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Dissertations / Theses on the topic 'Acid Derivatives'

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1

Peters, Steven Carlton. "Crosslinked amino acid derivatives." Title page, table of contents and abstract only, 1991. http://web4.library.adelaide.edu.au/theses/09PH/09php4831.pdf.

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2

Van, Kralingen Leon. "Controlled polymerization of amino acid derivatives." Thesis, Link to the Internet, 2008. https://etd.sun.ac.za/jspui/handle/10019/919.

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3

Das(, dutta) Sima. "Organotin derivatives of hydroxamic acids derived from dibasic carboxylic acid." Thesis, University of North Bengal, 1989. http://hdl.handle.net/123456789/755.

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4

Spray, Caroline Ann. "4-ketoproline derivatives as chiral templates in synthesis." Thesis, University of Sussex, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.239542.

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(2S)-trans-4-Hydroxyproline has been studied as a chiral template for the preparation of kainoids. Conversion to protected 4-ketoproline derivatives has allowed functionalisation at C-3 to be investigated. Although the tendency to epimerisation has caused problems, we have successfully introduced a variety of alkyl side chains with cis stereochemistry at this position. Functionalisation of the 3-alkyl-4-ketoprolines at C-4 has been investigated and a method has been found to prepare compounds which are functionalised stereospecifically at both C-3 and C-4. These have potential for study as kai
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5

Box, Julian M. "Towards fluorinated derivatives of shikimic acid." Thesis, University of Reading, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286003.

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6

Kociuba, Katherine. "Radical functionalisation of amino acid derivatives /." Title page, table of contents and abstract only, 1996. http://web4.library.adelaide.edu.au/theses/09PH/09phk76.pdf.

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7

Tan, Eng Wui. "Regioselective modification of amino acid derivatives /." Title page, contents and abstract only, 1990. http://web4.library.adelaide.edu.au/theses/09PH/09pht1612.pdf.

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8

Portell, Bueso Anna. "Crystal Engineering Studies of Squaric Acid Derivatives." Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/285325.

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This thesis is a multidisciplinary study of the solid state of squaric acid derivatives which combines approaches from areas such as crystal engineering, supramolecular chemistry and crystallography. The structural preferences in the solid state of this family of compounds has been analyzed, new crystalline materials derived from squaric acid have been designed in order to study new supramolecular synthons and relevant chemical phenomena such as template effect, preorganization, cooperativity and electrostatic compression have been explored. In summary, 47 polymorphs, solvates, cocrystals
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9

Goubet, D. C. M. "Asymmetric synthesis of α-amino acid derivatives". Thesis, Swansea University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637081.

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A general background to α-amino acids is discussed in the first chapter. After a brief account on classification, properties and applications of these compounds, asymmetric processes leading to optically enriched residues are reviewed in detail. The second chapter describes the envisaged stereoselective approach towards these substrates involving Michael-type addition onto a chiral didehydroalanine derivative. Syntheses of α,β-unsaturated amino acids are reviewed after a brief section on Michael-type reactions. The preparation of a chiral didehydroamino acid residue has been investigated using
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10

Hay, M. P. "Atom transfer reactions of amino acid derivatives." Thesis, University of Canterbury. Chemistry, 1987. http://hdl.handle.net/10092/7974.

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Investigations of atom transfer reactions of amino acid derivatives are described in this thesis. Reaction of N-benzoylvaline methyl ester (29a) with sulphuryl chloride gave the β-chlorovaline derivative (30a) and lesser amounts of diastereoisomers of the r-chlorovaline derivative (31a). Studies of reactions of the valine derivatives (29a-c) with sulphuryl chloride, and of the photolyses of the corresponding N-chlorovaline derivatives (39a-c) have shown that the reaction of (29a) with sulphuryl chloride and the photolysis of (39a) involve regioselective intermolecular transfer of the respectiv
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11

Sanganee, Mahesh Jayantilal. "Synthesis of novel-functionalized phosphinic acid derivatives." Thesis, London Metropolitan University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.391909.

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12

Peron, Guillaume Luc Nicolas. "Lewis acid mediated cyclisation of methylenecyclopropane derivatives." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326304.

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13

Sun, Jing. "Synthesis and Application of Boronic Acid Derivatives." Thesis, Virginia Tech, 2010. http://hdl.handle.net/10919/77006.

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Boronic acids are attractive synthetic intermediates and have been shown to be effective as inhibitors of various enzymes. In this project, the overarching goal is the selective inhibition of a protease present in the mitochondria known as human ClpXP. To study the potential selective inhibition of Human ClpXP using N-terminal peptidic boronic acid, we have designed a synthetic scheme that includes?-borylation of °,?-unsaturated carbonyl compounds using Cu(I) as catalyst, °-alkylation, saponification/hydrogenation, amidation, and oxidative removal of pinacolyl group with sodium periodate. A s
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14

Volckman, Janis F. "The synthesis of fungicidal aminophosphonic acid derivatives." Thesis, London Metropolitan University, 1988. http://repository.londonmet.ac.uk/3425/.

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A number of 1-aminoalkanephosphonic acid derivatives incorporating physiologically Iabile groupings (ester, amide e.g. peptide, carbamate and tosyl) were prepared as a development from earlier studies in which certain phosphonic acid derivatives were shown to have previously unrecognised activity as fungicides. Such derivatisation might aid the translocation of the active phosphonic acid to the site of action. Compounds were screened for in vivo fungicidal activity against Drechslera teres. Drechslera graminae. Drechslera avenae. Prythium ultlmum. Rhizoctonia solani. Fusarium culmorum. Pyricul
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15

Feuillet, Frederic. "Stereoselective synthesis of (E)-trisubstituted acid derivatives." Thesis, University of Bath, 2004. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.397111.

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16

Nguyen, Dao. "SYNTHESIS OF A NOVEL FAMILY OF AMIDE DERIVATIVES OF PODOCARPIC ACID." Master's thesis, University of Central Florida, 2004. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/2221.

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As a class, amides are of great interest in biological studies and pharmaceutical application. In this work, podocarpic acid, a natural tricyclic diterpene, derived from Podocarpus species, has been employed to form a novel family of amide derivatives which will later be studied for their potential as new drug leads. Novel amide derivatives of podocarpic acid were synthesized from podocarpic acid in three steps. The first step involved methylation with dimethylsulfate to form methyl-O-methylpodocarpate. This step was followed by iodination with iodine to give iodomethyl-O-methylpodocarpate. Fi
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17

Nascimento, PatrÃcia Georgina Garcia do. "Obtaining of derivatives lithocholic acid and antimicrobial activity." Universidade Federal do CearÃ, 2012. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=16720.

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CoordenaÃÃo de AperfeÃoamento de Pessoal de NÃvel Superior<br>This paper describes obtaining eight lithocholic acid derivatives, as well as inhibitory activity. Interest in the use of lithocholic acid as starting material for the preparation of derivatives arose because of it being widely studied in order to discover new biological activities and such studies have shown good results. In this work it was used for the synthesis of a series of derivatives with modifications at the C-3 and/or C-24 of the steroid skeleton. The series was prepared using simple chemical and showed good yields. Aiming
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18

Schult, Tove. "Properties of acid sulfite cellulose for cellulose derivatives." Doctoral thesis, Norwegian University of Science and Technology, Department of Chemical Engineering, 2000. http://urn.kb.se/resolve?urn=urn:nbn:no:ntnu:diva-1508.

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19

Motto, John M. "Ã,ß-unsaturated sulfoxides and sulfinic acid derivatives." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2001. http://www.collectionscanada.ca/obj/s4/f2/dsk3/ftp04/MQ58363.pdf.

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20

Rhoden, Stephen. "SYNTHESIS OF NOVEL AZIRIDINE DERIVATIVES OF PODOCARPIC ACID." Master's thesis, University of Central Florida, 2007. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/3569.

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Podocarpic acid (a diterpenoid resin acid extracted from the Podocarpacea specie of plants) has shown cytotoxicity against carcinoma of the nasopharynx. Since this discovery has been made, research has been performed in order to alter the structure of the resin acid so as to increase the anticancer activity. The carboxylic acid and phenol functional groups, which are present in podocarpic acid, make it possible to synthesize new derivatives selectively at the C-15, C-13, and C-7 positions as well as by substitution of the phenol hydroxyl group. Thus numerous derivatives can be prepared, in hig
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21

Brown, Samantha Jayne. "Novel fluorinated succinic acid derivatives from HCFC-133a." Thesis, University of Birmingham, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.396808.

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22

Masesane, Ishmael Baperi. "Stereoselective routes to cyclic β-amino acid derivatives". Thesis, Durham University, 2003. http://etheses.dur.ac.uk/3700/.

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The literature structure of the natural product oryzoxymycin and an array of 3-mono-,3,4-di- and 3,4,5-tri-hydroxylated derivatives of 2-aminocyclohexane-l-carboxyhc acid (ACHC) were stereoselectively prepared from oxanorbomene adducts derived from the Diels Alder reaction of ethyl (E)-3-nitroacrylate and furan. The central reaction for these syntheses was the base mediated β-elimination of the oxygen bridge of the oxanorbomene adducts or their derivatives. The asymmetnc synthesis of the literature structure of oryzoxymycin involved chiral HPLC or enzyme catalysed kinetic resolution of the end
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23

Abraham, Ffion. "Fluorinated benzylphosphonic acid derivatives for work function modification." Thesis, Durham University, 2014. http://etheses.dur.ac.uk/10622/.

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Methodology for the synthesis of polyfluorinated biphenyl benzylphosphonic acids was developed and various highly fluorinated phosphonic acid derivatives may be synthesised from the corresponding fluorobenzene system. Synthesis of analogous benzylphosphonic acids from corresponding benzyl bromides is also described. The use of these systems as self-assembled monolayers on AlOx was assessed by a range of surface-sensitive analytical techniques. The surface energy and work function of aluminium oxide (AlOx) may be altered upon the adsorption of monolayers formed of partially fluorinated benzylph
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24

Smith, David John. "Complexation of amino-acid derivatives using macrocyclic receptors." Thesis, University of Bath, 1996. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319219.

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25

Miles, Andrew. "Copolymers of methacrylic acid and itaconic acid derivatives as thermally crosslinkable electron resists." Thesis, University of Stirling, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236050.

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26

Mahajan, Anju. "Chemistry of 4-azalysine and its derivatives." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324756.

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27

Karanjai, Manju. "Organotin derivatives of carbonyl activated unsaturated organic compounds and their Lewis acid characters." Thesis, University of North Bengal, 1989. http://hdl.handle.net/123456789/765.

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28

Wiklund, Per. "Synthesis of heterocycles from anthranilic acid and its derivatives /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-913-7/.

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29

Ng, S. C. "Enzymatic and non enzymatic synthesis of amino acid derivatives." Thesis, University of Oxford, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379948.

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30

Kausar, Nighat. "Experimental spectroscopic and theoretical studies of amino acid derivatives." Thesis, University of Greenwich, 2008. http://gala.gre.ac.uk/6207/.

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Experimental vibrational/electronic circular dichroism spectroscopic and theoretical studies of amino acid derivatives, i.e. N-acetyl-L-Asp, N-acetyl-L-Glu, and di-amino acid peptide/derivatives, i.e. L-Asp-L-Glu, a-N-acetyl-L-Asp-L-Glu, and ß-N-acetyl-L-Asp-L-Glu are reported. The calculated structures for N-acetyl-L-Asp and N-acetyl-L-Glu differ. The conformation of the trans amide moiety changes with the carbon chain length of the side chain of the amino acid derivatives. In the computed structures of N-acetyl-L-Asp and N-acetyl-L-Glu all backbone atoms are in-plane, except the side chain g
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31

Shepherd, Emma J. "The development of enantioselective receptors for amino acid derivatives." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343011.

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32

Clare, Joanna Elizabeth. "The synthesis and applications of 4-nitrobutanoic acid derivatives." Thesis, University of Bristol, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.419207.

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33

Owston, Nathan Ashley. "Novel transition metal-catalysed syntheses of carboxylic acid derivatives." Thesis, University of Bath, 2008. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512253.

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This thesis describes the chemistry developed during a study of novel transition metalcatalysed reactions for the synthesis of carboxylic acid derivatives. Chapter 2 describes a novel protocol for the synthesis of primary amides from alcohols in one-pot where a metal complex mediates two fundamentally different catalytic processes. An iridium catalyst has been shown to be effective for the selective rearrangement of aldoximes into primary amides. In addition, an iridium-catalysed oxidation of activated alcohols via hydrogen transfer has been developed using an alkene as formal oxidant. These r
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34

Conley, Matthew. "Supercritical Water Gasification of Two-Carbon Carboxylic Acid Derivatives." Ohio University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1542202432022198.

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35

St, Claire Green Donovan. "The synthesis of aminophosphonic acid derivatives & related compounds." Thesis, London Metropolitan University, 1991. http://repository.londonmet.ac.uk/3256/.

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1-Aminoalkanephosphonic acids and their derivatives, have long been claimed to be compounds with a wide variety of application. Numerous examples exist where they have been described as: complex-forming agents with sequestrating properties, extractants, wetting agents, pharmaceutical preparations, ion exchangers, herbicides, compounds with plant growth regulatory activity; inhibitors of aminopeptidases; as structural units in peptide analogues, functioning as antibacterial agents, which inhibit bacterial cell wall biosynthesis; as structural units in peptidic phosphonylating agents that irreve
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36

Parker, Rebecca J. "Dynamic kinetic resolution of α-substituted carboxylic acid derivatives". Thesis, University of Bath, 2001. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.392210.

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37

Mas-Roselló, Josep. "C-arylation and alkenylation of α-amino acid derivatives". Thesis, University of Bristol, 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738542.

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38

Stanley, Mathew. "Sialic acid derivatives and mimetics : tools for the investigation of sialic acid processing enzymes." Thesis, University of Sussex, 2011. http://sro.sussex.ac.uk/id/eprint/7415/.

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I. Synthesis and inhibitory activity of sialic acid derivatives targeting viral sialate-O-acetylesterases and sialate-O-acetyltransferases Sialate-O-acetylation is a common structural modification of sialic acid, which has been associated with many human disease states (including cancer and autoimmune disease). This highly regulated and tissue-specific modification is carried out by sialate- O-acetylesterase (SOAE) and sialate-O-acetyltransferase (SOAT) enzymes. The availability of these enzymes make inhibition studies a viable endeavour, considering that SOAT/SOAE inhibitors may provide inter
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39

Carter, James. "A New Synthetic Pathway Towards Legionaminic Acid." Thesis, Griffith University, 2018. http://hdl.handle.net/10072/381511.

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This thesis describes the results of a PhD project aimed at researching a new synthetic pathway towards legionaminic acid analogues. Legionaminic acid is a bacterial family of nonulosonic acids expressed in a terminal position on the flagellar glycans and are considered to be a virulence factor in the pathogenic bacteria that possess them. At the outset of this project several examples of Leg synthesis had been published. Whilst three syntheses of Leg derivatives have been published while the research described in this thesis was being carried out, the potential of all the published syntheses
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40

Brian, King Himm Mo. "Biochemical analysis and genetic engineering of oleaginous fungi for the production of eicosapentaenoic acid and free fatty acid derivatives." Doctoral thesis, Kyoto University, 2021. http://hdl.handle.net/2433/263714.

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41

Tommey, Tyler. "Synthesis and Characterization of Free-acid Derivatives and Corresponding Ionomers of Poly(L-lactic acid)." University of Akron / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=akron1596234685966831.

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42

Murota, Kaeko. "INHIBTION OF DIETARY FATTY ACID ABSORPTION BY EXOGENOUS FATTY ACID DERIVATIVES IN THE SMALI INTESTINE." Kyoto University, 2001. http://hdl.handle.net/2433/150341.

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43

McNichols, Brett William. "Synthesis and Application of Styryl Phosphonic and Cinnamic Acid Derivatives." Thesis, Colorado School of Mines, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10624231.

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<p> Styryl phosphonic and cinnamic acid derivatives have been gaining attention as key candidates to modulate specific electrode properties in organic electronic devices such as work function, surface energies, wettability, and electron charge transfer kinetics that lead to increased efficiency, operational range, and device lifetimes. Very few of these acids are commercially available. The driving factor behind this research is to explore simple, high yield, and inexpensive synthetic routes towards synthesis of these acids. Herein, the novel synthesis of vinyl phosphonic acids (VPAs) and thei
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44

Mayr, Norbert. "Energetic materials based on isocyanuric acid and 1,2,4-oxadiazole derivatives." Diss., Ludwig-Maximilians-Universität München, 2013. http://nbn-resolving.de/urn:nbn:de:bvb:19-162379.

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The synthesis and properties of explosive urea and triazine derivatives is investigated on behalf of the explosive parameters and the full characterization of the molecules. (Chapter I-III) The class of oxadiazole derivatives is enhanced from the known explosive 1,2,5 oxadiazole (furazane) derivatives to the 1,2,4 oxadiazole derivatives. This molecule class is thoroughly investigated by all terms of chemical and explosive material matter and especially the 1,2,4-oxadiazol-5-one derivatives are compared to the corresponding tetrazole derivatives which were by far the most investigated molecule
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45

Bauer, Julia. "Synthesis of sialic acid derivatives and their incorporation into microarrays." Thesis, University of Reading, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603523.

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46

Smith, Peter Duncan. "Synthesis of pipecolic acid derivatives via aza-Diels-Alder reactions." Thesis, Heriot-Watt University, 2000. http://hdl.handle.net/10399/552.

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47

Bassin, Jatinder Paul. "Chlorosulphonic acid in heterocyclic synthesis-cyclic sulphones and ketoarylidene derivatives." Thesis, University of Hertfordshire, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303497.

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48

Wang, Yulan. "Spectroscopic studies of solid amino acid derivatives and their mixtures." Thesis, University of East Anglia, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.389201.

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49

Evans, Lyndsay Ann. "Synthesis of hydroxy and amino acid derivatives using stereoselective epoxidation." Thesis, University of Sheffield, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.425618.

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50

Garrido, Neil. "The asymmetric synthesis of α- and β-amino acid derivatives." Thesis, University of Reading, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428296.

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