Relevant bibliographies by topics / Act on the Safety of Regenerative Medicine

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  2. Dissertations / Theses
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Academic literature on the topic 'Act on the Safety of Regenerative Medicine'

Author: Grafiati
Published: 3 June 2025
Last updated: 31 July 2025

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Journal articles on the topic "Act on the Safety of Regenerative Medicine"

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Tobita, Morikuni, Kenji Konomi, Yasuhiro Torashima, Kenichi Kimura, Masaomi Taoka, and Masahiro Kaminota. "Japan's challenges of translational regenerative medicine: Act on the safety of regenerative medicine." Regenerative Therapy 4 (June 2016): 78–81. http://dx.doi.org/10.1016/j.reth.2016.04.001.

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Hosoya, Satoshi, Sena Awano-Kim, Ryo Yokomizo, et al. "Regenerative medicine in Obstetrics & Gynecology: Current status under the Act on the Safety of Regenerative Medicine in Japan." Regenerative Therapy 26 (June 2024): 564–70. http://dx.doi.org/10.1016/j.reth.2024.08.003.

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Raut, Sayali, Anuja Ikhar, and Jay Bhopatkar. "Glass that Heals: Exploring the Wonders of Bioactive Glass." Journal of Datta Meghe Institute of Medical Sciences University 18, no. 4 (2023): 860–63. http://dx.doi.org/10.4103/jdmimsu.jdmimsu_189_23.

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Abstract In today’s world, dental and bone defect incidences have become very common, and regenerative treatment has shown very effective results. As such, it might affect the whole quality of life of an individual. Moreover, the present studies show that now, it is possible to heal or treat certain dental diseases by use of some regenerative material and bioactive glass (BAG) is one of them and also is proved to be helpful in various dermatological conditions. Its safety and effectiveness are more as compared to other biomaterials. This review focuses on one of the versatile materials which a
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Lebiedzińska, Julia. "Polydeoxyribonucleotides – the future of regenerative medicine." Aesthetic Cosmetology and Medicine 14, no. 3 (2025): 115–20. https://doi.org/10.52336/acm.2025.017.

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Polydeoxyribonucleotides (PDRN) are fragments of deoxyribonucleic acid (DNA) obtained from fish sperm. They have the ability to stimulate angiogenesis, i.e., the formation of new blood vessels. The article aimed to present the current state of knowledge of the potential use of PDRN in regenerative and aesthetic medicine. Their mechanisms of action were discussed, including their ability to stimulate angiogenesis, collagen synthesis, and anti-inflammatory effects. The results of the latest scientific research indicate the effectiveness of PDRN in anti-aging treatments, scars, stretch marks, and
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Khushi, Patel* Hitesh Raval. "An Overview on Japan's Regenerative Medicine Policies: Cellular and Tissue-Based Products Examined." International Journal of Pharmaceutical Sciences 3, no. 2 (2025): 1290–311. https://doi.org/10.5281/zenodo.14878652.

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Human cells and tissue products belong to a relatively new class of medical products. The products were classified as human cells, tissue, and cellular and tissue-based products (HCT/Ps) in the US, advanced therapy medicinal products (ATMPs) in the EU, and cell/tissue-engineered products in Japan. The Ministry of Health, Labour and Welfare (MHLW) and the Pharmaceuticals and Medical Devices Agency (PMDA) are the key regulatory authorities overseeing these products. The Pharmaceutical and Medical Device Act, Japan 2013 Chapter 9: Section 6 Handling of Cellular and Tissue-based Products (Articles
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Sameshima, Tadashi. "The Change of Research and Development Environment by Act on the Safety of Regenerative Medicine and Revised Pharmaceutical Affairs Act:." Iryo To Shakai 28, no. 1 (2018): 103–13. http://dx.doi.org/10.4091/iken.29.033.

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Thomas, Nebu George, Lekshmi M, Thomas George.V, and Kavya S. "Biological modifiers in bone graft for periodontal regeneration." IP International Journal of Periodontology and Implantology 8, no. 2 (2023): 86–93. http://dx.doi.org/10.18231/j.ijpi.2023.018.

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Periodontal diseases such as gingivitis and periodontitis leads to degradation of periodontal tissues, causing tooth movement, and eventually tooth loss. Regenerative periodontal therapies aim to promote the healing and regeneration of the damaged periodontal tissues. These therapies focus on restoring the lost periodontal structures, including the gum tissue, periodontal ligament, and bone, to a functional state. To promote periodontal regeneration and healing, the application of biologic modifiers such as growth factors has been investigated. Biologic modifiers-primarily growth factors are b
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Tobita, Morikuni. "Current state and issues related to cell therapy under the Act on the Safety of Regenerative Medicine." Personalized Medicine Universe 7 (July 2018): 37–38. http://dx.doi.org/10.1016/j.pmu.2018.04.003.

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Uno, Y., K. Nakamura, M. Tobita, et al. "Compilation and Issue of Basic Points to Consider for Cell Storage under the Act on the Safety of Regenerative Medicine by the Japanese Society for Regenerative Medicine." Cytotherapy 27, no. 5 (2025): S130—S131. https://doi.org/10.1016/j.jcyt.2025.03.257.

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Wang, Lei, Yefan Duan, Shujie Lu, and Jianfei Sun. "Magnetic Nanomaterials Mediate Electromagnetic Stimulations of Nerves for Applications in Stem Cell and Cancer Treatments." Journal of Functional Biomaterials 14, no. 2 (2023): 58. http://dx.doi.org/10.3390/jfb14020058.

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Although some progress has been made in the treatment of cancer, challenges remain. In recent years, advancements in nanotechnology and stem cell therapy have provided new approaches for use in regenerative medicine and cancer treatment. Among them, magnetic nanomaterials have attracted widespread attention in the field of regenerative medicine and cancer; this is because they have high levels of safety and low levels of invasibility, promote stem cell differentiation, and affect biological nerve signals. In contrast to pure magnetic stimulation, magnetic nanomaterials can act as amplifiers of
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Dissertations / Theses on the topic "Act on the Safety of Regenerative Medicine"

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Scarfe, L. N. "Investigating the safety and efficacy of regenerative medicine therapies in mouse models of kidney disease." Thesis, University of Liverpool, 2017. http://livrepository.liverpool.ac.uk/3008791/.

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Acute kidney injury (AKI) and chronic kidney disease (CKD) are serious health problems with high morbidity and mortality. There are currently no specific treatments available to patients with AKI or CKD, and many patients require renal replacement therapy to survive. Cell-based regenerative medicine therapies have shown potential for treating AKI and CKD in preclinical models, however conventional methods of measuring kidney function and tracking exogenously administered cells are not ideal. Novel imaging-based methods provide an alternative approach, allowing kidney function and cell biodistr
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Laurens, Johannes Bernardus. "A comparative analysis of the regulatory framework of the therapeutic application of stem cell technologies." Diss., University of Pretoria, 2017. http://hdl.handle.net/2263/62543.

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Stem cell technologies as a branch of regenerative medicine are becoming increasingly popular as the science behind it evolves. Therefore, it is important that the regulatory framework pertaining to stem cell technologies be well defined and appropriate to prevent unethical and unscrupulous behaviour on the part of medical practitioners, which gives rise to stem cell tourism. South African legislation pertaining to stem cell technology is regarded as inadequate and dissonant with the Constitution, exacerbating the problem of stem cell tourism and denying patients access to certain stem cell th
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Sillars, Dawn. "Balancing Act: Female Surgeons Adaptations to the Operating Environment." The Ohio State University, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=osu1546611638366225.

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Schwarz, Christopher Charles. "Attack-ademically Ineligible: Student Athlete Sex Crimes and the Dangerous Misunderstandings of FERPA." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1457096185.

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Books on the topic "Act on the Safety of Regenerative Medicine"

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Labour, Ontario Ministry of. Appealing orders issued under the Occupational Health and Safety Act: Policy and procedures. Ontario Ministry of Labour, 1987.

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Kapoor, Mohit, and Nizar N. Mahomed. Osteoarthritis: Pathogenesis, Diagnosis, Available Treatments, Drug Safety, Regenerative and Precision Medicine. Adis, 2016.

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Kapoor, Mohit, and Nizar N. Mahomed. Osteoarthritis: Pathogenesis, Diagnosis, Available Treatments, Drug Safety, Regenerative and Precision Medicine. Adis International, Limited, 2015.

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Kapoor, Mohit, and Nizar N. Mahomed. Osteoarthritis: Pathogenesis, Diagnosis, Available Treatments, Drug Safety, Regenerative and Precision Medicine. Adis, 2015.

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Staender, Sven, and Andrew Smith. Safety and quality assurance in anaesthesia. Edited by Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0036.

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Quality assurance has its roots in industry and therefore is strongly influenced by concepts from business, hence the reference to the definition of the term ‘quality’ according to the International Standard Organization (ISO), for example. In order to better understand the various concepts of quality assurance, this chapter clarifies concepts such as ‘effectiveness’, ‘efficiency’, ‘patient-centredness’, and ‘equity’. Of major importance in clinical medicine are guidelines, standards, recommendations, and their grade of evidence. Guidelines in particular have the advantage of facilitation of t
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Book chapters on the topic "Act on the Safety of Regenerative Medicine"

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Candido, Kenneth D., and Tennison Malcolm. "Fluoroscopic Safety." In Regenerative Medicine. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-75517-1_14.

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Van Pham, Phuc, Khanh Hong Thien Bui, Dat Quoc Ngo, et al. "Expanded Adipose Tissue-Derived Stem Cells for Articular Cartilage Injury Treatment: A Safety and Efficacy Evaluation." In Regenerative Medicine. Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-6542-2_11.

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Sinha, Garima, Sarah A. Bliss, Lauren S. Sherman, Oleta A. Sandiford, Vipul Nagula, and Pranela Rameshwar. "Mesenchymal Stem Cells and Pathotropism: Regenerative Potential and Safety Concerns." In The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis. River Publishers, 2022. http://dx.doi.org/10.1201/9781003339779-2.

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Vatsa, Pankhi, Sadaf Jahan, Uzair Ahmad Ansari, et al. "Stem Cell Safety and Sterility Testing: A Promising Approach in Regenerative Medicine." In Stem Cell Production. Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-7589-8_9.

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Nundy, Samiran, Atul Kakar, and Zulfiqar A. Bhutta. "Ethics in Research." In How to Practice Academic Medicine and Publish from Developing Countries? Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-5248-6_13.

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AbstractEthics is a set of moral principles of ‘what is right?’ and ‘what is wrong?’ or, in simple words, ‘what is good and what is bad?’ When the same principles are applied to medicine, the subject is called medical ethics. It is expected that a doctor should act in a particular way and follow certain rules. Medical ethics are professional standards for physicians. Bioethics is a branch of medical ethics and deals with complex issues like euthanasia, transplant medicine, genetic medicine, assisted reproduction therapy, human cloning, and medical genomics. Medical ethics and bioethics concept
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Lomas, Richard, Neil D. Avent, and Vehid Salih. "Tissue Banking." In Transfusion and Transplantation Science. Oxford University Press, 2018. http://dx.doi.org/10.1093/hesc/9780198735731.003.0011.

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This chapter illustrates how tissue grafts are used clinically, and examines the process by which tissue grafts are collected and treated to improve their clinical efficacy, make them safer, and render them suitable for long-term storage. It also shows how donors are selected and screened, and how consent is obtained. The chapter then outlines how tissues are procured from living and deceased donors, how the collected tissue is processed, how that tissue is preserved, and how tissues are stored and distributed. Near the end, the chapter talks about the requirements of the UK Human Tissue Act.
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A Becker-Kojić, Zorica, José Manuel García-Verdugo, Anne-Kathrin Schott, Vicente Herranz-Pérez, Ivan Zipančić, and Vicente Hernández-Rabaza. "Membrane-to-Nucleus Signaling in Human Blood Progenitor Cells Reveals an Efficient GM-Free Reprogramming to Pluripotency." In Stem Cell Research [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.108950.

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The generation of induced pluripotent stem cells (iPSCs) by forced expression of defined transcription factors has revolutionized regenerative medicine. These cells have similar features to embryonic stem cells (ESCs) regarding self-renewal and their ability to differentiate into any cell type in the body. In spite of many improvements, in using nonviral delivery reprogramming methods, there are still challenges to overcome regarding safety before patient-made iPSCs can be used in regular clinical practice. We have recently reported about a gene manipulation-free method of generating human plu
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Chang, You-Kang, and Oscar Lee. "Safety issue of nanoparticles which used for stem cell labeling and tracking." In Nanomaterials and regenerative medicine. IAPC Publishing, 2016. http://dx.doi.org/10.5599/obp.9.13.

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Chen, Chao, Hongli Zhu, and Kunping Yan. "Glutaraldehyde Polymerized Porcine Hemoglobin: Preparation, Safety Evaluation and Pharmacodynamics Study." In Regenerative Medicine, Artificial Cells and Nanomedicine. WORLD SCIENTIFIC, 2013. http://dx.doi.org/10.1142/9789814472869_0003.

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Dostert, G., V. Jouan-Hureaux, H. Louis, and É. Velot. "Umbilical Mesenchymal Stem Cell-Derived Extracellular Vesicle Conditioning Has an Immunosuppressive Effect on NK Cells." In Stem Cells and Regenerative Medicine. IOS Press, 2021. http://dx.doi.org/10.3233/bhr210028.

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Background: In peripheral blood, human natural killer (NK) cells are immunological cells that nearly don’t express the ectonucleotidase CD73 on their plasma membrane. When exposed to mesenchymal stem cells (MSCs), NK cells are able to acquire CD73. MSCs are known to be CD73-positive (CD73+) and also to modulate the immune system, e.g. through adenosynergic pathway by ectonucleosidases, such as CD73. Extracellular vesicles (EVs) are involved in cell-to-cell communication. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have emerged as paracrine mediators that are part of MSC immu
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Conference papers on the topic "Act on the Safety of Regenerative Medicine"

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Alegre-Aguarón, Elena, Sonal R. Sampat, Perry J. Hampilos, et al. "Biomarker Identification Under Growth Factor Priming for Cartilage Tissue Engineering." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80374.

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Adult articular cartilage has a poor healing capacity, which has lead to intense research toward development of cell-based therapies for cartilage repair. The destruction of articular cartilage results in osteoarthritis (OA), which affects about 27 million Americans. In order to create functional tissue, it is essential to mimic the native environment by optimizing expansion protocols. Cell passaging and priming with chemical or physical factors are often necessary steps in cell-based strategies for regenerative medicine [1]. The ability to identify biomarkers that can act as predictors of cel
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Grigorie (Patru), Larisa, and Ciprian-Laurentiu Patru. "GOING DIGITAL: THE TRANSFORMATION OF THE HEALTHCARE SECTOR BY ARTIFICIAL INTELLIGENCE." In 9th SWS International Scientific Conferences on SOCIAL SCIENCES - ISCSS 2022. SGEM WORLD SCIENCE, 2022. http://dx.doi.org/10.35603/sws.iscss.2022/s13.109.

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The aim of this research is to analyze how digitization impacts the healthcare services. The alert pace of innovation changes the face of traditional medicine and brings change for all those involved in the medical act: doctors, patients, management, authorities. For them, it is vital to know the many forms that digitization can take in the provision of healthcare services. The development of personalized medicine and the empowerment of patients are global goals that involve digital e-health services. The synergy between digitization-innovation-research has become a sine-qua-non condition for
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Shah, Vrushank, Usmaan Al-Shehab, Keyur Patel, and Alexander King. "Mesenchymal Stem Cell Therapy for Amyotrophic Lateral Sclerosis." In 27th Annual Rowan-Virtua Research Day. Rowan University Libraries, 2023. https://doi.org/10.31986/issn.2689-0690_rdw.stratford_research_day.148_2023.

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Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig disease, is a fatal neurodegenerative disease affecting motor neurons in the brain and spinal cord. Progressive muscle weakness, atrophy, and spasticity characterize the condition, which eventually leads to paralysis and respiratory failure. There is currently no cure for ALS, and the standard of care is supportive, with riluzole being the only approved medication that has been shown to slightly slow disease progression (1). However, the use of mesenchymal stem cells (MSCs) in the treatment of ALS is a new area of research in regene
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Ly, Chenda, Sirintip Chaichalotornkul, Tawee Saiwichai, Thamthiwat Nararatwanchai, and Chantawat Kasemne. "The Anatomy Study of the Facial Temporal Region, Age 25-50, in Thai Population Based on Ultrasound Investigation." In The International Halal Science and Technology Conference 2024 (IHSATEC): 17th Halal Science Industry and Business (HASIB). Yayasan Sinergi Riset dan Edukasi, 2025. https://doi.org/10.31098/hst24144.

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THE ANATOMY STUDY OF THE FACIAL TEMPORAL REGION, AGE 25-50, IN THAI POPULATION BASED ON ULTRASOUND INVESTIGATION | Chenda Ly, Sirintip Chaichalotornkul, Tawee Saiwichai, Thamthiwat Nararatwanchai, Chantawat Kasemnet SkinMedics Clinic, School of Anti-aging and Regenerative Medicine, Faculty of Public Health, School of Anti-aging and Regenerative Medicine, Dr. Art Aesthetic Clinic Abstract Background – Aging, influenced by genetics and environment, affects facial tissues, including skin, fat, muscles, and bones. The temporal region is significant for both function and appearance. Many Thais are
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Dougherty, John, Emily Schaefer, Ryan Niemeier, Erin Koch, Craig Cady, and Kalyani Nair. "Effect of Valproic Acid on Cell Proliferation of Wharton’s Jelly MSC in PCL Nanofiber Scaffolds." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-65041.

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The field of tissue engineering and regenerative medicine is an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole organ. The process involves seeding cells onto biocompatible scaffolds that temporarily act as a supporting structure for cells to attach and grow. Scaffolds for tissue regeneration must present a viable microenvironment for the living cells to adhere, proliferate, and exhibit the necessary tissue function. Electrospinning is an emerging
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Ebnali, Mahdi, Andrew Goldsmith, Barbara Burian, et al. "AR-Coach: Using Augmented Reality (AR) for Real-Time Clinical Guidance During Medical Emergencies on Deep Space Exploration Missions." In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1002100.

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Space travel imposes significant risks to crew health due to physiological adaptations, exposure to physical and psychological stressors, and limited capabilities to provide medical care. When medical emergencies occur, appropriate use of diagnostic and procedural guidance tools are crucial countermeasures against the risks of injury and mission failure. Point-of-care ultrasound (POCUS) is the only portable imaging modality available during exploration missions that can provide critical and dynamic medical information. Developing competency in POCUS is time-consuming and it is usually achieved
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