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Relevant bibliographies by topics / ACRIDINE SERIES

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Academic literature on the topic 'ACRIDINE SERIES'

Author: Grafiati

Published: 5 June 2025

Last updated: 1 August 2025

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Journal articles on the topic "ACRIDINE SERIES"

1

Krochtová, Kristína, Annamária Halečková, Ladislav Janovec, Michaela Blizniaková, Katarína Kušnírová, and Mária Kožurková. "Novel 3,9-Disubstituted Acridines with Strong Inhibition Activity against Topoisomerase I: Synthesis, Biological Evaluation and Molecular Docking Study." Molecules 28, no. 3 (2023): 1308. http://dx.doi.org/10.3390/molecules28031308.

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A series of novel 3,9-disubstituted acridines were synthesized and their biological potential was investigated. The synthetic plan consists of eight reaction steps, which produce the final products, derivatives 17a–17j, in a moderate yield. The principles of cheminformatics and computational chemistry were applied in order to study the relationship between the physicochemical properties of the 3,9-disubstituted acridines and their biological activity at a cellular and molecular level. The selected 3,9-disubstituted acridine derivatives were studied in the presence of DNA using spectroscopic (U

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2

Godard, A., P. Rocca, F. Guillier та ін. "Ortho-directed metallation of π-deficient heterocycles in connection with palladium-catalyzed biaryl cross-coupling Synthesis of marine alkaloids of the pyridoacridine series". Canadian Journal of Chemistry 79, № 11 (2001): 1754–61. http://dx.doi.org/10.1139/v01-147.

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Connection between ortho-directed metallation of π-deficient heterocycles and Suzuki cross-coupling reactions provides a very efficient and fruitful strategy to polycyclic molecules of biological interest. The methodology is used to synthesize alkaloids or precursors and analogues of natural compounds of the pyrido[2,3,4-k,l]acridine series.Key words: marine alkaloids, pyrido[2,3,4-k,l]acridines, metallation, cross-coupling.

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3

Di Giorgio, Carole, Florence Delmas, Nathalie Filloux, et al. "In Vitro Activities of 7-Substituted 9-Chloro and 9-Amino-2-Methoxyacridines and Their Bis- and Tetra-Acridine Complexes against Leishmania infantum." Antimicrobial Agents and Chemotherapy 47, no. 1 (2003): 174–80. http://dx.doi.org/10.1128/aac.47.1.174-180.2003.

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ABSTRACT 9-Chloro and 9-amino-2-methoxyacridines bearing different substituents in position 7, as well as their corresponding unsubstituted dimeric and tetrameric complexes, were investigated for in vitro antiproliferative properties against Leishmania infantum compared to toxicity towards human monocytes. The results clearly confirmed that several compounds of the 2-methoxyacridine series, together with their corresponding dimeric and tetrameric derivatives, had strong in vitro antiparasitic properties. Antileishmanial activity was shown to depend on the nature of both 7- and 9-substituted gr

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4

Pravin, R. Kawle, and P. Deohate Pradip. "Synthesis of heterocycles containing pyrimidine-acridine rings by microwave irradiation, antimicrobial study and its comparison with classical heating." Journal of Indian Chemical Society Vol. 92, Jun 2015 (2015): 925–28. https://doi.org/10.5281/zenodo.5637765.

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Department of Chemistry, Shri R. L. T. College of Science, Akola-444 001, Maharashtra, India <em>E-mail</em> : pravink280685@rediffmail.com New series of linked heterocycles containing acridine and pyrimidines were prepared in high yield from condensation of <em>N</em>-acridin-9-yl-3-oxo-butyramide with urea or thiourea or guanidine by microwave irradiation and by conventional heating for comparative study purpose. The representative compounds characterized on the basis of IR, <sup>1</sup>H NMR and Mass spectral beside elemental analysis. Microwave assisted synthesized compounds evaluated for

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5

Sharhan, Olla, Thorsten Heidelberg, Najiahah Mohd Hashim, Abbas Abdulameer Salman, Hapipah Mohd Ali, and Soher Nagi Jayash. "Synthesis and biological study of acridine-based imidazolium salts." RSC Advances 8, no. 68 (2018): 38995–9004. http://dx.doi.org/10.1039/c8ra08138g.

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6

Roe, S., M. Gunaratnam, C. Spiteri, et al. "Synthesis and biological evaluation of hybrid acridine-HSP90 ligand conjugates as telomerase inhibitors." Organic & Biomolecular Chemistry 13, no. 31 (2015): 8500–8504. http://dx.doi.org/10.1039/c5ob01177a.

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7

Rosero-Mafla, Miguel A., Jhon Zapata-Rivera, M. Concepción Gimeno, and Renso Visbal. "Steric and Electronic Effects in N-Heterocyclic Carbene Gold(III) Complexes: An Experimental and Computational Study." Molecules 27, no. 23 (2022): 8289. http://dx.doi.org/10.3390/molecules27238289.

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A series of neutral acridine-based gold(III)-NHC complexes containing the pentafluorophenyl (–C6F5) group were synthesized. All of the complexes were fully characterized by analytical techniques. The square planar geometry around the gold center was confirmed by X-ray diffraction analysis for complexes 1 (Trichloro [1-methyl-3-(9-acridine)imidazol-2-ylidene]gold(III)) and 2 (Chloro-bis(pentafluorophenyl)[1-methyl-3-(9-acridine)imidazol-2-ylidene]gold(III)). In both cases, the acridine rings play a key role in the crystal packing of the solid structures by mean of π–π stacking interactions, wit

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8

Potdar, Shweta, Nikita Pal, Pratibha Sharma, and Ashok Kumar. "The catalytic influence of phosphotungstic acid-functionalized Fe3O4 MNPs blended with TiO2 on the synthesis of novel spiro-acridines and the evaluation of their medicinal potential through molecular docking studies." RSC Advances 10, no. 72 (2020): 44442–52. http://dx.doi.org/10.1039/d0ra06975b.

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This manuscript describes an effective and rapid three-component synthesis of a novel series of spiro-acridine derivatives by integrating the pharmacologically dynamic hydantoin–phenytoin as the prime synthetic equivalent.

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9

Druzina, Anna A., Nadezhda V. Dudarova, Ivan V. Ananyev, et al. "New Boron Containing Acridines: Synthesis and Preliminary Biological Study." Molecules 28, no. 18 (2023): 6636. http://dx.doi.org/10.3390/molecules28186636.

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The synthesis of the first conjugates of acridine with cobalt bis(dicarbollide) are reported. A novel 9-azido derivative of acridine was prepared through the reaction of 9-methoxyacridine with N3CH2CH2NH2, and its solid-state molecular structure was determined via single-crystal X-ray diffraction. The azidoacridine was used in a copper (I)-catalyzed azide-alkyne cycloaddition reaction with cobalt bis(dicarbollide)-based terminal alkynes to give the target 1,2,3-triazoles. DNA interaction studies via absorbance spectroscopy showed the weak binding of the obtained conjugates with DNA. The antipr

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10

Piestrzeniewicz, Mariola K., Dorota Wilmańska, Kazimierz Studzian, et al. "Inhibition of RNA Synthesis in vitro by Acridines - Relation between Structure and Activity." Zeitschrift für Naturforschung C 53, no. 5-6 (1998): 359–68. http://dx.doi.org/10.1515/znc-1998-5-610.

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Abstract The effects of acridine derivatives (proflavine and 2,7-dialkyl derivatives, diacridines and triacridines, 9-aminoacridine carboxamides, and 9-anilinoacridine, amsacrine and its congeners) on overall RNA synthesis in vitro, on synthesis of initiating oligonucleotides and the binding of the enzyme to DNA were studied. The primary mechanism of action is related to inhibition of the enzyme binding to DNA. The acridines (intercalating or non-intercalating and bis-intercalating ligands) assayed here differ in the properties of their complexes with DNA. Correlation is generally observed bet

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Book chapters on the topic "ACRIDINE SERIES"

1

Henry, David W. "Acridine Antimalarials." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch19.

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2

Tilak, B. D., and N. R. Ayyangar. "Acridine Dyes." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch9.

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3

Saxton, J. E. "The Acridine Alkaloids." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch5.

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4

Raulins, N. R. "Acridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch2.

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5

Nicholson, B. H. "Acridines and Enzymes." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch16.

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6

Mccapra, Frank. "Chemiluminescent Reactions of Acridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch10.

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7

Robinson, D. A. "Benzacridines and Condensed Acridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch8.

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8

Acheson, R. M. "The Infrared Spectra of Acridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch12.

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9

Bolton, R. G. "The Mass Spectra of Acridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch14.

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10

Dean, A. C. R. "The Antibacterial Action of Acridines." In Chemistry of Heterocyclic Compounds: A Series Of Monographs. John Wiley & Sons, Inc., 2008. http://dx.doi.org/10.1002/9780470186596.ch17.

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