical route and the instantaneous liquid interface (ILI) approach. The former employs the connection between stress tensor and surface tension, whereas the latter involves computation of instantaneous density field. Whereas the mechanical route is general, the ILI method involves system-dependent parameters restricting its original application to liquid water only. Here we generalize the approach to complex molecular liquids using atomic van der

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Kovačević, Strahinja, Milica Karadžić Banjac, Jasmina Anojčić, et al. "Comparative Analysis of Anisotropic Lipophilicity of a Series of 6-Chloro-1,3,5-Triazines Determined in Reversed Phase Ultra High Performance Liquid Chromatography System." Agriculture 13, no. 12 (2023): 2212. http://dx.doi.org/10.3390/agriculture13122212.

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Triazine derivatives are well-known commercially available compounds used for selective weed control in different crops, such as corn and sugarcane. Some of them are considered persistent organic compounds in the environment and it is important to improve the features of herbicide formulae, to estimate their physicochemical properties and to determine their retention behavior in modern analytical techniques that can be used in the determination of pesticides in environmental samples. The present study deals with a comprehensive analysis of the chromatographic behavior of a series of 6-chloro-1

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Vláčil, František, and Věra Hamplová. "A contribution to the description of the retention mechanism of metal chelates during their reversed-phase chromatography." Collection of Czechoslovak Chemical Communications 50, no. 10 (1985): 2221–27. http://dx.doi.org/10.1135/cccc19852221.

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Mercury(II) diethyldithiocarbamate was chromatographed on silica gel with chemically bonded octadecyl groups using aqueous mixtures with methanol, acetonitrile, dioxane, and tetrahydrofuran, respectively, as the mobile phase, and the dependence of logarithm of the capacity ratio (k) on the volume fraction of water in the binary mobile phase was examined. Also, the dependence of k on the liquid-liquid extraction distribution ratio in an aqueous methanol-n-alkane extraction system was investigated for Cu, Co, Ni, Pb, and Hg diethyldithiocarbamates. Both kinds of dependence are linear, which sugg

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Ryzhkin, Dmitry A., and Valentina M. Raeva. "ANALYSIS OF ENERGY CONSUMPTION OF EXTRACTIVE DISTILLATION FLOWSHEETS OF FOUR-COMPONENT SOLVENT MIXTURE." IZVESTIYA VYSSHIKH UCHEBNYKH ZAVEDENII KHIMIYA KHIMICHESKAYA TEKHNOLOGIYA 64, no. 6 (2021): 47–55. http://dx.doi.org/10.6060/ivkkt.20216406.6326.

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A comparative analysis of energy consumption for extractive distillation flowsheets was carried out. This was done by the example of methanol - ethanol - acetonitrile - mixture. These solvents are used in pharmaceutical industries. The basic system methanol - ethanol - acetonitrile - water contains four binary and one ternary minimum-boiling azeotropes. Pressure change has almost no effect on the location of separatric surfaces. Therefore, extractive distillation should be used to separate solvents mixtures of any composition. Industrial entrainers dimethyl sulfoxide and glycerol are considere

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Ciura, Krzesimir, Joanna Nowakowska, Piotr Pikul, Wiktoria Struck-Lewicka, and Michał J. Markuszewski. "A Comparative Quantitative Structure-Retention Relationships Study for Lipophilicity Determination of Compounds with a Phenanthrene Skeleton on Cyano-, Reversed Phase-, and Normal Phase-Thin Layer Chromatography Stationary Phases." Journal of AOAC INTERNATIONAL 98, no. 2 (2015): 345–53. http://dx.doi.org/10.5740/jaoacint.14-187.

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Abstract The phenanthrene skeleton is an important moiety in medical chemistry as it is present in steroidal drugs used as anti-inflammatory and anti-asthmatic agents as well as synthetic hormones or potassium sparing diuretics. Chromatographic properties of 14 derivatives containing the phenanthrene skeleton in their structure with known lipophilicityhave been studied. NP, RP, and cyano-bonded silica stationary phaseswith three binary mobile phases (acetonitrile–water, acetone–water, and acetone–petroleum ether) were tested. Obtained chromatographic data were correlated with the lipophilicity

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Szabó, Zoltán-István, Ágnes Bartalis-Fábián, and Gergő Tóth. "Simultaneous Determination of Escitalopram Impurities including the R-enantiomer on a Cellulose tris(3,5-Dimethylphenylcarbamate)-Based Chiral Column in Reversed-Phase Mode." Molecules 27, no. 24 (2022): 9022. http://dx.doi.org/10.3390/molecules27249022.

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A high-performance liquid chromatographic method was developed for the simultaneous determination of the related substances—three potential synthesis-related chemical impurities and the distomer—of escitalopram. The separation capacity of seven different polysaccharide-type chiral columns, including three amylose-based (Lux Amylose-1, Lux i-Amylose-1, Lux Amylose-2) and four cellulose-based columns (Lux Cellulose-1, Lux Cellulose-2, Lux Cellulose-3, and Lux Cellulose-4) were screened in the polar organic and reversed-phase modes. Lux Cellulose-1, based on cellulose tris(3,5-dimethylphenylcarba

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Wu, Nannan, Shunli Ouyang, Junjie Cui, et al. "Investigation on the Influence of Microstructure Based on Hydrogen Bonding on Surface Tension by Raman Spectroscopy." International Journal of Analytical Chemistry 2019 (December 29, 2019): 1–7. http://dx.doi.org/10.1155/2019/7975237.

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Surface tension (http://mts.hindawi.com/update/) in our Manuscript Tracking System and after you have logged in click on the ORCID link at the top of the page. This link will take you to the ORCID website where you will be able to create an account for yourself. Once you have done so, your new ORCID will be saved in our Manuscript Tracking System automatically."?>and Raman spectra containing hydrogen bonding in acetonitrile aqueous solutions with different mole ratios were obtained. Varied surface tension and hydrogen bonding in the mixed solution were discussed. For this purpose, the OH st

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Ajay, S. Rana, K. Upadhyay Navneet, Sapra Sameer, and Sharma Megha. "VALIDATION AND DEVELOPMENT OF A RP-HPLC METHOD FOR DETERMINATION OF GLYCOSIDE (SALICIN) IN AN AYURVEDIC PREPARATION." Pharmaceutical and Chemical Journal 1, no. 1 (2014): 1–5. https://doi.org/10.5281/zenodo.13690822.

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Salicin, a glycoside isolated from <em>Salix Alba</em>, has provided us with most potent weapon, Acetyl-salicylic acid for killing pain. Separation of salicin was achieved on Agilent HPLC with Aclipse XDB-C18, 5 μm and 150mm X 4.6mm, injection volume 5 μl at flow rate of 1ml/min by using a binary pump system. The ratio of mobile phase was 80 ml: 20ml (Acetonitrile: Water). The linearity was determined by six different concentrations of Salicin in triplicate and calibration curve was plotted in range of 5-30 μg/ml. The Coefficient of determination (r<sup>2</sup>) of salicin was 0.998 f

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Gusev, K. A., D. N. Maimistov, V. I. Pavlovsky, et al. "Development of the Composition and Technology for Production a Solid Dispersion System by Hot Melt Extrusion to Increase the Bioavailability of the Active Substance." Drug development & registration 11, no. 4 (2022): 108–15. http://dx.doi.org/10.33380/2305-2066-2022-11-4-108-115.

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Introduction. The solubility of an active pharmaceutical ingredient plays a major role in drug absorption. Hot melt extrusion is a batch or continuous process that allows creating solid dispersion systems based on various carriers in order to increase solubility and bioavailability of active substances. Development of effective and safe analgesics is one of the most vital tasks of organic and medicinal chemistry. An innovative non-opioid analgesic with very low toxicity and low dosage, but practically insoluble in water, was used in this work. It was suggested to obtain a solid dispersion by h

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Hegazy, Maha A., May H. Abdelwahab, Hassan A. M. Hendawy, Soheir A. Weshahy, and Samah S. Abbas. "Selective and Sensitive Chromatographic Methods for Determination of a Co-Formulated Binary Mixture in Antibacterial Eye Drops and Aqueous Humor in the Presence of Their Degradation Products and Potential Impurities." Journal of Chromatographic Science 58, no. 1 (2020): 37–52. http://dx.doi.org/10.1093/chromsci/bmz107.

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Abstract Prednisolone acetate (PDN) is a corticosteroid anti-inflammatory liable to degradation under different conditions and used with antibiotics in eye drops. Two selective stability-indicating separation techniques were developed for simultaneous determination of PDN and moxifloxacin HCl (MXF) binary mixture in pure forms, ophthalmic formulation, in the presence of PDN impurities and in the presence of their degradation products. The first method was based on HPTLC separation using silica gel 60 F254 HPTLC plates, and a developing system of toluene: ethyl acetate: methanol: ammonia (5.0:

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Qiu, Jingxuan, Peng Wang, Shen Hu, et al. "Solid–Liquid Equilibrium of l-Thioproline in Nine Neat Solvents and Water + Acetonitrile Binary Solvent System from 283.15 to 323.15 K: Solubility Determination and Data Modeling." Journal of Chemical & Engineering Data 66, no. 2 (2021): 1201–9. http://dx.doi.org/10.1021/acs.jced.0c00996.

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15

Abdelwahab, Nada S., Nehal F. Fared, Mohamed Elagawany, and Esraa H. Abdelmomen. "Different Spectrophotometric and Chromatographic Methods for Determination of Mepivacaine and Its Toxic Impurity." Journal of AOAC INTERNATIONAL 100, no. 5 (2017): 1392–99. http://dx.doi.org/10.5740/jaoacint.16-0322.

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Abstract Stability-indicating spectrophotometric, TLC-densitometric, and ultra-performance LC (UPLC) methods were developed for the determination of mepivacaine HCl (MEP) in the presence of its toxic impurity, 2,6-dimethylanaline (DMA). Different spectrophotometric methods were developed for the determination of MEP and DMA. In a dual-wavelength method combined with direct spectrophotometric measurement, the absorbancedifference between 221.4 and 240 nm was used for MEPmeasurements, whereas the absorbance at 283 nm was used for measuring DMA in the binary mixture. In the second-derivative meth

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Tang, Linjun, Shubham Sharma, and Shyam S. Pandey. "Synthesis and Characterization of Newly Designed and Highly Solvatochromic Double Squaraine Dye for Sensitive and Selective Recognition towards Cu2+." Molecules 27, no. 19 (2022): 6578. http://dx.doi.org/10.3390/molecules27196578.

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Synthesis and characterization of a novel and zwitterionic double squaraine dye (DSQ) with a unique D-A-A-D structure is being reported. Contrary to the conventional mono and bis-squaraine dyes with D-A-D and D-A-D-A molecular frameworks reported so far, DSQ dye demonstrated strong solvatochromism allowing for the multiple ion sensing using a single probe by judicious selection of the suitable solvent system. The DSQ dye exhibited a large solvatochromic shift of about 200 nm with color changes from the visible to NIR region with metal ion sensitivity. Utilization of a binary solvent consisted

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17

Nguyen, Dung Tien, Le Canh Trung, Nguyen Duy Cuong, et al. "Measuring the refractive index of a methanol - water mixture according to the wavelength." Photonics Letters of Poland 13, no. 1 (2021): 10. http://dx.doi.org/10.4302/plp.v13i1.1058.

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The refractive index of the methanol-water mixture depending on the wavelength at different concentrations was determined by our experimental method using a Michelson interferometer system. A comparative study of Gladstone-Dale, Arago–Biot and Newton relations for predicting the refractive index of a liquid has been carried out to test their validity for the methanol-water mixture with the different concentrations 30%, 40%, 50%, 60%, 80%, and 100%. The comparison shows the good agreement between our experimental results and the results in the expressions studied over the wavelength range appro

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Al-Tannak, Naser F., Nada A. Al-Hasawi, and Ladislav Novotny. "UHPLC-UV Analysis of Morin and Structurally Related Flavonoids with Potential Anticancer Activity." Current Pharmaceutical Analysis 15, no. 4 (2019): 295–304. http://dx.doi.org/10.2174/1573412914666171220154224.

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Background: Flavonoids as secondary metabolites of plants fulfill various functions in cell protection. They are of a considerable scientific interest because of their potentially medical use due to their anticancer, chemoprotective, antimicrobial, antiallergic, anti-inflammatory and antiviral activities. </P><P> Objective: The study aimed to develop a new UHPLC-UV method for morin and 2 other structurally related flavonoids - naringenin and kaempferol as the structural similarity of huge numbers of flavonoids does not limit their various biological functions and activities. Method

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Czauderna, Marian, Małgorzata Białek, Edyta Molik, and Kamil Zaworski. "The Improved Method for Determination of Orotic Acid in Milk by Ultra-Fast Liquid Chromatography with Optimized Photodiode Array Detection." Animals 11, no. 11 (2021): 3196. http://dx.doi.org/10.3390/ani11113196.

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Ultra-fast liquid chromatography (UFLC) with a photodiode array detector (DAD) for simple and rapid determination of orotic acid (OAc) in milk of sheep and cows is described. Milk samples are treated with acetonitrile (1:1, v/v) and then centrifuged at 4 °C. To 1 mL of the obtained supernatant 9 mL of ultrapure water was added. Subsequently, 0.5–6 µL of the resulting solution was injected into the UFLC-DAD system. Separation and quantification of OAc in milk samples was achieved using two Kinetex C18 columns (1.7 µm, 150 mm × 2.1 mm, i.d., 100 Å; Phenomenex) fitted with a pre-column of 4 mm ×

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Douhéret, Gérard, Collette Moreau, and André Viallard. "Excess thermodynamic quantitites in binary systems of non-electrolytes 3. Graphical representation—application to water-acetonitrile systems." Fluid Phase Equilibria 26, no. 3 (1986): 221–49. http://dx.doi.org/10.1016/0378-3812(86)80021-8.

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Douhéret, Gérard, Colette Moreau, and André Viallard. "Excess thermodynamic quantities in binary systems of non electrolytes. II. calculation-application to water-acetonitrile mixtures." Fluid Phase Equilibria 22, no. 3 (1985): 289–319. http://dx.doi.org/10.1016/0378-3812(85)87028-x.

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Rafati, Amir Abbas, Ahmad Bagheri, and Mojgan Najafi. "Experimental Data and Correlation of Surface Tensions of the Binary and Ternary Systems of Water + Acetonitrile + 2-Propanol at 298.15 K and Atmospheric Pressure." Journal of Chemical & Engineering Data 55, no. 9 (2010): 4039–43. http://dx.doi.org/10.1021/je1001329.

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Mallika, Sanyal. "Study on complex formation of dicyclohexyl-18-crown-6 with Mg2+, Ca2+ and Sr2+ in acetonitrile-water binary mixtures by conductometry." J. of Physical and Chemical Sciences Volume 1, Issue 2 (2014). https://doi.org/10.5281/zenodo.898813.

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The complexation reactions between Mg2+, Ca2+ and Sr2+ cations and dicyclohexyl-18-crown-6 (DCH 18C6) have been studied in acetonitrile–water binary mixtures at different temperatures by conductometry. The formation constants of the resulting 1:1 (M:L) complexes for all the three cations were determined from computer fitting of the molar conductance versus mole ratio data. The results show that the selectivity order of DCH 18C6 for the metal cations in the acetonitrile-water binary solvent at different temperatures (25, 35 and 45 ºC) was Sr2+ > Ca2+ > Mg2+ based on size fit concept. A li

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Mallika, Sanyal. "Study on complex formation of dicyclohexyl-18-crown-6 with Mg2+, Ca2+ and Sr2+ in acetonitrile-water binary mixtures by conductometry." J. of Physical and Chemical Sciences Volume 1, Issue 2 (2017). https://doi.org/10.5281/zenodo.999436.

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The complexation reactions between Mg2+, Ca2+ and Sr2+ cations and dicyclohexyl-18-crown-6 (DCH 18C6) have been studied in acetonitrile–water binary mixtures at different temperatures by conductometry. The formation constants of the resulting 1:1 (M:L) complexes for all the three cations were determined from computer fitting of the molar conductance versus mole ratio data. The results show that the selectivity order of DCH 18C6 for the metal cations in the acetonitrile-water binary solvent at different temperatures (25, 35 and 45 ºC) was Sr2+ > Ca2+ > Mg2+ based on size fit concept. A li

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Rudakov, Oleg Borisovich, Liudmila V. Rudakova, and Vladimir F. Selemenev. "Acetonitrile as tops solvent for liquid chromatography and extraction." Journal of Analytical Chromatography and Spectroscopy 1, no. 2 (2018). http://dx.doi.org/10.24294/jacs.v1i2.883.

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This article deals with acetonitrile physico-chemical properties and its mixtures with water. It covers the information about isotherms of such parameters of the acetonitrile-water binary system as density, viscosity, permeation coefficient, refraction index, optic density, a boiling point isobar. Authors suggest a generalized criterion of acetonitrile polarity. The article also discusses means of polarity assessment and eluotropic strength of mobile phases on the basis of acetonitrile mixtures with water with application of generalized criteria. Special attention is paid to the options of ace

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Hu, Tien-Yu, and Cheng-Hsiu Yu. "Solubility of Sodium Acetate in a Water + Acetonitrile Binary Solvent System and the Mixture Density." Journal of Chemical & Engineering Data, February 25, 2025. https://doi.org/10.1021/acs.jced.4c00563.

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Nagulancha, Bhujanga Rao, and Koteswara Rao Vandavasi. "Stability‐indicating method development and validation for quantitative estimation of organic impurities of the antidiabetic drug glipizide in drug substance and pharmaceutical dosage form using HPLC." Biomedical Chromatography, August 27, 2023. http://dx.doi.org/10.1002/bmc.5727.

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AbstractGlipizide is an antidiabetic drug used for the treatment of type 2 diabetes. A simple, reliable and robust reverse‐phase liquid chromatographic method (RP‐HPLC) was developed and validated as per International Conference on Harmonization Q2(R1) for estimating the impurities of glipizide in pharmaceutical formulations. The chromatographic separation was carried out on a Phenomenex Luna C18 (2), 250 × 4.6 mm, 5 μm with a binary solvent delivery system [MP‐A, a homogenous mixture of water and acetonitrile in a ratio of 90:10 (v/v) and 1 ml of orthophosphoric acid; and MP‐B, a homogenous m

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Qiu, Jingxuan, Haishuang Huang, Hui He, et al. "Measurement and Correlation of trans-4-Hydroxy-l-proline Solubility in Sixteen Individual Solvents and a Water + Acetonitrile Binary Solvent System." Journal of Chemical & Engineering Data, December 16, 2020. http://dx.doi.org/10.1021/acs.jced.0c00794.

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Obradović, Darija, Teresa Kowalska, and Danica Agbaba. "Mixed-Mode Hydrophilic Interactions/Reversed-Phase Retention Mechanism in Thin-Layer Chromatography." Journal of Chromatographic Science, June 4, 2021. http://dx.doi.org/10.1093/chromsci/bmab068.

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Abstract We investigated the dual retention mechanism in thin-layer chromatography taking place on three stationary phases of different polarity (C-18, plain silica gel and DIOL) and using binary mobile phases composed of acetonitrile as the main component and water, or methanol as a modifier. As the test analytes, we selected a set of 12 compounds of pharmaceutical importance and considerably different chemical structure, i.e. the imidazoline and serotonin receptor ligands, and their related compounds. Retention of each analyte in each investigated chromatographic system was determined in a w

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Nazlawy, Hagar N., Hala E. Zaazaa, Hanan A. Merey, and Shimaa A. Atty. "Green validated chromatographic methods for simultaneous determination of co-formulated oxytetracycline HCl and flunixin meglumine in the presence of their impurities in different matrices." Journal of the Iranian Chemical Society, December 21, 2022. http://dx.doi.org/10.1007/s13738-022-02699-1.

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AbstractGreen analytical chemistry is an important area of chemical sciences. So, developing competent eco-friendly analytical tools is a big challenge. This study devotes two chromatographic techniques for the simultaneous determination of a binary formulated mixture of oxytetracycline HCl (OXY) and flunixin meglumine (FLU), and their impurities tetracycline (TRC) and 2-chloronicotinic acid (CNA), respectively. Primarily, a TLC densitometric method is proposed and validated using TLC plates sprayed with 5% EDTA of pH 9 as a stationary phase and (acetonitrile/ distilled water/ ethanol 7:2:1, b

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Wei, Jie, Ximan Sun, Yuxin Zhang, et al. "The interaction of pseudo-binary system of DES (1TEAB: 3EG) with acetonitrile, ethanol and water by volumetric properties, surface properties and refractive properties." Journal of Thermal Analysis and Calorimetry, May 16, 2023. http://dx.doi.org/10.1007/s10973-023-12221-1.

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Adireddy, Krishna Kishore, Srinivasa Rao Baratam, and Nagarjuna Hari Pratap S. "RP-HPLC Method for Quantification of Etelcalcetide in Bulk and Parentral Dosage Form." Research Journal of Pharmacy and Technology, October 31, 2021, 5521–26. http://dx.doi.org/10.52711/0974-360x.2021.00963.

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A simple, rapid, accurate and precise RP-HPLC method was developed and validated for the determination of Etelcalcetide in bulk and parentral dosage form. Quantification of the drug was achieved on Shimadzu HPLC comprising of LC- 20 AD binary gradient pump, a variable wavelength programmable SPD-20A detector and SCL system controller. C18G column (250 mm x 4.6 mm, 5 μ) as stationary phase with mobile phase consisting of acetonitrile: methanol :water in the ratio of 25: 45 :30 v/v. The method showed a good linear response in the concentration range of 3.75-22.5 μg/ml with correlation coefficien

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Al-Tannak, Naser F., Fawaz Alzoubi, Fatma M. Kareem, and Ladislav Novotny. "Determination of Endocrine Disruptor Bisphenol-A leakage from Different Matrices of Dental Resin-Based Composite Materials." Current Pharmaceutical Analysis 17 (May 25, 2021). http://dx.doi.org/10.2174/1573412917666210525114226.

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Background: Bisphenol A (BPA) derivatives monomers as resins are common components in dental restorative materials and materials used for orthodontic treatment. However, they are a source for BP-A leakage, which can affect adult and child health as an endocrine disruptor. Objective: This study aimed to investigate the level of BPA leakage from four selected weights (0.1, 0.2, 0.3, 0.4 mg) of five different resin combinations used in dental restorative materials. Method: The resin combinations were cured with light for 20 seconds, kept in 1 mL of acetonitrile, and sonicated for 30 minutes. Sepa

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Brooks, Blondie O., Giacomo Maria Paganotti, Amos Massele, Enoch Sepako, Paul Adiukwu, and Kwenga Festus Sichilongo. "A simple and rapid external standard calibration HPLC method for determination of lumefantrine in dried blood spot samples from malaria patients in Botswana." Biomedical Chromatography, October 16, 2023. http://dx.doi.org/10.1002/bmc.5762.

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AbstractA simple external calibration liquid chromatography‐diode array detector method was developed, validated, and applied for the determination of lumefantrine (Lum) in dried blood spot (DBS) samples collected from malaria patients in Botswana. The samples were validated in accordance with the United States Food and Drug Administration guidelines for bioanalytical methods after sample preparation using solid–liquid extraction. Separation was achieved using an XTerra C18 column (50 × 4.6 mm, 5 μm), and a binary solvent system of acetonitrile and water adjusted to pH 2.3 was used as the mobi

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Yang, Jinchuan, Ben Pointer, and Paul Rainville. "Separation of Nonivamide and Capsaicin by Ultrahigh-Performance Liquid Chromatography for Routine Analysis of Capsaicinoids in Capsicum Products." Journal of AOAC INTERNATIONAL, September 29, 2022. http://dx.doi.org/10.1093/jaoacint/qsac115.

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Abstract Background Baseline separation of nonivamide (NON) and capsaicin (CAP) has not been achieved by using the existing liquid chromatography (LC) methods for the capsaicinoid analysis. This could lead to large errors in the determination of capsaicinoids for capsicum products. Objective The development of an ultrahigh-performance liquid chromatography (UHPLC) method that simultaneously separates NON and CAP as well as other capsaicinoids for the routine analysis of capsaicinoids in capsicum products. Method Capsaicinoids were separated on a Waters CORTECSTM T3 Column (2.1 mm i.d. x 150 mm

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El-Kafrawy, Dina S., Ahmed G. Abdelhamid, Magdi M. Abdel-Khalek, and Tarek S. Belal. "Forced Degradation and Stability-Indicating Study for the Binary Mixture of Allopurinol and Thioctic Acid Using Validated HPLC-DAD Method." Journal of AOAC INTERNATIONAL, February 27, 2023. http://dx.doi.org/10.1093/jaoacint/qsad028.

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Abstract Background Careful review of the scientific databases revealed that no stability-indicating analytical method is available for the binary mixture of Allopurinol (ALO) and Thioctic Acid (THA). Objective A comprehensive stability-indicating HPLC-DAD procedure has been executed for concurrent analysis of ALO and THA. Methods Successful chromatographic separation of the cited drugs was reached using Durashell C18 column (4.6 × 250 mm, 5 µm particle size). The mobile phase was comprised of a mixture of acidified water (pH 4.0) using phosphoric acid and acetonitrile pumped in gradient eluti

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Karabulut, Hatice, Semra Unal, Songul Ulag, Anton Ficai, Denisa Ficai, and Oguzhan Gunduz. "Mapping the Influence of Solvent Composition over the Characteristics of Polylactic Acid Nanofibers Fabricated by Electrospinning." ChemistrySelect 9, no. 17 (2024). http://dx.doi.org/10.1002/slct.202301142.

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AbstractThis study investigated the solubility of poly(lactic acid) (PLA) in various solvents (to achieve an 8 % (w/v) polymer solution) and its impact on the morphology of electrospun PLA nanofibers. Several solvents, such as dichloromethane (DCM), chloroform (CHL), tetrahydrofuran (THF), acetone (AC), acetonitrile (ACTNR), dimethylformamide (DMF), dimethylacetamide (DMAc), ethylene glycol (ETGLY), distilled water (WATER), methanol (MEOH), formic acid (FA), and n‐hexane (NHX) were used in their pure and binary forms at several ratios (4 : 1, 2 : 1, 1 : 1, 1 : 2, 1 : 3, and 1 : 4). The study a

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Mukesh, M. Maisuria. "Thermodynamic studies on metal complexes of Pb2+, Zn2+, Sr2+ and Mg2+ with 2-amino pyrimidine in water and water-acetonitrile binary solvent systems at 298.15 K, 308.15 K and 318.15 K by conductometric method." J. of Physical and Chemical Sciences Volume 4, Issue 1 (2016). https://doi.org/10.5281/zenodo.999153.

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Stability constants are measured for complexes of Pb2+, Zn2+, Sr2+ and Mg2+ with 2-amino pyrimidine (AMPYM) in pure water and water-acetonitrile binary solvent systems at 298.15, 308.15 and 318.15 K by conductometric method. The results shows that the stoichiometry of the complexes of AMPYM with all investigated metal ions in all binary solvent systems is 1:2 [ML2]. The log Kf values of M2+-AMPYM complexes in H2O-ACN binary solvent systems decreases with increasing % of ACN and increased with the increase in percentage of water and also with increase in temperature. The value of formation cons

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Islam, Md Ariful, M. Mehedi Hasan Rocky, M. Shazzadul Islam, et al. "Viscometric Properties of Binary Liquid Systems: Acetonitrile + Ethanolamine, Acetonitrile + 3-Amino-1-Propanol, and Water + 3-Amino-1-Propanol from 303.15 to 323.15 K." Journal of Chemical & Engineering Data, January 7, 2025. https://doi.org/10.1021/acs.jced.4c00421.

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