Academic literature on the topic 'Activation of small molecules'

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Journal articles on the topic "Activation of small molecules"

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Dai, Han, Lauren Kustigian, David Carney, et al. "SIRT1 Activation by Small Molecules." Journal of Biological Chemistry 285, no. 43 (2010): 32695–703. http://dx.doi.org/10.1074/jbc.m110.133892.

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Leestemaker, Yves, Annemieke de Jong, Katharina F. Witting, et al. "Proteasome Activation by Small Molecules." Cell Chemical Biology 24, no. 6 (2017): 725–36. http://dx.doi.org/10.1016/j.chembiol.2017.05.010.

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Arnold, Polly L. "Uranium-mediated activation of small molecules." Chemical Communications 47, no. 32 (2011): 9005. http://dx.doi.org/10.1039/c1cc10834d.

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Hinz, Alexander, and Axel Schulz. "Activation of small molecules by biradicaloids." Phosphorus, Sulfur, and Silicon and the Related Elements 191, no. 4 (2016): 578–81. http://dx.doi.org/10.1080/10426507.2015.1128909.

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Yue, Guozong, Rui Gao, Pengxiang Zhao, Mingfu Chu, and Maobing Shuai. "Trivalent Uranium Complex in Small Molecules Activation." Acta Chimica Sinica 74, no. 8 (2016): 657. http://dx.doi.org/10.6023/a16050260.

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Hinz, Alexander, Rene Kuzora, Uwe Rosenthal, Axel Schulz, and Alexander Villinger. "Activation of Small Molecules by Phosphorus Biradicaloids." Chemistry - A European Journal 20, no. 45 (2014): 14659–73. http://dx.doi.org/10.1002/chem.201403964.

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Hesler, Stephen J., Vicky Godoy, and James L. Cole. "Mechanism of PKR Activation by Small Molecules." Biophysical Journal 118, no. 3 (2020): 47a. http://dx.doi.org/10.1016/j.bpj.2019.11.438.

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La Pierre, Henry S., and Karsten Meyer. "ChemInform Abstract: Activation of Small Molecules by Molecular Uranium Complexes." ChemInform 46, no. 12 (2015): no. http://dx.doi.org/10.1002/chin.201512294.

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Vermeeren, Pascal, Michael T. Doppert, F. Matthias Bickelhaupt, and Trevor A. Hamlin. "How metallylenes activate small molecules." Chemical Science 12, no. 12 (2021): 4526–35. http://dx.doi.org/10.1039/d0sc05987k.

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Quantum chemical analyses reveal how model metallylene catalysts activate H<sub>2</sub>. This is the first step towards the rational design of metallylenes for the activation of small molecules and subsequent reactions.
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Ralph, Erik C., Jim Thomson, Jonathan Almaden, and Shaoxian Sun. "Glucose Modulation of Glucokinase Activation by Small Molecules†." Biochemistry 47, no. 17 (2008): 5028–36. http://dx.doi.org/10.1021/bi702516y.

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Dissertations / Theses on the topic "Activation of small molecules"

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Martínez, Rodríguez Luis. "Molecule and catalyst design for recognition and activation of small molecules." Doctoral thesis, Universitat Rovira i Virgili, 2016. http://hdl.handle.net/10803/398693.

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Radzewich, Catherine Ellen. "Activation of small molecules by cationic rhenium complexes /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/11554.

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Lumb, Sean A. "Activation of small molecules by a tungsten-acetylene complex." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0023/NQ38933.pdf.

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Zaher, Hasna. "The activation of small molecules using frustrated Lewis pairs." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:82848f03-2269-4e76-9b01-d89a6d22cd71.

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This thesis describes the activation of small molecules using frustrated Lewis pairs, in particular investigating their use to reduce CO₂ to methanol, thus producing a new route towards a renewable fuel. Chapter One summarises the requirement for a renewable fuel source, the alternative methods currently available and previous research conducted into converting CO₂ to methanol using FLPs and other reducing agents. Chapter Two describes the synthesis of a new family of electron-deficient tris(aryl)boranes, B(C₆F₅)<sub>3-x</sub>(C₆Cl₅)<sub>x</sub> (x = 1-3), allowing the electronic effects, resu
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Falconer, Rosalyn. "Direct activation of small molecules by main group aromatics." Thesis, University of Bristol, 2017. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738515.

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Xing, Junyi. "Activation of small molecules by solid-supported frustrated Lewis pairs." Thesis, University of Oxford, 2017. https://ora.ox.ac.uk/objects/uuid:cb32a5a7-8613-413f-b47c-80674e904c3a.

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The aims of this thesis have been to develop heterogeneous frustrated Lewis pairs for the catalytic activation of small molecules. Frustrated Lewis pairs capable of H<sub>2</sub> activation and CO<sub>2</sub> hydrogenation based on electron-deficient tri-aryl boranes and sterically encumbered phosphines have been immobilised on silica. The reactivity of these heterogeneous systems with small molecules has been tested and compared with a variety of soluble siloxane and silsesquioxane molecular models. The use of layered double hydroxides as a potential support for the immobilisation of FLPs has
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Hu, Jin. "The binding and activation of small molecules by rhenium thiolato-complexes." Thesis, University of Essex, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.306071.

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Lo, Siu Kwan. "Geometry constrained main-group compounds for the activation of small molecules." Thesis, University of Oxford, 2018. http://ora.ox.ac.uk/objects/uuid:6cb24c8a-5e91-4761-b1ef-279ba001681b.

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A series of base-supported group 13 complexes bearing N,N-bis(3,5-di-tert-butyl-2-phenolate)amide pincer ligand, (ONO)<sup>3-</sup>, are reported (E(ONO)·L (E = B, Al, Ga; L = Lewis base). B(ONO) type compounds were formed in-situ and are capable of THF activation. Alternatively, a NMe<sub>3</sub> stabilised boron compound was shown to activate the O-H bond of water and ethanol via frustrated Lewis pair (FLP) type reactivity. The aluminium analogue of E(ONO)·L displays a bimetallic structure in its molecular structure and was shown to be capable of O-H bond cleavage of ethanol across the Al-N
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Najafian, Ahmad. "Activation of Small Molecules by Transition Metal Complexes via Computational Methods." Thesis, University of North Texas, 2020. https://digital.library.unt.edu/ark:/67531/metadc1703353/.

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The first study project is based on modeling Earth abundant 3d transition-metal methoxide complexes with potentially redox-noninnocent ligands for methane C–H bond activation to form methanol (LnM-OMe + CH4 → LnM–Me + CH3OH). Three types of complex consisting of tridentate pincer terpyridine-like ligands, and different first-row transition metals (M = Ti, V, Cr, Mn, Fe, Co, Ni, and Cu) were modeled to elucidate the reaction mechanism as well as the effect of the metal identity on the thermodynamics and kinetics of a methane activation reaction. The calculations showed that the d electron count
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Guérin, Frédéric. "Pyridine diamide complexes of early transition metals, activation of small organic molecules." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp03/NQ27151.pdf.

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Books on the topic "Activation of small molecules"

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Azuma, Miyuki, and Hideo Yagita, eds. Co-signal Molecules in T Cell Activation. Springer Singapore, 2019. http://dx.doi.org/10.1007/978-981-32-9717-3.

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service), SpringerLink (Online, ed. Small Molecules in Oncology. Springer-Verlag Berlin Heidelberg, 2010.

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Martens, Uwe M., ed. Small Molecules in Oncology. Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-01222-8.

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Martens, Uwe M., ed. Small Molecules in Oncology. Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-54490-3.

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Martens, Uwe M., ed. Small Molecules in Hematology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-91439-8.

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Martens, Uwe M., ed. Small Molecules in Oncology. Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-91442-8.

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Osada, Hiroyuki, ed. Protein Targeting with Small Molecules. John Wiley & Sons, Inc., 2009. http://dx.doi.org/10.1002/9780470495018.

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Sitter, Helmut, Claudia Draxl, and Michael Ramsey, eds. Small Organic Molecules on Surfaces. Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-33848-9.

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Ribbe, Markus W., ed. Metallocofactors that Activate Small Molecules. Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-25897-9.

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Lin, He. Mass spectrometry imaging of small molecules. Humana Press, 2014.

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Book chapters on the topic "Activation of small molecules"

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Tye, Jesse W., Marcetta Y. Darensbourg, and Michael B. Hall. "The Activation of Dihydrogen." In Activation of Small Molecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/9783527609352.ch4.

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Berreau, Lisa M. "Water Activation: Catalytic Hydrolysis." In Activation of Small Molecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/9783527609352.ch8.

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Aresta, Michele. "Carbon Dioxide Reduction and Uses as a Chemical Feedstock." In Activation of Small Molecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/9783527609352.ch1.

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Lee, Dong-Heon, Biplab Mondal, and Kenneth D. Karlin. "Nitrogen Monoxide and Nitrous Oxide Binding and Reduction." In Activation of Small Molecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/9783527609352.ch2.

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Peters, Jonas C., and Mark P. Mehn. "Bio-organometallic Approaches to Nitrogen Fixation Chemistry." In Activation of Small Molecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/9783527609352.ch3.

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Cornell, Candace N., and Matthew S. Sigman. "Molecular Oxygen Binding and Activation: Oxidation Catalysis." In Activation of Small Molecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/9783527609352.ch5.

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Borovik, Andrew S., Paul J. Zinn, and Matthew K. Zart. "Dioxygen Binding and Activation: Reactive Intermediates." In Activation of Small Molecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/9783527609352.ch6.

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Conley, Brian L., William J. Tenn, Kenneth J. H. Young, et al. "Methane Functionalization." In Activation of Small Molecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/9783527609352.ch7.

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van Leeuwen, Piet W. N. M., and Zoraida Freixa. "Carbon Monoxide as a Chemical Feedstock: Carbonylation Catalysis." In Activation of Small Molecules. Wiley-VCH Verlag GmbH & Co. KGaA, 2006. http://dx.doi.org/10.1002/9783527609352.ch9.

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Massudi, Hassina, Lindsay E. Wu, and David A. Sinclair. "Sirtuin Activation by Small Molecules." In Sirtuins. Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-024-0962-8_12.

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Conference papers on the topic "Activation of small molecules"

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Ma, Shengqian. "Tailored Metal-Organic Frameworks for Photocatalytic Small Molecule Activation." In nanoGe Spring Meeting 2022. Fundació Scito, 2022. http://dx.doi.org/10.29363/nanoge.nsm.2022.109.

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Mitchell, Dominique C., Jin Liu, Zheng Wang, et al. "Abstract 5228: Small molecule activation of the LKB1 tumor suppressor." In Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA. American Association for Cancer Research, 2020. http://dx.doi.org/10.1158/1538-7445.am2020-5228.

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Reyna, Denis, Thomas Garner, Andrea Lopez, et al. "Abstract 951: Direct small-molecule BAX activation in acute myeloid leukemia." In Proceedings: AACR Annual Meeting 2018; April 14-18, 2018; Chicago, IL. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.am2018-951.

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Astudillo, Luisana, and Anthony J. Capobianco. "Abstract A39: A small molecule inhibitor of the Notch transcriptional activation complex." In Abstracts: AACR Precision Medicine Series: Targeting the Vulnerabilities of Cancer; May 16-19, 2016; Miami, FL. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1557-3265.pmccavuln16-a39.

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Damodaran, Chendil, Ashish Tyagi, Balaji Chandrasekaran, et al. "Abstract 2014: A novel small molecule inhibitor to suppress Notch1 activation in CRC." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-2014.

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Astudillo, Luisana, and Anthony Capobianco. "Abstract 196: Identification of small molecule inhibitors of the notch transcriptional activation complex." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-196.

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Lehal, Rajwinder, Viktoras Frismantas, Sylvain Loubéry, et al. "Abstract 338: A novel small molecule inhibitor of the Notch transcription activation complex." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-338.

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Damodaran, Chendil, Ashish Tyagi, Balaji Chandrasekaran, et al. "Abstract 2014: A novel small molecule inhibitor to suppress Notch1 activation in CRC." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-2014.

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Ghezzi, Diego, Andrea Menegon, Alessandra Pedrocchi, Sara Mantero, Flavia Valtorta, and Giancarlo Ferrigno. "PhotoMEA: A New Step Towards Total Optical Analysis of In Vitro Neuronal Networks." In ASME 8th Biennial Conference on Engineering Systems Design and Analysis. ASMEDC, 2006. http://dx.doi.org/10.1115/esda2006-95218.

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Light stimulation of neurons is a promising approach for investigating the molecular mechanisms at the basis of neuronal physiology and plasticity. In particular, flash photolysis of caged compounds offers the unique advantage of allowing to quickly change the concentration of either intracellular or extracellular bioactive molecules, such as neurotransmitters or second messengers, for the stimulation or modulation of neuronal activity. In this field of research, we describe a simple laser-based set-up for the local activation of caged compounds. The coupling of a UV laser diode to a small-cor
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Singh, Kriti, Ravi Shashi Nayana Munuganti, Eric Leblanc, Artem Cherkasov та Paul S. Rennie. "Abstract 2521: Small molecule inhibitors targeting the activation function-2 site of estrogen receptor-α". У Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-2521.

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Reports on the topic "Activation of small molecules"

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Ford, Peter C. Studies Relevent to Catalytic Activation Co & other small Molecules. Office of Scientific and Technical Information (OSTI), 2005. http://dx.doi.org/10.2172/839381.

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Nocera, Daniel G. Hangman Catalysis for Photo–and Photoelectro–Chemical Activation of Water Proton-Coupled Electron Transfer Mechanisms of Small Molecule Activation. Office of Scientific and Technical Information (OSTI), 2013. http://dx.doi.org/10.2172/1367667.

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Betley, Theodore A. Early Career: Catalyst design for small molecule activation of energy consequence Final Report. Office of Scientific and Technical Information (OSTI), 2018. http://dx.doi.org/10.2172/1427472.

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Mindiola, Daniel J. Synthesis and Exploratory Catalysis of 3d Metals: Group-Transfer Reactions, and the Activation and Functionalization of Small Molecules Including Greenhouse Gases. Office of Scientific and Technical Information (OSTI), 2014. http://dx.doi.org/10.2172/1130753.

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Mindiola, Daniel. Synthesis and Exploratory Catalysis of 3d Metals: Atom and Group-Transfer Reactions and the Activation and Functionalization of Small Molecules Including Greenhouse Gases. Office of Scientific and Technical Information (OSTI), 2020. http://dx.doi.org/10.2172/1843640.

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Thomas, Christine M. Early-Late Heterobimetallic Complexes Linked by Phosphinoamide Ligands. Tuning Redox Potentials and Small Molecule Activation. Office of Scientific and Technical Information (OSTI), 2015. http://dx.doi.org/10.2172/1212862.

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Hergenrother, Paul J. Small Molecule Activation of Procaspase-2 for the Selective Induction of Apoptotic Death in Breast Cancer Cells. Defense Technical Information Center, 2007. http://dx.doi.org/10.21236/ada478328.

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Thomas, Christine, Bing Wu, Gursu Culcu, et al. Metal-Metal Interactions in Heterobimetallic Complexes as a Strategy to Promote Multielectron Redox And Small Molecule Activation Processes. Office of Scientific and Technical Information (OSTI), 2019. http://dx.doi.org/10.2172/1575282.

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Kellman, Michael E. Chaotic Spectra of Small Molecules. Defense Technical Information Center, 1990. http://dx.doi.org/10.21236/ada231638.

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Boydston, Andrew J. Mechanochemical Activation of Small Ring Cyclopolymers. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada617738.

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