Relevant bibliographies by topics / Actinomycetales, infection

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Academic literature on the topic 'Actinomycetales, infection'

Author: Grafiati
Published: 4 June 2021
Last updated: 11 February 2022

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Journal articles on the topic "Actinomycetales, infection"

1

HOLTZ, HOWARD A. "Actinomycetales Infection in the Acquired Immunodeficiency Syndrome." Annals of Internal Medicine 102, no. 2 (February 1, 1985): 203. http://dx.doi.org/10.7326/0003-4819-102-2-203.

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2

Ablanedo-Terrazas, Yuria, Christopher E. Ormsby, and Gustavo Reyes-Terán. "Palatal Actinomycosis and Kaposi Sarcoma in an HIV-Infected Subject with DisseminatedMycobacterium avium-intracellulareInfection." Case Reports in Medicine 2012 (2012): 1–3. http://dx.doi.org/10.1155/2012/679728.

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ActinomycesandMycobacterium avium-intracellulareare facultative intracellular organisms, members of the bacterial order actinomycetales. AlthoughActinomycescan behave as copathogen when anatomic barriers are compromised, its coinfection withMycobacterium avium-intracellularehas not previously been reported. We present the first reported case of palatal actinomycosis co-infection with disseminated MAC, in an HIV-infected subject with Kaposi sarcoma and diabetes. We discuss the pathogenesis of the complex condition of this subject.
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3

Berry, A. M., L. McIntyre, and M. E. McCully. "Fine structure of root hair infection leading to nodulation in the Frankia–Alnus symbiosis." Canadian Journal of Botany 64, no. 2 (February 1, 1986): 292–305. http://dx.doi.org/10.1139/b86-043.

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Root hair infection by Frankia (Actinomycetales) is the means by which nitrogen-fixing root nodules are initiated upon the actinorhizal host, Alnus rubra. Structural details of the infectious process and the changes in host root hair cells are demonstrated at the prenodule stage for the first time using light and transmission electron microscopy. The Frankia hypha is the infective agent, extending from the rhizosphere through the root hair wall in a highly deformed region of the hair. There is no evidence of pleomorphism of the Frankia hypha. The primary wall fibrils of the root hair appear disorganized at the site of penetration. There is extensive secondary wall formation in the infected hair. At the site of penetration, root hair cell wall ingrowths occur that are structurally consistent with transfer cell wall formation. The ingrowths are continuous with the encapsulating wall layer surrounding the Frankia hypha The host cytoplasm is rich in ribosomes, secretory products, and organelles, including Golgi bodies, mitochondria, plastids, and profiles of endoplasmic reticulum. In an aborted infection sequence, some structural features of the host response to Frankia are observable, while other aspects of successful infection do not occur. Limited transfer cell wall is formed at the site of near infection. The root hair cytoplasm is senescent, however, and a callosic plug appears to surround the pathway of infection.
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4

Fontanella, G. H., M. F. Pascutti, L. Daurelio, A. R. Perez, A. L. Nocito, D. Wojdyla, O. Bottasso, S. S. Revelli, and J. L. Stanford. "Improved outcome of Trypanosoma cruzi infection in rats following treatment in early life with suspensions of heat-killed environmental Actinomycetales." Vaccine 25, no. 17 (April 2007): 3492–500. http://dx.doi.org/10.1016/j.vaccine.2006.11.062.

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5

MacDonald, Ashlee, Irvin Oh, Alex Grier, Benjamin Smith, John Daiss, and Steven Gill. "Microbiome Analysis for Assessments of Treatment Response and Salvage Prognosis in Infected Diabetic Foot Ulcers." Foot & Ankle Orthopaedics 2, no. 3 (September 1, 2017): 2473011417S0000. http://dx.doi.org/10.1177/2473011417s000060.

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Category: Basic Sciences/Biologics, Diabetes Introduction/Purpose: Diabetic foot ulcers (DFUs) contribute to 80% of non-traumatic lower-extremity amputations. Surgeons are often forced to make surgical decision without adequate prognostic information. DFU infections are often polymicrobial, representing complex microbial communities. A microbiota is the ecological community of various microorganisms that share body space. Currently, the methods of detecting an active infection, identifying the pathogenic bacteria within the microbiome, measuring the response to therapy, and assessing prognosis are limited. Using a molecular genomic technique of 16 S rRNA sequencing, our goals are to assess the pathogenic bioburden of DFUs and to monitor the bacterial community changes in response to antibiotic treatment. Our hypothesis is that the microbiome in DFUs responding to debridement and antibiotics treatment is distinct from those that fail to respond. Methods: Patients with type I or II diabetes who presented with an infected DFU were enrolled. Infections were identified using clinical signs. The DFU size was measured and classified using the Wagner classification. Enrolled patients were initially managed with foot salvaging therapy (FST): irrigation and debridement followed by wet-to-dry dressings and 6 weeks of intravenous antibiotic treatment. Superficial and deep DFU samples were obtained and evaluated by 16 S rRNA microbiome analysis and qPCR for bacterial abundance. This was repeated at 4, 8, and 12 weeks following the initiation of FST. At 12 weeks, patients were divided into two groups, healed and non-healed, based on the change in the size of the wound and absence or presence of 12 secondary signs of infection. Alpha- and beta-diversity were measured by the Shannon index and Bray-Curtis dissimilarity index to evaluate changes in the microbiome between the healed and non-healed groups. Results: From July 2015 to August 2016, 21 patients were enrolled and 3 deceased due to medical comorbidities. Of the 18 patients available for follow-up, 10 failed FST and 8 healed. The qPCR and microbiome analysis revealed that the bacterial abundance and diversity of the bacterial community were substantially reduced following debridement and intravenous antibiotic treatment. At the initial enrollment, those group that healed versus non-healed showed significant differences in microbiome composition, with the healed group enriched with Actinomycetales and Staphylococcus, and the non-healed group enriched with Bacteroidales and Streptococcus. At week 4, such differences disappeared and bacterial abundance significantly decreased. New differences were evident at week 8: the healed group was enriched with Actinomycetales and non-healed group with Bacilli. Conclusion: Abundant presence of Bacteroidales and Streptococcus at the initial presentation of infected DFU maybe a poor prognostic sign for healing with FST. Through molecular analysis of the wound microbiome, we can identify pathogens of prognostic value at the initial cultures and assess response to therapy with significant differences at 8 weeks after. Our study provides useful information for counseling patients of treatment prognosis and determining to pursuit further foot salvage versus amputation.
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6

Sajnaga, Ewa, Marcin Skowronek, Agnieszka Kalwasińska, Waldemar Kazimierczak, Karolina Ferenc, Magdalena Lis, and Adrian Wiater. "Nanopore-Sequencing Characterization of the Gut Microbiota of Melolontha melolontha Larvae: Contribution to Protection against Entomopathogenic Nematodes?" Pathogens 10, no. 4 (March 25, 2021): 396. http://dx.doi.org/10.3390/pathogens10040396.

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This study focused on the potential relationships between midgut microbiota of the common cockchafer Melolontha melolontha larvae and their resistance to entomopathogenic nematodes (EPN) infection. We investigated the bacterial community associated with control and unsusceptible EPN-exposed insects through nanopore sequencing of the 16S rRNA gene. Firmicutes, Proteobacteria, Actinobacteria, and Bacteroidetes were the most abundant bacterial phyla within the complex and variable midgut microbiota of the wild M. melolontha larvae. The core microbiota was found to include 82 genera, which accounted for 3.4% of the total number of identified genera. The EPN-resistant larvae differed significantly from the control ones in the abundance of many genera belonging to the Actinomycetales, Rhizobiales, and Clostridiales orders. Additionally, the analysis of the microbiome networks revealed different sets of keystone midgut bacterial genera between these two groups of insects, indicating differences in the mutual interactions between bacteria. Finally, we detected Xenorhabdus and Photorhabdus as gut residents and various bacterial species exhibiting antagonistic activity against these entomopathogens. This study paves the way to further research aimed at unravelling the role of the host gut microbiota on the output of EPN infection, which may contribute to enhancement of the efficiency of nematodes used in eco-friendly pest management.
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7

Petrov, Vyacheslav A., María A. Fernández-Peralbo, Rico Derks, Elena M. Knyazeva, Nikolay V. Merzlikin, Alexey E. Sazonov, Oleg A. Mayboroda, and Irina V. Saltykova. "Biliary Microbiota and Bile Acid Composition in Cholelithiasis." BioMed Research International 2020 (July 2, 2020): 1–8. http://dx.doi.org/10.1155/2020/1242364.

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Background. A functional interplay between BAs and microbial composition in gut is a well-documented phenomenon. In bile, this phenomenon is far less studied, and with this report, we describe the interactions between the BAs and microbiota in this complex biological matrix. Methodology. Thirty-seven gallstone disease patients of which twenty-one with Opisthorchis felineus infection were enrolled in the study. The bile samples were obtained during laparoscopic cholecystectomy for gallstone disease operative treatment. Common bile acid composition was measured by LC-MS/MS. Gallbladder microbiota were previously analyzed with 16S rRNA gene sequencing on Illumina MiSeq platform. The associations between bile acid composition and microbiota were analyzed. Results. Bile acid signature and Opisthorchis felineus infection status exert influence on beta-diversity of bile microbial community. Direct correlations were found between taurocholic acid, taurochenodeoxycholic acid concentrations, and alpha-diversity of bile microbiota. Taurocholic acid and taurochenodeoxycholic acid both show positive associations with the presence of Chitinophagaceae family, Microbacterium and Lutibacterium genera, and Prevotella intermedia. Also, direct associations were identified for taurocholic acid concentration and the presence of Actinomycetales and Bacteroidales orders, Lautropia genus, Jeotgalicoccus psychrophilus, and Haemophilus parainfluenzae as well as for taurochenodeoxycholic acid and Acetobacteraceae family and Sphingomonas genus. There were no differences in bile acid concentrations between O. felineus-infected and noninfected patients. Conclusions/Significance. Associations between diversity, taxonomic profile of bile microbiota, and bile acid levels were evidenced in patients with cholelithiasis. Increase of taurochenodeoxycholic acid and taurocholic acid concentration correlates with bile microbiota alpha-diversity and appearance of opportunistic pathogens.
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8

Magalhães, Joana, Nina Franko, Samanta Raboni, Giannamaria Annunziato, Päivi Tammela, Agostino Bruno, Stefano Bettati, et al. "Discovery of Substituted (2-Aminooxazol-4-yl)Isoxazole-3-carboxylic Acids as Inhibitors of Bacterial Serine Acetyltransferase in the Quest for Novel Potential Antibacterial Adjuvants." Pharmaceuticals 14, no. 2 (February 23, 2021): 174. http://dx.doi.org/10.3390/ph14020174.

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Many bacteria and actinomycetales use L-cysteine biosynthesis to increase their tolerance to antibacterial treatment and establish a long-lasting infection. In turn, this might lead to the onset of antimicrobial resistance that currently represents one of the most menacing threats to public health worldwide. The biosynthetic machinery required to synthesise L-cysteine is absent in mammals; therefore, its exploitation as a drug target is particularly promising. In this article, we report a series of inhibitors of Salmonella thyphimurium serine acetyltransferase (SAT), the enzyme that catalyzes the rate-limiting step of L-cysteine biosynthesis. The development of such inhibitors started with the virtual screening of an in-house library of compounds that led to the selection of seven structurally unrelated hit derivatives. A set of molecules structurally related to hit compound 5, coming either from the original library or from medicinal chemistry efforts, were tested to determine a preliminary structure–activity relationship and, especially, to improve the inhibitory potency of the derivatives, that was indeed ameliorated by several folds compared to hit compound 5 Despite these progresses, at this stage, the most promising compound failed to interfere with bacterial growth when tested on a Gram-negative model organism, anticipating the need for further research efforts.
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9

Lavire, Céline, Didier Blaha, and Benoit Cournoyer. "Selection of Unusual Actinomycetal Primary σ70 Factors by Plant-Colonizing Frankia Strains." Applied and Environmental Microbiology 70, no. 2 (February 2004): 991–98. http://dx.doi.org/10.1128/aem.70.2.991-998.2004.

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ABSTRACT Functional adaptations of σ70 transcriptional factors led to the emergence of several paralogous lineages, each one being specialized for gene transcription under particular growth conditions. Screening of a Frankia strain EaI-12 gene library by σ70 DNA probing allowed the detection and characterization of a novel actinomycetal primary (housekeeping) σ70 factor. Phylogenetic analysis positioned this factor in the RpoD cluster of proteobacterial and low-G+C-content gram-positive factors, a cluster previously free of any actinobacterial sequences. σ70 DNA probing of Frankia total DNA blots and PCR screening detected one or two rpoD-like DNA regions per species. rpoD matched the conserved region in all of the species tested. The other region was found to contain sigA, an alternative primary factor. sigA appeared to be strictly distributed among Frankia species infecting plants by the root hair infection process. Both genes were transcribed by Frankia strain ACN14a grown in liquid cultures. The molecular phylogeny of the σ70 family determined with Frankia sequences showed that the alternative actinomycetal factors and the essential ones belonged to the same radiation. At least seven distinct paralogous lineages were observed among this radiation, and gene transfers were detected in the HrdB actinomycetal lineage.
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10

Hugonnet, Jean-Emmanuel, Nabila Haddache, Carole Veckerlé, Lionel Dubost, Arul Marie, Noriyasu Shikura, Jean-Luc Mainardi, Louis B. Rice, and Michel Arthur. "Peptidoglycan Cross-Linking in Glycopeptide-Resistant Actinomycetales." Antimicrobial Agents and Chemotherapy 58, no. 3 (January 6, 2014): 1749–56. http://dx.doi.org/10.1128/aac.02329-13.

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ABSTRACTSynthesis of peptidoglycan precursors ending ind-lactate (d-Lac) is thought to be responsible for glycopeptide resistance in members of the orderActinomycetalesthat produce these drugs and in related soil bacteria. More recently, the peptidoglycan of several members of the orderActinomycetaleswas shown to be cross-linked byl,d-transpeptidases that use tetrapeptide acyl donors devoid of the target of glycopeptides. To evaluate the contribution of these resistance mechanisms, we have determined the peptidoglycan structure ofStreptomyces coelicolorA(3)2, which harbors avanHAXgene cluster for the production of precursors ending ind-Lac, andNonomuraeasp. strain ATCC 39727, which is devoid ofvanHAXand produces the glycopeptide A40296. Vancomycin retained residual activity againstS. coelicolorA(3)2 despite efficient incorporation ofd-Lac into cytoplasmic precursors. This was due to ad,d-transpeptidase-catalyzed reaction that generated a stem pentapeptide recognized by glycopeptides by the exchange ofd-Lac ford-Ala and Gly. The contribution ofl,d-transpeptidases to resistance was limited by the supply of tetrapeptide acyl donors, which are essential for the formation of peptidoglycan cross-links by these enzymes. In the absence of a cytoplasmic metallo-d,d-carboxypeptidase, the tetrapeptide substrate was generated by hydrolysis of the C-terminald-Lac residue of the stem pentadepsipeptide in the periplasm in competition with the exchange reaction catalyzed byd,d-transpeptidases. InNonomuraeasp. strain ATCC 39727, the contribution ofl,d-transpeptidases to glycopeptide resistance was limited by the incomplete conversion of pentapeptides into tetrapeptides despite the production of a cytoplasmic metallo-d,d-carboxypeptidase. Since the level of drug production exceeds the level of resistance, we propose thatl,d-transpeptidases merely act as a tolerance mechanism in this bacterium.
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Dissertations / Theses on the topic "Actinomycetales, infection"

1

Keita, Alpha Kabinet. "Epidémiologie de Tropheryma whipplei." Thesis, Aix-Marseille, 2013. http://www.theses.fr/2013AIXM5044.

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Tropheryma whipplei est détectée avec une prévalence variable dans les selles et de salive. Pour déterminer les facteurs épidémiologiques qui peuvent influencer l'histoire naturelle de la bactérie, nous avons réalisé des études sur l'ensemble de la population de 2 villages au Sénégal (Dielmo et Ndiop), chez les personnes sans domicile fixe (SDF) et dans les familles en France. Dans ces différentes populations, la prévalence du portage de T. whipplei dans les selles était respectivement de 31.2% (139/446), 12,9% (21/162) et 37,5% (24/64). En ce qui concerne les résultats des études phylogénétiques, nous avons identifié au Sénégal 22 génotypes, dont 16 étaient nouveaux. Un seul génotype (53) était commun aux deux villages. Parmi les génotypes spécifiques, l'un (n ° 52) était épidémie à Dielmo (15/28, 53,4%, p <10-3) et l'autre (n ° 49) à Ndiop (27,6%, p = 0,002). Deux génotypes, le génotype 3 et le génotype 85, circulent plus fréquemment chez les SDF par rapport à d'autres groupes personnes positives pour T. whipplei. Au Sénégal, la séroprévalence était estimée à 72,8% (291/400). Dans les familles, la séroprévalence était plus élevée chez les membres (23/30, 77%) par rapport à la population générale (143/300, 48%). Nos résultats montrent que T. whipplei est une bactérie fréquente et contagieuse qui est contractée très tôt dans l'enfance. La mise en évidence de génotypes épidémiques associée à l'absence de la bactérie dans des échantillons d'eau, chez les arthropodes vecteurs; la très faible présence (<1%) dans les selles des animaux domestiques et dans les écouvillons de poussière suggèrent une transmission interhumaine du T whipplei
Tropheryma whipplei is detected with variable prevalence in stool and saliva. To investigate the epidemiological factors which influences the natural history of the bacterium; we performed studies in entire population of 2 villages in Senegal (Dielmo and Ndiop) in homeless people and in family in Marseille-France. In these populations, the prevalence of T. whipplei in stool was respectively 31.2% (139/446), 12.9% (21/162) and 37.5% (24/64).Regarding findings from phylogenetic studies we identified in Senegal 22 genotypes, 16 of which were new. Only one genotype (#53) was common to both villages. Among the specific genotypes, one (#52) was epidemic in Dielmo (15/28, 53.4%, p<10-3) and another (#49) in Ndiop (27.6%, p=0.002). Two genotypes, the genotype 3 and the genotype 85, circulate more frequently in the homeless people compared to other people positive for T. whipplei and are epidemic. The same circulating genotype was significantly more common in families compared to other people. In Senegal, the seroprevalence was estimated at 72.8% (291/400). In family study, the seroprevalence was higher in the relatives (23/30, 77%) compared to the general population (143/300, 48%). Our findings show that T. whipplei is a common and contagious bacterium that is contracted early in childhood. Epidemic genotypes associated with absence of the bacterium in water samples, arthropods vector; almost no presence (< 1%) in domestic animals and dust suggest a human transmission of T whipplei
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2

Rojas-Melo, Nestor S. "Influence of soil and rhizosphere actinomycetes on Frankia infection and nitrogenase activity in Alnus rubra Bong /." 1989. http://hdl.handle.net/1957/11067.

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Khumalo, Lindiwe Lucia. "Isolation and characterisation of antibacterial agents produced by soil bacterium V3." Thesis, 2006. http://hdl.handle.net/10413/990.

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Books on the topic "Actinomycetales, infection"

1

Medical mycology: The pathogenic fungi and the pathogenic actinomycetes. 3rd ed. Philadelphia: Saunders, 1988.

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2

Rojas-Melo, Nestor S. Influence of soil and rhizosphere actinomycetes on Frankia infection and nitrogenase activity in Alnus rubra Bong. 1989.

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The New Paradigm Of Immunity To Tuberculosis. Springer-Verlag New York Inc., 2013.

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Divangahi, Maziar. The New Paradigm of Immunity to Tuberculosis. Springer, 2015.

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