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Relevant bibliographies by topics / Acremonium chrysogenum

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Academic literature on the topic 'Acremonium chrysogenum'

Author: Grafiati

Published: 4 June 2021

Last updated: 18 February 2022

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Journal articles on the topic "Acremonium chrysogenum"

1

Stepanov, Valentin M., Galina N. Rudenskaya, Lyudmila I. Vasil'eva, Irina N. Krest'anova, Olga M. Khodova, and Yurii E. Bartoshevitch. "Serine proteinases from Acremonium chrysogenum." International Journal of Biochemistry 18, no. 4 (January 1986): 369–75. http://dx.doi.org/10.1016/0020-711x(86)90043-1.

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2

Kozma, J�zsef, Luz Lucas, and Karl Sch�gerl. "Alternative respiration of Acremonium chrysogenum." Biotechnology Letters 13, no. 12 (December 1991): 899–900. http://dx.doi.org/10.1007/bf01022095.

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3

Bartoshevich, Yu E., P. L. Zaslavskaya, M. J. Novak, and O. D. Yudina. "Acremonium chrysogenum differentiation and biosynthesis of cephalosporin." Journal of Basic Microbiology 30, no. 5 (1990): 313–20. http://dx.doi.org/10.1002/jobm.3620300503.

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4

Aldana Bohórquez, Sandra Milena, and Ramón Ovidio García-Rico. "Effect of different stress conditions on the vegetative growth of the filamentous fungus Acremonium chrysogenum." BISTUA REVISTA DE LA FACULTAD DE CIENCIAS BASICAS 17, no. 2 (August 16, 2019): 182. http://dx.doi.org/10.24054/01204211.v2.n2.2019.3535.

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El hongo filamentoso Acremonium chrysogenum produce una mezcla de sustancias antibióticas, entre las que destaca la cefalosporina C. Con una participación de mercado del 50% para la cefalosporina C y sus derivados semisintéticos, desempeñan un importante rol en la industria farmacéutica. Debido a su amplio espectro de efectividad contra las bacterias Gram (+) y Gram (-), la cefalosporina C es un fármaco importante, producido únicamente por A. chrysogenum. Las condiciones ambientales inducen adaptaciones en los seres vivos, que responden modificando sus procesos biológicos para lograr su supervivencia. Estas respuestas pueden evaluarse in vitro para dilucidar el efecto del estrés fisiológico en el desarrollo. De esta manera, en este trabajo se evaluó el efecto de diferentes osmolitos, del peróxido de hidrógeno y la luz blanca sobre el crecimiento vegetativo de A. chrysogenum. Se observó un incremento del crecimiento de A. chrysogenum en condiciones de NaCl 0,5 M, mientras que frente al KCl fue osmosensible, deduciéndose una osmoadaptación al NaCl. El glicerol solamente mostró efectos inhibidores del crecimiento a concentraciones de 1M. Por otro lado, A. chrysogenum presentó tolerancia al estrés oxidativo inducido por el peróxido, incluso a concentraciones de 100 mM. Finalmente, un fotoperíodo LD (12/12) estimuló el desarrollo del hongo, mientras que en condiciones LL la tasa de crecimiento fue similar a la observada en la condición de control (DD).Palabras clave: Acremonium chrysogenum, estrés osmótico, estrés oxidativo, estrés lumínico.

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5

Pï¿½ggeler, Stefanie, Birgit Hoff, and Ulrich Kï¿½ck. "Asexual Cephalosporin C Producer Acremonium chrysogenum Carries a Functional Mating Type Locus." Applied and Environmental Microbiology 74, no. 19 (August 8, 2008): 6006–16. http://dx.doi.org/10.1128/aem.01188-08.

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ABSTRACT Acremonium chrysogenum, the fungal producer of the pharmaceutically relevant β-lactam antibiotic cephalosporin C, is classified as asexual because no direct observation of mating or meiosis has yet been reported. To assess the potential of A. chrysogenum for sexual reproduction, we screened an expressed sequence tag library from A. chrysogenum for the expression of mating type (MAT) genes, which are the key regulators of sexual reproduction. We identified two putative mating type genes that are homologues of the α-box domain gene, MAT1-1-1 and MAT1-1-2, encoding an HPG domain protein defined by the presence of the three invariant amino acids histidine, proline, and glycine. In addition, cDNAs encoding a putative pheromone receptor and pheromone-processing enzymes, as well as components of a pheromone response pathway, were found. Moreover, the entire A. chrysogenum MAT1-1 (AcMAT1-1) gene and regions flanking the MAT region were obtained from a genomic cosmid library, and sequence analysis revealed that in addition to AcMAT1-1-1 and AcMAT1-1-2, the AcMAT1-1 locus comprises a third mating type gene, AcMAT1-1-3, encoding a high-mobility-group domain protein. The α-box domain sequence of AcMAT1-1-1 was used to determine the phylogenetic relationships of A. chrysogenum to other ascomycetes. To determine the functionality of the AcMAT1-1 locus, the entire MAT locus was transferred into a MAT deletion strain of the heterothallic ascomycete Podospora anserina (the PaΔMAT strain). After fertilization with a P. anserina MAT1-2 (MAT+) strain, the corresponding transformants developed fruiting bodies with mature ascospores. Thus, the results of our functional analysis of the AcMAT1-1 locus provide strong evidence to hypothesize a sexual cycle in A. chrysogenum.

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6

Martı́n, Juan F., and Arnold L. Demain. "Unraveling the methionine–cephalosporin puzzle in Acremonium chrysogenum." Trends in Biotechnology 20, no. 12 (December 2002): 502–7. http://dx.doi.org/10.1016/s0167-7799(02)02070-x.

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7

Zhgun, A. A., M. A. Ivanova, A. G. Domracheva, M. I. Novak, M. A. Elidarov, K. G. Skryabin, and Yu E. Bartoshevich. "Genetic transformation of the mycelium fungi Acremonium chrysogenum." Applied Biochemistry and Microbiology 44, no. 6 (October 28, 2008): 600–607. http://dx.doi.org/10.1134/s0003683808060070.

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8

Karaffa, Levente, Erzsébet Sándor, Erzsébet Fekete, József Kozma, Attila Szentirmai, and István Pócsi. "Stimulation of the cyanide-resistant alternative respiratory pathway by oxygen in Acremonium chrysogenum correlates with the size of the intracellular peroxide pool." Canadian Journal of Microbiology 49, no. 3 (March 1, 2003): 216–20. http://dx.doi.org/10.1139/w03-029.

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The relationship between oxygen input and activity of the cyanide-resistant alternative respiration of submerged cultures of Acremonium crysogenum was investigated. The volumetric oxygen transfer coefficient of the respective cultures correlated positively within almost two ranges of magnitude with the size of the intracellular peroxide pool, which in turn, correlated with the activity of the cyanide-resistant alternative respiratory pathway. Increased aeration also stimulated the glucose uptake rate but had no effect on the total respiration rate or the growth rate. Addition of the lipid peroxyl radical scavenger DL-α-tocopherol to A. chrysogenum cultures decreased the rate of intracellular peroxide production as well as glucose uptake. An increase in the cyanide-resistant fraction of total respiration was observed, while growth and the total respiratory activity remained unchanged. We conclude that intracellular peroxides may stimulate the alternative respiration in A. chrysogenum.Key words: Acremonium chrysogenum, alternative respiration, oxygen, peroxide, Kla.

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9

Luengo, J. M., M. T. Alemany, F. Salto, F. Ramos, M. J. López-Nieto, and J. F. Martin. "Direct Enzymatic Synthesis of Penicillin G Using Cyclases of Penicillium chrysogenum and Acremonium chrysogenum." Nature Biotechnology 4, no. 1 (January 1986): 44–47. http://dx.doi.org/10.1038/nbt0186-44.

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10

Jekosch, K., and U. Kück. "Codon bias in the ß-lactam procucer Acremonium chrysogenum." Fungal Genetics Reports 46, no. 1 (July 25, 1999): 9–10. http://dx.doi.org/10.4148/1941-4765.1233.

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Dissertations / Theses on the topic "Acremonium chrysogenum"

1

Hauck, Katarzyna. "Transposonen und Regulation der Genexpression bei den Antibiotika-produzierenden Pilzen Penicillium chrysogenum und Acremonium chrysogenum /." Berlin : J. Cramer, 2002. http://catalogue.bnf.fr/ark:/12148/cb39136547w.

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2

Pfeil, Michael. "Funktionsanalyse und molekulare Charakterisierung der bifunktionalen Expandase/Hydroxylase aus dem Hyphenpilz Acremonium chrysogenum /." Berlin : J. Cramer, 2001. http://catalogue.bnf.fr/ark:/12148/cb413088755.

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3

Smith, Andrew W. "The isopenicillin N synthetase (IPNS) gene (pcbC) : promotor of Acremonium chrysogenum." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.258234.

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4

Vialta, Airton. "Genetica e produção de cefalosporina C na linhagem C-10 de Acremonium chrysogenum." [s.n.], 1994. http://repositorio.unicamp.br/jspui/handle/REPOSIP/316874.

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Orientador: João Lucio de Azevedo
Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia
Made available in DSpace on 2018-07-19T15:48:28Z (GMT). No. of bitstreams: 1 Vialta_Airton_D.pdf: 7068425 bytes, checksum: 35be95d571d938d79e669c7ef9161e46 (MD5) Previous issue date: 1994
Doutorado
Doutor em Genetica

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5

Kimura, Hiroyuki. "Cephalosporin biosynthetic genes and their application to the strain improvement of Acremonium chrysogenum." Kyoto University, 2002. http://hdl.handle.net/2433/150375.

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6

Whitehead, Michael Phillip. "Development of homologous transformation systems for the filamentous fungi 'Cephalosporium acremonium' and 'Penicillium chrysogenum'." Thesis, University of St Andrews, 1991. http://hdl.handle.net/10023/14259.

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Spontaneous chlorate resistant mutants of Penicillium chrysogenum and Cephalosporium acremonium have been isolated. Putative genotypes of the P. chrysogenum mutants were identified using the phenotypic characterization of Cove (1979). This analysis was also attempted with C. acremonium, however it was found that the wild type organism could not grow on minimal media containing glucose and hypoxanthine and thus cnx and niaD mutants could not be differentiated using this method. Following the distinction of cnx and niaD mutants using cytochrome C reductase and purine hydroxylase I assays, a simple plate test using minimal media containing quinic acid as carbon source and inosine as nitrogen source was developed to analyse cnx and niaD mutants. Nonreverting (at less than 1 in 108) niaD mutants were isolated for later experiments. P. chrysogenum niaD mutant niaD19 was transformed to nitrate utilization at a frequency of up to 20 transformants/mug DNA using the Aspergillus nidulans niaD gene, up to nine/mug DNA with the A. niger niaD gene and up to three/mug DNA using the A. oryzae niaD gene. Vector constructs carrying the A. nidulans ans-1 sequence with the A niger niaD gene did not show increased transformation efficiency. Linearization of the A. niger niaD containing plasmid resulted in a two to three times increase in transformation frequency. Southern blot hybridization analysis demonstrated that vector sequences had integrated into the recipient genome. The control of heterologous niaD gene expression generally agreed with that found in the wild type strain, that is, induction by nitrate and repression in the presence of ammonium. The A. nidulans, A. niger and A. oryzae genes failed to transform C. acremonium niaD mutants. A DNA fragment containing the C. acremonium niaD gene was isolated by cross hybridization to the A. nidulans niaD gene. This fragment was sub-cloned into pUC18 (designated pSTA700), and showed back hybridization to C. acremonium wild type DNA exhibiting the expected hybridization pattern. When partially sequenced, it showed nucleotide and determined amino acid homology to the A. nidulans niaD gene and protein. The clone pSTA700 transformed a C. acremonium niaD mutant, CSG116 and P. chrysogenum STP19 to nitrate utilization at a frequency of up to 47 and six transformants/mug DNA, respectively. When heat shock was applied to C. acremonium protoplasts 10mins prior to the addition of DNA, transformation frequencies of up to 137/mug DNA were obtained. Southern analysis of transformants revealed multiple integration of vector sequences, with no detectable preference for the homologous niaD site. Some C. acremonium transformants showed a greatly increased nitrate reductase activity (up to 10 times wild type activity) when induced with nitrate. The niaD transformation system was successfully used to introduce unselected markers into C. acremonium such as hygromycin B and benomyl resistance. The co-transformation frequency was up to 25% when equal molar ratios of plasmids were used. Antibiotic biosynthetic genes isolated from C. acremonium (pcbC and cefEF) and A. nidulans (pcbC and penE) were introduced into C. acremonium CSG116 by co-transformation with the C. acremonium niaD gene or the construction of vectors containing both the C. acremonium niaD gene and antibiotic biosynthetic genes. Isolates transformed with the C. acremonium pcbC and cefEF genes exhibited an increase in antibacterial activity (greater than 20% compared to wild type) at frequencies of up to 10% and six percent of transformants, respectively. When A. nidulans constructs containing the pcbC and penE genes, but not the pcbC gene alone, were co-transformed into C. acremonium, up to 18% of transformants exhibited an increase in antibacterial activity. The presence of penicillin antibiotics could not be found in these transformants and thus the exact cause of this increase in antibacterial activity could not be determined.

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7

Seidel, Guido. "Kultivierungen mit einem Hochleistungsstamm von Acremonium chrysogenum in komplexen und synthetischen Medien Strategien zur Produktivitätssteigerung unter Berücksichtigung der Enzymaktivitäten der Cephalosporin-C-Biosynthese /." [S.l. : s.n.], 1999. http://deposit.ddb.de/cgi-bin/dokserv?idn=962098469.

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8

Löper, David [Verfasser], Ulrich [Gutachter] Kück, and Nicole [Gutachter] Frankenberg. "DNA-bindende Proteine des Antibiotika-Produzenten Acremonium chrysogenum : biochemische Charakterisierung und molekulargenetische Funktionsanalysen / David Löper ; Gutachter: Ulrich Kück, Nicole Frankenberg ; Fakultät für Biologie und Biotechnologie." Bochum : Ruhr-Universität Bochum, 2012. http://d-nb.info/1240476051/34.

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9

Kluge, Janina Verfasser], Ulrich [Gutachter] Kück, and Dominik [Gutachter] [Begerow. "Multicellular development of the two β-Lactam producers Acremonium chrysogenum and Penicillium chrysogenum : sporulation and hyphal morphology are controlled by subunits of the bud site selection system and the septation initiation network / Janina Kluge ; Gutachter: Ulrich Kück, Dominik Begerow ; Fakultät für Biologie und Biotechnologie." Bochum : Ruhr-Universität Bochum, 2019. http://d-nb.info/1177364263/34.

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10

Kluge, Janina [Verfasser], Ulrich Gutachter] Kück, and Dominik [Gutachter] [Begerow. "Multicellular development of the two β-Lactam producers Acremonium chrysogenum and Penicillium chrysogenum : sporulation and hyphal morphology are controlled by subunits of the bud site selection system and the septation initiation network / Janina Kluge ; Gutachter: Ulrich Kück, Dominik Begerow ; Fakultät für Biologie und Biotechnologie." Bochum : Ruhr-Universität Bochum, 2019. http://d-nb.info/1177364263/34.

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Books on the topic "Acremonium chrysogenum"

1

Hauck, Katarzyna. Transposonen und Regulation der Genexpression bei den Antibiotika-produzierenden Pilzen Penicillium chrysogenum und Acremonium chrysogenum. Berlin: J. Cramer, 2002.

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2

Glukoseregulation der Cephalosporin C-biosynthese im Hyphenpilz Acremonium chrysogenum. Berlin: J. Cramer, 1999.

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3

Radzio, Renate. Heterologe Genexpression in dem Cephalosporin C produzierenden Hyphenpilz Acremonium chrysogenum. Berlin: J. Cramer, 1997.

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4

Molekulare Analysen zur Expression von gbs-Lactam-Genen bei Acremonium chrysogenum. Berlin: J. Cramer, 1992.

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5

Pfeil, Michael. Funktionsanalyse und molekulare Charakterisierung der bifunktionalen Expandase/Hydroxylase aus dem Hyphenpilz Acremonium chrysogenum. Berlin: J. Cramer, 2001.

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6

Nosek, Jörg. Regulation spezifischer Gene in der Cephalosporin C Biosynthese von Acremonium chrysogenum. Berlin: J. Cramer, 1997.

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Der Transkriptionsfaktor CPCR1, ein Regulator der Cephalosporin C-Biosynthesegene in Acremonoim chrysogenum. Berlin: J. Cramer, 1999.

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8

Heterologe Gene Expression in Dem Cephalosporin C Produzierenden Hyphenpilz Acremonium Chrysogenum (Bibliotheca Mycologica). Gebruder Borntraeger Verlagsbuchhandlung, 1997.

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Regulation Spezifischer Gene in Der Cephalosporin C Biosynthese Von Acremonium Chrysogenum (Bibliotheca Mycologica,). Gebruder Borntraeger Verlagsbuchhandlung, 1997.

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Book chapters on the topic "Acremonium chrysogenum"

1

Bellgardt, Karl-Heinz. "β-Lactam Antibiotics Production with Penicillium chrysogenum and Acremonium chrysogenum." In Bioreaction Engineering, 391–432. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-59735-0_14.

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2

García-Estrada, Carlos, and Ricardo V. Ullán. "RNAi-Mediated Gene Silencing in the Beta-Lactam Producer Fungi Penicillium chrysogenum and Acremonium chrysogenum." In Fungal Biology, 125–30. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-10503-1_9.

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Tollnick, C., G. Seidel, M. Beyer, and K. Schügerl. "Investigations of the Production of Cephalosporin C by Acremonium chrysogenum." In New Trends and Developments in Biochemical Engineering, 1–45. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/b12439.

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Seidel, G., C. Tollnick, M. Beyer, and K. Schügerl. "On-line and Off-line Monitoring of the Production of Cephalosporin C by Acremonium chrysogenum." In Bioanalysis and Biosensors for Bioprocess Monitoring, 115–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/3-540-48773-5_4.

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RodrÍguez-Sáiz, Marta, Juan-Luis Fuente, and José-Luis Barredo. "Metabolic Engineering of Acremonium chrysogenum to Produce Deacetoxycephalosporin C and Bioconversion to 7-Aminodeacetoxycephalosporanic Acid." In Microbial Processes and Products, 41–64. Totowa, NJ: Humana Press, 2005. http://dx.doi.org/10.1385/1-59259-847-1:041.

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6

Hu, Youjia. "Genetic Engineering of Acremonium chrysogenum, the Cephalosporin C Producer." In Genetic Engineering. InTech, 2013. http://dx.doi.org/10.5772/55471.

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