Academic literature on the topic 'Acide pyrazolique'

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Journal articles on the topic "Acide pyrazolique"

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El Mahdi, O., J. P. Lavergne, P. H. Viallefont, and M. Akssira. "SYNTHESE D'AMINO ACIDES PYRAZOLIQUES." Bulletin des Sociétés Chimiques Belges 104, no. 1 (2010): 31–37. http://dx.doi.org/10.1002/bscb.19951040107.

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Hajalsiddig, Tawassl Tajelsir Hassan, and Ahmed Elsadig Mohammed Saeed. "Synthesis of new 6-substituent 2-phenyl and 2-(furan-2-yl)-3-phenyl-quinoline-4-carboxylic acid derivatives." European Journal of Chemistry 10, no. 1 (2019): 57–63. http://dx.doi.org/10.5155/eurjchem.10.1.57-63.1816.

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A synthesis of substituted quinolines has been achieved by the Doebner reaction which is a three component coupling of arylaldehyde, p-amino-acetophenone and phenyl pyruvic acid. The products of 2,3-diary-6-acetyl-quinoline-4-carboxylic acids were obtained by Claisen Schmidt condensation reaction with aldehydes in the presence of sodium hydroxide in order to give the corresponding α,β-unsaturated carbonyls. The substituted α,β-unsaturated carbonyls were condensed with urea, thiourea, hydrazine, phenyl hydrazine, semicarbazide hydrochloride and ethanolamine to synthesized 2-pyrimidinone, 2-pyri
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KANG, YOUNG SOO, SUN WHA OH, and JONG HWA SUH. "PREPARATION AND CHARACTERIZATION OF ORGANIC THIN FILM OF STEARIC ACID/PYRAZOLINE NANOPARTICLES." International Journal of Nanoscience 05, no. 02n03 (2006): 199–205. http://dx.doi.org/10.1142/s0219581x06004243.

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The organic thin films of stearic acid/pyrazoline nanoparticles were prepared by transferring Langmuir monolayer of stearic acid/pyrazoline nanoparticle onto the solid substrate. The complex of stearic acid/pyrazoline nanoparticle was studied with pressure–area isotherm at the air/water interface and identified with linearly increasing optical absorbance around 370 nm by increasing the number of deposited layers. The in situ domain structure and molecular orientation of the complex were measured with BAM. The surface morphology of the Langmuir–Blodgett film was observed with AFM. The dispersio
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Nurlaili, Jasril, and Hilwan Yuda Teruna. "UJI AKTIVITAS ANTIOKSIDAN SENYAWA PIRAZOLIN 3-(2- METOKSI-FENIL)-5-NAFTALEN-1-IL-4,5-DIHIDRO-1H-PIRAZOL." Photon: Jurnal Sain dan Kesehatan 8, no. 2 (2018): 53–58. http://dx.doi.org/10.37859/jp.v8i2.716.

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Pyrazoline compounds are reported to have many useful biological activities such as antimicrobials, antihyperglycemia, antioxidants, anti-inflammatory, anticancer and anticonvulsants. The pyrazoline analogues of 3- (2-methoxy-phenyl) -5-naphthalene-1-yl-4,5-dihydro-1H-pyrazol were synthesized usingglacial acetic acid as catalyst and assisted by microwave irradiation. The structures of the compounds were obtainedby UV, IR and HRMS spectroscopy data. Antioxidant activity test using DPPH method showed that pyrazoline compound had IC50 value of 27.41 μg/mL.
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Park, Sang Won, Soong-Hyun Kim, Jaeyoung Song, et al. "Hypervalent iodine-mediated Ritter-type amidation of terminal alkenes: The synthesis of isoxazoline and pyrazoline cores." Beilstein Journal of Organic Chemistry 14 (May 11, 2018): 1028–33. http://dx.doi.org/10.3762/bjoc.14.89.

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Hypervalent iodine-mediated olefin functionalization provides a rapid gateway towards accessing both various heterocyclic cores and functional groups. In this regard, we have developed a Ritter-type alkene functionalization utilizing a PhI(OAc)2 ((diacetoxyiodo)benzene, PIDA)/Lewis acid combination in order to access isoxazoline and pyrazoline cores. Based on allyl ketone oximes and allyl ketone tosylhydrazones, we have developed an alkene oxyamidation and amido-amidation protocol en route to accessing both isoxazoline and pyrazoline cores. Additionally, acetonitrile serves as both the solvent
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Sultan, Mohammed Ibrahim, Ahmed M. Abdula, Rana I. Faeq, and Mahdi F. Radi. "New Pyrazoline Derivatives Containing Imine Moiety: Synthesis, Characterization and Antimicrobial Study." Al-Mustansiriyah Journal of Science 32, no. 3 (2021): 8. http://dx.doi.org/10.23851/mjs.v32i3.955.

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A new series of pyrazoline derivatives (3-10) have been synthesized and characterized on the basis of FT-IR, 1H-NMR, and Mass techniques. 1-(4-Aminophenyl)-3-(pyridin-4-yl)prop-2-en-1-one (1) as a starting material was prepared by the reaction of 4-aminoacetophenone and 4-pyridinecarboxaldehyde in ethanol, using sodium hydroxide as a catalyst. Pyrazoline derivatives 2 was obtained via the cyclization reaction of compound 1 by the action of hydrazine hydrate 80% in ethanol. The target derivatives (3-8) were obtained by the reaction of pyrazoline derivative (2) with the corresponding aldehyde in
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Guo, Shengmei, Yuyang Zhang, Jianyan Huang, Lin Kong, and Jiaxiang Yang. "High dual-state blue emission of a functionalized pyrazoline derivative for picric acid detection." CrystEngComm 23, no. 1 (2021): 221–26. http://dx.doi.org/10.1039/d0ce01195a.

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Maleki, Behrooz, Davood Azarifar, Khodaverdian Moghaddam, Fatemeh Hojati, Mostafa Gholizadeh, and Hafezeh Salehabadi. "Synthesis and characterization of a series of 1,3,5-trisubstituted-2-pyrazolines derivatives using methanoic acid under thermal condition." Journal of the Serbian Chemical Society 74, no. 12 (2009): 1371–76. http://dx.doi.org/10.2298/jsc0912371m.

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An efficient and practical synthesis of 1,3,5-trisubstituted 2-pyrazoline structures was achieved through cyclization of phenylhydrazine with ?,? -unsaturated ketones (chalcones) using methanoic acid (formic acid) as catalyst under thermal condition.
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Daneshfar, Zahra, and Ali Rostami. "Cellulose sulfonic acid as a green, efficient, and reusable catalyst for Nazarov cyclization of unactivated dienones and pyrazoline synthesis." RSC Advances 5, no. 127 (2015): 104695–707. http://dx.doi.org/10.1039/c5ra19773b.

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Lohidakshan, Krishnakumar, Manju Rajan, Andhale Ganesh, Mathew Paul, and Jithu Jerin. "Pass and Swiss ADME collaborated in silico docking approach to the synthesis of certain pyrazoline spacer compounds for dihydrofolate reductase inhibition and antimalarial activity." Bangladesh Journal of Pharmacology 13, no. 1 (2018): 23. http://dx.doi.org/10.3329/bjp.v13i1.33625.

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<p class="Abstract">New series of pyrazoline spacer compounds were prepared by the reaction between benzimidazole chalcones and (2-methyl-5-nitro-imidazole-1-yl)-acetic acid hydrazide by the sensible use of Michael addition. The building blocks used for the synthesis of pyrazoline derivatives were opted by using virtual screening by molinspiration search engine. The hypothetically resulted pyrazoline spacer compounds from this list are checked for their reliability on other in silico drug designing online web services like PASS online bioactivity, Swiss ADME predictor. The docking study
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Dissertations / Theses on the topic "Acide pyrazolique"

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Voss, Emelyne. "Synthèse d’Analogues Bis-azotés de la Proline et Applications." Thesis, Vandoeuvre-les-Nancy, INPL, 2011. http://www.theses.fr/2011INPL059N/document.

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La liaison peptidique au sein d’un peptide ou d’une protéine est d’ordinaire plane et en conformation trans pour la majorité des acides aminés. La situation est un peu différente en amont d’une proline : la barrière thermodynamique qui s’oppose à la rotation de la liaison amide est plus faible et la tendance de la liaison à rester plane est un peu moins grande. Cette liaison AA-Pro peut donc adopter une conformation cis, entraînant la formation d’un coude prononcé dans une chaîne peptidique à son niveau. Ce travail décrit la synthèse et la réactivité chimique de nouveaux analogues bis-azotés d
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Seager, Laura Elizabeth. "Cycloaddition routes to pyrazole and pyrazoline amino acids." Thesis, Loughborough University, 2009. https://dspace.lboro.ac.uk/2134/34835.

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In recent years, the design and synthesis of structures that can potentially mimic the properties of the peptide bond have been of great interest to biological chemists. We are investigating the synthesis of novel pyrazoline-based structures as potential peptide mimetics. The pyrazoline unit is assembled by 1,3-dipolar cycloaddition of nitrile imines, which are generated in situ from hydrazonyl chlorides. We have investigated two routes to afford the hydrazonyl chloride, (1) via a hydrazone and (2) via a hydrazide, both of which have resulted in the successful synthesis of the desired pyrazoli
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El, Mahdi Ouafâa. "Synthèse de cyclodipeptides à sept chaînons à partir de "Bêta"-aminoacides pyrazoliques et de "Bêta"-aminoacides fonctionnalisés." Montpellier 2, 1997. http://www.theses.fr/1997MON20162.

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Le but de ce travail est la mise au point de nouveaux cyclodipeptides a sept chainons. Dans une premiere partie, nous decrivons la synthese de pyrazolodiazepinediones en deux etapes a partir de -aminoacides pyrazoliques. Les dipeptides lineaires issus du couplage de ces aminoacides avec des -aminoesters sont cyclises dans de bonnes conditions par action de l'ethylate de sodium. Nous presentons dans une seconde partie une synthese originale de cyclodipeptides fonctionnalises, susceptibles d'etre integres dans des peptides bioactifs. Apres de multiples tentatives, nous avons pu cycliser les dipe
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Chen, Kuan Ju, and 陳冠如. "Lipase-catalyzed methanolytic resolution of (R,S)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-(2-pyridyl)pyrazolide in organic solvents." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/71083762747828481323.

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碩士<br>長庚大學<br>生化與生醫工程研究所<br>100<br>The purpose of this research is aimed to investigate effects of different lipases on the kinetic resolution of (R,S)-pyrrolidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-(2-pyridyl)pyrazolide in anhydrous organic solvents. Experiments were first performed to screen different lipases from Novo435, Lipase MY, and Lipase PS-D, different temperature, and organic solvents from anhydrous methyl tert-butyl ether (MTBE), cyclohexane (CYC), diisopropylether (IPE), and isooctane (ISO). The best methanolytic reaction condition of using Novo435 in anhydrous MTBE at 45℃
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