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Journal articles on the topic 'Active uterine contraction'

Author: Grafiati

Published: 14 December 2024

Last updated: 31 July 2025

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1

Weiner, C. P., L. P. Thompson, K. Z. Liu, and J. E. Herrig. "Pregnancy reduces serotonin-induced contraction of guinea pig uterine and carotid arteries." American Journal of Physiology-Heart and Circulatory Physiology 263, no. 6 (1992): H1764—H1769. http://dx.doi.org/10.1152/ajpheart.1992.263.6.h1764.

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Because platelet activation and serotonin have been implicated in preeclamptic hypertension, we investigated the effect of pregnancy on the contractile response to this agent. Prior studies have shown that the vascular contractions to norepinephrine, angiotensin II, and thromboxane are reduced during normal pregnancy by the altered release of endothelium-derived vasoactive substances. We hypothesized that the contraction to serotonin would also be reduced during pregnancy by an endothelium-dependent mechanism. Isolated ring segments from uterine and carotid arteries of near-term pregnant and n

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Chiang, Yi-Fen, Hui-Chih Hung, Hsin-Yuan Chen, et al. "The Inhibitory Effect of Extra Virgin Olive Oil and Its Active Compound Oleocanthal on Prostaglandin-Induced Uterine Hypercontraction and Pain—Ex Vivo and In Vivo Study." Nutrients 12, no. 10 (2020): 3012. http://dx.doi.org/10.3390/nu12103012.

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Primary dysmenorrhea is a common occurrence in adolescent women and is a type of chronic inflammation. Dysmenorrhea is due to an increase in oxidative stress, which increases cyclooxygenase-2 (COX-2) expression, increases the concentration of prostaglandin F2α (PGF2α), and increases the calcium concentration in uterine smooth muscle, causing excessive uterine contractions and pain. The polyphenolic compound oleocanthal (OC) in extra virgin olive oil (EVOO) has been shown to have an anti-inflammatory and antioxidant effect. This study aimed to investigate the inhibitory effect of extra virgin o

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Rita Aninora, Novia, Joserizal Seridji, and Meilinda Agus. "Correlation of Calcium Levels With The Strenght of Uterus Contraction on The Active Phase of First Stage Labor." Journal of Midwifery 3, no. 2 (2018): 76. http://dx.doi.org/10.25077/jom.3.2.76-83.2018.

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Contributing factor to uterus contraction mechanism is the imbalance of the extracellular calcium level. When extracellular calcium level is inadequate, response of the myometrium to oxytocin decreased and the calcium influx inter-cell membranes are suppressed, thus inhibit uterine contractions. The aim of this research is to know the correlation between levels of calcium and the strength of uterine contraction in the active phase of first stage labor. This was a cross-sectional analytic correlative study in the Dr. Rasidin Hospital Padang and UPTD Health Laboratory in West Sumatra province, i

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Ducros, Laurent, Philippe Bonnin, Bernard P. Cholley, et al. "Increasing Maternal Blood Pressure with Ephedrine Increases Uterine Artery Blood Flow Velocity during Uterine Contraction." Anesthesiology 96, no. 3 (2002): 612–16. http://dx.doi.org/10.1097/00000542-200203000-00017.

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Background During labor, ephedrine is widely used to prevent or to treat maternal arterial hypotension and restore uterine perfusion pressure to avoid intrapartum fetal asphyxia. However, the effects of ephedrine on uterine blood flow have not been studied during uterine contractions. The purpose of the study was to assess the effects of ephedrine on uterine artery velocities and resistance index using the Doppler technique during the active phase of labor. Methods Ten normotensive, healthy parturients with uncomplicated pregnancies at term received intravenous ephedrine during labor to increa

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Burton, M. J., H. E. Dziuk, M. L. Fahning, and R. Zemjanis. "Myometrial activity during natural and dexamethasone-induced parturition in the cow." American Journal of Veterinary Research 48, no. 1 (1987): 37–44. https://doi.org/10.2460/ajvr.1987.48.01.37.

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SUMMARY Myometrial activity was monitored during natural and dexamethasone-induced parturition in 8 Holstein dairy cattle, using strain gauge transducers. Four gauges were attached to the serosal surface of the gravid uterine horn, dividing it into thirds. Parturition was induced in 2 of 4 heifers and 2 of 4 cows (group 1); the remaining animals were allowed to calve spontaneously (group 2). Chains of low-amplitude contractions (repeated small deviations from base line) were detected before parturition was induced, and these were more common at distended parts of the uterus. Uncharacteristical

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Kuzminykh, Tatyana U., Vera Yu Borisova, Igor P. Nikolayenkov, Georgy R. Kozonov, and Gulrukhsor Kh Tolibova. "Role of biologically active molecules in uterine contractile activity." Journal of obstetrics and women's diseases 68, no. 1 (2019): 21–27. http://dx.doi.org/10.17816/jowd68121-27.

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Hypothesis/aims of study. Myometrial relaxation and contraction require synchronous cellular interactions. At present, it has been established that the coordination of myometrial contractile activity is carried out by a conduction system constructed from gap junctions with intercellular channels. There are no clinical data on inhibiting (nitric oxide synthase) and activating (connexin-43) factors of uterine contractile activity in the myometrium during pregnancy and parturition in the published literature. This study was undertaken to measure the expression levels of nitric oxide synthase, adh

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Kim, Dong Joon, Young Joon Ki, Bo Hyun Jang, Seongcheol Kim, Sang Hun Kim, and Ki Tae Jung. "Clinically relevant concentrations of dexmedetomidine may reduce oxytocin-induced myometrium contractions in pregnant rats." Anesthesia and Pain Medicine 15, no. 4 (2020): 451–58. http://dx.doi.org/10.17085/apm.20036.

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Background: Recently, there have been some trials to use dexmedetomidine in the obstetric field but concerns regarding the drug include changes in uterine contractions after labor. We aimed to evaluate the effects of dexmedetomidine on the myometrial contractions of pregnant rats.Methods: In a pilot study, the contraction of the myometrial strips of pregnant Sprague-Dawley rats in an organ bath with oxytocin at 1 mU/ml was assessed by adding dexmedetomidine from 10-6 to 10-2 M accumulatively every 20 min, and active tension and the number of contractions were evaluated. Then, changes in myomet

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Shin, Young K., Young D. Kim, and Joseph V. Collea. "The Effect of Propofol on Isolated Human Pregnant Uterine Muscle." Anesthesiology 89, no. 1 (1998): 105–9. http://dx.doi.org/10.1097/00000542-199807000-00017.

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Background Propofol is an alternative to thiopental as an intravenous induction agent for cesarean section. Because it has relaxant effects on vascular and other smooth muscles, the authors set out to determine whether propofol has any effect on pregnant human uterine smooth muscle in an isolated preparation. Methods Myometrial specimens were excised from 10 parturients undergoing elective cesarean section. The muscle strips were suspended in tissue baths and isometric tension was recorded. After establishment of rhythmic contractions in the buffer solution as a control, propofol (0.5 to 10 mi

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Setiawati, Intan, Santi Sofiyanti, and Diyan Indrayani. "INTRAPARTUM NIPPLE STIMULATION TO INCREASE CONTRACTION IN PRIMIPARITY: EVIDENCE BASED CASE REPORT." INTERNATIONAL CONFERENCE ON INTERPROFESSIONAL HEALTH COLLABORATION AND COMMUNITY EMPOWERMENT 5, no. 2 (2024): 251–55. http://dx.doi.org/10.34011/icihcce.v5i2.292.

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Introduction Normal labor process duration varies between 4 to 24 hours since the occurrence of uterine contractions which cause changes in the cervix. Adequate contractions are needed to induce labor to proceed normally. The active phase of the first stage of labor is considered more tiring and painful because uterine activity increases. In this phase, there is often an increase in adrenaline production which has the potential to inhibit contractions and delay the labor process. Nipple stimulation is one method that can be used to increase uterine contractions. This technique can stimulate th

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Dabiré, Prosper A., Youssoufou Ouédraogo, Abel A. Somé, et al. "Relaxant Effects of the Aqueous Extract of Excoecaria grahamii (Euphorbiaceae) Leaves on Uterine Horn Contractility in Wistar Rats." BioMed Research International 2021 (April 9, 2021): 1–8. http://dx.doi.org/10.1155/2021/6618565.

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In uterine smooth muscle, the effects of Excoecaria grahamii are not yet documented. To fill this gap, we investigated the pharmacological effect of Excoecaria grahamii on the contraction of the rat isolated uterine horns. The isolated segments were exposed to different concentrations of the aqueous extract of Excoecaria grahamii leaves and pharmacological drugs. The results showed that Excoecaria grahamii aqueous extract decreased the amplitude and frequency by concentration-related manner. I C 50 values were 2.4 and 2.6, respectively, for amplitude and frequency. Our study revealed that the

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Mazoni, Simone Roque, Emilia Campos de Carvalho, and Cláudia Benedita dos Santos. "Clinical validation of the nursing diagnosis labor pain." Revista Latino-Americana de Enfermagem 21, spe (2013): 88–96. http://dx.doi.org/10.1590/s0104-11692013000700012.

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OBJECTIVE: The study intends to identify the presence of clinical indicators of pain during labor and to correlate the verbal reference of pain intensity with uterine contractions as a proposal to validate the clinical nursing diagnosis Labor Pain. METHOD: Observational study of the 22 clinical indicators that represented the defining characteristics for the diagnosis. RESULTS: There were 55 participants in labor (18 in the initial active stage, 6 in the final active stage and 31 in both stages), over 18 years old, in their first pregnancy, with effective contractions and cervical dilation of

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Huang, Yun-Ju, Yu-Chieh Chen, Hsin-Yuan Chen, et al. "Ethanolic Extracts of Adlay Testa and Hull and Their Active Biomolecules Exert Relaxing Effect on Uterine Muscle Contraction through Blocking Extracellular Calcium Influx in Ex Vivo and In Vivo Studies." Biomolecules 11, no. 6 (2021): 887. http://dx.doi.org/10.3390/biom11060887.

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Dysmenorrhea is one of the most prevalent disorders in gynecology. Historically, adlay (Coix lachryma-jobi L. var. Ma-yuen Stapf.) has been explored for its anti-tumor, pain relief, anti-inflammatory, and analgesic effects. The aim of this study was to evaluate the effects of adlay seeds on the inhibition of uterine contraction and thus dysmenorrhea relief, in vitro and in vivo. HPLC-MS and GC were used to elucidate the ethyl acetate fraction of adlay testa ethanolic extract (ATE-EA) and ethyl acetate fraction of adlay hull ethanolic extract (AHE-EA). Elucidation yielded flavonoids, phytostero

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13

Su, Shulan, Yongqing Hua, Jin-Ao Duan, Wei Zhou, Erxin Shang, and Yuping Tang. "Inhibitory Effects of Active Fraction and Its Main Components of Shaofu Zhuyu Decoction on Uterus Contraction." American Journal of Chinese Medicine 38, no. 04 (2010): 777–87. http://dx.doi.org/10.1142/s0192415x10008238.

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Shaofu Zhuyu decoction is a famous formula for treating primary dysmenorrhea in China since the Qing dynasty. In this paper, the inhibitory effects of active-guided fraction and its main bioactive components of Shaofu Zhuyu decoction on a model of non-pregnant mice uterine contraction induced by oxytocin in vitro were investigated. Qualitative and quantitative chemical analyses were used to correlate the chemical composition of active fraction with the spasmolytic effects. Seven ingredients in the active fraction were identified and quantified by HPLC-DAD. Three ingredients, ferulic acid, vani

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de Sotomayor, M. Alvarez, M. D. Herrera, C. Perez-Guerrero, and E. Marhuenda. "Uterine Relaxant Effect of Zolpidem: A Comparison with Other Smooth Muscle Relaxants." Zeitschrift für Naturforschung C 52, no. 9-10 (1997): 687–93. http://dx.doi.org/10.1515/znc-1997-9-1018.

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Zolpidem is an imidazopyridine sedative-hypnotic which interacts with central benzodiazepine- receptors. To examine its effects on uterine smooth muscle we have compared with those obtained by diltiazem, papaverine and diazepam on different experimental models. The IC50 values obtained indicate similar behaviour of zolpidem and diazepam. They showed more active against the spontaneous contractions and those induced by KCl (60 mᴍ) or by CaCl2 (0.01-10 mᴍ) in Ca2+-free depolarizing medium than against acetylcholine (0.1 mᴍ)-induced contractions. Both of them also showed more effectiveness agains

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15

Mudrov, Viktor A. "Abnormal labor as a medical and social issue." Journal of obstetrics and women's diseases 70, no. 5 (2021): 117–30. http://dx.doi.org/10.17816/jowd78295.

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Abnormal labor is a main cause of obstetric and perinatal complications. Impaired uterine contraction during childbirth is accompanied by an increase in the risk of fetal asphyxia, obstetric bleeding and postpartum inflammatory diseases. The frequency of diagnosed abnormal uterine contractile activity is 10-25%, which, along with the high need for operative delivery, allows for considering abnormal labor as one of the main medical and social issues of the present time. The aim of this study was to consider abnormal labor as a medical and social problem. This was achieved by using an analytical

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Sun, Shanshan, Zhen Ye, and Wenjun Wang. "Practical Effect of Cervical Softening Decoction Combined with Delivery Ball Approach in Promoting Vaginal Delivery in Primiparous Women." Journal of Biobased Materials and Bioenergy 17, no. 6 (2023): 774–82. http://dx.doi.org/10.1166/jbmb.2023.2326.

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In Traditional Chinese Medicine, Cervical Softening Decoction is derived from a modified “Wan Bing Hui Chun” formulation and consists of natural herbal ingredients such as Angelica sinensis, Ligusticum chuanxiong, Leonurus heterophyllus, and Cortex Daphnes. The decoction regulates Qi, promotes blood circulation, and facilitates fetus descent. Genkwanin is an active compound in L. heterophyllus and previous studies identified this compound in ethanolic extracts from rat uterine smooth muscle cell membrane fractions. To further understand the pharmacological activities of Cervical Softening Deco

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Yu, Y., B. Q. Lin, L. Yu, Y. Q. Hua, J. A. Duan, and S. P. Li. "Inhibitory Effects of Two Ferulates from Angelica Sinensis on Platelet Aggregation and Oxytocin-induced Uterine Contraction." Open Bioactive Compounds Journal 2, no. 1 (2009): 43–46. http://dx.doi.org/10.2174/1874847300902010043.

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Ferulic acid (FA) is widely considered as a biologically active component in Angelica sinensis, and used as one of the marker compounds for the quality control of Angelica sinensis. However, in A. sinensis, FA mainly exists as its ester, coniferyl ferulate (CF). CF is unstable and readily hydrolyzed into FA during conventional extraction. Herein, their antiplatelet aggregation activities and relaxant effects on oxytocin-induced mouse uterine muscle contraction were investigated and compared. The results showed that FA inhibited arachidonic acid (AA), adenosine diphosphate (ADP) and thrombin (T

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Khalil, Raouf A., and Joey P. Granger. "Vascular mechanisms of increased arterial pressure in preeclampsia: lessons from animal models." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 283, no. 1 (2002): R29—R45. http://dx.doi.org/10.1152/ajpregu.00762.2001.

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Normal pregnancy is associated with reductions in total vascular resistance and arterial pressure possibly due to enhanced endothelium-dependent vascular relaxation and decreased vascular reactivity to vasoconstrictor agonists. These beneficial hemodynamic and vascular changes do not occur in women who develop preeclampsia; instead, severe increases in vascular resistance and arterial pressure are observed. Although preeclampsia represents a major cause of maternal and fetal morbidity and mortality, the vascular and cellular mechanisms underlying this disorder have not been clearly identified.

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Alanazi, Hamad Huran F., Ali Mohammed S. Alqarni, Abdullah Abdulqader H. Alamri, et al. "Postpartum hemorrhage management and nursing care interventions: An updated review." International journal of health sciences 5, S1 (2021): 1456–72. http://dx.doi.org/10.53730/ijhs.v5ns1.15385.

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Background: Postpartum hemorrhage (PPH) is a leading cause of maternal mortality globally, contributing to approximately 27.1% of maternal deaths. The primary cause of PPH is uterine atony, characterized by the failure of the uterus to contract after childbirth. Despite active management strategies like exogenous oxytocin administration, PPH rates have not significantly decreased, and there is growing evidence suggesting adverse effects from medical interventions such as oxytocin. Alternative methods like skin-to-skin contact (SSC) and early breastfeeding have emerged as promising preventive m

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Prastyoningsih, Aris, Siti Wahyuni, Christin Bumi Pangesti, and Dwi Margareta Andini. "Pengaruh Pemberian Akupresur terhadap Nyeri Persalinan Fase Aktif." Oksitosin : Jurnal Ilmiah Kebidanan 11, no. 1 (2024): 73–82. http://dx.doi.org/10.35316/oksitosin.v11i1.4573.

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Contraction pain is main problem for patients in the 1st stage of labor in active phase. Labor pain in first stage of the active phase can be treated with acupressure at points L14 and SP6. The L14 and SP6 acupressure points can stimulate release of hormone oxytocin from pituitary, which will stimulate uterine contractions, thereby helping the labor process to be better and reducing pain during labor. The aim of this study was to determine how acupressure impacts labor pain during active phase of the first stage. Design of this research is one group pre-post test. This study involved 30 women

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White, B. G., S. J. Williams, K. Highmore, and D. J. MacPhee. "Small heat shock protein 27 (Hsp27) expression is highly induced in rat myometrium during late pregnancy and labour." Reproduction 129, no. 1 (2005): 115–26. http://dx.doi.org/10.1530/rep.1.00426.

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The underlying mechanisms that regulate uterine contractions during labour are still poorly understood. A candidate regulatory protein is heat shock protein 27 (Hsp27). It belongs to the small heat shock protein family and can regulate actin cytoskeleton dynamics, act as a chaperone, and may regulate contractile protein activation. As a result, we hypothesized that Hsp27 expression would be highly induced during late pregnancy and labour. Hsp27 mRNA expression was significantly elevated (P< 0.05) on days 17 to 22 of gestation. In addition, immunoblot analysis demonstrated that detection of

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Engstrom, T., P. Bratholm, H. Vilhardt, and NJ Christensen. "Beta2-adrenoceptor desensitization in non-pregnant estrogen-primed rat myometrium involves modulation of oxytocin receptor gene expression." Journal of Molecular Endocrinology 20, no. 2 (1998): 261–70. http://dx.doi.org/10.1677/jme.0.0200261.

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The nona-peptide oxytocin (OT) induces contraction of the myometrium by interaction with specific plasma membrane associated OT receptors (OTR), whereas stimulation of beta2-adrenoceptors (beta2AR) causes relaxation. Homologous desensitization of the myometrium to both hormones has been described. However, a possible interaction between the two systems has not been investigated. In the present study, long-term in vivo treatment of non-pregnant estrogen-primed rats with isoproterenol decreased maximal relaxation of isolated uterine strips challenged with isoproterenol. Increased EC50 values of

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Ashraf, F., Pervin Akther, N. Yasmin, et al. "Carbetocin versus Oxytocin in Active Management of 3rd stage of Labour following Vaginal Delivery." Bioresearch Communications 7, no. 1 (2021): 927–31. http://dx.doi.org/10.3329/brc.v7i1.54247.

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Background: Every day more than 220 women around the world die from severe bleeding after childbirth. Globally post-partum hemorrhage is the number one direct cause of maternal mortality. Most postpartum hemorrhages are caused by uterine atony and occur in the immediate postpartum period. Most of these tragic deaths can be prevented by active management of third stage of labour. Active management of the third stage of labor should be practiced routinely to decrease the risk of postpartum hemorrhage. Oxytocin is used for enhancing uterine contraction after delivery. But oxytocin has some limita

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Irawati, Ayu, Susianti Susianti, and Iranita Haryono. "Mengurangi Nyeri Persalinan dengan Teknik Birthing Ball." Jurnal Bidan Cerdas 2, no. 1 (2020): 15–22. http://dx.doi.org/10.33860/jbc.v2i1.78.

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Pain during labor is caused by the first stage of labor in which contractions cause dilation and thinning of the cervix and uterine ischemia due to contraction of the myometrial arteries. These contractions cause the opening of the cervix to begin labor. Various attempts are made to reduce labor pain, both pharmacologically and non-pharmacological. The non-pharmacological method applied is a distraction with birth balls. The research aims to prove the effectiveness of the use of birthing ball on the reduction of labor pain in the first stage of labor in the active phase. This study used an exp

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Lee, Ji Hwan, Sullim Lee, Quynh Nhu Nguyen, et al. "Identification of the Active Ingredient and Beneficial Effects of Vitex rotundifolia Fruits on Menopausal Symptoms in Ovariectomized Rats." Biomolecules 11, no. 7 (2021): 1033. http://dx.doi.org/10.3390/biom11071033.

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Estrogen replacement therapy is a treatment to relieve the symptoms of menopause. Many studies suggest that natural bioactive ingredients from plants resemble estrogen in structure and biological functions and can relieve symptoms of menopause. The fruit of V. rotundifolia, called “Man HyungJa” in Korean, is a traditional medicine used to treat headache, migraine, eye pain, neuralgia, and premenstrual syndrome in Korea and China. The aim of the present study was to confirm that V. rotundifolia fruit extract (VFE) exerts biological functions similar to those of estrogen in menopausal syndrome.

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Ebrahimzadeh, Samira, Nahid Golmakani, Maryam Kabirian, and Mohhamad T. Shakeri. "Study of correlation between maternal fatigue and uterine contraction pattern in the active phase of labour." Journal of Clinical Nursing 21, no. 11-12 (2012): 1563–69. http://dx.doi.org/10.1111/j.1365-2702.2012.04084.x.

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Althaus, Janyne E., Scott Petersen, Rita Driggers, Alice Cootauco, Jessica L. Bienstock, and Karin J. Blakemore. "Cephalopelvic disproportion is associated with an altered uterine contraction shape in the active phase of labor." American Journal of Obstetrics and Gynecology 195, no. 3 (2006): 739–42. http://dx.doi.org/10.1016/j.ajog.2006.05.053.

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Ophir, Ella, Jacob Bornstein, Marwan Odeh, et al. "Labor progress indices and dynamics of the individual uterine contraction during the active stage of labor." Journal of Obstetrics and Gynaecology Research 40, no. 3 (2013): 686–93. http://dx.doi.org/10.1111/jog.12218.

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Afrooz, Rowshan, Abul Kalam Md Faruq, and Mitheel Ibna Islam. "Pre-labour Rapture of Membrane at Term in Patients with an Unfavorable Cervix: Active verses Conservative Management." Ibrahim Cardiac Medical Journal 5, no. 1-2 (2017): 35–39. http://dx.doi.org/10.3329/icmj.v5i1-2.53700.

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Objective: The present quasi-experimental (comparative clinical trial) study was conducted to compare the outcome of active versus conservative management in patients with prelabour rupture of membrane (PROM) at term with an unfavourable cervix. Materials & Methods: The study was carried out at Gynae & Obstetrics Department, Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka over a period of 12 months from July 2009 to June 2010. Women admitted in the Obstetrics & Gynaecology Ward of BSMMU with pre-mature rupture of membrane (PROM) at term with unfavourable cervix was

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Aguilar, Hector, and B. F. (Peter) Mitchell. "The role of THOA in calcium sensitization in human myometrial smooth muscles." Clinical & Investigative Medicine 30, no. 4 (2007): 70. http://dx.doi.org/10.25011/cim.v30i4.2836.

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Improved understanding of the regulation of contractions of uterine smooth muscle (myometrium) is essential to develop more successful strategies for prevention of premature birth, which remains the most common cause of infant death and disability. Oxytocin (OT) and prostaglandin (PG) F2a are potent myometrial stimulants which induce an increase in intracellular Ca++. This activates myosin light chain kinase (MLCK) and subsequently the cell’s contractile machinery. However, there is poor correlation between the rise in Ca++ and the strength of the myometrial contraction. Contractile strength g

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Irawati, Ayu, Susanti Susanti, and Iranita Haryono. "Mengurangi Nyeri Persalinan dengan Teknik Birthing Ball." Jurnal Bidan Cerdas (JBC) 2, no. 3 (2019): 129. http://dx.doi.org/10.33860/jbc.v2i3.282.

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Childbirth and birth is a physiological process that must be experienced by a mother. Pain during labor is caused by the first stage of labor in which contractions cause dilation and thinning of the cervix and uterine ischemia due to contraction of the myometrial arteries. These contractions cause the opening of the cervix to begin labor. Various attempts are made to reduce labor pain, both pharmacologically and non-pharmacological. The non-pharmacological method applied is a distraction with birth balls. The research aims to prove the effectiveness of the use of birthing ball on the reduction

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Herlina and Nining Sriningsih. "Pengaruh Aromaterapi Lemon Dan Relaksasi Genggam Jari Terhadap Penurunan Nyeri Persalinan Fase Aktif Lampung Selatan." Jurnal Vokasi Keperawatan (JVK) 6, no. 1 (2023): 100–108. http://dx.doi.org/10.33369/jvk.v6i1.26924.

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The uterine contraction and complete opening (10 cm) can cause pain in birthing stage I of active phase. The objective of this research was to find out the influence of lemonade aroma and holding fingers relaxation therapies to reduce pain of birthing stage I of active phase in Seloretno village midwifery clinic in Sidomulyo sub district of South Lampung district in 2020. This was quantitative research by using a pre-experiment approach and one group pretest-posttest design. Population was 22 birthing mothers stage I in active phase in Seloretno village midwifery clinic. Samples were of total

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Tsymbalyuk, Olga, Tetyana Veklich, Oleksandr Maliuk, Sergiy Cherenok, Vitaly Kalchenko, and Sergiy Kosterin. "Kinetic regularities of thiacalix[4]arene C-1193 action on Na+, K+-ATPase activity of the plasma membrane and contractile activity of the myometrium." Studia Biologica 19, no. 1 (2025): 15–34. https://doi.org/10.30970/sbi.1901.816.

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Background. Nа+, K+-ATPase (sodium pump) is an electrogenic Са2+-independent Mg2+, Na+, K+-ATP-dependent transporting system of plasma membrane (PM), which conducts active transfer of univalent ions of Na and K and thus maintains their electrochemical gradients, required for normal functioning of the cell. It was proven that in some widesperad pathologies the activity of the sodium pump is disrupted. Therefore, the search for effectors - selective inhibitors and activators that would be able to specifically affect Na+, K+-ATPase, restoring its activity in pathological conditions, is very promi

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Tsymbalyuk, Olga, Tetyana Veklich, Oleksandr Maliuk, Sergiy Cherenok, Vitaly Kalchenko, and Sergiy Kosterin. "Kinetic regularities of thiacalix[4]arene C-1193 action on Na+, K+-ATPase activity of the plasma membrane and contractile activity of the myometrium." Studia Biologica 19, no. 1 (2025): 15–34. https://doi.org/10.30970/sbi.1901.808.

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Background. Nа+, K+-ATPase (sodium pump) is an electrogenic Са2+-independent Mg2+, Na+, K+-ATP-dependent transporting system of plasma membrane (PM), which conducts active transfer of univalent ions of Na and K and thus maintains their electrochemical gradients, required for normal functioning of the cell. It was proven that in some widesperad pathologies the activity of the sodium pump is disrupted. Therefore, the search for effectors - selective inhibitors and activators that would be able to specifically affect Na+, K+-ATPase, restoring its activity in pathological conditions, is very promi

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Shashi Bharti, Sushma, and Vidya Sagar Ram. "Exploring the Ayurvedic Practice of Potaki Taila Pichu for Labor Facilitation among Rural Women in Northern Indi." Journal of Ayurveda and Integrated Medical Sciences 9, no. 4 (2024): 40–45. http://dx.doi.org/10.21760/jaims.9.4.6.

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Introduction: Childbirth is a profound experience in a woman's life, emphasizing the importance of promoting natural birthing processes to minimize discomfort and medical intervention. Ayurveda, an ancient holistic medical system, advocates for safe motherhood through herbal interventions like Potaki (Basella alba) Taila Pichu, which aims to alleviate imbalances in Apana Vayu and facilitate smooth labor. Methods: This study evaluated the efficacy of Potaki Taila Pichu in promoting easier labor by assessing its impact on cervical dilation and effacement. Sixty pregnant women meeting inclusion c

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Fadila Septi Hasanah and Nova Yulita. "Efektivitas Penekanan Titik Akupresur Terhadap Pengurangan Nyeri Persalinan." Protein : Jurnal Ilmu Keperawatan dan Kebidanan. 2, no. 4 (2024): 338–42. https://doi.org/10.61132/protein.v2i4.817.

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Labor pain occurs due to the contraction of uterine muscles, which can cause discomfort and pain for the mother, potentially affecting the labor process. Acupressure is a complementary therapy that involves applying pressure or massage and stimulation at specific points on the body. The purpose of this study is to determine the effectiveness of acupressure point pressure in reducing labor pain for Mrs. N at PMB Silvi Ayu, S.Keb in Pekanbaru. This research used a descriptive method with a case study design. The results of this study indicate that acupressure point pressure is proven to be effec

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Luria, Oded, Ariel Jaffa, Dan Farine, et al. "Effects of the individual uterine contraction on fetal head descent and cervical dilatation during the active stage of labor." European Journal of Obstetrics & Gynecology and Reproductive Biology 144 (May 2009): S101—S107. http://dx.doi.org/10.1016/j.ejogrb.2009.02.031.

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Nguyen-Ngo, Caitlyn, Carlos Salomon, Andrew Lai, Jane C. Willcox, and Martha Lappas. "Anti-inflammatory effects of gallic acid in human gestational tissues in vitro." Reproduction 160, no. 4 (2020): 561–78. http://dx.doi.org/10.1530/rep-20-0249.

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Spontaneous preterm birth is the leading cause of neonatal mortality and morbidity globally. Activation of the maternal immune system leads to a downstream cascade of proinflammatory events that culminate in the activation of spontaneous uterine contractions and the rupture of the foetal membranes. Anti-inflammatory agents may be a novel therapeutic approach to prevent inflammation-induced myometrial contractions and premature rupture of foetal membranes. The polyphenol gallic acid has been previously shown to exert potent anti-inflammatory effects. Thus, this study aimed to determine the effe

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Hafeez, Sabahat, Javeria Saquib, and Farea Ahmed. "Intrauterine vacuum-induced hemorrhage-control device: A novel approach for PPH." Journal of the Pakistan Medical Association 73, no. 9 (2023): 1931–32. http://dx.doi.org/10.47391/jpma.9602.

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Madam, Postpartum haemorrhage (PPH), defined as postpartum blood loss of > 1000 mL, is a life-threatening emergency and the leading cause of maternal mortality accounting for 25% of maternal deaths worldwide (1). PPH can lead to significant morbidity, including shock, ARDS, coagulopathy, infertility due to hysterectomy, and even mortality (4). Uterine atony is the most common cause, accounting for 80% of all cases of PPH (1) (2). Active management of the third stage of labour consisting of a triad of oxytocin, controlled cord traction, and uterine massage can reduce the incidence of PPH by

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Nur Anita, Raehan, and Sarini Ganing. "KOMPRES AIR HANGAT DAN NYERI PERSALINAN." Bina Generasi : Jurnal Kesehatan 15, no. 1 (2023): 22–28. http://dx.doi.org/10.35907/bgjk.v15i1.300.

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Labor pain is a physiological condition, pain comes from uterine contraction and cervical dilation. Labor pain can affect the mother’s condition in the form of fatigue fear, worry and stress, stress can cause weakening of unterine contractions and result in prolongen labor.Giving warm water compresses is one method to reduce labor pain in maternity mothers. The purpose of the preparation of this final project is to find out whether there is an effect of using warm water compresses in reducing labor pain in mothers during the active phase of labor at the Banggae 1 Majene public health center. T

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Rai, Rakhi, and Sulabha Joshi. "To compare the safety, efficacy and tolerance of intravaginal PGE 1 tab with intravaginal PGE 2 gel in induction of labour." Panacea Journal of Medical Sciences 7, no. 1 (2017): 31–34. https://doi.org/10.18231/2348-7682.2017.0009.

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Induction of labour is an intervention designed to artificially initiate uterine contractions leading to progressive dilatation and effacement of the cervix and birth of the baby. There are various methods of induction of labour. Locally applied PGs have been thought to be most physiological in initiating the process of labour by promoting both cervical ripening and myometrial contraction the present study was carried out to compare the efficacy, safety and tolerance of intravaginal misoprostol (PGE1) tablets with intravaginal dinoprostone (PGE2) gel for cervical ripening and labour induction

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Sitorus, Juli, Ova Emilia, and Detty Siti Nurdiati. "Pengaruh Pemberian Parasetamol Intravena untuk Mengurangi Nyeri Persalinan Kala 1 Fase Aktif." Jurnal Kesehatan Reproduksi 7, no. 1 (2020): 6. http://dx.doi.org/10.22146/jkr.53482.

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Background: Labor was a physiological process, labor pain appeared from regularly uterine contraction, cervix distention and pressure to pelvic floor that stimulate free end nerves. Pain labor can influenced the mother, fetus and the progress of labor. There are various of effort to decrease pain labor by pharmacological or non pharmacological. The best therapy must be safe, effective, and minimal adverse effect to mother and fetus.Objective: To evaluate the effect of paracetamol intraveneous for pain relief in active labor versus saline water.Methods: In randomized controlled trial, with sing

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Carlisa, Belinda. "Comparison of carbetocin with other uterotonic agents in preventing postpartum hemorrhage." International Journal of Reproduction, Contraception, Obstetrics and Gynecology 7, no. 12 (2018): 5207. http://dx.doi.org/10.18203/2320-1770.ijrcog20184997.

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Postpartum hemorrhage (PPH) is defined as blood loss of at least 500 ml or more after vaginal delivery and 1000 ml or more after abdominal delivery. It contributes up to 28% of maternal mortality worldwide and 30.3% of maternal death in Indonesia. 70% cases of PPH are caused by uterine atony. PPH can be prevented by doing routine use of uterotonic agents in active management of third stage of labour. Uterotonic agents that currently available are oxytocin, carbetocin, methylergometrine, syntometrine, misoprostol and carboprost. Carbetocin (a long-acting synthetic analogue of oxytocin) is a new

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Berdai, Mohamed Adnane, Smael Labib, and Mustapha Harandou. "Peganum harmalaL. Intoxication in a Pregnant Woman." Case Reports in Emergency Medicine 2014 (2014): 1–3. http://dx.doi.org/10.1155/2014/783236.

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Peganum harmalaL. is a plant widely distributed in the Mediterranean region. It is commonly used in traditional medicine in Morocco as sedative and abortifacient but exposes users to the risk of overdose and poisoning. The pharmacologically active compounds of this plant include a number ofβ-carboline and quinazoline alkaloids responsible of its pharmacological and toxicological effects. We report the case of a 24-year-old woman, 22 weeks pregnant, intoxicated with the seeds ofPeganum harmalaL. On admission, she had disturbance of consciousness, uterine contraction, and oliguria. Laboratory te

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Welton, Andrew. "Reduction of maternal and neonatal harm through prevention of the primary Cesarean section." University of Western Ontario Medical Journal 85, no. 2 (2016): 19–21. http://dx.doi.org/10.5206/uwomj.v85i2.2222.

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While there are clear life-saving indications for Cesarean section (C-section), rates of this procedure have seen a continued rise without a concomitant improvement in maternal or neonatal outcomes. There is some evidence that outcomes may actually be worse for low-risk C-sections versus vaginal delivery. However, this is not necessarily common knowledge for healthcare providers, and therefore, their patients. Measures to safely reduce the C-section rate target management of labour arrest and specific indications for progression to C-section. In the active phase of the first stage of labour, C

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Clark, J. F., Z. Khuchua, A. Kuznetsov, V. A. Saks, and R. Ventura‐Clapier. "Compartmentation of creatine kinase isoenzymes in myometrium of gravid guinea‐pig." Journal of Physiology 466, no. 1 (1993): 553–72. http://dx.doi.org/10.1113/jphysiol.1993.sp019734.

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1. This study was performed to investigate the possible presence and role of the creatine kinase (CK) system in the contraction and relaxation of skinned guinea‐pig uterus as well as the changes of the CK system during gestation. Experiments were performed on isolated longitudinal fibres of gravid and non‐gravid myometrium. 2. Total CK activity increased from 74 +/‐ 11 to 196 +/‐ 39 IU (g wet wt)‐1 during gestation. 3. The four isoenzymes of CK: muscle (MM), muscle‐brain (MB), brain (BB) and mitochondrial (mt‐CK) were found in myometrium. MM, MB and BB isoenzymes represented respectively 20.3

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Botasheva, Tatyana L., Inga M. Kotieva, Anahit K. Grigoryan, et al. "The principle of morpho-functional symmetry-asymmetry in the formation of contractile activity of the uterus during physiological and complicated pregnancy." Journal of Volgograd State Medical University 21, no. 4 (2024): 117–24. https://doi.org/10.19163/1994-9480-2024-21-4-117-124.

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The functional pairing of the uterus determines the formation of localized and generalized forms of uterine activity, the study of which makes it possible to identify contractile predictors of preterm birth. Normally, uterine contractions first occur in the II–III trimesters of pregnancy and their aim is to ensure an optimal level of blood flow and transplacental exchange in the uteroplacental complex within the framework of the uteroplacental “pump”. It is of value importance to search those forms of uterine contractions that accompany preterm labor. Since uterine contractions are initiated p

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Puspitasari, Lina, and Ernawati . "MANFAAT PENGUATAN OTOT ABDOMEN DAN PEMIJATAN LUMBAL TERHADAP PERCEPATAN PROSES PERSALINAN KALA I." Jurnal Kebidanan 10, no. 01 (2018): 17. http://dx.doi.org/10.35872/jurkeb.v10i01.295.

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ABSTRAKPersalinan lama akan berdampak buruk pada ibu dan janin, hal ini dapat berakibat pada kematian. Penyebab permasalahan tersebut adalah kurang adekuatnya kontraksi uterus. Latihan penguatan otot abdomen dan pemijatan lumbal dapat dijadikan solusi dalam penyelesaian masalah tersebut. Tujuan penelitian ini untuk mengetahui manfaat penguatan otot abdomen dan pemijatan lumbal terhadap percepatan lamanya proses persalinan Kala I yang dihitung nilai rata-rata lama pembukaan serviks dari 0 cm sampai dengan 10 cm. Metode penelitian ini adalah eksperimen semu jenis one group without control design

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Dumitrescu, Bogdan Constantin, Ligia Gabriela Tataranu, and Mircea Radu Gorgan. "Pregnant woman with an intracranial meningioma – case report and review of the literature." Romanian Neurosurgery 21, no. 4 (2014): 489–96. http://dx.doi.org/10.2478/romneu-2014-0067.

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Abstract It is about a 33-year-old female, with a 36 weeks uncomplicated pregnancy and with signs of increased intracranial pressure. Hours after admission and an obstetric evaluation, uterine contraction started and the patient was taken to the delivery room, where she presented a partial motor seizure on the left side with secondary generalization and urine emission. A caesarean section was performed without fetal or maternal complications. The urgent MRI gadolinium-enhanced brain scan revealed a 39/50/54 mm tumoral mass having an aspect of an anterior third falx cerebri meningioma. The pati

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Faesol, Moh, and Windha Widyastuti. "Literature Review : Penerapan Metode Kompres Hangat Dalam Menurunkan Intensitas Nyeri Ibu Bersalin Kala 1 Fase Aktif." Prosiding Seminar Nasional Kesehatan 1 (December 21, 2021): 1721–26. http://dx.doi.org/10.48144/prosiding.v1i.921.

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AbstractThe unproper handied labour pain may ancrease blood pressure as well as oxygen demand, and decrease uterine contraction. Warm compress is a method that can be applied to reduce the intensity of pain during labour. this scientific report was written to describe the application of warm compresses to reduce the intensity of maternal pain during the first active phase of labour based on a literature review. this literature review was constructed by analyzing 3 articles takeen from Google Scholar with "labour pain", "firts active phase" and "warm compresses" the keywords, in the form of ful

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